Cardinals vs. Rockies
Prediction, Odds & Props
Jul 23 | MLB AI Picks

Updated: 2025-07-21T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The St. Louis Cardinals (52–50) head to Coors Field to face the Colorado Rockies (25–76) on Wednesday, July 23. The Cardinals are strong favorites around –193 on the moneyline, with an over/under set at 11 runs—suggesting a tilt toward offense in a hitter-friendly environment.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Jul 23, 2025

Start Time: 3:10 PM EST​

Venue: Coors Field​

Rockies Record: (25-76)

Cardinals Record: (52-50)

OPENING ODDS

STL Moneyline: -193

COL Moneyline: +160

STL Spread: -1.5

COL Spread: +1.5

Over/Under: 11

STL
Betting Trends

  • St. Louis has struggled on the road this month, going just 1–6 ATS away in July.

COL
Betting Trends

  • Colorado has suffered through a rough home stretch under interim manager Schaeffer, continuing a performance slump that leaves them without momentum at Coors Field.

MATCHUP TRENDS

  • Cardinals-Rockies games at Coors have historically swung high, but eight of the last ten matchups have stayed under the total—highlighting that even at Coors, pitching and situational play often prevail.

STL vs. COL
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: A. Burleson under 2.5 Total Bases.

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St. Louis vs Colorado Prediction & Odds:
Free MLB Betting Insights for 7/23/25

The upcoming matchup between the St. Louis Cardinals and Colorado Rockies on July 23, 2025, at Coors Field offers a stark contrast between two teams heading in opposite directions. The Cardinals enter the game in the thick of the NL Wild Card hunt, aiming to bank crucial wins against one of the league’s weakest clubs, while the Rockies continue to endure one of the most dismal seasons in franchise history, firmly entrenched at the bottom of the standings. St. Louis will send right-hander Andre Pallante to the mound, a pitcher who has delivered serviceable outings through midseason, despite a mid-4.00 ERA. He’s shown flashes of excellence, particularly when locating his sinker and inducing ground balls—an essential skill in the altitude of Coors Field. Opposite him, Colorado counters with lefty Austin Gomber, who has had an erratic 2025 campaign and often struggles with command, which could spell trouble against a Cardinals lineup that boasts the likes of Nolan Arenado, Willson Contreras, Paul Goldschmidt, and Brendan Donovan. Offensively, the Cardinals have found more consistency recently with timely hitting and improved OBP from the top of the order, while their bullpen remains one of the more reliable in the NL thanks to the likes of JoJo Romero and Ryan Helsley.

Meanwhile, the Rockies have been in a deep funk, struggling to produce runs even at home. They’ll rely on Hunter Goodman, Michael Toglia, and Ezequiel Tovar for offensive spark, though injuries and inconsistency have plagued their efforts. Colorado’s bullpen has been one of the worst in the majors statistically, and the team’s defensive lapses have only compounded their woes. The venue adds another variable—Coors Field is known for offense, but in recent years matchups between these two teams have often gone under the total, suggesting pitching matchups and game management may matter more than ballpark reputation. This tilt looks like a prime opportunity for the Cardinals to secure a road win, especially if Pallante can work into the middle innings and St. Louis can avoid bullpen overuse. While no game in Denver is ever a lock given the unique altitude challenges, the Cardinals hold clear edges in starting pitching, bullpen reliability, lineup depth, and overall momentum. For bettors and fans, the under may be worth considering despite the location, particularly with recent totals history and both starters aiming to manage contact and innings. Expect the Cardinals to play with urgency as they continue to fight for playoff relevance, while the Rockies try to salvage pride in a season long gone awry.

St. Louis Cardinals MLB Preview

The St. Louis Cardinals enter this matchup against the Colorado Rockies looking to build on a stretch of more competitive baseball as they try to claw their way into postseason relevance in the National League. While their overall record has been inconsistent through much of the 2025 campaign, the Cardinals have steadily improved since the All-Star break, aided by better bullpen performances and more consistent situational hitting. Much of their recent success can be attributed to the emergence of young contributors like Masyn Winn and Alec Burleson, who have given the lineup an infusion of energy and production in key moments. Andre Pallante gets the start for St. Louis in this one, and while he hasn’t been dominant, his pitch-to-contact approach could be well-suited for Coors Field if he’s able to keep the ball down and avoid barrels. The Cardinals have been careful in managing his innings and matching him up against more beatable lineups, and facing a struggling Rockies team presents a favorable opportunity. The middle of the Cardinals’ lineup continues to be anchored by Paul Goldschmidt and Nolan Arenado, both of whom have maintained productive, if not elite, offensive campaigns.

Brendan Donovan has added versatility with his ability to slot into multiple spots both defensively and atop the batting order, while Willson Contreras provides the kind of power threat and veteran experience St. Louis will rely on heavily down the stretch. One of the keys to their recent turnaround has been bullpen stability, with JoJo Romero and Ryan Helsley anchoring the back end, giving them confidence to protect late leads. Defensively, the Cardinals remain solid if unspectacular, but their infield efficiency has helped offset some of the contact-heavy pitching. Heading into a hitter-friendly environment like Coors Field, the Cardinals will aim to strike early against Austin Gomber, a pitcher they know well from his St. Louis days, and whose command issues could lead to long innings and scoring opportunities. With playoff contention still within reach, every series—especially against struggling opponents—carries heightened importance. If the Cardinals are able to maintain recent momentum and execute effectively in high-leverage spots, this game presents a critical chance to secure a needed road win. The challenge, as always in Denver, will be to keep composure in a ballpark where no lead is safe, but with a more complete and focused roster, St. Louis has every reason to enter this matchup with confidence and a sense of urgency.

The St. Louis Cardinals (52–50) head to Coors Field to face the Colorado Rockies (25–76) on Wednesday, July 23. The Cardinals are strong favorites around –193 on the moneyline, with an over/under set at 11 runs—suggesting a tilt toward offense in a hitter-friendly environment. St. Louis vs Colorado AI Prediction: Free MLB Betting Insights for Jul 23. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Colorado Rockies MLB Preview

The Colorado Rockies return home to Coors Field on July 23, 2025, to face the St. Louis Cardinals in a matchup that highlights two teams on very different competitive paths. For the Rockies, the 2025 season has largely been about player development and identifying long-term building blocks, as their record continues to reflect the challenges of rebuilding in a hitter-friendly environment that demands depth both on the mound and in the lineup. Colorado’s struggles this year have centered on inconsistent starting pitching and a bullpen that’s been among the league’s worst in preventing late-game scoring. Austin Gomber, a former Cardinal, takes the mound for this game and will aim to exact some revenge against his old club. Gomber’s season has been a rollercoaster—he’s had strong outings at times, but more often than not he’s struggled with command and home run suppression, particularly at Coors. Still, when he’s able to locate his curveball and mix speeds effectively, he’s capable of neutralizing right-handed bats, and Colorado will be hoping for one of those better versions of Gomber to show up. Offensively, the Rockies remain anchored by veterans like Kris Bryant and Ryan McMahon, both of whom have shown flashes of power and production, though neither has fully lived up to their billing this season. Youngsters like Ezequiel Tovar and Brenton Doyle continue to gain valuable experience, with Tovar especially earning praise for his defensive instincts and potential as a future cornerstone at shortstop.

Offense tends to come easier in Denver, and the Rockies are always a threat to string together runs, particularly in the thin air where mistakes are magnified and extra-base hits come in bunches. However, their biggest obstacle remains preventing those same big innings from opponents, and the bullpen’s inability to strand inherited runners has been a consistent theme. Defensively, Colorado has been solid in the infield but remains vulnerable in the outfield gaps, an issue that is frequently exposed by lineups that work counts and drive the ball with authority. Manager Bud Black has done his best to manage innings and workloads for his young arms, but attrition has taken its toll over the long summer months. This matchup against a streaky but dangerous Cardinals squad will test the Rockies’ ability to execute early and maintain focus late, especially if the game turns into a high-scoring affair. Playing spoiler is now the Rockies’ primary motivation, and they’ll look to capitalize on any lapses by a St. Louis team fighting to stay in the playoff picture. For Colorado, small victories—like a quality start from Gomber or a multi-hit night from a rising prospect—represent meaningful progress in a season centered more on evaluation than postseason dreams. But with the comfort of playing at home and the unpredictability of Coors Field always in play, the Rockies are never to be completely counted out, particularly when facing a familiar foe in front of their home fans.

St. Louis vs. Colorado Prop Picks (AI)

Remi is pouring through loads of stats on each team. In fact, anytime the Cardinals and Rockies play there’s always several intriguing observations to key in on. Not to mention games played at Coors Field in Jul rarely follow normal, predictable patterns.
Remi's searched hard and found the best prop for this matchup: A. Burleson under 2.5 Total Bases.

St. Louis vs. Colorado Prediction (AI)

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Remi, our AI sports wizard, has been pouring over millions of data from every past game between the Cardinals and Rockies and using recursive machine learning and kick-ass AI to examine the data to a single cover probability.

The Algorithm has been most keyed in on the growing weight knucklehead sportsbettors regularly put on player performance factors between a Cardinals team going up against a possibly improved Rockies team. We’ve found the true game analytics appear to reflect a slight lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI St. Louis vs Colorado picks, computer picks Cardinals vs Rockies, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
MLB 9/26 DET@BOS UNLOCK THIS PICK 5 EXECUTIVE Locked EXECUTIVE
MLB 9/26 BAL@NYY UNLOCK THIS PICK 4 INTEL Locked INTEL
MLB 9/26 ARI@SD UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
MLB 9/26 NYM@MIA UNLOCK THIS PICK 1 INTEL Locked INTEL
MLB 9/26 NYM@MIA GET FREE PICK NOW 1
MLB 9/26 COL@SF UNLOCK THIS PICK 0 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

Cardinals Betting Trends

St. Louis has struggled on the road this month, going just 1–6 ATS away in July.

Rockies Betting Trends

Colorado has suffered through a rough home stretch under interim manager Schaeffer, continuing a performance slump that leaves them without momentum at Coors Field.

Cardinals vs. Rockies Matchup Trends

Cardinals-Rockies games at Coors have historically swung high, but eight of the last ten matchups have stayed under the total—highlighting that even at Coors, pitching and situational play often prevail.

St. Louis vs. Colorado Game Info

St. Louis vs Colorado starts on July 23, 2025 at 3:10 PM EST.

Spread: Colorado +1.5
Moneyline: St. Louis -193, Colorado +160
Over/Under: 11

St. Louis: (52-50)  |  Colorado: (25-76)

Remi's searched hard and found the best prop for this matchup: A. Burleson under 2.5 Total Bases.. Prices move—always shop for the best number.

Cardinals-Rockies games at Coors have historically swung high, but eight of the last ten matchups have stayed under the total—highlighting that even at Coors, pitching and situational play often prevail.

STL trend: St. Louis has struggled on the road this month, going just 1–6 ATS away in July.

COL trend: Colorado has suffered through a rough home stretch under interim manager Schaeffer, continuing a performance slump that leaves them without momentum at Coors Field.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

St. Louis vs. Colorado Odds

Remi is pouring through mountains of data on each team. In fact, anytime the St. Louis vs Colorado trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme altitude almost always follow normal, predictable betting trends.

St. Louis vs Colorado Opening Odds

STL Moneyline: -193
COL Moneyline: +160
STL Spread: -1.5
COL Spread: +1.5
Over/Under: 11

St. Louis vs Colorado Live Odds

Games PTS ML SPR O/U
Sep 27, 2025 1:06PM EDT
Baltimore Orioles
New York Yankees
9/27/25 1:06PM
Orioles
Yankees
+194
-235
+1.5 (-105)
-1.5 (-114)
O 8.5 (-122)
U 8.5 (+100)
Sep 27, 2025 2:21PM EDT
St Louis Cardinals
Chicago Cubs
9/27/25 2:21PM
Cardinals
Cubs
 
-168
 
-1.5 (+118)
O 9 (-122)
U 9 (+100)
Sep 27, 2025 3:09PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/27/25 3:09PM
Rays
Blue Jays
+132
-156
+1.5 (-154)
-1.5 (+128)
O 8.5 (-106)
U 8.5 (-114)
Sep 27, 2025 4:06PM EDT
Chicago White Sox
Washington Nationals
9/27/25 4:06PM
White Sox
Nationals
+102
-120
-1.5 (+162)
+1.5 (-196)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 4:06PM EDT
Colorado Rockies
San Francisco Giants
9/27/25 4:06PM
Rockies
Giants
+198
-240
+1.5 (-110)
-1.5 (-110)
O 8 (-108)
U 8 (-112)
Sep 27, 2025 4:11PM EDT
New York Mets
Miami Marlins
9/27/25 4:11PM
Mets
Marlins
-124
+106
-1.5 (+130)
+1.5 (-156)
O 8.5 (-112)
U 8.5 (-108)
Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
+177
-197
+1.5 (-118)
-1.5 (-102)
O 8.5 (-118)
U 8.5 (-102)
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
+128
-152
+1.5 (-178)
-1.5 (+146)
O 7.5 (-120)
U 7.5 (-102)
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
+143
-158
+1.5 (-150)
-1.5 (+130)
O 8.5 (+100)
U 8.5 (-120)
Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
+132
-156
+1.5 (-172)
-1.5 (+142)
O 7 (-120)
U 7 (-102)
Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
+120
-132
+1.5 (-180)
-1.5 (+157)
O 7.5 (-115)
U 7.5 (-105)
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
+102
-120
+1.5 (-215)
-1.5 (+180)
O 7.5 (-110)
U 7.5 (-110)
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
+104
-115
+1.5 (-185)
-1.5 (+161)
O 10 (-110)
U 10 (-110)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers St. Louis Cardinals vs. Colorado Rockies on July 23, 2025 at Coors Field.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS
CIN@ARI KEBRYAN HAYES STRIKEOUTS UNDER 0.5 56.2% 6 WIN
LAD@SD SD +110 50.9% 6 WIN