Diamondbacks vs. Padres
Prediction, Odds & Props
Jul 10 | MLB AI Picks

Updated: 2025-07-08T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Arizona Diamondbacks and San Diego Padres will conclude their four-game series on Thursday, July 10, 2025, at Petco Park in San Diego. The Diamondbacks currently lead the series 2-1 and aim to secure a series win, while the Padres look to even the series before the All-Star break.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Jul 10, 2025

Start Time: 9:40 PM EST​

Venue: Petco Park​

Padres Record: (49-43)

Diamondbacks Record: (46-47)

OPENING ODDS

ARI Moneyline: -123

SD Moneyline: +103

ARI Spread: -1.5

SD Spread: +1.5

Over/Under: 8.5

ARI
Betting Trends

  • The Diamondbacks have struggled against the spread (ATS) recently, going 1-4 in their last five games. However, they have been more successful on the road, covering the spread in five of their last seven away games.

SD
Betting Trends

  • The Padres have been inconsistent ATS at home, with a 2-5 record in their last seven games at Petco Park. Despite this, they have won four of their last five home games straight up (SU), indicating strong overall performance at home.

MATCHUP TRENDS

  • In the last 18 meetings between these two teams at Petco Park, the Diamondbacks have covered the spread 13 times. Additionally, the total has gone over in each of the last five games played between these teams in San Diego.

ARI vs. SD
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: E. Suarez over 5.5 Fantasy Score.

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Arizona vs San Diego Prediction & Odds:
Free MLB Betting Insights for 7/10/25

The Arizona Diamondbacks and San Diego Padres wrap up their four-game set on Thursday, July 10, 2025, at Petco Park in what promises to be a pivotal contest for two National League clubs hovering around the playoff race as the All-Star break approaches. Arizona enters the game with a 46–47 record and a chance to take the series after winning two of the first three games, including an emotional comeback win that saw them rally from five runs down in the ninth inning earlier this week. That victory sparked renewed energy within a D-backs squad that has been searching for consistency and offensive balance all season, with Josh Naylor and Ketel Marte emerging as the driving forces of the lineup. Marte’s switch-hitting versatility and Naylor’s raw power have given Arizona more dimension at the plate, even as the team continues to work through pitching inconsistencies. Eduardo Rodriguez is the projected starter for the Diamondbacks, and while his ERA has hovered uncomfortably near the six mark at 5.78, he has shown flashes of the veteran composure needed to survive in tough road environments. The Padres, on the other hand, are looking to even the series and improve on their solid 49–43 overall record, which has been buoyed by a 28–17 mark at Petco Park. Their offense continues to be led by the likes of Fernando Tatis Jr., Manny Machado, and Xander Bogaerts, each capable of turning a game with one swing, while Randy Vasquez is slated to start and brings a respectable 3.79 ERA across 11 starts.

San Diego has been dominant at home thanks to quality bullpen depth, timely hitting, and improved plate discipline in the middle of the order. Their recent stretch has included four wins in their last five home games, showing a level of comfort and rhythm playing in front of the home crowd. The Padres’ bullpen, anchored by relievers like Robert Suarez and Yuki Matsui, has proven adept at closing out tight games, which could be critical in what’s expected to be a close matchup. Arizona’s road record has improved lately, and they’ve managed to cover the run line in five of their last seven away games, while history shows they’ve actually covered in 13 of their last 18 visits to Petco Park. This points to a sneaky competitive edge for the Diamondbacks even as the Padres remain favorites on paper. The key matchup to watch will be Arizona’s top of the order against Vasquez early—if the Diamondbacks can push pitch counts and find traffic on the bases before the Padres’ bullpen enters, they may have a shot at clinching the series. Conversely, if San Diego’s rotation continues to deliver strong starts and the offense strikes first, the pressure may fall heavily on Arizona’s bullpen, which has been far more volatile. With postseason implications already creeping into focus and two clubs desperate to stay above .500, Thursday’s series finale sets up as a tightly contested, potentially season-defining battle in the NL West race.

Arizona Diamondbacks MLB Preview

The Arizona Diamondbacks head into Thursday’s series finale at Petco Park sitting just below the .500 mark with a 46–47 record, but with a chance to secure a meaningful road series win against a divisional rival in the San Diego Padres. This team has been one of the more enigmatic squads in the National League this year—at times flashing postseason-caliber offense, while at other moments unraveling due to pitching inconsistencies and lackluster situational hitting. Josh Naylor has become the offensive cornerstone for Arizona, leading the club with a .303 average and delivering both timely power and on-base efficiency in the heart of the order. Ketel Marte remains one of the most valuable switch-hitters in the league, providing lineup flexibility and consistent contact that Arizona desperately leans on during low-scoring stretches. Geraldo Perdomo’s emergence in the middle infield has also been a welcome surprise, especially given his knack for getting on base and scoring runs. However, it’s the pitching that continues to define the ceiling of this roster. Eduardo Rodriguez, Thursday’s projected starter, has endured a rocky 2025 campaign marked by a 3–5 record and 5.78 ERA, frequently struggling with command and giving up hard contact early in games. His ability to find the strike zone early and induce ground balls will be pivotal against a disciplined Padres lineup.

The bullpen has had its own issues, ranking in the bottom third of the National League in ERA, and too often has allowed inherited runners to score, undermining strong outings from the rotation. That said, the Diamondbacks have shown mental toughness on the road recently, including a dramatic ninth-inning rally earlier in this series, which speaks to the resilience manager Torey Lovullo has instilled in the clubhouse. While their overall road record is middling, they’ve quietly covered the spread in five of their last seven road games and historically perform well at Petco Park, covering in 13 of their last 18 games in San Diego. Offensively, the Diamondbacks will need to stay patient at the plate, extending at-bats and working counts to get into the Padres’ bullpen early, where matchups may tilt slightly in Arizona’s favor. Defensively, the team has been efficient with minimal errors, but has struggled to contain the running game—a vulnerability that San Diego could exploit. If Rodriguez can deliver a serviceable start and Arizona’s bats can cash in with runners in scoring position, the Diamondbacks have the tools to pull off another series win and gain valuable momentum heading into the All-Star break. But if they fall behind early or continue their bullpen woes, they’ll likely fall back into the familiar territory of near-miss mediocrity that has dogged them all season. For a team still clinging to wildcard aspirations in a wide-open NL playoff chase, this game represents more than just a single win—it’s a tone-setting opportunity to show they can compete and close out tough series on the road.

The Arizona Diamondbacks and San Diego Padres will conclude their four-game series on Thursday, July 10, 2025, at Petco Park in San Diego. The Diamondbacks currently lead the series 2-1 and aim to secure a series win, while the Padres look to even the series before the All-Star break. Arizona vs San Diego AI Prediction: Free MLB Betting Insights for Jul 10. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

San Diego Padres MLB Preview

The San Diego Padres enter the final game of this crucial four-game series against the Arizona Diamondbacks with a solid 49–43 record, looking to avoid dropping the series at home and instead close it with a split before heading into the All-Star break. Having gone 28–17 at Petco Park this season, the Padres have found comfort and rhythm in front of their home crowd, thanks to a roster that blends experienced stars with emerging talent. Offensively, San Diego continues to be powered by the steady production of Fernando Tatis Jr., who remains one of the most dangerous hitters in the National League with his mix of speed, power, and defensive brilliance in the outfield. Manny Machado and Xander Bogaerts have both turned it up in recent weeks, providing protection and clutch hitting behind Tatis while also forming a veteran core that stabilizes the clubhouse. Jake Cronenworth’s reliable bat and versatility in the infield add further depth to an offense that ranks in the top third of the NL in runs scored. On the mound, right-hander Randy Vasquez is the scheduled starter, carrying a 3–4 record with a strong 3.79 ERA, showing poise and control in what’s shaping up to be a breakout year. His ability to mix pitches effectively and generate ground balls makes him a solid matchup against a Diamondbacks team that leans on contact rather than overwhelming power. Defensively, the Padres have been tight, ranking among the better teams in fielding percentage while limiting extra-base hits in large Petco Park.

Their bullpen, anchored by closer Robert Suarez and setup man Yuki Matsui, has become a strength late in games, holding leads and stranding runners in key moments. One potential challenge lies in the starting pitching’s ability to go deep into games—San Diego’s middle relief has been shaky at times, so Vasquez’s first five innings will be critical. The Padres have also seen the total go over in many recent home games, a sign that while their offense is clicking, their pitching staff can allow enough damage to force high-scoring affairs. Manager Mike Shildt has done well to keep this group competitive in a tight NL West and is expected to lean heavily on his big bats early to avoid falling behind. Historically, the Padres have not dominated Arizona at home ATS, covering in just 5 of the last 18 matchups at Petco Park, but they’ve won four of their last five overall at home and have been one of the NL’s best teams when scoring first. If the Padres can get early production from the top of the order and limit free passes from Vasquez, they’re in a strong position to take Thursday’s finale and head into the break with momentum. More than just another regular-season game, this matchup represents a measuring stick for San Diego’s postseason readiness, as they look to prove that they can close out tough, playoff-caliber opponents and establish dominance on their home field.

Arizona vs. San Diego Prop Picks (AI)

AI algorithm Remi is pouring through loads of stats on each line. In fact, anytime the Diamondbacks and Padres play there’s always several intriguing angles to key in on. Not to mention games played at Petco Park in Jul can often follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: E. Suarez over 5.5 Fantasy Score.

Arizona vs. San Diego Prediction (AI)

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Remi, our AI sports genius, has been pouring over millions of data from every past game between the Diamondbacks and Padres and using recursive machine learning and industry leading AI to crunch the data to a single cover probability.

Remi has been most fixated on the growing factor knucklehead sportsbettors regularly put on coaching factors between a Diamondbacks team going up against a possibly improved Padres team. Trends look to say the true game analytics might reflect a strong lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI Arizona vs San Diego picks, computer picks Diamondbacks vs Padres, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
MLB 9/26 DET@BOS UNLOCK THIS PICK 5 EXECUTIVE Locked EXECUTIVE
MLB 9/26 BAL@NYY UNLOCK THIS PICK 4 INTEL Locked INTEL
MLB 9/26 ARI@SD UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
MLB 9/26 NYM@MIA UNLOCK THIS PICK 1 INTEL Locked INTEL
MLB 9/26 NYM@MIA GET FREE PICK NOW 1
MLB 9/26 COL@SF UNLOCK THIS PICK 0 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

Diamondbacks Betting Trends

The Diamondbacks have struggled against the spread (ATS) recently, going 1-4 in their last five games. However, they have been more successful on the road, covering the spread in five of their last seven away games.

Padres Betting Trends

The Padres have been inconsistent ATS at home, with a 2-5 record in their last seven games at Petco Park. Despite this, they have won four of their last five home games straight up (SU), indicating strong overall performance at home.

Diamondbacks vs. Padres Matchup Trends

In the last 18 meetings between these two teams at Petco Park, the Diamondbacks have covered the spread 13 times. Additionally, the total has gone over in each of the last five games played between these teams in San Diego.

Arizona vs. San Diego Game Info

Arizona vs San Diego starts on July 10, 2025 at 9:40 PM EST.

Spread: San Diego +1.5
Moneyline: Arizona -123, San Diego +103
Over/Under: 8.5

Arizona: (46-47)  |  San Diego: (49-43)

Remi's searched hard and found the best prop for this matchup: E. Suarez over 5.5 Fantasy Score.. Prices move—always shop for the best number.

In the last 18 meetings between these two teams at Petco Park, the Diamondbacks have covered the spread 13 times. Additionally, the total has gone over in each of the last five games played between these teams in San Diego.

ARI trend: The Diamondbacks have struggled against the spread (ATS) recently, going 1-4 in their last five games. However, they have been more successful on the road, covering the spread in five of their last seven away games.

SD trend: The Padres have been inconsistent ATS at home, with a 2-5 record in their last seven games at Petco Park. Despite this, they have won four of their last five home games straight up (SU), indicating strong overall performance at home.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

Arizona vs. San Diego Odds

AI algorithm Remi is pouring through tons of data points on each player. In fact, anytime the Arizona vs San Diego trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme travel distance rarely follow normal, predictable betting trends.

Arizona vs San Diego Opening Odds

ARI Moneyline: -123
SD Moneyline: +103
ARI Spread: -1.5
SD Spread: +1.5
Over/Under: 8.5

Arizona vs San Diego Live Odds

Games PTS ML SPR O/U
Sep 27, 2025 1:06PM EDT
Baltimore Orioles
New York Yankees
9/27/25 1:06PM
Orioles
Yankees
+196
-240
+1.5 (-110)
-1.5 (-110)
O 8.5 (-120)
U 8.5 (+100)
Sep 27, 2025 2:21PM EDT
St Louis Cardinals
Chicago Cubs
9/27/25 2:21PM
Cardinals
Cubs
 
-178
 
-1.5 (+115)
O 9.5 (-105)
U 9.5 (-115)
Sep 27, 2025 3:09PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/27/25 3:09PM
Rays
Blue Jays
+135
-160
+1.5 (-160)
-1.5 (+135)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 4:06PM EDT
Chicago White Sox
Washington Nationals
9/27/25 4:06PM
White Sox
Nationals
+100
-120
+1.5 (-205)
-1.5 (+170)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 4:06PM EDT
Colorado Rockies
San Francisco Giants
9/27/25 4:06PM
Rockies
Giants
+192
-235
+1.5 (-110)
-1.5 (-110)
O 8 (-105)
U 8 (-115)
Sep 27, 2025 4:11PM EDT
New York Mets
Miami Marlins
9/27/25 4:11PM
Mets
Marlins
-130
+110
-1.5 (+130)
+1.5 (-155)
O 8 (-115)
U 8 (-105)
Sep 27, 2025 4:11PM EDT
Detroit Tigers
Boston Red Sox
9/27/25 4:11PM
Tigers
Red Sox
+130
-155
+1.5 (-170)
-1.5 (+140)
O 9 (-105)
U 9 (-115)
Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
+170
-205
+1.5 (-120)
-1.5 (+100)
O 8.5 (-120)
U 8.5 (+100)
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
+130
-155
+1.5 (-170)
-1.5 (+143)
O 7.5 (-120)
U 7.5 (+100)
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
+150
-178
+1.5 (-145)
-1.5 (+122)
O 8 (-110)
U 8 (-110)
Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
+135
-160
+1.5 (-170)
-1.5 (+143)
O 7 (-120)
U 7 (+100)
Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
+118
-140
+1.5 (-190)
-1.5 (+158)
O 7.5 (-115)
U 7.5 (-105)
Sep 27, 2025 9:39PM EDT
Houston Astros
Los Angeles Angels
9/27/25 9:39PM
Astros
Angels
-155
+130
-1.5 (+110)
+1.5 (-130)
O 9 (-110)
U 9 (-110)
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
+105
-125
+1.5 (-205)
-1.5 (+170)
O 7 (-120)
U 7 (+100)
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
+100
-120
+1.5 (-195)
-1.5 (+162)
O 10 (-110)
U 10 (-110)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Arizona Diamondbacks vs. San Diego Padres on July 10, 2025 at Petco Park.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS
CIN@ARI KEBRYAN HAYES STRIKEOUTS UNDER 0.5 56.2% 6 WIN
LAD@SD SD +110 50.9% 6 WIN