Pirates vs. Brewers
Prediction, Odds & Props
Jun 25 | MLB AI Picks

Updated: 2025-06-23T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Pittsburgh Pirates and Milwaukee Brewers wrap up their three-game series on Wednesday, June 25, 2025, at American Family Field. Both teams are vying for a series win, with the Brewers aiming to solidify their position in the NL Central and the Pirates looking to gain momentum.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Jun 25, 2025

Start Time: 2:10 PM EST​

Venue: American Family Field​

Brewers Record: (44-36)

Pirates Record: (32-49)

OPENING ODDS

PIT Moneyline: -116

MIL Moneyline: -104

PIT Spread: -1.5

MIL Spread: +1.5

Over/Under: 6.5

PIT
Betting Trends

  • The Pittsburgh Pirates have covered the run line in 3 of their last 5 games, indicating a moderate performance against the spread recently.

MIL
Betting Trends

  • The Milwaukee Brewers have hit the game total under in 36 of their last 60 games, suggesting a trend towards lower-scoring games.

MATCHUP TRENDS

  • The Brewers have a 43-36 record this season, placing them second in the NL Central, while the Pirates stand at 29-45, highlighting the competitive disparity between the teams.

PIT vs. MIL
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: S. Horwitz over 0.5 Hits+Runs+RBI.

LIVE MLB ODDS

MLB ODDS COMPARISON

WANT MORE AI PICKS?

VAULT
VS. SPREAD
308-221
VAULT
NET UNITS
(INCL VIG)
+418
VAULT
NET PROFIT
(INCL VIG)
$100/UNIT
$41,803
EXECUTIVE
VS. SPREAD
1551-1329
EXECUTIVE
NET UNITS
(INCL VIG)
+365.7
EXECUTIVE
NET PROFIT
(INCL VIG)
$100/UNIT
$36,569

AI SPORTS PICK PRODUCTS

Create a Free Account

‘Create an Account’ to Get Remi’s Picks Today.

Remi Finds New Picks

Remi calculates the probability a team will cover the line.

Remi Works 24/7

Remi uses this probability to assign units to each pick.

Get Remi's AI Picks

Get Remi’s Top AI Sports Picks sent direct to your inbox.

Pittsburgh vs Milwaukee Prediction & Odds:
Free MLB Betting Insights for 6/25/25

The Pittsburgh Pirates and Milwaukee Brewers conclude their three-game series on Wednesday, June 25, 2025, at American Family Field. The Brewers, with a 43-36 record, are vying to solidify their position in the National League Central, while the Pirates, at 30-48, aim to build momentum for the remainder of the season. The Brewers have demonstrated strong home performance, with a 23-15 record at American Family Field, and have been particularly effective in the first five innings, often establishing early leads. Their offense has been bolstered by Christian Yelich, who leads the team with 14 home runs and 43 RBIs, and a pitching staff that has maintained a team ERA of 3.78, ranking them among the top in the league. On the other hand, the Pirates have faced challenges on the road, with an 11-27 away record, and have struggled offensively, ranking near the bottom of the league in key batting metrics. However, they have found a bright spot in rookie pitcher Paul Skenes, who boasts a 1.85 ERA and has been a consistent performer on the mound. The Pirates have also shown resilience, covering the run line in 3 of their last 5 games, indicating a potential to keep games competitive. As both teams take the field for the series finale, the matchup presents an opportunity for the Brewers to capitalize on their home advantage and for the Pirates to leverage their emerging talent to challenge a division rival.

Pittsburgh Pirates MLB Preview

The Pittsburgh Pirates come into this game against the Milwaukee Brewers on June 25, 2025 with a record of 32-48 and a strong desire to find some rhythm on the road after what has been a difficult first half of the season, especially when it comes to generating consistent offensive production. The Pirates have spent most of the year hovering near the bottom of the National League Central, mostly due to their struggles at the plate, where they rank near the bottom of the league with a team batting average hovering around .225 and a lack of timely hitting that has left them unable to give their talented pitching staff the kind of run support that could lead to more competitive results. Even with promising contributions from veteran outfielder Bryan Reynolds and the occasional spark from Andrew McCutchen, the offense has failed to string together consistent at-bats or generate sustained scoring opportunities across the depth of their lineup. On the pitching side, however, Pittsburgh has had some bright spots, most notably rookie sensation Paul Skenes, who has quickly established himself as one of the most exciting young arms in the game with a 1.85 ERA and an impressive strikeout rate that suggests he could become the cornerstone of their rotation for years to come. Skenes and other capable arms have kept the Pirates competitive in many games despite a lack of run support, and their team ERA of 3.85 — while not elite — reflects a club that can keep games within reach if they can just put a few more runs on the board.

The Pirates have also shown some signs of fight recently, covering the run line in three of their last five games, which speaks to their ability to hang around and put pressure on opponents, especially early. Away from PNC Park, though, they’ve been more vulnerable, posting an 11-27 record on the road that underscores the challenges they face when stepping into hostile environments. Despite these struggles, the Pirates will look to jump on a Brewers team that can sometimes give up early runs and hope to leverage their strong arms to keep the game close into the late innings, knowing that one big swing from one of their better hitters could be enough to change the outcome. Building momentum with a disciplined plate approach and making the most of their scoring chances will be the key for Pittsburgh as they aim to compete in this game and perhaps gain some much-needed confidence that can carry into future series. The road to relevance may still be long for this club, but games like this offer a chance to grow together and learn how to navigate the kind of high-leverage situations that will define the Pirates’ future as they continue to build around their promising core and strive for better days ahead.

The Pittsburgh Pirates and Milwaukee Brewers wrap up their three-game series on Wednesday, June 25, 2025, at American Family Field. Both teams are vying for a series win, with the Brewers aiming to solidify their position in the NL Central and the Pirates looking to gain momentum. Pittsburgh vs Milwaukee AI Prediction: Free MLB Betting Insights for Jun 25. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Milwaukee Brewers MLB Preview

The Milwaukee Brewers enter their June 25, 2025, matchup against the Pittsburgh Pirates with a 44–36 record, positioning them second in the National League Central Division and firmly in contention for a postseason berth. Their success has been driven by a combination of consistent pitching and a balanced offensive lineup. The pitching staff boasts a team ERA of 3.78, ranking them among the top in the league, with standout performances from Freddy Peralta, who leads the team with a 2.76 ERA and 90 strikeouts over 88 innings. Rookie sensation Jacob Misiorowski has also made headlines with his dominant debut, delivering 11 hitless innings over two starts and showcasing a fastball that reaches up to 103 mph. Offensively, the Brewers have a team batting average of .243, with Christian Yelich leading the charge, posting a .263 average, 15 home runs, and 56 RBIs. Supporting him are Sal Frelick and Brice Turang, who contribute with batting averages of .293 and .274, respectively, adding depth to the lineup. The Brewers have been particularly strong at home, holding a 24–16 record at American Family Field, and have demonstrated resilience in close games, often relying on their bullpen to secure victories. As they face the Pirates, the Brewers aim to capitalize on their home-field advantage and continue their push towards the top of the division standings.  

Pittsburgh vs. Milwaukee Prop Picks (AI)

Remi is pouring through tons of stats on each line. In fact, anytime the Pirates and Brewers play there’s always several intriguing trends to key in on. Not to mention games played at American Family Field in Jun rarely follow normal, predictable patterns.
Remi's searched hard and found the best prop for this matchup: S. Horwitz over 0.5 Hits+Runs+RBI.

Pittsburgh vs. Milwaukee Prediction (AI)

Remi Robot Icon

Remi, our AI sports wizard, has been pouring over exorbitant amounts of data from every angle between the Pirates and Brewers and using recursive machine learning and cutting-edge AI to examine the data to a single cover probability.

The Algorithm has been most watching on the trending weight knucklehead sportsbettors regularly put on player performance factors between a Pirates team going up against a possibly strong Brewers team. Trends look to say the true game analytics might reflect a moderate lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI Pittsburgh vs Milwaukee picks, computer picks Pirates vs Brewers, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
MLB 9/26 DET@BOS UNLOCK THIS PICK 5 EXECUTIVE Locked EXECUTIVE
MLB 9/26 BAL@NYY UNLOCK THIS PICK 4 INTEL Locked INTEL
MLB 9/26 ARI@SD UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
MLB 9/26 NYM@MIA UNLOCK THIS PICK 1 INTEL Locked INTEL
MLB 9/26 NYM@MIA GET FREE PICK NOW 1
MLB 9/26 COL@SF UNLOCK THIS PICK 0 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

Pirates Betting Trends

The Pittsburgh Pirates have covered the run line in 3 of their last 5 games, indicating a moderate performance against the spread recently.

Brewers Betting Trends

The Milwaukee Brewers have hit the game total under in 36 of their last 60 games, suggesting a trend towards lower-scoring games.

Pirates vs. Brewers Matchup Trends

The Brewers have a 43-36 record this season, placing them second in the NL Central, while the Pirates stand at 29-45, highlighting the competitive disparity between the teams.

Pittsburgh vs. Milwaukee Game Info

Pittsburgh vs Milwaukee starts on June 25, 2025 at 2:10 PM EST.

Venue: American Family Field.

Spread: Milwaukee +1.5
Moneyline: Pittsburgh -116, Milwaukee -104
Over/Under: 6.5

Pittsburgh: (32-49)  |  Milwaukee: (44-36)

Remi's searched hard and found the best prop for this matchup: S. Horwitz over 0.5 Hits+Runs+RBI.. Prices move—always shop for the best number.

The Brewers have a 43-36 record this season, placing them second in the NL Central, while the Pirates stand at 29-45, highlighting the competitive disparity between the teams.

PIT trend: The Pittsburgh Pirates have covered the run line in 3 of their last 5 games, indicating a moderate performance against the spread recently.

MIL trend: The Milwaukee Brewers have hit the game total under in 36 of their last 60 games, suggesting a trend towards lower-scoring games.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

Pittsburgh vs. Milwaukee Odds

AI algorithm Remi is pouring through tons of stats on each player. In fact, anytime the Pittsburgh vs Milwaukee trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme altitude seemingly never follow normal, predictable patterns.

Pittsburgh vs Milwaukee Opening Odds

PIT Moneyline: -116
MIL Moneyline: -104
PIT Spread: -1.5
MIL Spread: +1.5
Over/Under: 6.5

Pittsburgh vs Milwaukee Live Odds

Games PTS ML SPR O/U
Sep 27, 2025 1:06PM EDT
Baltimore Orioles
New York Yankees
9/27/25 1:06PM
Orioles
Yankees
+194
-235
+1.5 (-105)
-1.5 (-114)
O 8.5 (-122)
U 8.5 (+100)
Sep 27, 2025 2:21PM EDT
St Louis Cardinals
Chicago Cubs
9/27/25 2:21PM
Cardinals
Cubs
 
-168
 
-1.5 (+118)
O 9 (-122)
U 9 (+100)
Sep 27, 2025 3:09PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/27/25 3:09PM
Rays
Blue Jays
+132
-156
+1.5 (-154)
-1.5 (+128)
O 8.5 (-106)
U 8.5 (-114)
Sep 27, 2025 4:06PM EDT
Chicago White Sox
Washington Nationals
9/27/25 4:06PM
White Sox
Nationals
+102
-120
-1.5 (+162)
+1.5 (-196)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 4:06PM EDT
Colorado Rockies
San Francisco Giants
9/27/25 4:06PM
Rockies
Giants
+198
-240
+1.5 (-110)
-1.5 (-110)
O 8 (-108)
U 8 (-112)
Sep 27, 2025 4:11PM EDT
New York Mets
Miami Marlins
9/27/25 4:11PM
Mets
Marlins
-124
+106
-1.5 (+130)
+1.5 (-156)
O 8.5 (-112)
U 8.5 (-108)
Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
+177
-197
+1.5 (-118)
-1.5 (-102)
O 8.5 (-118)
U 8.5 (-102)
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
+128
-152
+1.5 (-178)
-1.5 (+146)
O 7.5 (-120)
U 7.5 (-102)
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
+143
-158
+1.5 (-150)
-1.5 (+130)
O 8.5 (+100)
U 8.5 (-120)
Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
+132
-156
+1.5 (-172)
-1.5 (+142)
O 7 (-120)
U 7 (-102)
Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
+120
-132
+1.5 (-180)
-1.5 (+157)
O 7.5 (-115)
U 7.5 (-105)
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
+102
-120
+1.5 (-215)
-1.5 (+180)
O 7.5 (-110)
U 7.5 (-110)
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
+104
-115
+1.5 (-185)
-1.5 (+161)
O 10 (-110)
U 10 (-110)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Pittsburgh Pirates vs. Milwaukee Brewers on June 25, 2025 at American Family Field.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS
CIN@ARI KEBRYAN HAYES STRIKEOUTS UNDER 0.5 56.2% 6 WIN
LAD@SD SD +110 50.9% 6 WIN