Reds vs. Guardians
Prediction, Odds & Props
Jun 10 | MLB AI Picks

Updated: 2025-06-08T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Cincinnati Reds and Cleveland Guardians face off in the second game of their Ohio Cup series on Tuesday, June 10, 2025, at Progressive Field. With both teams aiming to improve their standings, this matchup features a compelling duel between Reds’ left-hander Andrew Abbott and Guardians’ right-hander Slade Cecconi.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Jun 10, 2025

Start Time: 6:40 PM EST​

Venue: Progressive Field​

Guardians Record: (34-31)

Reds Record: (34-33)

OPENING ODDS

CIN Moneyline: -103

CLE Moneyline: -117

CIN Spread: +1.5

CLE Spread: -1.5

Over/Under: 8

CIN
Betting Trends

  • The Reds have seen the game total go under in 32 of their last 53 games, indicating a trend towards lower-scoring affairs.

CLE
Betting Trends

  • The Guardians have hit the moneyline in 22 of their last 38 games, showcasing a solid performance in recent matchups.

MATCHUP TRENDS

  • Cincinnati has consistently hit the game total under in 16 of their last 20 games, while Cleveland has demonstrated strength on the moneyline, winning 23 of their last 36 games.

CIN vs. CLE
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: C. Santana over 0.5 Totakl Bases.

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Cincinnati vs Cleveland Prediction & Odds:
Free MLB Betting Insights for 6/10/25

Tuesday’s Ohio Cup clash between the Cincinnati Reds and the Cleveland Guardians at Progressive Field promises to be a tense, evenly matched showdown between two intrastate rivals on divergent trajectories in their respective divisions, with the Guardians looking to keep pace atop the AL Central while the Reds seek to claw their way back into NL Central contention. The Reds come in with a 30–33 record and one of the more underrated pitching weapons in the National League in lefty Andrew Abbott, who has been lights-out with a 5–1 record, 2.18 ERA, and a growing reputation for working deep into games while keeping the ball on the ground. He’ll take the mound against Slade Cecconi, a right-hander still finding consistency with a 1–2 record and 4.87 ERA, but one who has flashed enough stuff to keep the Guardians competitive if he limits hard contact and avoids early pitch count problems. Offensively, Cincinnati has leaned heavily on the electricity of Elly De La Cruz, who leads the club in both home runs (12) and RBIs (43), while Austin Hays brings balance with a .303 batting average, giving the Reds a mix of speed, pop, and situational hitting that’s allowed them to hang tough in tight games even as their bullpen has occasionally faltered. On the other side, Cleveland enters at 33–28 with a team that hasn’t been dominant in any one statistical category but remains gritty and opportunistic, thanks to a combination of timely hitting, steady fielding, and a team-first approach that has them winning two out of every three games recently.

The Guardians have hit 63 home runs as a team and are batting .234 overall, relying on pressure hitting and intelligent base running to manufacture runs in close contests, particularly at home where they’ve had success controlling tempo and preventing big innings. The total for this matchup trends toward the under, which aligns with the Reds’ recent betting profile, having hit the under in 16 of their last 20 games, thanks in part to strong starting pitching and quieter middle innings. Cleveland, meanwhile, has hit the moneyline in 22 of their last 38 and continues to find value in grinding out low-scoring games and turning leads over to their bullpen, which has been more reliable than Cincinnati’s over the past month. Expect a matchup where early scoring is critical—if Abbott finds a rhythm and De La Cruz can spark the Reds’ lineup, Cincinnati could control the game with a few timely blasts, but if Cecconi can settle in and Cleveland’s offense executes small ball effectively, the Guardians have every chance to protect their home field. The betting lines may slightly favor the Guardians based on recent home performance, but with Abbott on the mound and the Reds’ offense heating up, this game is likely to go down to the wire in a 4–3 or 3–2 type finish, with bullpen execution and defensive sharpness ultimately determining the outcome.

Cincinnati Reds MLB Preview

The Cincinnati Reds enter Tuesday’s Ohio Cup matchup against the Cleveland Guardians with a 30–33 record and a clear sense of urgency as they seek to climb out of the middle of the NL Central standings, anchored by the breakout performance of left-hander Andrew Abbott, who has been one of the most consistent arms in their rotation this season. Abbott, with a 5–1 record and a sparkling 2.18 ERA, has emerged as a legitimate frontline presence, commanding both sides of the plate with confidence and effectively using his changeup to keep right-handed hitters off balance while limiting home run damage—an especially important trait in a park like Progressive Field that can favor power hitters in warmer months. Offensively, the Reds are led by Elly De La Cruz, who combines highlight-reel speed with legitimate power, pacing the team in both home runs (12) and RBIs (43), and providing a dynamic top-of-the-order threat capable of turning a game on its head in a single inning. Supporting him is veteran outfielder Austin Hays, whose .303 average and disciplined approach have given Cincinnati the kind of consistent at-bats that help bridge rallies between the team’s more boom-or-bust bats. Collectively, the Reds’ .243 team batting average and 64 home runs reflect a lineup that can do damage in spurts but also has endured stretches of inconsistency, particularly in the late innings when bullpen support has wavered.

Defensively, the team has shown improvement with tighter infield play and outfield range that supports their pitching staff, but mental lapses and occasional control issues from the bullpen have allowed leads to slip away, which will need to be addressed against a Guardians club that capitalizes on mistakes. From a betting perspective, Cincinnati has been one of the league’s strongest under teams recently, hitting the under in 16 of their last 20 games thanks largely to solid starting pitching and low run support during middle innings, and that trend could continue if Abbott delivers another quality start and the offense doesn’t break out until late. For the Reds to steal this road game, Abbott will need to navigate a Cleveland lineup that doesn’t strike out much and plays situational baseball effectively, meaning command and soft contact will be essential. If De La Cruz and Hays can ignite the offense early and pressure Slade Cecconi into high-leverage innings with runners on base, Cincinnati could create just enough offense to back their ace and hand the game over to the bullpen with a lead. However, success will depend heavily on limiting Cleveland’s chances to manufacture runs through walks, steals, and bloop hits—the kinds of sequences that have hurt the Reds in tight games all season. If they stay sharp and get the performance expected from Abbott, Cincinnati has a real shot to take control early and finish with a much-needed 4–2 or 3–1 road victory.

The Cincinnati Reds and Cleveland Guardians face off in the second game of their Ohio Cup series on Tuesday, June 10, 2025, at Progressive Field. With both teams aiming to improve their standings, this matchup features a compelling duel between Reds’ left-hander Andrew Abbott and Guardians’ right-hander Slade Cecconi. Cincinnati vs Cleveland AI Prediction: Free MLB Betting Insights for Jun 10. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Cleveland Guardians MLB Preview

The Cleveland Guardians return home for the second game of the Ohio Cup series against the Cincinnati Reds with a 33–28 record and a growing reputation for grinding out wins through solid pitching, timely hitting, and a fundamentally sound brand of baseball that has kept them near the top of the AL Central. Starting pitcher Slade Cecconi takes the mound for Cleveland with a 1–2 record and a 4.87 ERA, and while his season has been marked by inconsistency, he’s shown flashes of upside with a fastball that can reach the mid-90s and a developing slider that, when located well, generates weak contact and keeps hitters guessing through the first two trips in the order. The Guardians’ pitching staff as a whole has been able to manage close games effectively, especially at home, and their bullpen has provided stability late in games, allowing manager Stephen Vogt to deploy matchup-specific strategies to protect leads in the sixth inning or later. Offensively, Cleveland’s .234 team batting average and 63 home runs may not jump off the page, but the team’s ability to capitalize on base-running opportunities and put the ball in play consistently gives them an edge in low-scoring contests, particularly when facing high-strikeout starters like Andrew Abbott. Key contributors like José Ramírez and Josh Naylor have continued to deliver in pressure spots, while the supporting cast, including Andrés Giménez and Will Brennan, has chipped in with key two-out hits that have swung the outcome of multiple games.

The Guardians’ defensive execution has also been a major asset, with well-timed shifts, strong infield communication, and outfield range that supports the pitching staff by minimizing extra-base hits in the gaps, especially in home games where they’ve consistently limited opponents’ big innings. From a betting perspective, Cleveland has hit the moneyline in 22 of their last 38 games and 23 of their last 36 overall, reflecting their recent run of strong play and ability to stay competitive even against higher-ceiling opponents like Cincinnati when Abbott is pitching. The Guardians have thrived in games with tight margins, and with a Reds team that has struggled to produce consistent offense against mid-tier right-handers like Cecconi, Cleveland’s blueprint for victory will rely on early pitch efficiency, capitalizing on runners in scoring position, and handing off a lead to the bullpen without allowing Cincinnati’s speed game or power bats to flip momentum. If Cecconi can survive the first four innings without allowing multiple runs and the Guardians can scratch across three to four runs through smart base running and contact hitting, they have a strong chance to take a 2–0 series lead and continue their ascent as a legitimate contender in the American League. A 4–3 or 5–2 type of win is within reach if the Guardians execute the way they have over the last three weeks at Progressive Field.

Cincinnati vs. Cleveland Prop Picks (AI)

Remi is pouring through loads of data on each team. In fact, anytime the Reds and Guardians play there’s always several intriguing trends to key in on. Not to mention games played at Progressive Field in Jun seemingly never follow normal, predictable patterns.
Remi's searched hard and found the best prop for this matchup: C. Santana over 0.5 Totakl Bases.

Cincinnati vs. Cleveland Prediction (AI)

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Remi, our AI sports wizard, has been pouring over exorbitant amounts of data from every simulation between the Reds and Guardians and using recursive machine learning and industry leading AI to crunch the data to a single cover probability.

Interestingly enough, the data has been most focused on the growing emphasis human bettors often put on Cleveland’s strength factors between a Reds team going up against a possibly deflated Guardians team. Trends look to say the true game analytics appear to reflect a strong lean against one Vegas line specifically.

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Below is our current AI Cincinnati vs Cleveland picks, computer picks Reds vs Guardians, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

Reds Betting Trends

The Reds have seen the game total go under in 32 of their last 53 games, indicating a trend towards lower-scoring affairs.

Guardians Betting Trends

The Guardians have hit the moneyline in 22 of their last 38 games, showcasing a solid performance in recent matchups.

Reds vs. Guardians Matchup Trends

Cincinnati has consistently hit the game total under in 16 of their last 20 games, while Cleveland has demonstrated strength on the moneyline, winning 23 of their last 36 games.

Cincinnati vs. Cleveland Game Info

Cincinnati vs Cleveland starts on June 10, 2025 at 6:40 PM EST.

Spread: Cleveland -1.5
Moneyline: Cincinnati -103, Cleveland -117
Over/Under: 8

Cincinnati: (34-33)  |  Cleveland: (34-31)

Remi's searched hard and found the best prop for this matchup: C. Santana over 0.5 Totakl Bases.. Prices move—always shop for the best number.

Cincinnati has consistently hit the game total under in 16 of their last 20 games, while Cleveland has demonstrated strength on the moneyline, winning 23 of their last 36 games.

CIN trend: The Reds have seen the game total go under in 32 of their last 53 games, indicating a trend towards lower-scoring affairs.

CLE trend: The Guardians have hit the moneyline in 22 of their last 38 games, showcasing a solid performance in recent matchups.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

Cincinnati vs. Cleveland Odds

AI algorithm Remi is pouring through loads of data on each player. In fact, anytime the Cincinnati vs Cleveland trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme temps seemingly never follow normal, predictable betting trends.

Cincinnati vs Cleveland Opening Odds

CIN Moneyline: -103
CLE Moneyline: -117
CIN Spread: +1.5
CLE Spread: -1.5
Over/Under: 8

Cincinnati vs Cleveland Live Odds

Games PTS ML SPR O/U
Sep 28, 2025 3:06PM EDT
Baltimore Orioles
New York Yankees
9/28/25 3:06PM
Orioles
Yankees
+160
-195
+1.5 (-125)
-1.5 (+105)
O 9 (+100)
U 9 (-120)
Sep 28, 2025 3:06PM EDT
Colorado Rockies
San Francisco Giants
9/28/25 3:06PM
Rockies
Giants
+240
-300
+1.5 (+115)
-1.5 (-140)
O 7.5 (-105)
U 7.5 (-115)
Sep 28, 2025 3:06PM EDT
Minnesota Twins
Philadelphia Phillies
9/28/25 3:06PM
Twins
Phillies
+165
-200
+1.5 (-120)
-1.5 (+100)
O 8.5 (+100)
U 8.5 (-120)
Sep 28, 2025 3:06PM EDT
Chicago White Sox
Washington Nationals
9/28/25 3:06PM
White Sox
Nationals
+100
-120
-1.5 (+165)
+1.5 (-200)
O 8.5 (-120)
U 8.5 (+100)
Sep 28, 2025 3:08PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/28/25 3:08PM
Rays
Blue Jays
+160
-195
+1.5 (-130)
-1.5 (+110)
O 7.5 (-115)
U 7.5 (-105)
Sep 28, 2025 3:10PM EDT
Los Angeles Dodgers
Seattle Mariners
9/28/25 3:10PM
Dodgers
Mariners
-105
-115
-1.5 (+160)
+1.5 (-195)
O 8 (-105)
U 8 (-115)
Sep 28, 2025 3:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/28/25 3:11PM
Reds
Brewers
+120
-145
+1.5 (-140)
-1.5 (+115)
O 7.5 (-110)
U 7.5 (-110)
Sep 28, 2025 3:11PM EDT
New York Mets
Miami Marlins
9/28/25 3:11PM
Mets
Marlins
-125
+105
-1.5 (+135)
+1.5 (-165)
O 8.5 (+100)
U 8.5 (-120)
Sep 28, 2025 3:16PM EDT
Pittsburgh Pirates
Atlanta Braves
9/28/25 3:16PM
Pirates
Braves
+170
-205
+1.5 (-125)
-1.5 (+105)
O 7.5 (-110)
U 7.5 (-110)
Sep 28, 2025 3:20PM EDT
St Louis Cardinals
Chicago Cubs
9/28/25 3:20PM
Cardinals
Cubs
 
-170
 
-1.5 (+140)
O 8 (-115)
U 8 (-105)
Sep 30, 2025 2:30PM EDT
San Diego Padres
Chicago Cubs
9/30/25 2:30PM
Padres
Cubs
+101
-123
pk
pk

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Cincinnati Reds vs. Cleveland Guardians on June 10, 2025 at Progressive Field.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
ARI@SD SD -131 57.3% 4 WIN
DET@BOS BOS -115 56.4% 5 WIN
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS