Guardians vs. White Sox
Prediction, Odds & Props
Jul 11 | MLB AI Picks

Updated: 2025-07-09T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Cleveland Guardians and Chicago White Sox are set to face off on Friday, July 11, 2025, at Guaranteed Rate Field in Chicago. This matchup features two American League Central teams looking to improve their standings as the season progresses.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Jul 11, 2025

Start Time: 3:10 PM EST​

Venue: Rate Field​

White Sox Record: (31-62)

Guardians Record: (43-48)

OPENING ODDS

CLE Moneyline: -129

CHW Moneyline: +109

CLE Spread: -1.5

CHW Spread: +1.5

Over/Under: 8.5

CLE
Betting Trends

  • In their last 10 games, the Cleveland Guardians have a 7-3 record against the spread (ATS), indicating strong recent performance in covering betting lines.

CHW
Betting Trends

  • The Chicago White Sox have a 4-6 ATS record over their past 10 games, reflecting challenges in meeting betting expectations.

MATCHUP TRENDS

  • An interesting betting statistic is that the Guardians have been favored 31 times this season, winning 18 of those games, translating to a 58.1% success rate when favored.

CLE vs. CHW
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: J. Ramirez over 7.5 Fantasy Score.

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Cleveland vs Chicago White Sox Prediction & Odds:
Free MLB Betting Insights for 7/11/25

The July 11, 2025 matchup between the Cleveland Guardians and Chicago White Sox at Guaranteed Rate Field in Chicago features two American League Central clubs at opposite ends of the competitive spectrum but equally hungry for momentum as the season edges toward its latter half. The Guardians arrive with a 40-48 record and a recent string of solid performances, including a 7-3 mark against the spread in their last 10 games, reflecting both improved execution and growing confidence. With Logan Allen set to take the mound for Cleveland, they’ll look to lean on his left-handed craftiness and hope for early offense to ease the pressure on a bullpen that has shown signs of vulnerability in tight games. Allen, who enters with a 5-7 record and a 4.07 ERA, has demonstrated the ability to induce soft contact with his changeup but remains inconsistent in navigating through early innings, an issue the Guardians hope to remedy with aggressive pitch sequencing and early run support. Opposing him will be Jonathan Cannon, a right-hander with a 3-7 record and a 4.50 ERA, who has found rhythm recently, particularly in his last outing where he allowed just two runs over 5.1 innings. Cannon features a diverse repertoire highlighted by a sharp cutter and an improving sweeper, giving him tools to keep Cleveland’s lineup off balance if he can locate effectively and avoid deep counts.

The Guardians’ offense, while not overpowering, has been anchored by José Ramírez, who continues to be the engine of their attack with a .301 average and 14 home runs, providing both pop and situational hitting acumen. Meanwhile, the White Sox, sitting at a disappointing 10-27, are seeking any source of inspiration to spark a turnaround, and Friday may offer just that as the club celebrates the 20th anniversary of its 2005 World Series championship, bringing back icons like Paul Konerko and Mark Buehrle to rekindle memories and inject energy into a fan base desperate for better days. Offensively, Chicago has had limited success, averaging just 3.6 runs per game over their last 10 contests, and much of their production has come from a few standouts like Andrew Benintendi and Miguel Vargas, both with 10 home runs and modest RBI totals. Defensively, the White Sox must clean up mental lapses and support Cannon with error-free play, while their bullpen, which has struggled to protect leads, must rise to the occasion against a Guardians team that thrives in late-game execution. The key battlegrounds will be early command from both starters, situational hitting with runners in scoring position, and bullpen stamina in what could be a closely contested affair. If Cleveland can jump on Cannon early and give Allen a cushion to work with, they’ll be in good shape to take a commanding lead in the series. However, the emotional spark of a commemorative evening and the urgency of snapping a losing skid could give Chicago just enough edge to challenge a Guardians team still finding its identity. With stakes high and storylines rich, this AL Central clash promises drama, determination, and a tightrope walk between opportunity and disappointment for both clubs.

Cleveland Guardians MLB Preview

The Cleveland Guardians enter Friday night’s matchup against the Chicago White Sox with a 40-48 record and a growing sense of urgency as they attempt to claw their way back into relevance within a still-winnable American League Central division. Despite being below .500, Cleveland’s recent 7-3 performance against the spread in their last 10 games has revealed signs of grit and a more consistent approach, particularly in how they’ve managed to stay competitive in close contests. Logan Allen is slated to start on the mound and will be a focal point for the Guardians’ game plan, bringing a 5-7 record and 4.07 ERA into the outing. Allen is a lefty who relies heavily on a deceptive changeup and sharp command of the zone, but his early-inning command has wavered at times, occasionally allowing opponents to jump ahead before he settles in. To be successful, he’ll need to neutralize Chicago’s few power threats like Miguel Vargas and Andrew Benintendi by mixing speeds and working the edges of the strike zone. Behind Allen is a Cleveland bullpen that has been competent but occasionally erratic, with late-game control issues surfacing in multiple one-run losses earlier in the season. The Guardians’ offensive production remains modest, averaging about 3 runs per game over their last 10 outings, but the lineup is headlined by the consistent excellence of José Ramírez, who boasts a .301 batting average and 14 home runs while continuing to serve as the heartbeat of the lineup.

Supporting pieces like Josh Naylor and Brayan Rocchio have contributed in streaks, but Cleveland still struggles with timely hitting and capitalizing on scoring opportunities with runners in position. Managerial strategies have leaned conservative but fundamentally sound, with a focus on manufacturing runs rather than relying on the long ball, a style that matches well against a White Sox team vulnerable to sustained pressure. The Guardians have also performed relatively well when favored, winning 18 of 31 games in that role, giving bettors a reason to stay interested when the matchup leans in their favor. Friday’s contest presents a crucial opportunity not only to take a road series but also to build momentum heading into the second half of the season, especially against a division rival experiencing internal and external struggles. The Guardians’ path to victory lies in executing a clean game—efficient starting pitching, shutdown bullpen innings, and capitalizing on defensive lapses from the White Sox. With Chicago’s roster lacking consistency and the Guardians trending in the right direction, Allen’s ability to deliver a quality start and avoid big innings could be the difference. Add in Ramírez’s veteran poise and ability to change a game with a single swing or clutch base hit, and Cleveland has the personnel and poise to take control early and dictate pace. As long as the Guardians stay disciplined at the plate, execute with runners on, and maintain bullpen composure, they should walk away with a hard-earned road win and keep their divisional aspirations alive as the summer schedule heats up.

The Cleveland Guardians and Chicago White Sox are set to face off on Friday, July 11, 2025, at Guaranteed Rate Field in Chicago. This matchup features two American League Central teams looking to improve their standings as the season progresses. Cleveland vs Chicago White Sox AI Prediction: Free MLB Betting Insights for Jul 11. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Chicago White Sox White Sox MLB Preview

The Chicago White Sox return to Guaranteed Rate Field on July 11, 2025, looking to make a statement in front of their home crowd as they celebrate the 20th anniversary of their historic 2005 World Series championship. Despite a dismal 10-27 record that has placed them firmly at the bottom of the AL Central standings, this game represents more than just a divisional contest—it’s an opportunity to reignite pride, rally the fan base, and perhaps begin rewriting the narrative of a lost season. Set to start for the Sox is right-hander Jonathan Cannon, who brings a 3-7 record and 4.50 ERA into the game, but whose recent outings have shown encouraging signs of maturity and command. Cannon’s last start, a 5.1-inning effort against the Rockies where he allowed just two runs, demonstrated his ability to keep opponents off balance using a five-pitch mix including a cutter, sinker, changeup, four-seam fastball, and sweeper. For Chicago to stand a chance against Cleveland, Cannon will need to work efficiently, avoid walks, and induce weak contact, especially against the middle of the Guardians’ lineup anchored by José Ramírez. Offensively, the White Sox have been plagued by inconsistency, averaging just 3.6 runs over their last 10 games while batting .220 as a team, but they do have a few productive bats worth noting. Andrew Benintendi and Miguel Vargas have been the most dependable offensive players, each hitting 10 home runs and tallying over 30 RBIs, though much of their damage has come sporadically rather than through sustained rallies.

The supporting cast, including players like Lenyn Sosa and Korey Lee, has shown flashes but lacks the experience or polish to carry the lineup through slumps. Defensively, the White Sox must play clean, error-free baseball—something that has been difficult for them all season—with lapses in the field often compounding the effects of poor pitching and missed offensive chances. The bullpen, while occasionally competent, has also struggled to hold narrow leads or keep games close, meaning the pressure is on Cannon to pitch deep into the game. The emotional significance of Friday’s game, with former legends returning to the ballpark and a celebratory atmosphere in the stands, could provide an intangible spark for a team desperate for something positive. However, translating energy into execution remains the biggest hurdle for a club that has found it hard to string together wins or consistent performances on either side of the ball. If the White Sox can give Cannon early run support, avoid costly defensive miscues, and get timely hits in pressure situations, they have the potential to pull off an upset against a Cleveland team with more polish but also exploitable flaws. The key will be discipline at the plate, aggressive baserunning when opportunities arise, and strategic bullpen management if the game stays close into the later innings. While their recent 4-6 record against the spread doesn’t inspire overwhelming betting confidence, the White Sox have shown just enough fight to suggest that a determined, inspired performance is not out of the question in what could be their most emotionally charged home game of the season.

Cleveland vs. Chicago White Sox Prop Picks (AI)

AI algorithm Remi is pouring through tons of datapoints on each team. In fact, anytime the Guardians and White Sox play there’s always several intriguing trends to key in on. Not to mention games played at Rate Field in Jul can often follow normal, predictable patterns.
Remi's searched hard and found the best prop for this matchup: J. Ramirez over 7.5 Fantasy Score.

Cleveland vs. Chicago White Sox Prediction (AI)

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Remi, our AI sports genius, has been pouring over millions of data from every past game between the Guardians and White Sox and using recursive machine learning and kick-ass AI to boil down the data to a single cover probability.

Interestingly enough, the data has been most fixated on the unproportionally assigned emphasis knucklehead sportsbettors often put on Chicago White Sox’s strength factors between a Guardians team going up against a possibly tired White Sox team. In reality, the true game analytics appear to reflect a slight lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI Cleveland vs Chicago White Sox picks, computer picks Guardians vs White Sox, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
MLB 9/26 DET@BOS UNLOCK THIS PICK 5 EXECUTIVE Locked EXECUTIVE
MLB 9/26 BAL@NYY UNLOCK THIS PICK 4 INTEL Locked INTEL
MLB 9/26 ARI@SD UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
MLB 9/26 NYM@MIA UNLOCK THIS PICK 1 INTEL Locked INTEL
MLB 9/26 NYM@MIA GET FREE PICK NOW 1
MLB 9/26 COL@SF UNLOCK THIS PICK 0 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

Guardians Betting Trends

In their last 10 games, the Cleveland Guardians have a 7-3 record against the spread (ATS), indicating strong recent performance in covering betting lines.

White Sox Betting Trends

The Chicago White Sox have a 4-6 ATS record over their past 10 games, reflecting challenges in meeting betting expectations.

Guardians vs. White Sox Matchup Trends

An interesting betting statistic is that the Guardians have been favored 31 times this season, winning 18 of those games, translating to a 58.1% success rate when favored.

Cleveland vs. Chicago White Sox Game Info

Cleveland vs Chicago White Sox starts on July 11, 2025 at 3:10 PM EST.

Spread: Chicago White Sox +1.5
Moneyline: Cleveland -129, Chicago White Sox +109
Over/Under: 8.5

Cleveland: (43-48)  |  Chicago White Sox: (31-62)

Remi's searched hard and found the best prop for this matchup: J. Ramirez over 7.5 Fantasy Score.. Prices move—always shop for the best number.

An interesting betting statistic is that the Guardians have been favored 31 times this season, winning 18 of those games, translating to a 58.1% success rate when favored.

CLE trend: In their last 10 games, the Cleveland Guardians have a 7-3 record against the spread (ATS), indicating strong recent performance in covering betting lines.

CHW trend: The Chicago White Sox have a 4-6 ATS record over their past 10 games, reflecting challenges in meeting betting expectations.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

Cleveland vs. Chicago White Sox Odds

AI algorithm Remi is pouring through loads of data points on each team. In fact, anytime the Cleveland vs Chicago White Sox trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme hostile environments rarely follow normal, predictable betting trends.

Cleveland vs Chicago White Sox Opening Odds

CLE Moneyline: -129
CHW Moneyline: +109
CLE Spread: -1.5
CHW Spread: +1.5
Over/Under: 8.5

Cleveland vs Chicago White Sox Live Odds

Games PTS ML SPR O/U
Sep 27, 2025 1:06PM EDT
Baltimore Orioles
New York Yankees
9/27/25 1:06PM
Orioles
Yankees
+194
-235
+1.5 (-105)
-1.5 (-114)
O 8.5 (-122)
U 8.5 (+100)
Sep 27, 2025 2:21PM EDT
St Louis Cardinals
Chicago Cubs
9/27/25 2:21PM
Cardinals
Cubs
 
-168
 
-1.5 (+118)
O 9 (-122)
U 9 (+100)
Sep 27, 2025 3:09PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/27/25 3:09PM
Rays
Blue Jays
+132
-156
+1.5 (-154)
-1.5 (+128)
O 8.5 (-106)
U 8.5 (-114)
Sep 27, 2025 4:06PM EDT
Chicago White Sox
Washington Nationals
9/27/25 4:06PM
White Sox
Nationals
+102
-120
-1.5 (+162)
+1.5 (-196)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 4:06PM EDT
Colorado Rockies
San Francisco Giants
9/27/25 4:06PM
Rockies
Giants
+198
-240
+1.5 (-110)
-1.5 (-110)
O 8 (-108)
U 8 (-112)
Sep 27, 2025 4:11PM EDT
New York Mets
Miami Marlins
9/27/25 4:11PM
Mets
Marlins
-124
+106
-1.5 (+130)
+1.5 (-156)
O 8.5 (-112)
U 8.5 (-108)
Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
+177
-197
+1.5 (-118)
-1.5 (-102)
O 8.5 (-118)
U 8.5 (-102)
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
+128
-152
+1.5 (-178)
-1.5 (+146)
O 7.5 (-120)
U 7.5 (-102)
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
+143
-158
+1.5 (-150)
-1.5 (+130)
O 8.5 (+100)
U 8.5 (-120)
Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
+132
-156
+1.5 (-172)
-1.5 (+142)
O 7 (-120)
U 7 (-102)
Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
+120
-132
+1.5 (-180)
-1.5 (+157)
O 7.5 (-115)
U 7.5 (-105)
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
+102
-120
+1.5 (-215)
-1.5 (+180)
O 7.5 (-110)
U 7.5 (-110)
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
+104
-115
+1.5 (-185)
-1.5 (+161)
O 10 (-110)
U 10 (-110)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Cleveland Guardians vs. Chicago White Sox White Sox on July 11, 2025 at Rate Field.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS
CIN@ARI KEBRYAN HAYES STRIKEOUTS UNDER 0.5 56.2% 6 WIN
LAD@SD SD +110 50.9% 6 WIN