Missouri vs Vanderbilt Prediction — AI Finds CAN'T MISS CFB Lines & Props (Oct 25)

Updated: 2025-10-18T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Missouri Tigers and the Vanderbilt Commodores, both sitting at 6-1 overall and 2-1 in the SEC, meet Saturday in a marquee showdown as Vanderbilt hosts in Nashville. With major playoff implications and national attention via College GameDay, both teams are riding momentum and eager to assert themselves in the conference hierarchy.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Oct 25, 2025

Start Time: 3:30 PM EST​

Venue: FirstBank Stadium​

Commodores Record: (6-1)

Tigers Record: (6-1)

OPENING ODDS

MIZZOU Moneyline: +138

VANDY Moneyline: -164

MIZZOU Spread: +3

VANDY Spread: -3.0

Over/Under: 52.5

MIZZOU
Betting Trends

  • Vanderbilt has covered the spread in approximately 66.7% of games this season (4–2 ATS) and shows a strong underdog/road-covering profile, including an undefeated (6–0) ATS record when a road underdog since 2024.

VANDY
Betting Trends

  • Missouri is covering at around 60.0% of its games ATS this season (3–2-1 ATS) and has been slightly better at home in recent outings, though still just hovering near a 60% cover rate overall.

MATCHUP TRENDS

  • Notably, Vanderbilt’s strong performance as a road underdog and Missouri’s moderate ATS success create an interesting dynamic: the Commodores are trending better ATS in similar situations, and this matchup sees Missouri as the road team yet also as a ranked opponent in a hostile environment. Additionally, games in October at Vanderbilt’s FirstBank Stadium have bucked normal patterns and might favor tight spreads and defensive slants.

MIZZOU vs. VANDY
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup:

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Missouri vs Vanderbilt Prediction & Odds:
Free CFB Betting Insights for 10/25/25

This matchup pits two teams with identical 6-1 records and 2-1 in SEC play into direct competition — both have aspirations beyond just another conference win, and each sees this as a potential pivot point for their season. Missouri arrives having weathered a tight double-overtime win on the road, while Vanderbilt is riding high after a signature victory at home, giving this game major momentum implications for both sides. The Tigers bring physicality and experience in close games under coach Eli Drinkwitz, while the Commodores under Clark Lea have crafted a more balanced identity at home with improving defense and a dual-threat quarterback in Diego Pavia. Missouri will look to impose its will up front, leveraging a defense that has shown the ability to make critical stops in tight spots, but questions remain about whether the Tigers can consistently generate explosive plays and avoid self-inflicted errors when facing a disciplined Vanderbilt unit on its home turf.

Meanwhile, Vanderbilt’s offense has gained confidence converting drives, controlling possession, and using Pavia’s mobility to keep things unpredictable; its defense has improved in the red-zone and on third-down stops, meaning they may be able to slow Missouri’s rhythm and force a rugged, low-scoring battle. The environment in Nashville matters — with increased national attention (including a purpose-built spotlight game) and a raucous home crowd, the Commodores have a built-in edge, but the Tigers are battle tested and accustomed to pressure moments. Ultimately, factors such as turnover margin, special-teams execution, and situational toughness (third-down, red-zone, overtime preparedness) will likely determine which team not only wins but covers the spread. If Missouri can establish the run, protect the football, and stay within itself, they’re dangerous; if Vanderbilt controls tempo, stays disciplined, and maximizes its home-field boost, they could dictate the game’s flow. Expect a close, strategically contested game that may hinge on a few high-leverage plays rather than a runaway score — with both teams’ playoff hopes and conference positioning on the line.

Missouri Tigers CFB Preview

The Missouri Tigers head into their October 25 matchup against Vanderbilt with a mix of confidence and caution, aware that a 6-1 record and a national ranking mean little if they stumble on the road in SEC play. This team has shown grit in tight contests, particularly in its recent double-overtime victory over Auburn, where defense and resilience compensated for offensive inconsistency. Under head coach Eli Drinkwitz, Missouri has developed a tough-minded identity built around balance and control, though the offensive unit still battles inconsistency when it comes to sustaining drives and avoiding turnovers. The Tigers’ success has often come from their ability to pressure opposing quarterbacks and create mistakes, a trend they’ll need to replicate against Vanderbilt’s dual-threat leader Diego Pavia. Missouri’s defensive front is physical, led by an experienced group that excels at clogging running lanes and forcing opponents into long third downs, but Vanderbilt’s quick-pass and option looks will test their discipline and edge containment. Offensively, Missouri leans on quarterback Brady Cook’s decision-making and the playmaking of wideout Luther Burden III, one of the SEC’s most dynamic receivers who can stretch the field and alter defensive schemes. However, protection has been a recurring issue against blitz-heavy defenses, and Vanderbilt’s aggressive pass rush could disrupt the Tigers’ rhythm early.

On the ground, Missouri will try to reestablish its run game behind Cody Schrader, who has shown flashes of dominance but hasn’t consistently found space against top-tier defensive fronts. Drinkwitz’s offensive game plan typically relies on scripted success early and then adjusts to exploit weaknesses, so the Tigers must avoid stalling in early possessions if they want to control tempo. Missouri’s road form in the SEC has been mixed over the past two seasons, marked by strong defensive showings but occasional offensive stagnation in key moments. Vanderbilt’s crowd won’t rival the chaos of larger SEC venues, but with College GameDay in Nashville, this will still be a high-energy environment that could impact communication and timing. The Tigers’ special teams might play an underrated role, especially in a game projected to be close, with kicker Harrison Mevis’ range giving Missouri an edge in late-game field position. Statistically, Missouri’s defense has held opponents to under 20 points in four of seven games, while the offense averages around 32 points per contest — but turnovers have directly impacted two of their tighter results. The Tigers’ task will be to stay ahead of the chains, limit mental mistakes, and force Vanderbilt into quick three-and-outs to dictate field position. Missouri cannot afford to get drawn into a grind-it-out contest on Vanderbilt’s terms, as the Commodores’ time-of-possession edge could wear down even an elite defense. If the Tigers find rhythm through balanced play-calling, protect Cook in the pocket, and capitalize on their speed in open space, they’ll be poised to take control and keep their SEC title hopes alive. But if they repeat the inconsistency and conservative stretches that have occasionally plagued them this season, Vanderbilt’s methodical style could seize control late, leaving Missouri once again vulnerable to a road upset that would redefine its postseason trajectory.

The Missouri Tigers and the Vanderbilt Commodores, both sitting at 6-1 overall and 2-1 in the SEC, meet Saturday in a marquee showdown as Vanderbilt hosts in Nashville. With major playoff implications and national attention via College GameDay, both teams are riding momentum and eager to assert themselves in the conference hierarchy. Missouri vs Vanderbilt AI Prediction: Free CFB Betting Insights for Oct 25. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Vanderbilt Commodores CFB Preview

The Vanderbilt Commodores enter their October 25 home matchup against the Missouri Tigers with confidence and conviction, sitting at 6-1 overall and 2-1 in the SEC, a mark that reflects one of their most complete starts in recent memory. Under head coach Clark Lea, Vanderbilt has steadily evolved from a rebuilding program into a legitimate SEC contender, blending disciplined execution with a balanced offense and a defense that thrives in situational football. Quarterback Diego Pavia has been the centerpiece of this resurgence, using his dual-threat ability to extend plays and frustrate defenses, while running back Patrick Smith provides consistency and toughness between the tackles. Vanderbilt’s offensive approach is built on balance and control — long drives, efficient passing, and an emphasis on winning time of possession — a formula that has helped them outlast more athletic opponents and protect their defense from overexposure. Against Missouri, that philosophy will be put to the test. The Tigers bring one of the SEC’s more opportunistic defenses, capable of creating turnovers and pressuring quarterbacks with disguised fronts, so Vanderbilt’s offensive line play and Pavia’s decision-making will be critical to maintaining rhythm. Wideouts like Jayden McGowan and Will Sheppard add explosive potential, and if Vanderbilt can get them in space against Missouri’s secondary, it could tilt the field in their favor.

Defensively, Vanderbilt’s improvement has been one of the season’s biggest surprises. The Commodores have tightened their red-zone defense significantly, ranking near the top half of the SEC in opponent scoring efficiency inside the 20. Their ability to hold firm on third downs has also been key, forcing offenses into uncomfortable passing situations where Vanderbilt’s pass rush — led by linemen such as Nate Clifton and linebacker Langston Patterson — can make an impact. The Commodores will need to stay fundamentally sound, as Missouri’s offense has the kind of versatility that can exploit overaggression, especially with the downfield threat of Luther Burden III. On special teams, kicker Jacob Ayers has been steady, and Vanderbilt’s return game has generated valuable field position, something that could loom large in a game expected to be tightly contested. Beyond the on-field matchups, Vanderbilt enjoys the intangible edge of playing at home in what’s shaping up to be one of the program’s most anticipated games in years, particularly with national attention from College GameDay descending upon Nashville. The energy at FirstBank Stadium will be unlike any typical Vanderbilt atmosphere, giving this team a legitimate home-field advantage it hasn’t always enjoyed. Historically, the Commodores have struggled to close out big games, but this year’s squad has shown maturity and late-game poise, turning close contests into statement wins, including their recent triumph over LSU. To beat Missouri, Vanderbilt must stick to its formula: control the clock, limit turnovers, win special-teams moments, and force the Tigers into uncomfortable offensive positions. If they can execute with the same precision and confidence they’ve displayed in recent weeks, Vanderbilt won’t just challenge Missouri — they’ll have a genuine opportunity to solidify themselves as one of the SEC’s most compelling success stories of 2025.

Missouri vs. Vanderbilt Prop Picks (AI)

AI algorithm Remi is pouring through tons of data on each team. In fact, anytime the Tigers and Commodores play there’s always several intriguing trends to key in on. Not to mention games played at FirstBank Stadium in Oct almost always follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup:

Missouri vs. Vanderbilt Prediction (AI)

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Remi, our AI sports genius, has been pouring over tons of data from every simulation between the Tigers and Commodores and using recursive machine learning and impressive AI to analyze the data to a single cover probability.

Remi has been most watching on the trending factor human bettors tend to put on Vanderbilt’s strength factors between a Tigers team going up against a possibly healthy Commodores team. It appears the true game analytics might reflect a moderate lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our CFB AI picks for FREE now.

Below is our current AI Missouri vs Vanderbilt picks, computer picks Tigers vs Commodores, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
CFB 10/21 KENSAW@FIU UNLOCK THIS PICK 3 EXECUTIVE Locked EXECUTIVE
CFB 10/21 WKY@LATECH UNLOCK THIS PICK 2 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full CFB schedule

Tigers Betting Trends

Vanderbilt has covered the spread in approximately 66.7% of games this season (4–2 ATS) and shows a strong underdog/road-covering profile, including an undefeated (6–0) ATS record when a road underdog since 2024.

Commodores Betting Trends

Missouri is covering at around 60.0% of its games ATS this season (3–2-1 ATS) and has been slightly better at home in recent outings, though still just hovering near a 60% cover rate overall.

Tigers vs. Commodores Matchup Trends

Notably, Vanderbilt’s strong performance as a road underdog and Missouri’s moderate ATS success create an interesting dynamic: the Commodores are trending better ATS in similar situations, and this matchup sees Missouri as the road team yet also as a ranked opponent in a hostile environment. Additionally, games in October at Vanderbilt’s FirstBank Stadium have bucked normal patterns and might favor tight spreads and defensive slants.

Missouri vs. Vanderbilt Game Info

Missouri vs Vanderbilt starts on October 25, 2025 at 3:30 PM EST.

Spread: Vanderbilt -3.0
Moneyline: Missouri +138, Vanderbilt -164
Over/Under: 52.5

Missouri: (6-1)  |  Vanderbilt: (6-1)

Remi's searched hard and found the best prop for this matchup:. Prices move—always shop for the best number.

Notably, Vanderbilt’s strong performance as a road underdog and Missouri’s moderate ATS success create an interesting dynamic: the Commodores are trending better ATS in similar situations, and this matchup sees Missouri as the road team yet also as a ranked opponent in a hostile environment. Additionally, games in October at Vanderbilt’s FirstBank Stadium have bucked normal patterns and might favor tight spreads and defensive slants.

MIZZOU trend: Vanderbilt has covered the spread in approximately 66.7% of games this season (4–2 ATS) and shows a strong underdog/road-covering profile, including an undefeated (6–0) ATS record when a road underdog since 2024.

VANDY trend: Missouri is covering at around 60.0% of its games ATS this season (3–2-1 ATS) and has been slightly better at home in recent outings, though still just hovering near a 60% cover rate overall.

See our latest CFB picks and odds pages for 2025 to compare prices before you bet.

Missouri vs. Vanderbilt Odds

Remi is pouring through tons of stats on each line. In fact, anytime the Missouri vs Vanderbilt trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme travel distance seemingly never follow normal, predictable betting trends.

Missouri vs Vanderbilt Opening Odds

MIZZOU Moneyline: +138
VANDY Moneyline: -164
MIZZOU Spread: +3
VANDY Spread: -3.0
Over/Under: 52.5

Missouri vs Vanderbilt Live Odds

Games PTS ML SPR O/U
Oct 22, 2025 7:30PM EDT
MTSU Blue Raiders
Delaware Blue Hens
10/22/25 7:30PM
MTSU
DEL
 
-360
 
-9.5 (-110)
O 55 (-110)
U 55 (-110)
Oct 22, 2025 9:00PM EDT
Missouri State Bears
New Mexico State Aggies
10/22/25 9PM
MIZZST
NMEXST
-110
-110
-1 (-105)
+1 (-115)
O 50.5 (-110)
U 50.5 (-110)
Oct 23, 2025 7:30PM EDT
South Alabama Jaguars
Georgia State Panthers
10/23/25 7:30PM
SBAMA
GAST
-230
+190
-6.5 (-110)
+6.5 (-110)
O 56 (-110)
U 56 (-110)
Oct 24, 2025 7:00PM EDT
North Texas Mean Green
Charlotte 49ers
10/24/25 7PM
NOTEX
CHARLO
-5000
+1300
-27 (+100)
+27 (-120)
O 61.5 (-110)
U 61.5 (-110)
Oct 24, 2025 7:30PM EDT
California Golden Bears
Virginia Tech Hokies
10/24/25 7:30PM
CAL
VATECH
+170
-200
+4.5 (-110)
-4.5 (-110)
O 50 (-110)
U 50 (-110)
Oct 24, 2025 10:00PM EDT
Boise State Broncos
Nevada Wolf Pack
10/24/25 10PM
BOISE
NEVADA
-1800
+850
-21 (-110)
+21 (-110)
O 50.5 (-105)
U 50.5 (-115)
Oct 25, 2025 12:00PM EDT
Virginia Cavaliers
North Carolina Tar Heels
10/25/25 12PM
UVA
UNC
-410
+305
-10.5 (-105)
+10.5 (-115)
O 52 (-105)
U 52 (-115)
Oct 25, 2025 12:00PM EDT
Bowling Green Falcons
Kent State Golden Flashes
10/25/25 12PM
BGREEN
KENT
-290
+240
-7 (-115)
+7 (-105)
O 48.5 (-110)
U 48.5 (-110)
Oct 25, 2025 12:00PM EDT
Rutgers Scarlet Knights
Purdue Boilermakers
10/25/25 12PM
RUT
PURDUE
-130
+110
-2.5 (-115)
+2.5 (-105)
O 58.5 (-110)
U 58.5 (-110)
Oct 25, 2025 12:00PM EDT
South Florida Bulls
Memphis Tigers
10/25/25 12PM
SFLA
MEMP
-200
+170
-4.5 (-110)
+4.5 (-110)
O 63.5 (-110)
U 63.5 (-110)
Oct 25, 2025 12:00PM EDT
UCLA Bruins
Indiana Hoosiers
10/25/25 12PM
UCLA
IND
+1100
-3500
+25.5 (-110)
-25.5 (-110)
O 55.5 (-110)
U 55.5 (-110)
Oct 25, 2025 12:00PM EDT
Northwestern Wildcats
Nebraska Cornhuskers
10/25/25 12PM
NWEST
NEB
+235
-285
+7 (-105)
-7 (-115)
O 43.5 (-110)
U 43.5 (-110)
Oct 25, 2025 12:00PM EDT
Ohio Bobcats
Eastern Michigan Eagles
10/25/25 12PM
OHIO
EMICH
-480
+350
-12.5 (-110)
+12.5 (-110)
O 59.5 (-115)
U 59.5 (-105)
Oct 25, 2025 12:00PM EDT
SMU Mustangs
Wake Forest Demon Deacons
10/25/25 12PM
SMU
WAKE
-175
+150
-3.5 (-105)
+3.5 (-115)
O 54 (-110)
U 54 (-110)
Oct 25, 2025 12:00PM EDT
Syracuse Orange
Georgia Tech Yellow Jackets
10/25/25 12PM
CUSE
GATECH
+600
-950
+17.5 (-110)
-17.5 (-110)
O 53.5 (-105)
U 53.5 (-115)
Oct 25, 2025 12:00PM EDT
App State Mountaineers
Old Dominion Monarchs
10/25/25 12PM
APPST
OLDDOM
 
-625
 
-14.5 (-105)
O 63 (-110)
U 63 (-110)
Oct 25, 2025 12:00PM EDT
Ole Miss Rebels
Oklahoma Sooners
10/25/25 12PM
OLEMISS
OKLA
+175
-210
+5 (-110)
-5 (-110)
O 54.5 (-110)
U 54.5 (-110)
Oct 25, 2025 12:00PM EDT
Kansas State Wildcats
Kansas Jayhawks
10/25/25 12PM
KSTATE
KANSAS
+130
-150
+3 (-110)
-3 (-110)
O 56.5 (-110)
U 56.5 (-110)
Oct 25, 2025 12:45PM EDT
Auburn Tigers
Arkansas Razorbacks
10/25/25 12:45PM
AUBURN
ARK
-105
-115
+1 (-110)
-1 (-110)
O 57 (-105)
U 57 (-115)
Oct 25, 2025 1:00PM EDT
Akron Zips
Buffalo Bulls
10/25/25 1PM
AKRON
BUFF
+285
-370
+9.5 (-110)
-9.5 (-110)
O 47 (-110)
U 47 (-110)
Oct 25, 2025 3:00PM EDT
UConn Huskies
Rice Owls
10/25/25 3PM
UCONN
RICE
-420
+315
-11 (-105)
+11 (-115)
O 49 (-110)
U 49 (-110)
Oct 25, 2025 3:00PM EDT
Utah State Aggies
New Mexico Lobos
10/25/25 3PM
UTAHST
NMEX
+130
-150
+3 (-110)
-3 (-110)
O 61.5 (-110)
U 61.5 (-110)
Oct 25, 2025 3:30PM EDT
Minnesota Golden Gophers
Iowa Hawkeyes
10/25/25 3:30PM
MINN
IOWA
+270
-340
+9.5 (-110)
-9.5 (-110)
O 39 (-110)
U 39 (-110)
Oct 25, 2025 3:30PM EDT
Alabama Crimson Tide
South Carolina Gamecocks
10/25/25 3:30PM
BAMA
SC
-510
+370
-12.5 (-110)
+12.5 (-110)
O 47.5 (-110)
U 47.5 (-110)
Oct 25, 2025 3:30PM EDT
BYU Cougars
Iowa State Cyclones
10/25/25 3:30PM
BYU
IOWAST
+120
-140
+2.5 (+105)
-2.5 (-125)
O 48.5 (-110)
U 48.5 (-110)
Oct 25, 2025 3:30PM EDT
Temple Owls
Tulsa Golden Hurricane
10/25/25 3:30PM
TEMPLE
TULSA
-225
+185
-6 (-110)
+6 (-110)
O 53.5 (-110)
U 53.5 (-110)
Oct 25, 2025 3:30PM EDT
Ball State Cardinals
Northern Illinois Huskies
10/25/25 3:30PM
BALLST
NILL
+180
-220
+5.5 (-110)
-5.5 (-110)
O 41 (-115)
U 41 (-105)
Oct 25, 2025 3:30PM EDT
Toledo Rockets
Washington State Cougars
10/25/25 3:30PM
TOLEDO
WASHST
-105
-115
+1 (-110)
-1 (-110)
O 46.5 (-110)
U 46.5 (-110)
Oct 25, 2025 3:30PM EDT
Florida Atlantic Owls
Navy Midshipmen
10/25/25 3:30PM
FAU
NAVY
+460
-675
+15 (-110)
-15 (-110)
O 62.5 (-110)
U 62.5 (-110)
Oct 25, 2025 3:30PM EDT
Illinois Fighting Illini
Washington Huskies
10/25/25 3:30PM
ILL
WASH
+165
-195
+4.5 (-110)
-4.5 (-110)
O 54 (-105)
U 54 (-115)
Oct 25, 2025 3:30PM EDT
Umass Minutemen
Central Michigan Chippewas
10/25/25 3:30PM
UMASS
CMICH
 
-750
 
-16 (-110)
O 47 (-110)
U 47 (-110)
Oct 25, 2025 3:30PM EDT
San Diego State Aztecs
Fresno State Bulldogs
10/25/25 3:30PM
SDGST
FRESNO
-150
+130
-3 (-110)
+3 (-110)
O 48 (-110)
U 48 (-110)
Oct 25, 2025 3:30PM EDT
Missouri Tigers
Vanderbilt Commodores
10/25/25 3:30PM
MIZZOU
VANDY
+115
-135
+2.5 (-105)
-2.5 (-115)
O 52 (-110)
U 52 (-110)
Oct 25, 2025 3:30PM EDT
NC State Wolfpack
Pittsburgh Panthers
10/25/25 3:30PM
NCST
PITT
+210
-250
+6.5 (-110)
-6.5 (-110)
O 57 (-110)
U 57 (-110)
Oct 25, 2025 3:30PM EDT
Western Michigan Broncos
Miami Ohio Redhawks
10/25/25 3:30PM
WMICH
MIAOH
+100
 
+1.5 (-115)
 
O 41 (-115)
U 41 (-105)
Oct 25, 2025 3:30PM EDT
UL Monroe Warhawks
USM Golden Eagles
10/25/25 3:30PM
MONROE
USM
+335
 
+11 (-110)
 
O 50.5 (-110)
U 50.5 (-110)
Oct 25, 2025 4:00PM EDT
Oklahoma State Cowboys
Texas Tech Red Raiders
10/25/25 4PM
OKLAST
TXTECH
+3000
-10000
+38.5 (-115)
-38.5 (-105)
O 56.5 (-110)
U 56.5 (-110)
Oct 25, 2025 4:00PM EDT
Baylor Bears
Cincinnati Bearcats
10/25/25 4PM
BAYLOR
CINCY
+160
-185
+4 (-110)
-4 (-110)
O 67 (-110)
U 67 (-110)
Oct 25, 2025 4:15PM EDT
Texas Longhorns
Mississippi State Bulldogs
10/25/25 4:15PM
TEXAS
MISSST
-260
+215
-7 (-105)
+7 (-115)
O 45 (-110)
U 45 (-110)
Oct 25, 2025 6:00PM EDT
TCU Horned Frogs
West Virginia Mountaineers
10/25/25 6PM
TCU
WVU
-675
+460
-15 (-110)
+15 (-110)
O 55 (-105)
U 55 (-115)
Oct 25, 2025 7:00PM EDT
Wisconsin Badgers
Oregon Ducks
10/25/25 7PM
WISC
OREG
 
 
+33.5 (-110)
-33.5 (-110)
O 44.5 (-110)
U 44.5 (-110)
Oct 25, 2025 7:00PM EDT
Louisiana Ragin Cajuns
Troy Trojans
10/25/25 7PM
UL
TROY
+260
-320
+8 (-110)
-8 (-110)
O 47.5 (-110)
U 47.5 (-110)
Oct 25, 2025 7:00PM EDT
Stanford Cardinal
Miami Hurricanes
10/25/25 7PM
STNFRD
MIAMI
+4000
-30000
+30 (-115)
-30 (-105)
O 45.5 (-110)
U 45.5 (-110)
Oct 25, 2025 7:00PM EDT
Georgia Southern Eagles
Arkansas State Red Wolves
10/25/25 7PM
GASO
ARKST
+100
-120
+1.5 (-110)
-1.5 (-110)
O 63.5 (-110)
U 63.5 (-110)
Oct 25, 2025 7:30PM EDT
Michigan Wolverines
Michigan State Spartans
10/25/25 7:30PM
MICH
MICHST
-625
+430
-14.5 (-105)
+14.5 (-115)
O 47.5 (-110)
U 47.5 (-110)
Oct 25, 2025 7:30PM EDT
Texas A&M Aggies
LSU Tigers
10/25/25 7:30PM
TEXAM
LSU
-135
+115
-2.5 (-115)
+2.5 (-105)
O 48 (-105)
U 48 (-115)
Oct 25, 2025 7:30PM EDT
Boston College Eagles
Louisville Cardinals
10/25/25 7:30PM
BC
LVILLE
+1100
-3300
+25 (-110)
-25 (-110)
O 55.5 (-105)
U 55.5 (-115)
Oct 25, 2025 7:30PM EDT
Colorado State Rams
Wyoming Cowboys
10/25/25 7:30PM
COLOST
WYO
+180
-220
+5.5 (-105)
-5.5 (-115)
O 46.5 (-110)
U 46.5 (-110)
Oct 25, 2025 7:45PM EDT
Tennessee Volunteers
Kentucky Wildcats
10/25/25 7:45PM
TENN
UK
-350
+275
-9.5 (-110)
+9.5 (-110)
O 54 (-115)
U 54 (-105)
Oct 25, 2025 8:00PM EDT
Houston Cougars
Arizona State Sun Devils
10/25/25 8PM
HOU
ARIZST
+250
-300
+7.5 (-115)
-7.5 (-105)
O 47 (-110)
U 47 (-110)
Oct 25, 2025 10:15PM EDT
Colorado Buffaloes
Utah Utes
10/25/25 10:15PM
COLO
UTAH
+425
-600
+14 (-115)
-14 (-105)
O 50 (-110)
U 50 (-110)
Oct 28, 2025 8:00PM EDT
James Madison Dukes
Texas State Bobcats
10/28/25 8PM
JMAD
TEXST
-275
+220
-7.5 (-104)
+7.5 (-118)
O 60.5 (-112)
U 60.5 (-108)
Oct 30, 2025 7:30PM EDT
Tulane Green Wave
UTSA Roadrunners
10/30/25 7:30PM
TULANE
UTSA
-200
+164
-5.5 (-110)
+5.5 (-110)
O 52.5 (-112)
U 52.5 (-108)
Nov 1, 2025 12:00PM EDT
Penn State Nittany Lions
Ohio State Buckeyes
11/1/25 12PM
PSU
OHIOST
+660
-1050
+17.5 (-115)
-17.5 (-105)
O 47.5 (-110)
U 47.5 (-110)
Nov 1, 2025 12:00PM EDT
Miami Hurricanes
SMU Mustangs
11/1/25 12PM
MIAMI
SMU
-430
+330
-10.5 (-110)
+10.5 (-110)
O 51.5 (-110)
U 51.5 (-110)
Nov 1, 2025 12:00PM EDT
Oklahoma Sooners
Tennessee Volunteers
11/1/25 12PM
OKLA
TENN
-105
-114
+1.5 (-114)
-1.5 (-106)
O 53.5 (-112)
U 53.5 (-108)
Nov 1, 2025 12:00PM EDT
Vanderbilt Commodores
Texas Longhorns
11/1/25 12PM
VANDY
TEXAS
+150
-182
+3.5 (-106)
-3.5 (-114)
O 45.5 (-110)
U 45.5 (-110)
Nov 1, 2025 3:30PM EDT
Georgia Bulldogs
Florida Gators
11/1/25 3:30PM
UGA
FLA
-300
+240
-7.5 (-110)
+7.5 (-110)
O 50.5 (-112)
U 50.5 (-108)

CFB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Missouri Tigers vs. Vanderbilt Commodores on October 25, 2025 at FirstBank Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our CFB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
FSU@STNFRD STNFRD +18 56.6% 6 WIN
WASHST@UVA WASHST +17.5 58.8% 8 WIN
NEVADA@NMEX NEVADA +13.5 57.8% 7 WIN
TEXAS@UK ARCH MANNING UNDER 1.5 PASS TD 56.1% 6 WIN
ARMY@TULANE ARMY +10 55.3% 5 WIN
SJST@UTAHST SJST +4 54.4% 4 LOSS
LVILLE@MIAMI LVILLE +12.5 56.5% 6 WIN
LVILLE@MIAMI CJ DANIELS UNDER 4.5 RECEPTIONS 54.4 4 LOSS
DEL@JAXST DEL -2.5 57.6% 6 LOSS
UTEP@SAMST UTEP -2.5 53.9% 3 WIN
FIU@WKY FIU +10.5 54.6% 4 WIN
ARKST@SALA ARKST +7.5 54.5% 4 WIN
ARKST@SALA JAYLEN RAYNOR UNDER 40.5 LONGEST PASS COMP 53.3% 3 WIN
SJST@WYO SJST -120 59.8% 7 LOSS
UMASS@KENTST KENTST -135 60.2% 6 WIN
NOILL@EMICH EMICH +2.5 53.9% 3 WIN
BYU@ARIZ ARIZ +2.5 54.2% 3 LOSS
OKLA@TEXAS OKLA +2.5 54.7% 4 LOSS
NMEX@BOISE NMEX +16.5 56.4% 6 WIN
WAKE@OREGST WAKE -2.5 56.7% 6 WIN
ULMON@COASTAL ULMON -2.5 56.8% 6 LOSS
IOWA@WISC WISC +4 54.8% 4 LOSS
TOLEDO@BGREEN TOLEDO -10 56.3% 6 LOSS
SFLA@NOTEX SFLA +2.5 54.3% 4 WIN
FRESNO@COLOST RICHIE ANDERSON III LONGEST RECEPTION UNDER 16.5 54.4% 4 LOSS
JAXST@SAMST SAMST +7.5 55.3% 5 WIN
USM@GAS GAS +3.5 57.4% 7 WIN
LIB@UTEP UTEP +2 54.5% 4 LOSS
SALA@TROY SALA -118 55.2% 4 LOSS
TULSA@MEMP MEMP -20.5 53.8% 3 WIN
JMAD@GAST GAST +20.5 54.6% 4 WIN
WAKE@VATECH VATECH -5.5 56.6% 6 LOSS
UNLV@WYO WYO +4.5 55.5% 5 LOSS
PSU@UCLA PSU -24.5 56.3% 6 LOSS
TXSTSM@ARKST TXSTSM -13 56.7% 6 LOSS
UVA@LVILLE ISAAC BROWN OVER 70.5 RUSH YDS 56.6% 6 LOSS
WVU@BYU WVU +20.5 54.7% 4 WIN
SAMST@NMEXST SAMST -1.5 54.1% 3 LOSS
EMICH@CMICH CMICH -148 62.8% 7 WIN
SDGST@NOILL SDGST -118 55.7% 3 WIN
BAMA@GEORGIA GEORGIA -125 58.7% 7 LOSS
TENN@MISSST MISSST +7.5 54.3% 4 WIN
UK@SC SC -5.5 54.8% 4 WIN
WKY@MIZZST MIZZST +4.5 55.6% 6 LOSS
JAXST@USM USM -3.5 56.0% 5 WIN
NMEXST@NMEX NMEX -14.5 56.9% 6 WIN
ARIZ@IOWAST ROCCO BECHT UNDER 1.5 PASS TDS 55.5% 5 WIN
TCU@ARIZST JOSH HOOVER PASS YDS UNDER 287.5 53.4% 3 WIN
ARIZST@BAYLOR BAYLOR -130 58.4% 6 LOSS
WYO@COLO WYO +13.5 54.1% 3 LOSS
TULANE@OLEMISS MISS -11.5 54.3% 4 WIN