Guardians vs Cubs Prediction — AI Finds CAN'T MISS MLB Lines & Props (Jul 03)
Updated: 2025-07-01T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The Cleveland Guardians and Chicago Cubs will face off in the final game of their three-game series at Wrigley Field on Thursday, July 3, 2025, with first pitch scheduled for 8:05 p.m. ET. Both teams are looking to gain momentum as they approach the All-Star break, with the Cubs aiming to solidify their position in the NL Central and the Guardians seeking to climb the AL Central standings.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Jul 03, 2025
Start Time: 8:05 PM EST
Venue: Wrigley Field
Cubs Record: (51-35)
Guardians Record: (40-44)
OPENING ODDS
CLE Moneyline: +132
CHC Moneyline: -157
CLE Spread: +1.5
CHC Spread: -1.5
Over/Under: 8.5
CLE
Betting Trends
- The Cleveland Guardians have a 56-55 record against the run line this season. In their last 10 games, they have covered the spread in 6 contests, indicating a slight positive trend.
CHC
Betting Trends
- The Chicago Cubs have a 30-35 record against the run line this season. At home, they have an 18-19 record against the spread, showing inconsistency in covering the spread at Wrigley Field.
MATCHUP TRENDS
- For Thursday’s game, the Cubs are favored on the moneyline at -158, with the Guardians at +133. The run line favors the Cubs at -1.5 with +132 odds, while the over/under for the game is set at 8.5 runs.
CLE vs. CHC
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: P. Crow-Armstrong over 6.5 Fantasy Score.
LIVE MLB ODDS
MLB ODDS COMPARISON
WANT MORE AI PICKS?
VS. SPREAD
325-240
NET UNITS
(INCL VIG)
+395.4
NET PROFIT
(INCL VIG)
$100/UNIT
$39,540
VS. SPREAD
1593-1364
NET UNITS
(INCL VIG)
+371.9
NET PROFIT
(INCL VIG)
$100/UNIT
$37,192
AI SPORTS PICK PRODUCTS
Create a Free Account

Remi Finds New Picks

Remi Works 24/7
Remi uses this probability to assign units to each pick.
Get Remi's AI Picks
Get Remi’s Top AI Sports Picks sent direct to your inbox.
Hedge Meaning in Betting | 4 Obvious Times to Hedge
Learn about hedge betting to manage risk and secure profits. Understand...
What is a Push in Betting? | 3 Ways To Use To Your Advantage
Understand what a push in betting means, how it happens in...
What Does the + and – Mean in Sports Betting? | 5 Easy Tips
Learn the basics of sports betting odds, what the plus (+)...
Cleveland vs Chicago Cubs Prediction & Odds:
Free MLB Betting Insights for 7/3/25
Ortiz, a right-hander with a 4-9 record and 4.36 ERA, has struggled to keep the ball in the park at times and must work more efficiently against a Cubs lineup that draws walks and drives the ball to all fields. Offensively, Cleveland is led by star third baseman José Ramírez, who has been excellent with a .305 batting average and .493 slugging percentage, and outfielder Steven Kwan, whose .296 average and .418 slugging make him one of the most reliable leadoff men in baseball. The Guardians will need more from veteran Carlos Santana, who’s hitting just .236, but still offers value as a switch-hitter with playoff experience. Defensively, the Guardians have been competent, and their bullpen has had its moments, but against a team like the Cubs that tends to capitalize on mistakes, execution must be nearly flawless. Oddsmakers have the Cubs favored on the moneyline at -158 and on the run line at -1.5 (+132), suggesting confidence in Horton and the home offense, though the over/under of 8.5 runs leaves room for offensive fireworks from both clubs. For Cleveland, a win would mean climbing above .500 again and injecting much-needed confidence into a talented but inconsistent squad. For Chicago, it’s about asserting dominance at home, keeping pace in the division, and heading into the break with their rotation stabilized and their offense humming. This game could go either way, but whichever team seizes early momentum on the mound will likely dictate the outcome in what should be a tightly contested, late-inning affair.
Tough.#GuardsBall pic.twitter.com/TONoGmWVhq
— Cleveland Guardians (@CleGuardians) July 3, 2025
Cleveland Guardians MLB Preview
The Cleveland Guardians enter Thursday’s series finale at Wrigley Field against the Chicago Cubs with a 37-37 record and an urgent desire to build consistency as they hover on the fringe of the AL Central race. Their season has been defined by streaks—modest win runs followed by frustrating stretches of offensive stagnation or starting pitching lapses—but with a win in this matchup, the Guardians would head into the All-Star break with renewed belief and a winning record. Leading the way for Cleveland is All-Star third baseman José Ramírez, who continues to be the heart and soul of the club, hitting .305 with a .493 slugging percentage and providing both timely power and elite defensive play at the hot corner. He’s been backed by the always-steady Steven Kwan, who is batting .296 and slugging .418 as the table-setter in the lineup, and by the veteran presence of Carlos Santana, whose .236 average doesn’t stand out but whose switch-hitting capabilities and playoff poise still bring intangible value to a youthful roster. The Guardians will turn to right-hander Luis Ortiz on the mound, a pitcher with tantalizing stuff but results that have yet to match his potential. Ortiz enters the game with a 4-9 record and a 4.36 ERA, and the Guardians need him to deliver a quality start against a Cubs team that has mashed right-handed pitching throughout the season.
Ortiz’s success typically hinges on fastball command and limiting walks; when he’s ahead in the count, he’s been able to induce groundballs and avoid damage, but trouble arises when his pitch count climbs early and he’s forced into the middle of the zone. Cleveland’s bullpen has been heavily utilized this season, and while it features a few dependable arms in high-leverage situations, it’s been an uneven group overall, requiring starting pitchers to go deeper into games to avoid exposure. Offensively, the Guardians have produced enough to remain competitive, but they often rely too heavily on Ramírez and Kwan for scoring, and they’ll need players like Josh Naylor or Gabriel Arias to come through in big spots to keep pace with the Cubs. Defensively, Cleveland has been solid, particularly in the infield where Andrés Giménez and Ramírez form a strong left side. The Guardians have covered the spread in six of their last 10 games, showing a trend of outperforming market expectations even in tight contests, and they come in as underdogs on Thursday despite having the offensive talent and veteran leadership to make this series finale winnable. If Ortiz can neutralize the top half of Chicago’s order and Ramírez gets the support he needs from the rest of the lineup, Cleveland could exit Wrigley with a key win and the momentum they’ve been chasing for much of the summer. For a team teetering on the edge of relevance in the postseason picture, every game is beginning to carry greater weight, and the Guardians know this is one of those moments that can shift the tone for the rest of their season.

Credit: USA TODAY/IMAGN
Chicago Cubs Cubs MLB Preview
The Chicago Cubs will close out their three-game series against the Cleveland Guardians on Thursday, July 3, with the confidence of a team playing strong baseball at home and sitting comfortably in playoff position with a 46-32 record. Wrigley Field has been kind to the Cubs this season, as they’ve gone 24-13 in front of their home crowd, and they’ve shown a reliable ability to win when favored, covering the moneyline in over 68% of those games. The team’s offensive identity has been shaped by a combination of discipline, power, and depth, with Kyle Tucker leading the charge with a .290 batting average and .533 slugging percentage. Tucker’s blend of consistency and power has made him one of the most impactful midseason additions in baseball, and he’s received strong support from Seiya Suzuki, who has quietly put together a standout season with a .258 average and .546 slugging percentage. Michael Busch has also emerged as an important piece, hitting .282 with a .517 SLG while providing versatility in the lineup. The Cubs’ offense doesn’t rely on a single superstar but rather a collective that works counts, puts the ball in play, and produces timely extra-base hits, especially in late innings.
On the mound, Chicago hands the ball to rising right-hander Cade Horton, who brings electric stuff and a promising profile as one of the franchise’s most exciting young arms. While still developing at the major league level, Horton has shown he can generate swings and misses with his fastball-slider combo and keep hitters off balance with occasional changes in pitch shape and sequencing. Against a Cleveland team that has been solid but not overwhelming offensively, Horton has a good opportunity to pitch deep into the game and potentially deliver one of his most efficient outings of the season. Chicago’s bullpen, anchored by experienced arms like Adbert Alzolay and Julian Merryweather, has been consistent and dependable when protecting late leads, something that has made the Cubs so tough to beat in close contests. Defensively, the Cubs continue to play clean baseball, ranking well in defensive runs saved and excelling at turning double plays, particularly up the middle with Nico Hoerner and Dansby Swanson. They’ve held opponents to low run totals at home and typically find ways to manufacture just enough offense to support their arms. Coming into this game as -158 moneyline favorites and -1.5 run line favorites with a game total of 8.5, oddsmakers clearly believe in the Cubs’ combination of pitching advantage, home dominance, and offensive consistency. A series win over Cleveland would further strengthen their NL Central standing and provide momentum heading into the All-Star break, and if Horton gives them five solid innings while the middle of the order capitalizes on run-scoring opportunities, Chicago could be in for another textbook Wrigley Field win. This is a team playing with quiet confidence, executing in all phases of the game, and sending a message that they intend to be major players in the National League postseason picture.
music to our ears. ☺️ pic.twitter.com/YzQPdlRiff
— Chicago Cubs (@Cubs) July 3, 2025
Cleveland vs. Chicago Cubs Prop Picks (AI)
Cleveland vs. Chicago Cubs Prediction (AI)

Remi, our AI sports algorithm, has been pouring over millions of data from every past game between the Guardians and Cubs and using recursive machine learning and industry leading AI to boil down the data to a single cover probability.
The Algorithm has been most fixated on the linear correlation of factor human bettors often put on coaching factors between a Guardians team going up against a possibly improved Cubs team. We’ve found the true game analytics appear to reflect a slight lean against one Vegas line specifically.
Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.
Below is our current AI Cleveland vs Chicago Cubs picks, computer picks Guardians vs Cubs, best bets, model edges, confidence ratings.
![]() |
DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
---|---|---|---|---|---|---|
MLB | 10/20 | SEA@TOR | UNLOCK THIS PICK | 2 |
![]() |
|
MLB | 10/20 | SEA@TOR | UNLOCK THIS PICK | 0 |
![]() |
These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.
Guardians Betting Trends
The Cleveland Guardians have a 56-55 record against the run line this season. In their last 10 games, they have covered the spread in 6 contests, indicating a slight positive trend.
Cubs Betting Trends
The Chicago Cubs have a 30-35 record against the run line this season. At home, they have an 18-19 record against the spread, showing inconsistency in covering the spread at Wrigley Field.
Guardians vs. Cubs Matchup Trends
For Thursday’s game, the Cubs are favored on the moneyline at -158, with the Guardians at +133. The run line favors the Cubs at -1.5 with +132 odds, while the over/under for the game is set at 8.5 runs.
Cleveland vs. Chicago Cubs Game Info
What time does Cleveland vs Chicago Cubs start on July 03, 2025?
Cleveland vs Chicago Cubs starts on July 03, 2025 at 8:05 PM EST.
Where is Cleveland vs Chicago Cubs being played?
Venue: Wrigley Field.
What are the opening odds for Cleveland vs Chicago Cubs?
Spread: Chicago Cubs -1.5
Moneyline: Cleveland +132, Chicago Cubs -157
Over/Under: 8.5
What are the records for Cleveland vs Chicago Cubs?
Cleveland: (40-44) | Chicago Cubs: (51-35)
What is the AI best bet for Cleveland vs Chicago Cubs?
Remi's searched hard and found the best prop for this matchup: P. Crow-Armstrong over 6.5 Fantasy Score.. Prices move—always shop for the best number.
What are Cleveland vs Chicago Cubs trending bets?
For Thursday’s game, the Cubs are favored on the moneyline at -158, with the Guardians at +133. The run line favors the Cubs at -1.5 with +132 odds, while the over/under for the game is set at 8.5 runs.
What are Cleveland trending bets?
CLE trend: The Cleveland Guardians have a 56-55 record against the run line this season. In their last 10 games, they have covered the spread in 6 contests, indicating a slight positive trend.
What are Chicago Cubs trending bets?
CHC trend: The Chicago Cubs have a 30-35 record against the run line this season. At home, they have an 18-19 record against the spread, showing inconsistency in covering the spread at Wrigley Field.
Where can I find AI Picks for Cleveland vs Chicago Cubs?
See our latest MLB picks and odds pages for 2025 to compare prices before you bet.
Cleveland vs. Chicago Cubs Odds
AI algorithm Remi is pouring through tons of data points on each player. In fact, anytime the Cleveland vs Chicago Cubs trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme travel distance rarely follow normal, predictable betting trends.
Cleveland vs Chicago Cubs Opening Odds
CLE Moneyline:
+132 CHC Moneyline: -157
CLE Spread: +1.5
CHC Spread: -1.5
Over/Under: 8.5
Cleveland vs Chicago Cubs Live Odds
Games | PTS | ML | SPR | O/U | |
---|---|---|---|---|---|
Oct 24, 2025 9:08PM EDT
Los Angeles Dodgers
Toronto Blue Jays
10/24/25 9:08PM
Dodgers
Blue Jays
|
–
–
|
-140
+127
|
-1.5 (+124)
+1.5 (-140)
|
O 7.5 (+107)
U 7.5 (-123)
|
MLB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Cleveland Guardians vs. Chicago Cubs Cubs on July 03, 2025 at Wrigley Field.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.
![]() |
LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
TOR@SEA | OVER 7 | 54.9% | 3 | WIN |
LAD@MIL | UNDER 7.5 | 56.6% | 6 | WIN |
TOR@NYY | OVER 8 | 54.9% | 4 | WIN |
TOR@NYY | CARLOS RODON OVER 1.5 TOTAL WALKS ALLOWED | 53.3% | 3 | WIN |
NYY@TOR | OVER 7.5 | 54.8% | 2 | WIN |
LAD@PHI | OVER 7 | 53.8% | 3 | WIN |
SD@CHC | CHC -109 | 53.8% | 3 | WIN |
SD@CHC | OVER 7.5 | 54.5% | 4 | LOSS |
SD@CHC | CHC -111 | 54.8% | 4 | LOSS |
CIN@LAD | SHOHEI OHTANI OVER 1.5 BASES | 53.5% | 3 | WIN |
BOS@NYY | OVER 7 | 53.8% | 3 | LOSS |
CIN@LAD | ELLY DE LA CRUZ OVER 0.5 BASES | 54.4% | 4 | LOSS |
ARI@SD | SD -131 | 57.3% | 4 | WIN |
DET@BOS | BOS -115 | 56.4% | 5 | WIN |
NYM@CHC | NYM -110 | 54.1% | 3 | WIN |
HOU@ATH | ATH +118 | 50.8% | 4 | WIN |
NYM@CHC | OVER 7 | 54.5% | 3 | WIN |
STL@SF | OVER 7.5 | 55.9% | 5 | LOSS |
KC@LAA | TYLER TOLBERT UNDER 1.5 BASES | 54.4% | 4 | WIN |
MIL@SD | UNDER 9 | 54.7% | 4 | WIN |
MIA@PHI | KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS | 53.3% | 3 | WIN |
WAS@NYM | OVER 8.5 | 56.1% | 6 | LOSS |
LAA@COL | COL +108 | 50.5% | 3 | WIN |
TOR@KC | UNDER 9 | 54.7% | 4 | LOSS |
SEA@KC | KC +1.5 | 62.3% | 5 | LOSS |
NYY@MIN | OVER 9 | 55.1% | 4 | WIN |
MIA@COL | OVER 10.5 | 55.0% | 4 | WIN |
MIA@COL | AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS | 54.3% | 4 | WIN |
SEA@KC | BOBBY WITT UNDER 0.5 SINGLES | 54.4% | 4 | LOSS |
PHI@LAD | LAD -113 | 54.7% | 4 | LOSS |
NYY@BOS | OVER 7.5 | 54.3% | 3 | WIN |
KC@PHI | PHI -130 | 58.3% | 4 | WIN |
LAD@SF | OVER 7.5 | 54.7% | 4 | LOSS |
NYM@PHI | PHI -122 | 55.6% | 4 | WIN |
KC@CLE | KC -104 | 52.0% | 3 | WIN |
CIN@SD | JAKE CRONEWORTH OVER 0.5 HITS | 53.1% | 3 | WIN |
WAS@MIA | MIA -123 | 55.2% | 4 | LOSS |
LAA@KC | UNDER 9.5 | 54.9% | 3 | WIN |
TEX@ARI | UNDER 9 | 54.2% | 4 | WIN |
SF@COL | UNDER 11.5 | 56.4% | 6 | LOSS |
SF@COL | RAFAEL DEVERS OVER 1.5 BASES | 56.1% | 6 | WIN |
MIA@WAS | WAS -110 | 54.4% | 4 | WIN |
NYM@DET | OVER 8.5 | 54.5% | 4 | WIN |
TEX@ARI | UNDER 9.5 | 56.4% | 6 | WIN |
TEX@ARI | ALEJANDRO OSUNA UNDER 1.5 BASES | 54.1% | 4 | LOSS |
ATL@CHC | CHC -116 | 55.1% | 3 | WIN |
PHI@MIL | OVER 8.5 | 55.0% | 3 | WIN |
ARI@LAD | SHOHEI OHTANI OVER 2.5 BASES | 54.2% | 4 | WIN |
SEA@CLE | CLE +1.5 | 57.2% | 3 | WIN |
CHC@SF | CHC -105 | 54.1% | 4 | LOSS |
NYY@CHW | RYAN MCMAHON OVER 0.5 BASES | 54.1% | 4 | WIN |