Brewers vs. Mariners
Prediction, Odds & Props
Jul 21 | MLB AI Picks

Updated: 2025-07-19T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Milwaukee Brewers (59–40, 2nd NL Central) visit the Seattle Mariners (53–46, 2nd AL West) for a late-season clash in Seattle. The Mariners are slight favorites at –125 moneyline and –1.5 (+172 run line), with the total set at 7 runs, hinting at a tight pitchers’ duel.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Jul 21, 2025

Start Time: 9:40 PM EST​

Venue: T-Mobile Park​

Mariners Record: (53-46)

Brewers Record: (59-40)

OPENING ODDS

MIL Moneyline: +103

SEA Moneyline: -123

MIL Spread: +1.5

SEA Spread: -1.5

Over/Under: 7

MIL
Betting Trends

  • Milwaukee has gone 26–24 ATS as underdogs this season, showing solid value but not consistently outperforming expectations on the roadd.

SEA
Betting Trends

  • Seattle is 5–5 ATS over the last 10 games and 3–2 as ML favorites, with 55.6% wins in those roles.

MATCHUP TRENDS

  • In the Mariners’ last 10 outings with a set total, eight games went over the posted line, suggesting a trend toward offense-heavy, high-scoring affairs despite the modest 7-run total.

MIL vs. SEA
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: J. Polanco over 0.5 Total Bases.

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Milwaukee vs Seattle Prediction & Odds:
Free MLB Betting Insights for 7/21/25

The July 21, 2025 matchup between the Milwaukee Brewers and the Seattle Mariners at T-Mobile Park promises to be a compelling interleague battle featuring two playoff-hopeful squads with contrasting styles and elite starting pitching. With the Mariners entering the contest slightly favored on the moneyline and run line, and the total set at a tight 7 runs, expectations lean toward a well-pitched, low-scoring affair, though both clubs have shown the potential to break out offensively. Milwaukee’s 59–40 record makes them one of the National League’s most consistent performers in 2025, while Seattle at 53–46 is pushing hard to stay in the AL Wild Card hunt. The Brewers will turn to their returning ace Brandon Woodruff, who’s been electric since coming off the injured list, flashing a mid-2.00s ERA and high strikeout totals that reflect his vintage form. Woodruff’s ability to manage contact and work deep into games is essential for a team whose bullpen has occasionally faltered in late innings, despite overall reliability. Milwaukee will lean on Christian Yelich’s consistent veteran presence alongside rising star Jackson Chourio, whose power has added a much-needed spark to a balanced yet streaky offense.

Willy Adames provides crucial right-handed thump and defensive steadiness at short, and his contributions will be particularly key against Seattle’s likely starter, George Kirby, a control-specialist righty who has enjoyed excellent home splits. Kirby’s pinpoint command and low walk rate make him an ideal pitcher for Seattle’s ballpark, which rewards pitchers who limit base runners and induce ground balls. On offense, the Mariners remain dangerous thanks to AL home run leader Cal Raleigh, whose lefty power has been one of the stories of the summer. Seattle has also benefited from timely hitting by J.P. Crawford and Julio Rodríguez, giving their lineup length and pressure throughout the batting order. The Mariners’ recent trend of going over the total in eight of their last ten games, however, suggests a departure from their early-season pitching-first identity and introduces the possibility of fireworks if either starter slips. Both clubs have much at stake—Milwaukee looking to close the gap in the Central Division or solidify a Wild Card berth, and Seattle desperate to stay afloat in the intensely competitive AL playoff race. The key matchups to watch will be Kirby vs. Milwaukee’s left-handed bats and Woodruff’s ability to contain Seattle’s power. Should either bullpen be called upon early, the team that better navigates the middle innings may seize the momentum and the scoreboard. Though the betting odds slightly favor Seattle, Milwaukee’s pedigree and Woodruff’s presence on the mound make this a toss-up by most metrics, likely decided by timely hitting and defensive execution in a game that could have October implications for both sides.

Milwaukee Brewers MLB Preview

The Milwaukee Brewers enter their July 21, 2025 showdown against the Seattle Mariners as one of the National League’s more consistent and disciplined clubs, sitting with a strong 59–40 record and proving themselves as legitimate contenders in the NL Central. Their season has been defined by a return to health and elite form from ace Brandon Woodruff, whose steady dominance atop the rotation has helped balance an offense that, while not overpowering, delivers in critical moments. Christian Yelich remains the team’s most experienced and reliable offensive weapon, with his ability to get on base and disrupt pitchers complemented by breakout rookie Jackson Chourio, whose power and flair in the outfield have electrified Brewers fans throughout the summer. Behind them, the likes of William Contreras and Willy Adames have added depth to the lineup, offering a mix of timely power and solid contact. Milwaukee’s approach at the plate focuses heavily on situational hitting and pitch selection, and that patience has helped them avoid prolonged slumps, even when facing elite arms like George Kirby, who they’re set to oppose in this interleague matchup. One of the Brewers’ biggest advantages has been their defensive discipline, turning routine plays with crisp efficiency while also limiting extra bases with strong positioning and arm strength in the outfield.

On the mound, Woodruff’s resurgence has brought stability, and his high-strikeout, low-walk profile plays well against a Seattle lineup that can swing aggressively and fall into quiet stretches if not careful. The Brewers’ bullpen, though occasionally shaky, has improved thanks to Joel Payamps and Trevor Megill stepping into higher-leverage roles, and Milwaukee will hope not to lean too heavily on them if Woodruff can pitch deep. Strategically, Milwaukee will likely emphasize aggressive baserunning early to test Seattle’s defensive response and challenge Kirby to pitch under pressure with runners on. The Brewers have posted a solid 7–3 ATS record in their last 10 road games and have consistently covered when facing right-handed starters. Their recent form also shows a trend toward lower-scoring outcomes, with the under hitting in eight of their last eleven games, aligning with expectations in a pitcher-friendly setting like T-Mobile Park. Manager Pat Murphy has guided the team with a steady hand, trusting his veterans while also giving opportunities to young standouts, resulting in a roster that feels both hungry and experienced. The Brewers understand the stakes, with the Cubs lurking behind them in the standings and the Wild Card race tightening, and a road win over a quality AL opponent would bolster their confidence heading into a crucial stretch of the schedule. As long as Woodruff sets the tone and the offense capitalizes on the few scoring chances they’ll get, Milwaukee should feel capable of stealing this game despite being the visitors.

The Milwaukee Brewers (59–40, 2nd NL Central) visit the Seattle Mariners (53–46, 2nd AL West) for a late-season clash in Seattle. The Mariners are slight favorites at –125 moneyline and –1.5 (+172 run line), with the total set at 7 runs, hinting at a tight pitchers’ duel. Milwaukee vs Seattle AI Prediction: Free MLB Betting Insights for Jul 21. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Seattle Mariners MLB Preview

The Seattle Mariners return home on July 21, 2025, looking to keep their postseason hopes alive as they prepare to host the Milwaukee Brewers in a high-stakes interleague matchup that could have long-term implications on the AL Wild Card race. With a 53–46 record, Seattle has stayed competitive in a crowded American League thanks in large part to their outstanding pitching staff, anchored by George Kirby, who is expected to take the mound in this contest. Kirby has been brilliant at home, using his elite command, low walk rate, and ability to force weak contact to dominate opposing lineups at T-Mobile Park. His calm demeanor and consistency have made him one of the most dependable arms in the AL, and he’ll need to be sharp against a Milwaukee team that thrives on patient at-bats and situational hitting. Offensively, the Mariners have shown more life in recent weeks, led by the power surge of catcher Cal Raleigh, who continues to lead the American League in home runs and has become a force from the left side of the plate. Julio Rodríguez has also caught fire after a sluggish first half, combining power, speed, and defensive excellence in center field, while J.P. Crawford’s leadership and clutch hitting from the leadoff spot continue to spark the offense.

The Mariners have shown a tendency to thrive in tight, low-scoring games at home, where the spacious park and strong defensive play reduce scoring volatility and put pressure on visiting offenses to capitalize on limited chances. However, a recent trend toward overs—Seattle games have gone over the total in eight of their last ten—signals a shift in dynamics, either from a fatigued bullpen or a more aggressive offensive approach. The bullpen, which had been a strength early in the year, has been tested more heavily in recent weeks, and while Andrés Muñoz still anchors the late innings with electric stuff, the middle relief crew has shown cracks. Offensively, Seattle will aim to apply pressure early on Brandon Woodruff, knowing that allowing him to settle in could result in limited opportunities the deeper he pitches into the game. Manager Scott Servais will likely try to manufacture runs through bunts, steals, and hit-and-run plays to avoid relying solely on home runs in what’s expected to be a tight scoring environment. Seattle is 6–4 ATS in its last 10 home games and tends to cover the run line in close contests where its pitching excels, making them a slight favorite entering the game. The Mariners are well aware of the urgency in every series from here forward, especially as they chase a playoff berth in the increasingly crowded AL landscape. With Kirby on the mound, a supportive home crowd, and an offense trending upward, the Mariners will look to dictate the tempo, control the scoreboard, and protect their turf against a disciplined Brewers squad.

Milwaukee vs. Seattle Prop Picks (AI)

Remi is pouring through tons of datapoints on each line. In fact, anytime the Brewers and Mariners play there’s always several intriguing observations to key in on. Not to mention games played at T-Mobile Park in Jul can often follow normal, predictable patterns.
Remi's searched hard and found the best prop for this matchup: J. Polanco over 0.5 Total Bases.

Milwaukee vs. Seattle Prediction (AI)

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Remi, our AI sports algorithm, has been pouring over mountains of data from every facet between the Brewers and Mariners and using recursive machine learning and kick-ass AI to boil down the data to a single cover probability.

Remi has been most keyed in on the growing factor human bettors regularly put on Milwaukee’s strength factors between a Brewers team going up against a possibly tired Mariners team. Trends look to say the true game analytics appear to reflect a strong lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI Milwaukee vs Seattle picks, computer picks Brewers vs Mariners, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

Brewers Betting Trends

Milwaukee has gone 26–24 ATS as underdogs this season, showing solid value but not consistently outperforming expectations on the roadd.

Mariners Betting Trends

Seattle is 5–5 ATS over the last 10 games and 3–2 as ML favorites, with 55.6% wins in those roles.

Brewers vs. Mariners Matchup Trends

In the Mariners’ last 10 outings with a set total, eight games went over the posted line, suggesting a trend toward offense-heavy, high-scoring affairs despite the modest 7-run total.

Milwaukee vs. Seattle Game Info

Milwaukee vs Seattle starts on July 21, 2025 at 9:40 PM EST.

Spread: Seattle -1.5
Moneyline: Milwaukee +103, Seattle -123
Over/Under: 7

Milwaukee: (59-40)  |  Seattle: (53-46)

Remi's searched hard and found the best prop for this matchup: J. Polanco over 0.5 Total Bases.. Prices move—always shop for the best number.

In the Mariners’ last 10 outings with a set total, eight games went over the posted line, suggesting a trend toward offense-heavy, high-scoring affairs despite the modest 7-run total.

MIL trend: Milwaukee has gone 26–24 ATS as underdogs this season, showing solid value but not consistently outperforming expectations on the roadd.

SEA trend: Seattle is 5–5 ATS over the last 10 games and 3–2 as ML favorites, with 55.6% wins in those roles.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

Milwaukee vs. Seattle Odds

AI algorithm Remi is pouring through mountains of data on each player. In fact, anytime the Milwaukee vs Seattle trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme temps rarely follow normal, predictable patterns.

Milwaukee vs Seattle Opening Odds

MIL Moneyline: +103
SEA Moneyline: -123
MIL Spread: +1.5
SEA Spread: -1.5
Over/Under: 7

Milwaukee vs Seattle Live Odds

Games PTS ML SPR O/U
In Progress
Baltimore Orioles
New York Yankees
In Progress
Orioles
Yankees
+194
-225
+1.5 (+100)
-1.5 (-120)
O 9 (-105)
U 9 (-115)
Sep 27, 2025 2:21PM EDT
St Louis Cardinals
Chicago Cubs
9/27/25 2:21PM
Cardinals
Cubs
 
-170
 
-1.5 (+115)
O 9.5 (-105)
U 9.5 (-115)
Sep 27, 2025 3:09PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/27/25 3:09PM
Rays
Blue Jays
+146
-165
+1.5 (-140)
-1.5 (+120)
O 8.5 (-105)
U 8.5 (-115)
Sep 27, 2025 4:05PM EDT
Chicago White Sox
Washington Nationals
9/27/25 4:05PM
White Sox
Nationals
+103
-113
+1.5 (-200)
-1.5 (+172)
O 8.5 (-115)
U 8.5 (-105)
Sep 27, 2025 4:06PM EDT
Colorado Rockies
San Francisco Giants
9/27/25 4:06PM
Rockies
Giants
+194
-225
+1.5 (-110)
-1.5 (-110)
O 8 (+100)
U 8 (-120)
Sep 27, 2025 4:11PM EDT
New York Mets
Miami Marlins
9/27/25 4:11PM
Mets
Marlins
-128
+117
-1.5 (+130)
+1.5 (-150)
O 8 (-115)
U 8 (-105)
Sep 27, 2025 4:11PM EDT
Detroit Tigers
Boston Red Sox
9/27/25 4:11PM
Tigers
Red Sox
+111
-122
+1.5 (-190)
-1.5 (+164)
O 9 (+100)
U 9 (-120)
Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
+178
-205
+1.5 (-120)
-1.5 (+100)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
+119
-131
+1.5 (-185)
-1.5 (+160)
O 7.5 (-120)
U 7.5 (+100)
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
+149
-168
+1.5 (-145)
-1.5 (+125)
O 8 (-105)
U 8 (-115)
Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
+125
-138
+1.5 (-185)
-1.5 (+160)
O 7 (-120)
U 7 (+100)
Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
+121
-133
+1.5 (-180)
-1.5 (+156)
O 7.5 (-115)
U 7.5 (-105)
Sep 27, 2025 9:39PM EDT
Houston Astros
Los Angeles Angels
9/27/25 9:39PM
Astros
Angels
-138
+125
-1.5 (+115)
+1.5 (-135)
O 9 (-110)
U 9 (-110)
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
+105
-115
+1.5 (-200)
-1.5 (+172)
O 7 (-120)
U 7 (+100)
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
+105
-115
+1.5 (-190)
-1.5 (+164)
O 10 (-115)
U 10 (-105)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Milwaukee Brewers vs. Seattle Mariners on July 21, 2025 at T-Mobile Park.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
ARI@SD SD -131 57.3% 4 WIN
DET@BOS BOS -115 56.4% 5 WIN
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS