Diamondbacks vs. White Sox
Prediction, Odds & Props
Jun 24 | MLB AI Picks

Updated: 2025-06-22T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Arizona Diamondbacks and Chicago White Sox are set to face off on Tuesday, June 24, 2025, at Guaranteed Rate Field in Chicago. The Diamondbacks, with a 39–37 record, aim to strengthen their position in the NL Wild Card race, while the White Sox, at 24–53, look to snap a five-game home losing streak.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Jun 24, 2025

Start Time: 7:40 PM EST​

Venue: Rate Field​

White Sox Record: (25-54)

Diamondbacks Record: (40-38)

OPENING ODDS

ARI Moneyline: -140

CHW Moneyline: +118

ARI Spread: -1.5

CHW Spread: +1.5

Over/Under: 9

ARI
Betting Trends

  • The Diamondbacks have a 20–17 record against the spread (ATS) in away games this season, indicating a solid performance on the road.

CHW
Betting Trends

  • The White Sox have struggled at home, with a 16–21 record, and are currently on a five-game home losing streak.

MATCHUP TRENDS

  • The Diamondbacks have a 25–20–3 record as favorites, while the White Sox are 13–13 as underdogs, suggesting a potential edge for Arizona in this matchup.

ARI vs. CHW
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: R. Nelson under 29.5 Fantasy Score.

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Arizona vs Chicago White Sox Prediction & Odds:
Free MLB Betting Insights for 6/24/25

The Arizona Diamondbacks and Chicago White Sox are set to face off in an interleague battle at Guaranteed Rate Field on June 24, 2025, as both teams navigate drastically different trajectories this season. The Diamondbacks are fighting for postseason relevance in the National League, sitting around the .500 mark with a balanced roster and recent momentum sparked by Eugenio Suárez’s explosive bat. On the other side, the White Sox have endured a dismal 2025 campaign, struggling mightily at home and sitting well below .500 overall, though flashes of young talent and occasional offensive bursts have provided brief reprieves. Arizona enters this matchup with Ryne Nelson projected to start, who has quietly provided stability in the rotation with a sub-4.00 ERA and has kept hitters off balance with his fastball command and secondary offerings. For the White Sox, Jordan Leasure is expected to get the nod despite battling inconsistency this season; his ERA sits just above 4.20, and he’s trying to find consistency after being shuffled in and out of various bullpen and starting roles. From an offensive standpoint, the Diamondbacks have demonstrated clutch hitting in recent games, with Suárez crushing four home runs in a week, Ketel Marte anchoring the middle of the lineup, and Corbin Carroll offering speed and contact skills at the top of the order.

The White Sox offense, meanwhile, has leaned on Miguel Vargas, who has lifted his average significantly and provides reliable contact hitting, while Luis Robert Jr. remains a wild card with power upside despite battling injuries. The D-backs also boast a more reliable bullpen and overall team defense, while Chicago’s defensive metrics have been a liability in several close games. Statistically, Arizona enters as a favorite, with a better road ATS record and a recent track record of success when scoring at least four runs, whereas the White Sox have struggled to score consistently and protect leads late in games. Both teams are navigating different phases of competitive cycles—Arizona building a playoff push, Chicago focused on youth development and long-term restructuring—making this a telling series for each. The D-backs will look to capitalize on a vulnerable White Sox pitching staff and defense, while Chicago’s best chance for a win may come from a surprise offensive outburst or a lights-out performance from Leasure. Ultimately, the edge lies with Arizona due to superior pitching depth, offensive consistency, and recent form, but as always in baseball, a few key at-bats or defensive plays could sway the result in either direction. This game could either be another tough chapter in the White Sox’s long 2025 campaign or a much-needed win to disrupt Arizona’s playoff chase.

Arizona Diamondbacks MLB Preview

The Arizona Diamondbacks enter their June 24, 2025 matchup against the Chicago White Sox as a team with postseason aspirations and a roster built for both power and athleticism, looking to take advantage of a struggling opponent and continue gaining momentum in the National League race. Arizona has hovered around the .500 mark for much of the season but has shown signs of heating up lately, especially behind the power bat of Eugenio Suárez, who has erupted with multiple home runs in recent games and helped reignite the team’s offense. Ketel Marte has remained one of the most reliable contributors in the lineup, balancing power and plate discipline, while Corbin Carroll provides energy at the top of the order with his speed, contact ability, and advanced base running. The Diamondbacks’ lineup also features a blend of young potential and veteran poise, and their offense tends to thrive when generating early traffic on the bases. On the mound, Ryne Nelson is expected to start and has quietly posted a solid campaign, keeping his ERA under control and minimizing damage by attacking the strike zone early and avoiding big innings. His recent starts have included strong outings against playoff-contending lineups, making him a clear advantage in this matchup.

Arizona’s bullpen, anchored by closer Paul Sewald, offers a reliable back-end solution that has helped the team win close games throughout the year, especially in late innings where their defense also holds up well. The D-backs have been a respectable team on the road, including a solid ATS showing away from Chase Field, often playing smart, situational baseball that translates well in hostile environments. They’ve also benefited from a manager in Torey Lovullo who isn’t afraid to leverage platoons or call on aggressive base running tactics to pressure defenses like Chicago’s, which have often faltered under duress this year. If Arizona can jump ahead early and turn the game over to their bullpen with a lead, they’ll be in strong position to come out with a win. While they haven’t run away in their division standings, every series against sub-.500 teams like the White Sox becomes crucial in a tightly contested wild card race. Their key to victory lies in maintaining their current offensive rhythm, keeping the ball in play to expose the White Sox’s defensive weaknesses, and letting their pitching staff do the rest. A win in this game not only helps pad their win column but also builds confidence and momentum heading into the more difficult stretch of the summer schedule, making it imperative that Arizona plays clean, crisp, and focused baseball from the first pitch.

The Arizona Diamondbacks and Chicago White Sox are set to face off on Tuesday, June 24, 2025, at Guaranteed Rate Field in Chicago. The Diamondbacks, with a 39–37 record, aim to strengthen their position in the NL Wild Card race, while the White Sox, at 24–53, look to snap a five-game home losing streak. Arizona vs Chicago White Sox AI Prediction: Free MLB Betting Insights for Jun 24. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Chicago White Sox White Sox MLB Preview

The Chicago White Sox return home on June 24, 2025 to face the Arizona Diamondbacks amid a season of transition and frustration, looking for any spark to break the cycle of underperformance that has plagued them for much of the year. Chicago remains entrenched near the bottom of the AL Central standings, beset by injuries, inconsistent pitching, and a lineup that has struggled to produce with runners in scoring position. Offensively, the team has relied heavily on Eloy Jiménez and Luis Robert Jr., though both have had stretches of inconsistency and health issues that have stifled any sustained momentum. Andrew Vaughn has shown flashes of becoming the middle-of-the-order threat the organization hoped for, but his power numbers remain modest, and the lack of depth around him in the lineup allows opposing pitchers to pitch around him or attack less dangerous parts of the order. The White Sox have particularly struggled against right-handed pitching, which doesn’t bode well as they prepare to face Ryne Nelson and a Diamondbacks pitching staff that tends to pound the zone and force weak contact. On the mound, the White Sox are expected to send Erick Fedde to the hill, who has had a mixed campaign with some strong outings against weaker lineups but has often found himself in trouble due to elevated pitch counts and occasional control issues.

The bullpen, once viewed as a strength, has faltered under the weight of too many high-leverage situations created by short outings from the rotation and a lack of run support. Defensively, Chicago has been among the league’s worst, committing costly errors and failing to convert routine plays into outs, an issue that consistently places additional pressure on the pitching staff. At home, the White Sox have been slightly more competitive but still remain below .500 ATS and often struggle to keep pace when facing playoff-caliber opponents. While manager Pedro Grifol has attempted to instill a more aggressive and disciplined mindset, the results have yet to materialize consistently on the field. With the team clearly in rebuild or retool mode, younger players such as Colson Montgomery and Bryan Ramos are slowly seeing more playing time, though their impact has been modest as they adjust to big-league pitching. The White Sox’s best chance in this matchup is to keep the game close early, avoid giving away outs defensively, and hope that a few timely hits can spark a rare offensive outburst. However, if the offense continues to sputter and the defense cannot contain Arizona’s dynamic base runners, the White Sox are likely to find themselves playing from behind once again. In front of a fan base that’s increasingly grown restless with the organization’s direction, every game becomes an opportunity to demonstrate fight and evaluate future core players, but the path to victory remains narrow unless both the bats and gloves wake up in unison.

Arizona vs. Chicago White Sox Prop Picks (AI)

Remi is pouring through loads of datapoints on each player. In fact, anytime the Diamondbacks and White Sox play there’s always several intriguing trends to key in on. Not to mention games played at Rate Field in Jun almost always follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: R. Nelson under 29.5 Fantasy Score.

Arizona vs. Chicago White Sox Prediction (AI)

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Remi, our AI sports genius, has been pouring over mountains of data from every past game between the Diamondbacks and White Sox and using recursive machine learning and kick-ass AI to analyze the data to a single cover probability.

Interestingly enough, the data has been most watching on the trending factor emotional bettors tend to put on Chicago White Sox’s strength factors between a Diamondbacks team going up against a possibly tired White Sox team. In reality, the true game analytics appear to reflect a slight lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI Arizona vs Chicago White Sox picks, computer picks Diamondbacks vs White Sox, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
MLB 9/26 DET@BOS UNLOCK THIS PICK 5 EXECUTIVE Locked EXECUTIVE
MLB 9/26 BAL@NYY UNLOCK THIS PICK 4 INTEL Locked INTEL
MLB 9/26 ARI@SD UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
MLB 9/26 NYM@MIA UNLOCK THIS PICK 1 INTEL Locked INTEL
MLB 9/26 NYM@MIA GET FREE PICK NOW 1
MLB 9/26 COL@SF UNLOCK THIS PICK 0 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

Diamondbacks Betting Trends

The Diamondbacks have a 20–17 record against the spread (ATS) in away games this season, indicating a solid performance on the road.

White Sox Betting Trends

The White Sox have struggled at home, with a 16–21 record, and are currently on a five-game home losing streak.

Diamondbacks vs. White Sox Matchup Trends

The Diamondbacks have a 25–20–3 record as favorites, while the White Sox are 13–13 as underdogs, suggesting a potential edge for Arizona in this matchup.

Arizona vs. Chicago White Sox Game Info

Arizona vs Chicago White Sox starts on June 24, 2025 at 7:40 PM EST.

Spread: Chicago White Sox +1.5
Moneyline: Arizona -140, Chicago White Sox +118
Over/Under: 9

Arizona: (40-38)  |  Chicago White Sox: (25-54)

Remi's searched hard and found the best prop for this matchup: R. Nelson under 29.5 Fantasy Score.. Prices move—always shop for the best number.

The Diamondbacks have a 25–20–3 record as favorites, while the White Sox are 13–13 as underdogs, suggesting a potential edge for Arizona in this matchup.

ARI trend: The Diamondbacks have a 20–17 record against the spread (ATS) in away games this season, indicating a solid performance on the road.

CHW trend: The White Sox have struggled at home, with a 16–21 record, and are currently on a five-game home losing streak.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

Arizona vs. Chicago White Sox Odds

AI algorithm Remi is pouring through mountains of data points on each team. In fact, anytime the Arizona vs Chicago White Sox trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme hostile environments almost always follow normal, predictable betting trends.

Arizona vs Chicago White Sox Opening Odds

ARI Moneyline: -140
CHW Moneyline: +118
ARI Spread: -1.5
CHW Spread: +1.5
Over/Under: 9

Arizona vs Chicago White Sox Live Odds

Games PTS ML SPR O/U
Sep 27, 2025 1:06PM EDT
Baltimore Orioles
New York Yankees
9/27/25 1:06PM
Orioles
Yankees
+194
-235
+1.5 (-105)
-1.5 (-114)
O 8.5 (-122)
U 8.5 (+100)
Sep 27, 2025 2:21PM EDT
St Louis Cardinals
Chicago Cubs
9/27/25 2:21PM
Cardinals
Cubs
 
-168
 
-1.5 (+118)
O 9 (-122)
U 9 (+100)
Sep 27, 2025 3:09PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/27/25 3:09PM
Rays
Blue Jays
+132
-156
+1.5 (-154)
-1.5 (+128)
O 8.5 (-106)
U 8.5 (-114)
Sep 27, 2025 4:06PM EDT
Chicago White Sox
Washington Nationals
9/27/25 4:06PM
White Sox
Nationals
+102
-120
-1.5 (+162)
+1.5 (-196)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 4:06PM EDT
Colorado Rockies
San Francisco Giants
9/27/25 4:06PM
Rockies
Giants
+198
-240
+1.5 (-110)
-1.5 (-110)
O 8 (-108)
U 8 (-112)
Sep 27, 2025 4:11PM EDT
New York Mets
Miami Marlins
9/27/25 4:11PM
Mets
Marlins
-124
+106
-1.5 (+130)
+1.5 (-156)
O 8.5 (-112)
U 8.5 (-108)
Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
+177
-197
+1.5 (-118)
-1.5 (-102)
O 8.5 (-118)
U 8.5 (-102)
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
+128
-152
+1.5 (-178)
-1.5 (+146)
O 7.5 (-120)
U 7.5 (-102)
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
+143
-158
+1.5 (-150)
-1.5 (+130)
O 8.5 (+100)
U 8.5 (-120)
Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
+132
-156
+1.5 (-172)
-1.5 (+142)
O 7 (-120)
U 7 (-102)
Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
+120
-132
+1.5 (-180)
-1.5 (+157)
O 7.5 (-115)
U 7.5 (-105)
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
+102
-120
+1.5 (-215)
-1.5 (+180)
O 7.5 (-110)
U 7.5 (-110)
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
+104
-115
+1.5 (-185)
-1.5 (+161)
O 10 (-110)
U 10 (-110)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Arizona Diamondbacks vs. Chicago White Sox White Sox on June 24, 2025 at Rate Field.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS
CIN@ARI KEBRYAN HAYES STRIKEOUTS UNDER 0.5 56.2% 6 WIN
LAD@SD SD +110 50.9% 6 WIN