Royals vs. Angels
Prediction, Odds & Props
Sep 23 | MLB AI Picks
Updated: 2025-09-21T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The Kansas City Royals (78-78) visit the Angels in Anaheim, seeking to stay above .500 and continue the momentum from recent offensive performances, while the Angels (70-86) are playing out the string with little postseason hope but plenty of pride. With Royals favored (-130) and an over/under around 8 runs, expectations are for a competitive game with moderate scoring, especially if both starters are hittable or the offenses find rhythm.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Sep 23, 2025
Start Time: 9:38 PM EST
Venue: Angel Stadium of Anaheim
Angels Record: (70-86)
Royals Record: (78-78)
OPENING ODDS
KC Moneyline: -153
LAA Moneyline: +128
KC Spread: -1.5
LAA Spread: +1.5
Over/Under: 8.5
KC
Betting Trends
- Kansas City has shown flashes of strong value recently by covering spreads in games where their offense breaks out, such as the 20-1 rout of the Blue Jays, which highlighted their ability to dominate when swinging well. While their record is near .500, bettors have noted that Royals games tend to outperform expectations when their bats are hot and their starter holds form.
LAA
Betting Trends
- The Angels are 16-14 against the run line at home this season, showing modest success in covering smaller spreads but also signaling vulnerability in many matchups. In their last 10 home games, their ATS record is slightly below even, with 4 wins and 6 losses, indicating that home field hasn’t always translated into consistent performance versus expectations.
MATCHUP TRENDS
- The moneyline has Kansas City at roughly -130, meaning they are slight favorites despite playing on the road, which suggests public confidence in their offense and recent run production. The over/under around 8 runs reflects expectation for a moderate scoring game; value may lie in taking the over if either starter falters early or if the Angels struggle to limit damage. Angels underdog run line value exists, given their decent record as home underdogs (28-13 run-line since April 15), but only if they can stay within reach late. Royals’ recent big offensive outbursts signal upside, but they’ll need consistency through the lineup.
KC vs. LAA
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: B. Witt over 1.5 Hits+Runs+RBI.
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Kansas City vs Los Angeles Prediction & Odds:
Free MLB Betting Insights for 9/23/25
On the mound, the Royals’ starter will be tasked with pounding the strike zone and working efficiently, because forcing the Angels to string hits together rather than gifting them free bases is the best way to neutralize their lineup. The Angels, meanwhile, have spent the year plagued by inconsistencies, but they still have enough talent to spoil a game if Kansas City is sloppy, with Mike Trout capable of changing a contest in one swing and younger pieces like Zach Neto showing flashes of growth that the organization hopes will carry into the future. Defensively, Los Angeles has not been sharp enough this year, and that has been a major reason they’ve struggled to win close games, but playing at home with nothing to lose sometimes produces looser, more confident play. The Royals cannot afford to take them lightly, because in a ballpark like Angel Stadium, momentum can swing quickly if mistakes lead to multi-run innings. From a betting perspective, Kansas City enters as the safer play on the moneyline at around -130, but their near-.500 record underscores the volatility of their season, making a run-line cover far from guaranteed. The total of 8 runs points toward expectations of moderate scoring, but with both lineups capable of punishing shaky pitching, an over could easily cash if either starter falters. Ultimately, this matchup will come down to whether Kansas City can build on their recent offensive surge and play with the urgency of a team trying to finish strong, or whether the Angels, despite their record, can find enough energy and pride at home to disrupt the Royals’ rhythm and force them into the kind of inconsistent game that has been their weakness all year.
Career RBI No. 1,012.
— Kansas City Royals (@Royals) September 21, 2025
Salvador Perez has tied Hal McRae for 2nd in RBIs on the Royals franchise leaderboard! pic.twitter.com/Uh5at85w81
Kansas City Royals MLB Preview
The Kansas City Royals enter Angel Stadium on September 23, 2025, with the confidence of a team that has shown flashes of dominance down the stretch and the urgency of one that wants to close out the year above .500, using games like this against the Angels as both a measuring stick and an opportunity to build momentum for the future. Kansas City has been an unpredictable squad this season, but when their offense clicks, it can be overwhelming, as demonstrated by their recent 20-1 blowout win over Toronto that showcased the kind of top-to-bottom production they are capable of generating. Vinnie Pasquantino remains a centerpiece in the lineup, offering both power and consistency, while younger contributors like Carter Jensen and Michael Massey have helped lengthen the order and give the Royals multiple avenues for run production. Against an Angels pitching staff that has struggled all year with depth and command, the Royals’ approach must be to stay patient at the plate, work counts, and cash in on mistakes rather than stranding runners, which has often been their Achilles’ heel in tighter games.
On the mound, Kansas City’s starter will need to be efficient, limiting walks and keeping the ball in the park, because the Angels’ offense, while inconsistent, still features Mike Trout and a handful of younger hitters like Zach Neto who can do damage if given extra opportunities. The bullpen has been hit or miss for Kansas City, so any length their starter can provide will be crucial in maintaining stability and giving manager Matt Quatraro the flexibility to match up late if the game is close. Defensively, the Royals need to stay sharp and avoid the unforced errors that have cost them games, because their path to victory relies on forcing the Angels to earn every run rather than handing them momentum with sloppy play. From a betting perspective, Kansas City enters as slight favorites around -130, a reflection of both their stronger record and their recent offensive form, though their inconsistency makes them a risky run-line choice; still, they have more than enough firepower to cover if their bats get going early. The total of eight runs also points to the potential for offense, and given how Kansas City has been scoring in bunches lately, the over could be appealing if the Angels’ pitchers struggle. Ultimately, the Royals’ formula for success is simple: ride their hot bats, get a steady start, and stay disciplined defensively. If they execute that plan, they should leave Anaheim with another win, but if their offense cools or their bullpen falters, they could easily allow a struggling Angels team to hang around longer than expected.

Credit: USA TODAY/IMAGN
Los Angeles Angels MLB Preview
The Los Angeles Angels take the field at Angel Stadium on September 23, 2025, trying to salvage pride from a season that has long since slipped out of playoff contention, but with the chance to play spoiler against a Kansas City Royals team still pushing to finish above .500. For the Angels, the story of the year has been inconsistency: their rotation has struggled to provide length, the bullpen has too often crumbled under pressure, and defensive miscues have magnified those issues, leaving them with one of the weakest overall records in the American League. Still, they retain dangerous pieces in their lineup, starting with Mike Trout, who despite his age remains capable of delivering game-changing swings, and supported by younger contributors like Zach Neto and Logan O’Hoppe, who have shown growth and flashed the potential to be building blocks for the future. To beat the Royals, Los Angeles will need its starting pitcher—whoever gets the call—to limit walks and keep hitters like Vinnie Pasquantino and Michael Massey from igniting big innings, something that has plagued Angels pitchers all year. At the plate, their hitters must be opportunistic, taking advantage of Kansas City’s defensive lapses or bullpen instability, and avoiding the long stretches of quiet innings that have so often doomed them in 2025.
The Angels’ bullpen is still a liability, so keeping games close into the middle innings is vital if they hope to pull off an upset, and the home crowd could provide an extra boost if the offense gives them something to cheer about early. Defensively, Los Angeles must be sharper than they have been, because the Royals have shown they can pour on runs if given extra outs, and late-season games like this often hinge on which team avoids the big mistake. From a betting perspective, the Angels are home underdogs, offering some run-line appeal given their 28-13 run-line record as home dogs since midseason, but their outright chances are slim unless their pitching staff surprises with a strong showing. The total of eight runs is reasonable, as both teams are capable of scoring, and if Kansas City’s bats stay hot and the Angels contribute, the over could be in play. Ultimately, for Los Angeles to come away with a win, they must combine a clean start, timely hitting from Trout and their young core, and rare reliability from their bullpen—otherwise, their role may once again be reduced to spoiler as Kansas City looks to finish the year on a high note.
Nacido en Colombia 🇨🇴#HispanicHeritageMonth x @donjulio pic.twitter.com/elmIDxItLY
— Los Angeles Angels (@Angels) September 22, 2025
Kansas City vs. Los Angeles Prop Picks (AI)
Kansas City vs. Los Angeles Prediction (AI)

Remi, our AI sports algorithm, has been pouring over tons of data from every simulation between the Royals and Angels and using recursive machine learning and industry leading AI to examine the data to a single cover probability.
Interestingly enough, the data has been most keyed in on the growing factor knucklehead sportsbettors regularly put on coaching factors between a Royals team going up against a possibly unhealthy Angels team. Trends look to say the true game analytics might reflect a slight lean against one Vegas line specifically.
Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.
Below is our current AI Kansas City vs Los Angeles picks, computer picks Royals vs Angels, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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MLB | 10/1 | SD@CHC | UNLOCK THIS PICK | 4 |
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MLB | 10/1 | SD@CHC | UNLOCK THIS PICK | 4 |
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MLB | 10/1 | CIN@LAD | UNLOCK THIS PICK | 3 |
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MLB | 10/1 | CIN@LAD | UNLOCK THIS PICK | 2 |
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MLB | 10/1 | DET@CLE | UNLOCK THIS PICK | 2 |
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MLB | 10/1 | DET@CLE | UNLOCK THIS PICK | 1 |
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MLB | 10/1 | BOS@NYY | UNLOCK THIS PICK | 1 |
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MLB | 10/1 | CIN@LAD | GET FREE PICK NOW | 1 | – | |
MLB | 10/1 | BOS@NYY | UNLOCK THIS PICK | 0 |
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MLB | 10/1 | BOS@NYY | GET FREE PICK NOW | 0 | – |
These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.
Royals Betting Trends
Kansas City has shown flashes of strong value recently by covering spreads in games where their offense breaks out, such as the 20-1 rout of the Blue Jays, which highlighted their ability to dominate when swinging well. While their record is near .500, bettors have noted that Royals games tend to outperform expectations when their bats are hot and their starter holds form.
Angels Betting Trends
The Angels are 16-14 against the run line at home this season, showing modest success in covering smaller spreads but also signaling vulnerability in many matchups. In their last 10 home games, their ATS record is slightly below even, with 4 wins and 6 losses, indicating that home field hasn’t always translated into consistent performance versus expectations.
Royals vs. Angels Matchup Trends
The moneyline has Kansas City at roughly -130, meaning they are slight favorites despite playing on the road, which suggests public confidence in their offense and recent run production. The over/under around 8 runs reflects expectation for a moderate scoring game; value may lie in taking the over if either starter falters early or if the Angels struggle to limit damage. Angels underdog run line value exists, given their decent record as home underdogs (28-13 run-line since April 15), but only if they can stay within reach late. Royals’ recent big offensive outbursts signal upside, but they’ll need consistency through the lineup.
Kansas City vs. Los Angeles Game Info
What time does Kansas City vs Los Angeles start on September 23, 2025?
Kansas City vs Los Angeles starts on September 23, 2025 at 9:38 PM EST.
Where is Kansas City vs Los Angeles being played?
Venue: Angel Stadium of Anaheim.
What are the opening odds for Kansas City vs Los Angeles?
Spread: Los Angeles +1.5
Moneyline: Kansas City -153, Los Angeles +128
Over/Under: 8.5
What are the records for Kansas City vs Los Angeles?
Kansas City: (78-78) | Los Angeles: (70-86)
What is the AI best bet for Kansas City vs Los Angeles?
Remi's searched hard and found the best prop for this matchup: B. Witt over 1.5 Hits+Runs+RBI.. Prices move—always shop for the best number.
What are Kansas City vs Los Angeles trending bets?
The moneyline has Kansas City at roughly -130, meaning they are slight favorites despite playing on the road, which suggests public confidence in their offense and recent run production. The over/under around 8 runs reflects expectation for a moderate scoring game; value may lie in taking the over if either starter falters early or if the Angels struggle to limit damage. Angels underdog run line value exists, given their decent record as home underdogs (28-13 run-line since April 15), but only if they can stay within reach late. Royals’ recent big offensive outbursts signal upside, but they’ll need consistency through the lineup.
What are Kansas City trending bets?
KC trend: Kansas City has shown flashes of strong value recently by covering spreads in games where their offense breaks out, such as the 20-1 rout of the Blue Jays, which highlighted their ability to dominate when swinging well. While their record is near .500, bettors have noted that Royals games tend to outperform expectations when their bats are hot and their starter holds form.
What are Los Angeles trending bets?
LAA trend: The Angels are 16-14 against the run line at home this season, showing modest success in covering smaller spreads but also signaling vulnerability in many matchups. In their last 10 home games, their ATS record is slightly below even, with 4 wins and 6 losses, indicating that home field hasn’t always translated into consistent performance versus expectations.
Where can I find AI Picks for Kansas City vs Los Angeles?
See our latest MLB picks and odds pages for 2025 to compare prices before you bet.
Kansas City vs. Los Angeles Odds
AI algorithm Remi is pouring through loads of data points on each player. In fact, anytime the Kansas City vs Los Angeles trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme hostile environments rarely follow normal, predictable patterns.
Kansas City vs Los Angeles Opening Odds
KC Moneyline:
-153 LAA Moneyline: +128
KC Spread: -1.5
LAA Spread: +1.5
Over/Under: 8.5
Kansas City vs Los Angeles Live Odds
Games | PTS | ML | SPR | O/U | |
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Oct 2, 2025 3:08PM EDT
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Cleveland Guardians
10/2/25 3:08PM
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Guardians
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–
–
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+100
-120
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-1.5 (+175)
+1.5 (-215)
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O 7 (-105)
U 7 (-115)
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–
–
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+100
-118
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-1.5 (+172)
+1.5 (-210)
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O 7.5 (-110)
U 7.5 (-110)
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Oct 2, 2025 8:08PM EDT
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New York Yankees
10/2/25 8:08PM
Red Sox
Yankees
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–
–
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+136
-162
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+1.5 (-160)
-1.5 (+130)
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O 7.5 (-120)
U 7.5 (-102)
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Oct 4, 2025 2:30PM EDT
Los Angeles Dodgers
Philadelphia Phillies
10/4/25 2:30PM
Dodgers
Phillies
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–
–
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+110
-130
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pk
pk
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Oct 4, 2025 5:09PM EDT
Los Angeles Dodgers
Philadelphia Phillies
10/4/25 5:09PM
Dodgers
Phillies
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–
–
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+108
-126
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pk
pk
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O 7 (-135)
U 7 (+115)
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MLB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Kansas City Royals vs. Los Angeles Angels on September 23, 2025 at Angel Stadium of Anaheim.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
ARI@SD | SD -131 | 57.3% | 4 | WIN |
DET@BOS | BOS -115 | 56.4% | 5 | WIN |
NYM@CHC | NYM -110 | 54.1% | 3 | WIN |
HOU@ATH | ATH +118 | 50.8% | 4 | WIN |
NYM@CHC | OVER 7 | 54.5% | 3 | WIN |
STL@SF | OVER 7.5 | 55.9% | 5 | LOSS |
KC@LAA | TYLER TOLBERT UNDER 1.5 BASES | 54.4% | 4 | WIN |
MIL@SD | UNDER 9 | 54.7% | 4 | WIN |
MIA@PHI | KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS | 53.3% | 3 | WIN |
WAS@NYM | OVER 8.5 | 56.1% | 6 | LOSS |
LAA@COL | COL +108 | 50.5% | 3 | WIN |
TOR@KC | UNDER 9 | 54.7% | 4 | LOSS |
SEA@KC | KC +1.5 | 62.3% | 5 | LOSS |
NYY@MIN | OVER 9 | 55.1% | 4 | WIN |
MIA@COL | OVER 10.5 | 55.0% | 4 | WIN |
MIA@COL | AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS | 54.3% | 4 | WIN |
SEA@KC | BOBBY WITT UNDER 0.5 SINGLES | 54.4% | 4 | LOSS |
PHI@LAD | LAD -113 | 54.7% | 4 | LOSS |
NYY@BOS | OVER 7.5 | 54.3% | 3 | WIN |
KC@PHI | PHI -130 | 58.3% | 4 | WIN |
LAD@SF | OVER 7.5 | 54.7% | 4 | LOSS |
NYM@PHI | PHI -122 | 55.6% | 4 | WIN |
KC@CLE | KC -104 | 52.0% | 3 | WIN |
CIN@SD | JAKE CRONEWORTH OVER 0.5 HITS | 53.1% | 3 | WIN |
WAS@MIA | MIA -123 | 55.2% | 4 | LOSS |
LAA@KC | UNDER 9.5 | 54.9% | 3 | WIN |
TEX@ARI | UNDER 9 | 54.2% | 4 | WIN |
SF@COL | UNDER 11.5 | 56.4% | 6 | LOSS |
SF@COL | RAFAEL DEVERS OVER 1.5 BASES | 56.1% | 6 | WIN |
MIA@WAS | WAS -110 | 54.4% | 4 | WIN |
NYM@DET | OVER 8.5 | 54.5% | 4 | WIN |
TEX@ARI | UNDER 9.5 | 56.4% | 6 | WIN |
TEX@ARI | ALEJANDRO OSUNA UNDER 1.5 BASES | 54.1% | 4 | LOSS |
ATL@CHC | CHC -116 | 55.1% | 3 | WIN |
PHI@MIL | OVER 8.5 | 55.0% | 3 | WIN |
ARI@LAD | SHOHEI OHTANI OVER 2.5 BASES | 54.2% | 4 | WIN |
SEA@CLE | CLE +1.5 | 57.2% | 3 | WIN |
CHC@SF | CHC -105 | 54.1% | 4 | LOSS |
NYY@CHW | RYAN MCMAHON OVER 0.5 BASES | 54.1% | 4 | WIN |
PHI@NYM | OVER 8.5 | 55.6% | 4 | LOSS |
LAA@TEX | LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS | 54.1% | 4 | LOSS |
KC@CHW | KC -109 | 54.2% | 4 | WIN |
SD@SEA | DYLAN CEASE OVER 16.5 OUTS | 53.9% | 3 | LOSS |
SD@SEA | UNDER 8.5 | 54.4% | 4 | LOSS |
MIN@TOR | JOE RYAN UNDER 2.5 EARNED RUNS | 54.1% | 4 | LOSS |
SF@MIL | MIL +100 | 54.0% | 6 | LOSS |
TOR@MIA | MIA +1.5 | 62.0% | 6 | WIN |
CHC@LAA | OVER 9.5 | 54.9% | 4 | LOSS |
BOS@NYY | CARLOS RODON UNDER 4.5 HITS ALLOWED | 54.2% | 4 | WIN |
KC@DET | DET -115 | 56.1% | 5 | WIN |
CHC@LAA | LAA +1.5 | 57.6% | 5 | LOSS |