The Chicago White Sox will take the field on June 23, 2025, against the visiting Arizona Diamondbacks, looking to salvage what has been a long and discouraging season by snapping a losing stretch and showing signs of life in front of their home crowd at Guaranteed Rate Field. At 25–53, the White Sox are locked near the bottom of the American League standings, with a rebuild fully underway and a roster filled with young, untested talent trying to make a case for future roles. Offensively, Chicago has been anemic for much of the season, failing to consistently generate multi-run innings or take advantage of scoring opportunities, particularly in tight contests where they have a dismal 5–21 record in one-run games. Veterans like Andrew Benintendi and Paul DeJong have shown flashes of production, but without consistent support around them in the lineup, the White Sox often struggle to keep pace with more complete clubs like Arizona. Top prospect Oscar Colás and young infielder Bryan Ramos are receiving more playing time and will be expected to contribute against a Diamondbacks pitching staff that limits mistakes and induces a high percentage of ground balls. The White Sox are expected to start a fringe rotation arm or converted reliever—possibly Adrian Houser or a bullpen opener—none of whom have offered stability through more than four innings this season, which puts immediate stress on a relief corps that has ranked near the bottom in ERA, WHIP, and save percentage.

Defensively, Chicago has improved slightly over the past month with more consistent play in the infield, but miscommunications and throwing errors have still cropped up, particularly when the game’s tempo increases and pressure mounts in the later innings. Against Arizona’s aggressive baserunners and fundamentally sound defense, the White Sox will need to play close to mistake-free baseball just to keep pace. The home crowd has been understandably restless, with low attendance numbers and frequent late-game collapses souring the mood, but there remains hope that some of the younger players can provide sparks of excitement and begin building the foundation for 2026 and beyond. The key to any chance of a White Sox upset lies in an early offensive burst—if they can string together a few hits and gain confidence early, they may be able to outslug Arizona in a one-off shootout—but more likely, they’ll find themselves needing to rally against a deeper and more polished bullpen. Manager Pedro Grifol continues to juggle lineups and bullpen matchups in search of any edge, but with the team’s lack of depth and high-leverage reliability, wins are still hard to come by. If the White Sox are going to challenge Arizona, they’ll need strong situational hitting, clean defensive play, and a rare standout performance on the mound to hold off a Diamondbacks club that’s far more cohesive and experienced in executing late-game strategies.