Tigers vs Guardians Prediction — AI Finds CAN'T MISS MLB Lines & Props (Jul 06)
Updated: 2025-07-04T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The Detroit Tigers (55–34) and Cleveland Guardians (40–46) are set to conclude their three-game series at Progressive Field on Sunday, July 6, 2025, with first pitch scheduled for 1:40 PM ET. The Tigers aim to complete the sweep, while the Guardians look to avoid a home series loss.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Jul 06, 2025
Start Time: 1:40 PM EST
Venue: Progressive Field
Guardians Record: (40-47)
Tigers Record: (56-34)
OPENING ODDS
DET Moneyline: -221
CLE Moneyline: +181
DET Spread: -1.5
CLE Spread: +1.5
Over/Under: 7.5
DET
Betting Trends
- The Tigers have been dominant against the spread (ATS) this season, boasting a 54–33 record, reflecting their consistent performance both at home and on the road.
CLE
Betting Trends
- The Guardians have struggled ATS, holding a 37–37 record, indicating inconsistency in covering the spread, particularly against strong opponents.
MATCHUP TRENDS
- In their last 10 head-to-head matchups, the Tigers have covered the spread in 7 games, showcasing their recent dominance over the Guardians.
DET vs. CLE
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: P. Meadows over 0.5 Total Bases.
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Detroit vs Cleveland Prediction & Odds:
Free MLB Betting Insights for 7/6/25
The Tigers’ bullpen has also done its part, with Will Vest posting a 2.25 ERA in 40 innings and the relief corps consistently protecting leads and closing out games with minimal drama. Cleveland, meanwhile, continues to scuffle, dropping to 40–46 on the year and sitting 12.5 games behind Detroit in the division, and the momentum clearly favors the visitors entering Sunday’s finale. The Guardians’ struggles have stemmed from both injuries and underperformance—starters Shane Bieber and Ben Lively are sidelined, and the bullpen has been shaky, regularly blowing leads and putting additional strain on a thin rotation. Offensively, José Ramírez (.299 AVG, 13 HR) and Steven Kwan (.296 AVG) have done their part, but they’ve received little help from the rest of the lineup, which has lacked both consistency and power. With their season teetering, the Guardians will turn to a starter who must provide both length and quality to keep their fading hopes afloat, but against a Tigers team that has covered the spread in seven of their last ten head-to-head matchups, that task looks formidable. If Cleveland is to salvage the series and avoid the sweep, they’ll need a crisp performance in all phases—something they haven’t been able to deliver often this year. Detroit’s recent dominance, including a 54–33 ATS record, highlights their ability to handle business against both weak and competitive teams, and with their ace on the mound and offense firing, the Tigers are clear favorites to complete the sweep and carry momentum into the second half of the season. For the Guardians, Sunday represents more than just a single game—it’s a chance to show fight, protect home field, and try to spark a turnaround before the gap in the division becomes insurmountable.
ever experienced a Tork 💣 called by @TarikSkubal?
— Detroit Tigers (@tigers) July 5, 2025
now you have pic.twitter.com/IioY3q5LJl
Detroit Tigers MLB Preview
The Detroit Tigers enter Sunday’s series finale against the Cleveland Guardians as one of the hottest teams in Major League Baseball, riding a five-game winning streak and looking to complete a convincing sweep of their division rivals at Progressive Field. At 55–34, the Tigers lead the American League Central and have built their success on a combination of dominant starting pitching, timely power hitting, and dependable defense, all of which have been on full display during their recent run. The backbone of Detroit’s surge has been left-handed ace Tarik Skubal, who will take the mound Sunday with a 10–2 record, a sparkling 2.15 ERA, and 138 strikeouts across 104.2 innings pitched. Skubal’s fastball-changeup combo has baffled hitters all season, and he’s been nearly unhittable in his last several starts, earning AL Player of the Week honors for his efforts. He’s supported by a Tigers lineup that has steadily evolved into one of the more balanced units in the league, with Riley Greene leading the charge offensively with a .290 batting average, 21 home runs, and a .931 OPS, while Spencer Torkelson adds complementary power with 19 homers and 58 RBIs.
The Tigers aren’t a team that bludgeons opponents with gaudy run totals every night, but they capitalize on mistakes, string together hits in key moments, and execute with runners in scoring position, making them especially dangerous in tight, late-game situations. Defensively, Detroit has minimized errors and played clean baseball, a critical factor in allowing their pitching staff to thrive and avoid added pressure. Their bullpen, anchored by Will Vest (2.25 ERA, 44 strikeouts in 40 innings), has emerged as one of the more underrated units in the American League, consistently holding leads and shortening games effectively. Manager A.J. Hinch has been masterful in managing his rotation, optimizing platoon matchups, and getting the most out of both young players and veterans alike. One of Detroit’s underrated strengths has been its performance against the spread; the Tigers have covered in 54 of their 87 games, including seven of their last 10 against Cleveland, proving they’re not just winning—they’re consistently outperforming expectations. Sunday offers another opportunity for Detroit to assert its dominance in the AL Central and send a message to the rest of the league that their first-half surge is no fluke. With momentum, talent, and a clear identity, the Tigers are positioned to finish this series with authority, build their division lead, and head into the All-Star break with one of the most complete resumes in baseball. If Skubal pitches to his capability and the offense continues producing at its current clip, Detroit is not only likely to win Sunday’s matchup—they could continue to widen the gap atop the division in the weeks to come.

Credit: USA TODAY/IMAGN
Cleveland Guardians MLB Preview
The Cleveland Guardians approach Sunday’s finale against the Detroit Tigers under mounting pressure, not just to avoid a sweep at home but to breathe life back into a season that’s steadily slipping out of reach. Now 40–46 and buried 12.5 games behind the Tigers in the AL Central, Cleveland finds itself at a crossroads as it stares down one of the league’s best teams and arguably the best pitcher in the American League in Tarik Skubal. The Guardians have dropped the first two games of this series by a combined margin of 11–3, further highlighting the offensive inconsistencies and pitching woes that have plagued them throughout 2025. Though they’ve been able to lean on José Ramírez, who’s hitting .299 with 13 home runs and continues to be a force in the middle of the lineup, and Steven Kwan, who’s batting .296 and providing steady production from the top of the order, there’s been little support behind them. The remainder of the batting order has struggled with timely hitting and situational execution, leading to long scoring droughts and wasted opportunities, particularly against high-quality starters like those Detroit brings to the table. Injuries have made matters worse—Cleveland’s rotation has been gutted by the absence of Shane Bieber and Ben Lively, forcing the Guardians to rely on younger, unproven arms and middle relievers to carry innings.
The bullpen, once a source of reliability, has faltered under the added strain, blowing multiple leads over the past two weeks and posting a collective ERA north of 4.50 since mid-June. Manager Stephen Vogt has experimented with lineup reshuffling and bullpen matchups, but with a roster stretched thin and confidence waning, results have been hard to come by. Defensive lapses have compounded their issues, as Cleveland ranks near the bottom of the league in fielding percentage and continues to commit costly errors that turn tight games into lopsided losses. To avoid being swept at home, the Guardians will need a breakout performance both from their starting pitcher and their offense—particularly from players like Josh Naylor and Will Brennan, who’ve shown flashes of power but haven’t delivered consistent run production lately. More than anything, the Guardians need to play with urgency and clean fundamentals, using aggressive baserunning and disciplined at-bats to put pressure on a Detroit team that has largely dictated the pace of this series. This game could serve as a pivotal moment in Cleveland’s season; a win would not only stave off the sweep but could also help spark a turnaround and instill some much-needed belief heading into the All-Star break. Conversely, another flat performance would deepen the hole they’re in and further highlight the growing divide between themselves and the division leaders. The Guardians have enough talent to be competitive, but unless they can summon a complete, mistake-free effort on Sunday, they risk becoming a non-factor in the division far earlier than anticipated.
Rough night at the ballpark.#GuardsBall pic.twitter.com/hKn6fCR60b
— Cleveland Guardians (@CleGuardians) July 6, 2025
Detroit vs. Cleveland Prop Picks (AI)
Detroit vs. Cleveland Prediction (AI)

Remi, our AI sports wizard, has been pouring over tons of data from every facet between the Tigers and Guardians and using recursive machine learning and industry leading AI to crunch the data to a single cover probability.
Interestingly enough, the data has been most fixated on the growing factor human bettors often put on Detroit’s strength factors between a Tigers team going up against a possibly rested Guardians team. We’ve found the true game analytics appear to reflect a moderate lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.
Below is our current AI Detroit vs Cleveland picks, computer picks Tigers vs Guardians, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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MLB | 10/20 | SEA@TOR | UNLOCK THIS PICK | 2 |
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MLB | 10/20 | SEA@TOR | UNLOCK THIS PICK | 0 |
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.
Tigers Betting Trends
The Tigers have been dominant against the spread (ATS) this season, boasting a 54–33 record, reflecting their consistent performance both at home and on the road.
Guardians Betting Trends
The Guardians have struggled ATS, holding a 37–37 record, indicating inconsistency in covering the spread, particularly against strong opponents.
Tigers vs. Guardians Matchup Trends
In their last 10 head-to-head matchups, the Tigers have covered the spread in 7 games, showcasing their recent dominance over the Guardians.
Detroit vs. Cleveland Game Info
What time does Detroit vs Cleveland start on July 06, 2025?
Detroit vs Cleveland starts on July 06, 2025 at 1:40 PM EST.
Where is Detroit vs Cleveland being played?
Venue: Progressive Field.
What are the opening odds for Detroit vs Cleveland?
Spread: Cleveland +1.5
Moneyline: Detroit -221, Cleveland +181
Over/Under: 7.5
What are the records for Detroit vs Cleveland?
Detroit: (56-34) | Cleveland: (40-47)
What is the AI best bet for Detroit vs Cleveland?
Remi's searched hard and found the best prop for this matchup: P. Meadows over 0.5 Total Bases.. Prices move—always shop for the best number.
What are Detroit vs Cleveland trending bets?
In their last 10 head-to-head matchups, the Tigers have covered the spread in 7 games, showcasing their recent dominance over the Guardians.
What are Detroit trending bets?
DET trend: The Tigers have been dominant against the spread (ATS) this season, boasting a 54–33 record, reflecting their consistent performance both at home and on the road.
What are Cleveland trending bets?
CLE trend: The Guardians have struggled ATS, holding a 37–37 record, indicating inconsistency in covering the spread, particularly against strong opponents.
Where can I find AI Picks for Detroit vs Cleveland?
See our latest MLB picks and odds pages for 2025 to compare prices before you bet.
Detroit vs. Cleveland Odds
AI algorithm Remi is pouring through loads of stats on each player. In fact, anytime the Detroit vs Cleveland trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme altitude can often follow normal, predictable betting trends.
Detroit vs Cleveland Opening Odds
DET Moneyline:
-221 CLE Moneyline: +181
DET Spread: -1.5
CLE Spread: +1.5
Over/Under: 7.5
Detroit vs Cleveland Live Odds
Games | PTS | ML | SPR | O/U | |
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Oct 24, 2025 8:00PM EDT
Los Angeles Dodgers
Toronto Blue Jays
10/24/25 8PM
Dodgers
Blue Jays
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–
–
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-157
+129
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-1.5 (+118)
+1.5 (-144)
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O 7.5 (+102)
U 7.5 (-125)
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MLB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Detroit Tigers vs. Cleveland Guardians on July 06, 2025 at Progressive Field.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
TOR@SEA | OVER 7 | 54.9% | 3 | WIN |
LAD@MIL | UNDER 7.5 | 56.6% | 6 | WIN |
TOR@NYY | OVER 8 | 54.9% | 4 | WIN |
TOR@NYY | CARLOS RODON OVER 1.5 TOTAL WALKS ALLOWED | 53.3% | 3 | WIN |
NYY@TOR | OVER 7.5 | 54.8% | 2 | WIN |
LAD@PHI | OVER 7 | 53.8% | 3 | WIN |
SD@CHC | CHC -109 | 53.8% | 3 | WIN |
SD@CHC | OVER 7.5 | 54.5% | 4 | LOSS |
SD@CHC | CHC -111 | 54.8% | 4 | LOSS |
CIN@LAD | SHOHEI OHTANI OVER 1.5 BASES | 53.5% | 3 | WIN |
BOS@NYY | OVER 7 | 53.8% | 3 | LOSS |
CIN@LAD | ELLY DE LA CRUZ OVER 0.5 BASES | 54.4% | 4 | LOSS |
ARI@SD | SD -131 | 57.3% | 4 | WIN |
DET@BOS | BOS -115 | 56.4% | 5 | WIN |
NYM@CHC | NYM -110 | 54.1% | 3 | WIN |
HOU@ATH | ATH +118 | 50.8% | 4 | WIN |
NYM@CHC | OVER 7 | 54.5% | 3 | WIN |
STL@SF | OVER 7.5 | 55.9% | 5 | LOSS |
KC@LAA | TYLER TOLBERT UNDER 1.5 BASES | 54.4% | 4 | WIN |
MIL@SD | UNDER 9 | 54.7% | 4 | WIN |
MIA@PHI | KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS | 53.3% | 3 | WIN |
WAS@NYM | OVER 8.5 | 56.1% | 6 | LOSS |
LAA@COL | COL +108 | 50.5% | 3 | WIN |
TOR@KC | UNDER 9 | 54.7% | 4 | LOSS |
SEA@KC | KC +1.5 | 62.3% | 5 | LOSS |
NYY@MIN | OVER 9 | 55.1% | 4 | WIN |
MIA@COL | OVER 10.5 | 55.0% | 4 | WIN |
MIA@COL | AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS | 54.3% | 4 | WIN |
SEA@KC | BOBBY WITT UNDER 0.5 SINGLES | 54.4% | 4 | LOSS |
PHI@LAD | LAD -113 | 54.7% | 4 | LOSS |
NYY@BOS | OVER 7.5 | 54.3% | 3 | WIN |
KC@PHI | PHI -130 | 58.3% | 4 | WIN |
LAD@SF | OVER 7.5 | 54.7% | 4 | LOSS |
NYM@PHI | PHI -122 | 55.6% | 4 | WIN |
KC@CLE | KC -104 | 52.0% | 3 | WIN |
CIN@SD | JAKE CRONEWORTH OVER 0.5 HITS | 53.1% | 3 | WIN |
WAS@MIA | MIA -123 | 55.2% | 4 | LOSS |
LAA@KC | UNDER 9.5 | 54.9% | 3 | WIN |
TEX@ARI | UNDER 9 | 54.2% | 4 | WIN |
SF@COL | UNDER 11.5 | 56.4% | 6 | LOSS |
SF@COL | RAFAEL DEVERS OVER 1.5 BASES | 56.1% | 6 | WIN |
MIA@WAS | WAS -110 | 54.4% | 4 | WIN |
NYM@DET | OVER 8.5 | 54.5% | 4 | WIN |
TEX@ARI | UNDER 9.5 | 56.4% | 6 | WIN |
TEX@ARI | ALEJANDRO OSUNA UNDER 1.5 BASES | 54.1% | 4 | LOSS |
ATL@CHC | CHC -116 | 55.1% | 3 | WIN |
PHI@MIL | OVER 8.5 | 55.0% | 3 | WIN |
ARI@LAD | SHOHEI OHTANI OVER 2.5 BASES | 54.2% | 4 | WIN |
SEA@CLE | CLE +1.5 | 57.2% | 3 | WIN |
CHC@SF | CHC -105 | 54.1% | 4 | LOSS |
NYY@CHW | RYAN MCMAHON OVER 0.5 BASES | 54.1% | 4 | WIN |