Guardians vs White Sox Prediction — AI Finds CAN'T MISS MLB Lines & Props (Aug 10)
Updated: 2025-08-08T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
Sunday, August 10, 2025, sees the Cleveland Guardians visiting the Chicago White Sox at Rate Field for a divisional showdown, with first pitch scheduled for 2:10 p.m. ET. The Guardians enter as moderate favorites, and the projected totals suggest a competitive, mid-range scoring affair.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Aug 10, 2025
Start Time: 2:10 PM EST
Venue: Rate Field
White Sox Record: (42-75)
Guardians Record: (61-55)
OPENING ODDS
CLE Moneyline: -141
CHW Moneyline: +118
CLE Spread: -1.5
CHW Spread: +1.5
Over/Under: 8.5
CLE
Betting Trends
- Cleveland has covered the run line in about 51.8% of their games this season.
CHW
Betting Trends
- Chicago has been stronger ATS, covering the run line in approximately 58.0% of their games in 2025.
MATCHUP TRENDS
- With the Guardians’ just-above-even ATS record on the road and the White Sox performing better than .500 ATS at home, this matchup appears primed for a tight, one-run decision — a true divisional coin flip.
CLE vs. CHW
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: K. Manzardo over 0.5 Total Bases.
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Cleveland vs Chicago White Sox Prediction & Odds:
Free MLB Betting Insights for 8/10/25
This group’s willingness to run—whether through steals, aggressive first-to-third advances, or hit-and-run plays—has made them a constant problem for teams like Chicago that rank near the bottom of the league in defensive runs saved. The Guardians will likely seek to exploit the White Sox’s outfield positioning and infield range to turn routine hits into extra-base opportunities. Chicago’s offense, while inconsistent over the full season, has been more productive in the past month. Veterans like Adam Benintendi bring quality plate appearances, and younger contributors such as Lenyn Sosa, Colson Montgomery, and Curtis Mead have delivered timely contact. Their best path to scoring against Cecconi will be to jump on early-count fastballs before he can get to his secondary pitches, as well as to find ways to force Cleveland’s defenders into hurried plays, since the Guardians’ defensive strength is built more on positioning and anticipation than raw range. In the late innings, Cleveland holds a bullpen advantage with one of the league’s better FIPs and a deep stable of matchup-ready arms that can shorten games to six or seven innings if Cecconi gives them a lead. Chicago’s relief corps, though improved in spots, still faces questions about holding slim advantages against high-contact lineups. This means Martin’s ability to pitch into the sixth or seventh could be critical to keeping the White Sox in control of their matchups. Ultimately, this game projects as a fundamentals-driven contest where small details—accurate relays, execution of double plays, discipline in two-strike counts, and avoiding walks that precede extra-base hits—will determine the winner. With Cleveland’s road success in divisional games and Chicago’s better-than-.500 ATS mark at home, the likeliest script is a one-run margin decided by whether the Guardians can maintain their recent form and bullpen dominance or the White Sox can seize the moment with a timely rally and flawless late-game execution in front of their home crowd.
Going for back-to-back sweeps tomorrow!#GuardsBall | #GuardiWWWWWins pic.twitter.com/jzmLwXCTpt
— Cleveland Guardians (@CleGuardians) August 10, 2025
Cleveland Guardians MLB Preview
The Cleveland Guardians enter Sunday’s finale at Guaranteed Rate Field riding the momentum of a four-game winning streak and a growing sense of confidence that their balanced roster can navigate both the demands of the playoff chase and the challenges of divisional road games, where they have been particularly strong in 2025 with a notable ATS record that reflects their ability to win close contests away from home. They hand the ball to right-hander Slade Cecconi, whose 3.72 ERA underscores his efficiency, strike-throwing ability, and knack for inducing weak contact, making him a reliable option to set the tone and protect the bullpen’s depth for the late innings. His success in this game will hinge on working ahead in counts to neutralize a White Sox lineup that has shown flashes of improved production over the past month but still struggles with consistency when forced into defensive at-bats. Cleveland’s offense is built on a disciplined, contact-oriented approach spearheaded by José Ramírez’s mix of power and precision, Steven Kwan’s elite on-base skills, and the gap-hitting presence of Kyle Manzardo and Daniel Schneemann, who can extend innings and punish mistakes by driving balls into the alleys.
This group’s aggressive yet calculated baserunning adds an extra layer of pressure for Chicago’s defense, which has ranked near the bottom in runs saved and will be tested on relays, cutoffs, and infield range. The Guardians will likely emphasize long plate appearances early to elevate Davis Martin’s pitch count, with the goal of getting into a White Sox bullpen that has been less consistent in protecting slim leads. Once the late innings arrive, Cleveland’s relief corps—one of the most effective in the league by FIP—can leverage favorable matchups to shut the door. Defensively, the Guardians’ strength lies in positioning and execution, which should help counteract Chicago’s recent offensive uptick, and in a park like Guaranteed Rate Field, where well-struck balls can carry, their ability to track down drives in the gaps and make quick, accurate throws will be essential to controlling the extra base. Tactically, manager Stephen Vogt is likely to greenlight stolen base attempts in the right situations and use situational hitting, such as hit-and-run plays or sacrifice opportunities, to manufacture runs if the game stays low scoring. If Cecconi can deliver six efficient innings, the lineup continues to grind out quality at-bats, and the bullpen remains sharp, Cleveland will be in strong position to close the series with a road win that not only keeps them climbing in the standings but also reinforces their reputation as a team that excels in executing the finer points of the game when it matters most.

Credit: USA TODAY/IMAGN
Chicago White Sox White Sox MLB Preview
The Chicago White Sox approach Sunday’s finale at Guaranteed Rate Field with the opportunity to punctuate a challenging season by taking a game from a playoff-contending Cleveland Guardians club, and they will lean on a recent stretch of improved offense and solid home ATS results to give themselves a fighting chance in front of their own crowd. Starting pitcher Davis Martin, who enters with a 4.11 ERA, will need to be precise from the outset, using his fastball command to get ahead in counts and mixing his off-speed pitches to keep Cleveland’s disciplined hitters from sitting on one offering. Falling behind will open the door for long at-bats that wear him down and increase the odds of baserunners through walks or singles. The White Sox’s offensive blueprint will be to capitalize on the momentum they have shown in the past month, with veterans like Adam Benintendi delivering consistent contact and younger contributors such as Lenyn Sosa, Colson Montgomery, and Curtis Mead providing flashes of timely hitting. Their best chance of scoring against Slade Cecconi will come from jumping on early-count fastballs before he can settle into a rhythm with his command and sequencing.
Defensively, Chicago must play a clean game to counter Cleveland’s aggressive baserunning and gap-hitting tendencies, which means crisp relay throws from the outfield, sure-handed infield work to convert potential double plays, and avoiding miscues that give away free 90 feet. The bullpen, while serviceable at times, has been inconsistent, so manager Will Venable will have to be proactive with matchups, possibly using his best arms earlier in high-leverage moments rather than saving them strictly for the ninth, especially against the heart of Cleveland’s order. Strategically, the Sox can benefit from small-ball tactics, such as perfectly executed bunts, hit-and-run plays, and stolen base attempts, to generate runs without relying solely on extra-base hits, which could be harder to come by against a Guardians pitching staff that has excelled at limiting slugging. If Martin can pitch into the sixth or seventh inning with the game still close, the offense finds a way to cash in on its run-scoring opportunities, and the defense avoids the types of errors that have cost them in past tight contests, Chicago can put itself in position to grind out a one-run victory, send the fans home with a feel-good win, and build on the incremental progress they have made over the second half of the season.
Burke on the bump! pic.twitter.com/1GHeEctmN2
— Chicago White Sox (@whitesox) August 9, 2025
Cleveland vs. Chicago White Sox Prop Picks (AI)
Cleveland vs. Chicago White Sox Prediction (AI)

Remi, our AI sports wizard, has been pouring over millions of data from every facet between the Guardians and White Sox and using recursive machine learning and impressive AI to crunch the data to a single cover probability.
Interestingly enough, the data has been most keyed in on the unproportionally assigned emphasis knucklehead sportsbettors often put on player performance factors between a Guardians team going up against a possibly healthy White Sox team. Trends look to say the true game analytics might reflect a moderate lean against one Vegas line in particular.
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Below is our current AI Cleveland vs Chicago White Sox picks, computer picks Guardians vs White Sox, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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MLB | 10/20 | SEA@TOR | UNLOCK THIS PICK | 2 |
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MLB | 10/20 | SEA@TOR | UNLOCK THIS PICK | 0 |
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.
Guardians Betting Trends
Cleveland has covered the run line in about 51.8% of their games this season.
White Sox Betting Trends
Chicago has been stronger ATS, covering the run line in approximately 58.0% of their games in 2025.
Guardians vs. White Sox Matchup Trends
With the Guardians’ just-above-even ATS record on the road and the White Sox performing better than .500 ATS at home, this matchup appears primed for a tight, one-run decision — a true divisional coin flip.
Cleveland vs. Chicago White Sox Game Info
What time does Cleveland vs Chicago White Sox start on August 10, 2025?
Cleveland vs Chicago White Sox starts on August 10, 2025 at 2:10 PM EST.
Where is Cleveland vs Chicago White Sox being played?
Venue: Rate Field.
What are the opening odds for Cleveland vs Chicago White Sox?
Spread: Chicago White Sox +1.5
Moneyline: Cleveland -141, Chicago White Sox +118
Over/Under: 8.5
What are the records for Cleveland vs Chicago White Sox?
Cleveland: (61-55) | Chicago White Sox: (42-75)
What is the AI best bet for Cleveland vs Chicago White Sox?
Remi's searched hard and found the best prop for this matchup: K. Manzardo over 0.5 Total Bases.. Prices move—always shop for the best number.
What are Cleveland vs Chicago White Sox trending bets?
With the Guardians’ just-above-even ATS record on the road and the White Sox performing better than .500 ATS at home, this matchup appears primed for a tight, one-run decision — a true divisional coin flip.
What are Cleveland trending bets?
CLE trend: Cleveland has covered the run line in about 51.8% of their games this season.
What are Chicago White Sox trending bets?
CHW trend: Chicago has been stronger ATS, covering the run line in approximately 58.0% of their games in 2025.
Where can I find AI Picks for Cleveland vs Chicago White Sox?
See our latest MLB picks and odds pages for 2025 to compare prices before you bet.
Cleveland vs. Chicago White Sox Odds
Remi is pouring through mountains of stats on each team. In fact, anytime the Cleveland vs Chicago White Sox trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme temps can often follow normal, predictable patterns.
Cleveland vs Chicago White Sox Opening Odds
CLE Moneyline:
-141 CHW Moneyline: +118
CLE Spread: -1.5
CHW Spread: +1.5
Over/Under: 8.5
Cleveland vs Chicago White Sox Live Odds
Games | PTS | ML | SPR | O/U | |
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Oct 24, 2025 8:00PM EDT
Los Angeles Dodgers
Toronto Blue Jays
10/24/25 8PM
Dodgers
Blue Jays
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–
–
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-143
+130
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-1.5 (+120)
+1.5 (-140)
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O 7.5 (+105)
U 7.5 (-125)
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MLB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Cleveland Guardians vs. Chicago White Sox White Sox on August 10, 2025 at Rate Field.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
TOR@SEA | OVER 7 | 54.9% | 3 | WIN |
LAD@MIL | UNDER 7.5 | 56.6% | 6 | WIN |
TOR@NYY | OVER 8 | 54.9% | 4 | WIN |
TOR@NYY | CARLOS RODON OVER 1.5 TOTAL WALKS ALLOWED | 53.3% | 3 | WIN |
NYY@TOR | OVER 7.5 | 54.8% | 2 | WIN |
LAD@PHI | OVER 7 | 53.8% | 3 | WIN |
SD@CHC | CHC -109 | 53.8% | 3 | WIN |
SD@CHC | OVER 7.5 | 54.5% | 4 | LOSS |
SD@CHC | CHC -111 | 54.8% | 4 | LOSS |
CIN@LAD | SHOHEI OHTANI OVER 1.5 BASES | 53.5% | 3 | WIN |
BOS@NYY | OVER 7 | 53.8% | 3 | LOSS |
CIN@LAD | ELLY DE LA CRUZ OVER 0.5 BASES | 54.4% | 4 | LOSS |
ARI@SD | SD -131 | 57.3% | 4 | WIN |
DET@BOS | BOS -115 | 56.4% | 5 | WIN |
NYM@CHC | NYM -110 | 54.1% | 3 | WIN |
HOU@ATH | ATH +118 | 50.8% | 4 | WIN |
NYM@CHC | OVER 7 | 54.5% | 3 | WIN |
STL@SF | OVER 7.5 | 55.9% | 5 | LOSS |
KC@LAA | TYLER TOLBERT UNDER 1.5 BASES | 54.4% | 4 | WIN |
MIL@SD | UNDER 9 | 54.7% | 4 | WIN |
MIA@PHI | KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS | 53.3% | 3 | WIN |
WAS@NYM | OVER 8.5 | 56.1% | 6 | LOSS |
LAA@COL | COL +108 | 50.5% | 3 | WIN |
TOR@KC | UNDER 9 | 54.7% | 4 | LOSS |
SEA@KC | KC +1.5 | 62.3% | 5 | LOSS |
NYY@MIN | OVER 9 | 55.1% | 4 | WIN |
MIA@COL | OVER 10.5 | 55.0% | 4 | WIN |
MIA@COL | AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS | 54.3% | 4 | WIN |
SEA@KC | BOBBY WITT UNDER 0.5 SINGLES | 54.4% | 4 | LOSS |
PHI@LAD | LAD -113 | 54.7% | 4 | LOSS |
NYY@BOS | OVER 7.5 | 54.3% | 3 | WIN |
KC@PHI | PHI -130 | 58.3% | 4 | WIN |
LAD@SF | OVER 7.5 | 54.7% | 4 | LOSS |
NYM@PHI | PHI -122 | 55.6% | 4 | WIN |
KC@CLE | KC -104 | 52.0% | 3 | WIN |
CIN@SD | JAKE CRONEWORTH OVER 0.5 HITS | 53.1% | 3 | WIN |
WAS@MIA | MIA -123 | 55.2% | 4 | LOSS |
LAA@KC | UNDER 9.5 | 54.9% | 3 | WIN |
TEX@ARI | UNDER 9 | 54.2% | 4 | WIN |
SF@COL | UNDER 11.5 | 56.4% | 6 | LOSS |
SF@COL | RAFAEL DEVERS OVER 1.5 BASES | 56.1% | 6 | WIN |
MIA@WAS | WAS -110 | 54.4% | 4 | WIN |
NYM@DET | OVER 8.5 | 54.5% | 4 | WIN |
TEX@ARI | UNDER 9.5 | 56.4% | 6 | WIN |
TEX@ARI | ALEJANDRO OSUNA UNDER 1.5 BASES | 54.1% | 4 | LOSS |
ATL@CHC | CHC -116 | 55.1% | 3 | WIN |
PHI@MIL | OVER 8.5 | 55.0% | 3 | WIN |
ARI@LAD | SHOHEI OHTANI OVER 2.5 BASES | 54.2% | 4 | WIN |
SEA@CLE | CLE +1.5 | 57.2% | 3 | WIN |
CHC@SF | CHC -105 | 54.1% | 4 | LOSS |
NYY@CHW | RYAN MCMAHON OVER 0.5 BASES | 54.1% | 4 | WIN |