Orioles vs Yankees Prediction — AI Finds CAN'T MISS MLB Lines & Props (Jun 21)
Updated: 2025-06-19T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The Baltimore Orioles travel to face the New York Yankees on June 21, 2025, in a clash between third-in-the-division Orioles and a resurging Yankees squad trying to build on recent momentum. With Max Fried expected to counter Zach Eflin, pitching will be the key storyline in what looks to be a pitcher’s duel.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Jun 21, 2025
Start Time: 1:05 PM EST
Venue: Yankee Stadium
Yankees Record: (43-32)
Orioles Record: (33-42)
OPENING ODDS
BAL Moneyline: +142
NYY Moneyline: -169
BAL Spread: +1.5
NYY Spread: -1.5
Over/Under: 9.5
BAL
Betting Trends
- The Orioles are 32–43 against the spread (ATS) this season, but are 7–3 over their last ten games straight up, showing they’ve been competitive despite being underdogs.
NYY
Betting Trends
- The Yankees have struggled ATS overall with a roughly .440 record, including 16–17 as home favorites, but have started to rebound, covering in recent home matchups.
MATCHUP TRENDS
- This marks an intriguing contrast: Baltimore has played well overall recently, while New York is stronger as a home favorite, which could create a tight line scenario in this inter-divisional tilt.
BAL vs. NYY
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: C. Cowser over 0.5 Total Bases.
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Baltimore vs New York Yankees Prediction & Odds:
Free MLB Betting Insights for 6/21/25
Recent form favors both teams in their own ways—the Yankees have been gaining traction at home with improved bullpen outings and a disciplined lineup approach, while Baltimore has gone 7–3 in its last ten games and appears to be responding well under interim manager Tony Mansolino. Statistically, the Yankees have been stronger as home favorites, although their season ATS record is mediocre, while the Orioles continue to outperform straight up but struggle to cover spreads. This contrast suggests a tightly contested affair where the run line may be determined by one key inning or bullpen performance. Both teams’ bullpens have been question marks at times, though the Yankees have shown more late-game poise of late, and that could prove pivotal if Fried hands them a lead after six innings. If Baltimore keeps the game close into the eighth, their offensive discipline and improved defense give them a shot to steal a win. However, the Yankees’ top-end talent, home-field familiarity, and ability to strike quickly give them the edge in high-leverage moments. Expect a low-scoring affair where the outcome hinges on which starter blinks first and whose bullpen better absorbs pressure in the final frames.
it's not clocking to you that we're standing on business 🤨 pic.twitter.com/5J4bK2k7kr
— Baltimore Orioles (@Orioles) June 21, 2025
Baltimore Orioles MLB Preview
The Baltimore Orioles arrive at Yankee Stadium on June 21, 2025, with renewed confidence and a stronger sense of purpose than their overall record might suggest. Despite sitting at 33–42 entering this contest, the Orioles have surged recently with a 7–3 mark in their last ten games and an 11–6 record since interim manager Tony Mansolino took over in early June. This upswing reflects a team finding its identity after a tumultuous start to the season. Baltimore’s offense has been key to this turnaround, led by rising stars Gunnar Henderson and Adley Rutschman, who have delivered clutch hits and provided steady production in the heart of the lineup. Complemented by Cedric Mullins’ speed and contact approach, the Orioles have built a lineup that doesn’t rely on power alone but rather excels in manufacturing runs and extending innings through patience and baserunning aggression. Starting pitcher Zach Eflin gets the nod against the Yankees, carrying a 4.81 ERA that masks his potential when he’s locked in. Eflin has struggled with consistency this season, but his track record includes impressive outings against AL East opponents and a prior scoreless appearance versus New York, which should provide some confidence heading into this high-stakes divisional matchup.
Baltimore’s challenge will be twofold: supporting Eflin early with run support and navigating a Yankees bullpen that has recently rediscovered its sharpness. Defensively, the Orioles have improved, limiting costly mistakes that plagued them earlier in the season, and they’ll need to be sharp to contain the likes of Aaron Judge and Cody Bellinger in high-leverage moments. The Orioles’ bullpen has been hit-or-miss throughout the season, but with closer Craig Kimbrel and setup men showing flashes of dominance, they possess the pieces to hold leads if the starters can hand them over with an advantage. ATS-wise, Baltimore has underperformed this year, holding a sub-.450 record, yet their recent straight-up wins suggest they are closing the gap between potential and execution. The key for Baltimore will be maintaining discipline at the plate and executing fundamentally sound baseball—something they’ve excelled at in recent road games despite their 14–22 overall away record. Against an ace like Max Fried, the Orioles must make every base runner count and stay mentally tough through the middle innings, when the Yankees often shift momentum. If Eflin can navigate through Judge, Bellinger, and Stanton without early damage, and if the offense can scratch out a few timely runs, Baltimore could be in position to pull off an upset or at least stay well within the run line. The Orioles are underdogs on paper but have the talent, confidence, and recent performance to make this a highly competitive game against a division rival fighting to climb back into postseason relevance.

Credit: USA TODAY/IMAGN
New York Yankees Yankees MLB Preview
The New York Yankees host the Baltimore Orioles on June 21, 2025, with a growing sense of urgency and determination to reassert themselves as a force in the AL East. Coming into this matchup with a record hovering above .500 and a recent uptick in form at Yankee Stadium, the Yankees aim to build momentum on the back of elite starting pitching and a gradually stabilizing bullpen. The centerpiece of their strategy will be ace Max Fried, who has emerged as the clear leader of the rotation with a sparkling 1.89 ERA and pinpoint command that consistently shuts down top-tier offenses. Fried’s ability to work deep into games, limit walks, and suppress power makes him an ideal matchup against a Baltimore team that relies on contact and movement rather than slugging. Offensively, the Yankees are beginning to rediscover their identity with Aaron Judge leading the charge, supported by the left-handed power of Cody Bellinger and the versatile bats of Giancarlo Stanton and Jazz Chisholm Jr. While the offense has been streaky, it has shown signs of improved patience and production in key situations, particularly during recent home games where the team has covered the spread more reliably. Defensively, the Yankees are sound across the board, anchored by a sure-handed infield and an athletic outfield that can erase would-be extra-base hits.
Their bullpen, which had been a source of concern earlier in the season, has started to deliver more consistent results thanks to refined roles and fewer late-inning implosions, giving manager Aaron Boone confidence in matchups beyond the sixth inning. Against a surging Orioles club, the Yankees’ approach will be to strike early behind Fried’s dominance and force Baltimore to play catch-up, a scenario in which New York tends to thrive. Their ability to manufacture runs in the early innings and protect leads with strategic bullpen usage has defined their recent success, particularly at home where the comfort of their surroundings seems to enhance execution. The team has also responded well to high-pressure divisional games, which adds another layer of motivation heading into this one. While their overall against-the-spread record has been underwhelming, especially in broader season context, the Yankees have shown they can cover and win convincingly when their starting pitching is sharp and the bats are timely. If Fried can hold Baltimore scoreless through the early frames and Judge or Bellinger deliver a big hit to break the game open, the Yankees will be in prime position to not only win but cover the run line. With a well-rounded roster beginning to click and the advantage of home field, New York enters this contest poised to contain a hot Orioles squad and continue their pursuit of division leaders with a statement performance.
That's a Captain Crush. #ALLRISE 🫡 | Vote Yankees 🌟 https://t.co/eDVN5twbyd pic.twitter.com/OGy8wLNSiw
— New York Yankees (@Yankees) June 21, 2025
Baltimore vs. New York Yankees Prop Picks (AI)
Baltimore vs. New York Yankees Prediction (AI)

Remi, our AI sports genius, has been pouring over exorbitant amounts of data from every simulation between the Orioles and Yankees and using recursive machine learning and industry leading AI to boil down the data to a single cover probability.
The Algorithm has been most fixated on the trending factor human bettors tend to put on coaching factors between a Orioles team going up against a possibly tired Yankees team. We’ve found the true game analytics might reflect a strong lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.
Below is our current AI Baltimore vs New York Yankees picks, computer picks Orioles vs Yankees, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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MLB | 10/20 | SEA@TOR | UNLOCK THIS PICK | 2 |
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MLB | 10/20 | SEA@TOR | UNLOCK THIS PICK | 0 |
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.
Orioles Betting Trends
The Orioles are 32–43 against the spread (ATS) this season, but are 7–3 over their last ten games straight up, showing they’ve been competitive despite being underdogs.
Yankees Betting Trends
The Yankees have struggled ATS overall with a roughly .440 record, including 16–17 as home favorites, but have started to rebound, covering in recent home matchups.
Orioles vs. Yankees Matchup Trends
This marks an intriguing contrast: Baltimore has played well overall recently, while New York is stronger as a home favorite, which could create a tight line scenario in this inter-divisional tilt.
Baltimore vs. New York Yankees Game Info
What time does Baltimore vs New York Yankees start on June 21, 2025?
Baltimore vs New York Yankees starts on June 21, 2025 at 1:05 PM EST.
Where is Baltimore vs New York Yankees being played?
Venue: Yankee Stadium.
What are the opening odds for Baltimore vs New York Yankees?
Spread: New York Yankees -1.5
Moneyline: Baltimore +142, New York Yankees -169
Over/Under: 9.5
What are the records for Baltimore vs New York Yankees?
Baltimore: (33-42) | New York Yankees: (43-32)
What is the AI best bet for Baltimore vs New York Yankees?
Remi's searched hard and found the best prop for this matchup: C. Cowser over 0.5 Total Bases.. Prices move—always shop for the best number.
What are Baltimore vs New York Yankees trending bets?
This marks an intriguing contrast: Baltimore has played well overall recently, while New York is stronger as a home favorite, which could create a tight line scenario in this inter-divisional tilt.
What are Baltimore trending bets?
BAL trend: The Orioles are 32–43 against the spread (ATS) this season, but are 7–3 over their last ten games straight up, showing they’ve been competitive despite being underdogs.
What are New York Yankees trending bets?
NYY trend: The Yankees have struggled ATS overall with a roughly .440 record, including 16–17 as home favorites, but have started to rebound, covering in recent home matchups.
Where can I find AI Picks for Baltimore vs New York Yankees?
See our latest MLB picks and odds pages for 2025 to compare prices before you bet.
Baltimore vs. New York Yankees Odds
Remi is pouring through loads of data on each line. In fact, anytime the Baltimore vs New York Yankees trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme altitude seemingly never follow normal, predictable patterns.
Baltimore vs New York Yankees Opening Odds
BAL Moneyline:
+142 NYY Moneyline: -169
BAL Spread: +1.5
NYY Spread: -1.5
Over/Under: 9.5
Baltimore vs New York Yankees Live Odds
Games | PTS | ML | SPR | O/U | |
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Oct 24, 2025 8:00PM EDT
Los Angeles Dodgers
Toronto Blue Jays
10/24/25 8PM
Dodgers
Blue Jays
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–
–
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-148
+126
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-1.5 (+114)
+1.5 (-137)
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O 7.5 (+100)
U 7.5 (-122)
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MLB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Baltimore Orioles vs. New York Yankees Yankees on June 21, 2025 at Yankee Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
TOR@SEA | OVER 7 | 54.9% | 3 | WIN |
LAD@MIL | UNDER 7.5 | 56.6% | 6 | WIN |
TOR@NYY | OVER 8 | 54.9% | 4 | WIN |
TOR@NYY | CARLOS RODON OVER 1.5 TOTAL WALKS ALLOWED | 53.3% | 3 | WIN |
NYY@TOR | OVER 7.5 | 54.8% | 2 | WIN |
LAD@PHI | OVER 7 | 53.8% | 3 | WIN |
SD@CHC | CHC -109 | 53.8% | 3 | WIN |
SD@CHC | OVER 7.5 | 54.5% | 4 | LOSS |
SD@CHC | CHC -111 | 54.8% | 4 | LOSS |
CIN@LAD | SHOHEI OHTANI OVER 1.5 BASES | 53.5% | 3 | WIN |
BOS@NYY | OVER 7 | 53.8% | 3 | LOSS |
CIN@LAD | ELLY DE LA CRUZ OVER 0.5 BASES | 54.4% | 4 | LOSS |
ARI@SD | SD -131 | 57.3% | 4 | WIN |
DET@BOS | BOS -115 | 56.4% | 5 | WIN |
NYM@CHC | NYM -110 | 54.1% | 3 | WIN |
HOU@ATH | ATH +118 | 50.8% | 4 | WIN |
NYM@CHC | OVER 7 | 54.5% | 3 | WIN |
STL@SF | OVER 7.5 | 55.9% | 5 | LOSS |
KC@LAA | TYLER TOLBERT UNDER 1.5 BASES | 54.4% | 4 | WIN |
MIL@SD | UNDER 9 | 54.7% | 4 | WIN |
MIA@PHI | KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS | 53.3% | 3 | WIN |
WAS@NYM | OVER 8.5 | 56.1% | 6 | LOSS |
LAA@COL | COL +108 | 50.5% | 3 | WIN |
TOR@KC | UNDER 9 | 54.7% | 4 | LOSS |
SEA@KC | KC +1.5 | 62.3% | 5 | LOSS |
NYY@MIN | OVER 9 | 55.1% | 4 | WIN |
MIA@COL | OVER 10.5 | 55.0% | 4 | WIN |
MIA@COL | AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS | 54.3% | 4 | WIN |
SEA@KC | BOBBY WITT UNDER 0.5 SINGLES | 54.4% | 4 | LOSS |
PHI@LAD | LAD -113 | 54.7% | 4 | LOSS |
NYY@BOS | OVER 7.5 | 54.3% | 3 | WIN |
KC@PHI | PHI -130 | 58.3% | 4 | WIN |
LAD@SF | OVER 7.5 | 54.7% | 4 | LOSS |
NYM@PHI | PHI -122 | 55.6% | 4 | WIN |
KC@CLE | KC -104 | 52.0% | 3 | WIN |
CIN@SD | JAKE CRONEWORTH OVER 0.5 HITS | 53.1% | 3 | WIN |
WAS@MIA | MIA -123 | 55.2% | 4 | LOSS |
LAA@KC | UNDER 9.5 | 54.9% | 3 | WIN |
TEX@ARI | UNDER 9 | 54.2% | 4 | WIN |
SF@COL | UNDER 11.5 | 56.4% | 6 | LOSS |
SF@COL | RAFAEL DEVERS OVER 1.5 BASES | 56.1% | 6 | WIN |
MIA@WAS | WAS -110 | 54.4% | 4 | WIN |
NYM@DET | OVER 8.5 | 54.5% | 4 | WIN |
TEX@ARI | UNDER 9.5 | 56.4% | 6 | WIN |
TEX@ARI | ALEJANDRO OSUNA UNDER 1.5 BASES | 54.1% | 4 | LOSS |
ATL@CHC | CHC -116 | 55.1% | 3 | WIN |
PHI@MIL | OVER 8.5 | 55.0% | 3 | WIN |
ARI@LAD | SHOHEI OHTANI OVER 2.5 BASES | 54.2% | 4 | WIN |
SEA@CLE | CLE +1.5 | 57.2% | 3 | WIN |
CHC@SF | CHC -105 | 54.1% | 4 | LOSS |
NYY@CHW | RYAN MCMAHON OVER 0.5 BASES | 54.1% | 4 | WIN |