Indiana vs Notre Dame Prediction — AI Finds CAN'T MISS CFB Lines & Props (Dec 20)

Updated: 2024-12-13T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Indiana Hoosiers (11-1) will face the Notre Dame Fighting Irish (11-1) in the first round of the College Football Playoff on December 20, 2024, at Notre Dame Stadium in South Bend, Indiana. This in-state showdown marks a significant moment in both programs’ histories, as they vie for a spot in the quarterfinals.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Dec 20, 2024

Start Time: 9:00 PM EST​

Venue: Notre Dame Stadium​

Fighting Irish Record: (11-1)

Hoosiers Record: (8-2)

OPENING ODDS

IND Moneyline: +242

ND Moneyline: -301

IND Spread: +7.5

ND Spread: -7.5

Over/Under: 50.5

IND
Betting Trends

  • Indiana has been strong against the spread (ATS) this season, achieving a 9-3 record. Notably, the Hoosiers have covered the spread in four of their last five games, indicating a strong finish to their regular season.

ND
Betting Trends

  • Notre Dame holds a 7-5 ATS record for the season. The Fighting Irish have been particularly effective at home, covering the spread in five of their six games at Notre Dame Stadium.

MATCHUP TRENDS

  • An interesting ATS statistic is that the total has gone under in eight of Notre Dame’s 12 games this season, suggesting a trend toward lower-scoring affairs. Conversely, Indiana’s games have seen the total go over in seven of their 12 contests, indicating a propensity for higher-scoring games.

IND vs. ND
Best Prop Bet

  • Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.

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Indiana vs Notre Dame Prediction & Odds:
Free CFB Betting Insights for 12/20/24

The College Football Playoff first-round matchup between the Indiana Hoosiers and the Notre Dame Fighting Irish is set to be a thrilling contest between two in-state rivals. Both teams enter the game with identical 11-1 records, showcasing their prowess throughout the season. Notre Dame, under head coach Marcus Freeman, has demonstrated a balanced attack and a stout defense, while Indiana, led by head coach Curt Cignetti, has enjoyed a historic season, marking one of the best in the program’s history. Offensively, Notre Dame has been efficient, averaging 35.4 points per game. Quarterback Riley Leonard has been instrumental, passing for over 2,800 yards and 24 touchdowns, while also contributing on the ground with 400 rushing yards and six touchdowns. His dual-threat capability poses a significant challenge to opposing defenses. The running game is anchored by Audric Estimé, who has rushed for 1,200 yards and 14 touchdowns, providing a consistent and powerful ground attack. The receiving corps, led by Deion Colzie with 800 receiving yards and eight touchdowns, offers reliable targets, complemented by tight end Mitchell Evans, who has been effective in both blocking and receiving roles. Defensively, the Fighting Irish have been formidable, allowing just 18.3 points per game. Linebacker JD Bertrand leads the team in tackles, showcasing exceptional field awareness and tackling ability. The defensive line, featuring Isaiah Foskey, has been effective in pressuring quarterbacks, contributing to the team’s 30 sacks this season. The secondary, led by cornerback Cam Hart, has been opportunistic, recording 12 interceptions and limiting big plays.

Indiana’s offense has been prolific, averaging 37.2 points per game. Quarterback Brendan Sorsby has emerged as a dynamic playmaker, throwing for over 3,000 yards and 28 touchdowns, while adding 500 rushing yards and seven touchdowns. Running back Jaylin Lucas complements the aerial attack with 1,100 rushing yards and 12 touchdowns, utilizing his speed and agility to exploit defenses. Wide receiver Cam Camper leads the team with 900 receiving yards and nine touchdowns, providing a deep threat and reliable hands. The offensive line has been solid, allowing Sorsby time to make plays and opening lanes for the running game. Defensively, the Hoosiers allow 21.5 points per game. Linebacker Aaron Casey has been a standout, leading the team in tackles and serving as a defensive anchor. The defensive line, with players like Andre Carter, has been effective in stopping the run and generating pressure, contributing to the team’s 25 sacks. The secondary, led by safety Noah Pierre, has been resilient, recording 10 interceptions and providing tight coverage. Special teams could play a pivotal role in this matchup. Notre Dame’s kicker, Blake Grupe, has been reliable, converting 85% of his field goal attempts, including several from beyond 40 yards. The return game, featuring Chris Tyree, has the potential to shift field position favorably. Indiana’s special teams have also been solid, with kicker Charles Campbell making 80% of his field goals and the coverage units effectively limiting opponents’ return opportunities. This game marks a significant chapter in the rivalry between Notre Dame and Indiana, with the stakes higher than ever in the College Football Playoff. The contrasting styles—Notre Dame’s balanced offense and stout defense against Indiana’s high-powered offense and resilient defense—set the stage for an engaging and competitive matchup. Both teams are eager to advance, and their performances will be closely watched by fans and analysts alike.

Indiana Hoosiers CFB Preview

The Indiana Hoosiers enter the College Football Playoff with a historic 11-1 record, marking their first appearance in the playoff under head coach Curt Cignetti. This season represents a remarkable turnaround for the program, as the Hoosiers have emerged as a legitimate contender on the national stage. Facing Notre Dame in the first round presents both a challenge and an opportunity to solidify their place among college football’s elite. Offensively, Indiana has been dynamic, averaging 37.2 points per game. Quarterback Brendan Sorsby has been the catalyst for the team’s success, throwing for over 3,000 yards and 28 touchdowns while adding 500 rushing yards and seven touchdowns on the ground. Sorsby’s dual-threat ability makes him a difficult matchup for opposing defenses, as he can extend plays with his legs and deliver accurate throws under pressure. Running back Jaylin Lucas has been a key contributor to Indiana’s offensive production, rushing for 1,100 yards and 12 touchdowns. Lucas’s speed and agility allow him to break big plays and gain critical yardage in tight situations. The offensive line has been a reliable unit, providing Sorsby with the protection he needs and creating running lanes for Lucas. The receiving corps is led by wide receiver Cam Camper, who has recorded 900 receiving yards and nine touchdowns this season. Camper’s ability to make contested catches and stretch the field has made him a favorite target for Sorsby. Supporting Camper are wide receivers Donaven McCulley and E.J. Williams, both of whom have provided valuable contributions with key receptions and the ability to exploit mismatches. Defensively, the Hoosiers allow 21.5 points per game, with a unit that has shown resilience throughout the season. Linebacker Aaron Casey has been the standout performer, leading the team in tackles and serving as the anchor of the defense. Casey’s ability to read plays and make decisive stops has been crucial in limiting opposing offenses. The defensive line, featuring Andre Carter, has been effective at generating pressure, recording 25 sacks as a team. Carter’s ability to disrupt plays in the backfield has been a key factor in the Hoosiers’ defensive success. The secondary, led by safety Noah Pierre, has been opportunistic, recording 10 interceptions and providing tight coverage against opposing passing attacks. Special teams have also been a strength for Indiana, with kicker Charles Campbell converting 80% of his field goal attempts and consistently delivering in high-pressure situations. The return game, led by Lucas, has provided sparks throughout the season, often giving the offense favorable field position. As Indiana prepares to face Notre Dame, their game plan will revolve around utilizing Sorsby’s dual-threat capabilities and establishing the run with Lucas. Defensively, the Hoosiers aim to contain Riley Leonard and limit the effectiveness of Audric Estimé in the ground game. Forcing turnovers and capitalizing on scoring opportunities will be critical for Indiana to pull off the upset. This game represents a defining moment for Indiana football, as they seek to prove their legitimacy on the national stage. With their high-powered offense and resilient defense, the Hoosiers are poised to compete fiercely against Notre Dame in what promises to be an electrifying playoff matchup.

The Indiana Hoosiers (11-1) will face the Notre Dame Fighting Irish (11-1) in the first round of the College Football Playoff on December 20, 2024, at Notre Dame Stadium in South Bend, Indiana. This in-state showdown marks a significant moment in both programs’ histories, as they vie for a spot in the quarterfinals. Indiana vs Notre Dame AI Prediction: Free CFB Betting Insights for Dec 20. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Notre Dame Fighting Irish CFB Preview

The Notre Dame Fighting Irish enter the College Football Playoff with an impressive 11-1 record, reflecting a season marked by resilience and consistent performance. Under the leadership of head coach Marcus Freeman, the team has showcased a balanced offensive attack complemented by a formidable defense, positioning them as strong contenders in the playoff landscape. Offensively, Notre Dame has been efficient, averaging 35.4 points per game. Quarterback Riley Leonard has been a pivotal figure, amassing over 2,800 passing yards and 24 touchdowns. His dual-threat capability is further evidenced by his 400 rushing yards and six touchdowns, making him a versatile asset in the offensive scheme. Leonard’s poise in the pocket and ability to extend plays with his legs have been instrumental in the team’s success. The ground game is spearheaded by running back Audric Estimé, who has accumulated 1,200 rushing yards and 14 touchdowns. Estimé’s combination of power and agility allows him to navigate through defenses effectively, providing a reliable option in short-yardage and goal-line situations. The offensive line has been a cornerstone of the team’s success, offering robust protection for Leonard and creating substantial running lanes for Estimé. In the receiving department, Deion Colzie stands out with 800 receiving yards and eight touchdowns. His ability to create separation and secure contested catches makes him a valuable target in critical situations. Tight end Mitchell Evans has also been a significant contributor, particularly in the red zone, where his size and catching ability have added another dimension to the offense. Complementing the primary targets are wide receivers Tobias Merriweather and Jayden Thomas, both of whom have provided key receptions throughout the season. Defensively, Notre Dame has been one of the top units in the nation, allowing just 18.3 points per game. Linebacker JD Bertrand has been the leader of the defense, showcasing exceptional field awareness and the ability to make crucial tackles. Bertrand’s leadership and consistency have set the tone for a disciplined defensive unit. The defensive line, anchored by Isaiah Foskey, has been effective at pressuring quarterbacks and disrupting opposing offenses. Foskey’s six sacks lead the team, and his presence often draws double teams, creating opportunities for other defenders to make plays. The secondary, led by cornerback Cam Hart, has been opportunistic, recording 12 interceptions and limiting big plays through the air. Hart’s ability to match up against opposing teams’ top receivers has been a critical factor in Notre Dame’s defensive success. Special teams have been another area of strength for the Fighting Irish. Kicker Blake Grupe has been reliable, converting 85% of his field goal attempts, including several from beyond 40 yards. Punter Bryce McFerson has consistently flipped field position, pinning opponents deep in their territory. Return specialist Chris Tyree has added an explosive element to the special teams unit, providing the potential for game-changing plays. Heading into the matchup against Indiana, Notre Dame’s game plan will focus on executing a balanced offensive attack while maintaining defensive discipline. Establishing the run with Audric Estimé will be crucial, as it sets up play-action opportunities for Leonard to exploit Indiana’s secondary. Defensively, the Fighting Irish will aim to contain Indiana’s dual-threat quarterback Brendan Sorsby and limit the effectiveness of running back Jaylin Lucas. This game represents a significant opportunity for Notre Dame to showcase their strength and advance in the College Football Playoff. The Fighting Irish are determined to capitalize on their home-field advantage and deliver a statement performance. With their balanced offense, dominant defense, and reliable special teams, Notre Dame is well-positioned to compete against a high-powered Indiana team. A victory in this playoff matchup would mark a major milestone for head coach Marcus Freeman and solidify Notre Dame’s place among the nation’s elite programs. The team’s preparation and execution will be critical as they face a talented Indiana squad eager to pull off an upset. Fans can expect Notre Dame to bring their best effort in what promises to be a hard-fought and memorable game at Notre Dame Stadium.

Indiana vs. Notre Dame Prop Picks (AI)

Remi is pouring through loads of stats on each team. In fact, anytime the Hoosiers and Fighting Irish play there’s always several intriguing trends to key in on. Not to mention games played at Notre Dame Stadium in Dec seemingly never follow normal, predictable betting trends.
Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.

Indiana vs. Notre Dame Prediction (AI)

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Remi, our AI sports wizard, has been pouring over millions of data from every angle between the Hoosiers and Fighting Irish and using recursive machine learning and cutting-edge AI to examine the data to a single cover probability.

Oddly enough, we’ve seen the AI has been most keyed in on the linear correlation of weight emotional bettors often put on player performance factors between a Hoosiers team going up against a possibly strong Fighting Irish team. We’ve found the true game analytics might reflect a moderate lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our CFB AI picks for FREE now.

Below is our current AI Indiana vs Notre Dame picks, computer picks Hoosiers vs Fighting Irish, best bets, model edges, confidence ratings.

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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full CFB schedule

Hoosiers Betting Trends

Indiana has been strong against the spread (ATS) this season, achieving a 9-3 record. Notably, the Hoosiers have covered the spread in four of their last five games, indicating a strong finish to their regular season.

Fighting Irish Betting Trends

Notre Dame holds a 7-5 ATS record for the season. The Fighting Irish have been particularly effective at home, covering the spread in five of their six games at Notre Dame Stadium.

Hoosiers vs. Fighting Irish Matchup Trends

An interesting ATS statistic is that the total has gone under in eight of Notre Dame’s 12 games this season, suggesting a trend toward lower-scoring affairs. Conversely, Indiana’s games have seen the total go over in seven of their 12 contests, indicating a propensity for higher-scoring games.

Indiana vs. Notre Dame Game Info

Indiana vs Notre Dame starts on December 20, 2024 at 9:00 PM EST.

Spread: Notre Dame -7.5
Moneyline: Indiana +242, Notre Dame -301
Over/Under: 50.5

Indiana: (8-2)  |  Notre Dame: (11-1)

Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.. Prices move—always shop for the best number.

An interesting ATS statistic is that the total has gone under in eight of Notre Dame’s 12 games this season, suggesting a trend toward lower-scoring affairs. Conversely, Indiana’s games have seen the total go over in seven of their 12 contests, indicating a propensity for higher-scoring games.

IND trend: Indiana has been strong against the spread (ATS) this season, achieving a 9-3 record. Notably, the Hoosiers have covered the spread in four of their last five games, indicating a strong finish to their regular season.

ND trend: Notre Dame holds a 7-5 ATS record for the season. The Fighting Irish have been particularly effective at home, covering the spread in five of their six games at Notre Dame Stadium.

See our latest CFB picks and odds pages for 2024 to compare prices before you bet.

Indiana vs. Notre Dame Odds

Remi is pouring through tons of data points on each player. In fact, anytime the Indiana vs Notre Dame trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme hostile environments can often follow normal, predictable betting trends.

Indiana vs Notre Dame Opening Odds

IND Moneyline: +242
ND Moneyline: -301
IND Spread: +7.5
ND Spread: -7.5
Over/Under: 50.5

Indiana vs Notre Dame Live Odds

Games PTS ML SPR O/U
Oct 21, 2025 7:00PM EDT
Kennesaw State Owls
FIU Panthers
10/21/25 7PM
KENSAW
FIU
-154
 
-3.5 (-104)
 
O 49.5 (-110)
U 49.5 (-110)
Oct 21, 2025 7:30PM EDT
Western Kentucky Hilltoppers
Louisiana Tech Bulldogs
10/21/25 7:30PM
WKY
LATECH
+134
-158
+3.5 (-114)
-3.5 (-106)
O 50.5 (-110)
U 50.5 (-110)
Oct 22, 2025 7:30PM EDT
MTSU Blue Raiders
Delaware Blue Hens
10/22/25 7:30PM
MTSU
DEL
 
-350
 
-8.5 (-118)
O 54.5 (-118)
U 54.5 (-104)
Oct 22, 2025 9:00PM EDT
Missouri State Bears
New Mexico State Aggies
10/22/25 9PM
MIZZST
NMEXST
-118
+100
-1.5 (-110)
+1.5 (-110)
O 51.5 (-112)
U 51.5 (-108)
Oct 23, 2025 7:30PM EDT
South Alabama Jaguars
Georgia State Panthers
10/23/25 7:30PM
SBAMA
GAST
-220
+188
-6.5 (-110)
+6.5 (-110)
O 55.5 (-110)
U 55.5 (-110)
Oct 24, 2025 7:00PM EDT
North Texas Mean Green
Charlotte 49ers
10/24/25 7PM
NOTEX
CHARLO
-4000
+1400
-27.5 (-102)
+27.5 (-120)
O 60.5 (-110)
U 60.5 (-110)
Oct 24, 2025 7:30PM EDT
California Golden Bears
Virginia Tech Hokies
10/24/25 7:30PM
CAL
VATECH
+158
-192
+4.5 (-110)
-4.5 (-110)
O 50.5 (-110)
U 50.5 (-110)
Oct 24, 2025 10:00PM EDT
Boise State Broncos
Nevada Wolf Pack
10/24/25 10PM
BOISE
NEVADA
-3000
+1200
-21.5 (-114)
+21.5 (-106)
O 50.5 (-110)
U 50.5 (-110)
Oct 25, 2025 12:00PM EDT
Virginia Cavaliers
North Carolina Tar Heels
10/25/25 12PM
UVA
UNC
-375
+290
-10.5 (-105)
+10.5 (-115)
O 52.5 (-105)
U 52.5 (-115)
Oct 25, 2025 12:00PM EDT
Bowling Green Falcons
Kent State Golden Flashes
10/25/25 12PM
BGREEN
KENT
-315
+250
-8.5 (-110)
+8.5 (-110)
O 48.5 (-110)
U 48.5 (-110)
Oct 25, 2025 12:00PM EDT
Rutgers Scarlet Knights
Purdue Boilermakers
10/25/25 12PM
RUT
PURDUE
-134
+108
-2.5 (-113)
+2.5 (-109)
O 59 (-110)
U 59 (-115)
Oct 25, 2025 12:00PM EDT
South Florida Bulls
Memphis Tigers
10/25/25 12PM
SFLA
MEMP
-200
+164
-4.5 (-115)
+4.5 (-105)
O 64.5 (-106)
U 64.5 (-114)
Oct 25, 2025 12:00PM EDT
UCLA Bruins
Indiana Hoosiers
10/25/25 12PM
UCLA
IND
+1400
-4000
+24.5 (-112)
-24.5 (-108)
O 53.5 (-110)
U 53.5 (-110)
Oct 25, 2025 12:00PM EDT
Northwestern Wildcats
Nebraska Cornhuskers
10/25/25 12PM
NWEST
NEB
+225
-280
+6.5 (+104)
-6.5 (-128)
O 43.5 (-105)
U 43.5 (-115)
Oct 25, 2025 12:00PM EDT
Ohio Bobcats
Eastern Michigan Eagles
10/25/25 12PM
OHIO
EMICH
-450
+340
-12.5 (-110)
+12.5 (-110)
O 59.5 (-110)
U 59.5 (-110)
Oct 25, 2025 12:00PM EDT
SMU Mustangs
Wake Forest Demon Deacons
10/25/25 12PM
SMU
WAKE
-166
+138
-3.5 (-105)
+3.5 (-115)
O 54.5 (-110)
U 54.5 (-110)
Oct 25, 2025 12:00PM EDT
Syracuse Orange
Georgia Tech Yellow Jackets
10/25/25 12PM
CUSE
GATECH
+610
-950
+17.5 (-115)
-17.5 (-105)
O 54.5 (-115)
U 54.5 (-105)
Oct 25, 2025 12:00PM EDT
App State Mountaineers
Old Dominion Monarchs
10/25/25 12PM
APPST
OLDDOM
 
-490
 
-13.5 (-110)
O 63.5 (-110)
U 63.5 (-110)
Oct 25, 2025 12:00PM EDT
Ole Miss Rebels
Oklahoma Sooners
10/25/25 12PM
OLEMISS
OKLA
+172
-210
+4.5 (-105)
-4.5 (-115)
O 53.5 (-110)
U 53.5 (-110)
Oct 25, 2025 12:00PM EDT
Kansas State Wildcats
Kansas Jayhawks
10/25/25 12PM
KSTATE
KANSAS
+122
-146
+2.5 (+100)
-2.5 (-122)
O 56.5 (-110)
U 56.5 (-110)
Oct 25, 2025 12:45PM EDT
Auburn Tigers
Arkansas Razorbacks
10/25/25 12:45PM
AUBURN
ARK
-106
-113
+1.5 (-115)
-1.5 (-105)
O 57.5 (-105)
U 57.5 (-115)
Oct 25, 2025 1:00PM EDT
Akron Zips
Buffalo Bulls
10/25/25 1PM
AKRON
BUFF
+260
-330
+9.5 (-115)
-9.5 (-105)
O 47.5 (-110)
U 47.5 (-110)
Oct 25, 2025 3:00PM EDT
UConn Huskies
Rice Owls
10/25/25 3PM
UCONN
RICE
-350
+275
-10.5 (-102)
+10.5 (-120)
O 48.5 (-110)
U 48.5 (-110)
Oct 25, 2025 3:00PM EDT
Utah State Aggies
New Mexico Lobos
10/25/25 3PM
UTAHST
NMEX
+115
-138
+2.5 (-105)
-2.5 (-115)
O 62.5 (-110)
U 62.5 (-110)
Oct 25, 2025 3:30PM EDT
Minnesota Golden Gophers
Iowa Hawkeyes
10/25/25 3:30PM
MINN
IOWA
+265
-335
+8.5 (-110)
-8.5 (-110)
O 38.5 (-112)
U 38.5 (-108)
Oct 25, 2025 3:30PM EDT
Alabama Crimson Tide
South Carolina Gamecocks
10/25/25 3:30PM
BAMA
SC
-465
+350
-11.5 (-110)
+11.5 (-110)
O 47.5 (-105)
U 47.5 (-115)
Oct 25, 2025 3:30PM EDT
BYU Cougars
Iowa State Cyclones
10/25/25 3:30PM
BYU
IOWAST
+116
-140
+2.5 (-105)
-2.5 (-115)
O 49.5 (-105)
U 49.5 (-115)
Oct 25, 2025 3:30PM EDT
Temple Owls
Tulsa Golden Hurricane
10/25/25 3:30PM
TEMPLE
TULSA
-210
+172
-5.5 (-114)
+5.5 (-106)
O 54.5 (-110)
U 54.5 (-110)
Oct 25, 2025 3:30PM EDT
Ball State Cardinals
Northern Illinois Huskies
10/25/25 3:30PM
BALLST
NILL
+176
-215
+5.5 (-110)
-5.5 (-110)
O 41.5 (-110)
U 41.5 (-110)
Oct 25, 2025 3:30PM EDT
Toledo Rockets
Washington State Cougars
10/25/25 3:30PM
TOLEDO
WASHST
-105
-115
+1.5 (-115)
-1.5 (-105)
O 47.5 (-110)
U 47.5 (-110)
Oct 25, 2025 3:30PM EDT
Florida Atlantic Owls
Navy Midshipmen
10/25/25 3:30PM
FAU
NAVY
+470
-670
+15.5 (-110)
-15.5 (-110)
O 62.5 (-115)
U 62.5 (-105)
Oct 25, 2025 3:30PM EDT
Illinois Fighting Illini
Washington Huskies
10/25/25 3:30PM
ILL
WASH
+146
-178
+4.5 (-115)
-4.5 (-105)
O 55.5 (-105)
U 55.5 (-115)
Oct 25, 2025 3:30PM EDT
Umass Minutemen
Central Michigan Chippewas
10/25/25 3:30PM
UMASS
CMICH
 
-800
 
-16.5 (-115)
O 46.5 (-110)
U 46.5 (-110)
Oct 25, 2025 3:30PM EDT
San Diego State Aztecs
Fresno State Bulldogs
10/25/25 3:30PM
SDGST
FRESNO
-152
+126
-3.5 (+102)
+3.5 (-124)
O 48.5 (-110)
U 48.5 (-110)
Oct 25, 2025 3:30PM EDT
Missouri Tigers
Vanderbilt Commodores
10/25/25 3:30PM
MIZZOU
VANDY
+115
-138
+2.5 (-106)
-2.5 (-114)
O 51.5 (-114)
U 51.5 (-106)
Oct 25, 2025 3:30PM EDT
NC State Wolfpack
Pittsburgh Panthers
10/25/25 3:30PM
NCST
PITT
+190
-235
+6.5 (-110)
-6.5 (-110)
O 57.5 (-105)
U 57.5 (-115)
Oct 25, 2025 3:30PM EDT
Western Michigan Broncos
Miami Ohio Redhawks
10/25/25 3:30PM
WMICH
MIAOH
+114
 
+2.5 (-110)
 
O 41.5 (-110)
U 41.5 (-110)
Oct 25, 2025 3:30PM EDT
UL Monroe Warhawks
USM Golden Eagles
10/25/25 3:30PM
MONROE
USM
+340
 
+11.5 (-105)
 
O 50.5 (-110)
U 50.5 (-110)
Oct 25, 2025 4:00PM EDT
Oklahoma State Cowboys
Texas Tech Red Raiders
10/25/25 4PM
OKLAST
TXTECH
+3500
-10000
+38.5 (-110)
-38.5 (-110)
O 56.5 (-115)
U 56.5 (-105)
Oct 25, 2025 4:00PM EDT
Baylor Bears
Cincinnati Bearcats
10/25/25 4PM
BAYLOR
CINCY
+152
-184
+4.5 (-115)
-4.5 (-105)
O 67.5 (-110)
U 67.5 (-110)
Oct 25, 2025 4:15PM EDT
Texas Longhorns
Mississippi State Bulldogs
10/25/25 4:15PM
TEXAS
MISSST
-285
+230
-7.5 (-105)
+7.5 (-115)
O 44.5 (-115)
U 44.5 (-105)
Oct 25, 2025 6:00PM EDT
TCU Horned Frogs
West Virginia Mountaineers
10/25/25 6PM
TCU
WVU
-600
+430
-14.5 (-110)
+14.5 (-110)
O 56.5 (-110)
U 56.5 (-110)
Oct 25, 2025 7:00PM EDT
Wisconsin Badgers
Oregon Ducks
10/25/25 7PM
WISC
OREG
 
 
+34.5 (-115)
-34.5 (-105)
O 44.5 (-114)
U 44.5 (-106)
Oct 25, 2025 7:00PM EDT
Louisiana Ragin Cajuns
Troy Trojans
10/25/25 7PM
UL
TROY
+290
-375
+9.5 (-105)
-9.5 (-115)
O 48.5 (-108)
U 48.5 (-112)
Oct 25, 2025 7:00PM EDT
Stanford Cardinal
Miami Hurricanes
10/25/25 7PM
STNFRD
MIAMI
+3500
-20000
+30.5 (-115)
-30.5 (-105)
O 45.5 (-104)
U 45.5 (-118)
Oct 25, 2025 7:00PM EDT
Georgia Southern Eagles
Arkansas State Red Wolves
10/25/25 7PM
GASO
ARKST
+105
-126
+2.5 (-115)
-2.5 (-105)
O 62.5 (-110)
U 62.5 (-110)
Oct 25, 2025 7:30PM EDT
Michigan Wolverines
Michigan State Spartans
10/25/25 7:30PM
MICH
MICHST
-690
+480
-13.5 (-120)
+13.5 (-102)
O 48.5 (-105)
U 48.5 (-115)
Oct 25, 2025 7:30PM EDT
Texas A&M Aggies
LSU Tigers
10/25/25 7:30PM
TEXAM
LSU
-140
+116
-2.5 (-115)
+2.5 (-105)
O 48.5 (-104)
U 48.5 (-118)
Oct 25, 2025 7:30PM EDT
Boston College Eagles
Louisville Cardinals
10/25/25 7:30PM
BC
LVILLE
+1400
-4000
+25.5 (-110)
-25.5 (-110)
O 55.5 (-104)
U 55.5 (-118)
Oct 25, 2025 7:30PM EDT
Colorado State Rams
Wyoming Cowboys
10/25/25 7:30PM
COLOST
WYO
+180
-220
+5.5 (-105)
-5.5 (-115)
O 46.5 (-110)
U 46.5 (-110)
Oct 25, 2025 7:45PM EDT
Tennessee Volunteers
Kentucky Wildcats
10/25/25 7:45PM
TENN
UK
-345
+265
-9.5 (-110)
+9.5 (-110)
O 53.5 (-118)
U 53.5 (-104)
Oct 25, 2025 8:00PM EDT
Houston Cougars
Arizona State Sun Devils
10/25/25 8PM
HOU
ARIZST
+245
-310
+7.5 (-110)
-7.5 (-110)
O 46.5 (-110)
U 46.5 (-110)
Oct 25, 2025 10:15PM EDT
Colorado Buffaloes
Utah Utes
10/25/25 10:15PM
COLO
UTAH
+385
-520
+13.5 (-108)
-13.5 (-112)
O 49.5 (-115)
U 49.5 (-105)

CFB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Indiana Hoosiers vs. Notre Dame Fighting Irish on December 20, 2024 at Notre Dame Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our CFB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
FSU@STNFRD STNFRD +18 56.6% 6 WIN
WASHST@UVA WASHST +17.5 58.8% 8 WIN
NEVADA@NMEX NEVADA +13.5 57.8% 7 WIN
TEXAS@UK ARCH MANNING UNDER 1.5 PASS TD 56.1% 6 WIN
ARMY@TULANE ARMY +10 55.3% 5 WIN
SJST@UTAHST SJST +4 54.4% 4 LOSS
LVILLE@MIAMI LVILLE +12.5 56.5% 6 WIN
LVILLE@MIAMI CJ DANIELS UNDER 4.5 RECEPTIONS 54.4 4 LOSS
DEL@JAXST DEL -2.5 57.6% 6 LOSS
UTEP@SAMST UTEP -2.5 53.9% 3 WIN
FIU@WKY FIU +10.5 54.6% 4 WIN
ARKST@SALA ARKST +7.5 54.5% 4 WIN
ARKST@SALA JAYLEN RAYNOR UNDER 40.5 LONGEST PASS COMP 53.3% 3 WIN
SJST@WYO SJST -120 59.8% 7 LOSS
UMASS@KENTST KENTST -135 60.2% 6 WIN
NOILL@EMICH EMICH +2.5 53.9% 3 WIN
BYU@ARIZ ARIZ +2.5 54.2% 3 LOSS
OKLA@TEXAS OKLA +2.5 54.7% 4 LOSS
NMEX@BOISE NMEX +16.5 56.4% 6 WIN
WAKE@OREGST WAKE -2.5 56.7% 6 WIN
ULMON@COASTAL ULMON -2.5 56.8% 6 LOSS
IOWA@WISC WISC +4 54.8% 4 LOSS
TOLEDO@BGREEN TOLEDO -10 56.3% 6 LOSS
SFLA@NOTEX SFLA +2.5 54.3% 4 WIN
FRESNO@COLOST RICHIE ANDERSON III LONGEST RECEPTION UNDER 16.5 54.4% 4 LOSS
JAXST@SAMST SAMST +7.5 55.3% 5 WIN
USM@GAS GAS +3.5 57.4% 7 WIN
LIB@UTEP UTEP +2 54.5% 4 LOSS
SALA@TROY SALA -118 55.2% 4 LOSS
TULSA@MEMP MEMP -20.5 53.8% 3 WIN
JMAD@GAST GAST +20.5 54.6% 4 WIN
WAKE@VATECH VATECH -5.5 56.6% 6 LOSS
UNLV@WYO WYO +4.5 55.5% 5 LOSS
PSU@UCLA PSU -24.5 56.3% 6 LOSS
TXSTSM@ARKST TXSTSM -13 56.7% 6 LOSS
UVA@LVILLE ISAAC BROWN OVER 70.5 RUSH YDS 56.6% 6 LOSS
WVU@BYU WVU +20.5 54.7% 4 WIN
SAMST@NMEXST SAMST -1.5 54.1% 3 LOSS
EMICH@CMICH CMICH -148 62.8% 7 WIN
SDGST@NOILL SDGST -118 55.7% 3 WIN
BAMA@GEORGIA GEORGIA -125 58.7% 7 LOSS
TENN@MISSST MISSST +7.5 54.3% 4 WIN
UK@SC SC -5.5 54.8% 4 WIN
WKY@MIZZST MIZZST +4.5 55.6% 6 LOSS
JAXST@USM USM -3.5 56.0% 5 WIN
NMEXST@NMEX NMEX -14.5 56.9% 6 WIN
ARIZ@IOWAST ROCCO BECHT UNDER 1.5 PASS TDS 55.5% 5 WIN
TCU@ARIZST JOSH HOOVER PASS YDS UNDER 287.5 53.4% 3 WIN
ARIZST@BAYLOR BAYLOR -130 58.4% 6 LOSS
WYO@COLO WYO +13.5 54.1% 3 LOSS
TULANE@OLEMISS MISS -11.5 54.3% 4 WIN