Panthers vs. Cardinals
Prediction, Odds & Props
Nov 23 | CFB AI Picks

Updated: 2024-11-16T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

On November 23, 2024, the Pittsburgh Panthers will face the Louisville Cardinals at L&N Federal Credit Union Stadium in Louisville, Kentucky. This ACC matchup is crucial for both teams as they vie for improved standings and potential bowl game invitations.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Nov 23, 2024

Start Time: 5:00 PM EST​

Venue: L&N Federal Credit Union Stadium​

Cardinals Record: (6-4)

Panthers Record: (7-3)

OPENING ODDS

PITT Moneyline: +225

LVILLE Moneyline: -280

PITT Spread: +7.5

LVILLE Spread: -7.5

Over/Under: 56.5

PITT
Betting Trends

  • The Pittsburgh Panthers have struggled against the spread (ATS) recently, covering in only 2 of their last 5 games. Their inconsistent offensive performances have contributed to difficulties in meeting betting expectations.

LVILLE
Betting Trends

  • The Louisville Cardinals have fared slightly better ATS, covering in 3 of their last 5 games. However, their performances have been erratic, particularly in close contests, affecting their reliability for bettors.

MATCHUP TRENDS

  • In their last five head-to-head matchups, the underdog has covered the spread four times, indicating a trend of closely contested games regardless of team rankings.

PITT vs. LVILLE
Best Prop Bet

  • Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.

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Pittsburgh vs Louisville Prediction & Odds:
Free CFB Betting Insights for 11/23/24

The upcoming clash between the Pittsburgh Panthers and the Louisville Cardinals on November 23, 2024, at L&N Federal Credit Union Stadium is pivotal for both programs. Pittsburgh enters the game with a 7-3 record, aiming to solidify their position in the ACC standings and secure a favorable bowl game invitation. Their season has been marked by a potent offense and a resilient defense, making them formidable contenders in the conference. Quarterback Christian Veilleux has been instrumental, amassing over 1,179 passing yards and 7 touchdowns, showcasing his ability to lead the offense effectively. The Panthers’ ground game, led by running back Rodney Hammond Jr., has also been impressive, contributing significantly to their balanced offensive attack. Defensively, Pittsburgh has been stout, allowing an average of just 27.3 points per game, with a secondary that has been particularly effective in limiting opponents’ passing yards.

On the other hand, Louisville enters the game with a 6-4 record, reflecting a season of ups and downs. The Cardinals have shown flashes of brilliance but have struggled with consistency, particularly in conference play. Quarterback Jack Plummer has had a mixed season, with moments of promise tempered by turnovers and missed opportunities. The rushing attack, traditionally a strength for Louisville, has been led by running back Jawhar Jordan, who has been a bright spot in their offense. Defensively, the Cardinals have faced challenges, especially in containing high-powered offenses, which could be a concern against Pittsburgh’s dynamic playmakers. Key factors in this matchup include turnover margin, third-down efficiency, and red-zone performance. Pittsburgh’s ability to protect the football and capitalize on scoring opportunities will be crucial, while Louisville will need to find ways to sustain drives and finish in the end zone. Given Pittsburgh’s current form and aspirations, they appear to have the upper hand, but Louisville’s potential to disrupt top teams adds an element of unpredictability to this contest.

Pittsburgh Panthers CFB Preview

The Pittsburgh Panthers have had a stellar season, entering this game with a 7-3 record. Head coach Pat Narduzzi has guided the team to a position where they are strong contenders for a favorable bowl game. Offensively, Pittsburgh has been prolific, averaging 20.2 points per game. Quarterback Christian Veilleux has been a revelation, throwing for over 1,179 yards and 7 touchdowns, demonstrating poise and precision in the pocket. His connection with wide receivers Bub Means and Konata Mumpfield has been particularly effective, stretching defenses and creating mismatches. The rushing attack has been equally formidable, with running back Rodney Hammond Jr. rushing for over 547 yards and 5 touchdowns. Hammond’s blend of speed and power has made him a constant threat, keeping defenses honest and opening up play-action opportunities. Defensively, the Panthers have been stout, allowing just 27.3 points per game. Their defense is anchored by a dominant front seven, with linebacker Shayne Simon leading the charge with 5 sacks and consistent pressure on opposing quarterbacks. Linebacker Donovan McMillon has been a tackling machine, recording over 104 tackles and showcasing his ability to disrupt both the run and pass games. The secondary, led by safety M.J. Devonshire, has been solid in limiting explosive plays and forcing turnovers with timely interceptions. This well-rounded defensive unit has been instrumental in keeping opponents’ scoring in check, particularly in high-stakes games. For Pittsburgh to secure a road win against Louisville, they must continue executing their balanced offensive strategy while maintaining discipline on both sides of the ball. Christian Veilleux needs to deliver an efficient passing performance, utilizing Bub Means and Konata Mumpfield to stretch the field and create mismatches. Rodney Hammond Jr. must establish the ground game early, controlling the tempo and opening up opportunities for play-action passes. Defensively, the Panthers need to contain Jawhar Jordan and pressure Jack Plummer, forcing the Cardinals into third-and-long situations where mistakes are more likely. Winning the turnover battle and converting red-zone opportunities will be critical for Pittsburgh as they aim to secure an important victory and solidify their standing in the ACC. With their combination of offensive firepower and defensive tenacity, the Panthers are well-positioned to overcome Louisville in a closely contested matchup.

On November 23, 2024, the Pittsburgh Panthers will face the Louisville Cardinals at L&N Federal Credit Union Stadium in Louisville, Kentucky. This ACC matchup is crucial for both teams as they vie for improved standings and potential bowl game invitations. Pittsburgh vs Louisville AI Prediction: Free CFB Betting Insights for Nov 23. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Louisville Cardinals CFB Preview

The Louisville Cardinals have experienced a roller-coaster season, entering this matchup with a 6-4 record. Under head coach Jeff Brohm, the team has showcased resilience but has been hampered by inconsistencies on both sides of the ball. Offensively, Louisville averages 30.7 points per game, with quarterback Jack Plummer leading the charge. Plummer has thrown for over 3,204 yards and 22 touchdowns but has also been prone to interceptions, which have stalled drives and shifted momentum in critical moments. The rushing attack, a cornerstone of Louisville’s offense, has been spearheaded by running back Jawhar Jordan, who has rushed for over 1,128 yards and 7 touchdowns. Jordan’s emergence has provided a spark, but the offensive line’s inconsistency has affected the ground game’s overall effectiveness. Defensively, the Cardinals have allowed an average of 21.3 points per game, struggling particularly against high-tempo offenses. The secondary has been a point of concern, giving up substantial yardage through the air, which could be problematic against Pittsburgh’s potent passing attack. Linebacker TJ Quinn has been a standout, leading the team in tackles and providing leadership on the field. However, the defense’s inability to generate consistent pressure on opposing quarterbacks has exposed vulnerabilities in coverage. For Louisville to compete effectively against Pittsburgh, they will need to play a disciplined game, minimizing turnovers and capitalizing on scoring opportunities. Establishing the run early with Jordan and utilizing play-action to open up passing lanes for Plummer will be essential strategies. Defensively, the Cardinals must find ways to disrupt Christian Veilleux’s rhythm and contain Rodney Hammond Jr. to prevent explosive plays. Special teams could also play a pivotal role, with field position and the kicking game potentially influencing the outcome. While Louisville faces an uphill battle against a top-ranked opponent, their capacity to rise to the occasion in high-stakes games cannot be underestimated.

Pittsburgh vs. Louisville Prop Picks (AI)

Remi is pouring through tons of stats on each line. In fact, anytime the Panthers and Cardinals play there’s always several intriguing observations to key in on. Not to mention games played at L&N Federal Credit Union Stadium in Nov can often follow normal, predictable patterns.
Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.

Pittsburgh vs. Louisville Prediction (AI)

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Remi, our AI sports genius, has been pouring over exorbitant amounts of data from every angle between the Panthers and Cardinals and using recursive machine learning and kick-ass AI to examine the data to a single cover probability.

Remi has been most focused on the trending factor emotional bettors tend to put on player performance factors between a Panthers team going up against a possibly tired Cardinals team. Trends look to say the true game analytics appear to reflect a slight lean against one Vegas line specifically.

Unlock this in-depth AI prediction and all of our CFB AI picks for FREE now.

Below is our current AI Pittsburgh vs Louisville picks, computer picks Panthers vs Cardinals, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
CFB 9/26 TCU@ARIZST UNLOCK THIS PICK 3 EXECUTIVE Locked EXECUTIVE
CFB 9/26 FSU@UVA UNLOCK THIS PICK 0 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full CFB schedule. 

Panthers Betting Trends

The Pittsburgh Panthers have struggled against the spread (ATS) recently, covering in only 2 of their last 5 games. Their inconsistent offensive performances have contributed to difficulties in meeting betting expectations.

Cardinals Betting Trends

The Louisville Cardinals have fared slightly better ATS, covering in 3 of their last 5 games. However, their performances have been erratic, particularly in close contests, affecting their reliability for bettors.

Panthers vs. Cardinals Matchup Trends

In their last five head-to-head matchups, the underdog has covered the spread four times, indicating a trend of closely contested games regardless of team rankings.

Pittsburgh vs. Louisville Game Info

Pittsburgh vs Louisville starts on November 23, 2024 at 5:00 PM EST.

Venue: L&N Federal Credit Union Stadium.

Spread: Louisville -7.5
Moneyline: Pittsburgh +225, Louisville -280
Over/Under: 56.5

Pittsburgh: (7-3)  |  Louisville: (6-4)

Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.. Prices move—always shop for the best number.

In their last five head-to-head matchups, the underdog has covered the spread four times, indicating a trend of closely contested games regardless of team rankings.

PITT trend: The Pittsburgh Panthers have struggled against the spread (ATS) recently, covering in only 2 of their last 5 games. Their inconsistent offensive performances have contributed to difficulties in meeting betting expectations.

LVILLE trend: The Louisville Cardinals have fared slightly better ATS, covering in 3 of their last 5 games. However, their performances have been erratic, particularly in close contests, affecting their reliability for bettors.

See our latest CFB picks and odds pages for 2024 to compare prices before you bet.

Pittsburgh vs. Louisville Odds

AI algorithm Remi is pouring through loads of data on each team. In fact, anytime the Pittsburgh vs Louisville trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme travel distance rarely follow normal, predictable patterns.

Pittsburgh vs Louisville Opening Odds

PITT Moneyline: +225
LVILLE Moneyline: -280
PITT Spread: +7.5
LVILLE Spread: -7.5
Over/Under: 56.5

Pittsburgh vs Louisville Live Odds

Games PTS ML SPR O/U
Sep 27, 2025 12:00PM EDT
Bowling Green Falcons
Ohio Bobcats
9/27/25 12PM
BGREEN
OHIO
+245
-310
+7.5 (-110)
-7.5 (-110)
O 50.5 (-110)
U 50.5 (-110)
Sep 27, 2025 12:00PM EDT
South Alabama Jaguars
North Texas Mean Green
9/27/25 12PM
SBAMA
NOTEX
+355
-475
+12.5 (-110)
-12.5 (-110)
O 63.5 (-115)
U 63.5 (-105)
Sep 27, 2025 12:00PM EDT
UCF Knights
Kansas State Wildcats
9/27/25 12PM
UCF
KSTATE
+170
-205
+5.5 (-115)
-5.5 (-105)
O 48.5 (-110)
U 48.5 (-110)
Sep 27, 2025 12:00PM EDT
Georgia Tech Yellow Jackets
Wake Forest Demon Deacons
9/27/25 12PM
GATECH
WAKE
-575
+420
-13.5 (-115)
+13.5 (-105)
O 52.5 (-105)
U 52.5 (-115)
Sep 27, 2025 12:00PM EDT
USC Trojans
Illinois Fighting Illini
9/27/25 12PM
USC
ILL
-240
+203
-6.5 (-115)
+6.5 (-105)
O 61 (-110)
U 61 (-110)
Sep 27, 2025 12:00PM EDT
Notre Dame Fighting Irish
Arkansas Razorbacks
9/27/25 12PM
ND
ARK
-190
+155
-4.5 (-105)
+4.5 (-115)
O 63.5 (-110)
U 63.5 (-110)
Sep 27, 2025 12:00PM EDT
Cincinnati Bearcats
Kansas Jayhawks
9/27/25 12PM
CINCY
KANSAS
+165
-200
+4.5 (-110)
-4.5 (-110)
O 56.5 (-110)
U 56.5 (-110)
Sep 27, 2025 12:00PM EDT
Louisville Cardinals
Pittsburgh Panthers
9/27/25 12PM
LVILLE
PITT
-175
+145
-3.5 (-115)
+3.5 (-105)
O 56 (-110)
U 56 (-110)
Sep 27, 2025 12:00PM EDT
Rutgers Scarlet Knights
Minnesota Golden Gophers
9/27/25 12PM
RUT
MINN
+170
-205
+5 (-110)
-5 (-110)
O 51 (-110)
U 51 (-110)
Sep 27, 2025 12:00PM EDT
Duke Blue Devils
Syracuse Orange
9/27/25 12PM
DUKE
CUSE
-190
+155
-4.5 (-110)
+4.5 (-110)
O 59.5 (-105)
U 59.5 (-115)
Sep 27, 2025 12:45PM EDT
Utah State Aggies
Vanderbilt Commodores
9/27/25 12:45PM
UTAHST
VANDY
+1100
-2000
+23.5 (-110)
-23.5 (-110)
O 58 (-110)
U 58 (-110)
Sep 27, 2025 1:00PM EDT
Eastern Michigan Eagles
Central Michigan Chippewas
9/27/25 1PM
EMICH
CMICH
+130
-155
+3.5 (-120)
-3.5 (+100)
O 54.5 (-115)
U 54.5 (-105)
Sep 27, 2025 1:30PM EDT
Georgia Southern Eagles
James Madison Dukes
9/27/25 1:30PM
GASO
JMAD
+490
-700
+15.5 (-110)
-15.5 (-110)
O 54.5 (-110)
U 54.5 (-110)
Sep 27, 2025 3:00PM EDT
Arkansas State Red Wolves
UL Monroe Warhawks
9/27/25 3PM
ARKST
MONROE
+100
-120
+1.5 (-110)
-1.5 (-110)
O 55 (-110)
U 55 (-110)
Sep 27, 2025 3:30PM EDT
San Diego State Aztecs
Northern Illinois Huskies
9/27/25 3:30PM
SDGST
NILL
-130
+110
-2 (-110)
+2 (-110)
O 43 (-110)
U 43 (-110)
Sep 27, 2025 3:30PM EDT
UCLA Bruins
Northwestern Wildcats
9/27/25 3:30PM
UCLA
NWEST
+183
-215
+6 (-110)
-6 (-110)
O 46 (-110)
U 46 (-110)
Sep 27, 2025 3:30PM EDT
Akron Zips
Toledo Rockets
9/27/25 3:30PM
AKRON
TOLEDO
+900
-1500
+20.5 (-105)
-20.5 (-115)
O 49 (-110)
U 49 (-110)
Sep 27, 2025 3:30PM EDT
Ohio State Buckeyes
Washington Huskies
9/27/25 3:30PM
OHIOST
WASH
-325
+265
-8.5 (-110)
+8.5 (-110)
O 53 (-110)
U 53 (-110)
Sep 27, 2025 3:30PM EDT
Auburn Tigers
Texas A&M Aggies
9/27/25 3:30PM
AUBURN
TEXAM
+205
-255
+7 (-115)
-7 (-105)
O 52.5 (-110)
U 52.5 (-110)
Sep 27, 2025 3:30PM EDT
Baylor Bears
Oklahoma State Cowboys
9/27/25 3:30PM
BAYLOR
OKLAST
-1400
+825
-21 (-110)
+21 (-110)
O 58.5 (-110)
U 58.5 (-110)
Sep 27, 2025 3:30PM EDT
Lindenwood Lions
Miami Ohio Redhawks
9/27/25 3:30PM
LINDEN
MIAOH
+850
 
+20.5 (-105)
 
O 49.5 (-110)
U 49.5 (-110)
Sep 27, 2025 3:30PM EDT
Indiana Hoosiers
Iowa Hawkeyes
9/27/25 3:30PM
IND
IOWA
-325
+265
-8.5 (-110)
+8.5 (-110)
O 47.5 (-110)
U 47.5 (-110)
Sep 27, 2025 3:30PM EDT
Rice Owls
Navy Midshipmen
9/27/25 3:30PM
RICE
NAVY
+430
-600
+14 (-110)
-14 (-110)
O 45 (-110)
U 45 (-110)
Sep 27, 2025 3:30PM EDT
Utah Utes
West Virginia Mountaineers
9/27/25 3:30PM
UTAH
WVU
-475
+355
-12.5 (-110)
+12.5 (-110)
O 47.5 (-110)
U 47.5 (-110)
Sep 27, 2025 3:30PM EDT
UConn Huskies
Buffalo Bulls
9/27/25 3:30PM
UCONN
BUFF
-165
+142
-3.5 (-110)
+3.5 (-110)
O 50.5 (-110)
U 50.5 (-110)
Sep 27, 2025 3:30PM EDT
California Golden Bears
Boston College Eagles
9/27/25 3:30PM
CAL
BC
+185
-225
+6 (-110)
-6 (-110)
O 53.5 (-110)
U 53.5 (-110)
Sep 27, 2025 3:30PM EDT
LSU Tigers
Ole Miss Rebels
9/27/25 3:30PM
LSU
OLEMISS
+100
-120
+2 (-110)
-2 (-110)
O 57.5 (-110)
U 57.5 (-110)
Sep 27, 2025 4:00PM EDT
New Mexico State Aggies
New Mexico Lobos
9/27/25 4PM
NMEXST
NMEX
+475
-650
+16 (-110)
-16 (-110)
O 53.5 (-110)
U 53.5 (-110)
Sep 27, 2025 4:00PM EDT
Tulane Green Wave
Tulsa Golden Hurricane
9/27/25 4PM
TULANE
TULSA
-700
+500
-15.5 (-110)
+15.5 (-110)
O 52 (-110)
U 52 (-110)
Sep 27, 2025 4:10PM EDT
Hawaii Rainbow Warriors
Air Force Falcons
9/27/25 4:10PM
HAWAII
AF
+205
-245
+6.5 (-105)
-6.5 (-115)
O 52.5 (-110)
U 52.5 (-110)
Sep 27, 2025 4:15PM EDT
Tennessee Volunteers
Mississippi State Bulldogs
9/27/25 4:15PM
TENN
MISSST
-275
+230
-7 (-115)
+7 (-105)
O 62.5 (-110)
U 62.5 (-110)
Sep 27, 2025 6:00PM EDT
MTSU Blue Raiders
Kennesaw State Owls
9/27/25 6PM
MTSU
KENSAW
 
-260
 
-7 (-110)
O 53.5 (-110)
U 53.5 (-110)
Sep 27, 2025 6:00PM EDT
Liberty Flames
Old Dominion Monarchs
9/27/25 6PM
LIB
OLDDOM
+465
-625
+14.5 (-110)
-14.5 (-110)
O 54 (-110)
U 54 (-110)
Sep 27, 2025 6:30PM EDT
Rhode Island Rams
Western Michigan Broncos
9/27/25 6:30PM
RI
WMICH
+230
-285
+7.5 (-110)
-7.5 (-110)
O 43.5 (-110)
U 43.5 (-110)
Sep 27, 2025 7:00PM EDT
Memphis Tigers
Florida Atlantic Owls
9/27/25 7PM
MEMP
FAU
-540
+417
-14 (-110)
+14 (-110)
O 62 (-110)
U 62 (-110)
Sep 27, 2025 7:00PM EDT
Virginia Tech Hokies
NC State Wolfpack
9/27/25 7PM
VATECH
NCST
+275
-340
+9.5 (-110)
-9.5 (-110)
O 57.5 (-110)
U 57.5 (-110)
Sep 27, 2025 7:00PM EDT
Western Kentucky Hilltoppers
Missouri State Bears
9/27/25 7PM
WKY
MIZZST
-180
+155
-3.5 (-110)
+3.5 (-110)
O 60 (-110)
U 60 (-110)
Sep 27, 2025 7:00PM EDT
Arizona Wildcats
Iowa State Cyclones
9/27/25 7PM
ARIZ
IOWAST
+167
-195
+5 (-110)
-5 (-110)
O 48.5 (-110)
U 48.5 (-110)
Sep 27, 2025 7:00PM EDT
Jacksonville State Gamecocks
USM Golden Eagles
9/27/25 7PM
JAXST
USM
+146
 
+3.5 (-110)
 
O 56 (-110)
U 56 (-110)
Sep 27, 2025 7:30PM EDT
Oregon Ducks
Penn State Nittany Lions
9/27/25 7:30PM
OREG
PSU
+146
-170
+3.5 (-105)
-3.5 (-115)
O 53 (-110)
U 53 (-110)
Sep 27, 2025 7:30PM EDT
App State Mountaineers
Boise State Broncos
9/27/25 7:30PM
APPST
BOISE
 
-750
 
-16.5 (-110)
O 59 (-110)
U 59 (-110)
Sep 27, 2025 7:30PM EDT
Alabama Crimson Tide
Georgia Bulldogs
9/27/25 7:30PM
BAMA
UGA
+115
-135
+2.5 (-110)
-2.5 (-110)
O 53.5 (-110)
U 53.5 (-110)
Sep 27, 2025 7:30PM EDT
Umass Minutemen
Missouri Tigers
9/27/25 7:30PM
UMASS
MIZZOU
 
 
 
-44.5 (-110)
O 56.5 (-110)
U 56.5 (-110)
Sep 27, 2025 7:30PM EDT
San Jose State Spartans
Stanford Cardinal
9/27/25 7:30PM
SJST
STNFRD
+129
-150
+3 (-110)
-3 (-110)
O 49.5 (-110)
U 49.5 (-110)
Sep 27, 2025 7:30PM EDT
Washington State Cougars
Colorado State Rams
9/27/25 7:30PM
WASHST
COLOST
+175
-205
+5.5 (-110)
-5.5 (-110)
O 49.5 (-110)
U 49.5 (-110)
Sep 27, 2025 7:45PM EDT
Kentucky Wildcats
South Carolina Gamecocks
9/27/25 7:45PM
UK
SC
+180
-210
+5.5 (-110)
-5.5 (-110)
O 47.5 (-110)
U 47.5 (-110)
Sep 27, 2025 8:00PM EDT
Marshall Thundering Herd
Louisiana Ragin Cajuns
9/27/25 8PM
MARSH
UL
-125
+105
-2 (-110)
+2 (-110)
O 48 (-115)
U 48 (-105)
Sep 27, 2025 9:00PM EDT
Louisiana Tech Bulldogs
UTEP Miners
9/27/25 9PM
LATECH
UTEP
-175
+150
-3.5 (-110)
+3.5 (-110)
O 48 (-110)
U 48 (-110)
Sep 27, 2025 10:15PM EDT
BYU Cougars
Colorado Buffaloes
9/27/25 10:15PM
BYU
COLO
-235
+200
-6.5 (-110)
+6.5 (-110)
O 49.5 (-110)
U 49.5 (-110)
Oct 4, 2025 12:00PM EDT
Minnesota Golden Gophers
Ohio State Buckeyes
10/4/25 12PM
MINN
OHIOST
 
 
+21 (-110)
-21 (-110)
Oct 4, 2025 12:00PM EDT
Kentucky Wildcats
Georgia Bulldogs
10/4/25 12PM
UK
UGA
 
 
+20.5 (-110)
-20.5 (-110)
Oct 4, 2025 12:00PM EDT
Clemson Tigers
North Carolina Tar Heels
10/4/25 12PM
CLEM
UNC
-550
+400
-12.5 (-115)
+12.5 (-105)
O 48.5 (-110)
U 48.5 (-110)
Oct 4, 2025 12:00PM EDT
Wisconsin Badgers
Michigan Wolverines
10/4/25 12PM
WISC
MICH
+580
-880
+15.5 (-105)
-15.5 (-115)
O 41.5 (-105)
U 41.5 (-115)
Oct 4, 2025 1:00PM EDT
UTSA Roadrunners
Temple Owls
10/4/25 1PM
UTSA
TEMPLE
-210
+172
-5.5 (-115)
+5.5 (-105)
O 56.5 (-110)
U 56.5 (-110)
Oct 4, 2025 3:30PM EDT
Vanderbilt Commodores
Alabama Crimson Tide
10/4/25 3:30PM
VANDY
BAMA
+360
-480
+11.5 (-102)
-11.5 (-120)
O 51.5 (-110)
U 51.5 (-110)
Oct 4, 2025 3:30PM EDT
Washington Huskies
Maryland Terrapins
10/4/25 3:30PM
WASH
MD
 
 
-7 (-110)
+7 (-110)
Oct 4, 2025 3:30PM EDT
Boise State Broncos
Notre Dame Fighting Irish
10/4/25 3:30PM
BOISE
ND
+365
-490
+13.5 (-105)
-13.5 (-115)
O 61.5 (-110)
U 61.5 (-110)
Oct 4, 2025 3:30PM EDT
Texas Longhorns
Florida Gators
10/4/25 3:30PM
TEXAS
FLA
-300
+240
-7.5 (-110)
+7.5 (-110)
O 46.5 (-110)
U 46.5 (-110)
Oct 4, 2025 4:00PM EDT
Kent State Golden Flashes
Oklahoma Sooners
10/4/25 4PM
KENT
OKLA
 
 
+45.5 (-110)
-45.5 (-110)
O 52.5 (-115)
U 52.5 (-105)
Oct 4, 2025 4:00PM EDT
Michigan State Spartans
Nebraska Cornhuskers
10/4/25 4PM
MICHST
NEB
+360
-480
+12.5 (-105)
-12.5 (-115)
O 53.5 (-110)
U 53.5 (-110)

CFB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Pittsburgh Panthers vs. Louisville Cardinals on November 23, 2024 at L&N Federal Credit Union Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our CFB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
TULANE@OLEMISS MISS -11.5 54.3% 4 WIN
UNC@UCF UCF -6.5 54.4% 4 WIN
ARKST@KENSAW KENSAW +4.5 54.5% 4 WIN
ILL@IND IND -6 53.2% 3 WIN
SELOU@LSU LSU -47.5 55.3% 5 LOSS
TNMART@MIZZST MIZZST -14.5 56.2% 6 WIN
FRESNO@HAWAII HAWAII +3 56.6% 6 WIN
MRSHL@MTSU MTSU +2.5 56.8% 6 LOSS
MICH@NEB NEB +1.5 57.3% 7 LOSS
WASH@WASHST DENZEL BOSTON UNDER 69.5 RECV YDS 56.2% 6 LOSS
IOWA@RUT ANTWAN RAYMOND OVER 0.5 TOUCHDOWNS 54.4% 4 WIN
GEORGIA@TENN UNDER 50.5 55.5% 6 LOSS
ARK@OLEMISS MISS -225 72.0% 9 WIN
DUKE@TULANE TULANE -120 56.5% 4 WIN
ARK@OLEMISS MISS -6.5 53.9% 3 LOSS
AKRON@UAB UAB -11 54.7% 4 LOSS
UCONN@DEL DEL +9.5 55.0% 5 WIN
APLST@USM USM +4 55.3% 6 WIN
MERIMK@KENSAW KENSAW -13.5 56.2% 7 WIN
UMASS@IOWA IOWA -34.5 56.4% 7 WIN
UMASS@IOWA JAZIUN PATTERSON UNDER 0.5 RUSH TDS 54.8% 4 WIN
NMEX@UCLA NICO IAMALEAVA UNDER 31.5 PASS ATT 53.4% 3 LOSS
KSTATE@ARIZ ARIZ +1.5 56.1% 6 WIN
BC@MICHST NICK MARSH OVER 47.5 RCV YDS 53.6% 3 WIN
ARIZST@MISSST MISSST +7 54.2% 4 WIN
TULSA@NMEXST NMEXST +3.5 56.9% 6 WIN
UCLA@UNLV OVER 54.5 56.2% 6 LOSS
FRESNO@OREGST FRESNO +1.5 54.7% 4 WIN
VANDY@VATECH VANDY +2.5 55.8% 5 WIN
JMAD@LVILLE LVILLE -14.5 54.0% 3 LOSS
TCU@UNC JOSEPH MANJACK OVER 37.5 RECV YDS 53.8% 3 LOSS
ND@MIAMI MIAMI +3 55.2% 6 WIN
MISSST@USM USM +14.5 56.0% 6 LOSS
UTAH@UCLA UCLA +5.5 56.2% 6 LOSS
CAL@OREGST OREGST +1.5 55.1% 5 LOSS
FAU@MD MD -13.5 55.2% 5 WIN
GAS@FRESNO FRESNO +2 55.2% 5 WIN
TOLEDO@UK UK -9.5 56.2% 6 LOSS
AUSTPEAY@MTSU PEAY +12.5 56.2% 6 WIN
LSU@CLEM GARRETT NUSSMEIER OVER 23.5 PASS COMP 54.1% 3 WIN
WMICH@MICHST WMICH +21.5 56.2% 6 WIN
ND@OHIOST WILL HOWARD INTERCEPTIONS OVER 0.5 54.80% 4 LOSS
OHIOST@TEXAS WILL HOWARD PASS + RUSH YDS UNDER 262.5 54.70% 4 LOSS
GEORGIA@TEXAS TEXAS -144 54.40% 4 LOSS
AUBURN@BAMA PAYTON THORNE PASS TDS - UNDER 1.5 53.20% 3 WIN
PURDUE@IND IND -28.5 53.90% 3 WIN
FRESNO@UCLA T.J. HARDEN LONGEST RUSH OVER 17.5 YDS 54.50% 4 LOSS
TENN@VANDY VANDY +10.5 54.90% 4 LOSS
WVU@TXTECH TXTECH -2.5 54.60% 4 WIN
SC@CLEM CLEM -130 58.70% 4 LOSS
TCU@CINCY TCU -3 54.20% 4 WIN