White Sox vs. Orioles
Prediction, Odds & Props
Jun 01 | MLB AI Picks

Updated: 2025-05-30T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

On June 1, 2025, the Chicago White Sox (18–39) will face the Baltimore Orioles (20–36) at Oriole Park at Camden Yards. Both teams are looking to gain momentum as they approach the midseason mark.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Jun 01, 2025

Start Time: 1:35 PM EST​

Venue: Oriole Park at Camden Yards​

Orioles Record: (21-36)

White Sox Record: (18-40

OPENING ODDS

CHW Moneyline: +142

BAL Moneyline: -170

CHW Spread: +1.5

BAL Spread: -1.5

Over/Under: 9

CHW
Betting Trends

  • The White Sox have covered the run line in 4 of their last 5 games, showing a profit of 2.52 units.

BAL
Betting Trends

  • The Orioles have a 5–5 record against the spread over their past 10 games, reflecting inconsistent performance in covering the run line at home.

MATCHUP TRENDS

  • The Orioles have won 4 of their last 5 series at Camden Yards against the White Sox, and the last 5 home games between these teams have gone over the total.

CHW vs. BAL
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: A. Benintendi over 0.5 Total Bases.

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Chicago White Sox vs Baltimore Prediction & Odds:
Free MLB Betting Insights for 6/1/25

The June 1, 2025 matchup between the Chicago White Sox and the Baltimore Orioles at Oriole Park at Camden Yards pits two struggling American League clubs against one another, both looking to spark some midseason momentum after slow starts. The Orioles enter the game with a 20–36 record, having shown flashes of offensive life but lacking consistency in both run prevention and late-game execution, while the White Sox are slightly worse at 18–39 but have recently covered the run line in four of their last five games and seem to be finding a bit of rhythm. Baltimore’s historical advantage at home over the White Sox is notable—they’ve won four of the last five series against them at Camden Yards, and the last five home games between the two have all gone over the total, suggesting a high-scoring affair could be on tap. Offensively, Baltimore leans on the recent production of Ryan O’Hearn, who has been swinging a hot bat, and they’ll look to him again to help jumpstart a lineup that has struggled to generate consistent pressure on opposing pitchers. The Orioles have been average against the spread lately, going 5–5 over their last 10 games, a fair indicator of their volatility, especially given defensive lapses and an underwhelming bullpen that has allowed several late-game leads to slip.

Meanwhile, the White Sox, though near the bottom of the AL Central, have found some life through the bat of Miguel Vargas, who leads the team with eight home runs and 26 RBIs, and the contact-hitting of Chase Meidroth, who’s hitting .274 and helping keep rallies alive. Chicago’s offense has been limited in power but has shown grit in recent games, aided by improved run prevention and fewer defensive errors. Adrian Houser is expected to start on the mound for the White Sox and brings valuable experience that could help stabilize their rotation and keep the game close. With betting odds placing Baltimore as a -169 favorite and Chicago at +142 underdogs, oddsmakers acknowledge the Orioles’ home-field edge but also the White Sox’s recent trend of outperforming expectations. With an over/under set at 9 runs and both teams showing signs of offensive activity—combined with shaky pitching—the game could open up in the middle innings and come down to bullpen efficiency and clutch hitting. For the White Sox, continuing their recent surge against the spread and avoiding big innings defensively will be key to a potential upset. For the Orioles, jumping on Houser early and holding a lead through nine innings will be the formula for victory. This matchup may not carry postseason stakes, but for two rebuilding franchises desperate for consistency and momentum, every win matters—and this one could serve as a launching point into a more respectable summer stretch for whichever club manages to execute better in the small details.

Chicago White Sox White Sox MLB Preview

The Chicago White Sox enter their June 1, 2025 road matchup against the Baltimore Orioles with a 18–39 record that underscores a season full of inconsistency, but recent signs of life suggest a potential turnaround may be brewing. The White Sox have covered the run line in four of their last five games, showing a profit of 2.52 units and finally displaying competitive fire after spending most of the season stuck in last place in the AL Central. Much of the recent improvement has been fueled by the emergence of Miguel Vargas as a power threat, leading the team with eight home runs and 26 RBIs, while Chase Meidroth continues to swing a consistent bat, batting .274 and helping to keep the offense afloat with timely contact and hustle plays. Despite a mostly underwhelming offensive season, the White Sox lineup has started stringing together better at-bats, especially against average or struggling pitching, which gives them hope heading into a game against an Orioles staff that has been far from dominant. Expected starter Adrian Houser brings some veteran stability to the rotation and will look to build on recent outings that have shown better command and fewer high-leverage jams.

Houser’s role is especially crucial given the bullpen’s spotty track record, as the White Sox have blown several games in the late innings due to walks, missed spots, and an inability to miss bats. However, the bullpen has quietly improved over the past week, delivering more scoreless innings and doing just enough to support the offense’s recent efforts. Defensively, the team has trimmed down errors and unforced mistakes, finally giving their pitchers more of a chance to keep games manageable. While the White Sox have struggled historically at Camden Yards—losing four of their last five series there—they enter this matchup with a different energy and an underdog’s sense of urgency. Manager Pedro Grifol has kept the clubhouse focused on incremental progress, and that approach is starting to reflect in tighter, more competitive games. If the White Sox can continue their recent ATS trend and execute early against Baltimore’s starting pitcher, they’ll be in position to put pressure on a shaky Orioles bullpen and exploit defensive gaps. Their keys to victory will include an effective start from Houser, continued production from Vargas and Meidroth, and a clean defensive performance to avoid giving away extra outs. With oddsmakers listing them as +142 underdogs, the White Sox are in familiar territory—and they’ve recently shown that when the expectations are low, they can punch above their weight. A road win here wouldn’t drastically alter the trajectory of their season, but it would mark another small step forward for a young and evolving roster beginning to find competitive rhythm in a long season.

On June 1, 2025, the Chicago White Sox (18–39) will face the Baltimore Orioles (20–36) at Oriole Park at Camden Yards. Both teams are looking to gain momentum as they approach the midseason mark. Chicago White Sox vs Baltimore AI Prediction: Free MLB Betting Insights for Jun 01. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Baltimore Orioles MLB Preview

The Baltimore Orioles return to Oriole Park at Camden Yards on June 1, 2025, to face the Chicago White Sox in a matchup that, while not headlining the MLB slate, offers a valuable opportunity for a young Orioles squad to build momentum heading into the heart of the season. Entering the game with a 20–36 record, Baltimore remains mired near the bottom of the AL East standings, yet recent performances have shown flashes of growth, especially at home, where they’ve historically dominated the White Sox. The Orioles have won four of their last five series against Chicago at Camden Yards, and notably, the last five home games between these teams have gone over the total, suggesting that Baltimore often finds offensive rhythm in this matchup. Ryan O’Hearn has emerged as one of the Orioles’ most dependable bats in recent weeks, providing timely hitting and helping to stabilize a lineup that has been inconsistent throughout the season. Though they’ve posted a 5–5 record against the spread over their last 10 games, their offensive production has gradually improved, and they’ve begun to compete more effectively in close contests. Defensively, Baltimore has room to grow—mental lapses and fielding errors have cost them in tight situations—but the core talent remains promising, and manager Brandon Hyde has leaned on youth while trying to balance patience with accountability.

Their pitching staff, while far from elite, has had moments of competence, though it remains one of the team’s primary weaknesses, with starting depth and bullpen fatigue often putting extra pressure on the offense to carry the load. In this game, Baltimore will look for its starter to provide a quality outing, ideally pitching into the sixth inning to keep strain off a bullpen that has logged a heavy workload over the past week. Offensively, the key will be jumping on Adrian Houser early and forcing the White Sox to play from behind—something they’ve struggled to do effectively this year. If the Orioles can establish a lead by the middle innings, their bullpen is capable of holding serve when not overtaxed, particularly if they can avoid the kind of high-pitch-count innings that have plagued them in previous losses. Playing at home, with favorable historical trends against Chicago and modest betting market support as -169 moneyline favorites, Baltimore is in a position to assert control and string together back-to-back quality performances. Hyde will likely rely on small ball fundamentals and lineup flexibility to keep pressure on a White Sox defense that, despite recent improvement, still ranks near the bottom of the league in most advanced metrics. A win here wouldn’t just help improve Baltimore’s position in the standings—it would provide a much-needed confidence boost for a rebuilding roster that continues to look for consistency and identity. For the Orioles, this matchup represents a prime opportunity to turn home-field comfort into tangible results and begin crafting some momentum for what has otherwise been a frustrating first half.

Chicago White Sox vs. Baltimore Prop Picks (AI)

AI algorithm Remi is pouring through mountains of stats on each line. In fact, anytime the White Sox and Orioles play there’s always several intriguing trends to key in on. Not to mention games played at Oriole Park at Camden Yards in Jun can often follow normal, predictable patterns.
Remi's searched hard and found the best prop for this matchup: A. Benintendi over 0.5 Total Bases.

Chicago White Sox vs. Baltimore Prediction (AI)

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Remi, our AI sports genius, has been pouring over exorbitant amounts of data from every angle between the White Sox and Orioles and using recursive machine learning and industry leading AI to crunch the data to a single cover probability.

Oddly enough, we’ve seen the AI has been most watching on the growing factor human bettors regularly put on Baltimore’s strength factors between a White Sox team going up against a possibly tired Orioles team. We’ve found the true game analytics might reflect a moderate lean against one Vegas line specifically.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI Chicago White Sox vs Baltimore picks, computer picks White Sox vs Orioles, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
MLB 9/26 DET@BOS UNLOCK THIS PICK 5 EXECUTIVE Locked EXECUTIVE
MLB 9/26 BAL@NYY UNLOCK THIS PICK 4 INTEL Locked INTEL
MLB 9/26 ARI@SD UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
MLB 9/26 NYM@MIA UNLOCK THIS PICK 1 INTEL Locked INTEL
MLB 9/26 NYM@MIA GET FREE PICK NOW 1
MLB 9/26 COL@SF UNLOCK THIS PICK 0 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

White Sox Betting Trends

The White Sox have covered the run line in 4 of their last 5 games, showing a profit of 2.52 units.

Orioles Betting Trends

The Orioles have a 5–5 record against the spread over their past 10 games, reflecting inconsistent performance in covering the run line at home.

White Sox vs. Orioles Matchup Trends

The Orioles have won 4 of their last 5 series at Camden Yards against the White Sox, and the last 5 home games between these teams have gone over the total.

Chicago White Sox vs. Baltimore Game Info

Chicago White Sox vs Baltimore starts on June 01, 2025 at 1:35 PM EST.

Venue: Oriole Park at Camden Yards.

Spread: Baltimore -1.5
Moneyline: Chicago White Sox +142, Baltimore -170
Over/Under: 9

Chicago White Sox: (18-40  |  Baltimore: (21-36)

Remi's searched hard and found the best prop for this matchup: A. Benintendi over 0.5 Total Bases.. Prices move—always shop for the best number.

The Orioles have won 4 of their last 5 series at Camden Yards against the White Sox, and the last 5 home games between these teams have gone over the total.

CHW trend: The White Sox have covered the run line in 4 of their last 5 games, showing a profit of 2.52 units.

BAL trend: The Orioles have a 5–5 record against the spread over their past 10 games, reflecting inconsistent performance in covering the run line at home.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

Chicago White Sox vs. Baltimore Odds

AI algorithm Remi is pouring through mountains of data points on each team. In fact, anytime the Chicago White Sox vs Baltimore trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme altitude almost always follow normal, predictable betting trends.

Chicago White Sox vs Baltimore Opening Odds

CHW Moneyline: +142
BAL Moneyline: -170
CHW Spread: +1.5
BAL Spread: -1.5
Over/Under: 9

Chicago White Sox vs Baltimore Live Odds

Games PTS ML SPR O/U
Sep 27, 2025 1:06PM EDT
Baltimore Orioles
New York Yankees
9/27/25 1:06PM
Orioles
Yankees
+194
-235
+1.5 (-105)
-1.5 (-114)
O 8.5 (-122)
U 8.5 (+100)
Sep 27, 2025 2:21PM EDT
St Louis Cardinals
Chicago Cubs
9/27/25 2:21PM
Cardinals
Cubs
 
-168
 
-1.5 (+118)
O 9 (-122)
U 9 (+100)
Sep 27, 2025 3:09PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/27/25 3:09PM
Rays
Blue Jays
+132
-156
+1.5 (-154)
-1.5 (+128)
O 8.5 (-106)
U 8.5 (-114)
Sep 27, 2025 4:06PM EDT
Chicago White Sox
Washington Nationals
9/27/25 4:06PM
White Sox
Nationals
+102
-120
-1.5 (+162)
+1.5 (-196)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 4:06PM EDT
Colorado Rockies
San Francisco Giants
9/27/25 4:06PM
Rockies
Giants
+198
-240
+1.5 (-110)
-1.5 (-110)
O 8 (-108)
U 8 (-112)
Sep 27, 2025 4:11PM EDT
New York Mets
Miami Marlins
9/27/25 4:11PM
Mets
Marlins
-124
+106
-1.5 (+130)
+1.5 (-156)
O 8.5 (-112)
U 8.5 (-108)
Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
+172
-205
+1.5 (-118)
-1.5 (+100)
O 8.5 (-115)
U 8.5 (-105)
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
+128
-152
+1.5 (-178)
-1.5 (+146)
O 7.5 (-120)
U 7.5 (-102)
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
+136
-162
+1.5 (-150)
-1.5 (+125)
O 8 (-105)
U 8 (-115)
Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
+138
-164
+1.5 (-164)
-1.5 (+136)
O 7.5 (-110)
U 7.5 (-110)
Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
+120
-142
+1.5 (-182)
-1.5 (+150)
O 7.5 (-118)
U 7.5 (-104)
Sep 27, 2025 9:39PM EDT
Houston Astros
Los Angeles Angels
9/27/25 9:39PM
Astros
Angels
-162
+136
-1.5 (+100)
+1.5 (-120)
O 9 (+100)
U 9 (-122)
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
+102
-120
+1.5 (-215)
-1.5 (+180)
O 7.5 (-110)
U 7.5 (-110)
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
+100
-118
-1.5 (+152)
+1.5 (-184)
O 10 (-110)
U 10 (-110)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Chicago White Sox White Sox vs. Baltimore Orioles on June 01, 2025 at Oriole Park at Camden Yards.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS
CIN@ARI KEBRYAN HAYES STRIKEOUTS UNDER 0.5 56.2% 6 WIN
LAD@SD SD +110 50.9% 6 WIN