White Sox vs. Mariners
Prediction, Odds & Props
Aug 06 | MLB AI Picks

Updated: 2025-08-04T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Chicago White Sox visit T-Mobile Park to face the Seattle Mariners on August 6, 2025, with first pitch scheduled around 9:40 PM ET. Seattle enters as a clear favorite—about –1.5 on the run line and –130 on the moneyline—with total runs projected near 7.5 in what appears to be a spot favoring the hosts.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Aug 06, 2025

Start Time: 9:40 PM EST​

Venue: T-Mobile Park​

Mariners Record: (61-53)

White Sox Record: (42-71)

OPENING ODDS

CHW Moneyline: +213

SEA Moneyline: -264

CHW Spread: +1.5

SEA Spread: -1.5

Over/Under: 7.5

CHW
Betting Trends

  • Chicago is carrying a modest 20–17 overall record against the run line in 2025, but that splits into a 17–15 mark on the road, showing they’ve been slightly above .500 as visitors recently.

SEA
Betting Trends

  • Seattle has struggled in ATS markets this season with a 42 percent cover rate, making them one of MLB’s least reliable home favorites.

MATCHUP TRENDS

  • Despite their poor overall ATS numbers, Chicago has a 14–11 ATS record in their last 25 Wednesday games, indicating their ability to stay competitive mid‑week.

CHW vs. SEA
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: L. Robert over 5 Fantasy Score.

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Chicago White Sox vs Seattle Prediction & Odds:
Free MLB Betting Insights for 8/6/25

The Chicago White Sox travel to Seattle’s T-Mobile Park on August 6 to close out a three-game series against the Mariners, opening as underdogs with Seattle favored by about –1.5 on the run line and –258 on the moneyline, and a total set near 7.5 runs, reflecting clear expectations for a Mariners edge in a game where Seattle’s home pitching and offense overshadow Chicago’s underwhelming overall record; yet from a betting standpoint the matchup presents mixed signals—Seattle covers just about 42 percent of ATS games this season, while the Sox have held around 17–15 ATS on the road and a solid 14–11 ATS mark in Wednesday games, making Chicago a contrarian candidate when the line is sufficiently wide. Chicago hands the ball to Jonathan Cannon, who enters with a 4–8 record and a 4.77 ERA but provides reliable command, a low walk rate, and ability to limit hard contact; his advanced metrics show barrel rates under 10 percent and average exit velocity under 90 mph, making him capable of avoiding big innings despite not missing many bats. Opposing him is Seattle ace Bryan Woo, who boasts a 3.11 ERA, a 0.97 WHIP, and 127 strikeouts over 133 innings—ranked among the league’s top starters in efficiency metrics—bringing elite strikeout-to-walk ratios into his T-Mobile home zone where his fastball and sinker combination thrive. Offensively, the Mariners are powered by prolific sluggers Cal Raleigh with 42 home runs and Eugenio Suárez near the top of the RBI leaderboard; despite overall decline in batting average since the All-Star break, their middle of the order still represents a punch Boston struggles to suppress.

The White Sox counter with a post-break resurgence led by Colson Montgomery, who ranks among MLB leaders in RBIs since All-Star, along with contributions from Lenyn Sosa and Luis Robert Jr. in on-base and situational run creation, fueling Chicago’s surprising 10–5 second-half record and making them dangerous in tight matchups. Betting trends favor Seattle on the moneyline due to talent gap and home comfort, but Seattle’s poor ATS history means Chicago may carry legitimate value at +1.5, especially considering their Wednesday performance and Cannon’s ability to navigate contact. With totals around 7.5, this game projects as a low‑to‑moderate scoring contest where quality starts and bullpen reliability are the keys—Woo’s efficient style and Seattle’s home atmosphere give them the edge to control tempo, yet a disciplined, methodical Sox lineup and Cannon’s command could keep this within striking distance. Bullpen matchups may be decisive: Seattle’s relief corps is deeper, but Chicago’s bullpen has held up in recent road games and may keep the run differential small if Cannon pushes six innings. From a betting perspective, Seattle’s upside lies in closing strong and covering a modest spread, while Chicago’s upside lies in keeping it close and potentially winning outright if Woo falters early—positioning this as a tight contest where smart timing and pitching execution may override raw wins, and providing run-line value for those willing to back a scrappy road underdog with situational positives in their favor.

Chicago White Sox White Sox MLB Preview

The Chicago White Sox arrive in Seattle for their August 6 matchup at T‑Mobile Park with a 42‑70 record but carry unexpected betting credibility thanks to a 17‑15 ATS mark as road underdogs and a strong 14‑11 run‑line record in Wednesday games, making them one of the few teams with situational momentum even in a series finale as underdogs. Jonathan Cannon gets the start for Chicago, holding a 4‑8 record with a 4.77 ERA, yet showcasing impressive command metrics including walk rates under 2 BB/9, a barrel rate under 10 percent, and average exit velocity under 90 mph—qualities that help him suppress damage even without high strikeout totals, especially in a park like Seattle where contact is more han­dled than launching. The White Sox lineup has shown unexpected competitiveness post–All‑Star break, led by Colson Montgomery, who surged into league‑leader status in RBIs during the stretch, complemented by Lenyn Sosa’s on‑base discipline and Luis Robert Jr.’s power and speed elements. Their offensive identity is built on disciplined plate coverage, situational patience, and aggressive base running—tools that force counts and challenge pitchers like Bryan Woo to execute precisely.

Defensively, Chicago boasts improved athleticism in the infield and outfield coupled with high double‑play conversion efficiency, which supports Cannon’s contact‑oriented style by turning well‑struck balls into outs and limiting Seattle’s middle‑lineup impact. The bullpen has held up well in recent road outings, successfully bridging six‑inning starts with low inherited‑run damage, and has shown flexibility in matchup deployment. In terms of betting value, Chicago’s ATS profile—especially its road tendencies and mid‑week reliability—makes +1.5 on the run line an attractive contrarian leg, even in a matchup where win totals suggest Seattle. If Cannon limits walks, the offense continues manufacturing runs via patient at‑bats and situational hitting, and the bullpen preserves small margins, the White Sox have runway to push this game into the seventh trailing by a single run or even emerge with a narrow win. Though Seattle enters as a strong moneyline choice thanks to Bryan Woo’s elite season, backing the White Sox at +1.5 offers leverage: a disciplined, resilient team capable of covering tight lines and possibly surprising if Seattle’s bullpen wears down or Woo shows cracks under pressure.

The Chicago White Sox visit T-Mobile Park to face the Seattle Mariners on August 6, 2025, with first pitch scheduled around 9:40 PM ET. Seattle enters as a clear favorite—about –1.5 on the run line and –130 on the moneyline—with total runs projected near 7.5 in what appears to be a spot favoring the hosts. Chicago White Sox vs Seattle AI Prediction: Free MLB Betting Insights for Aug 06. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Seattle Mariners MLB Preview

The Seattle Mariners step onto their home turf at T‑Mobile Park on August 6 with a 61–53 record, offering both high-powered home offense and dominant run-line kudos despite covering just 42 percent of games this season—a contradiction highlighting their tendency to win tight contests without covering spreads; they are favored by roughly –1.5 on the run line and roughly –258 on the moneyline, though bettors should remain cautious given their history on the ATS ledger. The commanding presence on the hill belongs to right‑hander Bryan Woo, who enters with a sterling 3.11 ERA, 0.97 WHIP, and 127 strikeouts over 133 innings—metrics landing him among MLB’s most efficient starters and giving Seattle a major edge in strikeout-to-walk control, particularly against contact-based lineups like Chicago’s. Woo has been historically successful against the White Sox this week, allowing just one earned run through seven innings in the previous game while leading the Mariners to an 8–3 win—a performance that underscores his ability to suppress opposing offenses and set a dominant tempo.

At the plate, Seattle relies on powerful middle-order bats in Cal Raleigh, who leads MLB with 42 home runs and ranks among the top in slugging; Eugenio Suárez and Josh Naylor offer RBI depth, while Julio Rodríguez and Randy Arozarena bring speed and gap power to round out a potent lineup even if batting averages have dipped since the All-Star break. The Mariners’ bullpen remains solid, supporting Woo with reliable late-inning arms, and while their recent home ATS performance has been inconsistent, their pitching depth and offensive upside still favor them heavily in moneyline play. Defensively, Seattle fields a strong unit that converts double plays efficiently and supports high-contact pitching with range and fundamental precision, helping mitigate threats that stem from well-placed bunts or situational base running. For bettors, the Mariners’ best value lies in a moneyline hold—even as favorites—given Woo’s dominance, home crowd leverage, and offensive balance; the narrow run-line spread may be problematic given Seattle’s ATS struggles, but their ability to win outright comfortably remains plausible. The matchup hinges on Woo executing early, preventing Chicago from stringing together hits around leadoffs by hitters like Colson Montgomery, and whether their bullpen can hold a lead if the game remains close into the later innings. In sum, while Seattle may not cover consistently ATS, their talent and home comfort give them clear edge over the struggling Sox—making them the logical pick for outright victory, though the spread may be a savvy fade depending on how the line opens and market sentiment.

Chicago White Sox vs. Seattle Prop Picks (AI)

AI algorithm Remi is pouring through loads of datapoints on each player. In fact, anytime the White Sox and Mariners play there’s always several intriguing observations to key in on. Not to mention games played at T-Mobile Park in Aug can often follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: L. Robert over 5 Fantasy Score.

Chicago White Sox vs. Seattle Prediction (AI)

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Remi, our AI sports genius, has been pouring over exorbitant amounts of data from every facet between the White Sox and Mariners and using recursive machine learning and kick-ass AI to crunch the data to a single cover probability.

Interestingly enough, the data has been most keyed in on the linear correlation of emphasis human bettors tend to put on Chicago White Sox’s strength factors between a White Sox team going up against a possibly deflated Mariners team. In reality, the true game analytics appear to reflect a strong lean against one Vegas line specifically.

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Below is our current AI Chicago White Sox vs Seattle picks, computer picks White Sox vs Mariners, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
MLB 9/26 DET@BOS UNLOCK THIS PICK 5 EXECUTIVE Locked EXECUTIVE
MLB 9/26 BAL@NYY UNLOCK THIS PICK 4 INTEL Locked INTEL
MLB 9/26 ARI@SD UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
MLB 9/26 NYM@MIA UNLOCK THIS PICK 1 INTEL Locked INTEL
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MLB 9/26 COL@SF UNLOCK THIS PICK 0 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

White Sox Betting Trends

Chicago is carrying a modest 20–17 overall record against the run line in 2025, but that splits into a 17–15 mark on the road, showing they’ve been slightly above .500 as visitors recently.

Mariners Betting Trends

Seattle has struggled in ATS markets this season with a 42 percent cover rate, making them one of MLB’s least reliable home favorites.

White Sox vs. Mariners Matchup Trends

Despite their poor overall ATS numbers, Chicago has a 14–11 ATS record in their last 25 Wednesday games, indicating their ability to stay competitive mid‑week.

Chicago White Sox vs. Seattle Game Info

Chicago White Sox vs Seattle starts on August 06, 2025 at 9:40 PM EST.

Spread: Seattle -1.5
Moneyline: Chicago White Sox +213, Seattle -264
Over/Under: 7.5

Chicago White Sox: (42-71)  |  Seattle: (61-53)

Remi's searched hard and found the best prop for this matchup: L. Robert over 5 Fantasy Score.. Prices move—always shop for the best number.

Despite their poor overall ATS numbers, Chicago has a 14–11 ATS record in their last 25 Wednesday games, indicating their ability to stay competitive mid‑week.

CHW trend: Chicago is carrying a modest 20–17 overall record against the run line in 2025, but that splits into a 17–15 mark on the road, showing they’ve been slightly above .500 as visitors recently.

SEA trend: Seattle has struggled in ATS markets this season with a 42 percent cover rate, making them one of MLB’s least reliable home favorites.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

Chicago White Sox vs. Seattle Odds

Remi is pouring through tons of stats on each player. In fact, anytime the Chicago White Sox vs Seattle trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme travel distance almost always follow normal, predictable patterns.

Chicago White Sox vs Seattle Opening Odds

CHW Moneyline: +213
SEA Moneyline: -264
CHW Spread: +1.5
SEA Spread: -1.5
Over/Under: 7.5

Chicago White Sox vs Seattle Live Odds

Games PTS ML SPR O/U
Sep 27, 2025 1:06PM EDT
Baltimore Orioles
New York Yankees
9/27/25 1:06PM
Orioles
Yankees
+190
-235
+1.5 (-105)
-1.5 (-115)
O 8.5 (-120)
U 8.5 (+100)
Sep 27, 2025 2:21PM EDT
St Louis Cardinals
Chicago Cubs
9/27/25 2:21PM
Cardinals
Cubs
 
-175
 
-1.5 (+115)
O 9.5 (-105)
U 9.5 (-115)
Sep 27, 2025 3:09PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/27/25 3:09PM
Rays
Blue Jays
+135
-165
+1.5 (-165)
-1.5 (+135)
O 8.5 (+100)
U 8.5 (-120)
Sep 27, 2025 4:06PM EDT
Chicago White Sox
Washington Nationals
9/27/25 4:06PM
White Sox
Nationals
+100
-120
-1.5 (+155)
+1.5 (-190)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 4:06PM EDT
Colorado Rockies
San Francisco Giants
9/27/25 4:06PM
Rockies
Giants
+185
-225
+1.5 (-110)
-1.5 (-110)
O 8 (-105)
U 8 (-115)
Sep 27, 2025 4:11PM EDT
New York Mets
Miami Marlins
9/27/25 4:11PM
Mets
Marlins
-130
+110
-1.5 (+125)
+1.5 (-150)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
+170
-205
+1.5 (-120)
-1.5 (+100)
O 8.5 (-115)
U 8.5 (-105)
Sep 27, 2025 6:12PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 6:12PM
Rangers
Guardians
+135
-165
+1.5 (-170)
-1.5 (+140)
O 7 (-120)
U 7 (+100)
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
+125
-150
+1.5 (-175)
-1.5 (+145)
O 8 (-105)
U 8 (-115)
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
+140
-170
+1.5 (-165)
-1.5 (+135)
O 8 (-115)
U 8 (-105)
Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
+115
-140
+1.5 (-190)
-1.5 (+155)
O 7.5 (-115)
U 7.5 (-105)
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
+105
-125
+1.5 (-205)
-1.5 (+170)
O 7.5 (-110)
U 7.5 (-110)
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
-105
-115
-1.5 (+150)
+1.5 (-180)
O 10 (-110)
U 10 (-110)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Chicago White Sox White Sox vs. Seattle Mariners on August 06, 2025 at T-Mobile Park.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS
CIN@ARI KEBRYAN HAYES STRIKEOUTS UNDER 0.5 56.2% 6 WIN
LAD@SD SD +110 50.9% 6 WIN