Guardians vs. Astros
Prediction, Odds & Props
Jul 08 | MLB AI Picks

Updated: 2025-07-06T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Houston Astros (55–36) host the Cleveland Guardians (41–48) on Tuesday, July 8, 2025, at Daikin Park in Houston. The Astros aim to continue their strong home performance, while the Guardians look to break their recent losing streak.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Jul 08, 2025

Start Time: 8:10 PM EST​

Venue: Daikin Park​

Astros Record: (55-36)

Guardians Record: (41-48)

OPENING ODDS

CLE Moneyline: +170

HOU Moneyline: -206

CLE Spread: +1.5

HOU Spread: -1.5

Over/Under: 7

CLE
Betting Trends

  • The Guardians have struggled against the spread (ATS) recently, with a 1–4 record in their last five games.

HOU
Betting Trends

  • The Astros have a 3–2 ATS record over their past five games, reflecting a solid performance in covering the spread.

MATCHUP TRENDS

  • In their last three head-to-head matchups, the Astros have won two games against the Guardians, suggesting a recent advantage in this series.

CLE vs. HOU
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: M. Dubon over 3 Fantasy Score.

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Cleveland vs Houston Prediction & Odds:
Free MLB Betting Insights for 7/8/25

The Houston Astros and Cleveland Guardians face off on Tuesday, July 8, 2025, at Daikin Park in Houston in a matchup that pits one of the American League’s most consistent contenders against a struggling club trying to regain its footing. With the Astros boasting a 55–36 record and the Guardians floundering at 41–48 amidst a 10-game losing streak, this game shapes up as a potential mismatch—yet one that Cleveland will be desperate to use as a turning point before the All-Star break. The Astros have won eight of their last ten and come into the game with a 32–14 home record, using their familiar ballpark and crowd energy to power an offense led by José Altuve, Isaac Paredes, and Yordan Alvarez, who has recently returned to form after battling injuries earlier this season. Their pitching staff has also performed at a high level, especially Hunter Brown, who leads the team with a dazzling 1.82 ERA and has become one of the best young starters in the league. The bullpen, anchored by closer Ryan Pressly and setup man Bryan Abreu, has held firm in late innings and helped Houston win a multitude of close games. Defensively, Houston remains one of the cleanest teams in the majors, rarely giving away extra outs and making plays that kill rallies before they start.

In contrast, the Guardians are limping into this game both figuratively and literally, with their lineup failing to consistently produce despite the best efforts of José Ramírez, who continues to be one of the few bright spots on an underwhelming roster. Ramírez, batting .297 with 14 home runs, has received little support from a lineup plagued by injuries and inconsistency, while rookie starter Joey Cantillo, expected to get the nod, faces an incredibly tough task against Houston’s lineup. Cleveland’s pitching staff has largely underwhelmed in 2025, and while closer Emmanuel Clase remains elite, the bridge from starter to closer has been unreliable, with middle relief allowing too many inherited runners to score. The Guardians’ defense has also been average at best, with infield errors and shaky outfield play contributing to extended innings and elevated pitch counts. While the team has managed just one ATS cover in its last five games, it has hung tough in a few recent contests and could keep things competitive if Cantillo can avoid early damage and if Ramírez and Steven Kwan can ignite the offense. Still, with the Astros clicking in every facet of the game and having won two of the last three meetings between these teams, they are firmly in control entering this contest. For Cleveland to reverse the script, they’ll need a perfect storm—dominant pitching, timely hitting, and mistake-free defense—while Houston simply needs to keep doing what it’s been doing. If the Astros jump out to an early lead, it could turn into another long night for a Guardians squad running out of answers, while a strong start from Cantillo could at least offer a glimpse of hope that the losing streak can finally be snapped.

Cleveland Guardians MLB Preview

The Cleveland Guardians enter Tuesday’s clash against the Houston Astros mired in a deep slump, having dropped ten consecutive games to fall to 41–48 on the season and drift further out of contention in the American League Central. Despite their current record, there are still key contributors trying to keep the club afloat, most notably perennial MVP candidate José Ramírez, who is hitting .297 with 14 home runs and continues to be a steady force in the heart of the lineup. However, Ramírez has lacked consistent support from the rest of the batting order, as the team ranks in the bottom tier of the league in several offensive categories including team batting average and slugging percentage. Josh Naylor has been inconsistent, while players like Steven Kwan and Bo Naylor have had moments but haven’t been able to sustain production through the lineup. As they face one of the top rotations in the league in Houston, Cleveland’s offensive inconsistencies could once again be exposed if they’re unable to string together timely hits. Joey Cantillo is expected to get the start for the Guardians, and although he brings intriguing upside as a left-handed arm with strikeout ability, his MLB experience is limited and he’s still working through growing pains at the highest level.

Cleveland’s bullpen, once a team strength, has regressed this season with the exception of closer Emmanuel Clase, who continues to be elite in save situations but hasn’t had many recent opportunities to make an impact. The middle relief corps has struggled mightily to keep games close, and defensive lapses—especially infield errors and misplays in the outfield—have compounded those issues and led to extended innings and unearned runs. The Guardians have also struggled on the road, and with a 1–4 ATS record in their last five games, bettors and fans alike have had little reason to back them with confidence. Manager Stephen Vogt continues to focus on development and finding consistency from young players, giving opportunities to rising prospects but paying the price with uneven play and mental mistakes. Facing an Astros team that is dominant at home and currently firing on all cylinders both at the plate and on the mound, Cleveland will need a nearly perfect performance from Cantillo and a spark from its underachieving offense to avoid a sweep or blowout loss. The key for the Guardians will be keeping the game close through five innings, hoping for a standout outing from Ramírez or a surprise performance from someone lower in the order like Will Brennan or Andrés Giménez to generate offensive momentum. Still, with morale low and confidence shaken, the Guardians must dig deep to turn their fortunes around, and Tuesday’s matchup, although daunting, offers them an opportunity to show resilience against a high-caliber opponent and potentially begin clawing their way back into relevance before the season slips away completely.

The Houston Astros (55–36) host the Cleveland Guardians (41–48) on Tuesday, July 8, 2025, at Daikin Park in Houston. The Astros aim to continue their strong home performance, while the Guardians look to break their recent losing streak. Cleveland vs Houston AI Prediction: Free MLB Betting Insights for Jul 08. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Houston Astros MLB Preview

The Houston Astros come into Tuesday’s matchup against the Cleveland Guardians playing some of their best baseball of the 2025 season, having won eight of their last ten games to surge to a 55–36 record and reestablish their dominance in the AL West. Led by a veteran core and a new wave of contributors, the Astros continue to thrive under pressure, particularly at Daikin Park, where they’ve posted an imposing 32–14 home record this year. Offensively, the club is anchored by the ever-reliable José Altuve, who remains the tone-setter at the top of the order, while Isaac Paredes has provided a significant boost to the middle of the lineup with timely power and run production. Yordan Alvarez, who recently returned to the lineup following earlier injury concerns, has already begun to reassert himself as one of the most feared left-handed hitters in baseball, and with Kyle Tucker and Jeremy Peña also contributing, the Astros boast one of the deepest and most balanced lineups in the league. On the mound, the rotation has been led by Hunter Brown, who continues to dazzle with a 9–3 record and a 1.82 ERA, and while he’s not expected to start this matchup, the rest of the staff—including Framber Valdez and Cristian Javier—has provided consistent quality starts, minimizing the strain on a talented bullpen.

Closer Ryan Pressly has been rock solid in the ninth inning, while Bryan Abreu and Rafael Montero give manager Joe Espada reliable options in high-leverage situations. Houston’s defense has also played a key role in their success, with the infield flashing excellent range and sure-handedness, and the outfield tracking balls with precision, allowing the pitching staff to pitch to contact with confidence. Against the Guardians, who have dropped ten straight and are sputtering offensively, the Astros have a prime opportunity to continue building momentum heading into the All-Star break. They’ve already taken two of the last three head-to-head matchups against Cleveland and appear well-positioned to exploit a shaky Guardians bullpen and a lineup that has struggled mightily outside of José Ramírez. For Houston, the keys to victory will likely lie in jumping out to an early lead and forcing Cleveland to play from behind—a situation they’ve rarely handled well during their recent skid. The Astros’ situational hitting, aggressive baserunning, and clean defense should provide them with a significant edge, particularly at home where they’ve excelled in every phase of the game. With a 3–2 ATS mark in their last five contests and playoff positioning increasingly in focus, expect a disciplined, methodical effort from Houston as they seek to capitalize on a vulnerable opponent and pad their divisional lead. As long as they avoid overlooking a wounded Cleveland team, the Astros should have the advantage in every key matchup and remain one of the most complete and dangerous teams in baseball entering the back half of the season.

Cleveland vs. Houston Prop Picks (AI)

AI algorithm Remi is pouring through loads of data on each team. In fact, anytime the Guardians and Astros play there’s always several intriguing angles to key in on. Not to mention games played at Daikin Park in Jul almost always follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: M. Dubon over 3 Fantasy Score.

Cleveland vs. Houston Prediction (AI)

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Remi, our AI sports wizard, has been pouring over millions of data from every simulation between the Guardians and Astros and using recursive machine learning and impressive AI to crunch the data to a single cover probability.

Oddly enough, we’ve seen the AI has been most fixated on the growing weight knucklehead sportsbettors often put on coaching factors between a Guardians team going up against a possibly healthy Astros team. We’ve found the true game analytics appear to reflect a strong lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI Cleveland vs Houston picks, computer picks Guardians vs Astros, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
MLB 9/26 DET@BOS UNLOCK THIS PICK 5 EXECUTIVE Locked EXECUTIVE
MLB 9/26 BAL@NYY UNLOCK THIS PICK 4 INTEL Locked INTEL
MLB 9/26 ARI@SD UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
MLB 9/26 NYM@MIA UNLOCK THIS PICK 1 INTEL Locked INTEL
MLB 9/26 NYM@MIA GET FREE PICK NOW 1
MLB 9/26 COL@SF UNLOCK THIS PICK 0 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

Guardians Betting Trends

The Guardians have struggled against the spread (ATS) recently, with a 1–4 record in their last five games.

Astros Betting Trends

The Astros have a 3–2 ATS record over their past five games, reflecting a solid performance in covering the spread.

Guardians vs. Astros Matchup Trends

In their last three head-to-head matchups, the Astros have won two games against the Guardians, suggesting a recent advantage in this series.

Cleveland vs. Houston Game Info

Cleveland vs Houston starts on July 08, 2025 at 8:10 PM EST.

Spread: Houston -1.5
Moneyline: Cleveland +170, Houston -206
Over/Under: 7

Cleveland: (41-48)  |  Houston: (55-36)

Remi's searched hard and found the best prop for this matchup: M. Dubon over 3 Fantasy Score.. Prices move—always shop for the best number.

In their last three head-to-head matchups, the Astros have won two games against the Guardians, suggesting a recent advantage in this series.

CLE trend: The Guardians have struggled against the spread (ATS) recently, with a 1–4 record in their last five games.

HOU trend: The Astros have a 3–2 ATS record over their past five games, reflecting a solid performance in covering the spread.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

Cleveland vs. Houston Odds

AI algorithm Remi is pouring through mountains of stats on each team. In fact, anytime the Cleveland vs Houston trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme temps rarely follow normal, predictable betting trends.

Cleveland vs Houston Opening Odds

CLE Moneyline: +170
HOU Moneyline: -206
CLE Spread: +1.5
HOU Spread: -1.5
Over/Under: 7

Cleveland vs Houston Live Odds

Games PTS ML SPR O/U
Sep 27, 2025 1:06PM EDT
Baltimore Orioles
New York Yankees
9/27/25 1:06PM
Orioles
Yankees
+194
-235
+1.5 (-105)
-1.5 (-114)
O 8.5 (-122)
U 8.5 (+100)
Sep 27, 2025 2:21PM EDT
St Louis Cardinals
Chicago Cubs
9/27/25 2:21PM
Cardinals
Cubs
 
-168
 
-1.5 (+118)
O 9 (-122)
U 9 (+100)
Sep 27, 2025 3:09PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/27/25 3:09PM
Rays
Blue Jays
+132
-156
+1.5 (-154)
-1.5 (+128)
O 8.5 (-106)
U 8.5 (-114)
Sep 27, 2025 4:06PM EDT
Chicago White Sox
Washington Nationals
9/27/25 4:06PM
White Sox
Nationals
+102
-120
-1.5 (+162)
+1.5 (-196)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 4:06PM EDT
Colorado Rockies
San Francisco Giants
9/27/25 4:06PM
Rockies
Giants
+198
-240
+1.5 (-110)
-1.5 (-110)
O 8 (-108)
U 8 (-112)
Sep 27, 2025 4:11PM EDT
New York Mets
Miami Marlins
9/27/25 4:11PM
Mets
Marlins
-124
+106
-1.5 (+130)
+1.5 (-156)
O 8.5 (-112)
U 8.5 (-108)
Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
+177
-197
+1.5 (-118)
-1.5 (-102)
O 8.5 (-118)
U 8.5 (-102)
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
+128
-152
+1.5 (-178)
-1.5 (+146)
O 7.5 (-120)
U 7.5 (-102)
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
+143
-158
+1.5 (-150)
-1.5 (+130)
O 8.5 (+100)
U 8.5 (-120)
Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
+132
-156
+1.5 (-172)
-1.5 (+142)
O 7 (-120)
U 7 (-102)
Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
+120
-132
+1.5 (-180)
-1.5 (+157)
O 7.5 (-115)
U 7.5 (-105)
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
+102
-120
+1.5 (-215)
-1.5 (+180)
O 7.5 (-110)
U 7.5 (-110)
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
+104
-115
+1.5 (-185)
-1.5 (+161)
O 10 (-110)
U 10 (-110)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Cleveland Guardians vs. Houston Astros on July 08, 2025 at Daikin Park.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS
CIN@ARI KEBRYAN HAYES STRIKEOUTS UNDER 0.5 56.2% 6 WIN
LAD@SD SD +110 50.9% 6 WIN