Cardinals vs Pirates Prediction — AI Finds CAN'T MISS MLB Lines & Props (Jul 01)
Updated: 2025-06-29T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The St. Louis Cardinals and Pittsburgh Pirates continue their National League Central rivalry on Tuesday, July 1, 2025, at PNC Park in Pittsburgh, with first pitch scheduled for 6:40 p.m. ET. Both teams are looking to gain ground in the division standings, making this matchup crucial for their playoff aspirations.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Jul 01, 2025
Start Time: 6:40 PM EST
Venue: PNC Park
Pirates Record: (36-50)
Cardinals Record: (47-39)
OPENING ODDS
STL Moneyline: +140
PIT Moneyline: -167
STL Spread: +1.5
PIT Spread: -1.5
Over/Under: 7
STL
Betting Trends
- The St. Louis Cardinals have a 5-5 record against the spread (ATS) in their last 10 games, indicating a balanced performance in recent matchups.
PIT
Betting Trends
- The Pittsburgh Pirates are 3-2 against the run line in their last 5 games, showcasing a slight edge in covering the spread recently.
MATCHUP TRENDS
- In their last 10 games, the Pirates have a 7-3 record against the spread, indicating strong recent performance in covering the run line.
STL vs. PIT
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: A. McCutchen over 5 Fantasy Score.
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St. Louis vs Pittsburgh Prediction & Odds:
Free MLB Betting Insights for 7/1/25
Offensively, it’s been a struggle, as the lineup features low batting averages from several starters, including Oneil Cruz (.210) and Bryan Reynolds (.239), but both possess game-changing tools that can spark rallies if they find their rhythm. The Pirates have been covering the run line well lately, going 7-3 ATS over their last 10 games, which signals improved competitiveness even when not winning outright. Pittsburgh’s defense remains spotty and their bullpen depth is thin, making it difficult to close out close games consistently. On the other hand, the Cardinals are relatively balanced, with their defense, bullpen, and lineup all capable of doing enough to support their starters. The keys to this game will likely come down to run prevention and execution—whether Gray can quiet the Pirates’ power threats, and whether Skenes can neutralize St. Louis’ experienced lineup through the middle innings. If Skenes is sharp and avoids the big inning, Pittsburgh could keep this tight and possibly steal a win late. However, St. Louis has more to lose and will be motivated to take care of business against a divisional opponent they’ve historically handled well. This game could turn into a pitcher’s duel early, and the outcome may rest on which bullpen holds up better and which lineup capitalizes on limited scoring opportunities. With playoff implications already looming for the Cardinals and the Pirates eager to play spoiler while developing their young core, fans can expect a tense, strategic contest under the lights in Pittsburgh.
First of three in Pittsburgh pic.twitter.com/GKGfTYVlUQ
— St. Louis Cardinals (@Cardinals) June 30, 2025
St. Louis Cardinals MLB Preview
The St. Louis Cardinals head into Tuesday’s divisional matchup against the Pittsburgh Pirates with a 47-39 record and their eyes set firmly on postseason positioning as they continue to claw their way up the NL Central standings. This season has been defined by resilience and veteran consistency for St. Louis, with a balanced roster that has managed to win key series and maintain pace with the Brewers and Reds despite dealing with patches of offensive inconsistency. Leading the rotation is veteran right-hander Sonny Gray, who has delivered ace-level performance in his first year in a Cardinals uniform, owning an 8-2 record and 3.36 ERA while anchoring a staff that has needed his steadiness amid a mix of young and unproven arms. Gray’s ability to command the strike zone and limit damage has helped the team win several low-scoring affairs, which has been crucial given that St. Louis ranks middle of the pack in runs scored. Offensively, Brendan Donovan has emerged as a catalyst at the top of the order, batting .297 and delivering quality at-bats nearly every night, while Nolan Arenado remains a reliable presence in the middle of the lineup, contributing with power, leadership, and clutch hits even if his overall numbers are slightly below his All-Star peaks.
Willson Contreras, who adds thunder from the catcher position, continues to be one of the team’s key run producers, and young contributors like Masyn Winn have added speed and energy to a lineup that can grind out innings even when not slugging. Defensively, the Cardinals remain one of the sharper units in the league, rarely giving opponents extra outs and often helping their pitchers navigate out of jams with timely double plays and solid outfield positioning. Their bullpen, though not overpowering, has found stability in the back end, especially in the hands of closer Ryan Helsley, who has quietly put together a strong season and has been dependable in late-game situations. On the betting front, St. Louis has gone 5-5 against the spread over their last 10 games, reflecting their steady but unspectacular play, yet their ability to win close games and manufacture runs late gives them an edge in matchups like this one against rebuilding teams. The Cardinals will approach this game as a must-win against a divisional opponent they’ve historically fared well against, and with Gray on the mound and a veteran core in place, they’ll aim to take advantage of a Pirates team that has struggled to score consistently. A win here not only helps them in the standings but also sends a message that St. Louis intends to be a serious factor in the National League playoff race, armed with experienced players, high baseball IQ, and a sense of urgency as July begins.

Credit: USA TODAY/IMAGN
Pittsburgh Pirates MLB Preview
The Pittsburgh Pirates enter Tuesday’s NL Central matchup against the St. Louis Cardinals with a 36-50 record, sitting well outside of playoff contention but still playing with purpose as they focus on developing their young talent and finding consistency in the second half of the season. Despite their struggles in the win column, the Pirates have shown encouraging signs of growth, especially in recent games where they’ve gone 7-3 against the spread, often covering as underdogs thanks to improved starting pitching and competitive play in close contests. One of the brightest spots of the season has been rookie phenom Paul Skenes, who takes the mound with a sparkling 2.12 ERA over 106 innings, quickly emerging as the staff ace and a foundational piece for the team’s future. His dominant fastball-slider combination and fearlessness in attacking hitters have given Pittsburgh a chance to win every fifth day, and the team has responded well behind him, even if the run support hasn’t always been there. Offensively, the Pirates continue to search for consistent production, with former top prospect Oneil Cruz struggling to a .210 average but still flashing elite tools that can change a game in a moment, and Bryan Reynolds providing a steadier presence despite a modest .239 average.
Andrew McCutchen, the veteran heart of the team, remains a key influence both at the plate and in the clubhouse, offering leadership and a calming presence for younger players. While the offense remains a work in progress, with issues in on-base percentage and situational hitting, Pittsburgh has shown a knack for hanging around in games and capitalizing when opponents slip, especially at home. Defensively, the Pirates have improved in the infield but still suffer from occasional lapses that lead to extended innings, and the bullpen has been inconsistent, forcing Skenes and other starters to work deeper into games than ideal. Still, manager Derek Shelton has kept the team focused and competitive, and there’s a growing belief that this young core, if supported by continued development and eventual reinforcements, could form the nucleus of a contending team in the next few seasons. For now, the Pirates see games like this as an opportunity to test themselves against division rivals and establish a more assertive identity, particularly when their ace is on the mound. A strong outing from Skenes, coupled with timely hits from Reynolds, Cruz, or Ke’Bryan Hayes, could be enough to pull off a statement win at home and add to their recent momentum against the spread. While the postseason may be out of reach this year, the Pirates have plenty to play for, and each game against a team like St. Louis presents a chance to build confidence, develop chemistry, and show their fans that a new era of competitive baseball might not be far off.
Steel City shutout. #RaiseIt pic.twitter.com/A9Ya9yckiJ
— Pittsburgh Pirates (@Pirates) July 1, 2025
St. Louis vs. Pittsburgh Prop Picks (AI)
St. Louis vs. Pittsburgh Prediction (AI)

Remi, our AI sports wizard, has been pouring over millions of data from every angle between the Cardinals and Pirates and using recursive machine learning and industry leading AI to analyze the data to a single cover probability.
Oddly enough, we’ve seen the AI has been most keyed in on the unproportionally assigned factor knucklehead sportsbettors often put on Pittsburgh’s strength factors between a Cardinals team going up against a possibly rested Pirates team. Trends look to say the true game analytics might reflect a strong lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.
Below is our current AI St. Louis vs Pittsburgh picks, computer picks Cardinals vs Pirates, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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MLB | 10/20 | SEA@TOR | UNLOCK THIS PICK | 2 |
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MLB | 10/20 | SEA@TOR | UNLOCK THIS PICK | 0 |
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.
Cardinals Betting Trends
The St. Louis Cardinals have a 5-5 record against the spread (ATS) in their last 10 games, indicating a balanced performance in recent matchups.
Pirates Betting Trends
The Pittsburgh Pirates are 3-2 against the run line in their last 5 games, showcasing a slight edge in covering the spread recently.
Cardinals vs. Pirates Matchup Trends
In their last 10 games, the Pirates have a 7-3 record against the spread, indicating strong recent performance in covering the run line.
St. Louis vs. Pittsburgh Game Info
What time does St. Louis vs Pittsburgh start on July 01, 2025?
St. Louis vs Pittsburgh starts on July 01, 2025 at 6:40 PM EST.
Where is St. Louis vs Pittsburgh being played?
Venue: PNC Park.
What are the opening odds for St. Louis vs Pittsburgh?
Spread: Pittsburgh -1.5
Moneyline: St. Louis +140, Pittsburgh -167
Over/Under: 7
What are the records for St. Louis vs Pittsburgh?
St. Louis: (47-39) | Pittsburgh: (36-50)
What is the AI best bet for St. Louis vs Pittsburgh?
Remi's searched hard and found the best prop for this matchup: A. McCutchen over 5 Fantasy Score.. Prices move—always shop for the best number.
What are St. Louis vs Pittsburgh trending bets?
In their last 10 games, the Pirates have a 7-3 record against the spread, indicating strong recent performance in covering the run line.
What are St. Louis trending bets?
STL trend: The St. Louis Cardinals have a 5-5 record against the spread (ATS) in their last 10 games, indicating a balanced performance in recent matchups.
What are Pittsburgh trending bets?
PIT trend: The Pittsburgh Pirates are 3-2 against the run line in their last 5 games, showcasing a slight edge in covering the spread recently.
Where can I find AI Picks for St. Louis vs Pittsburgh?
See our latest MLB picks and odds pages for 2025 to compare prices before you bet.
St. Louis vs. Pittsburgh Odds
AI algorithm Remi is pouring through loads of data points on each team. In fact, anytime the St. Louis vs Pittsburgh trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme travel distance can often follow normal, predictable betting trends.
St. Louis vs Pittsburgh Opening Odds
STL Moneyline:
+140 PIT Moneyline: -167
STL Spread: +1.5
PIT Spread: -1.5
Over/Under: 7
St. Louis vs Pittsburgh Live Odds
Games | PTS | ML | SPR | O/U | |
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Oct 24, 2025 8:00PM EDT
Los Angeles Dodgers
Toronto Blue Jays
10/24/25 8PM
Dodgers
Blue Jays
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–
–
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-157
+129
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-1.5 (+118)
+1.5 (-144)
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O 7.5 (+102)
U 7.5 (-125)
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MLB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers St. Louis Cardinals vs. Pittsburgh Pirates on July 01, 2025 at PNC Park.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
TOR@SEA | OVER 7 | 54.9% | 3 | WIN |
LAD@MIL | UNDER 7.5 | 56.6% | 6 | WIN |
TOR@NYY | OVER 8 | 54.9% | 4 | WIN |
TOR@NYY | CARLOS RODON OVER 1.5 TOTAL WALKS ALLOWED | 53.3% | 3 | WIN |
NYY@TOR | OVER 7.5 | 54.8% | 2 | WIN |
LAD@PHI | OVER 7 | 53.8% | 3 | WIN |
SD@CHC | CHC -109 | 53.8% | 3 | WIN |
SD@CHC | OVER 7.5 | 54.5% | 4 | LOSS |
SD@CHC | CHC -111 | 54.8% | 4 | LOSS |
CIN@LAD | SHOHEI OHTANI OVER 1.5 BASES | 53.5% | 3 | WIN |
BOS@NYY | OVER 7 | 53.8% | 3 | LOSS |
CIN@LAD | ELLY DE LA CRUZ OVER 0.5 BASES | 54.4% | 4 | LOSS |
ARI@SD | SD -131 | 57.3% | 4 | WIN |
DET@BOS | BOS -115 | 56.4% | 5 | WIN |
NYM@CHC | NYM -110 | 54.1% | 3 | WIN |
HOU@ATH | ATH +118 | 50.8% | 4 | WIN |
NYM@CHC | OVER 7 | 54.5% | 3 | WIN |
STL@SF | OVER 7.5 | 55.9% | 5 | LOSS |
KC@LAA | TYLER TOLBERT UNDER 1.5 BASES | 54.4% | 4 | WIN |
MIL@SD | UNDER 9 | 54.7% | 4 | WIN |
MIA@PHI | KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS | 53.3% | 3 | WIN |
WAS@NYM | OVER 8.5 | 56.1% | 6 | LOSS |
LAA@COL | COL +108 | 50.5% | 3 | WIN |
TOR@KC | UNDER 9 | 54.7% | 4 | LOSS |
SEA@KC | KC +1.5 | 62.3% | 5 | LOSS |
NYY@MIN | OVER 9 | 55.1% | 4 | WIN |
MIA@COL | OVER 10.5 | 55.0% | 4 | WIN |
MIA@COL | AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS | 54.3% | 4 | WIN |
SEA@KC | BOBBY WITT UNDER 0.5 SINGLES | 54.4% | 4 | LOSS |
PHI@LAD | LAD -113 | 54.7% | 4 | LOSS |
NYY@BOS | OVER 7.5 | 54.3% | 3 | WIN |
KC@PHI | PHI -130 | 58.3% | 4 | WIN |
LAD@SF | OVER 7.5 | 54.7% | 4 | LOSS |
NYM@PHI | PHI -122 | 55.6% | 4 | WIN |
KC@CLE | KC -104 | 52.0% | 3 | WIN |
CIN@SD | JAKE CRONEWORTH OVER 0.5 HITS | 53.1% | 3 | WIN |
WAS@MIA | MIA -123 | 55.2% | 4 | LOSS |
LAA@KC | UNDER 9.5 | 54.9% | 3 | WIN |
TEX@ARI | UNDER 9 | 54.2% | 4 | WIN |
SF@COL | UNDER 11.5 | 56.4% | 6 | LOSS |
SF@COL | RAFAEL DEVERS OVER 1.5 BASES | 56.1% | 6 | WIN |
MIA@WAS | WAS -110 | 54.4% | 4 | WIN |
NYM@DET | OVER 8.5 | 54.5% | 4 | WIN |
TEX@ARI | UNDER 9.5 | 56.4% | 6 | WIN |
TEX@ARI | ALEJANDRO OSUNA UNDER 1.5 BASES | 54.1% | 4 | LOSS |
ATL@CHC | CHC -116 | 55.1% | 3 | WIN |
PHI@MIL | OVER 8.5 | 55.0% | 3 | WIN |
ARI@LAD | SHOHEI OHTANI OVER 2.5 BASES | 54.2% | 4 | WIN |
SEA@CLE | CLE +1.5 | 57.2% | 3 | WIN |
CHC@SF | CHC -105 | 54.1% | 4 | LOSS |
NYY@CHW | RYAN MCMAHON OVER 0.5 BASES | 54.1% | 4 | WIN |