Syracuse vs SMU Prediction — AI Finds CAN'T MISS CFB Lines & Props (Oct 04)

Updated: 2025-09-27T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

Syracuse heads to Dallas on October 4, 2025 to face SMU in what looks like a challenging cross-league showdown that pits Syracuse’s resilience against SMU’s explosive offense and recent program momentum. With SMU expected to be a significant favorite, the Orange will need more than grit to compete — they’ll need to execute cleanly in all three phases to stay within range.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Oct 04, 2025

Start Time: 3:30 PM EST​

Venue: Gerald J. Ford Stadium​

Mustangs Record: (2-2)

Orange Record: (3-2)

OPENING ODDS

CUSE Moneyline: +505

SMU Moneyline: -719

CUSE Spread: +16.5

SMU Spread: -16.5

Over/Under: 58.5

CUSE
Betting Trends

  • Through early 2025, Syracuse has a modest ATS record of 2–1–1, a 66.7 % cover rate, suggesting they’ve occasionally exceeded expectations despite inconsistencies.

SMU
Betting Trends

  • SMU has struggled to cover big spreads, especially as a favorite; in recent non-conference matchups, they’ve faced criticism for failing to dominate and failing to clear large lines cleanly.

MATCHUP TRENDS

  • SMU opens this game as about a 13.5-point favorite over Syracuse, a margin that invites underdog interest if Syracuse can limit mistakes. Also, with SMU’s status as a newly minted ACC power and Syracuse’s underdog drag, the movement in the line — and how the public vs sharp money plays out — will be key betting dynamics to watch.

CUSE vs. SMU
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: R. Collins under 241.5 Passing Yards

LIVE CFB ODDS

CFB ODDS COMPARISON

WANT MORE AI PICKS?

VAULT
VS. SPREAD
325-240
VAULT
NET UNITS
(INCL VIG)
+395.4
VAULT
NET PROFIT
(INCL VIG)
$100/UNIT
$39,540
EXECUTIVE
VS. SPREAD
1593-1364
EXECUTIVE
NET UNITS
(INCL VIG)
+371.9
EXECUTIVE
NET PROFIT
(INCL VIG)
$100/UNIT
$37,192

AI SPORTS PICK PRODUCTS

Create a Free Account

‘Create an Account’ to Get Remi’s Picks Today.

Remi Finds New Picks

Remi calculates the probability a team will cover the line.

Remi Works 24/7

Remi uses this probability to assign units to each pick.

Get Remi's AI Picks

Get Remi’s Top AI Sports Picks sent direct to your inbox.

Syracuse vs SMU Prediction & Odds:
Free CFB Betting Insights for 10/4/25

The October 4, 2025 matchup between Syracuse and SMU at Gerald J. Ford Stadium in Dallas presents a fascinating clash between a traditional ACC program trying to reassert itself and a newer ACC entrant eager to prove it belongs among the league’s rising powers, and the dynamics of this game make it one of the more intriguing battles of the weekend. Syracuse enters with a mixed profile, showing flashes of explosiveness offensively and resilience in stretches, but also vulnerability when forced into negative game scripts, as evidenced by their 38–3 setback against Duke where turnovers, stalled drives, and inefficiency in the red zone crippled their chances of competing. Their quarterback has shown potential in extending plays and pushing the ball downfield, but protection breakdowns and inconsistency in timing routes have kept the Orange from maximizing their offensive ceiling, and on the road against SMU they will need near-perfect execution to sustain drives. The receiving corps has playmakers capable of creating separation, but drops and missed opportunities have been costly, and the offensive line will need to stand up against a Mustangs front designed to create havoc. Defensively, Syracuse has relied on aggressiveness, but overcommitting has led to costly breakdowns, and they cannot afford to give up chunk plays to a team like SMU that thrives on tempo and quick-strike drives. The Orange must focus on forcing long possessions, winning third downs, and keeping the game within reach deep into the second half to give themselves a shot at either an upset or a backdoor cover.

On the other side, SMU is embracing its moment in the ACC, entering undefeated with an offense tailored for fireworks under head coach Rhett Lashlee and quarterback Kevin Jennings, who has shown the ability to deliver on time and push the ball downfield with confidence. The Mustangs thrive when they play fast, spreading the ball across multiple weapons and keeping defenses off balance with a balanced run-pass approach that can overwhelm opponents when rhythm is established. At home, they will look to start fast, impose their tempo, and use their speed at wide receiver and running back to stress Syracuse’s defensive structure, which has been shaky against disciplined schemes. Defensively, SMU has been improved but still has a tendency to allow yardage in chunks, so red-zone defense and turnover creation will be key to preventing Syracuse from hanging around. Special teams could also be decisive, as SMU’s ability to flip field position or spark momentum with a return could be a dagger against a Syracuse squad that has struggled to recover from setbacks. From a betting perspective, SMU enters as a two-touchdown favorite, which reflects their offensive edge and home-field advantage, but Syracuse’s 2–1–1 ATS mark shows they have at times exceeded expectations and could prove dangerous if the Mustangs are sloppy with execution. Ultimately, this game feels like a test of composure and consistency: SMU will look to validate its rise by delivering a commanding win, while Syracuse will hope to frustrate the Mustangs with disciplined defense and opportunistic offense, and the outcome will hinge on whether the Orange can limit explosive plays or whether SMU’s speed and tempo overwhelm them in front of a raucous home crowd.

Syracuse Orange CFB Preview

The Syracuse Orange travel to Dallas on October 4, 2025 knowing they face one of their most difficult challenges of the season, as they step into a hostile environment against an SMU program that has built an identity around speed, tempo, and offensive fireworks, and for Syracuse the blueprint to compete will demand discipline, efficiency, and resilience across all phases. Offensively, the Orange must avoid the pitfalls that plagued them in their 38–3 loss to Duke, where turnovers and red-zone inefficiency killed momentum, and instead focus on clean execution, sustained drives, and protecting their quarterback from the Mustangs’ aggressive front. The offensive line will be under pressure to not only provide adequate pass protection but also create rushing lanes to keep SMU’s defense honest, and establishing balance early with their running backs will be critical to preventing the Mustangs from keying exclusively on the passing attack. Their quarterback has shown flashes of playmaking ability, but he must stay poised against blitz pressure and make quick decisions to avoid costly turnovers, while his receivers must rise to the occasion by winning contested catches and eliminating drops that have hampered consistency.

Defensively, Syracuse has been aggressive but sometimes undisciplined, and facing an SMU offense that thrives on quick strikes and tempo means the Orange must emphasize tackling in space, maintaining assignments, and preventing explosive plays that flip the game script early. Their front seven must win first downs to create long-yardage situations, while the secondary will need to be disciplined against a wide receiver group that can stretch the field vertically. Turnovers will likely be the great equalizer, and if Syracuse can steal possessions through interceptions or forced fumbles, they can shorten the field and keep their offense engaged. Special teams will also be vital, as road teams must avoid mistakes in coverage, penalties on returns, and missed kicks that give the opponent momentum, while any spark play—a blocked punt or long return—could provide the kind of swing Syracuse needs to remain competitive. From a betting standpoint, Syracuse enters with a modest 2–1–1 ATS record, showing they have at times surpassed expectations, and as a double-digit underdog they will once again have the chance to cover if they can avoid self-inflicted wounds and extend the game into the fourth quarter. Their formula is clear: play clean, win situational downs, limit SMU’s possessions, and stay within striking distance long enough to make the home favorite feel pressure. If the Orange can execute with consistency and take advantage of any mistakes from SMU, they have a realistic chance to keep this game closer than the oddsmakers project, and potentially deliver one of the season’s most surprising road upsets.

Syracuse heads to Dallas on October 4, 2025 to face SMU in what looks like a challenging cross-league showdown that pits Syracuse’s resilience against SMU’s explosive offense and recent program momentum. With SMU expected to be a significant favorite, the Orange will need more than grit to compete — they’ll need to execute cleanly in all three phases to stay within range. Syracuse vs SMU AI Prediction: Free CFB Betting Insights for Oct 04. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

SMU Mustangs CFB Preview

The SMU Mustangs return to Gerald J. Ford Stadium on October 4, 2025 with the confidence of an unbeaten start to their first full season as an ACC member and the expectation of putting on a show in front of their home crowd against a Syracuse team that has been inconsistent, and this matchup is as much about validating their rise as it is about protecting home turf. Offensively, SMU has all the pieces to stress Syracuse at every level, with quarterback Kevin Jennings commanding a scheme built on tempo, spacing, and vertical strikes, while their stable of running backs provides balance that keeps defenses from overcommitting to the pass. Their wide receiver corps has been electric, capable of turning routine catches into explosive plays, and at home with the crowd behind them, the Mustangs will look to jump out quickly, force Syracuse into a deficit, and dictate the pace of the game. Their offensive line has been quietly effective, creating pockets for Jennings and lanes for the run game, and they will need to stay sharp against a Syracuse front that, despite flaws, has been aggressive in trying to generate pressure.

Defensively, SMU has shown growth, but this game will test their ability to contain a Syracuse attack that, while inconsistent, has the talent to score in bunches if given rhythm, meaning the Mustangs must prioritize winning early downs, forcing third-and-long situations, and generating turnovers to flip momentum. Their secondary will be challenged by Syracuse’s receivers, but if their defensive line can collapse the pocket and prevent extended plays, they should be able to limit damage and get the ball back into the hands of their high-powered offense. Special teams, often the unsung factor, could play a decisive role: SMU must ensure clean coverage, win the field position battle, and potentially look for an explosive return or blocked kick to break the game open in a contest where they are favored by nearly two touchdowns. From a betting perspective, the Mustangs’ issue in recent years has been covering large spreads, as they sometimes build leads but allow late points or lapses to close the margin, and that history means they will need to sustain intensity for four quarters if they want to satisfy both fans and bettors. Their blueprint for success is simple yet demanding: start fast, lean on their offensive firepower, suffocate Syracuse’s drives with disciplined defense, and finish red-zone opportunities with touchdowns to prevent the Orange from hanging around. If SMU executes at their ceiling, they have the weapons and the crowd advantage to win comfortably, assert themselves as a true ACC force, and show they can not only win games but also handle the expectations of being a heavy home favorite.

Syracuse vs. SMU Prop Picks (AI)

AI algorithm Remi is pouring through tons of data on each team. In fact, anytime the Orange and Mustangs play there’s always several intriguing trends to key in on. Not to mention games played at Gerald J. Ford Stadium in Oct rarely follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: R. Collins under 241.5 Passing Yards

Syracuse vs. SMU Prediction (AI)

Remi Robot Icon

Remi, our AI sports wizard, has been pouring over millions of data from every angle between the Orange and Mustangs and using recursive machine learning and industry leading AI to boil down the data to a single cover probability.

Oddly enough, we’ve seen the AI has been most fixated on the unproportionally assigned emphasis human bettors often put on coaching factors between a Orange team going up against a possibly deflated Mustangs team. In reality, the true game analytics appear to reflect a strong lean against one Vegas line specifically.

Unlock this in-depth AI prediction and all of our CFB AI picks for FREE now.

Below is our current AI Syracuse vs SMU picks, computer picks Orange vs Mustangs, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
CFB 10/21 KENSAW@FIU UNLOCK THIS PICK 3 EXECUTIVE Locked EXECUTIVE
CFB 10/21 WKY@LATECH UNLOCK THIS PICK 2 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full CFB schedule

Orange Betting Trends

Through early 2025, Syracuse has a modest ATS record of 2–1–1, a 66.7 % cover rate, suggesting they’ve occasionally exceeded expectations despite inconsistencies.

Mustangs Betting Trends

SMU has struggled to cover big spreads, especially as a favorite; in recent non-conference matchups, they’ve faced criticism for failing to dominate and failing to clear large lines cleanly.

Orange vs. Mustangs Matchup Trends

SMU opens this game as about a 13.5-point favorite over Syracuse, a margin that invites underdog interest if Syracuse can limit mistakes. Also, with SMU’s status as a newly minted ACC power and Syracuse’s underdog drag, the movement in the line — and how the public vs sharp money plays out — will be key betting dynamics to watch.

Syracuse vs. SMU Game Info

Syracuse vs SMU starts on October 04, 2025 at 3:30 PM EST.

Venue: Gerald J. Ford Stadium.

Spread: SMU -16.5
Moneyline: Syracuse +505, SMU -719
Over/Under: 58.5

Syracuse: (3-2)  |  SMU: (2-2)

Remi's searched hard and found the best prop for this matchup: R. Collins under 241.5 Passing Yards. Prices move—always shop for the best number.

SMU opens this game as about a 13.5-point favorite over Syracuse, a margin that invites underdog interest if Syracuse can limit mistakes. Also, with SMU’s status as a newly minted ACC power and Syracuse’s underdog drag, the movement in the line — and how the public vs sharp money plays out — will be key betting dynamics to watch.

CUSE trend: Through early 2025, Syracuse has a modest ATS record of 2–1–1, a 66.7 % cover rate, suggesting they’ve occasionally exceeded expectations despite inconsistencies.

SMU trend: SMU has struggled to cover big spreads, especially as a favorite; in recent non-conference matchups, they’ve faced criticism for failing to dominate and failing to clear large lines cleanly.

See our latest CFB picks and odds pages for 2025 to compare prices before you bet.

Syracuse vs. SMU Odds

AI algorithm Remi is pouring through loads of stats on each team. In fact, anytime the Syracuse vs SMU trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme temps can often follow normal, predictable betting trends.

Syracuse vs SMU Opening Odds

CUSE Moneyline: +505
SMU Moneyline: -719
CUSE Spread: +16.5
SMU Spread: -16.5
Over/Under: 58.5

Syracuse vs SMU Live Odds

Games PTS ML SPR O/U
Oct 22, 2025 7:30PM EDT
MTSU Blue Raiders
Delaware Blue Hens
10/22/25 7:30PM
MTSU
DEL
 
-370
 
-9.5 (-110)
O 55.5 (-110)
U 55.5 (-110)
Oct 22, 2025 9:00PM EDT
Missouri State Bears
New Mexico State Aggies
10/22/25 9PM
MIZZST
NMEXST
-108
-108
-1.5 (-105)
+1.5 (-115)
O 51.5 (-110)
U 51.5 (-110)
Oct 23, 2025 7:30PM EDT
South Alabama Jaguars
Georgia State Panthers
10/23/25 7:30PM
SBAMA
GAST
-225
+185
-6.5 (-110)
+6.5 (-110)
O 55.5 (-112)
U 55.5 (-108)
Oct 24, 2025 7:00PM EDT
North Texas Mean Green
Charlotte 49ers
10/24/25 7PM
NOTEX
CHARLO
-4000
+1600
-26.5 (-112)
+26.5 (-108)
O 61.5 (-105)
U 61.5 (-115)
Oct 24, 2025 7:30PM EDT
California Golden Bears
Virginia Tech Hokies
10/24/25 7:30PM
CAL
VATECH
+164
-198
+4.5 (-108)
-4.5 (-112)
O 49.5 (-115)
U 49.5 (-105)
Oct 24, 2025 10:00PM EDT
Boise State Broncos
Nevada Wolf Pack
10/24/25 10PM
BOISE
NEVADA
-1800
+1000
-21 (-115)
+21 (-105)
O 50.5 (-112)
U 50.5 (-108)
Oct 25, 2025 12:00PM EDT
Virginia Cavaliers
North Carolina Tar Heels
10/25/25 12PM
UVA
UNC
-395
+310
-10.5 (-108)
+10.5 (-112)
O 51.5 (-110)
U 51.5 (-110)
Oct 25, 2025 12:00PM EDT
Bowling Green Falcons
Kent State Golden Flashes
10/25/25 12PM
BGREEN
KENT
-290
+235
-7.5 (-105)
+7.5 (-115)
O 48.5 (-108)
U 48.5 (-112)
Oct 25, 2025 12:00PM EDT
Rutgers Scarlet Knights
Purdue Boilermakers
10/25/25 12PM
RUT
PURDUE
-135
+114
-2.5 (-115)
+2.5 (-105)
O 58.5 (-112)
U 58.5 (-108)
Oct 25, 2025 12:00PM EDT
South Florida Bulls
Memphis Tigers
10/25/25 12PM
SFLA
MEMP
-205
+170
-4.5 (-112)
+4.5 (-108)
O 63.5 (-108)
U 63.5 (-112)
Oct 25, 2025 12:00PM EDT
UCLA Bruins
Indiana Hoosiers
10/25/25 12PM
UCLA
IND
+1400
-3200
+25.5 (-110)
-25.5 (-110)
O 54.5 (-115)
U 54.5 (-105)
Oct 25, 2025 12:00PM EDT
Northwestern Wildcats
Nebraska Cornhuskers
10/25/25 12PM
NWEST
NEB
+230
-285
+7 (-105)
-7 (-115)
O 43.5 (-110)
U 43.5 (-110)
Oct 25, 2025 12:00PM EDT
Ohio Bobcats
Eastern Michigan Eagles
10/25/25 12PM
OHIO
EMICH
-500
+380
-12.5 (-108)
+12.5 (-112)
O 59.5 (-110)
U 59.5 (-110)
Oct 25, 2025 12:00PM EDT
SMU Mustangs
Wake Forest Demon Deacons
10/25/25 12PM
SMU
WAKE
-180
+150
-3.5 (-108)
+3.5 (-112)
O 53.5 (-115)
U 53.5 (-105)
Oct 25, 2025 12:00PM EDT
Syracuse Orange
Georgia Tech Yellow Jackets
10/25/25 12PM
CUSE
GATECH
+600
-900
+17.5 (-110)
-17.5 (-110)
O 53.5 (-110)
U 53.5 (-110)
Oct 25, 2025 12:00PM EDT
App State Mountaineers
Old Dominion Monarchs
10/25/25 12PM
APPST
OLDDOM
 
-625
 
-14.5 (-108)
O 62.5 (-115)
U 62.5 (-105)
Oct 25, 2025 12:00PM EDT
Ole Miss Rebels
Oklahoma Sooners
10/25/25 12PM
OLEMISS
OKLA
+180
-218
+4.5 (-105)
-4.5 (-115)
O 54.5 (-108)
U 54.5 (-112)
Oct 25, 2025 12:00PM EDT
Kansas State Wildcats
Kansas Jayhawks
10/25/25 12PM
KSTATE
KANSAS
+130
-155
+3 (-112)
-3 (-108)
O 56.5 (-115)
U 56.5 (-105)
Oct 25, 2025 12:45PM EDT
Auburn Tigers
Arkansas Razorbacks
10/25/25 12:45PM
AUBURN
ARK
-105
-115
+1.5 (-115)
-1.5 (-105)
O 56.5 (-112)
U 56.5 (-108)
Oct 25, 2025 1:00PM EDT
Akron Zips
Buffalo Bulls
10/25/25 1PM
AKRON
BUFF
+310
-395
+9.5 (-110)
-9.5 (-110)
O 47.5 (-110)
U 47.5 (-110)
Oct 25, 2025 3:00PM EDT
UConn Huskies
Rice Owls
10/25/25 3PM
UCONN
RICE
-410
+320
-10.5 (-110)
+10.5 (-110)
O 49.5 (-105)
U 49.5 (-115)
Oct 25, 2025 3:00PM EDT
Utah State Aggies
New Mexico Lobos
10/25/25 3PM
UTAHST
NMEX
+130
-155
+3 (-112)
-3 (-108)
O 61.5 (-112)
U 61.5 (-108)
Oct 25, 2025 3:30PM EDT
Minnesota Golden Gophers
Iowa Hawkeyes
10/25/25 3:30PM
MINN
IOWA
+275
-345
+9.5 (-112)
-9.5 (-108)
O 39.5 (-108)
U 39.5 (-112)
Oct 25, 2025 3:30PM EDT
Alabama Crimson Tide
South Carolina Gamecocks
10/25/25 3:30PM
BAMA
SC
-485
+370
-12.5 (-110)
+12.5 (-110)
O 47.5 (-108)
U 47.5 (-112)
Oct 25, 2025 3:30PM EDT
BYU Cougars
Iowa State Cyclones
10/25/25 3:30PM
BYU
IOWAST
+124
-148
+2.5 (-102)
-2.5 (-118)
O 48.5 (-112)
U 48.5 (-108)
Oct 25, 2025 3:30PM EDT
Temple Owls
Tulsa Golden Hurricane
10/25/25 3:30PM
TEMPLE
TULSA
-238
+195
-6 (-112)
+6 (-108)
O 53.5 (-112)
U 53.5 (-108)
Oct 25, 2025 3:30PM EDT
Ball State Cardinals
Northern Illinois Huskies
10/25/25 3:30PM
BALLST
NILL
+180
-218
+5.5 (-112)
-5.5 (-108)
O 41.5 (-105)
U 41.5 (-115)
Oct 25, 2025 3:30PM EDT
Toledo Rockets
Washington State Cougars
10/25/25 3:30PM
TOLEDO
WASHST
-102
-118
+1.5 (-115)
-1.5 (-105)
O 46.5 (-108)
U 46.5 (-112)
Oct 25, 2025 3:30PM EDT
Florida Atlantic Owls
Navy Midshipmen
10/25/25 3:30PM
FAU
NAVY
+455
-625
+15.5 (-108)
-15.5 (-112)
O 62.5 (-112)
U 62.5 (-108)
Oct 25, 2025 3:30PM EDT
Illinois Fighting Illini
Washington Huskies
10/25/25 3:30PM
ILL
WASH
+164
-198
+4.5 (-110)
-4.5 (-110)
O 53.5 (-115)
U 53.5 (-105)
Oct 25, 2025 3:30PM EDT
Umass Minutemen
Central Michigan Chippewas
10/25/25 3:30PM
UMASS
CMICH
 
-700
 
-16.5 (-108)
O 46.5 (-115)
U 46.5 (-105)
Oct 25, 2025 3:30PM EDT
San Diego State Aztecs
Fresno State Bulldogs
10/25/25 3:30PM
SDGST
FRESNO
-155
+130
-3 (-110)
+3 (-110)
O 47.5 (-115)
U 47.5 (-105)
Oct 25, 2025 3:30PM EDT
Missouri Tigers
Vanderbilt Commodores
10/25/25 3:30PM
MIZZOU
VANDY
+114
-135
+2.5 (-110)
-2.5 (-110)
O 51.5 (-115)
U 51.5 (-105)
Oct 25, 2025 3:30PM EDT
NC State Wolfpack
Pittsburgh Panthers
10/25/25 3:30PM
NCST
PITT
+205
-250
+6.5 (-108)
-6.5 (-112)
O 56.5 (-110)
U 56.5 (-110)
Oct 25, 2025 3:30PM EDT
Western Michigan Broncos
Miami Ohio Redhawks
10/25/25 3:30PM
WMICH
MIAOH
+102
 
+1.5 (-110)
 
O 41.5 (-105)
U 41.5 (-115)
Oct 25, 2025 3:30PM EDT
UL Monroe Warhawks
USM Golden Eagles
10/25/25 3:30PM
MONROE
USM
+340
 
+10.5 (-105)
 
O 50.5 (-112)
U 50.5 (-108)
Oct 25, 2025 4:00PM EDT
Oklahoma State Cowboys
Texas Tech Red Raiders
10/25/25 4PM
OKLAST
TXTECH
+2800
-10000
+38.5 (-115)
-38.5 (-105)
O 56.5 (-108)
U 56.5 (-112)
Oct 25, 2025 4:00PM EDT
Baylor Bears
Cincinnati Bearcats
10/25/25 4PM
BAYLOR
CINCY
+154
-185
+4.5 (-110)
-4.5 (-110)
O 66.5 (-115)
U 66.5 (-105)
Oct 25, 2025 4:15PM EDT
Texas Longhorns
Mississippi State Bulldogs
10/25/25 4:15PM
TEXAS
MISSST
-270
+220
-7 (-105)
+7 (-115)
O 44.5 (-115)
U 44.5 (-105)
Oct 25, 2025 6:00PM EDT
TCU Horned Frogs
West Virginia Mountaineers
10/25/25 6PM
TCU
WVU
-650
+470
-15.5 (-110)
+15.5 (-110)
O 54.5 (-118)
U 54.5 (-102)
Oct 25, 2025 7:00PM EDT
Wisconsin Badgers
Oregon Ducks
10/25/25 7PM
WISC
OREG
 
 
+33.5 (-108)
-33.5 (-112)
O 44.5 (-112)
U 44.5 (-108)
Oct 25, 2025 7:00PM EDT
Louisiana Ragin Cajuns
Troy Trojans
10/25/25 7PM
UL
TROY
+280
-355
+8.5 (-108)
-8.5 (-112)
O 47.5 (-110)
U 47.5 (-110)
Oct 25, 2025 7:00PM EDT
Stanford Cardinal
Miami Hurricanes
10/25/25 7PM
STNFRD
MIAMI
+4000
-30000
+30.5 (-115)
-30.5 (-105)
O 45.5 (-105)
U 45.5 (-115)
Oct 25, 2025 7:00PM EDT
Georgia Southern Eagles
Arkansas State Red Wolves
10/25/25 7PM
GASO
ARKST
+100
-120
+1.5 (-110)
-1.5 (-110)
O 63.5 (-105)
U 63.5 (-115)
Oct 25, 2025 7:30PM EDT
Michigan Wolverines
Michigan State Spartans
10/25/25 7:30PM
MICH
MICHST
-625
+455
-14.5 (-105)
+14.5 (-115)
O 47.5 (-115)
U 47.5 (-105)
Oct 25, 2025 7:30PM EDT
Texas A&M Aggies
LSU Tigers
10/25/25 7:30PM
TEXAM
LSU
-142
+120
-2.5 (-115)
+2.5 (-105)
O 47.5 (-115)
U 47.5 (-105)
Oct 25, 2025 7:30PM EDT
Boston College Eagles
Louisville Cardinals
10/25/25 7:30PM
BC
LVILLE
+1400
-3200
+25.5 (-110)
-25.5 (-110)
O 55.5 (-102)
U 55.5 (-118)
Oct 25, 2025 7:30PM EDT
Colorado State Rams
Wyoming Cowboys
10/25/25 7:30PM
COLOST
WYO
+180
-218
+5.5 (-110)
-5.5 (-110)
O 46.5 (-112)
U 46.5 (-108)
Oct 25, 2025 7:45PM EDT
Tennessee Volunteers
Kentucky Wildcats
10/25/25 7:45PM
TENN
UK
-345
+275
-9.5 (-108)
+9.5 (-112)
O 54.5 (-110)
U 54.5 (-110)
Oct 25, 2025 8:00PM EDT
Houston Cougars
Arizona State Sun Devils
10/25/25 8PM
HOU
ARIZST
+230
-285
+7.5 (-115)
-7.5 (-105)
O 46.5 (-115)
U 46.5 (-105)
Oct 25, 2025 10:15PM EDT
Colorado Buffaloes
Utah Utes
10/25/25 10:15PM
COLO
UTAH
+410
-550
+13.5 (-110)
-13.5 (-110)
O 49.5 (-112)
U 49.5 (-108)
Oct 28, 2025 8:00PM EDT
James Madison Dukes
Texas State Bobcats
10/28/25 8PM
JMAD
TEXST
-275
+220
-7.5 (-104)
+7.5 (-118)
O 60.5 (-112)
U 60.5 (-108)
Oct 30, 2025 7:30PM EDT
Tulane Green Wave
UTSA Roadrunners
10/30/25 7:30PM
TULANE
UTSA
-200
+164
-5.5 (-110)
+5.5 (-110)
O 52.5 (-112)
U 52.5 (-108)
Nov 1, 2025 12:00PM EDT
Penn State Nittany Lions
Ohio State Buckeyes
11/1/25 12PM
PSU
OHIOST
+660
-1050
+17.5 (-115)
-17.5 (-105)
O 47.5 (-110)
U 47.5 (-110)
Nov 1, 2025 12:00PM EDT
Miami Hurricanes
SMU Mustangs
11/1/25 12PM
MIAMI
SMU
-430
+330
-10.5 (-110)
+10.5 (-110)
O 51.5 (-110)
U 51.5 (-110)
Nov 1, 2025 12:00PM EDT
Oklahoma Sooners
Tennessee Volunteers
11/1/25 12PM
OKLA
TENN
-105
-114
+1.5 (-114)
-1.5 (-106)
O 53.5 (-112)
U 53.5 (-108)
Nov 1, 2025 12:00PM EDT
Vanderbilt Commodores
Texas Longhorns
11/1/25 12PM
VANDY
TEXAS
+150
-182
+3.5 (-106)
-3.5 (-114)
O 45.5 (-110)
U 45.5 (-110)
Nov 1, 2025 3:30PM EDT
Georgia Bulldogs
Florida Gators
11/1/25 3:30PM
UGA
FLA
-300
+240
-7.5 (-110)
+7.5 (-110)
O 50.5 (-112)
U 50.5 (-108)

CFB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Syracuse Orange vs. SMU Mustangs on October 04, 2025 at Gerald J. Ford Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our CFB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
FSU@STNFRD STNFRD +18 56.6% 6 WIN
WASHST@UVA WASHST +17.5 58.8% 8 WIN
NEVADA@NMEX NEVADA +13.5 57.8% 7 WIN
TEXAS@UK ARCH MANNING UNDER 1.5 PASS TD 56.1% 6 WIN
ARMY@TULANE ARMY +10 55.3% 5 WIN
SJST@UTAHST SJST +4 54.4% 4 LOSS
LVILLE@MIAMI LVILLE +12.5 56.5% 6 WIN
LVILLE@MIAMI CJ DANIELS UNDER 4.5 RECEPTIONS 54.4 4 LOSS
DEL@JAXST DEL -2.5 57.6% 6 LOSS
UTEP@SAMST UTEP -2.5 53.9% 3 WIN
FIU@WKY FIU +10.5 54.6% 4 WIN
ARKST@SALA ARKST +7.5 54.5% 4 WIN
ARKST@SALA JAYLEN RAYNOR UNDER 40.5 LONGEST PASS COMP 53.3% 3 WIN
SJST@WYO SJST -120 59.8% 7 LOSS
UMASS@KENTST KENTST -135 60.2% 6 WIN
NOILL@EMICH EMICH +2.5 53.9% 3 WIN
BYU@ARIZ ARIZ +2.5 54.2% 3 LOSS
OKLA@TEXAS OKLA +2.5 54.7% 4 LOSS
NMEX@BOISE NMEX +16.5 56.4% 6 WIN
WAKE@OREGST WAKE -2.5 56.7% 6 WIN
ULMON@COASTAL ULMON -2.5 56.8% 6 LOSS
IOWA@WISC WISC +4 54.8% 4 LOSS
TOLEDO@BGREEN TOLEDO -10 56.3% 6 LOSS
SFLA@NOTEX SFLA +2.5 54.3% 4 WIN
FRESNO@COLOST RICHIE ANDERSON III LONGEST RECEPTION UNDER 16.5 54.4% 4 LOSS
JAXST@SAMST SAMST +7.5 55.3% 5 WIN
USM@GAS GAS +3.5 57.4% 7 WIN
LIB@UTEP UTEP +2 54.5% 4 LOSS
SALA@TROY SALA -118 55.2% 4 LOSS
TULSA@MEMP MEMP -20.5 53.8% 3 WIN
JMAD@GAST GAST +20.5 54.6% 4 WIN
WAKE@VATECH VATECH -5.5 56.6% 6 LOSS
UNLV@WYO WYO +4.5 55.5% 5 LOSS
PSU@UCLA PSU -24.5 56.3% 6 LOSS
TXSTSM@ARKST TXSTSM -13 56.7% 6 LOSS
UVA@LVILLE ISAAC BROWN OVER 70.5 RUSH YDS 56.6% 6 LOSS
WVU@BYU WVU +20.5 54.7% 4 WIN
SAMST@NMEXST SAMST -1.5 54.1% 3 LOSS
EMICH@CMICH CMICH -148 62.8% 7 WIN
SDGST@NOILL SDGST -118 55.7% 3 WIN
BAMA@GEORGIA GEORGIA -125 58.7% 7 LOSS
TENN@MISSST MISSST +7.5 54.3% 4 WIN
UK@SC SC -5.5 54.8% 4 WIN
WKY@MIZZST MIZZST +4.5 55.6% 6 LOSS
JAXST@USM USM -3.5 56.0% 5 WIN
NMEXST@NMEX NMEX -14.5 56.9% 6 WIN
ARIZ@IOWAST ROCCO BECHT UNDER 1.5 PASS TDS 55.5% 5 WIN
TCU@ARIZST JOSH HOOVER PASS YDS UNDER 287.5 53.4% 3 WIN
ARIZST@BAYLOR BAYLOR -130 58.4% 6 LOSS
WYO@COLO WYO +13.5 54.1% 3 LOSS
TULANE@OLEMISS MISS -11.5 54.3% 4 WIN