Orioles vs. Yankees
Prediction, Odds & Props
Jun 22 | MLB AI Picks

Updated: 2025-06-20T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

Saturday’s showdown at Yankee Stadium pits the Baltimore Orioles against the New York Yankees in a pivotal late-June clash. First pitch is set for 11:35 a.m. ET on June 22, 2025. New York opens as a strong home favorite, with the total around 9.5 runs—a line that suggests a balanced, moderately high-scoring game.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Jun 22, 2025

Start Time: 11:35 AM​

Venue: Yankee Stadium​

Yankees Record: (44-32)

Orioles Record: (33-43)

OPENING ODDS

BAL Moneyline: +160

NYY Moneyline: -193

BAL Spread: +1.5

NYY Spread: -1.5

Over/Under: 9.5

BAL
Betting Trends

  • Baltimore sits at 32–42 ATS for the season, but they’ve gone 5–8 ATS at Yankee Stadium this weekend and have covered five of their last ten games, showing resilience even as underdogs.

NYY
Betting Trends

  • New York is 34–40 ATS overall and 6–4 in their last ten games. As favorites of –189 or better, they’re 13–8 this season and have covered in eight of their last ten starts.

MATCHUP TRENDS

  • Yankees games have gone over the total in 29 of 73 chances this season, while Orioles games have gone under in 19 of their last 27 away outings, making the 9.5-run line a tight push between over and under.

BAL vs. NYY
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: J, Chisholm over 0.5 Total Bases.

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Baltimore vs New York Yankees Prediction & Odds:
Free MLB Betting Insights for 6/22/25

Sunday’s finale between the Baltimore Orioles and the New York Yankees at Yankee Stadium promises to be a tightly contested showdown between two AL East clubs riding the momentum of strong June performances and eyeing critical wins as the playoff picture begins to sharpen. The Yankees will send right-hander Will Warren to the mound in what is expected to be a pressure-filled outing as he faces an Orioles team that has gone 10–5 in June and shown flashes of offensive brilliance, particularly from the young trio of Gunnar Henderson, Jackson Holliday, and Adley Rutschman, who’ve carried much of Baltimore’s run production lately. Warren will be backed by a Yankees bullpen that includes late-inning options such as Kirby Yates, Luke Weaver, and Devin Williams, who returned just in time to fortify one of the league’s better relief units, which has played a critical role in New York’s recent 9–1 stretch over their last ten games. Opposing Warren will be righty Dean Kremer for Baltimore, a pitcher with a 4.80 ERA and a reputation for battling deep into games, but who must avoid giving up early runs against a Yankee offense that, despite being quiet this weekend, still features Aaron Judge, Juan Soto, and Gleyber Torres—players capable of flipping a game’s momentum with one swing. The key for Kremer will be limiting long counts and avoiding big innings, especially early, to give the Orioles a chance to stay competitive late.

Defensively, the Yankees have a significant edge, with consistent execution across the field helping them avoid the miscues that have plagued the Orioles at times, particularly during tight late-game situations. The total for the game is set at 9.5 runs, reflecting expectations of moderate scoring, and both teams have shown a tendency to either hit the under in low-scoring, bullpen-dominated contests or the over when their lineups break out, which makes the total difficult to call and puts added emphasis on the effectiveness of the starting pitchers. Baltimore’s ability to grind at-bats and manufacture runs has improved during June, but they still tend to rely heavily on their top four hitters for offense, and any dip in their production leaves the bottom of the order vulnerable against dominant bullpen arms. If Warren can pitch effectively into the fifth or sixth inning and the Yankees’ bats come alive early, this matchup could tilt decisively toward New York, but if Kremer keeps the game close and Baltimore capitalizes on early scoring opportunities, the visitors have enough firepower to challenge even a deep Yankees bullpen. Ultimately, the matchup feels like a potential 5–4 or 6–4 Yankees win, but it remains close enough that one defensive miscue or bullpen slip could change the script entirely, especially with both teams capable of putting up runs in bunches. With division stakes looming larger, and both teams fighting for position, expect a playoff-like atmosphere and sharp execution in what should be one of the weekend’s most compelling matchups.

Baltimore Orioles MLB Preview

The Baltimore Orioles enter Sunday’s series finale at Yankee Stadium with quiet confidence and a noticeable June turnaround, winning 10 of their last 15 games while steadily climbing back toward .500 and finding offensive rhythm behind a young and explosive core. Right-hander Dean Kremer will take the mound for Baltimore, and while his 4.80 ERA underscores a season of ups and downs, his ability to generate weak contact and occasionally dominate with his cutter and curveball gives him a chance to quiet even a dangerous Yankees lineup when he’s in rhythm. Kremer will need to be sharp early and avoid falling behind in counts, especially against the top half of New York’s order where the likes of Aaron Judge and Juan Soto can capitalize quickly on mistakes, and keeping the Yankees in the park through the first five innings will be vital to the Orioles’ chances. Offensively, Baltimore is anchored by Gunnar Henderson, who has continued to shine in clutch moments, while Adley Rutschman’s leadership and approach at the plate have helped set the tone for a lineup that is young but dangerous when locked in. Jackson Holliday adds excitement and spark from the leadoff spot, and players like Anthony Santander and Ryan Mountcastle can provide pop if the top of the order gets on base. However, consistency remains a concern for the Orioles, particularly in the bottom half of the lineup where offensive production can disappear for stretches, forcing the stars to carry a heavy load in tight games.

Defensively, Baltimore has struggled with untimely errors, and their fielding will need to be precise against a Yankees team that capitalizes on every extra opportunity; if Kremer can pitch to contact and let the defense work behind him without miscues, they’ll have a strong shot at keeping the game within reach. The Orioles’ bullpen, though not elite, has had flashes of reliability, especially from Yennier Cano and Danny Coulombe, but extended innings from Kremer will be crucial in keeping the relievers from being overexposed to New York’s patient and powerful lineup. ATS-wise, Baltimore enters the day 32–42 overall but has played tight games at Yankee Stadium, and a 5–8 ATS mark this weekend shows their capacity to hang with better teams despite often being underdogs. If they can jump on Yankees starter Will Warren early, build a lead through the middle innings, and avoid bullpen breakdowns, Baltimore could steal a close win and return home with series momentum. But if Kremer falters or the defense reverts to its inconsistent habits, the Orioles could find themselves chasing runs against a deeper lineup and bullpen than they can match late. A best-case scenario for Baltimore looks like a 5–4 or 6–5 win with key hits in the sixth and seventh innings, but more likely, they’ll need to play flawless baseball just to stay in it against a confident and rested Yankees squad.

Saturday’s showdown at Yankee Stadium pits the Baltimore Orioles against the New York Yankees in a pivotal late-June clash. First pitch is set for 11:35 a.m. ET on June 22, 2025. New York opens as a strong home favorite, with the total around 9.5 runs—a line that suggests a balanced, moderately high-scoring game. Baltimore vs New York Yankees AI Prediction: Free MLB Betting Insights for Jun 22. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

New York Yankees Yankees MLB Preview

The New York Yankees come into Sunday’s home finale against the Baltimore Orioles with confidence and momentum, having won nine of their last ten games and continuing to find ways to dominate opponents with elite pitching, deep bullpen support, and a lineup brimming with star power that’s always one breakout away from a big offensive explosion. They’ll hand the ball to right-hander Will Warren, who steps into a high-pressure environment against a red-hot Baltimore team riding a strong June stretch, and although Warren doesn’t bring ace-level pedigree, he’s shown promise in limiting walks and inducing ground balls—traits that will serve him well against a young, aggressive Orioles lineup. The Yankees’ offensive unit remains one of the most dangerous in baseball despite some recent slumps, with Aaron Judge leading the charge, supported by Juan Soto, Gleyber Torres, and Giancarlo Stanton, giving the team a lineup that can strike quickly and pile up crooked numbers with minimal warning. Even when the offense doesn’t click immediately, the Yankees have proven adept at working pitch counts and exhausting starters, which could be especially important against Dean Kremer, a pitcher with inconsistent command and a tendency to unravel once the top of the order cycles back through a second time. Defensively, New York continues to impress with crisp execution, clean infield work, and outfield arms that discourage aggressive base running, all of which combine to reduce the likelihood of extended innings due to errors or lapses in coverage.

Their bullpen is once again a strength, with Kirby Yates anchoring the ninth, Devin Williams back from injury providing setup relief, and Luke Weaver capable of covering multi-inning stints when needed—an especially important asset should Warren need early relief. New York’s home ATS record has been trending upward with a 6–4 mark in their last ten, and as heavy favorites they’ve gone 13–8 when listed at –189 or better, indicating that they’ve done a solid job covering even with high expectations. Against a Baltimore team that’s been playing well but remains vulnerable to fielding issues and back-end bullpen inconsistency, the Yankees are well positioned to control the tempo of the game early, especially if they can get to Kremer in the first few innings and force the Orioles to dip into middle relief before the sixth. The total sits around 9.5 runs, and while that suggests moderate scoring, the Yankees’ combination of power, patience, and late-game poise could push this one over if their bats heat up and they get even five solid innings out of Warren. A 5–3 or 6–4 New York win feels like the most likely outcome based on current form and matchup dynamics, and if the Yankees play their brand of clean, opportunistic baseball in front of their home crowd, they should walk away with a series win and continue to build momentum as one of the American League’s most dangerous postseason contenders.

Baltimore vs. New York Yankees Prop Picks (AI)

AI algorithm Remi is pouring through tons of datapoints on each line. In fact, anytime the Orioles and Yankees play there’s always several intriguing angles to key in on. Not to mention games played at Yankee Stadium in Jun can often follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: J, Chisholm over 0.5 Total Bases.

Baltimore vs. New York Yankees Prediction (AI)

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Remi, our AI sports algorithm, has been pouring over exorbitant amounts of data from every past game between the Orioles and Yankees and using recursive machine learning and cutting-edge AI to analyze the data to a single cover probability.

Oddly enough, we’ve seen the AI has been most fixated on the growing weight knucklehead sportsbettors regularly put on player performance factors between a Orioles team going up against a possibly strong Yankees team. Trends look to say the true game analytics might reflect a strong lean against one Vegas line specifically.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI Baltimore vs New York Yankees picks, computer picks Orioles vs Yankees, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
MLB 9/26 DET@BOS UNLOCK THIS PICK 5 EXECUTIVE Locked EXECUTIVE
MLB 9/26 BAL@NYY UNLOCK THIS PICK 4 INTEL Locked INTEL
MLB 9/26 ARI@SD UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
MLB 9/26 NYM@MIA UNLOCK THIS PICK 1 INTEL Locked INTEL
MLB 9/26 NYM@MIA GET FREE PICK NOW 1
MLB 9/26 COL@SF UNLOCK THIS PICK 0 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

Orioles Betting Trends

Baltimore sits at 32–42 ATS for the season, but they’ve gone 5–8 ATS at Yankee Stadium this weekend and have covered five of their last ten games, showing resilience even as underdogs.

Yankees Betting Trends

New York is 34–40 ATS overall and 6–4 in their last ten games. As favorites of –189 or better, they’re 13–8 this season and have covered in eight of their last ten starts.

Orioles vs. Yankees Matchup Trends

Yankees games have gone over the total in 29 of 73 chances this season, while Orioles games have gone under in 19 of their last 27 away outings, making the 9.5-run line a tight push between over and under.

Baltimore vs. New York Yankees Game Info

Baltimore vs New York Yankees starts on June 22, 2025 at 11:35 AM.

Spread: New York Yankees -1.5
Moneyline: Baltimore +160, New York Yankees -193
Over/Under: 9.5

Baltimore: (33-43)  |  New York Yankees: (44-32)

Remi's searched hard and found the best prop for this matchup: J, Chisholm over 0.5 Total Bases.. Prices move—always shop for the best number.

Yankees games have gone over the total in 29 of 73 chances this season, while Orioles games have gone under in 19 of their last 27 away outings, making the 9.5-run line a tight push between over and under.

BAL trend: Baltimore sits at 32–42 ATS for the season, but they’ve gone 5–8 ATS at Yankee Stadium this weekend and have covered five of their last ten games, showing resilience even as underdogs.

NYY trend: New York is 34–40 ATS overall and 6–4 in their last ten games. As favorites of –189 or better, they’re 13–8 this season and have covered in eight of their last ten starts.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

Baltimore vs. New York Yankees Odds

Remi is pouring through loads of data on each team. In fact, anytime the Baltimore vs New York Yankees trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme altitude can often follow normal, predictable patterns.

Baltimore vs New York Yankees Opening Odds

BAL Moneyline: +160
NYY Moneyline: -193
BAL Spread: +1.5
NYY Spread: -1.5
Over/Under: 9.5

Baltimore vs New York Yankees Live Odds

Games PTS ML SPR O/U
Sep 27, 2025 1:06PM EDT
Baltimore Orioles
New York Yankees
9/27/25 1:06PM
Orioles
Yankees
+194
-235
+1.5 (-105)
-1.5 (-114)
O 8.5 (-122)
U 8.5 (+100)
Sep 27, 2025 2:21PM EDT
St Louis Cardinals
Chicago Cubs
9/27/25 2:21PM
Cardinals
Cubs
 
-168
 
-1.5 (+118)
O 9 (-122)
U 9 (+100)
Sep 27, 2025 3:09PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/27/25 3:09PM
Rays
Blue Jays
+132
-156
+1.5 (-154)
-1.5 (+128)
O 8.5 (-106)
U 8.5 (-114)
Sep 27, 2025 4:06PM EDT
Chicago White Sox
Washington Nationals
9/27/25 4:06PM
White Sox
Nationals
+102
-120
-1.5 (+162)
+1.5 (-196)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 4:06PM EDT
Colorado Rockies
San Francisco Giants
9/27/25 4:06PM
Rockies
Giants
+198
-240
+1.5 (-110)
-1.5 (-110)
O 8 (-108)
U 8 (-112)
Sep 27, 2025 4:11PM EDT
New York Mets
Miami Marlins
9/27/25 4:11PM
Mets
Marlins
-124
+106
-1.5 (+130)
+1.5 (-156)
O 8.5 (-112)
U 8.5 (-108)
Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
+177
-197
+1.5 (-118)
-1.5 (-102)
O 8.5 (-118)
U 8.5 (-102)
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
+128
-152
+1.5 (-178)
-1.5 (+146)
O 7.5 (-120)
U 7.5 (-102)
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
+143
-158
+1.5 (-150)
-1.5 (+130)
O 8.5 (+100)
U 8.5 (-120)
Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
+132
-156
+1.5 (-172)
-1.5 (+142)
O 7 (-120)
U 7 (-102)
Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
+120
-132
+1.5 (-180)
-1.5 (+157)
O 7.5 (-115)
U 7.5 (-105)
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
+102
-120
+1.5 (-215)
-1.5 (+180)
O 7.5 (-110)
U 7.5 (-110)
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
+104
-115
+1.5 (-185)
-1.5 (+161)
O 10 (-110)
U 10 (-110)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Baltimore Orioles vs. New York Yankees Yankees on June 22, 2025 at Yankee Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS
CIN@ARI KEBRYAN HAYES STRIKEOUTS UNDER 0.5 56.2% 6 WIN
LAD@SD SD +110 50.9% 6 WIN