Red Sox vs. Giants
Prediction, Odds & Props
Jun 20 | MLB AI Picks

Updated: 2025-06-18T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Boston Red Sox open a three-game series at Oracle Park against the San Francisco Giants on June 20, 2025, with first pitch scheduled for 10:15 p.m. ET. San Francisco enters as a moderate favorite (around −125), with the total set near 9, pointing toward a potentially close, pitcher-friendly duel.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Jun 20, 2025

Start Time: 10:15 PM EST​

Venue: Oracle Park​

Giants Record: (42-33)

Red Sox Record: (39-37)

OPENING ODDS

BOS Moneyline: +110

SF Moneyline: -132

BOS Spread: +1.5

SF Spread: -1.5

Over/Under: 7.5

BOS
Betting Trends

  • The Red Sox are roughly 5–5 ATS in their last 10 games, maintaining a middling performance against the spread through June.

SF
Betting Trends

  • The Giants are 22–12 at home this season and a strong 4–2 in their last 30 home games, showing solid performance under familiar conditions.

MATCHUP TRENDS

  • San Francisco’s games have hit the under in 30 of their last 47 outings, while Boston’s recent games have seen mixed outcomes—suggesting the total of around 9 could tilt toward the under.

BOS vs. SF
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: C. Narvaez over 5 Fantasy Score.

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Boston vs San Francisco Prediction & Odds:
Free MLB Betting Insights for 6/20/25

Friday’s interleague opener between the Boston Red Sox and San Francisco Giants at Oracle Park offers a fascinating mix of narrative tension, tactical intrigue, and playoff implications for both clubs. The game not only marks a crucial juncture in the season for the Red Sox, who recently traded longtime star Rafael Devers to San Francisco, but it also pits two teams with contrasting styles and similar ambitions in what is expected to be a low-scoring, tightly contested matchup. San Francisco, boasting a 41–33 record and an excellent 22–12 mark at home, has quietly emerged as one of the more dependable teams in the National League thanks to elite pitching and disciplined execution. Their 3.26 team ERA ranks among the best in baseball, and they’ve built a home-field identity centered around strong starts and shutdown bullpen work in close games. Meanwhile, Boston enters the series at 39–37, looking to reset their identity post-Devers by leaning into their pitching depth, youth movement, and a lineup that emphasizes speed and situational hitting over power. The recent success of young contributors like Roman Anthony and the steady presence of Trevor Story and Triston Casas have allowed Boston to stay competitive despite offensive turnover. The pitching matchup isn’t officially confirmed but based on rotation trends, San Francisco may go with a home-tested arm like Keaton Winn or Jordan Hicks, both of whom have had success keeping the ball in the park and managing traffic on the bases.

Boston could counter with a mid-rotation arm, potentially someone like Cooper Criswell or another righty with a solid command profile, looking to give six innings of contact-managed performance before turning it over to their bullpen. Both teams have leaned heavily on the under in recent weeks—San Francisco’s games have stayed under the total in 30 of their last 47, while Boston has had mixed results but tends to go under on the road, particularly in large parks like Oracle. The total for this game is set near 9, which reflects the bookmakers’ respect for each team’s ability to limit scoring despite not fielding top-five offenses. San Francisco’s lineup is paced by breakout performers like Heliot Ramos and veterans like Matt Chapman, whose combined 23 home runs offer punch in the middle, but the Giants more often rely on manufacturing runs through plate discipline, deep counts, and timely hits. Boston’s offensive approach, meanwhile, is built around contact hitting and basepath aggression, as they attempt to string together innings with multiple contributors rather than leaning on any single superstar. The key battleground will be the middle innings—whichever team can strike first in the fifth or sixth while still having fresh bullpen arms to control the seventh through ninth will likely control the tempo and outcome. Expect both managers to manage aggressively with substitutions and matchups, especially if it’s a one-run game going into the final three innings. Given how closely these teams match up and how they each thrive in low-scoring environments, a 4–3 or 3–2 finish feels probable, with the Giants holding a slight edge due to home-field consistency and bullpen command in late innings.

Boston Red Sox MLB Preview

The Boston Red Sox enter Friday’s interleague opener against the San Francisco Giants at Oracle Park carrying a 39–37 record and a mix of urgency and uncertainty after the recent trade of longtime franchise cornerstone Rafael Devers. That deal sent shockwaves through the clubhouse and the league, and now Boston must begin reshaping its identity around emerging talent and situational execution rather than middle-of-the-order power. The Red Sox have shown flashes of resilience on the road this season, going 17–20 away from Fenway Park and splitting their last 10 games against the spread, a sign of a team still seeking consistency. Without Devers, Boston leans heavily on the growth of players like Roman Anthony, whose patient plate approach and gap power have sparked recent rallies, and Triston Casas, a steady presence who blends power and contact in the middle of the lineup. Trevor Story, when healthy, remains one of the team’s most important two-way players, offering gold-glove caliber defense and timely extra-base hits that often tilt close games. The team’s offensive approach now emphasizes line-drive contact, plate discipline, and aggressive baserunning—attributes that should play well in the spacious confines of Oracle Park, where home runs are rare and manufacturing runs is essential.

On the mound, Boston’s rotation has quietly become a strength, and Friday’s start will likely go to a mid-tier arm such as Cooper Criswell or Tanner Houck depending on rest schedules, both of whom have posted reliable WHIP numbers and shown the ability to work through tough lineups. Their job will be to keep traffic off the bases and minimize the long innings that have plagued Boston in higher-scoring parks. The bullpen has stabilized as well, with quality performances from arms like Chris Martin and Kenley Jansen, allowing manager Alex Cora to match up effectively in late innings. If Boston can keep this game tight through five, they’ll be in position to use their leverage relievers to shut the door. From a betting perspective, Boston games have been a mix of overs and unders recently, but their road matchups at pitcher-friendly parks have generally leaned under, which supports Friday’s total hovering around 9 runs. The challenge in this game is not just facing a strong Giants pitching staff, but doing so in a park where offense is difficult to come by, and where Boston’s newer offensive pieces will have to prove they can execute situationally without the benefit of Devers’ bat. If the Red Sox can jump on San Francisco early and avoid relying solely on late-inning heroics, they have a legitimate shot to steal a close road win. It may not be flashy, but a 4–3 or 3–2 Boston victory would be perfectly on brand for a team redefining itself through balance, hustle, and bullpen grit. With every game now critical for staying in AL Wild Card contention, Boston’s ability to adapt quickly to its post-Devers reality will be on full display under the West Coast lights.

The Boston Red Sox open a three-game series at Oracle Park against the San Francisco Giants on June 20, 2025, with first pitch scheduled for 10:15 p.m. ET. San Francisco enters as a moderate favorite (around −125), with the total set near 9, pointing toward a potentially close, pitcher-friendly duel. Boston vs San Francisco AI Prediction: Free MLB Betting Insights for Jun 20. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

San Francisco Giants MLB Preview

The San Francisco Giants come into Friday night’s matchup against the visiting Boston Red Sox with a 41–33 record and an impressive 22–12 mark at Oracle Park, where their methodical, fundamentally sound style of play thrives. The team has become one of the most quietly effective clubs in the National League, winning games through pitching depth, strong defense, and a strategic offensive approach that capitalizes on mistakes and high-leverage opportunities. Since acquiring Rafael Devers in a blockbuster trade with Boston, the Giants not only added one of the game’s premier left-handed power bats to their lineup but also a familiar face for this particular matchup, as Devers will now face the team he spent his entire career with up to this point. Devers joins a lineup that already features key contributors like Heliot Ramos, who leads the team in home runs with 12, and Matt Chapman, whose combination of power, defense, and veteran presence gives San Francisco a stable core capable of playing both small ball and long ball. The Giants’ offensive identity is built around patience and execution, which aligns perfectly with the tendencies of Oracle Park, where home runs are rare and productive outs often win games. Their lineup doesn’t overwhelm opponents with slugging, but they grind at-bats, drive up pitch counts, and capitalize on runners in scoring position—especially at home, where their run production has been more consistent than on the road.

On the mound, San Francisco could turn to a reliable starter like Jordan Hicks or Logan Webb depending on rest and rotation order, both of whom have performed well at home and give the Giants a legitimate shot to control the game from the outset. Hicks in particular has been a revelation, converting from a bullpen role to a starting job with great success by limiting hard contact and stretching into the sixth inning with minimal damage. San Francisco’s bullpen is a major asset, led by a mix of strikeout arms and ground-ball specialists that have helped the club finish games cleanly, contributing to their frequent under results—30 of their last 47 games have stayed under the total. This pitching-first, defense-second formula has been remarkably effective at Oracle, where the Giants have covered the spread consistently and built a reputation for late-inning control. If the Giants can get five to six solid innings from their starter and hand a lead to their bullpen, they’ll be well positioned to close out a tight game. Facing a Boston team without Rafael Devers and with a lineup that’s still adjusting to a new identity, the Giants should be able to lean on their pitching, defense, and timely hits to manage the game’s tempo and dictate terms. Expect a focused, measured performance from San Francisco that doesn’t aim for explosive innings but rather a consistent run or two each third of the game, resulting in a likely 4–3 or 5–2 victory that reflects how well they’ve executed this script all season long. With home dominance and a renewed lineup, the Giants look ready to take full advantage of a Red Sox team still searching for balance.

Boston vs. San Francisco Prop Picks (AI)

AI algorithm Remi is pouring through mountains of stats on each line. In fact, anytime the Red Sox and Giants play there’s always several intriguing observations to key in on. Not to mention games played at Oracle Park in Jun can often follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: C. Narvaez over 5 Fantasy Score.

Boston vs. San Francisco Prediction (AI)

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Remi, our AI sports genius, has been pouring over exorbitant amounts of data from every simulation between the Red Sox and Giants and using recursive machine learning and industry leading AI to analyze the data to a single cover probability.

The Algorithm has been most focused on the growing weight emotional bettors often put on player performance factors between a Red Sox team going up against a possibly healthy Giants team. It appears the true game analytics appear to reflect a moderate lean against one Vegas line specifically.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI Boston vs San Francisco picks, computer picks Red Sox vs Giants, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
MLB 9/26 DET@BOS UNLOCK THIS PICK 5 EXECUTIVE Locked EXECUTIVE
MLB 9/26 BAL@NYY UNLOCK THIS PICK 4 INTEL Locked INTEL
MLB 9/26 ARI@SD UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
MLB 9/26 NYM@MIA UNLOCK THIS PICK 1 INTEL Locked INTEL
MLB 9/26 NYM@MIA GET FREE PICK NOW 1
MLB 9/26 COL@SF UNLOCK THIS PICK 0 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

Red Sox Betting Trends

The Red Sox are roughly 5–5 ATS in their last 10 games, maintaining a middling performance against the spread through June.

Giants Betting Trends

The Giants are 22–12 at home this season and a strong 4–2 in their last 30 home games, showing solid performance under familiar conditions.

Red Sox vs. Giants Matchup Trends

San Francisco’s games have hit the under in 30 of their last 47 outings, while Boston’s recent games have seen mixed outcomes—suggesting the total of around 9 could tilt toward the under.

Boston vs. San Francisco Game Info

Boston vs San Francisco starts on June 20, 2025 at 10:15 PM EST.

Spread: San Francisco -1.5
Moneyline: Boston +110, San Francisco -132
Over/Under: 7.5

Boston: (39-37)  |  San Francisco: (42-33)

Remi's searched hard and found the best prop for this matchup: C. Narvaez over 5 Fantasy Score.. Prices move—always shop for the best number.

San Francisco’s games have hit the under in 30 of their last 47 outings, while Boston’s recent games have seen mixed outcomes—suggesting the total of around 9 could tilt toward the under.

BOS trend: The Red Sox are roughly 5–5 ATS in their last 10 games, maintaining a middling performance against the spread through June.

SF trend: The Giants are 22–12 at home this season and a strong 4–2 in their last 30 home games, showing solid performance under familiar conditions.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

Boston vs. San Francisco Odds

AI algorithm Remi is pouring through loads of stats on each line. In fact, anytime the Boston vs San Francisco trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme hostile environments almost always follow normal, predictable betting trends.

Boston vs San Francisco Opening Odds

BOS Moneyline: +110
SF Moneyline: -132
BOS Spread: +1.5
SF Spread: -1.5
Over/Under: 7.5

Boston vs San Francisco Live Odds

Games PTS ML SPR O/U
Sep 27, 2025 1:06PM EDT
Baltimore Orioles
New York Yankees
9/27/25 1:06PM
Orioles
Yankees
+190
-235
+1.5 (-105)
-1.5 (-115)
O 8.5 (-120)
U 8.5 (+100)
Sep 27, 2025 2:21PM EDT
St Louis Cardinals
Chicago Cubs
9/27/25 2:21PM
Cardinals
Cubs
 
-175
 
-1.5 (+115)
O 9.5 (-105)
U 9.5 (-115)
Sep 27, 2025 3:09PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/27/25 3:09PM
Rays
Blue Jays
+135
-165
+1.5 (-165)
-1.5 (+135)
O 8.5 (+100)
U 8.5 (-120)
Sep 27, 2025 4:06PM EDT
Chicago White Sox
Washington Nationals
9/27/25 4:06PM
White Sox
Nationals
+100
-120
-1.5 (+155)
+1.5 (-190)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 4:06PM EDT
Colorado Rockies
San Francisco Giants
9/27/25 4:06PM
Rockies
Giants
+185
-225
+1.5 (-110)
-1.5 (-110)
O 8 (-105)
U 8 (-115)
Sep 27, 2025 4:11PM EDT
New York Mets
Miami Marlins
9/27/25 4:11PM
Mets
Marlins
-130
+110
-1.5 (+125)
+1.5 (-150)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
+170
-205
+1.5 (-120)
-1.5 (+100)
O 8.5 (-115)
U 8.5 (-105)
Sep 27, 2025 6:12PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 6:12PM
Rangers
Guardians
+135
-165
+1.5 (-170)
-1.5 (+140)
O 7 (-120)
U 7 (+100)
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
+125
-150
+1.5 (-175)
-1.5 (+145)
O 8 (-105)
U 8 (-115)
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
+140
-170
+1.5 (-165)
-1.5 (+135)
O 8 (-115)
U 8 (-105)
Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
+115
-140
+1.5 (-190)
-1.5 (+155)
O 7.5 (-115)
U 7.5 (-105)
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
+105
-125
+1.5 (-205)
-1.5 (+170)
O 7.5 (-110)
U 7.5 (-110)
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
-105
-115
-1.5 (+150)
+1.5 (-180)
O 10 (-110)
U 10 (-110)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Boston Red Sox vs. San Francisco Giants on June 20, 2025 at Oracle Park.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS
CIN@ARI KEBRYAN HAYES STRIKEOUTS UNDER 0.5 56.2% 6 WIN
LAD@SD SD +110 50.9% 6 WIN