White Sox vs. Blue Jays
Prediction, Odds & Props
Jun 21 | MLB AI Picks
Updated: 2025-06-19T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The Chicago White Sox will visit Rogers Centre to take on the Toronto Blue Jays on June 21, 2025 in a matchup with first pitch set for 3:07 p.m. ET. Toronto enters as a strong favorite with a −213 moneyline and an 8.5-run total, pointing to a game expected to lean toward the over.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Jun 21, 2025
Start Time: 3:07 PM EST
Venue: Rogers Centre
Blue Jays Record: (40-35)
White Sox Record: (24-52)
OPENING ODDS
CHW Moneyline: +176
TOR Moneyline: -213
CHW Spread: +1.5
TOR Spread: -1.5
Over/Under: 8.5
CHW
Betting Trends
- The White Sox are a middling 5–5 ATS over their last 10 games, though they’ve been more competitive as underdogs, posting a 6–4 ATS mark in their recent 10 games against the spread.
TOR
Betting Trends
- The Blue Jays are 4–6 ATS over their past 10 games and have been favored in four of those but only managed a 2–2 record when priced as favorites.
MATCHUP TRENDS
- Toronto’s recent games have leaned over the total in 5 of the last 10, while Chicago’s underdog games have stayed under 6 of 10—suggesting a tilt toward offensive production, but also room for a tighter scoring pace.
CHW vs. TOR
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: K. Teel over 0.5 Hits+Runs+RBI.
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Chicago White Sox vs Toronto Prediction & Odds:
Free MLB Betting Insights for 6/21/25
Offensively, the Blue Jays continue to lean on Vladimir Guerrero Jr. and Bo Bichette, both of whom have delivered middle-of-the-lineup production despite Toronto’s recent offensive inconsistencies. Alejandro Kirk has emerged as a steady presence behind the plate and in the lower part of the lineup, batting over .310 and giving Toronto valuable depth. The battle will likely be decided in the middle innings—if Berríos can get through five with limited damage, the Blue Jays’ bullpen has the edge in experience and control, anchored by arms like Chad Green and Jeff Hoffman. Chicago, meanwhile, has a more experimental bullpen due to recent injuries, and could be vulnerable if Civale doesn’t last deep into the game. Saturday’s total is set at 8.5 runs, which reflects moderate expectations from oddsmakers in terms of scoring, though both lineups have the capability to exceed that if the game opens up early. The White Sox have been surprisingly effective against the spread recently, going 6–4 ATS in their last 10 games despite their poor overall record, while Toronto is just 4–6 ATS over the same span and has failed to cover in some games where they were heavy favorites. If the White Sox can apply early pressure and get on base against Berríos, they could make things interesting, particularly if they build a cushion before the bullpen becomes a factor. However, if Toronto’s veteran arms settle in and the offense capitalizes on Civale’s occasional control lapses, the Blue Jays should be able to retake control of the series with a 6–4 or 7–3 type of win. Still, Friday’s upset serves as a reminder that even in a matchup of playoff hopefuls versus bottom-dwellers, baseball always leaves room for surprises.
bats were boomin' pic.twitter.com/6SqcRixFO3
— Chicago White Sox (@whitesox) June 21, 2025
Chicago White Sox White Sox MLB Preview
The Chicago White Sox enter Saturday’s contest against the Toronto Blue Jays with one of their most encouraging wins in recent memory under their belts, having taken Friday’s series opener 7–1 behind timely hitting, solid pitching, and a rare clean defensive effort. Though they still sit at a dismal 23–52 on the season, Friday’s win was a bright spot in what has otherwise been a developmental year focused more on future pieces than short-term results. Manager Will Venable has embraced the youth movement and leaned into aggressive base running, situational hitting, and giving reps to prospects trying to carve out roles in the big leagues. The offense is built around flashes of power and speed, anchored by Luis Robert Jr., who showcased his five-tool talent in the opener, and bolstered by the recent production of Miguel Vargas, whose blend of gap power and improved patience at the plate has been critical. Andrew Benintendi, one of the few veterans with playoff experience, continues to provide steady contact and leadership, while players like Gavin Sheets and Chase Meidroth have quietly added spark with clutch at-bats. On the mound for Saturday’s matchup is Aaron Civale, whose 1–3 record and 4.67 ERA reflect his struggles with consistency and command, though his ability to induce ground balls and work through lineups efficiently when his cutter is sharp makes him a viable option against a powerful Blue Jays lineup.
Civale’s success will depend on avoiding long innings and keeping Toronto’s top-of-the-order hitters from sparking early rallies, as he’s not equipped to pitch from behind or recover from big innings. The bullpen, already thin due to injuries to Cam Booser and Davis Martin, will again rely on inexperienced arms like Wikelman Gonzalez and Jake Palisch, who both debuted in this series and held their own in Game 1. If Civale can navigate five or six innings, Venable will have the option to turn the game over to Martín Pérez or Brandon Eisert for bridge innings, though this pen remains untested in high-leverage, late-game road environments. Defensively, Chicago must maintain the clean play they exhibited Friday—avoiding miscues that could extend innings or allow Toronto’s hitters to reset the count—and their improved infield communication will be vital against a lineup that pressures defenders with hard contact and aggressive base running. The White Sox are 6–4 against the spread in their last 10 games and have covered multiple times as large underdogs, including at similar odds as Saturday’s +176 mark, which shows they’ve been more competitive than their record suggests when expectations are low. For Chicago to keep momentum, they’ll need to score early, control the tempo through Civale’s pace, and avoid bullpen meltdowns. A second consecutive upset win is certainly possible, especially if the bats can chase Berríos by the fourth or fifth and capitalize on any bullpen inefficiencies. Though they remain long shots in every measurable category, this young and hungry White Sox group has proven they can disrupt more polished teams on any given day with hustle, timely hitting, and just enough pitching to hold the line.

Credit: USA TODAY/IMAGN
Toronto Blue Jays MLB Preview
The Toronto Blue Jays approach Saturday’s matchup against the Chicago White Sox with a mix of urgency and expectation, aiming to bounce back from a disappointing 7–1 loss in Friday’s opener and reassert control over a series they were favored to dominate. With a 40–35 overall record and a strong 22–13 mark at home, Toronto remains firmly in the American League playoff picture but can’t afford to let down against one of the league’s weakest teams, especially at Rogers Centre, where they’ve thrived this season. José Berríos will take the mound looking to steady the ship; while his 2–3 record doesn’t reflect dominance, his 3.81 ERA and ability to pitch deep into games make him a crucial piece of Toronto’s rotation, especially with Kevin Gausman managing rest and Max Scherzer being gradually eased into action. Berríos thrives when he’s locating his fastball early and using his slurve to change eye levels, and against a young, aggressive White Sox lineup, efficiency and tempo will be key. The Blue Jays’ offense has had its moments of brilliance this season but also stretches of inconsistency, and they’ll need to be locked in on Saturday to avoid consecutive letdowns.
Vladimir Guerrero Jr. (.282, 9 HR, 43 RBI) and Bo Bichette (10 HR, 45 RBI) remain the cornerstones of this lineup, combining power with contact skills, and they’ll be tasked with sparking an early rally against Aaron Civale, a finesse pitcher who Toronto should be able to hit if they stay patient. Alejandro Kirk has emerged as a surprising standout this month, providing consistent contact from the lower half of the order and helping extend innings with smart plate appearances. George Springer and Daulton Varsho continue to provide secondary power and defensive value, and the lineup as a whole is designed to wear down opposing starters with deep at-bats and selective aggression. Defensively, the Blue Jays are fundamentally sound, and they’ll need to be sharp against a White Sox team that plays with urgency and pressure, especially on the basepaths. The bullpen will also be a factor—Toronto’s relief corps, led by Chad Green, Jeff Hoffman, and Mason Fluharty, has the stuff to shut down games but has shown some volatility in recent weeks. With Berríos likely to go six innings, the bridge to the late innings will be critical, and manager John Schneider may not hesitate to go to his bullpen early if the game starts slipping. Toronto has gone just 4–6 against the spread over their last 10 games and hasn’t consistently covered as a sizable favorite, which places more emphasis on execution and staying focused for nine full innings. With the White Sox playing looser and more opportunistic baseball, the Blue Jays must establish control early, force Civale into high pitch counts, and capitalize on any defensive lapses. If they can execute their typical formula—quality start, timely power, and solid relief—they should be in position to even the series and regain momentum. Saturday’s outcome will come down to focus and composure; if Toronto plays to its potential, a 6–3 or 7–4 win feels well within reach.
— Toronto Blue Jays (@BlueJays) June 21, 2025
Chicago White Sox vs. Toronto Prop Picks (AI)
Chicago White Sox vs. Toronto Prediction (AI)

Remi, our AI sports wizard, has been pouring over tons of data from every facet between the White Sox and Blue Jays and using recursive machine learning and cutting-edge AI to boil down the data to a single cover probability.
The Algorithm has been most focused on the growing emphasis human bettors tend to put on player performance factors between a White Sox team going up against a possibly tired Blue Jays team. In reality, the true game analytics might reflect a strong lean against one Vegas line specifically.
Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.
Below is our current AI Chicago White Sox vs Toronto picks, computer picks White Sox vs Blue Jays, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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MLB | 9/26 | DET@BOS | UNLOCK THIS PICK | 5 |
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MLB | 9/26 | BAL@NYY | UNLOCK THIS PICK | 4 |
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MLB | 9/26 | ARI@SD | UNLOCK THIS PICK | 4 |
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MLB | 9/26 | NYM@MIA | UNLOCK THIS PICK | 1 |
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MLB | 9/26 | NYM@MIA | GET FREE PICK NOW | 1 | – | |
MLB | 9/26 | COL@SF | UNLOCK THIS PICK | 0 |
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.
White Sox Betting Trends
The White Sox are a middling 5–5 ATS over their last 10 games, though they’ve been more competitive as underdogs, posting a 6–4 ATS mark in their recent 10 games against the spread.
Blue Jays Betting Trends
The Blue Jays are 4–6 ATS over their past 10 games and have been favored in four of those but only managed a 2–2 record when priced as favorites.
White Sox vs. Blue Jays Matchup Trends
Toronto’s recent games have leaned over the total in 5 of the last 10, while Chicago’s underdog games have stayed under 6 of 10—suggesting a tilt toward offensive production, but also room for a tighter scoring pace.
Chicago White Sox vs. Toronto Game Info
What time does Chicago White Sox vs Toronto start on June 21, 2025?
Chicago White Sox vs Toronto starts on June 21, 2025 at 3:07 PM EST.
Where is Chicago White Sox vs Toronto being played?
Venue: Rogers Centre.
What are the opening odds for Chicago White Sox vs Toronto?
Spread: Toronto -1.5
Moneyline: Chicago White Sox +176, Toronto -213
Over/Under: 8.5
What are the records for Chicago White Sox vs Toronto?
Chicago White Sox: (24-52) | Toronto: (40-35)
What is the AI best bet for Chicago White Sox vs Toronto?
Remi's searched hard and found the best prop for this matchup: K. Teel over 0.5 Hits+Runs+RBI.. Prices move—always shop for the best number.
What are Chicago White Sox vs Toronto trending bets?
Toronto’s recent games have leaned over the total in 5 of the last 10, while Chicago’s underdog games have stayed under 6 of 10—suggesting a tilt toward offensive production, but also room for a tighter scoring pace.
What are Chicago White Sox trending bets?
CHW trend: The White Sox are a middling 5–5 ATS over their last 10 games, though they’ve been more competitive as underdogs, posting a 6–4 ATS mark in their recent 10 games against the spread.
What are Toronto trending bets?
TOR trend: The Blue Jays are 4–6 ATS over their past 10 games and have been favored in four of those but only managed a 2–2 record when priced as favorites.
Where can I find AI Picks for Chicago White Sox vs Toronto?
See our latest MLB picks and odds pages for 2025 to compare prices before you bet.
Chicago White Sox vs. Toronto Odds
AI algorithm Remi is pouring through mountains of data points on each line. In fact, anytime the Chicago White Sox vs Toronto trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme temps seemingly never follow normal, predictable betting trends.
Chicago White Sox vs Toronto Opening Odds
CHW Moneyline:
+176 TOR Moneyline: -213
CHW Spread: +1.5
TOR Spread: -1.5
Over/Under: 8.5
Chicago White Sox vs Toronto Live Odds
Games | PTS | ML | SPR | O/U | |
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Sep 27, 2025 1:06PM EDT
Baltimore Orioles
New York Yankees
9/27/25 1:06PM
Orioles
Yankees
|
–
–
|
+194
-235
|
+1.5 (-105)
-1.5 (-114)
|
O 8.5 (-122)
U 8.5 (+100)
|
|
Sep 27, 2025 2:21PM EDT
St Louis Cardinals
Chicago Cubs
9/27/25 2:21PM
Cardinals
Cubs
|
–
–
|
-168
|
-1.5 (+118)
|
O 9 (-122)
U 9 (+100)
|
|
Sep 27, 2025 3:09PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/27/25 3:09PM
Rays
Blue Jays
|
–
–
|
+132
-156
|
+1.5 (-154)
-1.5 (+128)
|
O 8.5 (-106)
U 8.5 (-114)
|
|
Sep 27, 2025 4:06PM EDT
Chicago White Sox
Washington Nationals
9/27/25 4:06PM
White Sox
Nationals
|
–
–
|
+102
-120
|
-1.5 (+162)
+1.5 (-196)
|
O 8.5 (-110)
U 8.5 (-110)
|
|
Sep 27, 2025 4:06PM EDT
Colorado Rockies
San Francisco Giants
9/27/25 4:06PM
Rockies
Giants
|
–
–
|
+198
-240
|
+1.5 (-110)
-1.5 (-110)
|
O 8 (-108)
U 8 (-112)
|
|
Sep 27, 2025 4:11PM EDT
New York Mets
Miami Marlins
9/27/25 4:11PM
Mets
Marlins
|
–
–
|
-124
+106
|
-1.5 (+130)
+1.5 (-156)
|
O 8.5 (-112)
U 8.5 (-108)
|
|
Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
|
–
–
|
+177
-197
|
+1.5 (-118)
-1.5 (-102)
|
O 8.5 (-118)
U 8.5 (-102)
|
|
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
|
–
–
|
+128
-152
|
+1.5 (-178)
-1.5 (+146)
|
O 7.5 (-120)
U 7.5 (-102)
|
|
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
|
–
–
|
+143
-158
|
+1.5 (-150)
-1.5 (+130)
|
O 8.5 (+100)
U 8.5 (-120)
|
|
Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
|
–
–
|
+132
-156
|
+1.5 (-172)
-1.5 (+142)
|
O 7 (-120)
U 7 (-102)
|
|
Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
|
–
–
|
+120
-132
|
+1.5 (-180)
-1.5 (+157)
|
O 7.5 (-115)
U 7.5 (-105)
|
|
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
|
–
–
|
+102
-120
|
+1.5 (-215)
-1.5 (+180)
|
O 7.5 (-110)
U 7.5 (-110)
|
|
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
|
–
–
|
+104
-115
|
+1.5 (-185)
-1.5 (+161)
|
O 10 (-110)
U 10 (-110)
|
MLB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Chicago White Sox White Sox vs. Toronto Blue Jays on June 21, 2025 at Rogers Centre.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
NYM@CHC | NYM -110 | 54.1% | 3 | WIN |
HOU@ATH | ATH +118 | 50.8% | 4 | WIN |
NYM@CHC | OVER 7 | 54.5% | 3 | WIN |
STL@SF | OVER 7.5 | 55.9% | 5 | LOSS |
KC@LAA | TYLER TOLBERT UNDER 1.5 BASES | 54.4% | 4 | WIN |
MIL@SD | UNDER 9 | 54.7% | 4 | WIN |
MIA@PHI | KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS | 53.3% | 3 | WIN |
WAS@NYM | OVER 8.5 | 56.1% | 6 | LOSS |
LAA@COL | COL +108 | 50.5% | 3 | WIN |
TOR@KC | UNDER 9 | 54.7% | 4 | LOSS |
SEA@KC | KC +1.5 | 62.3% | 5 | LOSS |
NYY@MIN | OVER 9 | 55.1% | 4 | WIN |
MIA@COL | OVER 10.5 | 55.0% | 4 | WIN |
MIA@COL | AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS | 54.3% | 4 | WIN |
SEA@KC | BOBBY WITT UNDER 0.5 SINGLES | 54.4% | 4 | LOSS |
PHI@LAD | LAD -113 | 54.7% | 4 | LOSS |
NYY@BOS | OVER 7.5 | 54.3% | 3 | WIN |
KC@PHI | PHI -130 | 58.3% | 4 | WIN |
LAD@SF | OVER 7.5 | 54.7% | 4 | LOSS |
NYM@PHI | PHI -122 | 55.6% | 4 | WIN |
KC@CLE | KC -104 | 52.0% | 3 | WIN |
CIN@SD | JAKE CRONEWORTH OVER 0.5 HITS | 53.1% | 3 | WIN |
WAS@MIA | MIA -123 | 55.2% | 4 | LOSS |
LAA@KC | UNDER 9.5 | 54.9% | 3 | WIN |
TEX@ARI | UNDER 9 | 54.2% | 4 | WIN |
SF@COL | UNDER 11.5 | 56.4% | 6 | LOSS |
SF@COL | RAFAEL DEVERS OVER 1.5 BASES | 56.1% | 6 | WIN |
MIA@WAS | WAS -110 | 54.4% | 4 | WIN |
NYM@DET | OVER 8.5 | 54.5% | 4 | WIN |
TEX@ARI | UNDER 9.5 | 56.4% | 6 | WIN |
TEX@ARI | ALEJANDRO OSUNA UNDER 1.5 BASES | 54.1% | 4 | LOSS |
ATL@CHC | CHC -116 | 55.1% | 3 | WIN |
PHI@MIL | OVER 8.5 | 55.0% | 3 | WIN |
ARI@LAD | SHOHEI OHTANI OVER 2.5 BASES | 54.2% | 4 | WIN |
SEA@CLE | CLE +1.5 | 57.2% | 3 | WIN |
CHC@SF | CHC -105 | 54.1% | 4 | LOSS |
NYY@CHW | RYAN MCMAHON OVER 0.5 BASES | 54.1% | 4 | WIN |
PHI@NYM | OVER 8.5 | 55.6% | 4 | LOSS |
LAA@TEX | LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS | 54.1% | 4 | LOSS |
KC@CHW | KC -109 | 54.2% | 4 | WIN |
SD@SEA | DYLAN CEASE OVER 16.5 OUTS | 53.9% | 3 | LOSS |
SD@SEA | UNDER 8.5 | 54.4% | 4 | LOSS |
MIN@TOR | JOE RYAN UNDER 2.5 EARNED RUNS | 54.1% | 4 | LOSS |
SF@MIL | MIL +100 | 54.0% | 6 | LOSS |
TOR@MIA | MIA +1.5 | 62.0% | 6 | WIN |
CHC@LAA | OVER 9.5 | 54.9% | 4 | LOSS |
BOS@NYY | CARLOS RODON UNDER 4.5 HITS ALLOWED | 54.2% | 4 | WIN |
KC@DET | DET -115 | 56.1% | 5 | WIN |
CHC@LAA | LAA +1.5 | 57.6% | 5 | LOSS |
CIN@ARI | KEBRYAN HAYES STRIKEOUTS UNDER 0.5 | 56.2% | 6 | WIN |
LAD@SD | SD +110 | 50.9% | 6 | WIN |