Missouri vs Vanderbilt Prediction — AI Finds CAN'T MISS CFB Lines & Props (Oct 25)
Updated: 2025-10-18T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The Missouri Tigers and the Vanderbilt Commodores, both sitting at 6-1 overall and 2-1 in the SEC, meet Saturday in a marquee showdown as Vanderbilt hosts in Nashville. With major playoff implications and national attention via College GameDay, both teams are riding momentum and eager to assert themselves in the conference hierarchy.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Oct 25, 2025
Start Time: 3:30 PM EST
Venue: FirstBank Stadium
Commodores Record: (6-1)
Tigers Record: (6-1)
OPENING ODDS
MIZZOU Moneyline: +138
VANDY Moneyline: -164
MIZZOU Spread: +3
VANDY Spread: -3.0
Over/Under: 52.5
MIZZOU
Betting Trends
- Vanderbilt has covered the spread in approximately 66.7% of games this season (4–2 ATS) and shows a strong underdog/road-covering profile, including an undefeated (6–0) ATS record when a road underdog since 2024.
VANDY
Betting Trends
- Missouri is covering at around 60.0% of its games ATS this season (3–2-1 ATS) and has been slightly better at home in recent outings, though still just hovering near a 60% cover rate overall.
MATCHUP TRENDS
- Notably, Vanderbilt’s strong performance as a road underdog and Missouri’s moderate ATS success create an interesting dynamic: the Commodores are trending better ATS in similar situations, and this matchup sees Missouri as the road team yet also as a ranked opponent in a hostile environment. Additionally, games in October at Vanderbilt’s FirstBank Stadium have bucked normal patterns and might favor tight spreads and defensive slants.
MIZZOU vs. VANDY
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup:
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Missouri vs Vanderbilt Prediction & Odds:
Free CFB Betting Insights for 10/25/25
Meanwhile, Vanderbilt’s offense has gained confidence converting drives, controlling possession, and using Pavia’s mobility to keep things unpredictable; its defense has improved in the red-zone and on third-down stops, meaning they may be able to slow Missouri’s rhythm and force a rugged, low-scoring battle. The environment in Nashville matters — with increased national attention (including a purpose-built spotlight game) and a raucous home crowd, the Commodores have a built-in edge, but the Tigers are battle tested and accustomed to pressure moments. Ultimately, factors such as turnover margin, special-teams execution, and situational toughness (third-down, red-zone, overtime preparedness) will likely determine which team not only wins but covers the spread. If Missouri can establish the run, protect the football, and stay within itself, they’re dangerous; if Vanderbilt controls tempo, stays disciplined, and maximizes its home-field boost, they could dictate the game’s flow. Expect a close, strategically contested game that may hinge on a few high-leverage plays rather than a runaway score — with both teams’ playoff hopes and conference positioning on the line.
Cinema. #MIZ | #STP pic.twitter.com/nwW8VuQ6EQ
— Mizzou Football (@MizzouFootball) October 19, 2025
Missouri Tigers CFB Preview
The Missouri Tigers head into their October 25 matchup against Vanderbilt with a mix of confidence and caution, aware that a 6-1 record and a national ranking mean little if they stumble on the road in SEC play. This team has shown grit in tight contests, particularly in its recent double-overtime victory over Auburn, where defense and resilience compensated for offensive inconsistency. Under head coach Eli Drinkwitz, Missouri has developed a tough-minded identity built around balance and control, though the offensive unit still battles inconsistency when it comes to sustaining drives and avoiding turnovers. The Tigers’ success has often come from their ability to pressure opposing quarterbacks and create mistakes, a trend they’ll need to replicate against Vanderbilt’s dual-threat leader Diego Pavia. Missouri’s defensive front is physical, led by an experienced group that excels at clogging running lanes and forcing opponents into long third downs, but Vanderbilt’s quick-pass and option looks will test their discipline and edge containment. Offensively, Missouri leans on quarterback Brady Cook’s decision-making and the playmaking of wideout Luther Burden III, one of the SEC’s most dynamic receivers who can stretch the field and alter defensive schemes. However, protection has been a recurring issue against blitz-heavy defenses, and Vanderbilt’s aggressive pass rush could disrupt the Tigers’ rhythm early.
On the ground, Missouri will try to reestablish its run game behind Cody Schrader, who has shown flashes of dominance but hasn’t consistently found space against top-tier defensive fronts. Drinkwitz’s offensive game plan typically relies on scripted success early and then adjusts to exploit weaknesses, so the Tigers must avoid stalling in early possessions if they want to control tempo. Missouri’s road form in the SEC has been mixed over the past two seasons, marked by strong defensive showings but occasional offensive stagnation in key moments. Vanderbilt’s crowd won’t rival the chaos of larger SEC venues, but with College GameDay in Nashville, this will still be a high-energy environment that could impact communication and timing. The Tigers’ special teams might play an underrated role, especially in a game projected to be close, with kicker Harrison Mevis’ range giving Missouri an edge in late-game field position. Statistically, Missouri’s defense has held opponents to under 20 points in four of seven games, while the offense averages around 32 points per contest — but turnovers have directly impacted two of their tighter results. The Tigers’ task will be to stay ahead of the chains, limit mental mistakes, and force Vanderbilt into quick three-and-outs to dictate field position. Missouri cannot afford to get drawn into a grind-it-out contest on Vanderbilt’s terms, as the Commodores’ time-of-possession edge could wear down even an elite defense. If the Tigers find rhythm through balanced play-calling, protect Cook in the pocket, and capitalize on their speed in open space, they’ll be poised to take control and keep their SEC title hopes alive. But if they repeat the inconsistency and conservative stretches that have occasionally plagued them this season, Vanderbilt’s methodical style could seize control late, leaving Missouri once again vulnerable to a road upset that would redefine its postseason trajectory.

Credit: USA TODAY/IMAGN
Vanderbilt Commodores CFB Preview
The Vanderbilt Commodores enter their October 25 home matchup against the Missouri Tigers with confidence and conviction, sitting at 6-1 overall and 2-1 in the SEC, a mark that reflects one of their most complete starts in recent memory. Under head coach Clark Lea, Vanderbilt has steadily evolved from a rebuilding program into a legitimate SEC contender, blending disciplined execution with a balanced offense and a defense that thrives in situational football. Quarterback Diego Pavia has been the centerpiece of this resurgence, using his dual-threat ability to extend plays and frustrate defenses, while running back Patrick Smith provides consistency and toughness between the tackles. Vanderbilt’s offensive approach is built on balance and control — long drives, efficient passing, and an emphasis on winning time of possession — a formula that has helped them outlast more athletic opponents and protect their defense from overexposure. Against Missouri, that philosophy will be put to the test. The Tigers bring one of the SEC’s more opportunistic defenses, capable of creating turnovers and pressuring quarterbacks with disguised fronts, so Vanderbilt’s offensive line play and Pavia’s decision-making will be critical to maintaining rhythm. Wideouts like Jayden McGowan and Will Sheppard add explosive potential, and if Vanderbilt can get them in space against Missouri’s secondary, it could tilt the field in their favor.
Defensively, Vanderbilt’s improvement has been one of the season’s biggest surprises. The Commodores have tightened their red-zone defense significantly, ranking near the top half of the SEC in opponent scoring efficiency inside the 20. Their ability to hold firm on third downs has also been key, forcing offenses into uncomfortable passing situations where Vanderbilt’s pass rush — led by linemen such as Nate Clifton and linebacker Langston Patterson — can make an impact. The Commodores will need to stay fundamentally sound, as Missouri’s offense has the kind of versatility that can exploit overaggression, especially with the downfield threat of Luther Burden III. On special teams, kicker Jacob Ayers has been steady, and Vanderbilt’s return game has generated valuable field position, something that could loom large in a game expected to be tightly contested. Beyond the on-field matchups, Vanderbilt enjoys the intangible edge of playing at home in what’s shaping up to be one of the program’s most anticipated games in years, particularly with national attention from College GameDay descending upon Nashville. The energy at FirstBank Stadium will be unlike any typical Vanderbilt atmosphere, giving this team a legitimate home-field advantage it hasn’t always enjoyed. Historically, the Commodores have struggled to close out big games, but this year’s squad has shown maturity and late-game poise, turning close contests into statement wins, including their recent triumph over LSU. To beat Missouri, Vanderbilt must stick to its formula: control the clock, limit turnovers, win special-teams moments, and force the Tigers into uncomfortable offensive positions. If they can execute with the same precision and confidence they’ve displayed in recent weeks, Vanderbilt won’t just challenge Missouri — they’ll have a genuine opportunity to solidify themselves as one of the SEC’s most compelling success stories of 2025.
POV: You take the field with the Dores 🎥 pic.twitter.com/Tj9GO5Qr74
— #10 Vanderbilt Football (@VandyFootball) October 20, 2025
Missouri vs. Vanderbilt Prop Picks (AI)
Missouri vs. Vanderbilt Prediction (AI)

Remi, our AI sports genius, has been pouring over tons of data from every simulation between the Tigers and Commodores and using recursive machine learning and impressive AI to analyze the data to a single cover probability.
Remi has been most watching on the trending factor human bettors tend to put on Vanderbilt’s strength factors between a Tigers team going up against a possibly healthy Commodores team. It appears the true game analytics might reflect a moderate lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our CFB AI picks for FREE now.
Below is our current AI Missouri vs Vanderbilt picks, computer picks Tigers vs Commodores, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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CFB | 10/21 | KENSAW@FIU | UNLOCK THIS PICK | 3 |
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CFB | 10/21 | WKY@LATECH | UNLOCK THIS PICK | 2 |
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full CFB schedule.
Tigers Betting Trends
Vanderbilt has covered the spread in approximately 66.7% of games this season (4–2 ATS) and shows a strong underdog/road-covering profile, including an undefeated (6–0) ATS record when a road underdog since 2024.
Commodores Betting Trends
Missouri is covering at around 60.0% of its games ATS this season (3–2-1 ATS) and has been slightly better at home in recent outings, though still just hovering near a 60% cover rate overall.
Tigers vs. Commodores Matchup Trends
Notably, Vanderbilt’s strong performance as a road underdog and Missouri’s moderate ATS success create an interesting dynamic: the Commodores are trending better ATS in similar situations, and this matchup sees Missouri as the road team yet also as a ranked opponent in a hostile environment. Additionally, games in October at Vanderbilt’s FirstBank Stadium have bucked normal patterns and might favor tight spreads and defensive slants.
Missouri vs. Vanderbilt Game Info
What time does Missouri vs Vanderbilt start on October 25, 2025?
Missouri vs Vanderbilt starts on October 25, 2025 at 3:30 PM EST.
Where is Missouri vs Vanderbilt being played?
Venue: FirstBank Stadium.
What are the opening odds for Missouri vs Vanderbilt?
Spread: Vanderbilt -3.0
Moneyline: Missouri +138, Vanderbilt -164
Over/Under: 52.5
What are the records for Missouri vs Vanderbilt?
Missouri: (6-1) | Vanderbilt: (6-1)
What is the AI best bet for Missouri vs Vanderbilt?
Remi's searched hard and found the best prop for this matchup:. Prices move—always shop for the best number.
What are Missouri vs Vanderbilt trending bets?
Notably, Vanderbilt’s strong performance as a road underdog and Missouri’s moderate ATS success create an interesting dynamic: the Commodores are trending better ATS in similar situations, and this matchup sees Missouri as the road team yet also as a ranked opponent in a hostile environment. Additionally, games in October at Vanderbilt’s FirstBank Stadium have bucked normal patterns and might favor tight spreads and defensive slants.
What are Missouri trending bets?
MIZZOU trend: Vanderbilt has covered the spread in approximately 66.7% of games this season (4–2 ATS) and shows a strong underdog/road-covering profile, including an undefeated (6–0) ATS record when a road underdog since 2024.
What are Vanderbilt trending bets?
VANDY trend: Missouri is covering at around 60.0% of its games ATS this season (3–2-1 ATS) and has been slightly better at home in recent outings, though still just hovering near a 60% cover rate overall.
Where can I find AI Picks for Missouri vs Vanderbilt?
See our latest CFB picks and odds pages for 2025 to compare prices before you bet.
Missouri vs. Vanderbilt Odds
Remi is pouring through tons of stats on each line. In fact, anytime the Missouri vs Vanderbilt trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme travel distance seemingly never follow normal, predictable betting trends.
Missouri vs Vanderbilt Opening Odds
MIZZOU Moneyline:
+138 VANDY Moneyline: -164
MIZZOU Spread: +3
VANDY Spread: -3.0
Over/Under: 52.5
Missouri vs Vanderbilt Live Odds
Games | PTS | ML | SPR | O/U | |
---|---|---|---|---|---|
Oct 22, 2025 7:30PM EDT
MTSU Blue Raiders
Delaware Blue Hens
10/22/25 7:30PM
MTSU
DEL
|
–
–
|
-360
|
-9.5 (-110)
|
O 55 (-110)
U 55 (-110)
|
|
Oct 22, 2025 9:00PM EDT
Missouri State Bears
New Mexico State Aggies
10/22/25 9PM
MIZZST
NMEXST
|
–
–
|
-110
-110
|
-1 (-105)
+1 (-115)
|
O 50.5 (-110)
U 50.5 (-110)
|
|
Oct 23, 2025 7:30PM EDT
South Alabama Jaguars
Georgia State Panthers
10/23/25 7:30PM
SBAMA
GAST
|
–
–
|
-230
+190
|
-6.5 (-110)
+6.5 (-110)
|
O 56 (-110)
U 56 (-110)
|
|
Oct 24, 2025 7:00PM EDT
North Texas Mean Green
Charlotte 49ers
10/24/25 7PM
NOTEX
CHARLO
|
–
–
|
-5000
+1300
|
-27 (+100)
+27 (-120)
|
O 61.5 (-110)
U 61.5 (-110)
|
|
Oct 24, 2025 7:30PM EDT
California Golden Bears
Virginia Tech Hokies
10/24/25 7:30PM
CAL
VATECH
|
–
–
|
+170
-200
|
+4.5 (-110)
-4.5 (-110)
|
O 50 (-110)
U 50 (-110)
|
|
Oct 24, 2025 10:00PM EDT
Boise State Broncos
Nevada Wolf Pack
10/24/25 10PM
BOISE
NEVADA
|
–
–
|
-1800
+850
|
-21 (-110)
+21 (-110)
|
O 50.5 (-105)
U 50.5 (-115)
|
|
Oct 25, 2025 12:00PM EDT
Virginia Cavaliers
North Carolina Tar Heels
10/25/25 12PM
UVA
UNC
|
–
–
|
-410
+305
|
-10.5 (-105)
+10.5 (-115)
|
O 52 (-105)
U 52 (-115)
|
|
Oct 25, 2025 12:00PM EDT
Bowling Green Falcons
Kent State Golden Flashes
10/25/25 12PM
BGREEN
KENT
|
–
–
|
-290
+240
|
-7 (-115)
+7 (-105)
|
O 48.5 (-110)
U 48.5 (-110)
|
|
Oct 25, 2025 12:00PM EDT
Rutgers Scarlet Knights
Purdue Boilermakers
10/25/25 12PM
RUT
PURDUE
|
–
–
|
-130
+110
|
-2.5 (-115)
+2.5 (-105)
|
O 58.5 (-110)
U 58.5 (-110)
|
|
Oct 25, 2025 12:00PM EDT
South Florida Bulls
Memphis Tigers
10/25/25 12PM
SFLA
MEMP
|
–
–
|
-200
+170
|
-4.5 (-110)
+4.5 (-110)
|
O 63.5 (-110)
U 63.5 (-110)
|
|
Oct 25, 2025 12:00PM EDT
UCLA Bruins
Indiana Hoosiers
10/25/25 12PM
UCLA
IND
|
–
–
|
+1100
-3500
|
+25.5 (-110)
-25.5 (-110)
|
O 55.5 (-110)
U 55.5 (-110)
|
|
Oct 25, 2025 12:00PM EDT
Northwestern Wildcats
Nebraska Cornhuskers
10/25/25 12PM
NWEST
NEB
|
–
–
|
+235
-285
|
+7 (-105)
-7 (-115)
|
O 43.5 (-110)
U 43.5 (-110)
|
|
Oct 25, 2025 12:00PM EDT
Ohio Bobcats
Eastern Michigan Eagles
10/25/25 12PM
OHIO
EMICH
|
–
–
|
-480
+350
|
-12.5 (-110)
+12.5 (-110)
|
O 59.5 (-115)
U 59.5 (-105)
|
|
Oct 25, 2025 12:00PM EDT
SMU Mustangs
Wake Forest Demon Deacons
10/25/25 12PM
SMU
WAKE
|
–
–
|
-175
+150
|
-3.5 (-105)
+3.5 (-115)
|
O 54 (-110)
U 54 (-110)
|
|
Oct 25, 2025 12:00PM EDT
Syracuse Orange
Georgia Tech Yellow Jackets
10/25/25 12PM
CUSE
GATECH
|
–
–
|
+600
-950
|
+17.5 (-110)
-17.5 (-110)
|
O 53.5 (-105)
U 53.5 (-115)
|
|
Oct 25, 2025 12:00PM EDT
App State Mountaineers
Old Dominion Monarchs
10/25/25 12PM
APPST
OLDDOM
|
–
–
|
-625
|
-14.5 (-105)
|
O 63 (-110)
U 63 (-110)
|
|
Oct 25, 2025 12:00PM EDT
Ole Miss Rebels
Oklahoma Sooners
10/25/25 12PM
OLEMISS
OKLA
|
–
–
|
+175
-210
|
+5 (-110)
-5 (-110)
|
O 54.5 (-110)
U 54.5 (-110)
|
|
Oct 25, 2025 12:00PM EDT
Kansas State Wildcats
Kansas Jayhawks
10/25/25 12PM
KSTATE
KANSAS
|
–
–
|
+130
-150
|
+3 (-110)
-3 (-110)
|
O 56.5 (-110)
U 56.5 (-110)
|
|
Oct 25, 2025 12:45PM EDT
Auburn Tigers
Arkansas Razorbacks
10/25/25 12:45PM
AUBURN
ARK
|
–
–
|
-105
-115
|
+1 (-110)
-1 (-110)
|
O 57 (-105)
U 57 (-115)
|
|
Oct 25, 2025 1:00PM EDT
Akron Zips
Buffalo Bulls
10/25/25 1PM
AKRON
BUFF
|
–
–
|
+285
-370
|
+9.5 (-110)
-9.5 (-110)
|
O 47 (-110)
U 47 (-110)
|
|
Oct 25, 2025 3:00PM EDT
UConn Huskies
Rice Owls
10/25/25 3PM
UCONN
RICE
|
–
–
|
-420
+315
|
-11 (-105)
+11 (-115)
|
O 49 (-110)
U 49 (-110)
|
|
Oct 25, 2025 3:00PM EDT
Utah State Aggies
New Mexico Lobos
10/25/25 3PM
UTAHST
NMEX
|
–
–
|
+130
-150
|
+3 (-110)
-3 (-110)
|
O 61.5 (-110)
U 61.5 (-110)
|
|
Oct 25, 2025 3:30PM EDT
Minnesota Golden Gophers
Iowa Hawkeyes
10/25/25 3:30PM
MINN
IOWA
|
–
–
|
+270
-340
|
+9.5 (-110)
-9.5 (-110)
|
O 39 (-110)
U 39 (-110)
|
|
Oct 25, 2025 3:30PM EDT
Alabama Crimson Tide
South Carolina Gamecocks
10/25/25 3:30PM
BAMA
SC
|
–
–
|
-510
+370
|
-12.5 (-110)
+12.5 (-110)
|
O 47.5 (-110)
U 47.5 (-110)
|
|
Oct 25, 2025 3:30PM EDT
BYU Cougars
Iowa State Cyclones
10/25/25 3:30PM
BYU
IOWAST
|
–
–
|
+120
-140
|
+2.5 (+105)
-2.5 (-125)
|
O 48.5 (-110)
U 48.5 (-110)
|
|
Oct 25, 2025 3:30PM EDT
Temple Owls
Tulsa Golden Hurricane
10/25/25 3:30PM
TEMPLE
TULSA
|
–
–
|
-225
+185
|
-6 (-110)
+6 (-110)
|
O 53.5 (-110)
U 53.5 (-110)
|
|
Oct 25, 2025 3:30PM EDT
Ball State Cardinals
Northern Illinois Huskies
10/25/25 3:30PM
BALLST
NILL
|
–
–
|
+180
-220
|
+5.5 (-110)
-5.5 (-110)
|
O 41 (-115)
U 41 (-105)
|
|
Oct 25, 2025 3:30PM EDT
Toledo Rockets
Washington State Cougars
10/25/25 3:30PM
TOLEDO
WASHST
|
–
–
|
-105
-115
|
+1 (-110)
-1 (-110)
|
O 46.5 (-110)
U 46.5 (-110)
|
|
Oct 25, 2025 3:30PM EDT
Florida Atlantic Owls
Navy Midshipmen
10/25/25 3:30PM
FAU
NAVY
|
–
–
|
+460
-675
|
+15 (-110)
-15 (-110)
|
O 62.5 (-110)
U 62.5 (-110)
|
|
Oct 25, 2025 3:30PM EDT
Illinois Fighting Illini
Washington Huskies
10/25/25 3:30PM
ILL
WASH
|
–
–
|
+165
-195
|
+4.5 (-110)
-4.5 (-110)
|
O 54 (-105)
U 54 (-115)
|
|
Oct 25, 2025 3:30PM EDT
Umass Minutemen
Central Michigan Chippewas
10/25/25 3:30PM
UMASS
CMICH
|
–
–
|
-750
|
-16 (-110)
|
O 47 (-110)
U 47 (-110)
|
|
Oct 25, 2025 3:30PM EDT
San Diego State Aztecs
Fresno State Bulldogs
10/25/25 3:30PM
SDGST
FRESNO
|
–
–
|
-150
+130
|
-3 (-110)
+3 (-110)
|
O 48 (-110)
U 48 (-110)
|
|
Oct 25, 2025 3:30PM EDT
Missouri Tigers
Vanderbilt Commodores
10/25/25 3:30PM
MIZZOU
VANDY
|
–
–
|
+115
-135
|
+2.5 (-105)
-2.5 (-115)
|
O 52 (-110)
U 52 (-110)
|
|
Oct 25, 2025 3:30PM EDT
NC State Wolfpack
Pittsburgh Panthers
10/25/25 3:30PM
NCST
PITT
|
–
–
|
+210
-250
|
+6.5 (-110)
-6.5 (-110)
|
O 57 (-110)
U 57 (-110)
|
|
Oct 25, 2025 3:30PM EDT
Western Michigan Broncos
Miami Ohio Redhawks
10/25/25 3:30PM
WMICH
MIAOH
|
–
–
|
+100
|
+1.5 (-115)
|
O 41 (-115)
U 41 (-105)
|
|
Oct 25, 2025 3:30PM EDT
UL Monroe Warhawks
USM Golden Eagles
10/25/25 3:30PM
MONROE
USM
|
–
–
|
+335
|
+11 (-110)
|
O 50.5 (-110)
U 50.5 (-110)
|
|
Oct 25, 2025 4:00PM EDT
Oklahoma State Cowboys
Texas Tech Red Raiders
10/25/25 4PM
OKLAST
TXTECH
|
–
–
|
+3000
-10000
|
+38.5 (-115)
-38.5 (-105)
|
O 56.5 (-110)
U 56.5 (-110)
|
|
Oct 25, 2025 4:00PM EDT
Baylor Bears
Cincinnati Bearcats
10/25/25 4PM
BAYLOR
CINCY
|
–
–
|
+160
-185
|
+4 (-110)
-4 (-110)
|
O 67 (-110)
U 67 (-110)
|
|
Oct 25, 2025 4:15PM EDT
Texas Longhorns
Mississippi State Bulldogs
10/25/25 4:15PM
TEXAS
MISSST
|
–
–
|
-260
+215
|
-7 (-105)
+7 (-115)
|
O 45 (-110)
U 45 (-110)
|
|
Oct 25, 2025 6:00PM EDT
TCU Horned Frogs
West Virginia Mountaineers
10/25/25 6PM
TCU
WVU
|
–
–
|
-675
+460
|
-15 (-110)
+15 (-110)
|
O 55 (-105)
U 55 (-115)
|
|
Oct 25, 2025 7:00PM EDT
Wisconsin Badgers
Oregon Ducks
10/25/25 7PM
WISC
OREG
|
–
–
|
|
+33.5 (-110)
-33.5 (-110)
|
O 44.5 (-110)
U 44.5 (-110)
|
|
Oct 25, 2025 7:00PM EDT
Louisiana Ragin Cajuns
Troy Trojans
10/25/25 7PM
UL
TROY
|
–
–
|
+260
-320
|
+8 (-110)
-8 (-110)
|
O 47.5 (-110)
U 47.5 (-110)
|
|
Oct 25, 2025 7:00PM EDT
Stanford Cardinal
Miami Hurricanes
10/25/25 7PM
STNFRD
MIAMI
|
–
–
|
+4000
-30000
|
+30 (-115)
-30 (-105)
|
O 45.5 (-110)
U 45.5 (-110)
|
|
Oct 25, 2025 7:00PM EDT
Georgia Southern Eagles
Arkansas State Red Wolves
10/25/25 7PM
GASO
ARKST
|
–
–
|
+100
-120
|
+1.5 (-110)
-1.5 (-110)
|
O 63.5 (-110)
U 63.5 (-110)
|
|
Oct 25, 2025 7:30PM EDT
Michigan Wolverines
Michigan State Spartans
10/25/25 7:30PM
MICH
MICHST
|
–
–
|
-625
+430
|
-14.5 (-105)
+14.5 (-115)
|
O 47.5 (-110)
U 47.5 (-110)
|
|
Oct 25, 2025 7:30PM EDT
Texas A&M Aggies
LSU Tigers
10/25/25 7:30PM
TEXAM
LSU
|
–
–
|
-135
+115
|
-2.5 (-115)
+2.5 (-105)
|
O 48 (-105)
U 48 (-115)
|
|
Oct 25, 2025 7:30PM EDT
Boston College Eagles
Louisville Cardinals
10/25/25 7:30PM
BC
LVILLE
|
–
–
|
+1100
-3300
|
+25 (-110)
-25 (-110)
|
O 55.5 (-105)
U 55.5 (-115)
|
|
Oct 25, 2025 7:30PM EDT
Colorado State Rams
Wyoming Cowboys
10/25/25 7:30PM
COLOST
WYO
|
–
–
|
+180
-220
|
+5.5 (-105)
-5.5 (-115)
|
O 46.5 (-110)
U 46.5 (-110)
|
|
Oct 25, 2025 7:45PM EDT
Tennessee Volunteers
Kentucky Wildcats
10/25/25 7:45PM
TENN
UK
|
–
–
|
-350
+275
|
-9.5 (-110)
+9.5 (-110)
|
O 54 (-115)
U 54 (-105)
|
|
Oct 25, 2025 8:00PM EDT
Houston Cougars
Arizona State Sun Devils
10/25/25 8PM
HOU
ARIZST
|
–
–
|
+250
-300
|
+7.5 (-115)
-7.5 (-105)
|
O 47 (-110)
U 47 (-110)
|
|
Oct 25, 2025 10:15PM EDT
Colorado Buffaloes
Utah Utes
10/25/25 10:15PM
COLO
UTAH
|
–
–
|
+425
-600
|
+14 (-115)
-14 (-105)
|
O 50 (-110)
U 50 (-110)
|
|
Oct 28, 2025 8:00PM EDT
James Madison Dukes
Texas State Bobcats
10/28/25 8PM
JMAD
TEXST
|
–
–
|
-275
+220
|
-7.5 (-104)
+7.5 (-118)
|
O 60.5 (-112)
U 60.5 (-108)
|
|
Oct 30, 2025 7:30PM EDT
Tulane Green Wave
UTSA Roadrunners
10/30/25 7:30PM
TULANE
UTSA
|
–
–
|
-200
+164
|
-5.5 (-110)
+5.5 (-110)
|
O 52.5 (-112)
U 52.5 (-108)
|
|
Nov 1, 2025 12:00PM EDT
Penn State Nittany Lions
Ohio State Buckeyes
11/1/25 12PM
PSU
OHIOST
|
–
–
|
+660
-1050
|
+17.5 (-115)
-17.5 (-105)
|
O 47.5 (-110)
U 47.5 (-110)
|
|
Nov 1, 2025 12:00PM EDT
Miami Hurricanes
SMU Mustangs
11/1/25 12PM
MIAMI
SMU
|
–
–
|
-430
+330
|
-10.5 (-110)
+10.5 (-110)
|
O 51.5 (-110)
U 51.5 (-110)
|
|
Nov 1, 2025 12:00PM EDT
Oklahoma Sooners
Tennessee Volunteers
11/1/25 12PM
OKLA
TENN
|
–
–
|
-105
-114
|
+1.5 (-114)
-1.5 (-106)
|
O 53.5 (-112)
U 53.5 (-108)
|
|
Nov 1, 2025 12:00PM EDT
Vanderbilt Commodores
Texas Longhorns
11/1/25 12PM
VANDY
TEXAS
|
–
–
|
+150
-182
|
+3.5 (-106)
-3.5 (-114)
|
O 45.5 (-110)
U 45.5 (-110)
|
|
Nov 1, 2025 3:30PM EDT
Georgia Bulldogs
Florida Gators
11/1/25 3:30PM
UGA
FLA
|
–
–
|
-300
+240
|
-7.5 (-110)
+7.5 (-110)
|
O 50.5 (-112)
U 50.5 (-108)
|
CFB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Missouri Tigers vs. Vanderbilt Commodores on October 25, 2025 at FirstBank Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our CFB odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
FSU@STNFRD | STNFRD +18 | 56.6% | 6 | WIN |
WASHST@UVA | WASHST +17.5 | 58.8% | 8 | WIN |
NEVADA@NMEX | NEVADA +13.5 | 57.8% | 7 | WIN |
TEXAS@UK | ARCH MANNING UNDER 1.5 PASS TD | 56.1% | 6 | WIN |
ARMY@TULANE | ARMY +10 | 55.3% | 5 | WIN |
SJST@UTAHST | SJST +4 | 54.4% | 4 | LOSS |
LVILLE@MIAMI | LVILLE +12.5 | 56.5% | 6 | WIN |
LVILLE@MIAMI | CJ DANIELS UNDER 4.5 RECEPTIONS | 54.4 | 4 | LOSS |
DEL@JAXST | DEL -2.5 | 57.6% | 6 | LOSS |
UTEP@SAMST | UTEP -2.5 | 53.9% | 3 | WIN |
FIU@WKY | FIU +10.5 | 54.6% | 4 | WIN |
ARKST@SALA | ARKST +7.5 | 54.5% | 4 | WIN |
ARKST@SALA | JAYLEN RAYNOR UNDER 40.5 LONGEST PASS COMP | 53.3% | 3 | WIN |
SJST@WYO | SJST -120 | 59.8% | 7 | LOSS |
UMASS@KENTST | KENTST -135 | 60.2% | 6 | WIN |
NOILL@EMICH | EMICH +2.5 | 53.9% | 3 | WIN |
BYU@ARIZ | ARIZ +2.5 | 54.2% | 3 | LOSS |
OKLA@TEXAS | OKLA +2.5 | 54.7% | 4 | LOSS |
NMEX@BOISE | NMEX +16.5 | 56.4% | 6 | WIN |
WAKE@OREGST | WAKE -2.5 | 56.7% | 6 | WIN |
ULMON@COASTAL | ULMON -2.5 | 56.8% | 6 | LOSS |
IOWA@WISC | WISC +4 | 54.8% | 4 | LOSS |
TOLEDO@BGREEN | TOLEDO -10 | 56.3% | 6 | LOSS |
SFLA@NOTEX | SFLA +2.5 | 54.3% | 4 | WIN |
FRESNO@COLOST | RICHIE ANDERSON III LONGEST RECEPTION UNDER 16.5 | 54.4% | 4 | LOSS |
JAXST@SAMST | SAMST +7.5 | 55.3% | 5 | WIN |
USM@GAS | GAS +3.5 | 57.4% | 7 | WIN |
LIB@UTEP | UTEP +2 | 54.5% | 4 | LOSS |
SALA@TROY | SALA -118 | 55.2% | 4 | LOSS |
TULSA@MEMP | MEMP -20.5 | 53.8% | 3 | WIN |
JMAD@GAST | GAST +20.5 | 54.6% | 4 | WIN |
WAKE@VATECH | VATECH -5.5 | 56.6% | 6 | LOSS |
UNLV@WYO | WYO +4.5 | 55.5% | 5 | LOSS |
PSU@UCLA | PSU -24.5 | 56.3% | 6 | LOSS |
TXSTSM@ARKST | TXSTSM -13 | 56.7% | 6 | LOSS |
UVA@LVILLE | ISAAC BROWN OVER 70.5 RUSH YDS | 56.6% | 6 | LOSS |
WVU@BYU | WVU +20.5 | 54.7% | 4 | WIN |
SAMST@NMEXST | SAMST -1.5 | 54.1% | 3 | LOSS |
EMICH@CMICH | CMICH -148 | 62.8% | 7 | WIN |
SDGST@NOILL | SDGST -118 | 55.7% | 3 | WIN |
BAMA@GEORGIA | GEORGIA -125 | 58.7% | 7 | LOSS |
TENN@MISSST | MISSST +7.5 | 54.3% | 4 | WIN |
UK@SC | SC -5.5 | 54.8% | 4 | WIN |
WKY@MIZZST | MIZZST +4.5 | 55.6% | 6 | LOSS |
JAXST@USM | USM -3.5 | 56.0% | 5 | WIN |
NMEXST@NMEX | NMEX -14.5 | 56.9% | 6 | WIN |
ARIZ@IOWAST | ROCCO BECHT UNDER 1.5 PASS TDS | 55.5% | 5 | WIN |
TCU@ARIZST | JOSH HOOVER PASS YDS UNDER 287.5 | 53.4% | 3 | WIN |
ARIZST@BAYLOR | BAYLOR -130 | 58.4% | 6 | LOSS |
WYO@COLO | WYO +13.5 | 54.1% | 3 | LOSS |
TULANE@OLEMISS | MISS -11.5 | 54.3% | 4 | WIN |