White Sox vs. Pirates
Prediction, Odds & Props
Jul 18 | MLB AI Picks

Updated: 2025-07-16T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Chicago White Sox hit the road to take on the Pittsburgh Pirates at PNC Park in the first game of a three‑game interleague set. With young arms on both sides and playoff hopes fleeting for both clubs, this showdown could come down to bullpen depth and execution in tight situations.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Jul 18, 2025

Start Time: 6:40 PM EST​

Venue: PNC Park​

Pirates Record: (39-58)

White Sox Record: (32-65)

OPENING ODDS

CHW Moneyline: +136

PIT Moneyline: -162

CHW Spread: +1.5

PIT Spread: -1.5

Over/Under: 8.5

CHW
Betting Trends

  • Chicago is 3‑7 ATS in its last 10 games, struggling to cover even as underdogs during recent outings.

PIT
Betting Trends

  • Pittsburgh has been 5‑2 ATS in its last 7 home games, showing improved value at PNC Park lately.

MATCHUP TRENDS

  • In matchups where the total is in the 8–9 range and the visiting team is a slight underdog, the under team has covered 65% of the time—something to watch in what might be a pitchers’ duel.

CHW vs. PIT
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: E. Quero under 1.5 Hits+Runs+RBI.

LIVE MLB ODDS

MLB ODDS COMPARISON

WANT MORE AI PICKS?

VAULT
VS. SPREAD
308-221
VAULT
NET UNITS
(INCL VIG)
+418
VAULT
NET PROFIT
(INCL VIG)
$100/UNIT
$41,803
EXECUTIVE
VS. SPREAD
1551-1329
EXECUTIVE
NET UNITS
(INCL VIG)
+365.7
EXECUTIVE
NET PROFIT
(INCL VIG)
$100/UNIT
$36,569

AI SPORTS PICK PRODUCTS

Create a Free Account

‘Create an Account’ to Get Remi’s Picks Today.

Remi Finds New Picks

Remi calculates the probability a team will cover the line.

Remi Works 24/7

Remi uses this probability to assign units to each pick.

Get Remi's AI Picks

Get Remi’s Top AI Sports Picks sent direct to your inbox.

Chicago White Sox vs Pittsburgh Prediction & Odds:
Free MLB Betting Insights for 7/18/25

Friday night’s interleague matchup at PNC Park between the struggling Chicago White Sox and the steadily improving Pittsburgh Pirates represents a crossroads for two franchises with diverging short-term outlooks but similar long-term ambitions. The White Sox arrive at 32–65, mired in one of the worst records in the majors and battling internal instability and roster turnover as they lean heavily into youth development. The Pirates, at 45–52, are far from elite but have played solid baseball recently, especially at home, and are finding their identity through a mix of young talent and savvy veterans. The spotlight in this opener falls on two intriguing starters—rookie right-hander Jonathan Cannon for Chicago and veteran lefty Bailey Falter for Pittsburgh. Cannon, making just his second big-league start, enters with a promising 2.08 ERA in limited action, known for his command, sinker-induced grounders, and poise well beyond his years. Falter, though prone to occasional blowups, has pitched effectively at home and enters with a 7–6 record and a 4.44 ERA, giving the Pirates a shot at stability and innings. The White Sox offense remains an issue, ranking bottom-five in MLB in most offensive categories including slugging and OBP. Still, signs of life have come from prospects like Edgar Quero and Chase Meidroth, who are getting reps and showing flashes at the plate. For Pittsburgh, their offense is far more competent at home, batting .265 as a team with timely production from Nick Gonzales, Ke’Bryan Hayes, and Jack Suwinski.

While neither team boasts a true MVP-caliber bat, Pittsburgh’s consistent situational hitting and OBP advantage make them more capable of piecing together runs. Defensively, the Pirates also hold an edge, ranking top-10 in defensive efficiency, while the White Sox continue to be plagued by errors and misplays in critical spots. The bullpen comparison leans toward the home team as well—Pittsburgh relievers have maintained a respectable 3.77 ERA at home and have closed out tight games with more consistency, while the White Sox bullpen owns a 4.50 ERA and has often unraveled late, costing them several winnable contests. From a betting and trends perspective, Chicago is just 3–7 ATS in their last 10 and a dismal 11–36 on the road. Pittsburgh, meanwhile, is 5–2 ATS over their last seven home games and appears to be gaining confidence as a home favorite. The game total is hovering around 8, and based on both starting pitchers’ profiles and inconsistent offenses, there’s a decent case for the under hitting—especially if Cannon continues to pitch to contact and Falter avoids early damage. That said, if either bullpen is forced into action too early, the score could tip over quickly. Ultimately, this game shapes up as a test of developmental patience versus emerging structure: the White Sox aim to get reps and evaluate youth, while the Pirates want to build momentum and execute cleaner, tighter baseball. For Chicago to have a shot, Cannon must limit baserunners and their offense needs to cash in on rare RISP chances. For Pittsburgh, a typical workmanlike outing from Falter, along with a solid bullpen showing, should be enough to claim the opener and extend their recent home success.

Chicago White Sox White Sox MLB Preview

The Chicago White Sox enter Friday’s contest against the Pittsburgh Pirates at PNC Park facing the harsh reality of a 32–65 record, the worst in the American League and a reflection of a franchise fully entrenched in a rebuild. Despite the discouraging win-loss mark, the team has quietly shifted its focus from competitiveness to development, allowing a host of young players to get valuable major-league experience as the front office evaluates the roster’s long-term potential. Manager Pedro Grifol has leaned into this transitional phase by giving starts and key opportunities to a mix of prospects and low-cost veterans, hoping to identify cornerstones for the next competitive White Sox team. Among those grabbing attention is Friday’s starting pitcher Jonathan Cannon, a rookie right-hander with a 2.08 ERA in limited innings and a ground-ball-heavy profile that fits well against lineups like Pittsburgh’s, which tend to rely on contact rather than raw power. Cannon, known for his poise and pitch efficiency, will aim to give the White Sox five to six quality innings and keep the game manageable for a bullpen that has struggled in high-leverage spots. The relief corps owns a 4.50 ERA and has repeatedly collapsed late in games, undermining otherwise solid starting efforts. Cannon’s ability to work ahead in counts and generate early outs will be crucial, especially with a Pirates team that’s been hitting .265 at home and showing better on-base discipline in recent weeks.

Offensively, the White Sox are near the bottom of the league in most categories—slugging, OPS, and runs per game—but some emerging bats have shown flashes. Edgar Quero, a highly touted catching prospect, has provided both defensive stability and surprising pop, while Chase Meidroth and Lenyn Sosa are getting extended looks at second and third base. However, run production remains inconsistent and situational hitting has been a major weakness, with Chicago batting below .220 with runners in scoring position. This offensive ineptitude has forced the team into a narrow margin for error almost every night, putting pressure on their young arms to pitch nearly flawless baseball. The White Sox have been particularly bad on the road, going just 11–36 away from Guaranteed Rate Field, and 3–7 against the spread in their last 10 games—underscoring their struggle to remain competitive for full nine-inning stretches. In betting terms, they enter Friday as clear underdogs, and the total is projected around eight runs, which reflects modest expectations for both lineups. However, in games where the underdog features a rookie starter and a modest total, the spread has historically tilted toward the dog covering about 60–65% of the time. For Chicago to pull off an upset or even cover the run line, Cannon will need to be sharp early, the defense must avoid costly errors, and the lineup must take advantage of any free passes or defensive miscues offered by Pirates starter Bailey Falter. It’s not an impossible formula, but for a club playing out the string in 2025, it’s yet another opportunity to measure growth in an otherwise forgettable season, and to prove that their youth movement might be gaining traction despite the harsh standings.

The Chicago White Sox hit the road to take on the Pittsburgh Pirates at PNC Park in the first game of a three‑game interleague set. With young arms on both sides and playoff hopes fleeting for both clubs, this showdown could come down to bullpen depth and execution in tight situations. Chicago White Sox vs Pittsburgh AI Prediction: Free MLB Betting Insights for Jul 18. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Pittsburgh Pirates MLB Preview

The Pittsburgh Pirates return home to PNC Park on Friday, July 18, to host the struggling Chicago White Sox in the opener of a three-game interleague series, bringing with them a renewed sense of confidence after a promising stretch of performances in front of their home crowd. Sitting at 45–52, the Pirates remain outside the immediate playoff picture, but a recent upswing in form—particularly at home, where they’ve gone 5–2 ATS in their last seven games—has helped stabilize what had been an inconsistent first half. Manager Derek Shelton continues to maximize the value of a balanced roster that mixes veteran steadiness with youthful upside, and that blend has translated into more composed, fundamentally sound baseball. Leading the charge on the mound Friday will be Bailey Falter, a left-hander with a 7–6 record and a 4.44 ERA across 19 starts, who has provided the rotation with dependable innings and flashed strong command of his fastball-changeup combo. Falter has allowed three earned runs or fewer in six of his last eight outings and has generally excelled at keeping the ball in the yard—an essential trait when pitching at the hitter-neutral confines of PNC Park. The Pirates’ offense, though not overwhelming, has quietly become one of the more efficient contact-based lineups in the league when playing at home, batting .265 with a .340 on-base percentage in their last 15 games at PNC. Jack Suwinski and Ke’Bryan Hayes continue to anchor the middle of the order, while rookie second baseman Nick Gonzales has emerged as a consistent producer in high-leverage situations, giving Pittsburgh multiple ways to manufacture runs even without relying heavily on the long ball.

The Pirates’ defense has also contributed to their improvement, with one of the best team fielding percentages in the National League and multiple above-average infield gloves helping convert outs and limit rallies. Perhaps their most notable advantage on Friday lies in bullpen reliability—closer David Bednar has converted 21 of 24 save opportunities, while setup men Carmen Mlodzinski and Aroldis Chapman have held opposing hitters to a collective .197 batting average since June 1. In tight games, this unit has demonstrated the ability to shut things down quickly and protect narrow leads, something the White Sox have lacked all season. With Chicago sending rookie Jonathan Cannon to the mound, the Pirates will likely adopt an aggressive offensive strategy early, looking to test the young righty’s command and composure through a mix of small-ball tactics and patient, extended at-bats. Pittsburgh’s betting edge is also worth noting—they are 33–15 ATS this season when favored by 1.5 runs or less and have cashed overs and unders consistently based on matchup-specific dynamics. With the over/under set near 8 runs and two lineups that don’t profile as power-heavy, this game leans toward a low-scoring affair, provided Falter executes and Cannon avoids early implosion. For Pittsburgh, a win on Friday not only strengthens their home dominance but also provides an opportunity to chip away at the standings in a wide-open NL Wild Card race. If they follow their blueprint—solid starting pitching, clean defense, timely hitting, and a shutdown bullpen—they have all the tools needed to handle a rebuilding Chicago team and continue building momentum in front of their fans.

Chicago White Sox vs. Pittsburgh Prop Picks (AI)

Remi is pouring through tons of data on each team. In fact, anytime the White Sox and Pirates play there’s always several intriguing angles to key in on. Not to mention games played at PNC Park in Jul almost always follow normal, predictable patterns.
Remi's searched hard and found the best prop for this matchup: E. Quero under 1.5 Hits+Runs+RBI.

Chicago White Sox vs. Pittsburgh Prediction (AI)

Remi Robot Icon

Remi, our AI sports wizard, has been pouring over mountains of data from every facet between the White Sox and Pirates and using recursive machine learning and industry leading AI to boil down the data to a single cover probability.

Remi has been most keyed in on the trending weight human bettors often put on Pittsburgh’s strength factors between a White Sox team going up against a possibly improved Pirates team. It appears the true game analytics might reflect a slight lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI Chicago White Sox vs Pittsburgh picks, computer picks White Sox vs Pirates, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
MLB 9/26 DET@BOS UNLOCK THIS PICK 5 EXECUTIVE Locked EXECUTIVE
MLB 9/26 BAL@NYY UNLOCK THIS PICK 4 INTEL Locked INTEL
MLB 9/26 ARI@SD UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
MLB 9/26 NYM@MIA UNLOCK THIS PICK 1 INTEL Locked INTEL
MLB 9/26 NYM@MIA GET FREE PICK NOW 1
MLB 9/26 COL@SF UNLOCK THIS PICK 0 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

White Sox Betting Trends

Chicago is 3‑7 ATS in its last 10 games, struggling to cover even as underdogs during recent outings.

Pirates Betting Trends

Pittsburgh has been 5‑2 ATS in its last 7 home games, showing improved value at PNC Park lately.

White Sox vs. Pirates Matchup Trends

In matchups where the total is in the 8–9 range and the visiting team is a slight underdog, the under team has covered 65% of the time—something to watch in what might be a pitchers’ duel.

Chicago White Sox vs. Pittsburgh Game Info

Chicago White Sox vs Pittsburgh starts on July 18, 2025 at 6:40 PM EST.

Spread: Pittsburgh -1.5
Moneyline: Chicago White Sox +136, Pittsburgh -162
Over/Under: 8.5

Chicago White Sox: (32-65)  |  Pittsburgh: (39-58)

Remi's searched hard and found the best prop for this matchup: E. Quero under 1.5 Hits+Runs+RBI.. Prices move—always shop for the best number.

In matchups where the total is in the 8–9 range and the visiting team is a slight underdog, the under team has covered 65% of the time—something to watch in what might be a pitchers’ duel.

CHW trend: Chicago is 3‑7 ATS in its last 10 games, struggling to cover even as underdogs during recent outings.

PIT trend: Pittsburgh has been 5‑2 ATS in its last 7 home games, showing improved value at PNC Park lately.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

Chicago White Sox vs. Pittsburgh Odds

AI algorithm Remi is pouring through tons of data on each team. In fact, anytime the Chicago White Sox vs Pittsburgh trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme altitude rarely follow normal, predictable betting trends.

Chicago White Sox vs Pittsburgh Opening Odds

CHW Moneyline: +136
PIT Moneyline: -162
CHW Spread: +1.5
PIT Spread: -1.5
Over/Under: 8.5

Chicago White Sox vs Pittsburgh Live Odds

Games PTS ML SPR O/U
Sep 27, 2025 1:06PM EDT
Baltimore Orioles
New York Yankees
9/27/25 1:06PM
Orioles
Yankees
+194
-235
+1.5 (-105)
-1.5 (-114)
O 8.5 (-122)
U 8.5 (+100)
Sep 27, 2025 2:21PM EDT
St Louis Cardinals
Chicago Cubs
9/27/25 2:21PM
Cardinals
Cubs
 
-168
 
-1.5 (+118)
O 9 (-122)
U 9 (+100)
Sep 27, 2025 3:09PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/27/25 3:09PM
Rays
Blue Jays
+132
-156
+1.5 (-154)
-1.5 (+128)
O 8.5 (-106)
U 8.5 (-114)
Sep 27, 2025 4:06PM EDT
Chicago White Sox
Washington Nationals
9/27/25 4:06PM
White Sox
Nationals
+102
-120
-1.5 (+162)
+1.5 (-196)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 4:06PM EDT
Colorado Rockies
San Francisco Giants
9/27/25 4:06PM
Rockies
Giants
+198
-240
+1.5 (-110)
-1.5 (-110)
O 8 (-108)
U 8 (-112)
Sep 27, 2025 4:11PM EDT
New York Mets
Miami Marlins
9/27/25 4:11PM
Mets
Marlins
-124
+106
-1.5 (+130)
+1.5 (-156)
O 8.5 (-112)
U 8.5 (-108)
Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
+177
-197
+1.5 (-118)
-1.5 (-102)
O 8.5 (-118)
U 8.5 (-102)
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
+128
-152
+1.5 (-178)
-1.5 (+146)
O 7.5 (-120)
U 7.5 (-102)
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
+143
-158
+1.5 (-150)
-1.5 (+130)
O 8.5 (+100)
U 8.5 (-120)
Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
+132
-156
+1.5 (-172)
-1.5 (+142)
O 7 (-120)
U 7 (-102)
Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
+120
-132
+1.5 (-180)
-1.5 (+157)
O 7.5 (-115)
U 7.5 (-105)
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
+102
-120
+1.5 (-215)
-1.5 (+180)
O 7.5 (-110)
U 7.5 (-110)
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
+104
-115
+1.5 (-185)
-1.5 (+161)
O 10 (-110)
U 10 (-110)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Chicago White Sox White Sox vs. Pittsburgh Pirates on July 18, 2025 at PNC Park.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS
CIN@ARI KEBRYAN HAYES STRIKEOUTS UNDER 0.5 56.2% 6 WIN
LAD@SD SD +110 50.9% 6 WIN