Padres vs Marlins Prediction — AI Finds CAN'T MISS MLB Lines & Props (Jul 23)
Updated: 2025-07-21T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The San Diego Padres (56–47) head to loanDepot Park to face the Miami Marlins (48–55) on Wednesday, July 23. The Padres are slight favorites around –150 on the moneyline, with the total set at 8 runs, suggesting a competitive but moderately scoring contest.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Jul 23, 2025
Start Time: 12:10 PM EST
Venue: loanDepot park
Marlins Record: (47-53)
Padres Record: (55-46)
OPENING ODDS
SD Moneyline: -146
MIA Moneyline: +123
SD Spread: -1.5
MIA Spread: +1.5
Over/Under: 8
SD
Betting Trends
- San Diego has gone 23–27 on the road overall but been strong ATS as underdogs, covering in 9 of their past 11 away games when not favored, showing resilience even in tough territories.
MIA
Betting Trends
- Miami has struggled as moneyline favorites at home (-146 or shorter), dropping all four such games, and is just 22–28 at loanDepot Park—reflecting inconsistency in home performance.
MATCHUP TRENDS
- Despite the total, eight of the last ten Padres–Marlins matchups have gone over, indicating a strong pattern toward offense regardless of location or line.
SD vs. MIA
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: O. Lopez over 5 Fantasy Score.
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San Diego vs Miami Prediction & Odds:
Free MLB Betting Insights for 7/23/25
On the other side, the Marlins will look to young contributors like Otto Lopez, Jesús Sánchez, and Kyle Stowers to generate pressure, but inconsistency at the plate has made stringing together innings a challenge. The Marlins’ best shot may come in trying to disrupt Morejón early and then manufacture runs through aggressive base running, but if the Padres starter settles in, the game could lean heavily toward the visitors. Defensively, San Diego has played cleaner baseball, with better fielding metrics and fewer unforced errors, while the Marlins continue to search for a reliable defensive identity. With the total hovering at 8 and recent head-to-head matchups tending to the over, bettors might see another high-scoring affair, especially if Alcántara cannot go deep into the game. Both clubs will treat this contest as critical: the Padres to stay alive in a brutal NL West, and the Marlins to prevent slipping further into irrelevance in the East. Given the form, consistency, and depth advantage, San Diego enters with a meaningful edge, though Miami will be banking on home-field urgency and a surprise rebound from their embattled ace. This game promises intriguing contrasts—one team surging and confident, the other scraping for footing—and whether it ends in a close grind or a run-heavy blowout could hinge entirely on who controls the mound in the first five innings.
Otra Noche en Miami 🌴 pic.twitter.com/wObvZ226Ht
— San Diego Padres (@Padres) July 22, 2025
San Diego Padres MLB Preview
The San Diego Padres enter this July 23 matchup against the Miami Marlins with increasing momentum as they look to extend their push for a postseason berth in the National League. Under manager Mike Shildt, San Diego has weathered early-season inconsistency and is starting to string together a run of competitive baseball in July, thanks in large part to an improved pitching staff and timely hitting. The Padres’ offense has been bolstered by the acquisition of Luis Arráez, whose league-leading contact skills have complemented the star-studded core of Fernando Tatis Jr., Manny Machado, and Jake Cronenworth. While Tatis brings the power-speed combination that can change games, it has been the consistency of Arráez at the top of the lineup and the resurgence of Jurickson Profar that have added depth to an order now capable of generating rallies from multiple points. Adrián Morejón, expected to start, has become a critical piece in their rotation. The young lefty has stayed healthy this year and rewarded the Padres with a 3.59 ERA, showing increased maturity and command in his recent outings. His ability to limit hard contact and keep hitters off-balance with his off-speed arsenal has allowed San Diego to remain competitive even in low-scoring affairs. The bullpen has also turned a corner, with Robert Suarez and Yuki Matsui closing down games with increasing confidence.
The Padres’ defense ranks among the top third in the league, led by strong infield play and outfield range that has prevented extra-base hits in key spots. One area where San Diego still seeks improvement is with runners in scoring position—despite their talent, they’ve often left men on base. However, recent trends suggest they’re beginning to convert more of those opportunities, especially on the road. Their series win over the Mets and competitive showings against division rivals have restored belief in the clubhouse, and this trip to Miami is seen as a prime opportunity to capitalize on a struggling opponent. Historically, the Padres have performed well at loanDepot Park, and with their current form, confidence will be high to extend that success. With Morejón providing a stable presence on the mound and their offense clicking in key moments, the Padres will aim to apply pressure early and not allow Miami to stay in the game late. This matchup gives San Diego a clear opportunity to gain ground in the National League Wild Card standings and further solidify themselves as a second-half threat. As the Padres eye a sweep or series win in Miami, this game could serve as a statement of intent that their playoff ambitions remain very much alive.

Credit: USA TODAY/IMAGN
Miami Marlins MLB Preview
The Miami Marlins enter their July 23 matchup against the San Diego Padres looking to snap out of an extended slump that has defined much of their 2025 season. Under the guidance of manager Skip Schumaker, the Marlins have continued to struggle with consistency on both sides of the ball, particularly with a lineup that has lacked timely production and a rotation decimated by injuries. Miami sits near the bottom of the National League standings and has been unable to build sustained momentum, especially at home where their offense has too often gone quiet. Josh Bell and Bryan De La Cruz remain central figures in the lineup, but their impact has been streaky, and the team as a whole has ranked among the lowest in MLB in key categories such as slugging percentage and OPS. One of the biggest storylines for the Marlins this season has been the regression of what was once a promising rotation. Eury Pérez remains sidelined, and with Jesús Luzardo and Edward Cabrera both having spent time on the IL, the Marlins have had to patch together starts with bullpen arms and depth call-ups. Trevor Rogers is expected to take the mound against San Diego, and while he has shown flashes of his former self, he’s struggled to string together consistent quality outings, often running into trouble by the fourth or fifth inning. His ERA has hovered above 4.80, and his control has been a concern, particularly against teams with strong on-base skills like the Padres.
The bullpen, led by Tanner Scott and Andrew Nardi, has had to shoulder a heavier load and has worn down as the season has progressed, particularly in close games where the offense has failed to support them. Defensively, the Marlins have been sound, especially with Jazz Chisholm Jr. providing versatility in the outfield and infield, but defensive efficiency alone hasn’t been enough to turn losses into wins. The biggest challenge for Miami in this matchup will be manufacturing offense against Adrián Morejón, a lefty who has kept opposing bats quiet in recent starts. Miami’s lineup, which leans heavily on right-handed power, has had difficulty adjusting to high-velocity southpaws, and unless Bell or De La Cruz can break through early, the team may find itself once again playing from behind. The Marlins’ recent home record has been poor, and while they’ve shown occasional signs of resilience, those moments have been too fleeting to shift the broader narrative of a lost season. With playoff hopes all but extinguished, this series against the Padres is less about standings and more about developing the young talent on the roster, establishing consistency in approach, and trying to play spoiler against a contending opponent. Miami’s path to victory will require a clean start from Rogers, improved situational hitting, and a bullpen that doesn’t crack under pressure—no small task against a Padres team currently playing with urgency and confidence.
Wiami Warlins pic.twitter.com/Y77594Ahgq
— Miami Marlins (@Marlins) July 23, 2025
San Diego vs. Miami Prop Picks (AI)
San Diego vs. Miami Prediction (AI)

Remi, our AI sports genius, has been pouring over mountains of data from every angle between the Padres and Marlins and using recursive machine learning and cutting-edge AI to analyze the data to a single cover probability.
Remi has been most watching on the linear correlation of factor knucklehead sportsbettors tend to put on player performance factors between a Padres team going up against a possibly unhealthy Marlins team. Trends look to say the true game analytics appear to reflect a strong lean against one Vegas line specifically.
Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.
Below is our current AI San Diego vs Miami picks, computer picks Padres vs Marlins, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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MLB | 10/20 | SEA@TOR | UNLOCK THIS PICK | 2 |
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MLB | 10/20 | SEA@TOR | UNLOCK THIS PICK | 0 |
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.
Padres Betting Trends
San Diego has gone 23–27 on the road overall but been strong ATS as underdogs, covering in 9 of their past 11 away games when not favored, showing resilience even in tough territories.
Marlins Betting Trends
Miami has struggled as moneyline favorites at home (-146 or shorter), dropping all four such games, and is just 22–28 at loanDepot Park—reflecting inconsistency in home performance.
Padres vs. Marlins Matchup Trends
Despite the total, eight of the last ten Padres–Marlins matchups have gone over, indicating a strong pattern toward offense regardless of location or line.
San Diego vs. Miami Game Info
What time does San Diego vs Miami start on July 23, 2025?
San Diego vs Miami starts on July 23, 2025 at 12:10 PM EST.
Where is San Diego vs Miami being played?
Venue: loanDepot park.
What are the opening odds for San Diego vs Miami?
Spread: Miami +1.5
Moneyline: San Diego -146, Miami +123
Over/Under: 8
What are the records for San Diego vs Miami?
San Diego: (55-46) | Miami: (47-53)
What is the AI best bet for San Diego vs Miami?
Remi's searched hard and found the best prop for this matchup: O. Lopez over 5 Fantasy Score.. Prices move—always shop for the best number.
What are San Diego vs Miami trending bets?
Despite the total, eight of the last ten Padres–Marlins matchups have gone over, indicating a strong pattern toward offense regardless of location or line.
What are San Diego trending bets?
SD trend: San Diego has gone 23–27 on the road overall but been strong ATS as underdogs, covering in 9 of their past 11 away games when not favored, showing resilience even in tough territories.
What are Miami trending bets?
MIA trend: Miami has struggled as moneyline favorites at home (-146 or shorter), dropping all four such games, and is just 22–28 at loanDepot Park—reflecting inconsistency in home performance.
Where can I find AI Picks for San Diego vs Miami?
See our latest MLB picks and odds pages for 2025 to compare prices before you bet.
San Diego vs. Miami Odds
Remi is pouring through loads of data points on each team. In fact, anytime the San Diego vs Miami trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme travel distance seemingly never follow normal, predictable betting trends.
San Diego vs Miami Opening Odds
SD Moneyline:
-146 MIA Moneyline: +123
SD Spread: -1.5
MIA Spread: +1.5
Over/Under: 8
San Diego vs Miami Live Odds
Games | PTS | ML | SPR | O/U | |
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Oct 24, 2025 8:00PM EDT
Los Angeles Dodgers
Toronto Blue Jays
10/24/25 8PM
Dodgers
Blue Jays
|
–
–
|
-155
+128
|
-1.5 (+112)
+1.5 (-141)
|
O 7.5 (-106)
U 7.5 (-121)
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MLB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers San Diego Padres vs. Miami Marlins on July 23, 2025 at loanDepot park.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
TOR@SEA | OVER 7 | 54.9% | 3 | WIN |
LAD@MIL | UNDER 7.5 | 56.6% | 6 | WIN |
TOR@NYY | OVER 8 | 54.9% | 4 | WIN |
TOR@NYY | CARLOS RODON OVER 1.5 TOTAL WALKS ALLOWED | 53.3% | 3 | WIN |
NYY@TOR | OVER 7.5 | 54.8% | 2 | WIN |
LAD@PHI | OVER 7 | 53.8% | 3 | WIN |
SD@CHC | CHC -109 | 53.8% | 3 | WIN |
SD@CHC | OVER 7.5 | 54.5% | 4 | LOSS |
SD@CHC | CHC -111 | 54.8% | 4 | LOSS |
CIN@LAD | SHOHEI OHTANI OVER 1.5 BASES | 53.5% | 3 | WIN |
BOS@NYY | OVER 7 | 53.8% | 3 | LOSS |
CIN@LAD | ELLY DE LA CRUZ OVER 0.5 BASES | 54.4% | 4 | LOSS |
ARI@SD | SD -131 | 57.3% | 4 | WIN |
DET@BOS | BOS -115 | 56.4% | 5 | WIN |
NYM@CHC | NYM -110 | 54.1% | 3 | WIN |
HOU@ATH | ATH +118 | 50.8% | 4 | WIN |
NYM@CHC | OVER 7 | 54.5% | 3 | WIN |
STL@SF | OVER 7.5 | 55.9% | 5 | LOSS |
KC@LAA | TYLER TOLBERT UNDER 1.5 BASES | 54.4% | 4 | WIN |
MIL@SD | UNDER 9 | 54.7% | 4 | WIN |
MIA@PHI | KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS | 53.3% | 3 | WIN |
WAS@NYM | OVER 8.5 | 56.1% | 6 | LOSS |
LAA@COL | COL +108 | 50.5% | 3 | WIN |
TOR@KC | UNDER 9 | 54.7% | 4 | LOSS |
SEA@KC | KC +1.5 | 62.3% | 5 | LOSS |
NYY@MIN | OVER 9 | 55.1% | 4 | WIN |
MIA@COL | OVER 10.5 | 55.0% | 4 | WIN |
MIA@COL | AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS | 54.3% | 4 | WIN |
SEA@KC | BOBBY WITT UNDER 0.5 SINGLES | 54.4% | 4 | LOSS |
PHI@LAD | LAD -113 | 54.7% | 4 | LOSS |
NYY@BOS | OVER 7.5 | 54.3% | 3 | WIN |
KC@PHI | PHI -130 | 58.3% | 4 | WIN |
LAD@SF | OVER 7.5 | 54.7% | 4 | LOSS |
NYM@PHI | PHI -122 | 55.6% | 4 | WIN |
KC@CLE | KC -104 | 52.0% | 3 | WIN |
CIN@SD | JAKE CRONEWORTH OVER 0.5 HITS | 53.1% | 3 | WIN |
WAS@MIA | MIA -123 | 55.2% | 4 | LOSS |
LAA@KC | UNDER 9.5 | 54.9% | 3 | WIN |
TEX@ARI | UNDER 9 | 54.2% | 4 | WIN |
SF@COL | UNDER 11.5 | 56.4% | 6 | LOSS |
SF@COL | RAFAEL DEVERS OVER 1.5 BASES | 56.1% | 6 | WIN |
MIA@WAS | WAS -110 | 54.4% | 4 | WIN |
NYM@DET | OVER 8.5 | 54.5% | 4 | WIN |
TEX@ARI | UNDER 9.5 | 56.4% | 6 | WIN |
TEX@ARI | ALEJANDRO OSUNA UNDER 1.5 BASES | 54.1% | 4 | LOSS |
ATL@CHC | CHC -116 | 55.1% | 3 | WIN |
PHI@MIL | OVER 8.5 | 55.0% | 3 | WIN |
ARI@LAD | SHOHEI OHTANI OVER 2.5 BASES | 54.2% | 4 | WIN |
SEA@CLE | CLE +1.5 | 57.2% | 3 | WIN |
CHC@SF | CHC -105 | 54.1% | 4 | LOSS |
NYY@CHW | RYAN MCMAHON OVER 0.5 BASES | 54.1% | 4 | WIN |