Orioles vs. Guardians
Prediction, Odds & Props
Jul 24 | MLB AI Picks

Updated: 2025-07-22T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Baltimore Orioles (44–57) will visit the Cleveland Guardians (51–50) at Progressive Field on July 24, 2025—both teams sit just below .500 but Cleveland enters in better form. The Guardians are favored at home, with both clubs looking to maintain momentum as the All-Star break snap fades.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Jul 24, 2025

Start Time: 1:10 PM EST​

Venue: Progressive Field​

Guardians Record: (51-50)

Orioles Record: (44-57)

OPENING ODDS

BAL Moneyline: -101

CLE Moneyline: -119

BAL Spread: -1.5

CLE Spread: +1.5

Over/Under: 9

BAL
Betting Trends

  • Baltimore has been strong against the spread, going 8–3 ATS in their last 11 games.

CLE
Betting Trends

  • Cleveland has also been solid, posting a 7–4 ATS record over their last 11 contests.

MATCHUP TRENDS

  • Over their last 10 games, the Guardians have gone 7–3–0 ATS, while Baltimore has hit the over/under just 4 times in 11—indicating more tightly contested affairs when Cleveland is involved.

BAL vs. CLE
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: J. Holliday over 5.5 Fantasy Score.

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Baltimore vs Cleveland Prediction & Odds:
Free MLB Betting Insights for 7/24/25

The final game of this four-game series between the Baltimore Orioles and Cleveland Guardians at Progressive Field on July 24, 2025, arrives with intriguing momentum and betting implications, as both teams are trending positively against the spread despite differing standings. The Guardians, now 51–50 and hovering right around .500, have found renewed form in July, winning four straight games heading into this contest and taking the first two games of this series in convincing fashion. Their offense, powered by José Ramírez, Josh Naylor, and emerging rookie Kyle Manzardo, has produced timely hits while their bullpen has been quietly dominant, especially in the late innings with Emmanuel Clase and Aroldis Chapman closing the door. On the other side, the Orioles enter at 44–57 but have covered in eight of their last eleven, demonstrating their grit and competitiveness even while often slotted as underdogs. Interim manager Tony Mansolino has breathed new life into the lineup since taking over in mid-May, with Gunnar Henderson and Dylan Carlson showing leadership at the plate, and Tyler O’Neill proving to be a valuable midseason addition with both bat and glove. Baltimore’s pitching remains a mixed bag, but their bullpen, led by Andrew Kittredge and Tomoyuki Sugano, has improved their ability to stay within striking distance late in games. In terms of advanced betting stats, the Guardians have gone 7–3 against the spread in their last 10 games, consistently covering the line, while the Orioles’ recent form includes several one-run losses or close covers, making them dangerous in spread betting.

This contest may come down to who performs better with runners in scoring position, an area where Cleveland has outperformed Baltimore over the past month. The Guardians’ home advantage at Progressive Field, where their pitchers are generally more effective and the park’s spacious outfield limits home runs, slightly tilts the matchup in their favor. However, the Orioles have been sneakily effective on the road against the spread and are playing with the confidence of a team trying to rebuild its identity under new leadership. Expect Cleveland to remain aggressive early, leaning on Ramírez and Steven Kwan to set the table, while Baltimore may counter with speed and situational hitting from Jordan Westburg and Ryan Mountcastle. Defensively, both clubs are fairly sound, but Cleveland has the edge in late-game bullpen usage and overall game management, especially in close situations. With both teams trending above average ATS and totals markets leaning toward the over in Cleveland games, this series finale is likely to remain tight, with key matchups in the sixth through ninth innings potentially deciding the outcome. While Cleveland’s current form and home dominance make them favorites, Baltimore’s ATS value as an underdog in tight games cannot be dismissed. It’s a classic late-July matchup between a team looking to climb into playoff contention and another trying to avoid a full rebuild, and both sides have something to prove before the trade deadline. The game shapes up as a potential low-to-mid scoring contest decided by bullpen execution, timely hitting, and perhaps a single miscue in the field or on the basepaths.

Baltimore Orioles MLB Preview

The Baltimore Orioles arrive at Progressive Field for the series finale against the Cleveland Guardians with a 44–57 record that belies the competitiveness they’ve shown in recent weeks, particularly against the spread. While the team has struggled to climb out of the AL East basement, they have shown significant improvement in July under interim manager Tony Mansolino, who took over in mid-May and has since instilled a more focused, aggressive, and resilient approach. Baltimore has gone 6–5 so far in July and an impressive 8–3 against the spread in their last 11 games, a sign that while they may not always win outright, they consistently keep games close, providing value for bettors and frustrating opponents. Key to their recent competitiveness has been the resurgence of Gunnar Henderson, who has found his stride both offensively and defensively and is now setting the tone for the lineup alongside Dylan Carlson and midseason acquisition Tyler O’Neill. O’Neill’s mix of power and veteran savvy has given the Orioles a much-needed boost in the middle of the order, while Jordan Westburg and Adley Rutschman continue to develop into reliable young contributors capable of changing the momentum of games. Pitching remains Baltimore’s most volatile area, with the rotation offering inconsistent outings that put pressure on the bullpen, but the relief corps led by Andrew Kittredge and Japanese veteran Tomoyuki Sugano has held up surprisingly well. Both relievers have shown an ability to neutralize late-inning threats, and their performance will be crucial in Cleveland, where the Guardians tend to capitalize on late rallies.

The Orioles’ strategy will likely involve small ball, aggressive baserunning, and manufacturing runs rather than relying on the long ball, especially in the spacious outfield of Progressive Field that tends to suppress home runs. Defensively, the Orioles have been average overall, but improved communication and shifts in late innings have helped them remain in close games, which is essential for a team that thrives on staying within the spread. Their head-to-head record against Cleveland entering this series stood at 2–1, showing they’re capable of stealing games from a more consistent Guardians squad, especially when their offense is clicking and their bullpen holds steady. Baltimore has nothing to lose and is playing with a chip on its shoulder, which makes them particularly dangerous as road underdogs. They’ve been able to hang around games even when trailing early and have outperformed expectations when playing as away underdogs in recent weeks. While their playoff hopes may be distant, the team has embraced its spoiler role and is leaning into developmental opportunities with a focus on building for 2026, meaning players like Henderson, Rutschman, and Grayson Rodriguez are gaining valuable experience in high-leverage moments. For bettors, Baltimore’s knack for keeping games close and covering the run line even in losses is a key trend, and with momentum and energy shifting in the clubhouse under Mansolino, this is not the same Orioles team from April or May. Their combination of grit, emerging talent, and bullpen stability suggests they will remain competitive deep into this matchup, and possibly push Cleveland to the edge once again in a game that is far from a guaranteed win for the home team.

The Baltimore Orioles (44–57) will visit the Cleveland Guardians (51–50) at Progressive Field on July 24, 2025—both teams sit just below .500 but Cleveland enters in better form. The Guardians are favored at home, with both clubs looking to maintain momentum as the All-Star break snap fades. Baltimore vs Cleveland AI Prediction: Free MLB Betting Insights for Jul 24. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Cleveland Guardians MLB Preview

The Cleveland Guardians enter the final game of this four-game series against the Baltimore Orioles at Progressive Field riding a wave of midseason momentum and playing some of their best baseball of the year, currently sitting at 51–50 and flirting with a climb above .500 for the first time in months. Winners of four straight and 8 of their last 10, the Guardians are not only winning outright but covering spreads consistently as well, going 7–3 ATS over that stretch and showing improvement in virtually every facet of the game. Their offense has turned a corner in July, with José Ramírez leading the charge once again as the team’s heart and soul, batting over .290 with power and timely hits, while first baseman Josh Naylor has provided key protection behind him in the lineup. Steven Kwan continues to set the table effectively from the leadoff spot, showcasing exceptional contact skills and on-base percentage, and rookie Kyle Manzardo has added a youthful spark that keeps opposing pitchers honest. Manager Stephen Vogt has impressed in his first season, demonstrating strong bullpen management and maximizing matchups late in games, which has made the Guardians particularly dangerous in tight contests. The pitching staff, led by Logan Allen and Tanner Bibee in the rotation, has benefited from deeper support, while the back-end bullpen duo of Emmanuel Clase and Aroldis Chapman gives Cleveland one of the most fearsome closing tandems in baseball, especially when holding a lead after the sixth inning.

Defensively, Cleveland remains solid and reliable, particularly in the infield with Andrés Giménez flashing Gold Glove potential and limiting opponents’ run-scoring opportunities with clutch double plays and rangy stops. Progressive Field continues to be a strong home-field advantage, especially in lower-scoring contests where crowd energy amplifies tension in late innings and helps the Guardians thrive in one-run games. Against a Baltimore team that has struggled overall but remains scrappy and competitive, the Guardians must stay disciplined and not underestimate a club that has covered in eight of its last eleven and can pounce on mistakes. Cleveland has shown the ability to win in multiple ways—whether by putting up a crooked number early, scratching out runs with bunts and sac flies, or grinding out wins via the bullpen. That versatility will be crucial in this matchup, where scoring may come at a premium and situational hitting could determine the outcome. The Guardians’ recent series wins have come thanks to strong starts and back-end bullpen execution, and replicating that formula again could result in a fifth straight win and a step closer to solidifying their place in the playoff race. ATS-wise, Cleveland has covered frequently in similar matchups this year, particularly at home when favored, and their current stretch of high-level baseball suggests they are hitting their stride at the right time. With confidence high, offense improving, and pitching tightening up, the Guardians have a chance to finish this series strong, further assert their home-field edge, and continue their steady ascent in the AL Central standings.

Baltimore vs. Cleveland Prop Picks (AI)

AI algorithm Remi is pouring through loads of stats on each player. In fact, anytime the Orioles and Guardians play there’s always several intriguing observations to key in on. Not to mention games played at Progressive Field in Jul almost always follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: J. Holliday over 5.5 Fantasy Score.

Baltimore vs. Cleveland Prediction (AI)

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Remi, our AI sports wizard, has been pouring over exorbitant amounts of data from every past game between the Orioles and Guardians and using recursive machine learning and cutting-edge AI to crunch the data to a single cover probability.

Oddly enough, we’ve seen the AI has been most keyed in on the growing factor knucklehead sportsbettors often put on player performance factors between a Orioles team going up against a possibly tired Guardians team. In reality, the true game analytics appear to reflect a slight lean against one Vegas line specifically.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI Baltimore vs Cleveland picks, computer picks Orioles vs Guardians, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
MLB 9/26 DET@BOS UNLOCK THIS PICK 5 EXECUTIVE Locked EXECUTIVE
MLB 9/26 BAL@NYY UNLOCK THIS PICK 4 INTEL Locked INTEL
MLB 9/26 ARI@SD UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
MLB 9/26 NYM@MIA UNLOCK THIS PICK 1 INTEL Locked INTEL
MLB 9/26 NYM@MIA GET FREE PICK NOW 1
MLB 9/26 COL@SF UNLOCK THIS PICK 0 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

Orioles Betting Trends

Baltimore has been strong against the spread, going 8–3 ATS in their last 11 games.

Guardians Betting Trends

Cleveland has also been solid, posting a 7–4 ATS record over their last 11 contests.

Orioles vs. Guardians Matchup Trends

Over their last 10 games, the Guardians have gone 7–3–0 ATS, while Baltimore has hit the over/under just 4 times in 11—indicating more tightly contested affairs when Cleveland is involved.

Baltimore vs. Cleveland Game Info

Baltimore vs Cleveland starts on July 24, 2025 at 1:10 PM EST.

Spread: Cleveland +1.5
Moneyline: Baltimore -101, Cleveland -119
Over/Under: 9

Baltimore: (44-57)  |  Cleveland: (51-50)

Remi's searched hard and found the best prop for this matchup: J. Holliday over 5.5 Fantasy Score.. Prices move—always shop for the best number.

Over their last 10 games, the Guardians have gone 7–3–0 ATS, while Baltimore has hit the over/under just 4 times in 11—indicating more tightly contested affairs when Cleveland is involved.

BAL trend: Baltimore has been strong against the spread, going 8–3 ATS in their last 11 games.

CLE trend: Cleveland has also been solid, posting a 7–4 ATS record over their last 11 contests.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

Baltimore vs. Cleveland Odds

AI algorithm Remi is pouring through tons of data on each player. In fact, anytime the Baltimore vs Cleveland trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme altitude can often follow normal, predictable patterns.

Baltimore vs Cleveland Opening Odds

BAL Moneyline: -101
CLE Moneyline: -119
BAL Spread: -1.5
CLE Spread: +1.5
Over/Under: 9

Baltimore vs Cleveland Live Odds

Games PTS ML SPR O/U
Sep 27, 2025 1:06PM EDT
Baltimore Orioles
New York Yankees
9/27/25 1:06PM
Orioles
Yankees
+194
-235
+1.5 (-105)
-1.5 (-114)
O 8.5 (-122)
U 8.5 (+100)
Sep 27, 2025 2:21PM EDT
St Louis Cardinals
Chicago Cubs
9/27/25 2:21PM
Cardinals
Cubs
 
-168
 
-1.5 (+118)
O 9 (-122)
U 9 (+100)
Sep 27, 2025 3:09PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/27/25 3:09PM
Rays
Blue Jays
+132
-156
+1.5 (-154)
-1.5 (+128)
O 8.5 (-106)
U 8.5 (-114)
Sep 27, 2025 4:06PM EDT
Chicago White Sox
Washington Nationals
9/27/25 4:06PM
White Sox
Nationals
+102
-120
-1.5 (+162)
+1.5 (-196)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 4:06PM EDT
Colorado Rockies
San Francisco Giants
9/27/25 4:06PM
Rockies
Giants
+198
-240
+1.5 (-110)
-1.5 (-110)
O 8 (-108)
U 8 (-112)
Sep 27, 2025 4:11PM EDT
New York Mets
Miami Marlins
9/27/25 4:11PM
Mets
Marlins
-124
+106
-1.5 (+130)
+1.5 (-156)
O 8.5 (-112)
U 8.5 (-108)
Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
+177
-197
+1.5 (-118)
-1.5 (-102)
O 8.5 (-118)
U 8.5 (-102)
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
+128
-152
+1.5 (-178)
-1.5 (+146)
O 7.5 (-120)
U 7.5 (-102)
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
+143
-158
+1.5 (-150)
-1.5 (+130)
O 8.5 (+100)
U 8.5 (-120)
Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
+132
-156
+1.5 (-172)
-1.5 (+142)
O 7 (-120)
U 7 (-102)
Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
+120
-132
+1.5 (-180)
-1.5 (+157)
O 7.5 (-115)
U 7.5 (-105)
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
+102
-120
+1.5 (-215)
-1.5 (+180)
O 7.5 (-110)
U 7.5 (-110)
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
+104
-115
+1.5 (-185)
-1.5 (+161)
O 10 (-110)
U 10 (-110)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Baltimore Orioles vs. Cleveland Guardians on July 24, 2025 at Progressive Field.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS
CIN@ARI KEBRYAN HAYES STRIKEOUTS UNDER 0.5 56.2% 6 WIN
LAD@SD SD +110 50.9% 6 WIN