Diamondbacks vs. Rockies
Prediction, Odds & Props
Jun 22 | MLB AI Picks

Updated: 2025-06-20T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Arizona Diamondbacks visit Coors Field to close out their series against the Colorado Rockies on June 22, 2025, with first pitch scheduled for 3:10 p.m. ET. Arizona is a strong favorite (‑200 ML, ‑1.5 run line), while the total is set high at 12.5 runs—reflecting Coors Field’s hitter-friendly reputation and expectations for offense.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Jun 22, 2025

Start Time: 3:10 PM EST​

Venue: Coors Field​

Rockies Record: (17-60)

Diamondbacks Record: (39-37)

OPENING ODDS

ARI Moneyline: -204

COL Moneyline: +168

ARI Spread: -1.5

COL Spread: +1.5

Over/Under: 12.5

ARI
Betting Trends

  • Arizona has been sharp as a favorite, covering in 7 of their last 10 games when favored, and their ATS record stands at a solid 7–3 in that span.

COL
Betting Trends

  • Colorado has struggled overall, with a dismal 9–43 record, but they’ve been slightly better as home underdogs (+165 or worse), with occasional ATS value despite the losses.

MATCHUP TRENDS

  • Six of Arizona’s last 10 games have gone over the total, including recent high-scoring affairs, while Coors Field games often exceed the 12.5 line due to thin air and offensive output—setting the stage for a potential over play in this matchup.

ARI vs. COL
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: C. Carroll under 14.5 Fantasy Score.

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Arizona vs Colorado Prediction & Odds:
Free MLB Betting Insights for 6/22/25

Sunday’s series finale between the Arizona Diamondbacks and the Colorado Rockies at Coors Field offers one of the most lopsided matchups on paper in the National League, as Arizona continues to push for playoff positioning while Colorado endures one of the league’s worst records. The Diamondbacks have been solid as favorites recently, covering seven of their last ten games when favored, and they’ll enter this contest behind probable starter Brandon Pfaadt, who carries an 8–4 record despite a 5.26 ERA, showcasing a repertoire built on control, late movement, and occasional strikeout bursts that should play reasonably well even in the altitude of Denver. Pfaadt’s key will be staying ahead in counts and avoiding the heart of the Rockies’ order, which has shown flashes of power but remains largely inconsistent and strikeout-prone. Arizona’s lineup, however, has consistently overwhelmed underwhelming pitching, and with the likes of Corbin Carroll, Ketel Marte, Josh Naylor, and Eugenio Suárez pacing the offense, the D-backs are well-equipped to pile up crooked numbers early, especially against Colorado’s struggling starter Antonio Senzatela.

The Rockies’ right-hander has a 2–10 record with a 6.72 ERA and a low strikeout rate, which is a dangerous combination in a venue like Coors Field that punishes mistakes and inflates run production. If Arizona’s bats are patient and make Senzatela work deep into counts, it could force Colorado’s overworked and underperforming bullpen into action by the fourth or fifth inning, where the game could truly get out of hand. Defensively, the Rockies have shown lapses, particularly in turning double plays and limiting extra bases, which only further aids Arizona’s game plan of staying aggressive and capitalizing on any miscues. Coors Field also inflates the total to a projected 12.5 runs, and with both teams leaning toward high-scoring outcomes in recent weeks—especially in this series—it’s fair to expect fireworks. From a betting perspective, the over remains appealing, but so does a Diamondbacks cover on the run line given their performance against subpar pitching and Colorado’s inability to hold leads or compete beyond the first few innings. If Pfaadt can keep the ball in the yard and Arizona’s offense continues its trend of early scoring, the game could tilt quickly toward the visitors, resulting in something like an 8–5 or 9–6 victory. However, if Colorado manages a rare offensive surge early and the Diamondbacks struggle with control or strand runners, the Rockies might keep it close—but their path to victory is narrow, and it hinges on almost flawless execution. All signs point to a high-scoring contest dominated by Arizona’s more complete roster, deeper bullpen, and playoff urgency, while Colorado continues to play catch-up both on the scoreboard and in their rebuild.

Arizona Diamondbacks MLB Preview

The Arizona Diamondbacks enter Sunday’s series finale at Coors Field with confidence and momentum, aiming to close out a strong stretch of play and take full advantage of a struggling Rockies squad. With a 7–3 record in their last ten games as favorites and a lineup that has begun firing on all cylinders, the Diamondbacks find themselves in prime position to control the narrative from the opening pitch. Brandon Pfaadt will take the mound, bringing with him an 8–4 record and a 5.26 ERA that reflects both moments of dominance and occasional inconsistency, though his pitch-to-contact style could work well if he maintains his command and limits free passes. The biggest key for Pfaadt will be avoiding elevated fastballs in the thin Denver air, where mistakes turn into long home runs, especially against aggressive lineups like Colorado’s. Offensively, Arizona has relied on a dynamic mix of speed, power, and clutch hitting, with Corbin Carroll and Ketel Marte setting the table while Josh Naylor and Eugenio Suárez provide the muscle in the middle of the order. Their ability to strike early and force pressure on opposing pitchers has served them well all season, especially against soft-tossing starters like Antonio Senzatela, who has struggled to miss bats and pitch deep into games.

Arizona’s bench also provides meaningful depth, with players like Gabriel Moreno and Jake McCarthy capable of contributing late-inning offense or speed on the basepaths. The Diamondbacks’ bullpen, bolstered by the presence of Merrill Kelly and Zac Gallen in the rotation and a dependable mix of setup men and closers, gives manager Torey Lovullo flexibility in late-game decisions, particularly when nursing a narrow lead or preserving a multi-run cushion. From a situational and betting perspective, Arizona has shown that they not only win games they’re favored in, but often do so comfortably, which makes their run-line performance noteworthy heading into this matchup. Coors Field’s offensive environment should only amplify their advantages, as Arizona’s lineup is less reliant on the home run and more capable of stringing together productive innings through doubles, walks, and hustle. With Pfaadt on the mound and the offense clicking, the Diamondbacks have a clear opportunity to break this game open early and force Colorado to play from behind, a position the Rockies have not handled well this season. If the D-backs avoid defensive lapses and execute their early-inning game plan, a final score in the neighborhood of 8–5 or 9–6 seems well within reach, especially if they can chase Senzatela early and get into a vulnerable bullpen. Ultimately, Arizona’s blend of starting pitching, high-leverage experience, and lineup balance gives them a distinct edge on Sunday, and if they stay disciplined and focused, they should finish this series with a statement win and additional momentum heading into their next matchup.

The Arizona Diamondbacks visit Coors Field to close out their series against the Colorado Rockies on June 22, 2025, with first pitch scheduled for 3:10 p.m. ET. Arizona is a strong favorite (‑200 ML, ‑1.5 run line), while the total is set high at 12.5 runs—reflecting Coors Field’s hitter-friendly reputation and expectations for offense. Arizona vs Colorado AI Prediction: Free MLB Betting Insights for Jun 22. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Colorado Rockies MLB Preview

The Colorado Rockies return to Coors Field for Sunday’s finale against the Arizona Diamondbacks hoping to salvage a win in what has been a painfully one-sided season, as their 17–59 record speaks to deep struggles in both pitching and offensive execution. Antonio Senzatela is expected to get the start, and while the veteran right-hander offers experience and pitch-to-contact tendencies suited for high-altitude games, his 2–10 record and 6.72 ERA underscore how frequently things have gone wrong when he’s on the mound, particularly against disciplined, power-laden lineups like Arizona’s. Senzatela’s success will depend entirely on his ability to generate early-count groundballs, avoid elevated pitches, and survive the first two trips through the order, where the Diamondbacks thrive with gap-to-gap power and aggressive base running. Offensively, the Rockies are built around flashes of power from Hunter Goodman and Jordan Beck, while Ryan McMahon continues to lead the team in OBP and clutch situations, but beyond those names, there is a noticeable drop in consistency and run-producing capability. Colorado has been unable to string together multi-run innings, often relying on solo homers or opponents’ mistakes to generate offense, a strategy that doesn’t work when trailing by multiple runs or facing bullpens that can lock down late innings.

The team’s bullpen remains one of the least reliable in the majors, frequently overused due to short starts and yielding high ERAs across the board, leaving manager Bud Black with few trustworthy options in high-leverage spots. Defensively, the Rockies have not helped themselves either, ranking near the bottom of the league in fielding percentage and often extending innings due to poor infield execution and outfield miscues, especially in tricky conditions at Coors Field. From a betting and ATS standpoint, Colorado has provided some limited value at home when extremely undervalued, but their 9–43 overall record and inability to cover consistently—even when catching large plus-money run lines—highlights just how difficult it has been for them to remain competitive beyond the third or fourth inning in most games. If the Rockies have any chance to pull off an upset, it will require an early offensive outburst combined with a rare quality start from Senzatela that stretches beyond five innings, plus a bullpen that doesn’t collapse late, a scenario that’s happened only a handful of times all season. Still, the unpredictable nature of Coors Field means a high-scoring slugfest could unfold if Arizona’s pitchers lose command and Colorado’s bats catch fire, and in that best-case scenario, the Rockies could grind out something like a 9–7 win. Realistically, though, their margin for error is razor thin, and they’ll need contributions from top to bottom—both offensively and defensively—to stand a chance against one of the NL’s more balanced lineups. Sunday’s matchup may provide a window into how Colorado evaluates its young core, but in terms of outcome, the Rockies are massive underdogs needing their best game of the month just to stay within striking distance.

Arizona vs. Colorado Prop Picks (AI)

AI algorithm Remi is pouring through loads of stats on each line. In fact, anytime the Diamondbacks and Rockies play there’s always several intriguing observations to key in on. Not to mention games played at Coors Field in Jun almost always follow normal, predictable patterns.
Remi's searched hard and found the best prop for this matchup: C. Carroll under 14.5 Fantasy Score.

Arizona vs. Colorado Prediction (AI)

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Remi, our AI sports wizard, has been pouring over mountains of data from every facet between the Diamondbacks and Rockies and using recursive machine learning and impressive AI to crunch the data to a single cover probability.

Interestingly enough, the data has been most keyed in on the unproportionally assigned factor emotional bettors tend to put on Colorado’s strength factors between a Diamondbacks team going up against a possibly rested Rockies team. We’ve found the true game analytics might reflect a slight lean against one Vegas line in particular.

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Below is our current AI Arizona vs Colorado picks, computer picks Diamondbacks vs Rockies, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
MLB 9/26 DET@BOS UNLOCK THIS PICK 5 EXECUTIVE Locked EXECUTIVE
MLB 9/26 BAL@NYY UNLOCK THIS PICK 4 INTEL Locked INTEL
MLB 9/26 ARI@SD UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
MLB 9/26 NYM@MIA UNLOCK THIS PICK 1 INTEL Locked INTEL
MLB 9/26 NYM@MIA GET FREE PICK NOW 1
MLB 9/26 COL@SF UNLOCK THIS PICK 0 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

Diamondbacks Betting Trends

Arizona has been sharp as a favorite, covering in 7 of their last 10 games when favored, and their ATS record stands at a solid 7–3 in that span.

Rockies Betting Trends

Colorado has struggled overall, with a dismal 9–43 record, but they’ve been slightly better as home underdogs (+165 or worse), with occasional ATS value despite the losses.

Diamondbacks vs. Rockies Matchup Trends

Six of Arizona’s last 10 games have gone over the total, including recent high-scoring affairs, while Coors Field games often exceed the 12.5 line due to thin air and offensive output—setting the stage for a potential over play in this matchup.

Arizona vs. Colorado Game Info

Arizona vs Colorado starts on June 22, 2025 at 3:10 PM EST.

Spread: Colorado +1.5
Moneyline: Arizona -204, Colorado +168
Over/Under: 12.5

Arizona: (39-37)  |  Colorado: (17-60)

Remi's searched hard and found the best prop for this matchup: C. Carroll under 14.5 Fantasy Score.. Prices move—always shop for the best number.

Six of Arizona’s last 10 games have gone over the total, including recent high-scoring affairs, while Coors Field games often exceed the 12.5 line due to thin air and offensive output—setting the stage for a potential over play in this matchup.

ARI trend: Arizona has been sharp as a favorite, covering in 7 of their last 10 games when favored, and their ATS record stands at a solid 7–3 in that span.

COL trend: Colorado has struggled overall, with a dismal 9–43 record, but they’ve been slightly better as home underdogs (+165 or worse), with occasional ATS value despite the losses.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

Arizona vs. Colorado Odds

AI algorithm Remi is pouring through mountains of data on each line. In fact, anytime the Arizona vs Colorado trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme temps rarely follow normal, predictable betting trends.

Arizona vs Colorado Opening Odds

ARI Moneyline: -204
COL Moneyline: +168
ARI Spread: -1.5
COL Spread: +1.5
Over/Under: 12.5

Arizona vs Colorado Live Odds

Games PTS ML SPR O/U
Sep 27, 2025 1:06PM EDT
Baltimore Orioles
New York Yankees
9/27/25 1:06PM
Orioles
Yankees
+194
-235
+1.5 (-105)
-1.5 (-114)
O 8.5 (-122)
U 8.5 (+100)
Sep 27, 2025 2:21PM EDT
St Louis Cardinals
Chicago Cubs
9/27/25 2:21PM
Cardinals
Cubs
 
-168
 
-1.5 (+118)
O 9 (-122)
U 9 (+100)
Sep 27, 2025 3:09PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/27/25 3:09PM
Rays
Blue Jays
+132
-156
+1.5 (-154)
-1.5 (+128)
O 8.5 (-106)
U 8.5 (-114)
Sep 27, 2025 4:06PM EDT
Chicago White Sox
Washington Nationals
9/27/25 4:06PM
White Sox
Nationals
+102
-120
-1.5 (+162)
+1.5 (-196)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 4:06PM EDT
Colorado Rockies
San Francisco Giants
9/27/25 4:06PM
Rockies
Giants
+198
-240
+1.5 (-110)
-1.5 (-110)
O 8 (-108)
U 8 (-112)
Sep 27, 2025 4:11PM EDT
New York Mets
Miami Marlins
9/27/25 4:11PM
Mets
Marlins
-124
+106
-1.5 (+130)
+1.5 (-156)
O 8.5 (-112)
U 8.5 (-108)
Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
+177
-197
+1.5 (-118)
-1.5 (-102)
O 8.5 (-118)
U 8.5 (-102)
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
+128
-152
+1.5 (-178)
-1.5 (+146)
O 7.5 (-120)
U 7.5 (-102)
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
+143
-158
+1.5 (-150)
-1.5 (+130)
O 8.5 (+100)
U 8.5 (-120)
Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
+132
-156
+1.5 (-172)
-1.5 (+142)
O 7 (-120)
U 7 (-102)
Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
+120
-132
+1.5 (-180)
-1.5 (+157)
O 7.5 (-115)
U 7.5 (-105)
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
+102
-120
+1.5 (-215)
-1.5 (+180)
O 7.5 (-110)
U 7.5 (-110)
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
+104
-115
+1.5 (-185)
-1.5 (+161)
O 10 (-110)
U 10 (-110)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Arizona Diamondbacks vs. Colorado Rockies on June 22, 2025 at Coors Field.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS
CIN@ARI KEBRYAN HAYES STRIKEOUTS UNDER 0.5 56.2% 6 WIN
LAD@SD SD +110 50.9% 6 WIN