Rays vs. Guardians
Prediction, Odds & Props
Aug 25 | MLB AI Picks
Updated: 2025-08-23T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The Tampa Bay Rays visit Progressive Field on August 25, 2025, facing off against the Cleveland Guardians in a pivotal interleague matchup. Both teams hover around .500, making this game a potential momentum-changer in their push toward playoff positioning.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Aug 25, 2025
Start Time: 6:40 PM EST
Venue: Progressive Field
Guardians Record: (64-65)
Rays Record: (63-67)
OPENING ODDS
TB Moneyline: +128
CLE Moneyline: -153
TB Spread: +1.5
CLE Spread: -1.5
Over/Under: 8
TB
Betting Trends
- Favored at −143 moneyline and −1.5 on the run line, with a 58.8% implied win probability.
CLE
Betting Trends
- Favored at −143 moneyline and −1.5 on the run line, with a 58.8% implied win probability.
MATCHUP TRENDS
- Guardians have been strong when favored, winning 60% of such matchups—while the Rays win underdog games about 39% of the time—a substantial edge for Cleveland in similar roles.
TB vs. CLE
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: J. Lowe over 5.5 Fantasy Score.
LIVE MLB ODDS
MLB ODDS COMPARISON
WANT MORE AI PICKS?
VS. SPREAD
310-223
NET UNITS
(INCL VIG)
+416.9
NET PROFIT
(INCL VIG)
$100/UNIT
$41,686
VS. SPREAD
1559-1329
NET UNITS
(INCL VIG)
+395.7
NET PROFIT
(INCL VIG)
$100/UNIT
$39,572
AI SPORTS PICK PRODUCTS
Create a Free Account

Remi Finds New Picks

Remi Works 24/7
Remi uses this probability to assign units to each pick.
Get Remi's AI Picks
Get Remi’s Top AI Sports Picks sent direct to your inbox.
Hedge Meaning in Betting | 4 Obvious Times to Hedge
Learn about hedge betting to manage risk and secure profits. Understand...
What is a Push in Betting? | 3 Ways To Use To Your Advantage
Understand what a push in betting means, how it happens in...
What Does the + and – Mean in Sports Betting? | 5 Easy Tips
Learn the basics of sports betting odds, what the plus (+)...
Tampa Bay vs Cleveland Prediction & Odds:
Free MLB Betting Insights for 8/25/25
These injuries may push both managers—Stephen Vogt for Cleveland and Kevin Cash for Tampa Bay—into creative lineup adjustments, defensive shuffles, and earlier bullpen use. Tampa Bay has shown resilience all season, especially with a pitching staff stretched thin by the loss of Shane McClanahan and others, but their offense has also demonstrated a knack for scraping together runs through contact hitting, aggressive base running, and situational execution. Cleveland, meanwhile, relies more on disciplined at-bats, high-contact hitters, and timely power, especially from their middle infielders and corner bats who thrive in home splits. The Guardians have a slight edge in terms of familiarity and rest at home, but Tampa’s unpredictability, paired with a young pitcher few Guardians have seen, adds an element of volatility that could work in the Rays’ favor. Both teams know the postseason is slipping further away with each series loss, so urgency will be high, particularly in tight moments where bullpen matchups and fielding execution could decide the game. If Seymour can navigate the Cleveland lineup twice through without damage and Bibee avoids the long ball—a weakness in his recent outings—this could shape up to be a pitcher’s duel with late scoring, particularly if either bullpen cracks under pressure. With so much on the line and the margins this thin, the game likely comes down to one or two pivotal at-bats, and with both teams struggling for consistency, the matchup remains as wide open as the odds suggest, promising a tightly fought, strategic battle from first pitch to final out.
Flying off w/ the series @budweiserUSA | #RaysUp
— Tampa Bay Rays (@RaysBaseball) August 24, 2025
Tampa Bay Rays MLB Preview
The Tampa Bay Rays enter Monday’s matchup against the Cleveland Guardians as underdogs both in the standings and in the betting markets, sitting at 63–67 on the season and priced around +121 on the moneyline, yet they continue to embody the kind of gritty, strategic baseball that has made them a perennial threat even in years where injuries and roster turnover have challenged consistency. Tampa’s pitching staff has been particularly strained this year, with ace Shane McClanahan out for the season and others in and out of the rotation, which has opened the door for young arms like Ian Seymour, a 25-year-old lefty who will take the mound for just his second big-league start. Seymour impressed in his debut, showing poise and command over his three-pitch mix, including a fastball in the low 90s and a tight slider that induced weak contact, and the Guardians’ unfamiliarity with him could work in Tampa’s favor as they look to steal a road win with a pitcher who presents an unknown variable. The Rays are still down several regulars, with Ha-Seong Kim and Taylor Walls both listed day-to-day, while outfield depth has taken a hit with injuries to Jonny DeLuca and Jonathan Aranda, forcing manager Kevin Cash to shuffle his lineup card and rely more heavily on platoons, bench bats, and speed to manufacture offense.
That has become the Rays’ calling card—smart situational hitting, aggressive base running, and a bullpen that remains quietly effective, even if stretched at times due to short starts and close games. Tampa Bay’s ability to turn over its lineup with productive at-bats will be key, especially if they can force Tanner Bibee into high pitch counts early—Bibee, though durable, has been prone to allowing traffic on the bases and occasionally lets innings spiral when he loses fastball command. The Rays will likely look to test Cleveland’s defense with bunts, stolen base attempts, and hit-and-run plays, and if they can scratch out a couple of runs early, they’ll be able to lean on their bullpen in the later innings. Even with diminished firepower, Tampa has remained competitive in games expected to be low scoring, as evidenced by the tight betting total of 8 runs for this contest. What gives them an edge is unpredictability—where other teams live and die by the home run, the Rays thrive in chaos, creating offense through hustle, defense, and depth. That approach, combined with the element of surprise that Seymour brings, makes them a dangerous team to overlook. While Cleveland may have the slight advantage on paper with home-field support and a more seasoned starter, Tampa Bay’s ability to capitalize on opponent mistakes, grind out at-bats, and shorten the game with a savvy bullpen gives them a real chance to flip the script in a game that oddsmakers consider close. If Seymour can get through the Guardians’ lineup twice and hand over a lead or tie to the relievers, the Rays may be poised to snatch a critical late-August win and keep their postseason hopes flickering.

Credit: USA TODAY/IMAGN
Cleveland Guardians MLB Preview
The Cleveland Guardians return home to Progressive Field on Monday, August 25, 2025, looking to regain their footing against a scrappy Tampa Bay Rays team that has historically thrived in tight, low-scoring matchups, but the Guardians will enter this game as slight favorites with a moneyline around –143 and a run line of –1.5, reflecting both home-field advantage and the steadiness of right-hander Tanner Bibee, who takes the mound with a 9–9 record, 4.62 ERA, and 129 strikeouts over the course of more than 140 innings this season. Bibee has been a pillar of durability for Cleveland’s rotation, even if his ERA doesn’t suggest dominance—he consistently delivers five or six innings of competitive baseball and has shown the ability to pitch out of jams with his rising fastball and biting slider, two pitches that could prove effective against a Tampa Bay lineup that lacks key contributors due to injuries. Cleveland, sitting just below .500 at 64–65, knows it must capitalize on winnable matchups at home if it hopes to keep pace in the AL Wild Card race, and this contest offers a prime opportunity to take advantage of a young, inexperienced Rays starter in Ian Seymour, a lefty making only his second big-league start and still adjusting to the pace and pressure of major league competition.
Offensively, the Guardians have dealt with their own issues, including injuries to Paul Sewald and Lane Thomas, both listed as questionable, which may impact their bullpen structure and outfield defense, but their everyday lineup remains largely intact and capable of stringing together quality at-bats against lesser-known arms. Manager Stephen Vogt will likely lean on his team’s situational hitting, putting runners in motion and applying pressure early to rattle Seymour and potentially chase him by the middle innings, which would expose Tampa Bay’s bullpen to heavier use after a long series. Bibee’s key to success will be avoiding walks and minimizing early pitch counts so he can bridge the game to Cleveland’s high-leverage arms, especially if Sewald is unavailable and the late innings fall on secondary relievers. The Guardians will need timely hitting from their middle-of-the-order bats—those who have succeeded in home splits all season—to jump-start the offense and prevent the Rays from playing the kind of grind-it-out baseball that keeps games close into the seventh and eighth innings. Even without significant power output, Cleveland thrives on exploiting small opportunities, drawing walks, moving runners, and staying within their approach, especially at home where they’ve played competitive baseball all year. If Bibee can avoid early damage and maintain a lead, and if the Guardians can make life difficult for Seymour with aggressive base running and disciplined at-bats, they are in a strong position to take the opener of this series and build momentum down the stretch. With so little margin for error in the standings and the postseason push intensifying, this game offers Cleveland a clear path to victory—control the tempo, win the middle innings, and let their veteran poise and home crowd energy guide them through the late stages of a winnable contest.
Home soon.#GuardsBall pic.twitter.com/DNGn6anH0a
— Cleveland Guardians (@CleGuardians) August 24, 2025
Tampa Bay vs. Cleveland Prop Picks (AI)
Tampa Bay vs. Cleveland Prediction (AI)

Remi, our AI sports wizard, has been pouring over exorbitant amounts of data from every simulation between the Rays and Guardians and using recursive machine learning and kick-ass AI to examine the data to a single cover probability.
Interestingly enough, the data has been most keyed in on the trending factor knucklehead sportsbettors often put on coaching factors between a Rays team going up against a possibly deflated Guardians team. Trends look to say the true game analytics might reflect a strong lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.
Below is our current AI Tampa Bay vs Cleveland picks, computer picks Rays vs Guardians, best bets, model edges, confidence ratings.
![]() |
DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
---|---|---|---|---|---|---|
ACTIVE PICKS LOCKED - SEE NOW |
These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.
Rays Betting Trends
Favored at −143 moneyline and −1.5 on the run line, with a 58.8% implied win probability.
Guardians Betting Trends
Favored at −143 moneyline and −1.5 on the run line, with a 58.8% implied win probability.
Rays vs. Guardians Matchup Trends
Guardians have been strong when favored, winning 60% of such matchups—while the Rays win underdog games about 39% of the time—a substantial edge for Cleveland in similar roles.
Tampa Bay vs. Cleveland Game Info
What time does Tampa Bay vs Cleveland start on August 25, 2025?
Tampa Bay vs Cleveland starts on August 25, 2025 at 6:40 PM EST.
Where is Tampa Bay vs Cleveland being played?
Venue: Progressive Field.
What are the opening odds for Tampa Bay vs Cleveland?
Spread: Cleveland -1.5
Moneyline: Tampa Bay +128, Cleveland -153
Over/Under: 8
What are the records for Tampa Bay vs Cleveland?
Tampa Bay: (63-67) | Cleveland: (64-65)
What is the AI best bet for Tampa Bay vs Cleveland?
Remi's searched hard and found the best prop for this matchup: J. Lowe over 5.5 Fantasy Score.. Prices move—always shop for the best number.
What are Tampa Bay vs Cleveland trending bets?
Guardians have been strong when favored, winning 60% of such matchups—while the Rays win underdog games about 39% of the time—a substantial edge for Cleveland in similar roles.
What are Tampa Bay trending bets?
TB trend: Favored at −143 moneyline and −1.5 on the run line, with a 58.8% implied win probability.
What are Cleveland trending bets?
CLE trend: Favored at −143 moneyline and −1.5 on the run line, with a 58.8% implied win probability.
Where can I find AI Picks for Tampa Bay vs Cleveland?
See our latest MLB picks and odds pages for 2025 to compare prices before you bet.
Tampa Bay vs. Cleveland Odds
Remi is pouring through loads of stats on each team. In fact, anytime the Tampa Bay vs Cleveland trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme altitude seemingly never follow normal, predictable patterns.
Tampa Bay vs Cleveland Opening Odds
TB Moneyline:
+128 CLE Moneyline: -153
TB Spread: +1.5
CLE Spread: -1.5
Over/Under: 8
Tampa Bay vs Cleveland Live Odds
Games | PTS | ML | SPR | O/U | |
---|---|---|---|---|---|
Sep 30, 2025 2:30PM EDT
Boston Red Sox
New York Yankees
9/30/25 2:30PM
Red Sox
Yankees
|
–
–
|
+107
-130
|
pk
pk
|
|
|
Sep 30, 2025 2:30PM EDT
Detroit Tigers
Cleveland Guardians
9/30/25 2:30PM
Tigers
Guardians
|
–
–
|
-164
+138
|
-1.5 (+112)
+1.5 (-134)
|
O 6.5 (-106)
U 6.5 (-114)
|
|
Sep 30, 2025 2:30PM EDT
San Diego Padres
Chicago Cubs
9/30/25 2:30PM
Padres
Cubs
|
–
–
|
+102
-120
|
pk
pk
|
|
|
Sep 30, 2025 6:09PM EDT
Boston Red Sox
New York Yankees
9/30/25 6:09PM
Red Sox
Yankees
|
–
–
|
+112
-132
|
+1.5 (-200)
-1.5 (+164)
|
O 7 (-115)
U 7 (-105)
|
|
Sep 30, 2025 9:08PM EDT
Cincinnati Reds
Los Angeles Dodgers
9/30/25 9:08PM
Reds
Dodgers
|
–
–
|
+142
-168
|
+1.5 (-166)
-1.5 (+138)
|
O 7.5 (+100)
U 7.5 (-122)
|
MLB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Tampa Bay Rays vs. Cleveland Guardians on August 25, 2025 at Progressive Field.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.
![]() |
LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
ARI@SD | SD -131 | 57.3% | 4 | WIN |
DET@BOS | BOS -115 | 56.4% | 5 | WIN |
NYM@CHC | NYM -110 | 54.1% | 3 | WIN |
HOU@ATH | ATH +118 | 50.8% | 4 | WIN |
NYM@CHC | OVER 7 | 54.5% | 3 | WIN |
STL@SF | OVER 7.5 | 55.9% | 5 | LOSS |
KC@LAA | TYLER TOLBERT UNDER 1.5 BASES | 54.4% | 4 | WIN |
MIL@SD | UNDER 9 | 54.7% | 4 | WIN |
MIA@PHI | KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS | 53.3% | 3 | WIN |
WAS@NYM | OVER 8.5 | 56.1% | 6 | LOSS |
LAA@COL | COL +108 | 50.5% | 3 | WIN |
TOR@KC | UNDER 9 | 54.7% | 4 | LOSS |
SEA@KC | KC +1.5 | 62.3% | 5 | LOSS |
NYY@MIN | OVER 9 | 55.1% | 4 | WIN |
MIA@COL | OVER 10.5 | 55.0% | 4 | WIN |
MIA@COL | AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS | 54.3% | 4 | WIN |
SEA@KC | BOBBY WITT UNDER 0.5 SINGLES | 54.4% | 4 | LOSS |
PHI@LAD | LAD -113 | 54.7% | 4 | LOSS |
NYY@BOS | OVER 7.5 | 54.3% | 3 | WIN |
KC@PHI | PHI -130 | 58.3% | 4 | WIN |
LAD@SF | OVER 7.5 | 54.7% | 4 | LOSS |
NYM@PHI | PHI -122 | 55.6% | 4 | WIN |
KC@CLE | KC -104 | 52.0% | 3 | WIN |
CIN@SD | JAKE CRONEWORTH OVER 0.5 HITS | 53.1% | 3 | WIN |
WAS@MIA | MIA -123 | 55.2% | 4 | LOSS |
LAA@KC | UNDER 9.5 | 54.9% | 3 | WIN |
TEX@ARI | UNDER 9 | 54.2% | 4 | WIN |
SF@COL | UNDER 11.5 | 56.4% | 6 | LOSS |
SF@COL | RAFAEL DEVERS OVER 1.5 BASES | 56.1% | 6 | WIN |
MIA@WAS | WAS -110 | 54.4% | 4 | WIN |
NYM@DET | OVER 8.5 | 54.5% | 4 | WIN |
TEX@ARI | UNDER 9.5 | 56.4% | 6 | WIN |
TEX@ARI | ALEJANDRO OSUNA UNDER 1.5 BASES | 54.1% | 4 | LOSS |
ATL@CHC | CHC -116 | 55.1% | 3 | WIN |
PHI@MIL | OVER 8.5 | 55.0% | 3 | WIN |
ARI@LAD | SHOHEI OHTANI OVER 2.5 BASES | 54.2% | 4 | WIN |
SEA@CLE | CLE +1.5 | 57.2% | 3 | WIN |
CHC@SF | CHC -105 | 54.1% | 4 | LOSS |
NYY@CHW | RYAN MCMAHON OVER 0.5 BASES | 54.1% | 4 | WIN |
PHI@NYM | OVER 8.5 | 55.6% | 4 | LOSS |
LAA@TEX | LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS | 54.1% | 4 | LOSS |
KC@CHW | KC -109 | 54.2% | 4 | WIN |
SD@SEA | DYLAN CEASE OVER 16.5 OUTS | 53.9% | 3 | LOSS |
SD@SEA | UNDER 8.5 | 54.4% | 4 | LOSS |
MIN@TOR | JOE RYAN UNDER 2.5 EARNED RUNS | 54.1% | 4 | LOSS |
SF@MIL | MIL +100 | 54.0% | 6 | LOSS |
TOR@MIA | MIA +1.5 | 62.0% | 6 | WIN |
CHC@LAA | OVER 9.5 | 54.9% | 4 | LOSS |
BOS@NYY | CARLOS RODON UNDER 4.5 HITS ALLOWED | 54.2% | 4 | WIN |
KC@DET | DET -115 | 56.1% | 5 | WIN |
CHC@LAA | LAA +1.5 | 57.6% | 5 | LOSS |