Reds vs Guardians Prediction — AI Finds CAN'T MISS MLB Lines & Props (Jun 11)
Updated: 2025-06-09T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The Cincinnati Reds and Cleveland Guardians are set to conclude their three-game series at Progressive Field on June 11, 2025, with first pitch scheduled for 1:10 PM EDT. Both teams are looking to gain momentum as they approach the midpoint of the season.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Jun 11, 2025
Start Time: 1:10 PM EST
Venue: Progressive Field
Guardians Record: (34-32)
Reds Record: (35-33)
OPENING ODDS
CIN Moneyline: -104
CLE Moneyline: -116
CIN Spread: -1.5
CLE Spread: +1.5
Over/Under: 8.5
CIN
Betting Trends
- The Cincinnati Reds have a 30–27 record against the spread (ATS) this season, indicating a solid performance in covering the run line.
CLE
Betting Trends
- The Cleveland Guardians have a 28–18 record ATS, showcasing their effectiveness in covering the spread, particularly at home.
MATCHUP TRENDS
- In their last five head-to-head matchups, the Reds have won four games against the Guardians, suggesting a recent edge in this interleague rivalry.
CIN vs. CLE
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: T. Friedl over 0.5 Total Bases.
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Cincinnati vs Cleveland Prediction & Odds:
Free MLB Betting Insights for 6/11/25
Around him, young contributors like Steven Kwan and Andrés Giménez have stepped up with clutch at-bats and smart defensive play, helping Cleveland execute their signature style of small-ball success. Cleveland’s pitching rotation, despite injuries to key arms earlier in the season, has held up well, and their bullpen remains among the best in the league, frequently locking down narrow leads with Emmanuel Clase anchoring the ninth inning. The Guardians play with a fundamentally sound style that emphasizes putting the ball in play, taking the extra base, and avoiding self-inflicted mistakes—traits that serve them well in tight, low-scoring contests. The biggest variable heading into this finale is how both offenses handle pressure with runners in scoring position, as both clubs have had their share of missed opportunities this season. Cincinnati’s tendency to strike out can become an issue against Cleveland’s contact-oriented pitching staff, while the Guardians will need to overcome a Reds bullpen that’s been stingy in late innings. In what projects to be a close game, managerial decisions, defensive execution, and bullpen usage will be pivotal. With both teams tightly bunched in their respective playoff chases and looking to build momentum before the All-Star break, this finale is poised to be fiercely contested, potentially setting the tone for how each club approaches the crucial weeks ahead. A win for either side would not just pad the standings, but also serve as a confidence boost in their pursuit of postseason relevance.
The best ever Abbott Day pic.twitter.com/gZoPTYWj5s
— Cincinnati Reds (@Reds) June 11, 2025
Cincinnati Reds MLB Preview
The Cincinnati Reds approach the final game of their interleague series against the Cleveland Guardians with a 34–33 record and a clear sense of urgency as they try to gain ground in the tightly packed NL Central. This team has hovered around the .500 mark for most of the season, occasionally flashing the potential to put together a sustained winning streak, and this matchup provides another opportunity to assert themselves against a strong opponent. The Reds’ offense is centered around dynamic young talents like Elly De La Cruz, whose electrifying speed, power, and athleticism make him one of the most watchable players in baseball. De La Cruz, along with Spencer Steer and Jonathan India, has helped create a top half of the lineup that can do damage in a variety of ways—whether it’s launching balls into the seats or using speed to put pressure on opposing defenses. The Reds average just under five runs per game, and when they’re clicking offensively, they’re a difficult team to pitch to because of their ability to work counts and force mistakes. Cincinnati’s pitching staff has been serviceable, though not dominant, with inconsistency from the rotation occasionally putting stress on the bullpen. However, the relief corps has been a pleasant surprise this year, with closer Alexis Díaz continuing to thrive in high-leverage situations and middle relievers stepping up when needed.
The key to their success has been their ability to shorten games—if the starters can keep it close through five innings, the bullpen often finishes the job. Cincinnati’s defense has also improved significantly, with De La Cruz and Matt McLain providing range and reliability in the middle infield, and the outfield trio showcasing solid arms and tracking ability. Their 30–27 record against the spread shows they’ve often been more competitive than their overall record might suggest, particularly on the road where they’ve played with more edge and less pressure. The Reds’ game plan heading into this contest will likely involve pushing the tempo on the bases, taking the extra bag, and putting pressure on Cleveland’s defense—especially if they can reach base early against the Guardians’ starter. Their recent success in head-to-head matchups against Cleveland should give them a confidence boost, but they’ll still need to execute in key moments to come out on top. With postseason aspirations still alive and a manageable upcoming schedule, the Reds know that every win counts, and stringing together road victories like this one could be what defines their summer surge. If the offense can get off to a quick start and the pitching staff avoids the big inning, Cincinnati has a solid chance to close the series with a win and carry momentum into their next divisional showdown.

Credit: USA TODAY/IMAGN
Cleveland Guardians MLB Preview
The Cleveland Guardians enter the series finale against the Cincinnati Reds with a 34–31 record and a determination to reclaim consistency as they navigate a competitive American League Central. After a stretch of mixed results, the Guardians remain firmly in the division race, thanks to a roster built on timely hitting, stellar defense, and a pitching staff that continues to perform at a high level despite some early-season injuries. José Ramírez remains the heartbeat of this lineup, providing switch-hitting power, leadership, and elite plate discipline that few in the league can match. He’s flanked by key contributors like Steven Kwan, who offers contact ability and speed at the top of the order, and Andrés Giménez, whose all-around game is vital to the Guardians’ style of play. This is a team that thrives on execution and efficiency—they don’t need to score in bunches, but rather manufacture runs through well-timed singles, smart baserunning, and defensive pressure. On the mound, Cleveland has seen impressive growth from its young arms, with the rotation continuing to deliver quality starts and hand leads over to one of the most reliable bullpens in baseball.
Emmanuel Clase remains a lockdown closer, featuring one of the league’s most feared cutters, and the middle-relief corps, including arms like Trevor Stephan and Sam Hentges, has shown the ability to protect narrow leads and keep games within reach. Defensively, the Guardians are among the league’s most polished units, consistently ranking near the top in team fielding percentage and advanced metrics like defensive runs saved, especially in the infield where Ramírez, Giménez, and Gabriel Arias form a sturdy core. At home in Progressive Field, Cleveland has played with confidence, boasting a 28–18 record against the spread and consistently finding ways to win close games, particularly in front of their home crowd. Their recent history against Cincinnati might not favor them statistically, but this is a team that rarely lets trends dictate performance, and their disciplined approach often allows them to outlast more aggressive opponents over the course of a game. Against the Reds, the Guardians will likely look to exploit any defensive lapses or pitching inconsistencies by applying pressure early, working counts, and forcing high pitch counts from the starter to reach the bullpen sooner. If their pitching holds and Ramírez can ignite the offense, they’re in a good position to pull out a win and secure the series at home. Manager Stephen Vogt’s calm leadership and emphasis on fundamentals have helped keep the team grounded, and his management of the bullpen and late-game strategy has paid dividends in tight contests. With the postseason picture starting to take shape, Cleveland knows that every series—and every game within it—matters. A win here would not only provide momentum heading into the next stretch but also affirm that this Guardians team is built for the long haul and capable of contending well into the summer months.
A 39-year-old who moves like a young buck. 😌#GuardsBall | #VoteGuards pic.twitter.com/UjNskvw9pK
— Cleveland Guardians (@CleGuardians) June 11, 2025
Cincinnati vs. Cleveland Prop Picks (AI)
Cincinnati vs. Cleveland Prediction (AI)

Remi, our AI sports algorithm, has been pouring over exorbitant amounts of data from every simulation between the Reds and Guardians and using recursive machine learning and impressive AI to boil down the data to a single cover probability.
The Algorithm has been most fixated on the trending factor human bettors often put on player performance factors between a Reds team going up against a possibly unhealthy Guardians team. Trends look to say the true game analytics appear to reflect a strong lean against one Vegas line specifically.
Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.
Below is our current AI Cincinnati vs Cleveland picks, computer picks Reds vs Guardians, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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MLB | 10/20 | SEA@TOR | UNLOCK THIS PICK | 2 |
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MLB | 10/20 | SEA@TOR | UNLOCK THIS PICK | 0 |
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.
Reds Betting Trends
The Cincinnati Reds have a 30–27 record against the spread (ATS) this season, indicating a solid performance in covering the run line.
Guardians Betting Trends
The Cleveland Guardians have a 28–18 record ATS, showcasing their effectiveness in covering the spread, particularly at home.
Reds vs. Guardians Matchup Trends
In their last five head-to-head matchups, the Reds have won four games against the Guardians, suggesting a recent edge in this interleague rivalry.
Cincinnati vs. Cleveland Game Info
What time does Cincinnati vs Cleveland start on June 11, 2025?
Cincinnati vs Cleveland starts on June 11, 2025 at 1:10 PM EST.
Where is Cincinnati vs Cleveland being played?
Venue: Progressive Field.
What are the opening odds for Cincinnati vs Cleveland?
Spread: Cleveland +1.5
Moneyline: Cincinnati -104, Cleveland -116
Over/Under: 8.5
What are the records for Cincinnati vs Cleveland?
Cincinnati: (35-33) | Cleveland: (34-32)
What is the AI best bet for Cincinnati vs Cleveland?
Remi's searched hard and found the best prop for this matchup: T. Friedl over 0.5 Total Bases.. Prices move—always shop for the best number.
What are Cincinnati vs Cleveland trending bets?
In their last five head-to-head matchups, the Reds have won four games against the Guardians, suggesting a recent edge in this interleague rivalry.
What are Cincinnati trending bets?
CIN trend: The Cincinnati Reds have a 30–27 record against the spread (ATS) this season, indicating a solid performance in covering the run line.
What are Cleveland trending bets?
CLE trend: The Cleveland Guardians have a 28–18 record ATS, showcasing their effectiveness in covering the spread, particularly at home.
Where can I find AI Picks for Cincinnati vs Cleveland?
See our latest MLB picks and odds pages for 2025 to compare prices before you bet.
Cincinnati vs. Cleveland Odds
Remi is pouring through loads of data on each player. In fact, anytime the Cincinnati vs Cleveland trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme hostile environments can often follow normal, predictable betting trends.
Cincinnati vs Cleveland Opening Odds
CIN Moneyline:
-104 CLE Moneyline: -116
CIN Spread: -1.5
CLE Spread: +1.5
Over/Under: 8.5
Cincinnati vs Cleveland Live Odds
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MLB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Cincinnati Reds vs. Cleveland Guardians on June 11, 2025 at Progressive Field.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
TOR@SEA | OVER 7 | 54.9% | 3 | WIN |
LAD@MIL | UNDER 7.5 | 56.6% | 6 | WIN |
TOR@NYY | OVER 8 | 54.9% | 4 | WIN |
TOR@NYY | CARLOS RODON OVER 1.5 TOTAL WALKS ALLOWED | 53.3% | 3 | WIN |
NYY@TOR | OVER 7.5 | 54.8% | 2 | WIN |
LAD@PHI | OVER 7 | 53.8% | 3 | WIN |
SD@CHC | CHC -109 | 53.8% | 3 | WIN |
SD@CHC | OVER 7.5 | 54.5% | 4 | LOSS |
SD@CHC | CHC -111 | 54.8% | 4 | LOSS |
CIN@LAD | SHOHEI OHTANI OVER 1.5 BASES | 53.5% | 3 | WIN |
BOS@NYY | OVER 7 | 53.8% | 3 | LOSS |
CIN@LAD | ELLY DE LA CRUZ OVER 0.5 BASES | 54.4% | 4 | LOSS |
ARI@SD | SD -131 | 57.3% | 4 | WIN |
DET@BOS | BOS -115 | 56.4% | 5 | WIN |
NYM@CHC | NYM -110 | 54.1% | 3 | WIN |
HOU@ATH | ATH +118 | 50.8% | 4 | WIN |
NYM@CHC | OVER 7 | 54.5% | 3 | WIN |
STL@SF | OVER 7.5 | 55.9% | 5 | LOSS |
KC@LAA | TYLER TOLBERT UNDER 1.5 BASES | 54.4% | 4 | WIN |
MIL@SD | UNDER 9 | 54.7% | 4 | WIN |
MIA@PHI | KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS | 53.3% | 3 | WIN |
WAS@NYM | OVER 8.5 | 56.1% | 6 | LOSS |
LAA@COL | COL +108 | 50.5% | 3 | WIN |
TOR@KC | UNDER 9 | 54.7% | 4 | LOSS |
SEA@KC | KC +1.5 | 62.3% | 5 | LOSS |
NYY@MIN | OVER 9 | 55.1% | 4 | WIN |
MIA@COL | OVER 10.5 | 55.0% | 4 | WIN |
MIA@COL | AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS | 54.3% | 4 | WIN |
SEA@KC | BOBBY WITT UNDER 0.5 SINGLES | 54.4% | 4 | LOSS |
PHI@LAD | LAD -113 | 54.7% | 4 | LOSS |
NYY@BOS | OVER 7.5 | 54.3% | 3 | WIN |
KC@PHI | PHI -130 | 58.3% | 4 | WIN |
LAD@SF | OVER 7.5 | 54.7% | 4 | LOSS |
NYM@PHI | PHI -122 | 55.6% | 4 | WIN |
KC@CLE | KC -104 | 52.0% | 3 | WIN |
CIN@SD | JAKE CRONEWORTH OVER 0.5 HITS | 53.1% | 3 | WIN |
WAS@MIA | MIA -123 | 55.2% | 4 | LOSS |
LAA@KC | UNDER 9.5 | 54.9% | 3 | WIN |
TEX@ARI | UNDER 9 | 54.2% | 4 | WIN |
SF@COL | UNDER 11.5 | 56.4% | 6 | LOSS |
SF@COL | RAFAEL DEVERS OVER 1.5 BASES | 56.1% | 6 | WIN |
MIA@WAS | WAS -110 | 54.4% | 4 | WIN |
NYM@DET | OVER 8.5 | 54.5% | 4 | WIN |
TEX@ARI | UNDER 9.5 | 56.4% | 6 | WIN |
TEX@ARI | ALEJANDRO OSUNA UNDER 1.5 BASES | 54.1% | 4 | LOSS |
ATL@CHC | CHC -116 | 55.1% | 3 | WIN |
PHI@MIL | OVER 8.5 | 55.0% | 3 | WIN |
ARI@LAD | SHOHEI OHTANI OVER 2.5 BASES | 54.2% | 4 | WIN |
SEA@CLE | CLE +1.5 | 57.2% | 3 | WIN |
CHC@SF | CHC -105 | 54.1% | 4 | LOSS |
NYY@CHW | RYAN MCMAHON OVER 0.5 BASES | 54.1% | 4 | WIN |