White Sox vs. Pirates
Prediction, Odds & Props
Jul 18 | MLB AI Picks
Updated: 2025-07-16T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The Chicago White Sox hit the road to take on the Pittsburgh Pirates at PNC Park in the first game of a three‑game interleague set. With young arms on both sides and playoff hopes fleeting for both clubs, this showdown could come down to bullpen depth and execution in tight situations.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Jul 18, 2025
Start Time: 6:40 PM EST
Venue: PNC Park
Pirates Record: (39-58)
White Sox Record: (32-65)
OPENING ODDS
CHW Moneyline: +136
PIT Moneyline: -162
CHW Spread: +1.5
PIT Spread: -1.5
Over/Under: 8.5
CHW
Betting Trends
- Chicago is 3‑7 ATS in its last 10 games, struggling to cover even as underdogs during recent outings.
PIT
Betting Trends
- Pittsburgh has been 5‑2 ATS in its last 7 home games, showing improved value at PNC Park lately.
MATCHUP TRENDS
- In matchups where the total is in the 8–9 range and the visiting team is a slight underdog, the under team has covered 65% of the time—something to watch in what might be a pitchers’ duel.
CHW vs. PIT
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: E. Quero under 1.5 Hits+Runs+RBI.
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Chicago White Sox vs Pittsburgh Prediction & Odds:
Free MLB Betting Insights for 7/18/25
While neither team boasts a true MVP-caliber bat, Pittsburgh’s consistent situational hitting and OBP advantage make them more capable of piecing together runs. Defensively, the Pirates also hold an edge, ranking top-10 in defensive efficiency, while the White Sox continue to be plagued by errors and misplays in critical spots. The bullpen comparison leans toward the home team as well—Pittsburgh relievers have maintained a respectable 3.77 ERA at home and have closed out tight games with more consistency, while the White Sox bullpen owns a 4.50 ERA and has often unraveled late, costing them several winnable contests. From a betting and trends perspective, Chicago is just 3–7 ATS in their last 10 and a dismal 11–36 on the road. Pittsburgh, meanwhile, is 5–2 ATS over their last seven home games and appears to be gaining confidence as a home favorite. The game total is hovering around 8, and based on both starting pitchers’ profiles and inconsistent offenses, there’s a decent case for the under hitting—especially if Cannon continues to pitch to contact and Falter avoids early damage. That said, if either bullpen is forced into action too early, the score could tip over quickly. Ultimately, this game shapes up as a test of developmental patience versus emerging structure: the White Sox aim to get reps and evaluate youth, while the Pirates want to build momentum and execute cleaner, tighter baseball. For Chicago to have a shot, Cannon must limit baserunners and their offense needs to cash in on rare RISP chances. For Pittsburgh, a typical workmanlike outing from Falter, along with a solid bullpen showing, should be enough to claim the opener and extend their recent home success.
Mark Buehrle is iconic for this one 🤣
— Chicago White Sox (@whitesox) July 17, 2025
The final episode of '05 Forever, presented by @Rate_Mortgages, is out now.
Chicago White Sox White Sox MLB Preview
The Chicago White Sox enter Friday’s contest against the Pittsburgh Pirates at PNC Park facing the harsh reality of a 32–65 record, the worst in the American League and a reflection of a franchise fully entrenched in a rebuild. Despite the discouraging win-loss mark, the team has quietly shifted its focus from competitiveness to development, allowing a host of young players to get valuable major-league experience as the front office evaluates the roster’s long-term potential. Manager Pedro Grifol has leaned into this transitional phase by giving starts and key opportunities to a mix of prospects and low-cost veterans, hoping to identify cornerstones for the next competitive White Sox team. Among those grabbing attention is Friday’s starting pitcher Jonathan Cannon, a rookie right-hander with a 2.08 ERA in limited innings and a ground-ball-heavy profile that fits well against lineups like Pittsburgh’s, which tend to rely on contact rather than raw power. Cannon, known for his poise and pitch efficiency, will aim to give the White Sox five to six quality innings and keep the game manageable for a bullpen that has struggled in high-leverage spots. The relief corps owns a 4.50 ERA and has repeatedly collapsed late in games, undermining otherwise solid starting efforts. Cannon’s ability to work ahead in counts and generate early outs will be crucial, especially with a Pirates team that’s been hitting .265 at home and showing better on-base discipline in recent weeks.
Offensively, the White Sox are near the bottom of the league in most categories—slugging, OPS, and runs per game—but some emerging bats have shown flashes. Edgar Quero, a highly touted catching prospect, has provided both defensive stability and surprising pop, while Chase Meidroth and Lenyn Sosa are getting extended looks at second and third base. However, run production remains inconsistent and situational hitting has been a major weakness, with Chicago batting below .220 with runners in scoring position. This offensive ineptitude has forced the team into a narrow margin for error almost every night, putting pressure on their young arms to pitch nearly flawless baseball. The White Sox have been particularly bad on the road, going just 11–36 away from Guaranteed Rate Field, and 3–7 against the spread in their last 10 games—underscoring their struggle to remain competitive for full nine-inning stretches. In betting terms, they enter Friday as clear underdogs, and the total is projected around eight runs, which reflects modest expectations for both lineups. However, in games where the underdog features a rookie starter and a modest total, the spread has historically tilted toward the dog covering about 60–65% of the time. For Chicago to pull off an upset or even cover the run line, Cannon will need to be sharp early, the defense must avoid costly errors, and the lineup must take advantage of any free passes or defensive miscues offered by Pirates starter Bailey Falter. It’s not an impossible formula, but for a club playing out the string in 2025, it’s yet another opportunity to measure growth in an otherwise forgettable season, and to prove that their youth movement might be gaining traction despite the harsh standings.

Credit: USA TODAY/IMAGN
Pittsburgh Pirates MLB Preview
The Pittsburgh Pirates return home to PNC Park on Friday, July 18, to host the struggling Chicago White Sox in the opener of a three-game interleague series, bringing with them a renewed sense of confidence after a promising stretch of performances in front of their home crowd. Sitting at 45–52, the Pirates remain outside the immediate playoff picture, but a recent upswing in form—particularly at home, where they’ve gone 5–2 ATS in their last seven games—has helped stabilize what had been an inconsistent first half. Manager Derek Shelton continues to maximize the value of a balanced roster that mixes veteran steadiness with youthful upside, and that blend has translated into more composed, fundamentally sound baseball. Leading the charge on the mound Friday will be Bailey Falter, a left-hander with a 7–6 record and a 4.44 ERA across 19 starts, who has provided the rotation with dependable innings and flashed strong command of his fastball-changeup combo. Falter has allowed three earned runs or fewer in six of his last eight outings and has generally excelled at keeping the ball in the yard—an essential trait when pitching at the hitter-neutral confines of PNC Park. The Pirates’ offense, though not overwhelming, has quietly become one of the more efficient contact-based lineups in the league when playing at home, batting .265 with a .340 on-base percentage in their last 15 games at PNC. Jack Suwinski and Ke’Bryan Hayes continue to anchor the middle of the order, while rookie second baseman Nick Gonzales has emerged as a consistent producer in high-leverage situations, giving Pittsburgh multiple ways to manufacture runs even without relying heavily on the long ball.
The Pirates’ defense has also contributed to their improvement, with one of the best team fielding percentages in the National League and multiple above-average infield gloves helping convert outs and limit rallies. Perhaps their most notable advantage on Friday lies in bullpen reliability—closer David Bednar has converted 21 of 24 save opportunities, while setup men Carmen Mlodzinski and Aroldis Chapman have held opposing hitters to a collective .197 batting average since June 1. In tight games, this unit has demonstrated the ability to shut things down quickly and protect narrow leads, something the White Sox have lacked all season. With Chicago sending rookie Jonathan Cannon to the mound, the Pirates will likely adopt an aggressive offensive strategy early, looking to test the young righty’s command and composure through a mix of small-ball tactics and patient, extended at-bats. Pittsburgh’s betting edge is also worth noting—they are 33–15 ATS this season when favored by 1.5 runs or less and have cashed overs and unders consistently based on matchup-specific dynamics. With the over/under set near 8 runs and two lineups that don’t profile as power-heavy, this game leans toward a low-scoring affair, provided Falter executes and Cannon avoids early implosion. For Pittsburgh, a win on Friday not only strengthens their home dominance but also provides an opportunity to chip away at the standings in a wide-open NL Wild Card race. If they follow their blueprint—solid starting pitching, clean defense, timely hitting, and a shutdown bullpen—they have all the tools needed to handle a rebuilding Chicago team and continue building momentum in front of their fans.
Our projected starters for Yinzerpalooza Weekend 💛 pic.twitter.com/0zSfYoyC9r
— Pittsburgh Pirates (@Pirates) July 17, 2025
Chicago White Sox vs. Pittsburgh Prop Picks (AI)
Chicago White Sox vs. Pittsburgh Prediction (AI)

Remi, our AI sports wizard, has been pouring over mountains of data from every facet between the White Sox and Pirates and using recursive machine learning and industry leading AI to boil down the data to a single cover probability.
Remi has been most keyed in on the trending weight human bettors often put on Pittsburgh’s strength factors between a White Sox team going up against a possibly improved Pirates team. It appears the true game analytics might reflect a slight lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.
Below is our current AI Chicago White Sox vs Pittsburgh picks, computer picks White Sox vs Pirates, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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MLB | 9/26 | DET@BOS | UNLOCK THIS PICK | 5 |
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MLB | 9/26 | BAL@NYY | UNLOCK THIS PICK | 4 |
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MLB | 9/26 | ARI@SD | UNLOCK THIS PICK | 4 |
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MLB | 9/26 | NYM@MIA | UNLOCK THIS PICK | 1 |
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MLB | 9/26 | NYM@MIA | GET FREE PICK NOW | 1 | – | |
MLB | 9/26 | COL@SF | UNLOCK THIS PICK | 0 |
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.
White Sox Betting Trends
Chicago is 3‑7 ATS in its last 10 games, struggling to cover even as underdogs during recent outings.
Pirates Betting Trends
Pittsburgh has been 5‑2 ATS in its last 7 home games, showing improved value at PNC Park lately.
White Sox vs. Pirates Matchup Trends
In matchups where the total is in the 8–9 range and the visiting team is a slight underdog, the under team has covered 65% of the time—something to watch in what might be a pitchers’ duel.
Chicago White Sox vs. Pittsburgh Game Info
What time does Chicago White Sox vs Pittsburgh start on July 18, 2025?
Chicago White Sox vs Pittsburgh starts on July 18, 2025 at 6:40 PM EST.
Where is Chicago White Sox vs Pittsburgh being played?
Venue: PNC Park.
What are the opening odds for Chicago White Sox vs Pittsburgh?
Spread: Pittsburgh -1.5
Moneyline: Chicago White Sox +136, Pittsburgh -162
Over/Under: 8.5
What are the records for Chicago White Sox vs Pittsburgh?
Chicago White Sox: (32-65) | Pittsburgh: (39-58)
What is the AI best bet for Chicago White Sox vs Pittsburgh?
Remi's searched hard and found the best prop for this matchup: E. Quero under 1.5 Hits+Runs+RBI.. Prices move—always shop for the best number.
What are Chicago White Sox vs Pittsburgh trending bets?
In matchups where the total is in the 8–9 range and the visiting team is a slight underdog, the under team has covered 65% of the time—something to watch in what might be a pitchers’ duel.
What are Chicago White Sox trending bets?
CHW trend: Chicago is 3‑7 ATS in its last 10 games, struggling to cover even as underdogs during recent outings.
What are Pittsburgh trending bets?
PIT trend: Pittsburgh has been 5‑2 ATS in its last 7 home games, showing improved value at PNC Park lately.
Where can I find AI Picks for Chicago White Sox vs Pittsburgh?
See our latest MLB picks and odds pages for 2025 to compare prices before you bet.
Chicago White Sox vs. Pittsburgh Odds
AI algorithm Remi is pouring through tons of data on each team. In fact, anytime the Chicago White Sox vs Pittsburgh trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme altitude rarely follow normal, predictable betting trends.
Chicago White Sox vs Pittsburgh Opening Odds
CHW Moneyline:
+136 PIT Moneyline: -162
CHW Spread: +1.5
PIT Spread: -1.5
Over/Under: 8.5
Chicago White Sox vs Pittsburgh Live Odds
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O 8.5 (-122)
U 8.5 (+100)
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U 9 (+100)
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U 8.5 (-114)
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O 8.5 (-110)
U 8.5 (-110)
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+198
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+1.5 (-110)
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O 8 (-108)
U 8 (-112)
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-124
+106
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-1.5 (+130)
+1.5 (-156)
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O 8.5 (-112)
U 8.5 (-108)
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Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
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–
–
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+177
-197
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+1.5 (-118)
-1.5 (-102)
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O 8.5 (-118)
U 8.5 (-102)
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Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
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–
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+128
-152
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+1.5 (-178)
-1.5 (+146)
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O 7.5 (-120)
U 7.5 (-102)
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Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
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–
–
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+143
-158
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+1.5 (-150)
-1.5 (+130)
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O 8.5 (+100)
U 8.5 (-120)
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Sep 27, 2025 7:16PM EDT
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+132
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O 7 (-120)
U 7 (-102)
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Sep 27, 2025 8:40PM EDT
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9/27/25 8:40PM
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+120
-132
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+1.5 (-180)
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O 7.5 (-115)
U 7.5 (-105)
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Sep 27, 2025 9:41PM EDT
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9/27/25 9:41PM
Dodgers
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+102
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+1.5 (-215)
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O 7.5 (-110)
U 7.5 (-110)
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Sep 27, 2025 10:05PM EDT
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–
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+104
-115
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+1.5 (-185)
-1.5 (+161)
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O 10 (-110)
U 10 (-110)
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MLB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Chicago White Sox White Sox vs. Pittsburgh Pirates on July 18, 2025 at PNC Park.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
NYM@CHC | NYM -110 | 54.1% | 3 | WIN |
HOU@ATH | ATH +118 | 50.8% | 4 | WIN |
NYM@CHC | OVER 7 | 54.5% | 3 | WIN |
STL@SF | OVER 7.5 | 55.9% | 5 | LOSS |
KC@LAA | TYLER TOLBERT UNDER 1.5 BASES | 54.4% | 4 | WIN |
MIL@SD | UNDER 9 | 54.7% | 4 | WIN |
MIA@PHI | KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS | 53.3% | 3 | WIN |
WAS@NYM | OVER 8.5 | 56.1% | 6 | LOSS |
LAA@COL | COL +108 | 50.5% | 3 | WIN |
TOR@KC | UNDER 9 | 54.7% | 4 | LOSS |
SEA@KC | KC +1.5 | 62.3% | 5 | LOSS |
NYY@MIN | OVER 9 | 55.1% | 4 | WIN |
MIA@COL | OVER 10.5 | 55.0% | 4 | WIN |
MIA@COL | AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS | 54.3% | 4 | WIN |
SEA@KC | BOBBY WITT UNDER 0.5 SINGLES | 54.4% | 4 | LOSS |
PHI@LAD | LAD -113 | 54.7% | 4 | LOSS |
NYY@BOS | OVER 7.5 | 54.3% | 3 | WIN |
KC@PHI | PHI -130 | 58.3% | 4 | WIN |
LAD@SF | OVER 7.5 | 54.7% | 4 | LOSS |
NYM@PHI | PHI -122 | 55.6% | 4 | WIN |
KC@CLE | KC -104 | 52.0% | 3 | WIN |
CIN@SD | JAKE CRONEWORTH OVER 0.5 HITS | 53.1% | 3 | WIN |
WAS@MIA | MIA -123 | 55.2% | 4 | LOSS |
LAA@KC | UNDER 9.5 | 54.9% | 3 | WIN |
TEX@ARI | UNDER 9 | 54.2% | 4 | WIN |
SF@COL | UNDER 11.5 | 56.4% | 6 | LOSS |
SF@COL | RAFAEL DEVERS OVER 1.5 BASES | 56.1% | 6 | WIN |
MIA@WAS | WAS -110 | 54.4% | 4 | WIN |
NYM@DET | OVER 8.5 | 54.5% | 4 | WIN |
TEX@ARI | UNDER 9.5 | 56.4% | 6 | WIN |
TEX@ARI | ALEJANDRO OSUNA UNDER 1.5 BASES | 54.1% | 4 | LOSS |
ATL@CHC | CHC -116 | 55.1% | 3 | WIN |
PHI@MIL | OVER 8.5 | 55.0% | 3 | WIN |
ARI@LAD | SHOHEI OHTANI OVER 2.5 BASES | 54.2% | 4 | WIN |
SEA@CLE | CLE +1.5 | 57.2% | 3 | WIN |
CHC@SF | CHC -105 | 54.1% | 4 | LOSS |
NYY@CHW | RYAN MCMAHON OVER 0.5 BASES | 54.1% | 4 | WIN |
PHI@NYM | OVER 8.5 | 55.6% | 4 | LOSS |
LAA@TEX | LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS | 54.1% | 4 | LOSS |
KC@CHW | KC -109 | 54.2% | 4 | WIN |
SD@SEA | DYLAN CEASE OVER 16.5 OUTS | 53.9% | 3 | LOSS |
SD@SEA | UNDER 8.5 | 54.4% | 4 | LOSS |
MIN@TOR | JOE RYAN UNDER 2.5 EARNED RUNS | 54.1% | 4 | LOSS |
SF@MIL | MIL +100 | 54.0% | 6 | LOSS |
TOR@MIA | MIA +1.5 | 62.0% | 6 | WIN |
CHC@LAA | OVER 9.5 | 54.9% | 4 | LOSS |
BOS@NYY | CARLOS RODON UNDER 4.5 HITS ALLOWED | 54.2% | 4 | WIN |
KC@DET | DET -115 | 56.1% | 5 | WIN |
CHC@LAA | LAA +1.5 | 57.6% | 5 | LOSS |
CIN@ARI | KEBRYAN HAYES STRIKEOUTS UNDER 0.5 | 56.2% | 6 | WIN |
LAD@SD | SD +110 | 50.9% | 6 | WIN |