Guardians vs. Yankees
Prediction, Odds & Props
Jun 05 | MLB AI Picks

Updated: 2025-06-03T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Cleveland Guardians (33–27) travel to Yankee Stadium on Thursday, June 5, 2025, for the finale of their three-game series against the New York Yankees (36–22). The Yankees look to bounce back from a disappointing 4–0 loss on Wednesday, while Cleveland aims to strike early and extend their competitive stretch.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Jun 05, 2025

Start Time: 7:05 PM EST​

Venue: Yankee Stadium​

Yankees Record: (37-23)

Guardians Record: (33-27)

OPENING ODDS

CLE Moneyline: +217

NYY Moneyline: -267

CLE Spread: +1.5

NYY Spread: -1.5

Over/Under: 8.5

CLE
Betting Trends

  • Cleveland has gone 6–4 ATS over its last 10 games and 3–7 as underdogs of +216 or more, showing resolve but also inconsistencies at higher spreads.

NYY
Betting Trends

  • The Yankees are 1–4 ATS in their last 5 home games and 26–28 ATS overall this season, indicating underwhelming performance at Yankee Stadium.

MATCHUP TRENDS

  • Despite both teams’ top offenses, the total has gone UNDER 8.5 in 4 of New York’s last 5 home games. Today’s O/U is set at 8.5, suggesting expectations for another lean scoring night.

CLE vs. NYY
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: J. Chisholm over 0.5 Total Bases.

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Cleveland vs New York Yankees Prediction & Odds:
Free MLB Betting Insights for 6/5/25

The Cleveland Guardians and New York Yankees wrap up their three-game series at Yankee Stadium on Thursday, June 5, 2025, in a matchup that pits two playoff-caliber teams with differing recent momentum. The Guardians, sitting at 33–27, bounced back from a quiet offensive stretch to blank the Yankees 4–0 on Wednesday, delivering a well-rounded performance behind strong pitching and timely contact hitting. Slade Cecconi is scheduled to start for Cleveland, a right-hander who’s posted a 5.28 ERA with some recent improvement, but still remains vulnerable to deep lineups and needs to keep the ball in the park. Cleveland’s offense will look to maintain balance, with José Ramírez (.330 average, 11 HR) continuing to lead the charge, flanked by Steven Kwan’s consistent bat (.308 average) and the emerging power of Kyle Manzardo. On the other side, the Yankees sit at 36–22 and have struggled at home lately, going 1–4 ATS in their last five games at Yankee Stadium, despite boasting one of the league’s most dangerous lineups. New York turns to ace Max Fried, who enters with a dominant 7–1 record and a sparkling 1.92 ERA, bringing command and poise that should make him a strong counter to Cleveland’s small-ball approach.

Offensively, Aaron Judge continues to rake at an MVP pace with a .387 average, 21 home runs, and 47 RBIs, supported by Paul Goldschmidt (.327 average) and Giancarlo Stanton’s looming power. The Yankees have been inconsistent in the bullpen due to injuries, with closer Luke Weaver sidelined and Fernando Cruz stepping in as a stopgap before Devin Williams reassumed the ninth-inning role. While New York’s big bats can change a game instantly, their recent home scoring trends suggest they’ve been more reliant on sequencing and base hits rather than all-or-nothing swings. The total for this game is set at 8.5, a number that reflects respect for Fried’s dominance and the potential for another low-scoring contest if Cecconi can work effectively through the first four innings. Cleveland’s bullpen has been heavily used—ranking third in innings pitched this season—but continues to deliver, and should be ready to support Cecconi early if needed. The key battle will revolve around how Cleveland handles Max Fried’s early command and whether they can force the Yankees into mid-game bullpen usage. For the Yankees, capitalizing on scoring chances when runners are in position and maintaining sharp defense will be essential if they want to regain control and secure a series win. This game is likely to hinge on who controls the tempo in the first five innings and which team avoids high-leverage mistakes in the late frames. With playoff implications and strong individual performances on both sides, this finale offers a critical tone-setter as both clubs enter the heart of the summer schedule.

Cleveland Guardians MLB Preview

The Cleveland Guardians head into Thursday’s series finale at Yankee Stadium with renewed confidence following a sharp 4–0 win in Game 2, a performance that snapped a quiet stretch of offensive struggles and highlighted their potential when both pitching and timely hitting click. With a 33–27 record, the Guardians have quietly remained in postseason contention in the AL Central and continue to rely on a blend of elite contact hitters and emerging young talent to stay competitive. Slade Cecconi is expected to start, and while he brings a 5.28 ERA and hasn’t yet proven the ability to consistently work deep into games, his recent outings have shown flashes of growth, particularly in pitch sequencing and limiting big innings. Cleveland’s lineup is led by perennial MVP candidate José Ramírez, who enters with a .330 average and 11 home runs, providing the combination of power, speed, and plate discipline that drives the Guardians’ offense. Alongside him, Steven Kwan continues to deliver high-contact consistency with a .308 average and solid baserunning instincts, while Kyle Manzardo and Carlos Santana are starting to round into form and give the lineup more depth.

The Guardians thrive on playing fundamentally sound baseball—putting the ball in play, stealing extra bases, and avoiding defensive lapses—which has allowed them to stay within striking distance even in games where they trail early. Their bullpen has been one of the most frequently used in baseball but has held up well under the workload, maintaining top-ten marks in both ERA and WHIP thanks to the efforts of arms like Emmanuel Clase and Scott Barlow. The key for Cleveland will be to keep the game close through the first five innings and then hand it off to their relievers with a manageable margin, while trying to scratch across runs against Yankees ace Max Fried, who has been lights-out with a 1.92 ERA and 7–1 record. Given New York’s recent bullpen uncertainty due to injuries and the Guardians’ ability to manufacture offense in unconventional ways, Cleveland has a legitimate chance to steal the series if they can stay aggressive and disciplined at the plate. A strong start from Cecconi, clean defensive execution, and opportunistic offense will be the formula as they look to return to Ohio with another statement road win and a potential playoff tiebreaker in hand. This game presents a key opportunity for Cleveland to show they can compete with elite teams away from home and continue their steady climb in the American League standings.

The Cleveland Guardians (33–27) travel to Yankee Stadium on Thursday, June 5, 2025, for the finale of their three-game series against the New York Yankees (36–22). The Yankees look to bounce back from a disappointing 4–0 loss on Wednesday, while Cleveland aims to strike early and extend their competitive stretch. Cleveland vs New York Yankees AI Prediction: Free MLB Betting Insights for Jun 05. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

New York Yankees Yankees MLB Preview

The New York Yankees return to Yankee Stadium on Thursday, June 5, 2025, looking to reclaim control in their series finale against the Cleveland Guardians after suffering a surprising 4–0 loss in Game 2, one of their few shutout defeats of the season and a reflection of recent home-field inconsistencies. At 36–22, the Yankees remain near the top of the AL East, but their 1–4 ATS record in their last five home games has raised questions about their ability to consistently execute in the Bronx despite the immense power and depth in their lineup. Leading the charge is Aaron Judge, who continues to be the most dangerous hitter in baseball with a jaw-dropping .387 average, 21 home runs, and a .485 OBP, providing both power and plate discipline in every at-bat, while Paul Goldschmidt (.327 average) has proven to be a key veteran addition, providing balance and reliability in the middle of the order. The Yankees’ offensive arsenal doesn’t end there, as Giancarlo Stanton remains a looming presence with his ability to change games in a single swing, even though his production has fluctuated in recent weeks. On the mound, they’ll send ace Max Fried (7–1, 1.92 ERA), whose elite command, soft contact rates, and postseason-like poise give New York a definitive edge in any game he starts, particularly at home where he’s been nearly untouchable.

Fried will be tasked with silencing a Guardians lineup that thrives on contact and small-ball execution, so quick innings and first-pitch strikes will be critical if he’s to work deep and keep the bullpen out of early trouble. New York’s bullpen has been reshuffled due to injuries, with Luke Weaver sidelined and Fernando Cruz taking on high-leverage roles before the recently returned Devin Williams began to reclaim closer duties, though there’s still a need for consistent middle-inning bridge work. Manager Aaron Boone will rely on Fried to set the tone early while hoping his offense rebounds from a rare scoreless effort, particularly by capitalizing on mistakes from Cleveland starter Slade Cecconi, who enters with a 5.28 ERA and a tendency to get hit hard by disciplined hitters. The Yankees must focus on stringing together quality at-bats and executing with runners in scoring position, as their tendency to rely on the long ball can sometimes lead to droughts when the ball isn’t flying. Defensively, the Yankees remain sharp, anchored by solid infield play and athleticism across the outfield, but a clean sheet will be needed to support what’s expected to be a tight, low-scoring game. With the series on the line, New York will aim to lean on its ace, bounce back with early offense, and use the final game of the homestand to reassert themselves before heading into a critical stretch of summer baseball that will test their depth and resolve in the American League playoff picture.

Cleveland vs. New York Yankees Prop Picks (AI)

AI algorithm Remi is pouring through loads of stats on each line. In fact, anytime the Guardians and Yankees play there’s always several intriguing observations to key in on. Not to mention games played at Yankee Stadium in Jun rarely follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: J. Chisholm over 0.5 Total Bases.

Cleveland vs. New York Yankees Prediction (AI)

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Remi, our AI sports wizard, has been pouring over exorbitant amounts of data from every angle between the Guardians and Yankees and using recursive machine learning and cutting-edge AI to examine the data to a single cover probability.

Oddly enough, we’ve seen the AI has been most keyed in on the growing weight human bettors often put on player performance factors between a Guardians team going up against a possibly unhealthy Yankees team. We’ve found the true game analytics might reflect a moderate lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI Cleveland vs New York Yankees picks, computer picks Guardians vs Yankees, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
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Guardians Betting Trends

Cleveland has gone 6–4 ATS over its last 10 games and 3–7 as underdogs of +216 or more, showing resolve but also inconsistencies at higher spreads.

Yankees Betting Trends

The Yankees are 1–4 ATS in their last 5 home games and 26–28 ATS overall this season, indicating underwhelming performance at Yankee Stadium.

Guardians vs. Yankees Matchup Trends

Despite both teams’ top offenses, the total has gone UNDER 8.5 in 4 of New York’s last 5 home games. Today’s O/U is set at 8.5, suggesting expectations for another lean scoring night.

Cleveland vs. New York Yankees Game Info

Cleveland vs New York Yankees starts on June 05, 2025 at 7:05 PM EST.

Spread: New York Yankees -1.5
Moneyline: Cleveland +217, New York Yankees -267
Over/Under: 8.5

Cleveland: (33-27)  |  New York Yankees: (37-23)

Remi's searched hard and found the best prop for this matchup: J. Chisholm over 0.5 Total Bases.. Prices move—always shop for the best number.

Despite both teams’ top offenses, the total has gone UNDER 8.5 in 4 of New York’s last 5 home games. Today’s O/U is set at 8.5, suggesting expectations for another lean scoring night.

CLE trend: Cleveland has gone 6–4 ATS over its last 10 games and 3–7 as underdogs of +216 or more, showing resolve but also inconsistencies at higher spreads.

NYY trend: The Yankees are 1–4 ATS in their last 5 home games and 26–28 ATS overall this season, indicating underwhelming performance at Yankee Stadium.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

Cleveland vs. New York Yankees Odds

Remi is pouring through mountains of data points on each team. In fact, anytime the Cleveland vs New York Yankees trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme hostile environments seemingly never follow normal, predictable patterns.

Cleveland vs New York Yankees Opening Odds

CLE Moneyline: +217
NYY Moneyline: -267
CLE Spread: +1.5
NYY Spread: -1.5
Over/Under: 8.5

Cleveland vs New York Yankees Live Odds

Games PTS ML SPR O/U
In Progress
Minnesota Twins
Philadelphia Phillies
In Progress
Twins
Phillies
5
0
-375
+260
-4.5 (+265)
+4.5 (-375)
O 5.5 (-115)
U 5.5 (-115)
In Progress
Cincinnati Reds
Milwaukee Brewers
In Progress
Reds
Brewers
6
1
-850
+510
-4.5 (+105)
+4.5 (-140)
O 13.5 (+105)
U 13.5 (-140)
In Progress
Texas Rangers
Cleveland Guardians
In Progress
Rangers
Guardians
2
2
+125
-165
+1.5 (-300)
-1.5 (+215)
O 7.5 (+110)
U 7.5 (-145)
In Progress
Pittsburgh Pirates
Atlanta Braves
In Progress
Pirates
Braves
1
1
+120
-160
+1.5 (-245)
-1.5 (+180)
O 6.5 (-110)
U 6.5 (-120)
Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
+130
-155
+1.5 (-170)
-1.5 (+140)
O 7.5 (-105)
U 7.5 (-115)
Sep 27, 2025 9:39PM EDT
Houston Astros
Los Angeles Angels
9/27/25 9:39PM
Astros
Angels
-145
+120
-1.5 (+115)
+1.5 (-140)
O 9 (-110)
U 9 (-110)
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
+110
-130
+1.5 (-200)
-1.5 (+165)
O 7 (+100)
U 7 (-120)
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
+100
-120
-1.5 (+155)
+1.5 (-190)
O 10 (-115)
U 10 (-105)
Sep 28, 2025 3:06PM EDT
Baltimore Orioles
New York Yankees
9/28/25 3:06PM
Orioles
Yankees
+140
-170
+1.5 (-125)
-1.5 (+105)
O 9.5 (+100)
U 9.5 (-120)
Sep 28, 2025 3:06PM EDT
Colorado Rockies
San Francisco Giants
9/28/25 3:06PM
Rockies
Giants
+240
-300
+1.5 (+115)
-1.5 (-140)
O 7.5 (-110)
U 7.5 (-110)
Sep 28, 2025 3:06PM EDT
Minnesota Twins
Philadelphia Phillies
9/28/25 3:06PM
Twins
Phillies
+165
-200
+1.5 (-120)
-1.5 (+100)
O 8.5 (+100)
U 8.5 (-120)
Sep 28, 2025 3:06PM EDT
Chicago White Sox
Washington Nationals
9/28/25 3:06PM
White Sox
Nationals
-105
-115
-1.5 (+155)
+1.5 (-190)
O 8.5 (-120)
U 8.5 (+100)
Sep 28, 2025 3:08PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/28/25 3:08PM
Rays
Blue Jays
+160
-195
+1.5 (-120)
-1.5 (+100)
O 8 (-105)
U 8 (-115)
Sep 28, 2025 3:10PM EDT
Los Angeles Dodgers
Seattle Mariners
9/28/25 3:10PM
Dodgers
Mariners
-110
-110
-1.5 (+155)
+1.5 (-190)
O 8.5 (+100)
U 8.5 (-120)
Sep 28, 2025 3:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/28/25 3:11PM
Reds
Brewers
+130
-155
+1.5 (-150)
-1.5 (+125)
O 7.5 (-110)
U 7.5 (-110)

MLB Past Picks

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We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Cleveland Guardians vs. New York Yankees Yankees on June 05, 2025 at Yankee Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
ARI@SD SD -131 57.3% 4 WIN
DET@BOS BOS -115 56.4% 5 WIN
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS