Yankees vs. Cardinals
Prediction, Odds & Props
Aug 17 | MLB AI Picks

Updated: 2025-08-15T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The New York Yankees (around 64–57) travel to St. Louis to take on the Cardinals (around 61–61) in a late-summer duel that could swing the balance in both teams’ playoff hopes. The Yankees enter with superior firepower and run differential, while the Cardinals rely on home pitching, elite defense, and opportunistic situational hitting.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Aug 17, 2025

Start Time: 2:15 PM EST​

Venue: Busch Stadium​

Cardinals Record: (61-63)

Yankees Record: (66-57)

OPENING ODDS

NYY Moneyline: -149

STL Moneyline: +124

NYY Spread: -1.5

STL Spread: +1.5

Over/Under: 9

NYY
Betting Trends

  • New York has struggled against the spread recently, going just 3–7 in their last 10 games.

STL
Betting Trends

  • St. Louis has been strong defensively and at home, posting a 15–6 record in their last 30 games at Busch Stadium and showing resilience against tough opponents.

MATCHUP TRENDS

  • Despite the Yankees’ offensive edge, the Cardinals’ home authority and recent ATS success at Busch Stadium make Cardinals ML or Cardinals +1.5 on the run line attractive options given New York’s recent struggles to cover.

NYY vs. STL
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: N. Gorman over 0.5 Hits+Runs+RBI.

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New York vs St. Louis Prediction & Odds:
Free MLB Betting Insights for 8/17/25

The August 17 matchup between the New York Yankees and the St. Louis Cardinals at Busch Stadium features two clubs on the brink of very different late-season identities, as the Yankees aim to solidify their grip on a Wild Card berth in the American League while the Cardinals look to claw their way into the NL postseason picture behind home-field strength and pitching stability. Entering play at approximately 64–57, the Yankees continue to be powered by a lineup that blends elite slugging with recent reinforcements like Trent Grisham and Ben Rice, whose emergence has helped offset inconsistencies from once-core pieces like Gleyber Torres and Anthony Rizzo. At their best, New York can overwhelm any rotation with their power output, ranking top five in home runs and isolated power, particularly when Aaron Judge is locked in and Cody Bellinger is producing gap-to-gap. However, their issues lie in bullpen inconsistency and defensive lapses, areas that have cost them in late-game situations and contributed to a recent slide against the spread. The Cardinals, sitting close to 61–61, are still hanging around the postseason race despite lacking the offensive explosiveness of their AL counterparts. What they lack in firepower, they compensate for with elite defense—ranking first in MLB in Outs Above Average—and the ability to execute clean baseball late in games thanks to a reliable bullpen led by Ryan Helsley and JoJo Romero. On offense, the Cardinals rely on situational hitting from veterans like Nolan Arenado and Lars Nootbaar, as well as clutch contributions from Masyn Winn and Alec Burleson, who have emerged as productive bats during the second half.

The expected pitching matchup, with Jack Flaherty or Miles Mikolas toeing the rubber for St. Louis against a potentially younger Yankees arm such as Luis Gil or Clarke Schmidt, could tip in favor of the Cardinals, particularly if New York’s starter is still working back from injury or lacking rhythm. Busch Stadium has been a fortress for the Cardinals this summer, where they’ve gone 15–6 over their last 30 games and covered the run line at a profitable rate. Conversely, the Yankees have not traveled well in recent weeks, failing to cover in seven of their last 10 and showing vulnerabilities against contact-heavy teams that avoid strikeouts. This game profiles as a classic contrast in styles—New York’s big bats and boom-or-bust offense versus St. Louis’s finesse, defense-first approach and clutch bullpen arms. The outcome could hinge on whether the Yankees can capitalize early or if the Cardinals can keep the game close into the later innings, where their bullpen can shorten the game and their defensive sharpness can exploit any Yankee miscues. For bettors, this is a matchup where trends favor the home team’s consistency and tactical execution, especially given the Yankees’ struggles with spread coverage and bullpen leaks. With playoff implications hanging in the balance, this Sunday clash sets the stage for a pivotal test of each team’s identity—whether New York’s firepower can carry them through hostile territory, or if St. Louis’s calculated, contact-based baseball prevails in a must-have home game.

New York Yankees MLB Preview

The New York Yankees arrive in St. Louis for their August 17 matchup looking to build momentum in the crowded AL playoff race and shake off the inconsistencies that have plagued their midseason form. With a record hovering around 64–57, the Yankees remain in Wild Card contention, but their hold on a postseason spot has felt tenuous at times due to erratic pitching and an offense that can alternate between explosive and ice-cold. The return of Aaron Judge to full health has reignited their power stroke, as he continues to rank among the league leaders in home runs and slugging percentage, offering the kind of game-changing at-bats that opposing pitchers dread. Alongside Judge, the recent hot streak of Cody Bellinger has added another layer of threat to a Yankees lineup that can go deep at any time but has also struggled with strikeouts and hitting with runners in scoring position. Young contributors like Ben Rice and Oswald Peraza have given the offense sparks of energy, while DJ LeMahieu’s ability to grind out quality at-bats remains invaluable in the two-hole. However, injuries and inconsistency have thinned the Yankees’ starting rotation, with Gerrit Cole still ramping up and others like Nestor Cortes and Carlos Rodón facing mixed results. Luis Gil, Clarke Schmidt, or even a spot starter could be tasked with facing the Cardinals, which introduces an element of volatility that has cost New York games this season.

The bullpen, once a strength, has also been hit-or-miss—Clay Holmes has been serviceable in the closer role, but the middle innings have been vulnerable, especially when setup options like Ian Hamilton or Tommy Kahnle are off their game. Defensively, the Yankees rank in the middle of the pack in most advanced metrics, and while they have reduced their error totals compared to early in the season, lapses in outfield communication and infield execution have still led to costly runs in close games. On the road, New York has struggled to maintain consistency, especially when traveling to National League parks where they lose the DH and have to make tough lineup decisions. From an ATS perspective, the Yankees have failed to cover in seven of their last ten road games, an alarming trend that speaks to their up-and-down performance and tendency to underachieve when not playing in Yankee Stadium. The key to their success in this game will lie in their ability to jump out early, forcing St. Louis into higher-leverage bullpen usage, and avoiding the defensive miscues and bullpen collapses that have cost them in late innings. If Judge and Bellinger can deliver in key spots and the starter can give five competitive innings, the Yankees have enough firepower to steal a win on the road. However, if the bats go cold or the defense falters, they’ll be at risk of dropping another game to a Cardinals team that thrives on fundamentals and execution, especially at home.

The New York Yankees (around 64–57) travel to St. Louis to take on the Cardinals (around 61–61) in a late-summer duel that could swing the balance in both teams’ playoff hopes. The Yankees enter with superior firepower and run differential, while the Cardinals rely on home pitching, elite defense, and opportunistic situational hitting. New York vs St. Louis AI Prediction: Free MLB Betting Insights for Aug 17. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

St. Louis Cardinals MLB Preview

The St. Louis Cardinals enter their August 17 home matchup against the New York Yankees with a growing sense of urgency as they attempt to stay relevant in the National League Wild Card race. With a record hovering around 61–60, the Cardinals are very much alive in the postseason conversation, but they’ve struggled to maintain consistency, especially against American League opponents. Their offense, once the hallmark of the franchise, has shown signs of resurgence lately, with cornerstone veterans like Paul Goldschmidt and Nolan Arenado heating up after extended slumps earlier in the season. Goldschmidt’s ability to work counts and drive the ball to all fields remains a key to the offense, while Arenado’s improved glove work and timely extra-base hits have injected life into a lineup that at times felt stagnant in the first half. The breakout campaign from Masyn Winn has added a much-needed youthful spark, giving St. Louis a high-contact bat at the top of the order and dynamic range at shortstop. Behind the plate, Ivan Herrera continues to solidify his presence as the catcher of the future, combining defensive polish with surprising pop at the plate. On the mound, the Cardinals are expected to give the ball to Miles Mikolas, a veteran right-hander who has provided stability despite lacking overpowering stuff, relying on location, pitch sequencing, and ground-ball contact to get through lineups. While Mikolas won’t wow with strikeouts, he generally keeps the game within reach and allows his defense to work behind him, which is crucial against a Yankees lineup with game-breaking power.

The bullpen, headlined by closer Ryan Helsley and supported by JoJo Romero and Andrew Kittredge, has been one of the more reliable units in the NL, though it’s occasionally been overworked due to short outings by the rotation. One of the Cardinals’ key strengths remains their home-field execution—despite being just above .500 at Busch Stadium, they’ve shown the ability to grind out close games in front of a loyal fanbase that continues to show up in large numbers. Defensively, the Cardinals are among the most fundamentally sound teams in baseball, consistently turning double plays and preventing extra bases with intelligent positioning and crisp execution. From a betting perspective, St. Louis has covered the run line in six of its last nine home games, particularly thriving when holding early leads. Against a Yankees team that has struggled on the road and shown vulnerability late in games, the Cardinals will look to capitalize on their defensive edge and deeper bullpen. To secure the win, they’ll need to execute their game plan of manufacturing runs, limiting walks, and playing clean baseball. If they can force New York into a battle of attrition and avoid giving up the long ball, they’re well-positioned to come out on top and continue climbing in the Wild Card standings. With their veterans stepping up and young talent making a difference, this is a critical test for a Cardinals squad that believes it still has enough to make a postseason push.

New York vs. St. Louis Prop Picks (AI)

Remi is pouring through tons of data on each team. In fact, anytime the Yankees and Cardinals play there’s always several intriguing angles to key in on. Not to mention games played at Busch Stadium in Aug rarely follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: N. Gorman over 0.5 Hits+Runs+RBI.

New York vs. St. Louis Prediction (AI)

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Remi, our AI sports algorithm, has been pouring over millions of data from every angle between the Yankees and Cardinals and using recursive machine learning and cutting-edge AI to analyze the data to a single cover probability.

Oddly enough, we’ve seen the AI has been most fixated on the trending weight human bettors regularly put on St. Louis’s strength factors between a Yankees team going up against a possibly tired Cardinals team. We’ve found the true game analytics appear to reflect a moderate lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI New York vs St. Louis picks, computer picks Yankees vs Cardinals, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

Yankees Betting Trends

New York has struggled against the spread recently, going just 3–7 in their last 10 games.

Cardinals Betting Trends

St. Louis has been strong defensively and at home, posting a 15–6 record in their last 30 games at Busch Stadium and showing resilience against tough opponents.

Yankees vs. Cardinals Matchup Trends

Despite the Yankees’ offensive edge, the Cardinals’ home authority and recent ATS success at Busch Stadium make Cardinals ML or Cardinals +1.5 on the run line attractive options given New York’s recent struggles to cover.

New York vs. St. Louis Game Info

New York vs St. Louis starts on August 17, 2025 at 2:15 PM EST.

Spread: St. Louis +1.5
Moneyline: New York -149, St. Louis +124
Over/Under: 9

New York: (66-57)  |  St. Louis: (61-63)

Remi's searched hard and found the best prop for this matchup: N. Gorman over 0.5 Hits+Runs+RBI.. Prices move—always shop for the best number.

Despite the Yankees’ offensive edge, the Cardinals’ home authority and recent ATS success at Busch Stadium make Cardinals ML or Cardinals +1.5 on the run line attractive options given New York’s recent struggles to cover.

NYY trend: New York has struggled against the spread recently, going just 3–7 in their last 10 games.

STL trend: St. Louis has been strong defensively and at home, posting a 15–6 record in their last 30 games at Busch Stadium and showing resilience against tough opponents.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

New York vs. St. Louis Odds

AI algorithm Remi is pouring through loads of data on each team. In fact, anytime the New York vs St. Louis trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme altitude almost always follow normal, predictable patterns.

New York vs St. Louis Opening Odds

NYY Moneyline: -149
STL Moneyline: +124
NYY Spread: -1.5
STL Spread: +1.5
Over/Under: 9

New York vs St. Louis Live Odds

Games PTS ML SPR O/U
Sep 28, 2025 3:05PM EDT
Kansas City Royals
Oakland Athletics
9/28/25 3:05PM
Royals
Athletics
-155
+125
-1.5 (+104)
+1.5 (-130)
O 9.5 (-106)
U 9.5 (-121)
Sep 28, 2025 3:06PM EDT
Baltimore Orioles
New York Yankees
9/28/25 3:06PM
Orioles
Yankees
+160
-190
+1.5 (-120)
-1.5 (+100)
O 9 (-105)
U 9 (-115)
Sep 28, 2025 3:06PM EDT
Colorado Rockies
San Francisco Giants
9/28/25 3:06PM
Rockies
Giants
+240
-295
+1.5 (+118)
-1.5 (-142)
O 7.5 (-112)
U 7.5 (-108)
Sep 28, 2025 3:06PM EDT
Minnesota Twins
Philadelphia Phillies
9/28/25 3:06PM
Twins
Phillies
+168
-200
+1.5 (-122)
-1.5 (+102)
O 8 (-122)
U 8 (+100)
Sep 28, 2025 3:06PM EDT
Chicago White Sox
Washington Nationals
9/28/25 3:06PM
White Sox
Nationals
-104
-112
-1.5 (+158)
+1.5 (-192)
O 8.5 (-115)
U 8.5 (-105)
Sep 28, 2025 3:07PM EDT
Houston Astros
Los Angeles Angels
9/28/25 3:07PM
Astros
Angels
-134
+107
-1.5 (+118)
+1.5 (-152)
O 9.5 (-117)
U 9.5 (-109)
Sep 28, 2025 3:08PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/28/25 3:08PM
Rays
Blue Jays
+160
-190
+1.5 (-138)
-1.5 (+115)
O 7.5 (-115)
U 7.5 (-105)
Sep 28, 2025 3:10PM EDT
Los Angeles Dodgers
Seattle Mariners
9/28/25 3:10PM
Dodgers
Mariners
-102
-116
-1.5 (+160)
+1.5 (-194)
O 8 (-104)
U 8 (-118)
Sep 28, 2025 3:10PM EDT
Texas Rangers
Cleveland Guardians
9/28/25 3:10PM
Rangers
Guardians
+133
-167
+1.5 (-175)
-1.5 (+135)
O 8 (-114)
U 8 (-112)
Sep 28, 2025 3:10PM EDT
Arizona Diamondbacks
San Diego Padres
9/28/25 3:10PM
Diamondbacks
Padres
+108
-134
+1.5 (-230)
-1.5 (+170)
O 8 (-106)
U 8 (-121)
Sep 28, 2025 3:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/28/25 3:11PM
Reds
Brewers
+124
-146
+1.5 (-160)
-1.5 (+132)
O 7.5 (-115)
U 7.5 (-105)
Sep 28, 2025 3:11PM EDT
New York Mets
Miami Marlins
9/28/25 3:11PM
Mets
Marlins
-130
+110
-1.5 (+128)
+1.5 (-154)
O 8 (-122)
U 8 (+100)
Sep 28, 2025 3:16PM EDT
Pittsburgh Pirates
Atlanta Braves
9/28/25 3:16PM
Pirates
Braves
+176
-210
+1.5 (-122)
-1.5 (+102)
O 7.5 (-124)
U 7.5 (+102)
Sep 28, 2025 3:20PM EDT
St Louis Cardinals
Chicago Cubs
9/28/25 3:20PM
Cardinals
Cubs
 
-164
 
-1.5 (+132)
O 8.5 (+100)
U 8.5 (-122)
Sep 30, 2025 2:30PM EDT
San Diego Padres
Chicago Cubs
9/30/25 2:30PM
Padres
Cubs
+100
-120
pk
pk

MLB Past Picks

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We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers New York Yankees vs. St. Louis Cardinals on August 17, 2025 at Busch Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
ARI@SD SD -131 57.3% 4 WIN
DET@BOS BOS -115 56.4% 5 WIN
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS