Stanford vs Clemson Prediction — AI Finds CAN'T MISS CFB Lines & Props (Sep 28)
Updated: 2024-09-21T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The Stanford Cardinal (2-1) face off against the Clemson Tigers (2-1) in a primetime ACC matchup on September 28, 2024, at Memorial Stadium. Clemson, heavily favored by over 21 points, looks to solidify its ACC standing against a resilient Stanford team.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Sep 28, 2024
Start Time: 7:00 PM EST
Venue: Memorial Stadium
Tigers Record: (2-1)
Cardinal Record: (2-1)
OPENING ODDS
STNFRD Moneyline: +963
CLEM Moneyline: -1887
STNFRD Spread: +21.5
CLEM Spread: -21.5
Over/Under: 57.5
STNFRD
Betting Trends
- Stanford has posted a strong 2-0 ATS record this season, consistently covering the spread in their outings despite being underdogs in many matchups.
CLEM
Betting Trends
- Clemson has struggled ATS, going 1-2 this season, underperforming relative to their heavy favoritism in most games.
MATCHUP TRENDS
- Stanford has covered the spread in two of their last three road games, while Clemson has failed to cover in four of their last five home games.
STNFRD vs. CLEM
Best Prop Bet
- Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.
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Stanford vs Clemson Prediction & Odds:
Free CFB Betting Insights for 9/28/24
Their offense has been explosive, particularly their ground game, where they’ve dominated opponents with a combination of speed and power. Quarterback Cade Klubnik has managed the offense efficiently, and running back Phil Mafah has been a standout performer. Defensively, Clemson has shown vulnerability, particularly in their most recent outing, where they allowed 35 points to NC State. Both teams come into this game with significant implications. Stanford looks to maintain momentum and prove they can compete with the top teams in the ACC, while Clemson aims to reassert their dominance within the conference. Despite Clemson being a clear favorite, Stanford has shown the ability to punch above their weight class, especially when facing larger spreads. This game could be decided by whether Stanford’s defense can contain Clemson’s explosive attack or if Clemson can shore up their defensive issues and put away the Cardinal early.
Recognizing an individual as the absolute best football scholar-athlete in the nation-- combining academic success, football performance and exemplary leadership.
— Stanford Football (@StanfordFball) September 25, 2024
We can't think of anyone more fitting than Tristan.
Congrats to Tristan Sinclair, named a William V. Campbell… pic.twitter.com/D0taHinrGF
Stanford Cardinal CFB Preview
Stanford enters the game with a 2-1 record and a solid 2-0 ATS record, showing that they have the ability to compete, especially as underdogs. Ashton Daniels has been a steady presence at quarterback, leading the team with both his arm and legs. His favorite target, Elic Ayomanor, has been a reliable receiver, catching key passes and contributing significantly to the team’s offensive success. The Cardinal’s ground game has also been a strength, with Chris Davis Jr. leading the way with an average of nearly 8.8 yards per carry. Defensively, Stanford has been a mixed bag. While they were able to stifle Syracuse’s rushing attack in their most recent win, their pass defense has been a weak spot, giving up over 300 yards through the air. This will be a key area of concern as they face Clemson, whose offense is among the most potent in the ACC. Stanford will need to tighten up their secondary and limit big plays if they want to keep this game close. While they are significant underdogs (+21.5), Stanford has shown resilience in covering large spreads. They’ve managed to cover in two of their last three road games, showing they can keep games competitive, even against stronger opponents. The key for Stanford will be to play mistake-free football and capitalize on any defensive lapses Clemson shows, particularly in the secondary.

Credit: USA TODAY/IMAGN
Clemson Tigers CFB Preview
The Clemson Tigers are coming into this matchup with a 2-1 record, but their season has been a tale of two teams. Offensively, Clemson has been firing on all cylinders, especially in their running game. The Tigers put up a massive 270 rushing yards in their most recent win over NC State, where they racked up 59 points. Phil Mafah has been their primary weapon on the ground, averaging over 15 yards per carry in his last game. Quarterback Cade Klubnik has also been effective, completing nearly 67% of his passes and avoiding turnovers. However, Clemson’s defense has shown signs of weakness, especially in stopping the run and defending against the pass. They allowed NC State to score 35 points and accumulate over 440 yards of offense. This could be an area of concern as Stanford’s offense has been capable of moving the ball effectively, particularly through the air. The Tigers’ ATS record is also troubling, having covered the spread only once in their first three games this season. Clemson has traditionally struggled to cover large spreads, particularly at home, where they are 1-4 ATS in their last five games. Despite these struggles, Clemson’s talent and depth, particularly on the offensive side, make them the clear favorites in this matchup. If their defense can step up and limit Stanford’s playmakers, the Tigers should have little trouble securing the win.
It's Homecoming week and we're feeling nostalgic. Time to revisit some of our favorite Homecoming videos from the last few years.🐅🏡
— Clemson Football (@ClemsonFB) September 25, 2024
2017 - Home pic.twitter.com/GiZSSj7u8C
Stanford vs. Clemson Prop Picks (AI)
Stanford vs. Clemson Prediction (AI)

Remi, our AI sports genius, has been pouring over millions of data from every facet between the Cardinal and Tigers and using recursive machine learning and impressive AI to analyze the data to a single cover probability.
Interestingly enough, the data has been most keyed in on the linear correlation of weight knucklehead sportsbettors regularly put on Clemson’s strength factors between a Cardinal team going up against a possibly strong Tigers team. In reality, the true game analytics might reflect a strong lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our CFB AI picks for FREE now.
Below is our current AI Stanford vs Clemson picks, computer picks Cardinal vs Tigers, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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ACTIVE PICKS LOCKED - SEE NOW |
These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full CFB schedule.
Cardinal Betting Trends
Stanford has posted a strong 2-0 ATS record this season, consistently covering the spread in their outings despite being underdogs in many matchups.
Tigers Betting Trends
Clemson has struggled ATS, going 1-2 this season, underperforming relative to their heavy favoritism in most games.
Cardinal vs. Tigers Matchup Trends
Stanford has covered the spread in two of their last three road games, while Clemson has failed to cover in four of their last five home games.
Stanford vs. Clemson Game Info
What time does Stanford vs Clemson start on September 28, 2024?
Stanford vs Clemson starts on September 28, 2024 at 7:00 PM EST.
Where is Stanford vs Clemson being played?
Venue: Memorial Stadium.
What are the opening odds for Stanford vs Clemson?
Spread: Clemson -21.5
Moneyline: Stanford +963, Clemson -1887
Over/Under: 57.5
What are the records for Stanford vs Clemson?
Stanford: (2-1) | Clemson: (2-1)
What is the AI best bet for Stanford vs Clemson?
Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.. Prices move—always shop for the best number.
What are Stanford vs Clemson trending bets?
Stanford has covered the spread in two of their last three road games, while Clemson has failed to cover in four of their last five home games.
What are Stanford trending bets?
STNFRD trend: Stanford has posted a strong 2-0 ATS record this season, consistently covering the spread in their outings despite being underdogs in many matchups.
What are Clemson trending bets?
CLEM trend: Clemson has struggled ATS, going 1-2 this season, underperforming relative to their heavy favoritism in most games.
Where can I find AI Picks for Stanford vs Clemson?
See our latest CFB picks and odds pages for 2024 to compare prices before you bet.
Stanford vs. Clemson Odds
Remi is pouring through tons of stats on each line. In fact, anytime the Stanford vs Clemson trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme altitude rarely follow normal, predictable betting trends.
Stanford vs Clemson Opening Odds
STNFRD Moneyline:
+963 CLEM Moneyline: -1887
STNFRD Spread: +21.5
CLEM Spread: -21.5
Over/Under: 57.5
Stanford vs Clemson Live Odds
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Oct 25, 2025 12:00PM EDT
Bowling Green Falcons
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O 48.5 (-108)
U 48.5 (-112)
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Oct 25, 2025 12:00PM EDT
Rutgers Scarlet Knights
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Oct 25, 2025 12:00PM EDT
UCLA Bruins
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O 43.5 (-110)
U 43.5 (-110)
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Oct 25, 2025 12:00PM EDT
Ohio Bobcats
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-500
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O 59.5 (-102)
U 59.5 (-118)
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Oct 25, 2025 12:00PM EDT
SMU Mustangs
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U 54.5 (-112)
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Oct 25, 2025 12:00PM EDT
Syracuse Orange
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Oct 25, 2025 12:00PM EDT
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Oct 25, 2025 12:00PM EDT
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O 54.5 (-110)
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Oct 25, 2025 12:00PM EDT
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U 56.5 (-105)
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Oct 25, 2025 12:45PM EDT
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U 39.5 (-112)
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O 62.5 (-112)
U 62.5 (-108)
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Oct 25, 2025 3:30PM EDT
Illinois Fighting Illini
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+164
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O 46.5 (-115)
U 46.5 (-105)
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Oct 25, 2025 3:30PM EDT
San Diego State Aztecs
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U 48.5 (-115)
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Missouri Tigers
Vanderbilt Commodores
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–
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+124
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O 51.5 (-115)
U 51.5 (-105)
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Oct 25, 2025 3:30PM EDT
NC State Wolfpack
Pittsburgh Panthers
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|
–
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+205
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+6.5 (-108)
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O 56.5 (-110)
U 56.5 (-110)
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Oct 25, 2025 3:30PM EDT
Western Michigan Broncos
Miami Ohio Redhawks
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–
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+114
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O 40.5 (-118)
U 40.5 (-102)
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Oct 25, 2025 3:30PM EDT
UL Monroe Warhawks
USM Golden Eagles
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–
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+390
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+12.5 (-112)
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O 50.5 (-112)
U 50.5 (-108)
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Oct 25, 2025 4:00PM EDT
Oklahoma State Cowboys
Texas Tech Red Raiders
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OKLAST
TXTECH
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–
–
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+3500
-10000
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+38.5 (-115)
-38.5 (-105)
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O 56.5 (-108)
U 56.5 (-112)
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Oct 25, 2025 4:00PM EDT
Baylor Bears
Cincinnati Bearcats
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BAYLOR
CINCY
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–
–
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+170
-205
|
+4.5 (-110)
-4.5 (-110)
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O 67.5 (-108)
U 67.5 (-112)
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Oct 25, 2025 4:15PM EDT
Texas Longhorns
Mississippi State Bulldogs
10/25/25 4:15PM
TEXAS
MISSST
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–
–
|
-270
+220
|
-7 (-105)
+7 (-115)
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O 45.5 (-105)
U 45.5 (-115)
|
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Oct 25, 2025 6:00PM EDT
TCU Horned Frogs
West Virginia Mountaineers
10/25/25 6PM
TCU
WVU
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–
–
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-700
+500
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-14.5 (-112)
+14.5 (-108)
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O 55.5 (-112)
U 55.5 (-108)
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Oct 25, 2025 7:00PM EDT
Wisconsin Badgers
Oregon Ducks
10/25/25 7PM
WISC
OREG
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–
–
|
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+33.5 (-108)
-33.5 (-112)
|
O 44.5 (-120)
U 44.5 (+100)
|
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Oct 25, 2025 7:00PM EDT
Louisiana Ragin Cajuns
Troy Trojans
10/25/25 7PM
UL
TROY
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–
–
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+280
-355
|
+8.5 (-108)
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O 47.5 (-110)
U 47.5 (-110)
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Oct 25, 2025 7:00PM EDT
Stanford Cardinal
Miami Hurricanes
10/25/25 7PM
STNFRD
MIAMI
|
–
–
|
+3500
-10000
|
+30.5 (-115)
-30.5 (-105)
|
O 45.5 (-108)
U 45.5 (-112)
|
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Oct 25, 2025 7:00PM EDT
Georgia Southern Eagles
Arkansas State Red Wolves
10/25/25 7PM
GASO
ARKST
|
–
–
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+114
-135
|
+2.5 (-112)
-2.5 (-108)
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O 62.5 (-110)
U 62.5 (-110)
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Oct 25, 2025 7:30PM EDT
Michigan Wolverines
Michigan State Spartans
10/25/25 7:30PM
MICH
MICHST
|
–
–
|
-600
+440
|
-14 (-110)
+14 (-110)
|
O 47.5 (-115)
U 47.5 (-105)
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Oct 25, 2025 7:30PM EDT
Texas A&M Aggies
LSU Tigers
10/25/25 7:30PM
TEXAM
LSU
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–
–
|
-135
+114
|
-2.5 (-115)
+2.5 (-105)
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O 47.5 (-115)
U 47.5 (-105)
|
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Oct 25, 2025 7:30PM EDT
Boston College Eagles
Louisville Cardinals
10/25/25 7:30PM
BC
LVILLE
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–
–
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+1200
-2400
|
+25.5 (-110)
-25.5 (-110)
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O 55.5 (-102)
U 55.5 (-118)
|
|
Oct 25, 2025 7:30PM EDT
Colorado State Rams
Wyoming Cowboys
10/25/25 7:30PM
COLOST
WYO
|
–
–
|
+190
-230
|
+6 (-110)
-6 (-110)
|
O 46.5 (-112)
U 46.5 (-108)
|
|
Oct 25, 2025 7:45PM EDT
Tennessee Volunteers
Kentucky Wildcats
10/25/25 7:45PM
TENN
UK
|
–
–
|
-345
+275
|
-9.5 (-108)
+9.5 (-112)
|
O 54.5 (-110)
U 54.5 (-110)
|
|
Oct 25, 2025 8:00PM EDT
Houston Cougars
Arizona State Sun Devils
10/25/25 8PM
HOU
ARIZST
|
–
–
|
+245
-305
|
+7.5 (-108)
-7.5 (-112)
|
O 47.5 (-102)
U 47.5 (-118)
|
|
Oct 25, 2025 10:15PM EDT
Colorado Buffaloes
Utah Utes
10/25/25 10:15PM
COLO
UTAH
|
–
–
|
+410
-550
|
+13.5 (-110)
-13.5 (-110)
|
O 49.5 (-112)
U 49.5 (-108)
|
CFB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Stanford Cardinal vs. Clemson Tigers on September 28, 2024 at Memorial Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our CFB odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
FSU@STNFRD | STNFRD +18 | 56.6% | 6 | WIN |
WASHST@UVA | WASHST +17.5 | 58.8% | 8 | WIN |
NEVADA@NMEX | NEVADA +13.5 | 57.8% | 7 | WIN |
TEXAS@UK | ARCH MANNING UNDER 1.5 PASS TD | 56.1% | 6 | WIN |
ARMY@TULANE | ARMY +10 | 55.3% | 5 | WIN |
SJST@UTAHST | SJST +4 | 54.4% | 4 | LOSS |
LVILLE@MIAMI | LVILLE +12.5 | 56.5% | 6 | WIN |
LVILLE@MIAMI | CJ DANIELS UNDER 4.5 RECEPTIONS | 54.4 | 4 | LOSS |
DEL@JAXST | DEL -2.5 | 57.6% | 6 | LOSS |
UTEP@SAMST | UTEP -2.5 | 53.9% | 3 | WIN |
FIU@WKY | FIU +10.5 | 54.6% | 4 | WIN |
ARKST@SALA | ARKST +7.5 | 54.5% | 4 | WIN |
ARKST@SALA | JAYLEN RAYNOR UNDER 40.5 LONGEST PASS COMP | 53.3% | 3 | WIN |
SJST@WYO | SJST -120 | 59.8% | 7 | LOSS |
UMASS@KENTST | KENTST -135 | 60.2% | 6 | WIN |
NOILL@EMICH | EMICH +2.5 | 53.9% | 3 | WIN |
BYU@ARIZ | ARIZ +2.5 | 54.2% | 3 | LOSS |
OKLA@TEXAS | OKLA +2.5 | 54.7% | 4 | LOSS |
NMEX@BOISE | NMEX +16.5 | 56.4% | 6 | WIN |
WAKE@OREGST | WAKE -2.5 | 56.7% | 6 | WIN |
ULMON@COASTAL | ULMON -2.5 | 56.8% | 6 | LOSS |
IOWA@WISC | WISC +4 | 54.8% | 4 | LOSS |
TOLEDO@BGREEN | TOLEDO -10 | 56.3% | 6 | LOSS |
SFLA@NOTEX | SFLA +2.5 | 54.3% | 4 | WIN |
FRESNO@COLOST | RICHIE ANDERSON III LONGEST RECEPTION UNDER 16.5 | 54.4% | 4 | LOSS |
JAXST@SAMST | SAMST +7.5 | 55.3% | 5 | WIN |
USM@GAS | GAS +3.5 | 57.4% | 7 | WIN |
LIB@UTEP | UTEP +2 | 54.5% | 4 | LOSS |
SALA@TROY | SALA -118 | 55.2% | 4 | LOSS |
TULSA@MEMP | MEMP -20.5 | 53.8% | 3 | WIN |
JMAD@GAST | GAST +20.5 | 54.6% | 4 | WIN |
WAKE@VATECH | VATECH -5.5 | 56.6% | 6 | LOSS |
UNLV@WYO | WYO +4.5 | 55.5% | 5 | LOSS |
PSU@UCLA | PSU -24.5 | 56.3% | 6 | LOSS |
TXSTSM@ARKST | TXSTSM -13 | 56.7% | 6 | LOSS |
UVA@LVILLE | ISAAC BROWN OVER 70.5 RUSH YDS | 56.6% | 6 | LOSS |
WVU@BYU | WVU +20.5 | 54.7% | 4 | WIN |
SAMST@NMEXST | SAMST -1.5 | 54.1% | 3 | LOSS |
EMICH@CMICH | CMICH -148 | 62.8% | 7 | WIN |
SDGST@NOILL | SDGST -118 | 55.7% | 3 | WIN |
BAMA@GEORGIA | GEORGIA -125 | 58.7% | 7 | LOSS |
TENN@MISSST | MISSST +7.5 | 54.3% | 4 | WIN |
UK@SC | SC -5.5 | 54.8% | 4 | WIN |
WKY@MIZZST | MIZZST +4.5 | 55.6% | 6 | LOSS |
JAXST@USM | USM -3.5 | 56.0% | 5 | WIN |
NMEXST@NMEX | NMEX -14.5 | 56.9% | 6 | WIN |
ARIZ@IOWAST | ROCCO BECHT UNDER 1.5 PASS TDS | 55.5% | 5 | WIN |
TCU@ARIZST | JOSH HOOVER PASS YDS UNDER 287.5 | 53.4% | 3 | WIN |
ARIZST@BAYLOR | BAYLOR -130 | 58.4% | 6 | LOSS |
WYO@COLO | WYO +13.5 | 54.1% | 3 | LOSS |
TULANE@OLEMISS | MISS -11.5 | 54.3% | 4 | WIN |