Guardians vs. Cubs
Prediction, Odds & Props
Jul 02 | MLB AI Picks

Updated: 2025-06-30T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Chicago Cubs and Cleveland Guardians face off on Wednesday, July 2, 2025, at Wrigley Field in the second game of their interleague series. The Cubs, leading the NL Central, aim to capitalize on their home-field advantage, while the Guardians look to rebound from recent struggles and stay competitive in the AL Wild Card race.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Jul 02, 2025

Start Time: 8:05 PM EST​

Venue: Wrigley Field​

Cubs Record: (50-35)

Guardians Record: (40-43)

OPENING ODDS

CLE Moneyline: +134

CHC Moneyline: -159

CLE Spread: +1.5

CHC Spread: -1.5

Over/Under: 9

CLE
Betting Trends

  • The Guardians have struggled against the spread recently, covering in only 2 of their last 7 games.

CHC
Betting Trends

  • The Cubs have a 35-34 record against the run line this season, indicating a near-even performance in covering spreads.

MATCHUP TRENDS

  • Historically, the Guardians hold a slight edge over the Cubs with a 23-20 overall record, including a current five-game winning streak against Chicago.

CLE vs. CHC
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: M. Shaw over 3 Fantasy Score.

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Cleveland vs Chicago Cubs Prediction & Odds:
Free MLB Betting Insights for 7/2/25

The Wednesday, July 2, 2025, interleague showdown between the Cleveland Guardians and Chicago Cubs at Wrigley Field features two teams heading in different directions as the season progresses, with the Cubs leading the NL Central and the Guardians continuing to fight for relevance in the AL Wild Card picture. The Cubs, with a strong 25–13 home record, are favored behind the reliable left arm of Matthew Boyd, who enters the game with a 7–3 record and an impressive 2.65 ERA, anchoring a pitching staff that has been one of the club’s key strengths this year. Boyd’s ability to limit hard contact and work deep into games has eased the burden on the bullpen, which has also performed well when called upon in close games. Offensively, the Cubs have enjoyed contributions from several key bats, most notably Michael Busch and Seiya Suzuki, who continue to spark rallies and provide both power and consistency. Cody Bellinger, while not quite replicating his 2023 numbers, still adds valuable experience and run-producing potential in the middle of the lineup. On the opposite side, the Guardians are expected to counter with right-hander Tanner Bibee, who carries a 4–8 record with a 3.90 ERA and has shown flashes of dominance but often suffers from lack of run support.

That’s been a recurring issue for the Guardians, whose offensive output has leaned almost entirely on the consistent bat of José Ramírez, who leads the team with a .317 average and 13 home runs, but hasn’t had much help from the rest of the lineup. While Cleveland has a decent bullpen, its usage has been erratic, and defensive lapses have made it difficult to protect tight leads or stay close in low-scoring games. Historically, the Guardians have had a slight edge in this matchup, with a 23–20 overall record against the Cubs and a five-game win streak in head-to-head play, but Chicago’s current form and home dominance paint a different picture. The Cubs have hovered near even ATS this year, while the Guardians have covered the spread in only two of their last seven games, suggesting a downward trend that may be tough to reverse against a team that’s firing on all cylinders at home. To have a shot at pulling off the upset, Cleveland will need a sharp outing from Bibee, clutch hitting from Ramírez and some unlikely offensive contributors to rise to the occasion. For the Cubs, the formula is clearer: get Boyd into the sixth or seventh inning with a lead, keep pressure on Bibee early, and trust their bullpen to close the door. With the All-Star break approaching, this game holds added significance for both clubs—Chicago is looking to solidify its status atop the NL Central, while Cleveland is desperate to string together wins and avoid falling too far behind in the playoff hunt. The matchup favors the Cubs, but interleague play has a history of delivering surprises, and the Guardians will be hoping this is one of them.

Cleveland Guardians MLB Preview

The Cleveland Guardians head into their July 2 matchup against the Chicago Cubs at Wrigley Field with a 36–47 record, looking to halt a disappointing slide and find momentum before the All-Star break. While they’ve historically performed well against the Cubs, winning five straight head-to-head meetings and holding a slight 23–20 all-time advantage, this version of the Guardians has struggled to replicate past success, particularly when it comes to offensive production and late-inning execution. Their lineup continues to revolve almost entirely around José Ramírez, who has been exceptional again in 2025, slashing .317 with 13 home runs and a team-best OPS, but the lack of consistent run support from the rest of the batting order has left Cleveland vulnerable in close games. The middle and bottom of the lineup has struggled to generate extra-base hits or sustain rallies, placing even more pressure on Ramírez to carry the offense. Tanner Bibee will take the mound for the Guardians, bringing a 4–8 record and 3.90 ERA into the contest; while he’s shown strong command and occasional flashes of brilliance, his outing results often reflect the lack of support from both the lineup and bullpen behind him. Bibee’s biggest challenge will be managing Chicago’s power threats, particularly in the early innings, and avoiding the high pitch counts that have plagued some of his starts.

The Guardians bullpen has been inconsistent, struggling with control issues and an inability to strand inherited runners, which has cost them several late leads throughout the season. Defensively, Cleveland has been sloppy at times, with fielding miscues leading to unearned runs in tight contests, and they’ll need a clean game to compete against a fundamentally sound Cubs team that rarely beats itself. In terms of betting trends, Cleveland has been cold against the spread, covering in just two of their last seven games, reflecting their broader struggles to stay competitive in games against stronger opponents. Their road record has also left much to be desired, and Wrigley Field, particularly in a day game scenario with shifting winds, can be a tough environment for visiting pitchers unfamiliar with the conditions. Manager Stephen Vogt has tried juggling the lineup and bullpen roles in search of a spark, but the lack of depth and production outside of Ramírez continues to haunt this roster. If the Guardians are going to have a chance at pulling off an upset on Wednesday, it will require a quality start from Bibee, timely hitting from supporting players like Josh Naylor or Andrés Giménez, and a rare error-free performance from the defense and bullpen. As it stands, the Guardians are in desperate need of a statement win, and taking one on the road against the NL Central-leading Cubs would go a long way in restoring belief in a team that has shown only fleeting glimpses of the potential many expected to see this season.

The Chicago Cubs and Cleveland Guardians face off on Wednesday, July 2, 2025, at Wrigley Field in the second game of their interleague series. The Cubs, leading the NL Central, aim to capitalize on their home-field advantage, while the Guardians look to rebound from recent struggles and stay competitive in the AL Wild Card race. Cleveland vs Chicago Cubs AI Prediction: Free MLB Betting Insights for Jul 02. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Chicago Cubs Cubs MLB Preview

The Chicago Cubs enter their July 2 matchup against the Cleveland Guardians at Wrigley Field with confidence and purpose as they look to extend their dominance at home and further cement their position atop the NL Central. With a 25–13 home record and a recent stretch of solid baseball, the Cubs have found success through a balance of reliable starting pitching, timely hitting, and a bullpen that has shown the ability to close out games under pressure. Matthew Boyd is slated to start for Chicago, and the veteran left-hander has delivered consistently all season long, boasting a 7–3 record with a 2.65 ERA, emerging as a stabilizing presence in the rotation and giving the Cubs quality innings every fifth day. Boyd’s experience and ability to command the strike zone early in counts will be vital against a Guardians lineup that leans heavily on José Ramírez for offense. Offensively, the Cubs have been energized by the production of Seiya Suzuki and Michael Busch, both of whom have delivered key hits in high-leverage spots and combined to form the heart of a lineup capable of grinding down opposing pitchers. Suzuki, in particular, has seen his power numbers rise while maintaining a solid average, while Busch provides left-handed thump and on-base skills that have helped lengthen the order.

Though Cody Bellinger hasn’t replicated his 2023 MVP-level numbers, he remains a valuable run producer and clubhouse presence, while young players like Nico Hoerner and Pete Crow-Armstrong have contributed with speed and defense. The Cubs bullpen has been another strength, with closer Adbert Alzolay and setup man Mark Leiter Jr. anchoring the late innings and ensuring that most leads heading into the eighth inning remain secure. Defensively, Chicago has been crisp and efficient, committing few errors and regularly converting routine plays, which has further supported the pitching staff’s ability to attack the strike zone confidently. Manager Craig Counsell has managed the roster with precision, blending analytics and instinct to push the right buttons in terms of matchups, bullpen management, and lineup construction, particularly in interleague games where versatility is often required. From a betting perspective, the Cubs are near even against the spread this season, but their dominance at home and stability in key areas of the game give them a clear edge in this contest. With the All-Star break approaching and division rivals pressing hard, the Cubs know the importance of banking wins against struggling teams like Cleveland. If Boyd delivers his usual six-plus innings of quality work, and the bats jump on Guardians starter Tanner Bibee early, Chicago should find itself in prime position to secure another win and continue building on what has quietly been one of the NL’s more consistent first-half performances. This game presents an opportunity not just to win a series but to demonstrate their ability to handle business against teams they are expected to beat—an essential trait for any club with postseason aspirations.

Cleveland vs. Chicago Cubs Prop Picks (AI)

Remi is pouring through loads of stats on each team. In fact, anytime the Guardians and Cubs play there’s always several intriguing observations to key in on. Not to mention games played at Wrigley Field in Jul rarely follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: M. Shaw over 3 Fantasy Score.

Cleveland vs. Chicago Cubs Prediction (AI)

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Remi, our AI sports genius, has been pouring over mountains of data from every angle between the Guardians and Cubs and using recursive machine learning and industry leading AI to analyze the data to a single cover probability.

Interestingly enough, the data has been most fixated on the linear correlation of factor knucklehead sportsbettors often put on Chicago Cubs’s strength factors between a Guardians team going up against a possibly healthy Cubs team. We’ve found the true game analytics appear to reflect a slight lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI Cleveland vs Chicago Cubs picks, computer picks Guardians vs Cubs, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
MLB 9/26 DET@BOS UNLOCK THIS PICK 5 EXECUTIVE Locked EXECUTIVE
MLB 9/26 BAL@NYY UNLOCK THIS PICK 4 INTEL Locked INTEL
MLB 9/26 ARI@SD UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
MLB 9/26 NYM@MIA UNLOCK THIS PICK 1 INTEL Locked INTEL
MLB 9/26 NYM@MIA GET FREE PICK NOW 1
MLB 9/26 COL@SF UNLOCK THIS PICK 0 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

Guardians Betting Trends

The Guardians have struggled against the spread recently, covering in only 2 of their last 7 games.

Cubs Betting Trends

The Cubs have a 35-34 record against the run line this season, indicating a near-even performance in covering spreads.

Guardians vs. Cubs Matchup Trends

Historically, the Guardians hold a slight edge over the Cubs with a 23-20 overall record, including a current five-game winning streak against Chicago.

Cleveland vs. Chicago Cubs Game Info

Cleveland vs Chicago Cubs starts on July 02, 2025 at 8:05 PM EST.

Spread: Chicago Cubs -1.5
Moneyline: Cleveland +134, Chicago Cubs -159
Over/Under: 9

Cleveland: (40-43)  |  Chicago Cubs: (50-35)

Remi's searched hard and found the best prop for this matchup: M. Shaw over 3 Fantasy Score.. Prices move—always shop for the best number.

Historically, the Guardians hold a slight edge over the Cubs with a 23-20 overall record, including a current five-game winning streak against Chicago.

CLE trend: The Guardians have struggled against the spread recently, covering in only 2 of their last 7 games.

CHC trend: The Cubs have a 35-34 record against the run line this season, indicating a near-even performance in covering spreads.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

Cleveland vs. Chicago Cubs Odds

Remi is pouring through mountains of data points on each player. In fact, anytime the Cleveland vs Chicago Cubs trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme hostile environments can often follow normal, predictable betting trends.

Cleveland vs Chicago Cubs Opening Odds

CLE Moneyline: +134
CHC Moneyline: -159
CLE Spread: +1.5
CHC Spread: -1.5
Over/Under: 9

Cleveland vs Chicago Cubs Live Odds

Games PTS ML SPR O/U
Sep 27, 2025 1:06PM EDT
Baltimore Orioles
New York Yankees
9/27/25 1:06PM
Orioles
Yankees
+194
-235
+1.5 (-105)
-1.5 (-114)
O 8.5 (-122)
U 8.5 (+100)
Sep 27, 2025 2:21PM EDT
St Louis Cardinals
Chicago Cubs
9/27/25 2:21PM
Cardinals
Cubs
 
-168
 
-1.5 (+118)
O 9 (-122)
U 9 (+100)
Sep 27, 2025 3:09PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/27/25 3:09PM
Rays
Blue Jays
+132
-156
+1.5 (-154)
-1.5 (+128)
O 8.5 (-106)
U 8.5 (-114)
Sep 27, 2025 4:06PM EDT
Chicago White Sox
Washington Nationals
9/27/25 4:06PM
White Sox
Nationals
+102
-120
-1.5 (+162)
+1.5 (-196)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 4:06PM EDT
Colorado Rockies
San Francisco Giants
9/27/25 4:06PM
Rockies
Giants
+198
-240
+1.5 (-110)
-1.5 (-110)
O 8 (-108)
U 8 (-112)
Sep 27, 2025 4:11PM EDT
New York Mets
Miami Marlins
9/27/25 4:11PM
Mets
Marlins
-124
+106
-1.5 (+130)
+1.5 (-156)
O 8.5 (-112)
U 8.5 (-108)
Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
+177
-197
+1.5 (-118)
-1.5 (-102)
O 8.5 (-118)
U 8.5 (-102)
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
+128
-152
+1.5 (-178)
-1.5 (+146)
O 7.5 (-120)
U 7.5 (-102)
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
+143
-158
+1.5 (-150)
-1.5 (+130)
O 8.5 (+100)
U 8.5 (-120)
Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
+132
-156
+1.5 (-172)
-1.5 (+142)
O 7 (-120)
U 7 (-102)
Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
+120
-132
+1.5 (-180)
-1.5 (+157)
O 7.5 (-115)
U 7.5 (-105)
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
+102
-120
+1.5 (-215)
-1.5 (+180)
O 7.5 (-110)
U 7.5 (-110)
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
+104
-115
+1.5 (-185)
-1.5 (+161)
O 10 (-110)
U 10 (-110)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Cleveland Guardians vs. Chicago Cubs Cubs on July 02, 2025 at Wrigley Field.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS
CIN@ARI KEBRYAN HAYES STRIKEOUTS UNDER 0.5 56.2% 6 WIN
LAD@SD SD +110 50.9% 6 WIN