Padres vs. Twins
Prediction, Odds & Props
Aug 29 | MLB AI Picks

Updated: 2025-08-27T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The San Diego Padres (75–59) head to Target Field to take on the Minnesota Twins (60–73) in a pivotal late-season interleague matchup with postseason implications for San Diego and developmental stakes for Minnesota. The Padres look to build on their strong position in the NL West, while the Twins aim to find momentum after a difficult few weeks and a mid-season fire sale.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Aug 29, 2025

Start Time: 8:10 PM EST​

Venue: Target Field​

Twins Record: (60-73)

Padres Record: (75-59)

OPENING ODDS

SD Moneyline: -121

MIN Moneyline: +101

SD Spread: -1.5

MIN Spread: +1.5

Over/Under: 8.5

SD
Betting Trends

  • The Padres sit at 75–59, with a dominant 43–22 home record but a less impressive 32–37 on the road, suggesting caution when betting them away from Petco Park.

MIN
Betting Trends

  • The Twins are 60–73 and in 4th place in the AL Central, having recently sold off veterans at the trade deadline. Their seasonal performance—and likely ATS record—reflects instability and uncertainty.

MATCHUP TRENDS

  • Current odds place the Padres as favorites at around –150, with the total set at 8 runs, signaling expectations of a close but controlled game.

SD vs. MIN
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: F. Tatis over 7.5 Fantasy Score.

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San Diego vs Minnesota Prediction & Odds:
Free MLB Betting Insights for 8/29/25

The August 29, 2025 matchup between the San Diego Padres and the Minnesota Twins at Target Field brings together two teams heading in very different directions, with San Diego carrying postseason aspirations and Minnesota focused more on building for the future. The Padres enter play at 75–59, locked in a tight NL Wild Card race and determined to avoid any slip-ups against opponents below .500, while the Twins sit at 60–73 after a midseason fire sale that effectively signaled their focus had shifted toward development and evaluating younger pieces. For San Diego, the key to their success this year has been balance, as they have combined reliable pitching with a versatile offense that doesn’t lean entirely on the long ball but instead uses contact hitting, smart baserunning, and timely power to manufacture runs. They’ll hand the ball to veteran left-hander Nestor Cortes, who has provided steady innings and a 3.00 ERA in his recent stretch of starts, a presence that gives manager Mike Shildt confidence in a series where dropping games would be costly. Offensively, the Padres are led by a mix of stars and contributors who thrive in situational hitting, and the depth of their order has been crucial in winning close contests, particularly with their bullpen able to protect slim leads when given run support.

For the Twins, the story is quite different, as their 2025 campaign has been marked by inconsistency and a roster reshaped at the deadline, with younger players taking center stage as the front office plans for 2026 and beyond. Starting pitcher Zebby Matthews, who enters with a 3–4 record and a 5.30 ERA, reflects the challenges Minnesota faces: flashes of potential but not yet the consistency needed to contend against lineups as deep as San Diego’s. Their offense has been streaky, capable of producing big innings when Byron Buxton or other veterans get hot, but far too often mired in lulls that leave the pitching staff with little margin for error. Defensively, the Twins have been serviceable but not spectacular, and to hang with San Diego they will need to play clean baseball, limit mistakes, and try to force Cortes into long counts to reach the Padres’ bullpen earlier than planned. From a betting perspective, the Padres enter as road favorites at around –150 with the total set at 8 runs, reflecting expectations of a relatively low-scoring game where San Diego’s pitching depth should keep Minnesota’s bats quiet, but the Padres’ own road struggles (32–37 away from Petco Park) add some uncertainty. The Twins, though underdogs, can look to their home crowd and recent flashes from their younger players as motivation to play spoiler against a club that cannot afford to stumble. Ultimately, this game will hinge on whether San Diego can assert control early behind Cortes and their disciplined offense, or if Minnesota can grind out runs and lean on Matthews to keep the contest close. For the Padres, every game in this stretch is about playoff positioning and proving they can win away from home, while for the Twins, it’s an opportunity to test themselves against a contender and give their fans a glimpse of the fight they hope will define their future.

San Diego Padres MLB Preview

The San Diego Padres head into Target Field on August 29 with a 75–59 record and a clear sense of urgency, knowing that every win is critical in the crowded NL Wild Card race, and facing a struggling Minnesota team presents an opportunity they cannot afford to squander. While San Diego has been dominant at home with a 43–22 mark, their 32–37 road record shows vulnerability, making it imperative that they bring focus and energy into this series against a Twins club looking more toward the future than the present. The Padres will turn to left-hander Nestor Cortes, who has delivered a 3.00 ERA in recent outings and provides the kind of veteran stability they need on the road, particularly against an opponent with limited offensive firepower. Offensively, the Padres thrive on a balanced attack rather than leaning on one or two stars, with a lineup capable of stringing together hits, working counts, and taking advantage of defensive lapses. They have blended timely hitting with aggressive baserunning to create pressure, and this formula has kept them competitive in tight contests where the bullpen, bolstered by midseason acquisitions, has been able to close the door late.

San Diego’s road struggles often come from failing to capitalize on early opportunities, so a key will be striking against Minnesota starter Zebby Matthews before he can settle in, forcing the Twins into their bullpen sooner than they’d prefer. Defensively, the Padres have been sharp, and their ability to limit extra chances has been one of the reasons they remain firmly in the playoff mix despite not always being dominant away from Petco Park. From a betting perspective, they enter as –150 favorites with the total set at eight runs, suggesting expectations of a lower-scoring contest driven by Cortes’ ability to control the game and the Padres’ depth overwhelming a rebuilding Minnesota roster. For manager Mike Shildt, this is the kind of matchup that demands execution rather than flash: disciplined at-bats, clean defense, and reliable bullpen management. If San Diego follows that formula, they not only strengthen their postseason grip but also send a message that they can handle business on the road, something that will be crucial in October. Ultimately, this game is about the Padres asserting themselves as a true contender by proving they can dominate a weaker opponent in an environment where they’ve often been less consistent, and if Cortes delivers as expected while the offense provides timely support, they are well positioned to leave Minneapolis with another critical victory.

The San Diego Padres (75–59) head to Target Field to take on the Minnesota Twins (60–73) in a pivotal late-season interleague matchup with postseason implications for San Diego and developmental stakes for Minnesota. The Padres look to build on their strong position in the NL West, while the Twins aim to find momentum after a difficult few weeks and a mid-season fire sale. San Diego vs Minnesota AI Prediction: Free MLB Betting Insights for Aug 29. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Minnesota Twins MLB Preview

The Minnesota Twins return to Target Field for their August 29 matchup against the Padres sitting at 60–73, and while their playoff hopes have long since faded following a midseason fire sale, this game represents another chance to evaluate young talent and measure themselves against a postseason-caliber opponent. Manager Rocco Baldelli has leaned into a developmental approach, giving extended opportunities to players like starter Zebby Matthews, who enters at 3–4 with a 5.30 ERA and the challenge of facing a deep San Diego lineup. Matthews embodies the broader state of Minnesota’s pitching staff—flashes of promise but still inconsistent, often struggling to navigate lineups multiple times through. Offensively, the Twins have been streaky all year, with Byron Buxton remaining their most dynamic threat when healthy, while veterans like Carlos Correa and Max Kepler provide occasional bursts of production but not the sustained output needed to compete with the division’s top teams. The trade deadline moves signaled a focus on the future, leaving the current roster short on power and reliant on situational hitting to scrape across runs, a strategy that requires flawless execution to succeed against pitchers as savvy as Nestor Cortes.

Defensively, the Twins have been adequate, though lapses at key moments have frequently turned winnable games into losses, and this contest will demand clean execution behind Matthews to limit the Padres’ ability to manufacture runs. From a betting perspective, Minnesota enters as underdogs around +130, a reflection not only of San Diego’s stronger record but also of the Twins’ inconsistent ability to protect home field, where they have hovered below .500. For Minnesota to pull off an upset, they’ll need Matthews to keep the game close through at least five innings, the bullpen to provide steadiness in relief, and the lineup to capitalize on any mistakes from Cortes by stringing together timely hits rather than waiting for the long ball. The Twins’ best chance lies in disrupting San Diego’s rhythm with early pressure and leveraging the energy of the Target Field crowd, which has shown up this year despite the team’s struggles, eager to see signs of progress from a roster in transition. While the postseason is out of reach, this series offers Minnesota an opportunity to play spoiler, instill confidence in its younger players, and build small victories that can carry into next season. For fans and players alike, a win against a contending Padres team would serve as both a morale boost and a reminder that even in a rebuilding year, the Twins are capable of competing with baseball’s better clubs when they execute their fundamentals and seize opportunities.

San Diego vs. Minnesota Prop Picks (AI)

AI algorithm Remi is pouring through mountains of datapoints on each player. In fact, anytime the Padres and Twins play there’s always several intriguing observations to key in on. Not to mention games played at Target Field in Aug rarely follow normal, predictable patterns.
Remi's searched hard and found the best prop for this matchup: F. Tatis over 7.5 Fantasy Score.

San Diego vs. Minnesota Prediction (AI)

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Remi, our AI sports genius, has been pouring over exorbitant amounts of data from every angle between the Padres and Twins and using recursive machine learning and industry leading AI to crunch the data to a single cover probability.

Remi has been most focused on the linear correlation of factor human bettors regularly put on coaching factors between a Padres team going up against a possibly improved Twins team. In reality, the true game analytics appear to reflect a moderate lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI San Diego vs Minnesota picks, computer picks Padres vs Twins, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
MLB 9/26 DET@BOS UNLOCK THIS PICK 5 EXECUTIVE Locked EXECUTIVE
MLB 9/26 BAL@NYY UNLOCK THIS PICK 4 INTEL Locked INTEL
MLB 9/26 ARI@SD UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
MLB 9/26 NYM@MIA UNLOCK THIS PICK 1 INTEL Locked INTEL
MLB 9/26 NYM@MIA GET FREE PICK NOW 1
MLB 9/26 COL@SF UNLOCK THIS PICK 0 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

Padres Betting Trends

The Padres sit at 75–59, with a dominant 43–22 home record but a less impressive 32–37 on the road, suggesting caution when betting them away from Petco Park.

Twins Betting Trends

The Twins are 60–73 and in 4th place in the AL Central, having recently sold off veterans at the trade deadline. Their seasonal performance—and likely ATS record—reflects instability and uncertainty.

Padres vs. Twins Matchup Trends

Current odds place the Padres as favorites at around –150, with the total set at 8 runs, signaling expectations of a close but controlled game.

San Diego vs. Minnesota Game Info

San Diego vs Minnesota starts on August 29, 2025 at 8:10 PM EST.

Spread: Minnesota +1.5
Moneyline: San Diego -121, Minnesota +101
Over/Under: 8.5

San Diego: (75-59)  |  Minnesota: (60-73)

Remi's searched hard and found the best prop for this matchup: F. Tatis over 7.5 Fantasy Score.. Prices move—always shop for the best number.

Current odds place the Padres as favorites at around –150, with the total set at 8 runs, signaling expectations of a close but controlled game.

SD trend: The Padres sit at 75–59, with a dominant 43–22 home record but a less impressive 32–37 on the road, suggesting caution when betting them away from Petco Park.

MIN trend: The Twins are 60–73 and in 4th place in the AL Central, having recently sold off veterans at the trade deadline. Their seasonal performance—and likely ATS record—reflects instability and uncertainty.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

San Diego vs. Minnesota Odds

Remi is pouring through mountains of data on each team. In fact, anytime the San Diego vs Minnesota trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme travel distance seemingly never follow normal, predictable patterns.

San Diego vs Minnesota Opening Odds

SD Moneyline: -121
MIN Moneyline: +101
SD Spread: -1.5
MIN Spread: +1.5
Over/Under: 8.5

San Diego vs Minnesota Live Odds

Games PTS ML SPR O/U
Sep 27, 2025 1:06PM EDT
Baltimore Orioles
New York Yankees
9/27/25 1:06PM
Orioles
Yankees
+194
-235
+1.5 (-105)
-1.5 (-114)
O 8.5 (-122)
U 8.5 (+100)
Sep 27, 2025 2:21PM EDT
St Louis Cardinals
Chicago Cubs
9/27/25 2:21PM
Cardinals
Cubs
 
-168
 
-1.5 (+118)
O 9 (-122)
U 9 (+100)
Sep 27, 2025 3:09PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/27/25 3:09PM
Rays
Blue Jays
+132
-156
+1.5 (-154)
-1.5 (+128)
O 8.5 (-106)
U 8.5 (-114)
Sep 27, 2025 4:06PM EDT
Chicago White Sox
Washington Nationals
9/27/25 4:06PM
White Sox
Nationals
+102
-120
-1.5 (+162)
+1.5 (-196)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 4:06PM EDT
Colorado Rockies
San Francisco Giants
9/27/25 4:06PM
Rockies
Giants
+198
-240
+1.5 (-110)
-1.5 (-110)
O 8 (-108)
U 8 (-112)
Sep 27, 2025 4:11PM EDT
New York Mets
Miami Marlins
9/27/25 4:11PM
Mets
Marlins
-124
+106
-1.5 (+130)
+1.5 (-156)
O 8.5 (-112)
U 8.5 (-108)
Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
+172
-205
+1.5 (-118)
-1.5 (+100)
O 8.5 (-115)
U 8.5 (-105)
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
+128
-152
+1.5 (-178)
-1.5 (+146)
O 7.5 (-120)
U 7.5 (-102)
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
+136
-162
+1.5 (-150)
-1.5 (+125)
O 8 (-105)
U 8 (-115)
Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
+138
-164
+1.5 (-164)
-1.5 (+136)
O 7.5 (-110)
U 7.5 (-110)
Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
+120
-142
+1.5 (-182)
-1.5 (+150)
O 7.5 (-118)
U 7.5 (-104)
Sep 27, 2025 9:39PM EDT
Houston Astros
Los Angeles Angels
9/27/25 9:39PM
Astros
Angels
-162
+136
-1.5 (+100)
+1.5 (-120)
O 9 (+100)
U 9 (-122)
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
+102
-120
+1.5 (-215)
-1.5 (+180)
O 7.5 (-110)
U 7.5 (-110)
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
+100
-118
-1.5 (+152)
+1.5 (-184)
O 10 (-110)
U 10 (-110)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers San Diego Padres vs. Minnesota Twins on August 29, 2025 at Target Field.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS
CIN@ARI KEBRYAN HAYES STRIKEOUTS UNDER 0.5 56.2% 6 WIN
LAD@SD SD +110 50.9% 6 WIN