Yankees vs Cardinals Prediction — AI Finds CAN'T MISS MLB Lines & Props (Aug 15)
Updated: 2025-08-13T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The New York Yankees, sitting around 64–57 and firmly in the AL East playoff hunt, take an interleague trip to face the 61–61 St. Louis Cardinals, who are holding their ground in a tightly packed NL Central playoff chase.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Aug 15, 2025
Start Time: 8:15 PM EST
Venue: Busch Stadium
Cardinals Record: (61-61)
Yankees Record: (64-57)
OPENING ODDS
NYY Moneyline: -134
STL Moneyline: +113
NYY Spread: -1.5
STL Spread: +1.5
Over/Under: 9
NYY
Betting Trends
- While a precise ATS record wasn’t easily accessible, teams in their position—above .500 with playoff aspirations—typically hold a solid performance against the spread, particularly on the road.
STL
Betting Trends
- St. Louis has shown decent value at home, especially in close games, as reflected in an approximate 35–27 home record, suggesting relative strength in late-game execution.
MATCHUP TRENDS
- New York enters as the projected favorite, relying on depth, pitching, and offensive firepower. The Cardinals, however, perform best when the game remains tight—making the run-line angle (e.g., Cardinals +1.5) or the under total particularly worth a look, especially if both pitching matchups suppress offense.
NYY vs. STL
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: A. Volpe over 4.5 Fantasy Score.
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New York vs St. Louis Prediction & Odds:
Free MLB Betting Insights for 8/15/25
Offensively, the Yankees hold a clear edge in firepower, but the Cardinals are capable of exploiting pitchers with small-ball tactics and excellent situational hitting. Busch Stadium’s pitcher-friendly dimensions could play a role in neutralizing some of New York’s home run threat, which puts added emphasis on the Yankees’ ability to drive runners in with timely base hits. On defense, both clubs have been steady, with St. Louis showcasing one of the league’s more efficient infields, while New York’s outfield range and athleticism help compensate for average infield play. The Cardinals will aim to keep the game close into the later innings, where they can turn it over to Ryan Helsley and a bullpen that has been sharp at home. The Yankees, by contrast, will try to jump on St. Louis pitching early and avoid a close game that could turn into a battle of bullpens. From a betting and analytical standpoint, this game presents intriguing angles. The Yankees are likely slight road favorites, but the Cardinals have performed admirably in tight games at home and could offer value on the run line or moneyline if the starting pitching matchup favors them. Bettors may also look at the under, particularly if both bullpens are in good shape, given Busch Stadium’s tendency to keep scoring in check. The Yankees will enter with more pressure to win, while the Cardinals will look to take advantage of the home crowd and grind out another key win in their pursuit of postseason baseball. With both clubs desperate to gain ground in their respective divisions, this interleague contest should be competitive, strategic, and full of playoff-caliber intensity.
Belli Ballin' 💥 pic.twitter.com/79DNvHin8Z
— New York Yankees (@Yankees) August 14, 2025
New York Yankees MLB Preview
The New York Yankees enter their August 15, 2025 road matchup against the St. Louis Cardinals with a 64–57 record and a clear sense of urgency as the postseason race heats up. With the AL East continuing to be one of the most competitive divisions in baseball, the Yankees are in a dogfight for a Wild Card spot and cannot afford to drop winnable games, especially against non-divisional opponents. The loss of ace Gerrit Cole for the season due to Tommy John surgery could have been a season-defining blow, but the team has managed to stay afloat behind contributions from younger arms like Luis Gil and steady performances from Nestor Cortes. Offensively, the Yankees remain one of the most dangerous lineups in the league, built around the elite combination of Juan Soto and Aaron Judge. Soto’s ability to get on base and hit for power, paired with Judge’s home run production and plate presence, forms a potent one-two punch that few opposing staffs have been able to contain. They’re supported by a cast that includes Gleyber Torres, Anthony Volpe, and DJ LeMahieu, all of whom have had stretches of impact throughout the season. This lineup can change the game with one swing, making them a constant threat no matter the score or inning. On the mound, while the Yankees no longer boast the overpowering rotation depth they had at the start of the year, they’ve adapted by leaning on bullpen matchups and aggressive pitch sequencing. Their relief corps, anchored by Clay Holmes and setup arms like Wandy Peralta and Scott Effross, has kept them competitive in late-game situations.
Holmes in particular has been excellent in closing tight games, converting high-leverage saves and limiting hard contact. Defense has also been a plus for New York in 2025, especially in the outfield, where Judge, Soto, and Alex Verdugo have combined for solid range and arm strength. Their infield, led by the defensive strides of Volpe and the versatility of LeMahieu, has limited errors and helped minimize extra opportunities for opponents. The Yankees have also improved their base running and situational execution, two areas that were lacking in prior seasons but have seen noticeable gains under manager Aaron Boone’s staff this year. Strategically, New York will enter this interleague series with a focus on setting the tone early. They thrive when playing with a lead and will look to jump on St. Louis starters quickly to avoid letting the game become a late-inning toss-up. Against a Cardinals team that plays well at home and has a strong late bullpen, the Yankees will need to build an early cushion and keep the pressure on. They’ve shown the ability to win both shootouts and low-scoring duels, giving them flexibility in how they approach different game scenarios. From a betting perspective, the Yankees are typically strong favorites in matchups like these, though recent ATS trends suggest they can occasionally fail to cover against teams with gritty pitching and solid home records like the Cardinals. Still, with more star power, a sense of urgency, and the better overall roster, New York enters this game expecting to win and stay alive in the AL playoff chase.

Credit: USA TODAY/IMAGN
St. Louis Cardinals MLB Preview
The St. Louis Cardinals head into their August 15, 2025 matchup against the visiting New York Yankees with a 61–61 record and a season that has hovered on the edge of relevance thanks to a mix of veteran leadership, emerging young talent, and gritty late-game execution. While they remain fourth in the National League Central, their position within a relatively weak division and the expanded Wild Card format has kept them squarely in the postseason conversation. St. Louis has found a way to keep games close and competitive at Busch Stadium, where they’ve posted a solid 35–27 home record and thrived in games decided by two runs or fewer. Offensively, the Cardinals are not a powerhouse by modern standards, but their contact-based approach, patient at-bats, and willingness to play small ball have helped them manufacture runs against more talented lineups. The veteran duo of Nolan Arenado and Paul Goldschmidt continues to serve as the backbone of the lineup, with Arenado leading the team in RBIs and setting the tone defensively at third base. Goldschmidt, while not matching his MVP-caliber numbers from recent seasons, remains a dangerous bat and steady presence in the clubhouse. Around them, the Cardinals have begun incorporating more youth into the starting lineup, with players like Brendan Donovan and Masyn Winn adding speed, defensive range, and energy to the everyday roster. The Cardinals’ pitching has been inconsistent, but at home they’ve managed to maximize the strengths of their staff by taking advantage of Busch Stadium’s pitcher-friendly dimensions and relying on a bullpen that has been quietly effective.
While their rotation lacks an ace, veterans like Miles Mikolas and Steven Matz have delivered valuable innings, keeping St. Louis in games long enough for the bullpen to take over. Ryan Helsley has reemerged as one of the more dominant closers in the National League, regularly shutting the door in the ninth and giving the team confidence in one-run contests. Helsley’s fastball-slider combination has made him nearly unhittable when ahead in the count, and his presence has turned many tight home games into wins for the Cardinals. Defensively, St. Louis has remained one of the most disciplined teams in the majors, with Arenado and Tommy Edman forming one of the sharpest left-side infield tandems in baseball. Their ability to convert ground balls into outs and avoid costly mistakes has been crucial in offsetting some of the rotation’s limitations and keeping opponents from capitalizing on big innings. Against the Yankees, the Cardinals will need to control the tempo early, avoid falling behind to their power-packed lineup, and execute their contact-and-run strategy with precision. The key will be preventing New York’s top bats from dictating the pace and turning the game into a slugfest. If St. Louis can keep the game within reach and avoid defensive lapses, they have the tools and home-field poise to grind out another tight win. From a betting perspective, the Cardinals have been strong on the run line in games at Busch Stadium where they are slight underdogs, and their ability to keep games close with sharp bullpen usage and defensive execution gives them value even when facing superior lineups like the Yankees. This game is an opportunity for St. Louis to prove they belong in the playoff picture and to keep their momentum alive heading into the final stretch of the season.
NOOOOOOOT goes deep into the bullpen! 💣 pic.twitter.com/x7f0qRW34e
— St. Louis Cardinals (@Cardinals) August 13, 2025
New York vs. St. Louis Prop Picks (AI)
New York vs. St. Louis Prediction (AI)

Remi, our AI sports wizard, has been pouring over exorbitant amounts of data from every simulation between the Yankees and Cardinals and using recursive machine learning and industry leading AI to crunch the data to a single cover probability.
Oddly enough, we’ve seen the AI has been most keyed in on the growing weight human bettors often put on coaching factors between a Yankees team going up against a possibly improved Cardinals team. In reality, the true game analytics appear to reflect a strong lean against one Vegas line specifically.
Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.
Below is our current AI New York vs St. Louis picks, computer picks Yankees vs Cardinals, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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MLB | 10/20 | SEA@TOR | UNLOCK THIS PICK | 2 |
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MLB | 10/20 | SEA@TOR | UNLOCK THIS PICK | 0 |
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.
Yankees Betting Trends
While a precise ATS record wasn’t easily accessible, teams in their position—above .500 with playoff aspirations—typically hold a solid performance against the spread, particularly on the road.
Cardinals Betting Trends
St. Louis has shown decent value at home, especially in close games, as reflected in an approximate 35–27 home record, suggesting relative strength in late-game execution.
Yankees vs. Cardinals Matchup Trends
New York enters as the projected favorite, relying on depth, pitching, and offensive firepower. The Cardinals, however, perform best when the game remains tight—making the run-line angle (e.g., Cardinals +1.5) or the under total particularly worth a look, especially if both pitching matchups suppress offense.
New York vs. St. Louis Game Info
What time does New York vs St. Louis start on August 15, 2025?
New York vs St. Louis starts on August 15, 2025 at 8:15 PM EST.
Where is New York vs St. Louis being played?
Venue: Busch Stadium.
What are the opening odds for New York vs St. Louis?
Spread: St. Louis +1.5
Moneyline: New York -134, St. Louis +113
Over/Under: 9
What are the records for New York vs St. Louis?
New York: (64-57) | St. Louis: (61-61)
What is the AI best bet for New York vs St. Louis?
Remi's searched hard and found the best prop for this matchup: A. Volpe over 4.5 Fantasy Score.. Prices move—always shop for the best number.
What are New York vs St. Louis trending bets?
New York enters as the projected favorite, relying on depth, pitching, and offensive firepower. The Cardinals, however, perform best when the game remains tight—making the run-line angle (e.g., Cardinals +1.5) or the under total particularly worth a look, especially if both pitching matchups suppress offense.
What are New York trending bets?
NYY trend: While a precise ATS record wasn’t easily accessible, teams in their position—above .500 with playoff aspirations—typically hold a solid performance against the spread, particularly on the road.
What are St. Louis trending bets?
STL trend: St. Louis has shown decent value at home, especially in close games, as reflected in an approximate 35–27 home record, suggesting relative strength in late-game execution.
Where can I find AI Picks for New York vs St. Louis?
See our latest MLB picks and odds pages for 2025 to compare prices before you bet.
New York vs. St. Louis Odds
AI algorithm Remi is pouring through tons of stats on each line. In fact, anytime the New York vs St. Louis trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme hostile environments almost always follow normal, predictable betting trends.
New York vs St. Louis Opening Odds
NYY Moneyline:
-134 STL Moneyline: +113
NYY Spread: -1.5
STL Spread: +1.5
Over/Under: 9
New York vs St. Louis Live Odds
Games | PTS | ML | SPR | O/U | |
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Oct 24, 2025 9:08PM EDT
Los Angeles Dodgers
Toronto Blue Jays
10/24/25 9:08PM
Dodgers
Blue Jays
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–
–
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-140
+127
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-1.5 (+124)
+1.5 (-140)
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O 7.5 (+107)
U 7.5 (-123)
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MLB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers New York Yankees vs. St. Louis Cardinals on August 15, 2025 at Busch Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
TOR@SEA | OVER 7 | 54.9% | 3 | WIN |
LAD@MIL | UNDER 7.5 | 56.6% | 6 | WIN |
TOR@NYY | OVER 8 | 54.9% | 4 | WIN |
TOR@NYY | CARLOS RODON OVER 1.5 TOTAL WALKS ALLOWED | 53.3% | 3 | WIN |
NYY@TOR | OVER 7.5 | 54.8% | 2 | WIN |
LAD@PHI | OVER 7 | 53.8% | 3 | WIN |
SD@CHC | CHC -109 | 53.8% | 3 | WIN |
SD@CHC | OVER 7.5 | 54.5% | 4 | LOSS |
SD@CHC | CHC -111 | 54.8% | 4 | LOSS |
CIN@LAD | SHOHEI OHTANI OVER 1.5 BASES | 53.5% | 3 | WIN |
BOS@NYY | OVER 7 | 53.8% | 3 | LOSS |
CIN@LAD | ELLY DE LA CRUZ OVER 0.5 BASES | 54.4% | 4 | LOSS |
ARI@SD | SD -131 | 57.3% | 4 | WIN |
DET@BOS | BOS -115 | 56.4% | 5 | WIN |
NYM@CHC | NYM -110 | 54.1% | 3 | WIN |
HOU@ATH | ATH +118 | 50.8% | 4 | WIN |
NYM@CHC | OVER 7 | 54.5% | 3 | WIN |
STL@SF | OVER 7.5 | 55.9% | 5 | LOSS |
KC@LAA | TYLER TOLBERT UNDER 1.5 BASES | 54.4% | 4 | WIN |
MIL@SD | UNDER 9 | 54.7% | 4 | WIN |
MIA@PHI | KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS | 53.3% | 3 | WIN |
WAS@NYM | OVER 8.5 | 56.1% | 6 | LOSS |
LAA@COL | COL +108 | 50.5% | 3 | WIN |
TOR@KC | UNDER 9 | 54.7% | 4 | LOSS |
SEA@KC | KC +1.5 | 62.3% | 5 | LOSS |
NYY@MIN | OVER 9 | 55.1% | 4 | WIN |
MIA@COL | OVER 10.5 | 55.0% | 4 | WIN |
MIA@COL | AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS | 54.3% | 4 | WIN |
SEA@KC | BOBBY WITT UNDER 0.5 SINGLES | 54.4% | 4 | LOSS |
PHI@LAD | LAD -113 | 54.7% | 4 | LOSS |
NYY@BOS | OVER 7.5 | 54.3% | 3 | WIN |
KC@PHI | PHI -130 | 58.3% | 4 | WIN |
LAD@SF | OVER 7.5 | 54.7% | 4 | LOSS |
NYM@PHI | PHI -122 | 55.6% | 4 | WIN |
KC@CLE | KC -104 | 52.0% | 3 | WIN |
CIN@SD | JAKE CRONEWORTH OVER 0.5 HITS | 53.1% | 3 | WIN |
WAS@MIA | MIA -123 | 55.2% | 4 | LOSS |
LAA@KC | UNDER 9.5 | 54.9% | 3 | WIN |
TEX@ARI | UNDER 9 | 54.2% | 4 | WIN |
SF@COL | UNDER 11.5 | 56.4% | 6 | LOSS |
SF@COL | RAFAEL DEVERS OVER 1.5 BASES | 56.1% | 6 | WIN |
MIA@WAS | WAS -110 | 54.4% | 4 | WIN |
NYM@DET | OVER 8.5 | 54.5% | 4 | WIN |
TEX@ARI | UNDER 9.5 | 56.4% | 6 | WIN |
TEX@ARI | ALEJANDRO OSUNA UNDER 1.5 BASES | 54.1% | 4 | LOSS |
ATL@CHC | CHC -116 | 55.1% | 3 | WIN |
PHI@MIL | OVER 8.5 | 55.0% | 3 | WIN |
ARI@LAD | SHOHEI OHTANI OVER 2.5 BASES | 54.2% | 4 | WIN |
SEA@CLE | CLE +1.5 | 57.2% | 3 | WIN |
CHC@SF | CHC -105 | 54.1% | 4 | LOSS |
NYY@CHW | RYAN MCMAHON OVER 0.5 BASES | 54.1% | 4 | WIN |