Cardinals vs. Pirates
Prediction, Odds & Props
Jun 30 | MLB AI Picks

Updated: 2025-06-28T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The St. Louis Cardinals (47–38) and the Pittsburgh Pirates (35–50) are set to open a three-game series at PNC Park on Monday, June 30, 2025, with first pitch scheduled for 6:40 p.m. ET. The Cardinals aim to continue their strong performance in the NL Central, while the Pirates look to rebound from recent struggles and gain momentum at home.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Jun 30, 2025

Start Time: 6:40 PM EST​

Venue: PNC Park​

Pirates Record: (35-50)

Cardinals Record: (47-38)

OPENING ODDS

STL Moneyline: -125

PIT Moneyline: +105

STL Spread: -1.5

PIT Spread: +1.5

Over/Under: 8.5

STL
Betting Trends

  • The Cardinals have covered the run line in 4 of their last 6 road games, reflecting their competitive performances away from home.

PIT
Betting Trends

  • The Pirates have failed to cover the run line in 5 of their last 7 home games, indicating challenges in securing wins at PNC Park.

MATCHUP TRENDS

  • The total has gone under in 4 of the last 6 meetings between the Cardinals and Pirates, suggesting a trend toward lower-scoring affairs in their recent matchups.

STL vs. PIT
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: S. Horwitz over 5 Fantasy Score.

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St. Louis vs Pittsburgh Prediction & Odds:
Free MLB Betting Insights for 6/30/25

Monday’s series opener between the St. Louis Cardinals and the Pittsburgh Pirates at PNC Park comes at a pivotal moment for both clubs, as the Cardinals look to strengthen their position in the NL Central and the Pirates attempt to right the ship after a string of disappointing results. St. Louis enters the contest with a 47–38 record, riding the momentum of solid play both at home and on the road, and they’ve covered the run line in four of their last six away games, suggesting they’ve found a formula for consistency. The Cardinals will hand the ball to Erick Fedde, who owns a 3–7 record with a 4.11 ERA and will be looking to improve upon his results by commanding the strike zone early and avoiding the long ball against a Pittsburgh lineup that lacks consistency but can do damage when given the chance. On the offensive side, St. Louis continues to benefit from the steady production of Brendan Donovan, who remains a table-setter in the top half of the lineup, while veterans like Paul Goldschmidt and Nolan Arenado provide leadership and power, even if their numbers have dipped slightly from past seasons. The Pirates, sitting at 35–50, are struggling to stay afloat and will counter with left-hander Andrew Heaney, who brings a 3–7 record and 4.48 ERA into the matchup, and his primary concern will be avoiding the kind of early trouble that has often plagued his starts.

Oneil Cruz is still a bright spot for Pittsburgh, contributing both power and athleticism, but the team as a whole has struggled to produce consistently with runners in scoring position, and that lack of timely hitting has often kept them from turning competitive games into wins. Pittsburgh has failed to cover the run line in five of their last seven home contests, a trend that underscores their current difficulties playing in front of their fans. Defensively, both teams are close in fielding percentage—St. Louis at .985 and Pittsburgh at .982—but execution in tight moments has often separated the contenders from the pretenders, and the Cardinals’ experience may give them the edge in that department. The total has gone under in four of the last six meetings between these teams, and with neither offense currently in peak form and both starters looking to grind out quality starts, this could be another low-scoring battle where execution in key at-bats defines the result. St. Louis will look to strike early against Heaney and lean on Fedde to keep things quiet through the middle innings, while Pittsburgh must find a way to break through against a Cardinals staff that has handled them well in recent meetings. With division implications more relevant to the Cardinals and the Pirates playing for pride and development, the urgency may vary, but expect a gritty and competitive opener between these familiar foes as each side seeks to control the tone of the series from the first pitch.

St. Louis Cardinals MLB Preview

The St. Louis Cardinals enter Monday’s series opener at PNC Park with a 47–38 record and clear momentum as they aim to strengthen their position in the NL Central and take advantage of a struggling Pittsburgh Pirates team. Having covered the run line in four of their last six road games, the Cardinals have shown a tendency to rise to the occasion in unfamiliar environments, largely due to a balanced mix of veteran leadership, emerging contributors, and reliable pitching. Brendan Donovan has been a standout presence at the top of the lineup, consistently getting on base and setting the table for Paul Goldschmidt and Nolan Arenado, both of whom continue to anchor the offense with their power and situational awareness despite somewhat reduced numbers compared to their career highs. Willson Contreras and Lars Nootbaar have also provided timely offense and defensive stability, giving the Cardinals multiple ways to produce runs. On the mound, Erick Fedde is expected to start, entering with a 3–7 record and a 4.11 ERA, and although he’s had his share of rocky outings, his recent command and pitch mix suggest potential for a bounce-back game, especially against a Pirates lineup that has been inconsistent and often struggles with runners in scoring position.

Fedde’s ability to get ahead in the count and induce weak contact will be crucial, particularly in limiting Oneil Cruz and Jack Suwinski, Pittsburgh’s two main power threats. Defensively, the Cardinals hold a .985 fielding percentage, ranking them in the lower third of the league, but they’ve generally played clean, efficient defense behind quality starts, which has allowed their bullpen to enter in manageable situations. That bullpen, featuring the likes of Ryan Helsley and Giovanny Gallegos, has been a quiet strength this season, regularly closing out games when given a late lead and playing a key role in tight road wins. St. Louis has also shown poise in late-game situations, with several comeback wins that speak to the clubhouse’s veteran poise and resilience. Against a Pirates team that has failed to cover the run line in five of its last seven home contests and has struggled to generate consistent offense, the Cardinals will aim to set the tone early with aggressive at-bats and smart base running. Manager Oliver Marmol has been strategic in lineup construction and bullpen deployment, often using platoon advantages to push the right buttons in key matchups. A win on Monday would be a strong start to what the Cardinals hope is a series sweep, especially with more challenging divisional opponents looming on the schedule. With the postseason push heating up and every game carrying increased weight, the Cardinals will approach this matchup with urgency and a clear focus on execution, knowing that beating teams below .500 is critical to maintaining playoff position and building the kind of momentum that carries through July and into August.

The St. Louis Cardinals (47–38) and the Pittsburgh Pirates (35–50) are set to open a three-game series at PNC Park on Monday, June 30, 2025, with first pitch scheduled for 6:40 p.m. ET. The Cardinals aim to continue their strong performance in the NL Central, while the Pirates look to rebound from recent struggles and gain momentum at home. St. Louis vs Pittsburgh AI Prediction: Free MLB Betting Insights for Jun 30. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Pittsburgh Pirates MLB Preview

The Pittsburgh Pirates return to PNC Park on Monday looking to regroup and regain footing as they host the surging St. Louis Cardinals, entering the matchup with a 35–50 record and having dropped five of their last seven home games against the spread, which underscores their ongoing struggles in front of their home fans. Despite flashes of promise from young talents like Oneil Cruz and steady veteran leadership from Andrew McCutchen, the Pirates have found it difficult to string together consistent performances, particularly when it comes to producing runs in key situations and maintaining stability on the mound. Cruz has remained a bright spot in the lineup, showing off his power and elite athleticism, while McCutchen recently made franchise history by passing Roberto Clemente on Pittsburgh’s all-time home run list—yet milestones alone haven’t been enough to reverse the team’s fortunes. Andrew Heaney, who will start Monday’s game, brings a 3–7 record and a 4.48 ERA into the contest and will be tasked with keeping a disciplined Cardinals lineup in check, something that will require both command and early control to avoid falling behind quickly. Heaney has struggled to avoid big innings this year, and against a St. Louis team that excels at working counts and capitalizing on mistakes, he’ll need to be sharp from the outset or risk another early exit.

Offensively, Pittsburgh has labored near the bottom of the league in runs per game, often relying on sporadic bursts rather than sustained rallies, and that inefficiency has cost them in winnable games where timely hitting would have made the difference. The supporting cast around Cruz and McCutchen has been inconsistent, with players like Bryan Reynolds and Ke’Bryan Hayes showing flashes but lacking the week-to-week production needed to drive winning streaks. Defensively, the Pirates have a .982 fielding percentage, ranking near the bottom of MLB, and defensive lapses have often compounded pitching issues, making it even tougher to stay competitive in close games. The bullpen, while featuring capable arms like David Bednar, has been overworked at times and put in difficult positions due to short outings by starters, which has exposed depth issues and contributed to several late-game collapses. Manager Derek Shelton continues to focus on player development and instilling fundamentals, but with a season now deep into its second half, the need to turn progress into results is more urgent than ever, especially against a divisional opponent like the Cardinals. To pull off a win, Pittsburgh will need Heaney to go at least six innings with minimal damage, the offense to cash in early chances, and the defense to play a clean game—all tall tasks, but not impossible given the parity in baseball and the pressure now on St. Louis to maintain their standing. For the Pirates, playing spoiler to a division rival could be just the motivation needed to spark a more competitive stretch, and Monday provides the kind of opportunity that could either kick off a turnaround or deepen the frustration of a season gone sideways.

St. Louis vs. Pittsburgh Prop Picks (AI)

AI algorithm Remi is pouring through tons of stats on each line. In fact, anytime the Cardinals and Pirates play there’s always several intriguing angles to key in on. Not to mention games played at PNC Park in Jun can often follow normal, predictable patterns.
Remi's searched hard and found the best prop for this matchup: S. Horwitz over 5 Fantasy Score.

St. Louis vs. Pittsburgh Prediction (AI)

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Remi, our AI sports genius, has been pouring over millions of data from every past game between the Cardinals and Pirates and using recursive machine learning and cutting-edge AI to examine the data to a single cover probability.

Interestingly enough, the data has been most keyed in on the linear correlation of emphasis knucklehead sportsbettors tend to put on Pittsburgh’s strength factors between a Cardinals team going up against a possibly unhealthy Pirates team. We’ve found the true game analytics might reflect a moderate lean against one Vegas line specifically.

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Below is our current AI St. Louis vs Pittsburgh picks, computer picks Cardinals vs Pirates, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
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Cardinals Betting Trends

The Cardinals have covered the run line in 4 of their last 6 road games, reflecting their competitive performances away from home.

Pirates Betting Trends

The Pirates have failed to cover the run line in 5 of their last 7 home games, indicating challenges in securing wins at PNC Park.

Cardinals vs. Pirates Matchup Trends

The total has gone under in 4 of the last 6 meetings between the Cardinals and Pirates, suggesting a trend toward lower-scoring affairs in their recent matchups.

St. Louis vs. Pittsburgh Game Info

St. Louis vs Pittsburgh starts on June 30, 2025 at 6:40 PM EST.

Spread: Pittsburgh +1.5
Moneyline: St. Louis -125, Pittsburgh +105
Over/Under: 8.5

St. Louis: (47-38)  |  Pittsburgh: (35-50)

Remi's searched hard and found the best prop for this matchup: S. Horwitz over 5 Fantasy Score.. Prices move—always shop for the best number.

The total has gone under in 4 of the last 6 meetings between the Cardinals and Pirates, suggesting a trend toward lower-scoring affairs in their recent matchups.

STL trend: The Cardinals have covered the run line in 4 of their last 6 road games, reflecting their competitive performances away from home.

PIT trend: The Pirates have failed to cover the run line in 5 of their last 7 home games, indicating challenges in securing wins at PNC Park.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

St. Louis vs. Pittsburgh Odds

AI algorithm Remi is pouring through tons of data points on each line. In fact, anytime the St. Louis vs Pittsburgh trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme temps rarely follow normal, predictable patterns.

St. Louis vs Pittsburgh Opening Odds

STL Moneyline: -125
PIT Moneyline: +105
STL Spread: -1.5
PIT Spread: +1.5
Over/Under: 8.5

St. Louis vs Pittsburgh Live Odds

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+240
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Philadelphia Phillies
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+165
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Washington Nationals
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+160
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O 8 (-105)
U 8 (-115)
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-110
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U 7.5 (-110)

MLB Past Picks

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We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers St. Louis Cardinals vs. Pittsburgh Pirates on June 30, 2025 at PNC Park.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
ARI@SD SD -131 57.3% 4 WIN
DET@BOS BOS -115 56.4% 5 WIN
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS