Orioles vs Guardians Prediction — AI Finds CAN'T MISS MLB Lines & Props (Jul 23)
Updated: 2025-07-21T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The Baltimore Orioles (50–58) head to Progressive Field to face the Cleveland Guardians (59–53) on Wednesday, July 23. Cleveland enters as a -130 favorite on the moneyline, with the total set at 8.5 runs.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Jul 23, 2025
Start Time: 6:40 PM EST
Venue: Progressive Field
Guardians Record: (50-50)
Orioles Record: (44-56)
OPENING ODDS
BAL Moneyline: +109
CLE Moneyline: -129
BAL Spread: +1.5
CLE Spread: -1.5
Over/Under: 8.5
BAL
Betting Trends
- Baltimore has gone 4–6 ATS on the road during their last ten games, struggling to consistently cover when playing away from Camden Yards.
CLE
Betting Trends
- Cleveland is 22–15 as a moneyline favorite this season, performing particularly well at home, and has gone 6–4 ATS when favored in July.
MATCHUP TRENDS
- Eight of Cleveland’s last ten games—with a total set around 8.5—have finished under, suggesting a trend toward low-scoring outings in this matchup.
BAL vs. CLE
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: A. Martinez over 5.5 Fantasy Score.
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Baltimore vs Cleveland Prediction & Odds:
Free MLB Betting Insights for 7/23/25
The Guardians’ bullpen, among the better units in the AL in high-leverage situations, adds another layer of security when holding late-inning leads. Meanwhile, the Orioles will activate veteran starter Zach Eflin off the injured list for this outing, a gamble that could pay off if he manages to shake off rust early. Eflin has posted a 6–5 record with an ERA hovering near 6.00, and his inconsistencies will be tested by a Guardians lineup that is opportunistic and dangerous with runners on. Baltimore’s offense has been inconsistent, relying heavily on youth with Gunnar Henderson and Jackson Holliday, but their lack of execution with runners in scoring position has plagued them throughout July. The O’s bullpen, headlined by closer Félix Bautista, remains a strength, but getting the ball to him with a lead has been rare of late. Baltimore must also overcome a recent trend of failing to cover the spread in road games and their overall inconsistency as an underdog. This matchup will likely come down to who can get the timely hit and whether Eflin can provide length against a Cleveland team that has found its stride at home. Given the trends and the state of both pitching staffs, this contest leans in favor of the Guardians, especially if Bibee can give them six or more effective innings. Expect a game where the margins are tight, but Cleveland’s current rhythm and superior situational hitting offer the edge in what should be a well-contested matchup.
RBI knock 💪 pic.twitter.com/X0g0csPttV
— Baltimore Orioles (@Orioles) July 23, 2025
Baltimore Orioles MLB Preview
The Baltimore Orioles enter Tuesday’s matchup against the Cleveland Guardians searching for a jolt of consistency as they attempt to navigate a season filled with streaky play and missed opportunities. Now sitting at 50–58, the Orioles have lost three of their last four games and continue to show signs of frustration with their inability to string together complete performances. After dropping Monday’s series opener in convincing fashion, Baltimore now turns to veteran right-hander Zach Eflin, who will be activated from the injured list to make his first start since early July. Eflin, who has battled command issues and nagging injuries throughout the year, carries a 6–5 record and ERA just under 6.00 into this outing, and the Orioles are hoping he can stabilize a rotation that’s been unreliable. Baltimore’s recent struggles stem largely from inconsistent offensive production. While young stars like Gunnar Henderson and Jackson Holliday provide flashes of brilliance, the lineup has failed to capitalize with runners in scoring position, leaving far too many opportunities on the table.
Ryan Mountcastle and Colton Cowser have cooled off after strong starts to the summer, and the lack of veteran depth is exposing a team still searching for its identity in tight ballgames. Defensively, Baltimore has remained solid, but the pitching has not backed up the fielding support, as starters frequently struggle to pitch beyond the fifth inning. The bullpen, a rare strength for the club, continues to be led by All-Star closer Félix Bautista and setup man Yennier Cano, but they’ve been underutilized recently due to the lack of leads heading into the late innings. With Eflin’s activation, the Orioles hope to turn the page on their recent pitching woes, but against a surging Guardians lineup that just roughed up their staff for 10 runs, the task is steep. Baltimore has also underperformed in road games, especially when playing as an underdog, failing to cover the run line in a majority of those contests. Tuesday presents a prime opportunity to shift the narrative, but they’ll need a strong, efficient outing from Eflin and better plate discipline across the board. The pressure will be on the bats to generate early support and on Eflin to give them a chance into the middle innings without taxing the bullpen too heavily. If the Orioles are going to steal a win in Cleveland, it will require sharper at-bats, timely hits, and a much-improved approach on the mound—none of which have been consistent hallmarks of their play in recent weeks. Still, if their young stars can rise to the occasion and Eflin delivers a competent outing, Baltimore has enough raw talent to compete. The question is whether they can translate that potential into results before their season drifts too far off course.

Credit: USA TODAY/IMAGN
Cleveland Guardians MLB Preview
The Cleveland Guardians continue to trend in the right direction as they head into Tuesday’s matchup against the struggling Baltimore Orioles, riding a surge of momentum following a convincing 10–5 victory in Monday’s opener. Now 59–53 on the season, Cleveland is firmly entrenched in the American League playoff race and has played some of its most complete baseball at home, where both the bats and the pitching have delivered in clutch moments. Right-hander Tanner Bibee gets the nod for this game, and while his 6–9 record may appear modest, his recent form has been encouraging. In his last outing—ironically also against the Orioles—Bibee went seven strong innings and limited Baltimore to minimal damage, showing improved command and poise. Bibee’s success is reflective of a Guardians rotation that has grown increasingly reliable over the summer months, with the bullpen continuing to lock down close games thanks to arms like Emmanuel Clase and Hunter Gaddis. At the plate, the Guardians have been powered by the relentless consistency of José Ramírez, who remains among the league leaders in home runs and stolen bases, while Josh Naylor and Bo Naylor are also heating up, providing critical left-handed punch in the middle and bottom of the order. Kyle Manzardo, another young contributor, has shown solid plate discipline and has been productive in RBI spots, helping Cleveland create crooked numbers early and apply scoreboard pressure.
As a team, the Guardians have done an excellent job of situational hitting, particularly against right-handed pitchers like Zach Eflin, who returns from the IL for the Orioles after weeks of inactivity. Eflin’s last start against Cleveland was shaky, and the Guardians will look to exploit any early rust with aggressive approaches in the box. Defensively, Cleveland has remained one of the sharper infields in the AL, committing few errors and turning key double plays when needed. Their ability to hold leads late—thanks in large part to their bullpen’s efficiency—has given them confidence in tight games, and that poise has translated to a winning record in one-run contests. Another edge the Guardians bring is their success covering the spread at home, especially when facing sub-.500 teams. With the Orioles currently floundering and sending out a starter working back from injury, the Guardians will aim to strike early and often, forcing Baltimore to play from behind where they’ve been at their weakest. The coaching staff has continued to mix youth with experience effectively, and the team’s chemistry is increasingly evident in their dugout demeanor and on-field execution. As long as Bibee delivers a quality start and the offense remains opportunistic, Cleveland is well-positioned to secure another series win and continue building its postseason resume. This game offers the Guardians a chance to capitalize on home field, deepen their pitching confidence, and maintain their rhythm against an Orioles squad that has not shown the same cohesion or consistency in recent weeks.
Took down the birds for the second night in a row.#GuardsBall | #GuardiWWWins pic.twitter.com/3nu221D1FR
— Cleveland Guardians (@CleGuardians) July 23, 2025
Baltimore vs. Cleveland Prop Picks (AI)
Baltimore vs. Cleveland Prediction (AI)

Remi, our AI sports genius, has been pouring over tons of data from every simulation between the Orioles and Guardians and using recursive machine learning and kick-ass AI to examine the data to a single cover probability.
The Algorithm has been most focused on the growing emphasis human bettors regularly put on coaching factors between a Orioles team going up against a possibly unhealthy Guardians team. We’ve found the true game analytics appear to reflect a moderate lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.
Below is our current AI Baltimore vs Cleveland picks, computer picks Orioles vs Guardians, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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MLB | 10/20 | SEA@TOR | UNLOCK THIS PICK | 2 |
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MLB | 10/20 | SEA@TOR | UNLOCK THIS PICK | 0 |
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.
Orioles Betting Trends
Baltimore has gone 4–6 ATS on the road during their last ten games, struggling to consistently cover when playing away from Camden Yards.
Guardians Betting Trends
Cleveland is 22–15 as a moneyline favorite this season, performing particularly well at home, and has gone 6–4 ATS when favored in July.
Orioles vs. Guardians Matchup Trends
Eight of Cleveland’s last ten games—with a total set around 8.5—have finished under, suggesting a trend toward low-scoring outings in this matchup.
Baltimore vs. Cleveland Game Info
What time does Baltimore vs Cleveland start on July 23, 2025?
Baltimore vs Cleveland starts on July 23, 2025 at 6:40 PM EST.
Where is Baltimore vs Cleveland being played?
Venue: Progressive Field.
What are the opening odds for Baltimore vs Cleveland?
Spread: Cleveland -1.5
Moneyline: Baltimore +109, Cleveland -129
Over/Under: 8.5
What are the records for Baltimore vs Cleveland?
Baltimore: (44-56) | Cleveland: (50-50)
What is the AI best bet for Baltimore vs Cleveland?
Remi's searched hard and found the best prop for this matchup: A. Martinez over 5.5 Fantasy Score.. Prices move—always shop for the best number.
What are Baltimore vs Cleveland trending bets?
Eight of Cleveland’s last ten games—with a total set around 8.5—have finished under, suggesting a trend toward low-scoring outings in this matchup.
What are Baltimore trending bets?
BAL trend: Baltimore has gone 4–6 ATS on the road during their last ten games, struggling to consistently cover when playing away from Camden Yards.
What are Cleveland trending bets?
CLE trend: Cleveland is 22–15 as a moneyline favorite this season, performing particularly well at home, and has gone 6–4 ATS when favored in July.
Where can I find AI Picks for Baltimore vs Cleveland?
See our latest MLB picks and odds pages for 2025 to compare prices before you bet.
Baltimore vs. Cleveland Odds
Remi is pouring through mountains of data on each team. In fact, anytime the Baltimore vs Cleveland trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme temps rarely follow normal, predictable betting trends.
Baltimore vs Cleveland Opening Odds
BAL Moneyline:
+109 CLE Moneyline: -129
BAL Spread: +1.5
CLE Spread: -1.5
Over/Under: 8.5
Baltimore vs Cleveland Live Odds
Games | PTS | ML | SPR | O/U | |
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Oct 24, 2025 9:08PM EDT
Los Angeles Dodgers
Toronto Blue Jays
10/24/25 9:08PM
Dodgers
Blue Jays
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–
–
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-140
+127
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-1.5 (+124)
+1.5 (-140)
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O 7.5 (+107)
U 7.5 (-123)
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MLB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Baltimore Orioles vs. Cleveland Guardians on July 23, 2025 at Progressive Field.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
TOR@SEA | OVER 7 | 54.9% | 3 | WIN |
LAD@MIL | UNDER 7.5 | 56.6% | 6 | WIN |
TOR@NYY | OVER 8 | 54.9% | 4 | WIN |
TOR@NYY | CARLOS RODON OVER 1.5 TOTAL WALKS ALLOWED | 53.3% | 3 | WIN |
NYY@TOR | OVER 7.5 | 54.8% | 2 | WIN |
LAD@PHI | OVER 7 | 53.8% | 3 | WIN |
SD@CHC | CHC -109 | 53.8% | 3 | WIN |
SD@CHC | OVER 7.5 | 54.5% | 4 | LOSS |
SD@CHC | CHC -111 | 54.8% | 4 | LOSS |
CIN@LAD | SHOHEI OHTANI OVER 1.5 BASES | 53.5% | 3 | WIN |
BOS@NYY | OVER 7 | 53.8% | 3 | LOSS |
CIN@LAD | ELLY DE LA CRUZ OVER 0.5 BASES | 54.4% | 4 | LOSS |
ARI@SD | SD -131 | 57.3% | 4 | WIN |
DET@BOS | BOS -115 | 56.4% | 5 | WIN |
NYM@CHC | NYM -110 | 54.1% | 3 | WIN |
HOU@ATH | ATH +118 | 50.8% | 4 | WIN |
NYM@CHC | OVER 7 | 54.5% | 3 | WIN |
STL@SF | OVER 7.5 | 55.9% | 5 | LOSS |
KC@LAA | TYLER TOLBERT UNDER 1.5 BASES | 54.4% | 4 | WIN |
MIL@SD | UNDER 9 | 54.7% | 4 | WIN |
MIA@PHI | KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS | 53.3% | 3 | WIN |
WAS@NYM | OVER 8.5 | 56.1% | 6 | LOSS |
LAA@COL | COL +108 | 50.5% | 3 | WIN |
TOR@KC | UNDER 9 | 54.7% | 4 | LOSS |
SEA@KC | KC +1.5 | 62.3% | 5 | LOSS |
NYY@MIN | OVER 9 | 55.1% | 4 | WIN |
MIA@COL | OVER 10.5 | 55.0% | 4 | WIN |
MIA@COL | AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS | 54.3% | 4 | WIN |
SEA@KC | BOBBY WITT UNDER 0.5 SINGLES | 54.4% | 4 | LOSS |
PHI@LAD | LAD -113 | 54.7% | 4 | LOSS |
NYY@BOS | OVER 7.5 | 54.3% | 3 | WIN |
KC@PHI | PHI -130 | 58.3% | 4 | WIN |
LAD@SF | OVER 7.5 | 54.7% | 4 | LOSS |
NYM@PHI | PHI -122 | 55.6% | 4 | WIN |
KC@CLE | KC -104 | 52.0% | 3 | WIN |
CIN@SD | JAKE CRONEWORTH OVER 0.5 HITS | 53.1% | 3 | WIN |
WAS@MIA | MIA -123 | 55.2% | 4 | LOSS |
LAA@KC | UNDER 9.5 | 54.9% | 3 | WIN |
TEX@ARI | UNDER 9 | 54.2% | 4 | WIN |
SF@COL | UNDER 11.5 | 56.4% | 6 | LOSS |
SF@COL | RAFAEL DEVERS OVER 1.5 BASES | 56.1% | 6 | WIN |
MIA@WAS | WAS -110 | 54.4% | 4 | WIN |
NYM@DET | OVER 8.5 | 54.5% | 4 | WIN |
TEX@ARI | UNDER 9.5 | 56.4% | 6 | WIN |
TEX@ARI | ALEJANDRO OSUNA UNDER 1.5 BASES | 54.1% | 4 | LOSS |
ATL@CHC | CHC -116 | 55.1% | 3 | WIN |
PHI@MIL | OVER 8.5 | 55.0% | 3 | WIN |
ARI@LAD | SHOHEI OHTANI OVER 2.5 BASES | 54.2% | 4 | WIN |
SEA@CLE | CLE +1.5 | 57.2% | 3 | WIN |
CHC@SF | CHC -105 | 54.1% | 4 | LOSS |
NYY@CHW | RYAN MCMAHON OVER 0.5 BASES | 54.1% | 4 | WIN |