Pirates vs Cardinals Prediction — AI Finds CAN'T MISS MLB Lines & Props (Aug 28)
Updated: 2025-08-26T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The Pittsburgh Pirates (56–74) wrap up a challenging season in St. Louis, facing a Cardinals club (65–68) still chasing relevance in the NL Central standings. It’s a late-August clash with postseason pressure for St. Louis and developmental spotlight for Pittsburgh.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Aug 28, 2025
Start Time: 2:15 PM EST
Venue: Busch Stadium
Cardinals Record: (65-69)
Pirates Record: (59-75)
OPENING ODDS
PIT Moneyline: +105
STL Moneyline: -125
PIT Spread: +1.5
STL Spread: -1.5
Over/Under: 8.5
PIT
Betting Trends
- Pittsburgh sits at the bottom of the division and shows an inconsistent betting pattern, often failing to meet expectations—reflected by a below-.500 ATS record.
STL
Betting Trends
- Pittsburgh sits at the bottom of the division and shows an inconsistent betting pattern, often failing to meet expectations—reflected by a below-.500 ATS record.
MATCHUP TRENDS
- Interestingly, the Cardinals excel in one-run situations, going 21–18 in one-run games, highlighting their knack for tight, late-game execution even when their overall record is sub-.500.
PIT vs. STL
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: N. Gorman over 0.5 Total Bases.
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Pittsburgh vs St. Louis Prediction & Odds:
Free MLB Betting Insights for 8/28/25
By contrast, the Cardinals, though hovering just under .500, approach the matchup with urgency, recognizing that their 65–68 mark still leaves them within striking distance of a Wild Card berth if they can string together wins in September. St. Louis has relied on the stabilizing presence of Sonny Gray in the rotation and Andre Pallante’s effectiveness in generating ground balls, while the bullpen has shown resilience in high-leverage situations, allowing them to excel in close contests, evidenced by their 21–18 record in one-run games. Offensively, the Cardinals benefit from the steady defense and emerging bat of Masyn Winn, the power and patience of Willson Contreras, and flashes from young role players who have provided depth throughout the lineup, creating enough balance to remain competitive even without a dominant offensive centerpiece. From a betting perspective, the contrast is stark: Pittsburgh’s volatile and often disappointing ATS record underscores its inconsistency, while St. Louis has been more reliable, posting a 34–32 mark against the spread on the road and carrying a reputation for grinding out wins in lower-scoring affairs. For the Pirates, this matchup is about development, culture, and pride—finding ways to test their youth against a disciplined divisional foe and instilling confidence for the future, while for the Cardinals it is about execution, urgency, and the pursuit of meaningful games in September that could determine whether they remain relevant in the playoff chase. Ultimately, this game embodies the dual nature of late-season baseball: one team playing for tomorrow, the other clinging to the hope that today still matters in the race toward October.
Look at the dub, right thurr.#RaiseIt 🏴☠️ pic.twitter.com/qz3wQesO6P
— Pittsburgh Pirates (@Pirates) August 28, 2025
Pittsburgh Pirates MLB Preview
The Pittsburgh Pirates arrive in St. Louis for their August 28, 2025 matchup against the Cardinals with a 56–74 record that reflects a season of frustration and rebuilding, yet beneath the struggles lies a story of growth, individual milestones, and glimpses of a brighter future that fans hope will eventually lift the franchise back to contention. The most significant storyline for Pittsburgh has been the emergence of Paul Skenes, who has quickly established himself as one of the most electric young pitchers in baseball, earning his second straight All-Star selection thanks to his overpowering fastball, command, and strikeout dominance, and his starts have become appointment viewing even during a tough season. Manager Derek Shelton has leaned heavily on Skenes to anchor a rotation otherwise riddled with inconsistency, as veterans and younger arms alike have failed to find steady footing, often leaving the bullpen overworked and exposed in late-inning situations that have cost the team close games. Offensively, the Pirates have relied on a mix of aging veterans and developing pieces, with Andrew McCutchen continuing to provide leadership and moments of inspiration, including surpassing Roberto Clemente on the franchise’s all-time home run list earlier this season, while Bryan Reynolds has remained the team’s most reliable bat, offering consistent production in the heart of the order. Contributions from younger players such as Jared Triolo have offered encouragement, and the flashes of offensive growth from the likes of Henry Davis provide further optimism that the team is building a foundation for future success.
Still, the offense remains streaky, prone to long stretches where situational hitting evaporates, and road contests against disciplined clubs like the Cardinals often expose those weaknesses. Defensively, the Pirates have shown competence in stretches, with Reynolds providing stability in the outfield and Ke’Bryan Hayes flashing Gold Glove caliber play at third base, but errors at inopportune moments have been a persistent issue. From a betting standpoint, Pittsburgh has been an unreliable team against the spread, reflecting the inconsistency of a roster that can surprise with competitive performances one night and collapse the next. For the Pirates, this matchup against St. Louis is less about altering the standings and more about continuing to evaluate young talent in high-pressure environments, instilling resilience in their clubhouse, and giving fans reason to believe that patience will pay off. Every inning Skenes throws, every at-bat a young hitter takes, and every defensive chance converted or missed becomes a data point in assessing who will form the nucleus of the next competitive Pirates team. Facing a Cardinals squad with playoff hopes still alive ensures that the challenge will be formidable, but it also provides the kind of test that Pittsburgh’s front office and coaching staff want for their players, a benchmark against which development and competitiveness can be measured. While the Pirates enter as clear underdogs, a spirited performance in St. Louis would serve as validation of incremental progress and offer a reminder that while 2025 may not yield wins in the standings, it can still produce meaningful steps toward the future.

Credit: USA TODAY/IMAGN
St. Louis Cardinals MLB Preview
The St. Louis Cardinals take the field at Busch Stadium on August 28, 2025 against the Pittsburgh Pirates carrying a 65–68 record that reflects a turbulent but still hopeful season, one where consistency has been elusive but postseason dreams remain alive if they can string together a strong September run, and this matchup against a last-place rival represents both an opportunity and a test of their ability to stay composed under pressure. The Cardinals have spent much of the year fighting to balance veteran leadership with the integration of younger players, and while their offense has lacked the explosiveness of past seasons, they have found ways to stay competitive through situational execution and late-inning grit, highlighted by a 21–18 record in one-run games that demonstrates their ability to win tight contests. Sonny Gray has been the staff ace, giving St. Louis quality starts and stability when the rotation needed it most, while Andre Pallante’s groundball-heavy approach has complemented Gray by forcing weak contact and keeping the defense engaged behind him. The bullpen, though tested heavily, has held up in big spots often enough to keep the Cardinals relevant, with relievers showing poise when tasked with protecting slim leads in divisional matchups. At the plate, Willson Contreras has delivered with his combination of power and patience, Masyn Winn has cemented himself as a defensive anchor at shortstop while steadily improving his offensive game, and contributions from role players have kept the lineup serviceable even when stars have slumped.
The Cardinals’ approach relies on grinding out at-bats, moving runners, and capitalizing on mistakes, a formula that has allowed them to compete despite lacking the firepower of teams at the top of the league. Defensively, the club continues to emphasize fundamentals and efficiency, traits that are especially important in a division where games are often decided by small margins. From a betting standpoint, St. Louis has been slightly more reliable than their overall record suggests, with a 34–32 ATS mark on the road and a solid track record at home, making them a team that often delivers value in close spreads and underscoring their competitive character. Manager Oliver Marmol continues to stress the importance of discipline and detail as the team enters the final month of the season, knowing that every game carries amplified significance in their quest to sneak into Wild Card contention. Hosting the Pirates offers a chance not only to gain ground but also to sharpen the kind of habits—clean defense, bullpen execution, and situational hitting—that will be essential if they are to make a serious push. For the Cardinals and their fans, this game is more than just another divisional contest; it is a reminder of the franchise’s standard, the pride that comes with wearing the uniform, and the hope that even a season filled with ups and downs can still end with meaningful baseball in October if they remain resilient and seize the opportunities in front of them.
Seven strikeouts over seven innings from Sonny pic.twitter.com/zCWFvP5G0O
— St. Louis Cardinals (@Cardinals) August 28, 2025
Pittsburgh vs. St. Louis Prop Picks (AI)
Pittsburgh vs. St. Louis Prediction (AI)

Remi, our AI sports wizard, has been pouring over millions of data from every angle between the Pirates and Cardinals and using recursive machine learning and cutting-edge AI to analyze the data to a single cover probability.
Oddly enough, we’ve seen the AI has been most keyed in on the trending weight emotional bettors often put on St. Louis’s strength factors between a Pirates team going up against a possibly strong Cardinals team. It appears the true game analytics might reflect a strong lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.
Below is our current AI Pittsburgh vs St. Louis picks, computer picks Pirates vs Cardinals, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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MLB | 10/20 | SEA@TOR | UNLOCK THIS PICK | 2 |
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MLB | 10/20 | SEA@TOR | UNLOCK THIS PICK | 0 |
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.
Pirates Betting Trends
Pittsburgh sits at the bottom of the division and shows an inconsistent betting pattern, often failing to meet expectations—reflected by a below-.500 ATS record.
Cardinals Betting Trends
Pittsburgh sits at the bottom of the division and shows an inconsistent betting pattern, often failing to meet expectations—reflected by a below-.500 ATS record.
Pirates vs. Cardinals Matchup Trends
Interestingly, the Cardinals excel in one-run situations, going 21–18 in one-run games, highlighting their knack for tight, late-game execution even when their overall record is sub-.500.
Pittsburgh vs. St. Louis Game Info
What time does Pittsburgh vs St. Louis start on August 28, 2025?
Pittsburgh vs St. Louis starts on August 28, 2025 at 2:15 PM EST.
Where is Pittsburgh vs St. Louis being played?
Venue: Busch Stadium.
What are the opening odds for Pittsburgh vs St. Louis?
Spread: St. Louis -1.5
Moneyline: Pittsburgh +105, St. Louis -125
Over/Under: 8.5
What are the records for Pittsburgh vs St. Louis?
Pittsburgh: (59-75) | St. Louis: (65-69)
What is the AI best bet for Pittsburgh vs St. Louis?
Remi's searched hard and found the best prop for this matchup: N. Gorman over 0.5 Total Bases.. Prices move—always shop for the best number.
What are Pittsburgh vs St. Louis trending bets?
Interestingly, the Cardinals excel in one-run situations, going 21–18 in one-run games, highlighting their knack for tight, late-game execution even when their overall record is sub-.500.
What are Pittsburgh trending bets?
PIT trend: Pittsburgh sits at the bottom of the division and shows an inconsistent betting pattern, often failing to meet expectations—reflected by a below-.500 ATS record.
What are St. Louis trending bets?
STL trend: Pittsburgh sits at the bottom of the division and shows an inconsistent betting pattern, often failing to meet expectations—reflected by a below-.500 ATS record.
Where can I find AI Picks for Pittsburgh vs St. Louis?
See our latest MLB picks and odds pages for 2025 to compare prices before you bet.
Pittsburgh vs. St. Louis Odds
Remi is pouring through loads of stats on each line. In fact, anytime the Pittsburgh vs St. Louis trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme temps seemingly never follow normal, predictable patterns.
Pittsburgh vs St. Louis Opening Odds
PIT Moneyline:
+105 STL Moneyline: -125
PIT Spread: +1.5
STL Spread: -1.5
Over/Under: 8.5
Pittsburgh vs St. Louis Live Odds
Games | PTS | ML | SPR | O/U | |
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Oct 24, 2025 9:08PM EDT
Los Angeles Dodgers
Toronto Blue Jays
10/24/25 9:08PM
Dodgers
Blue Jays
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–
–
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-140
+127
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-1.5 (+124)
+1.5 (-140)
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O 7.5 (+107)
U 7.5 (-123)
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MLB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Pittsburgh Pirates vs. St. Louis Cardinals on August 28, 2025 at Busch Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
TOR@SEA | OVER 7 | 54.9% | 3 | WIN |
LAD@MIL | UNDER 7.5 | 56.6% | 6 | WIN |
TOR@NYY | OVER 8 | 54.9% | 4 | WIN |
TOR@NYY | CARLOS RODON OVER 1.5 TOTAL WALKS ALLOWED | 53.3% | 3 | WIN |
NYY@TOR | OVER 7.5 | 54.8% | 2 | WIN |
LAD@PHI | OVER 7 | 53.8% | 3 | WIN |
SD@CHC | CHC -109 | 53.8% | 3 | WIN |
SD@CHC | OVER 7.5 | 54.5% | 4 | LOSS |
SD@CHC | CHC -111 | 54.8% | 4 | LOSS |
CIN@LAD | SHOHEI OHTANI OVER 1.5 BASES | 53.5% | 3 | WIN |
BOS@NYY | OVER 7 | 53.8% | 3 | LOSS |
CIN@LAD | ELLY DE LA CRUZ OVER 0.5 BASES | 54.4% | 4 | LOSS |
ARI@SD | SD -131 | 57.3% | 4 | WIN |
DET@BOS | BOS -115 | 56.4% | 5 | WIN |
NYM@CHC | NYM -110 | 54.1% | 3 | WIN |
HOU@ATH | ATH +118 | 50.8% | 4 | WIN |
NYM@CHC | OVER 7 | 54.5% | 3 | WIN |
STL@SF | OVER 7.5 | 55.9% | 5 | LOSS |
KC@LAA | TYLER TOLBERT UNDER 1.5 BASES | 54.4% | 4 | WIN |
MIL@SD | UNDER 9 | 54.7% | 4 | WIN |
MIA@PHI | KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS | 53.3% | 3 | WIN |
WAS@NYM | OVER 8.5 | 56.1% | 6 | LOSS |
LAA@COL | COL +108 | 50.5% | 3 | WIN |
TOR@KC | UNDER 9 | 54.7% | 4 | LOSS |
SEA@KC | KC +1.5 | 62.3% | 5 | LOSS |
NYY@MIN | OVER 9 | 55.1% | 4 | WIN |
MIA@COL | OVER 10.5 | 55.0% | 4 | WIN |
MIA@COL | AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS | 54.3% | 4 | WIN |
SEA@KC | BOBBY WITT UNDER 0.5 SINGLES | 54.4% | 4 | LOSS |
PHI@LAD | LAD -113 | 54.7% | 4 | LOSS |
NYY@BOS | OVER 7.5 | 54.3% | 3 | WIN |
KC@PHI | PHI -130 | 58.3% | 4 | WIN |
LAD@SF | OVER 7.5 | 54.7% | 4 | LOSS |
NYM@PHI | PHI -122 | 55.6% | 4 | WIN |
KC@CLE | KC -104 | 52.0% | 3 | WIN |
CIN@SD | JAKE CRONEWORTH OVER 0.5 HITS | 53.1% | 3 | WIN |
WAS@MIA | MIA -123 | 55.2% | 4 | LOSS |
LAA@KC | UNDER 9.5 | 54.9% | 3 | WIN |
TEX@ARI | UNDER 9 | 54.2% | 4 | WIN |
SF@COL | UNDER 11.5 | 56.4% | 6 | LOSS |
SF@COL | RAFAEL DEVERS OVER 1.5 BASES | 56.1% | 6 | WIN |
MIA@WAS | WAS -110 | 54.4% | 4 | WIN |
NYM@DET | OVER 8.5 | 54.5% | 4 | WIN |
TEX@ARI | UNDER 9.5 | 56.4% | 6 | WIN |
TEX@ARI | ALEJANDRO OSUNA UNDER 1.5 BASES | 54.1% | 4 | LOSS |
ATL@CHC | CHC -116 | 55.1% | 3 | WIN |
PHI@MIL | OVER 8.5 | 55.0% | 3 | WIN |
ARI@LAD | SHOHEI OHTANI OVER 2.5 BASES | 54.2% | 4 | WIN |
SEA@CLE | CLE +1.5 | 57.2% | 3 | WIN |
CHC@SF | CHC -105 | 54.1% | 4 | LOSS |
NYY@CHW | RYAN MCMAHON OVER 0.5 BASES | 54.1% | 4 | WIN |