Phillies vs. Astros
Prediction, Odds & Props
Jun 26 | MLB AI Picks

Updated: 2025-06-24T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Philadelphia Phillies and Houston Astros will conclude their three-game series on Thursday, June 26, 2025, at Daikin Park in Houston. Both teams, leading their respective divisions, aim to secure the series win in this anticipated matchup.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Jun 26, 2025

Start Time: 2:10 PM EST​

Venue: Daikin Park​

Astros Record: (47-33)

Phillies Record: (47-33)

OPENING ODDS

PHI Moneyline: +122

HOU Moneyline: -145

PHI Spread: +1.5

HOU Spread: -1.5

Over/Under: 7

PHI
Betting Trends

  • The Phillies have an ATS record of 35–43, indicating challenges in covering the spread consistently this season.

HOU
Betting Trends

  • The Astros hold an ATS record of 35–43, reflecting similar struggles against the spread as the Phillies.

MATCHUP TRENDS

  • The Astros have been dominant at home, boasting a 29–13 record, and have a 16–7 record in games decided by one run, showcasing their ability to perform under pressure.

PHI vs. HOU
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: J. Pena over 5.5 Fantasy Score.

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Philadelphia vs Houston Prediction & Odds:
Free MLB Betting Insights for 6/26/25

The Philadelphia Phillies and Houston Astros are set to meet in the rubber match of their three-game series on Wednesday, June 26, 2025, at Daikin Park in Houston, with both clubs boasting identical 47–33 records and leading their respective divisions, making this game a high-stakes clash between two potential playoff contenders. With Cristopher Sánchez taking the mound for the Phillies and Hunter Brown getting the start for the Astros, the game is poised to be a tightly contested affair built around top-tier pitching, disciplined lineups, and elite-level bullpen execution. Philadelphia has quietly emerged as one of the most balanced teams in the National League, with Sánchez providing stability in the rotation thanks to his 6–2 record, 2.77 ERA, and 92 strikeouts over the first half of the season, and his recent outings have been dominant, holding hitters to a sub-.220 average. Backing him is an offense anchored by veterans like Kyle Schwarber and Trea Turner, with Schwarber’s power giving the lineup a constant home run threat and Turner’s versatility on the bases adding to their ability to manufacture runs. Philadelphia enters the game with a 23–16 road record and a recent trend of strong performance in series deciders, aided by a bullpen that has been sharp in high-leverage situations.

On the other side, Houston’s 29–13 home record is one of the best in baseball, and Hunter Brown has become the club’s ace with an 8–3 record, league-best 1.88 ERA, and 109 strikeouts while limiting opposing hitters to a .198 average, giving the Astros a significant edge whenever he pitches. The Astros lineup is equally potent, with timely hitting from players like Kyle Tucker and Yordan Álvarez, and their bullpen led by Josh Hader has been clinical, especially in close games where they hold a 16–7 record in one-run contests. Houston’s ability to close out games at home has been a major reason behind their consistent success, and they have covered the spread well as a favorite in tightly projected matchups. With both teams entering with identical win-loss records, this game serves as a potential postseason preview and will likely come down to which side can execute better in key moments, whether it’s a clutch at-bat in the seventh or a shutdown relief inning. Both teams are built for October and this late-June duel will test every strength—power vs power, bullpen depth vs bullpen depth, and managerial tactics that could impact playoff seeding. Expect a playoff atmosphere in Houston with every pitch carrying weight as these two evenly matched clubs battle not just for a series win but to prove their standing as one of the best in baseball.

Philadelphia Phillies MLB Preview

The Philadelphia Phillies enter Wednesday’s clash with the Houston Astros riding a wave of momentum and consistency that has made them one of the most well-rounded and dangerous teams in the National League this season. With a 47–33 record and a solid 23–16 mark on the road, the Phillies have shown they can win anywhere, largely thanks to their pitching depth, offensive balance, and defensive discipline. Cristopher Sánchez will get the start, bringing with him a 6–2 record and a sparkling 2.77 ERA through his first 15 starts, showing increased command and maturity on the mound while striking out 92 batters and limiting walks. Sánchez has been effective at getting ahead in counts and inducing weak contact, giving Philadelphia confidence that they can neutralize the potent Astros lineup in a high-stakes environment. Offensively, the Phillies are led by slugger Kyle Schwarber, who continues to deliver in big moments with his home run power, and shortstop Trea Turner, who’s hitting for average and producing runs both with his bat and his legs. Bryce Harper has also returned to form, giving the middle of the lineup even more firepower and protection, allowing others like Nick Castellanos and Alec Bohm to thrive. In close games, the Phillies’ bullpen has held its own with arms like José Alvarado and Jeff Hoffman providing key shutdown innings, while manager Rob Thomson has excelled at making strategic pitching changes and lineup adjustments.

Philadelphia’s recent trend in rubber matches is strong—they’ve won four of their last five Game 3s—thanks in part to their veteran leadership and ability to stay composed late in series. This club is built on more than just talent; it’s one of the most fundamentally sound and clutch-performing rosters in the league. They’ve been especially effective at covering spreads on the road when listed as underdogs, particularly in games with lower totals, which suggests confidence in their pitching and situational hitting. If Sánchez can hold Houston’s offense in check early, the Phillies should be well-positioned to pull off a series win behind a deep and battle-tested roster. Facing a tough starter like Hunter Brown won’t be easy, but the Phillies have consistently shown the patience and timely power needed to get to top-tier arms by the middle innings. This game is as much about execution as it is talent, and with a well-rounded roster, solid road record, and the desire to prove themselves against an American League powerhouse, the Phillies will treat this like a playoff tune-up. Every at-bat, every bullpen decision, and every run matters, and Philadelphia has the right blend of grit and experience to rise to the challenge in Houston.

The Philadelphia Phillies and Houston Astros will conclude their three-game series on Thursday, June 26, 2025, at Daikin Park in Houston. Both teams, leading their respective divisions, aim to secure the series win in this anticipated matchup. Philadelphia vs Houston AI Prediction: Free MLB Betting Insights for Jun 26. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Houston Astros MLB Preview

The Houston Astros return to Minute Maid Park on June 26 looking to secure a much-needed series win over the Philadelphia Phillies, with right-hander Hunter Brown taking the mound in what has been a resurgent stretch for both the pitcher and his club. Brown enters the matchup with a 4–5 record and a 4.56 ERA but has posted a dominant 1.40 ERA across his last four starts, showing significantly improved command and effectiveness with his off-speed pitches, especially his curveball and cutter. The Astros have leaned on his recent performances to stabilize a rotation that’s battled injuries and inconsistency for much of the season, and Brown’s recent success at home bodes well for a team that’s won 9 of its last 13 games at Minute Maid. Offensively, the Astros remain dangerous with a core that includes Jose Altuve, Yordan Álvarez, Kyle Tucker, and Alex Bregman, and while their power numbers are down slightly from recent seasons, they’re finding ways to manufacture runs through smart baserunning and situational hitting. Jeremy Peña and Chas McCormick have also provided timely contributions in the lower half of the order, giving Houston a more complete lineup that can pressure opposing pitchers from top to bottom. Despite an overall underwhelming start to the 2025 campaign, the Astros are showing signs of turning the corner with improved play on both sides of the ball, and their 21–17 record at home reflects growing consistency.

The bullpen remains a strong suit, anchored by closer Josh Hader and setup man Bryan Abreu, both of whom have been tough to hit in high-leverage spots. Houston has also performed well ATS in recent games when listed as a home favorite of -150 or less, particularly against teams with winning road records, suggesting the betting market is starting to respect their resurgence. This game against Philadelphia is not just another interleague matchup—it’s a benchmark for where this team stands against one of the National League’s top contenders. Manager Joe Espada continues to show growth in his first year at the helm, making sharp tactical decisions and keeping his veteran-laden clubhouse focused amid early adversity. With playoff expectations still very much alive, the Astros know that winning games against quality opponents like the Phillies at home is crucial to climbing back into the postseason picture. If Hunter Brown can continue to build on his hot streak and the offense can capitalize on early scoring chances, Houston will put itself in a strong position to take the series and continue their upward momentum heading into the second half of the season. This is a proud team with championship pedigree, and while the road back to October may be tougher this year, the pieces are beginning to fall into place for the Astros to make their move.

Philadelphia vs. Houston Prop Picks (AI)

Remi is pouring through loads of datapoints on each player. In fact, anytime the Phillies and Astros play there’s always several intriguing observations to key in on. Not to mention games played at Daikin Park in Jun can often follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: J. Pena over 5.5 Fantasy Score.

Philadelphia vs. Houston Prediction (AI)

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Remi, our AI sports genius, has been pouring over millions of data from every angle between the Phillies and Astros and using recursive machine learning and kick-ass AI to boil down the data to a single cover probability.

The Algorithm has been most keyed in on the unproportionally assigned factor human bettors tend to put on coaching factors between a Phillies team going up against a possibly deflated Astros team. It appears the true game analytics appear to reflect a strong lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI Philadelphia vs Houston picks, computer picks Phillies vs Astros, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
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Phillies Betting Trends

The Phillies have an ATS record of 35–43, indicating challenges in covering the spread consistently this season.

Astros Betting Trends

The Astros hold an ATS record of 35–43, reflecting similar struggles against the spread as the Phillies.

Phillies vs. Astros Matchup Trends

The Astros have been dominant at home, boasting a 29–13 record, and have a 16–7 record in games decided by one run, showcasing their ability to perform under pressure.

Philadelphia vs. Houston Game Info

Philadelphia vs Houston starts on June 26, 2025 at 2:10 PM EST.

Spread: Houston -1.5
Moneyline: Philadelphia +122, Houston -145
Over/Under: 7

Philadelphia: (47-33)  |  Houston: (47-33)

Remi's searched hard and found the best prop for this matchup: J. Pena over 5.5 Fantasy Score.. Prices move—always shop for the best number.

The Astros have been dominant at home, boasting a 29–13 record, and have a 16–7 record in games decided by one run, showcasing their ability to perform under pressure.

PHI trend: The Phillies have an ATS record of 35–43, indicating challenges in covering the spread consistently this season.

HOU trend: The Astros hold an ATS record of 35–43, reflecting similar struggles against the spread as the Phillies.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

Philadelphia vs. Houston Odds

Remi is pouring through tons of stats on each team. In fact, anytime the Philadelphia vs Houston trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme altitude seemingly never follow normal, predictable patterns.

Philadelphia vs Houston Opening Odds

PHI Moneyline: +122
HOU Moneyline: -145
PHI Spread: +1.5
HOU Spread: -1.5
Over/Under: 7

Philadelphia vs Houston Live Odds

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7
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-50000
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-2.5 (-800)
+2.5 (+450)
O 13.5 (-105)
U 13.5 (-125)
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1
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-4.5 (+132)
O 8.5 (+124)
U 8.5 (-166)
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-350
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O 8.5 (-114)
U 8.5 (-114)
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Los Angeles Dodgers
Seattle Mariners
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0
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+118
-150
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U 4.5 (+110)
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Kansas City Royals
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Sep 28, 2025 3:06PM EDT
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New York Yankees
9/28/25 3:06PM
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+160
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O 8.5 (-122)
U 8.5 (+100)
Sep 28, 2025 3:06PM EDT
Colorado Rockies
San Francisco Giants
9/28/25 3:06PM
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+240
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U 7.5 (-110)
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Minnesota Twins
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9/28/25 3:06PM
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+180
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O 8 (-122)
U 8 (+100)
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Chicago White Sox
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9/28/25 3:06PM
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-102
-116
-1.5 (+164)
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O 8.5 (-115)
U 8.5 (-105)
Sep 28, 2025 3:08PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/28/25 3:08PM
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+166
-198
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O 7.5 (-122)
U 7.5 (+100)
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Los Angeles Dodgers
Seattle Mariners
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-108
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O 8 (-115)
U 8 (-105)
Sep 28, 2025 3:11PM EDT
Cincinnati Reds
Milwaukee Brewers
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+110
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O 7.5 (-115)
U 7.5 (-105)
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Pittsburgh Pirates
Atlanta Braves
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+184
-220
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O 7.5 (-105)
U 7.5 (-115)
Sep 28, 2025 3:20PM EDT
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+101
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MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Philadelphia Phillies vs. Houston Astros on June 26, 2025 at Daikin Park.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
ARI@SD SD -131 57.3% 4 WIN
DET@BOS BOS -115 56.4% 5 WIN
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS