Padres vs Dodgers Prediction — AI Finds CAN'T MISS MLB Lines & Props (Jun 16)

Updated: 2025-06-14T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Los Angeles Dodgers (43–29) host the San Diego Padres (39–31) on Monday, June 16, 2025, at Dodger Stadium, with first pitch scheduled for 10:10 PM ET. This game marks Shohei Ohtani’s highly anticipated return to the mound, his first pitching appearance since August 2023 following Tommy John surgery, adding significant intrigue to this pivotal NL West matchup.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Jun 16, 2025

Start Time: 10:10 PM EST​

Venue: Dodger Stadium​

Dodgers Record: (43-29)

Padres Record: (39-31)

OPENING ODDS

SD Moneyline: +131

LAD Moneyline: -156

SD Spread: +1.5

LAD Spread: -1.5

Over/Under: 9

SD
Betting Trends

  • The Padres have covered the run line in 7 of their last 10 games, demonstrating strong recent performance against the spread.

LAD
Betting Trends

  • The Dodgers have struggled against the spread recently, going 1–7 ATS in their last 8 games, despite maintaining a solid 5–2 straight-up record in their last 7 matchups against the Padres.

MATCHUP TRENDS

  • The total has gone OVER in 9 of the Dodgers’ last 13 games, and in 4 of their last 6 games against the Padres, indicating a trend toward high-scoring affairs when these teams meet.

SD vs. LAD
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: M. Conforto over 0.5 Hits+Runs+RBI.

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San Diego vs Los Angeles Dodgers Prediction & Odds:
Free MLB Betting Insights for 6/16/25

Monday night’s NL West clash between the Los Angeles Dodgers and the San Diego Padres at Dodger Stadium is set to be one of the most anticipated games of the season, not just because of the division implications, but also due to the long-awaited return of Shohei Ohtani to the mound. Ohtani, sidelined since August 2023 after undergoing Tommy John surgery, is expected to make his first pitching appearance in 21 months in a limited “piggyback” role, likely throwing one inning before handing the game over to the bullpen. His dual-threat presence has already made him one of the most valuable players in the league, with a .297 batting average, 25 home runs, and a 1.035 OPS heading into this matchup. The Dodgers, 43–29 and currently sitting atop the division, are doing so despite having 14 pitchers on the injured list, including major arms like Tyler Glasnow, Blake Snell, and Roki Sasaki, which makes Ohtani’s return not only symbolic but critical for their rotation depth moving forward. The offense has carried the Dodgers through this difficult stretch, leading the majors with 5.83 runs per game and consistently applying pressure with a lineup that includes Freddie Freeman, Mookie Betts, Teoscar Hernández, and the MVP-level production from Ohtani.

On the other side, the Padres come into the game at 39–31, just four games back in the division, and playing their best baseball of the season, having covered the run line in seven of their last ten games and competing well against playoff-caliber opponents. San Diego’s offense has been clicking, averaging 5.26 runs per game—fifth-best in MLB—and driven by Fernando Tatis Jr., Manny Machado, and Xander Bogaerts, who have found more consistency in recent weeks. Their pitching staff, slightly outperforming the Dodgers with a 4.41 team ERA compared to L.A.’s 4.44, has been steady if not spectacular, with reliable middle relief and a closing corps that has held firm in tight games. The Padres know the key to winning at Dodger Stadium is to withstand early offensive surges and force the game into middle innings, where they can exploit matchups and potentially take advantage of L.A.’s injury-thinned bullpen. Given recent trends, including the total going OVER in four of the last six meetings and in nine of the Dodgers’ last thirteen games overall, fans should expect a high-scoring affair—especially if Ohtani only pitches briefly and both teams lean heavily on their bullpens. For the Dodgers, the emotional lift and national spotlight of Ohtani’s return could be the spark that sets the tone for the series, while for the Padres, this game offers a golden opportunity to close the gap in the standings and make a statement that they’re not just chasing—they’re ready to challenge. With playoff energy, star power across both dugouts, and a divisional rivalry that always brings intensity, Monday’s game is a must-watch and a potential turning point in the race for NL West supremacy.

San Diego Padres MLB Preview

The San Diego Padres enter Monday night’s matchup at Dodger Stadium with a 39–31 record, sitting four games behind the division-leading Los Angeles Dodgers and eyeing a key opportunity to chip away at the NL West gap. After a slow start to the season, the Padres have hit their stride in June, covering the run line in seven of their last ten games and showcasing the type of balanced roster that was expected when the year began. Their offense, averaging 5.26 runs per game—fifth best in MLB—has been carried by the resurgence of their core stars, with Fernando Tatis Jr. and Manny Machado leading the way. Tatis, blending speed and power, has been one of the hottest hitters in baseball recently, while Machado has provided timely RBIs and stabilized the middle of the order. Xander Bogaerts has also found rhythm after a cold stretch, giving the Padres a dangerous trio that can handle elite pitching and change the game with one swing. Alongside them, Jake Cronenworth and Ha-Seong Kim have added versatility and on-base presence, allowing San Diego to apply pressure from top to bottom in the lineup Pitching-wise, the Padres bring a slightly better team ERA (4.41) than their injury-depleted rivals, the Dodgers (4.44), and their starting rotation has kept them competitive even in tight games. While the Padres haven’t relied on dominant frontline arms this season, they’ve leaned on consistency, with starters often delivering quality innings and keeping the bullpen fresh for late-game situations.

The bullpen itself, anchored by closer Robert Suárez and setup men like Yuki Matsui and Wandy Peralta, has been one of the team’s strongest assets, particularly in recent weeks as the Padres have won multiple close games with shutdown ninth innings. San Diego’s success in this game will hinge on pitching efficiency and defensive execution—two areas where they’ve been solid but not elite. Limiting walks and turning routine plays into outs will be crucial, especially in a high-offense environment like Dodger Stadium, where momentum can swing with one missed opportunity. From a strategic standpoint, the Padres will look to be patient at the plate against Shohei Ohtani, who is expected to pitch for the first time in nearly two years and will likely go just one inning before giving way to the bullpen. San Diego’s goal will be to force deep counts, wear down L.A.’s relievers early, and capitalize in the middle innings when the Dodgers’ patchwork bullpen is most vulnerable. Given their recent ATS success, San Diego enters this matchup with confidence, and a win on Monday could serve as a crucial swing game in the division race. With playoff-caliber offense, solid bullpen depth, and momentum on their side, the Padres are in prime position to test the Dodgers’ durability and potentially send a message that the NL West will be contested all the way through September.

The Los Angeles Dodgers (43–29) host the San Diego Padres (39–31) on Monday, June 16, 2025, at Dodger Stadium, with first pitch scheduled for 10:10 PM ET. This game marks Shohei Ohtani’s highly anticipated return to the mound, his first pitching appearance since August 2023 following Tommy John surgery, adding significant intrigue to this pivotal NL West matchup. San Diego vs Los Angeles Dodgers AI Prediction: Free MLB Betting Insights for Jun 16. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Los Angeles Dodgers Dodgers MLB Preview

The Los Angeles Dodgers return to Chavez Ravine on Monday night with a 43–29 record, leading the NL West by two games and welcoming division rival San Diego for a crucial showdown that also marks Shohei Ohtani’s highly anticipated return to the mound. Despite an unprecedented stretch of injuries to their pitching staff—14 pitchers currently on the IL including Roki Sasaki, Blake Snell, and Tyler Glasnow—the Dodgers have maintained their division lead thanks to one of the most explosive offenses in baseball and a relentless next-man-up mentality throughout the roster. Monday’s game will see Ohtani pitch for the first time since August 2023 in a brief “piggyback” appearance, likely working just one inning as he continues his two-way comeback following Tommy John surgery. While his pitching role remains limited, his impact at the plate has been immense; Ohtani leads the team with a .297 average, 25 home runs, and a 1.035 OPS, making him a frontrunner once again for MVP honors. He’s supported by a stacked lineup that includes Mookie Betts, Freddie Freeman, and Teoscar Hernández, each of whom brings power, discipline, and experience in big moments. The Dodgers have averaged a league-leading 5.83 runs per game this season, consistently applying pressure early and generating big innings even when trailing. They’ve relied heavily on their offense to carry them through tight spots during this injury-laden stretch, and the results have been impressive—particularly in games where the bullpen has been able to protect narrow leads.

That bullpen, while fatigued from constant usage, has been stabilized in part by the emergence of new arms and clutch performances from veterans like Ryan Brasier and Alex Vesia. Manager Dave Roberts has had to be creative with his rotation and bullpen structure due to the absence of regular starters, but the team has responded well, going 5–2 straight up in their last seven games against San Diego. Still, they’ve struggled against the spread, going just 1–7 ATS in their last eight games, often winning but failing to cover due to narrow margins and late-game runs allowed. Defensively, the Dodgers remain efficient, with Betts excelling in his transition to second base and Will Smith continuing to manage the pitching staff with elite game-calling behind the plate. Against the Padres, the Dodgers know they’ll need to keep their foot on the gas offensively, especially with San Diego’s bullpen ranking among the best in the National League. The key for Los Angeles will be jumping out early during Ohtani’s scheduled inning and then maintaining that momentum through the middle frames with aggressive at-bats and smart baserunning. This game also offers a major emotional lift—not just for the team but for the fanbase—as Ohtani’s return to pitching marks a symbolic chapter in the franchise’s season-long battle with adversity. A win on Monday would not only solidify the Dodgers’ hold on the division but would also serve as a reminder that even with a bruised rotation, their roster is deep, talented, and still built to contend at the highest level. The atmosphere will be electric, the spotlight intense, and if the Dodgers can pair Ohtani’s return with a victory over their closest division challenger, it could be the type of moment that defines the trajectory of their summer.

San Diego vs. Los Angeles Dodgers Prop Picks (AI)

Remi is pouring through tons of stats on each player. In fact, anytime the Padres and Dodgers play there’s always several intriguing trends to key in on. Not to mention games played at Dodger Stadium in Jun seemingly never follow normal, predictable patterns.
Remi's searched hard and found the best prop for this matchup: M. Conforto over 0.5 Hits+Runs+RBI.

San Diego vs. Los Angeles Dodgers Prediction (AI)

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Remi, our AI sports wizard, has been pouring over millions of data from every angle between the Padres and Dodgers and using recursive machine learning and cutting-edge AI to boil down the data to a single cover probability.

The Algorithm has been most fixated on the linear correlation of emphasis human bettors tend to put on Los Angeles Dodgers’s strength factors between a Padres team going up against a possibly healthy Dodgers team. We’ve found the true game analytics might reflect a slight lean against one Vegas line specifically.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI San Diego vs Los Angeles Dodgers picks, computer picks Padres vs Dodgers, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
MLB 10/20 SEA@TOR UNLOCK THIS PICK 2 INTEL Locked INTEL
MLB 10/20 SEA@TOR UNLOCK THIS PICK 0 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

Padres Betting Trends

The Padres have covered the run line in 7 of their last 10 games, demonstrating strong recent performance against the spread.

Dodgers Betting Trends

The Dodgers have struggled against the spread recently, going 1–7 ATS in their last 8 games, despite maintaining a solid 5–2 straight-up record in their last 7 matchups against the Padres.

Padres vs. Dodgers Matchup Trends

The total has gone OVER in 9 of the Dodgers’ last 13 games, and in 4 of their last 6 games against the Padres, indicating a trend toward high-scoring affairs when these teams meet.

San Diego vs. Los Angeles Dodgers Game Info

San Diego vs Los Angeles Dodgers starts on June 16, 2025 at 10:10 PM EST.

Spread: Los Angeles Dodgers -1.5
Moneyline: San Diego +131, Los Angeles Dodgers -156
Over/Under: 9

San Diego: (39-31)  |  Los Angeles Dodgers: (43-29)

Remi's searched hard and found the best prop for this matchup: M. Conforto over 0.5 Hits+Runs+RBI.. Prices move—always shop for the best number.

The total has gone OVER in 9 of the Dodgers’ last 13 games, and in 4 of their last 6 games against the Padres, indicating a trend toward high-scoring affairs when these teams meet.

SD trend: The Padres have covered the run line in 7 of their last 10 games, demonstrating strong recent performance against the spread.

LAD trend: The Dodgers have struggled against the spread recently, going 1–7 ATS in their last 8 games, despite maintaining a solid 5–2 straight-up record in their last 7 matchups against the Padres.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

San Diego vs. Los Angeles Dodgers Odds

AI algorithm Remi is pouring through tons of stats on each line. In fact, anytime the San Diego vs Los Angeles Dodgers trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme altitude almost always follow normal, predictable patterns.

San Diego vs Los Angeles Dodgers Opening Odds

SD Moneyline: +131
LAD Moneyline: -156
SD Spread: +1.5
LAD Spread: -1.5
Over/Under: 9

San Diego vs Los Angeles Dodgers Live Odds

Games PTS ML SPR O/U
Oct 24, 2025 9:08PM EDT
Los Angeles Dodgers
Toronto Blue Jays
10/24/25 9:08PM
Dodgers
Blue Jays
-149
+122
-1.5 (+119)
+1.5 (-145)
O 7 (-125)
U 7 (+103)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers San Diego Padres vs. Los Angeles Dodgers Dodgers on June 16, 2025 at Dodger Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
TOR@SEA OVER 7 54.9% 3 WIN
LAD@MIL UNDER 7.5 56.6% 6 WIN
TOR@NYY OVER 8 54.9% 4 WIN
TOR@NYY CARLOS RODON OVER 1.5 TOTAL WALKS ALLOWED 53.3% 3 WIN
NYY@TOR OVER 7.5 54.8% 2 WIN
LAD@PHI OVER 7 53.8% 3 WIN
SD@CHC CHC -109 53.8% 3 WIN
SD@CHC OVER 7.5 54.5% 4 LOSS
SD@CHC CHC -111 54.8% 4 LOSS
CIN@LAD SHOHEI OHTANI OVER 1.5 BASES 53.5% 3 WIN
BOS@NYY OVER 7 53.8% 3 LOSS
CIN@LAD ELLY DE LA CRUZ OVER 0.5 BASES 54.4% 4 LOSS
ARI@SD SD -131 57.3% 4 WIN
DET@BOS BOS -115 56.4% 5 WIN
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN