Boilermakers vs. Spartans
Prediction, Odds & Props
Nov 22 | CFB AI Picks

Updated: 2024-11-15T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

On November 22, 2024, the Purdue Boilermakers will face the Michigan State Spartans at Spartan Stadium in East Lansing, Michigan. Both teams are looking to close their seasons on a positive note, with Purdue trying to snap a long losing streak and Michigan State aiming to solidify their bowl eligibility hopes.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Nov 22, 2024

Start Time: 9:00 PM EST​

Venue: Spartan Stadium​

Spartans Record: (4-6)

Boilermakers Record: (1-9)

OPENING ODDS

PURDUE Moneyline: +400

MICHST Moneyline: -549

PURDUE Spread: +14.5

MICHST Spread: -14.5

Over/Under: 48.5

PURDUE
Betting Trends

  • Purdue has struggled against the spread (ATS) this season, with a disappointing 2-7-0 record, covering only 22.2% of their games.

MICHST
Betting Trends

  • Michigan State has fared slightly better ATS, holding a 3-5-1 record, covering 37.5% of their games.

MATCHUP TRENDS

  • Michigan State has dominated this matchup at home, winning the last five meetings against Purdue at Spartan Stadium, highlighting their historical edge in East Lansing.

PURDUE vs. MICHST
Best Prop Bet

  • Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.

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Purdue vs Michigan State Prediction & Odds:
Free CFB Betting Insights for 11/22/24

The Purdue Boilermakers and Michigan State Spartans meet on November 22, 2024, in a Big Ten clash at Spartan Stadium. Purdue enters the matchup with a 1-8 record, desperate for a win to salvage an otherwise dismal season, while Michigan State sits at 4-5, seeking a victory to keep their postseason dreams alive. With both teams facing offensive and defensive challenges, the game’s outcome will likely hinge on execution and limiting mistakes. Offensively, Purdue has struggled mightily this season, averaging just 17.5 points per game. Quarterback Brady Allen has been inconsistent, throwing for 1,892 yards with 12 touchdowns and 10 interceptions. While Allen has shown flashes of potential, his decision-making has frequently hindered the team’s progress. The Boilermakers’ ground game has also been ineffective, averaging only 95.7 rushing yards per game. Running back Devin Mockobee leads the team with 432 yards on the ground but has faced difficulties running behind an offensive line that has been inconsistent in both pass protection and run blocking. Purdue’s receiving corps, led by TJ Sheffield and Deion Burks, has been a relative bright spot, combining for over 1,200 receiving yards and 8 touchdowns. However, the lack of a balanced offensive attack has made it difficult for the Boilermakers to sustain drives and generate scoring opportunities. Michigan State’s offense, on the other hand, has been more reliable, averaging 24.8 points per game. Quarterback Katin Houser has been a key contributor, throwing for 2,145 yards with 18 touchdowns and 8 interceptions. Houser has benefited from a solid offensive line and a complementary rushing attack led by Jalen Berger, who has accumulated 678 yards and 6 touchdowns this season.

Michigan State’s balanced approach, with an average of 245 passing yards and 140 rushing yards per game, has kept opposing defenses guessing. The Spartans’ ability to sustain drives and control the clock has been a critical factor in their four wins this season. Defensively, Purdue has struggled to stop opponents, allowing 31.2 points per game. Their run defense has been a major weakness, conceding 210.5 rushing yards per game, while the secondary has given up 220.8 passing yards per game. Linebacker Kydran Jenkins has been a standout, leading the team with 75 tackles and 4 sacks, but the defense has lacked depth and consistency. Conversely, Michigan State’s defense has been more effective, allowing 26.5 points per game. The Spartans’ run defense has been solid, holding opponents to 130.7 rushing yards per game, but their pass defense has shown vulnerabilities, surrendering 245.3 passing yards per game. Defensive end Simeon Barrow and linebacker Cal Haladay have anchored the unit, with Barrow contributing 6 sacks and Haladay leading the team with 82 tackles. With Michigan State playing at home and boasting a more balanced offense and a slightly better defense, they are the clear favorites. Purdue’s best chance lies in limiting turnovers and finding ways to exploit Michigan State’s secondary, but their struggles on both sides of the ball make an upset unlikely.

Purdue Boilermakers CFB Preview

The Michigan State Spartans enter their matchup against Purdue with a 4-5 record under head coach Mel Tucker. The Spartans have shown flashes of potential on both sides of the ball this season, and a win against Purdue would bring them closer to bowl eligibility. Offensively, Michigan State has been effective, averaging 24.8 points per game. Quarterback Katin Houser has been a steady presence, throwing for 2,145 yards with 18 touchdowns and 8 interceptions. Houser’s ability to distribute the ball has been key to the Spartans’ success, with wide receivers Montorie Foster Jr. and Tre Mosley combining for over 1,200 receiving yards and 10 touchdowns. The running game has also been productive, led by Jalen Berger, who has rushed for 678 yards and 6 touchdowns. Michigan State’s offensive line has provided solid protection for Houser, allowing the offense to maintain a balance between the pass and the run. This balance has been critical in sustaining drives and keeping opposing defenses on their heels. Defensively, the Spartans have been solid, allowing 26.5 points per game. The run defense has been a strength, conceding just 130.7 yards per game, thanks to the efforts of defensive linemen Simeon Barrow and linebackers Cal Haladay and Jacoby Windmon. Barrow leads the team with 6 sacks, consistently pressuring opposing quarterbacks, while Haladay has been the team’s top tackler with 82 stops on the season. However, the pass defense has shown vulnerabilities, giving up 245.3 passing yards per game. Despite this, Michigan State’s ability to generate pressure and disrupt offensive rhythm has kept their defense competitive. To secure a win against Purdue, Michigan State will need to exploit the Boilermakers’ defensive weaknesses, particularly their inability to stop the run. Establishing the ground game early with Berger will open up opportunities for Houser to take advantage of Purdue’s vulnerable secondary. Defensively, the Spartans must focus on containing Purdue quarterback Brady Allen and limiting big plays in the passing game. Given their balanced offense, home-field advantage, and more reliable defense, Michigan State is well-positioned to come out on top in this matchup.

On November 22, 2024, the Purdue Boilermakers will face the Michigan State Spartans at Spartan Stadium in East Lansing, Michigan. Both teams are looking to close their seasons on a positive note, with Purdue trying to snap a long losing streak and Michigan State aiming to solidify their bowl eligibility hopes. Purdue vs Michigan State AI Prediction: Free CFB Betting Insights for Nov 22. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Michigan State Spartans CFB Preview

The Purdue Boilermakers have endured a difficult 2024 season, entering the matchup against Michigan State with a 1-8 record under head coach Ryan Walters. The team has faced challenges across the board, particularly on offense, where they have struggled to consistently produce points and sustain drives. Offensively, Purdue has averaged just 17.5 points per game, one of the lowest marks in the Big Ten. Quarterback Brady Allen has shown moments of potential but has struggled with turnovers, throwing for 1,892 yards with 12 touchdowns and 10 interceptions. Allen’s inconsistency has hindered the team’s ability to capitalize on scoring opportunities. The rushing attack has been equally disappointing, averaging only 95.7 yards per game. Running back Devin Mockobee leads the team with 432 rushing yards but has faced difficulties finding running lanes due to inconsistent blocking from the offensive line. Purdue’s receiving corps has been a rare bright spot, with TJ Sheffield and Deion Burks combining for over 1,200 receiving yards and 8 touchdowns. However, the lack of balance between the passing and rushing attacks has made the Boilermakers’ offense predictable and easier for opposing defenses to stop. Defensively, Purdue has struggled to contain opponents, allowing 31.2 points per game. The run defense has been a significant weakness, giving up 210.5 rushing yards per game, ranking among the worst in the Big Ten. The pass defense has been marginally better, allowing 220.8 passing yards per game, but the lack of a consistent pass rush has left the secondary exposed. Linebacker Kydran Jenkins has been a bright spot, leading the team with 75 tackles and 4 sacks, but the defense as a whole has lacked playmakers capable of changing the game. Missed tackles, poor coverage, and an inability to generate turnovers have compounded Purdue’s defensive struggles. For Purdue to compete against Michigan State, they will need a near-flawless performance from their offense, particularly quarterback Brady Allen, who must limit turnovers and capitalize on scoring opportunities. Defensively, the Boilermakers will need to find a way to slow down Michigan State’s balanced attack, especially running back Jalen Berger, who has been effective on the ground. While an upset is not impossible, Purdue’s struggles on both sides of the ball make their path to victory narrow.

Purdue vs. Michigan State Prop Picks (AI)

AI algorithm Remi is pouring through tons of data on each team. In fact, anytime the Boilermakers and Spartans play there’s always several intriguing trends to key in on. Not to mention games played at Spartan Stadium in Nov seemingly never follow normal, predictable betting trends.
Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.

Purdue vs. Michigan State Prediction (AI)

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Remi, our AI sports genius, has been pouring over millions of data from every angle between the Boilermakers and Spartans and using recursive machine learning and cutting-edge AI to examine the data to a single cover probability.

The Algorithm has been most keyed in on the trending weight emotional bettors tend to put on Michigan State’s strength factors between a Boilermakers team going up against a possibly deflated Spartans team. We’ve found the true game analytics appear to reflect a moderate lean against one Vegas line specifically.

Unlock this in-depth AI prediction and all of our CFB AI picks for FREE now.

Below is our current AI Purdue vs Michigan State picks, computer picks Boilermakers vs Spartans, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
CFB 9/26 TCU@ARIZST UNLOCK THIS PICK 3 EXECUTIVE Locked EXECUTIVE
CFB 9/26 FSU@UVA UNLOCK THIS PICK 0 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full CFB schedule. 

Boilermakers Betting Trends

Purdue has struggled against the spread (ATS) this season, with a disappointing 2-7-0 record, covering only 22.2% of their games.

Spartans Betting Trends

Michigan State has fared slightly better ATS, holding a 3-5-1 record, covering 37.5% of their games.

Boilermakers vs. Spartans Matchup Trends

Michigan State has dominated this matchup at home, winning the last five meetings against Purdue at Spartan Stadium, highlighting their historical edge in East Lansing.

Purdue vs. Michigan State Game Info

Purdue vs Michigan State starts on November 22, 2024 at 9:00 PM EST.

Spread: Michigan State -14.5
Moneyline: Purdue +400, Michigan State -549
Over/Under: 48.5

Purdue: (1-9)  |  Michigan State: (4-6)

Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.. Prices move—always shop for the best number.

Michigan State has dominated this matchup at home, winning the last five meetings against Purdue at Spartan Stadium, highlighting their historical edge in East Lansing.

PURDUE trend: Purdue has struggled against the spread (ATS) this season, with a disappointing 2-7-0 record, covering only 22.2% of their games.

MICHST trend: Michigan State has fared slightly better ATS, holding a 3-5-1 record, covering 37.5% of their games.

See our latest CFB picks and odds pages for 2024 to compare prices before you bet.

Purdue vs. Michigan State Odds

Remi is pouring through tons of data points on each team. In fact, anytime the Purdue vs Michigan State trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme temps seemingly never follow normal, predictable betting trends.

Purdue vs Michigan State Opening Odds

PURDUE Moneyline: +400
MICHST Moneyline: -549
PURDUE Spread: +14.5
MICHST Spread: -14.5
Over/Under: 48.5

Purdue vs Michigan State Live Odds

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Utah State Aggies
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9/27/25 12:45PM
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Eastern Michigan Eagles
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9/27/25 1PM
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-155
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9/27/25 1:30PM
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Arkansas State Red Wolves
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9/27/25 3PM
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+100
-120
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+105
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Auburn Tigers
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+180
-240
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+980
 
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O 54 (-110)
U 54 (-110)
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U 57 (-112)
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U 53.5 (-110)
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U 52.5 (-110)
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O 63 (-110)
U 63 (-110)
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U 53 (-109)
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U 59 (-110)
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+112
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U 49 (-110)
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O 47.5 (-110)
U 47.5 (-110)
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-130
+110
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+2 (-110)
O 48 (-115)
U 48 (-105)
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Louisiana Tech Bulldogs
UTEP Miners
9/27/25 9PM
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UTEP
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+150
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O 48 (-110)
U 48 (-110)
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BYU Cougars
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-240
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O 49.5 (-110)
U 49.5 (-110)
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Minnesota Golden Gophers
Ohio State Buckeyes
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MINN
OHIOST
 
 
+21 (-110)
-21 (-110)
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Kentucky Wildcats
Georgia Bulldogs
10/4/25 12PM
UK
UGA
 
 
+20.5 (-110)
-20.5 (-110)
Oct 4, 2025 12:00PM EDT
Clemson Tigers
North Carolina Tar Heels
10/4/25 12PM
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-550
+400
-12.5 (-115)
+12.5 (-105)
O 48.5 (-110)
U 48.5 (-110)
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Michigan Wolverines
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MICH
+580
-880
+15.5 (-105)
-15.5 (-115)
O 41.5 (-105)
U 41.5 (-115)
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UTSA Roadrunners
Temple Owls
10/4/25 1PM
UTSA
TEMPLE
-210
+172
-5.5 (-115)
+5.5 (-105)
O 56.5 (-110)
U 56.5 (-110)
Oct 4, 2025 3:30PM EDT
Vanderbilt Commodores
Alabama Crimson Tide
10/4/25 3:30PM
VANDY
BAMA
+360
-480
+11.5 (-102)
-11.5 (-120)
O 51.5 (-110)
U 51.5 (-110)
Oct 4, 2025 3:30PM EDT
Washington Huskies
Maryland Terrapins
10/4/25 3:30PM
WASH
MD
 
 
-7 (-110)
+7 (-110)
Oct 4, 2025 3:30PM EDT
Boise State Broncos
Notre Dame Fighting Irish
10/4/25 3:30PM
BOISE
ND
+365
-490
+13.5 (-105)
-13.5 (-115)
O 61.5 (-110)
U 61.5 (-110)
Oct 4, 2025 3:30PM EDT
Texas Longhorns
Florida Gators
10/4/25 3:30PM
TEXAS
FLA
-300
+240
-7.5 (-110)
+7.5 (-110)
O 46.5 (-110)
U 46.5 (-110)
Oct 4, 2025 4:00PM EDT
Kent State Golden Flashes
Oklahoma Sooners
10/4/25 4PM
KENT
OKLA
 
 
+45.5 (-110)
-45.5 (-110)
O 52.5 (-115)
U 52.5 (-105)
Oct 4, 2025 4:00PM EDT
Michigan State Spartans
Nebraska Cornhuskers
10/4/25 4PM
MICHST
NEB
+360
-480
+12.5 (-105)
-12.5 (-115)
O 53.5 (-110)
U 53.5 (-110)

CFB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Purdue Boilermakers vs. Michigan State Spartans on November 22, 2024 at Spartan Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our CFB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
TULANE@OLEMISS MISS -11.5 54.3% 4 WIN
UNC@UCF UCF -6.5 54.4% 4 WIN
ARKST@KENSAW KENSAW +4.5 54.5% 4 WIN
ILL@IND IND -6 53.2% 3 WIN
SELOU@LSU LSU -47.5 55.3% 5 LOSS
TNMART@MIZZST MIZZST -14.5 56.2% 6 WIN
FRESNO@HAWAII HAWAII +3 56.6% 6 WIN
MRSHL@MTSU MTSU +2.5 56.8% 6 LOSS
MICH@NEB NEB +1.5 57.3% 7 LOSS
WASH@WASHST DENZEL BOSTON UNDER 69.5 RECV YDS 56.2% 6 LOSS
IOWA@RUT ANTWAN RAYMOND OVER 0.5 TOUCHDOWNS 54.4% 4 WIN
GEORGIA@TENN UNDER 50.5 55.5% 6 LOSS
ARK@OLEMISS MISS -225 72.0% 9 WIN
DUKE@TULANE TULANE -120 56.5% 4 WIN
ARK@OLEMISS MISS -6.5 53.9% 3 LOSS
AKRON@UAB UAB -11 54.7% 4 LOSS
UCONN@DEL DEL +9.5 55.0% 5 WIN
APLST@USM USM +4 55.3% 6 WIN
MERIMK@KENSAW KENSAW -13.5 56.2% 7 WIN
UMASS@IOWA IOWA -34.5 56.4% 7 WIN
UMASS@IOWA JAZIUN PATTERSON UNDER 0.5 RUSH TDS 54.8% 4 WIN
NMEX@UCLA NICO IAMALEAVA UNDER 31.5 PASS ATT 53.4% 3 LOSS
KSTATE@ARIZ ARIZ +1.5 56.1% 6 WIN
BC@MICHST NICK MARSH OVER 47.5 RCV YDS 53.6% 3 WIN
ARIZST@MISSST MISSST +7 54.2% 4 WIN
TULSA@NMEXST NMEXST +3.5 56.9% 6 WIN
UCLA@UNLV OVER 54.5 56.2% 6 LOSS
FRESNO@OREGST FRESNO +1.5 54.7% 4 WIN
VANDY@VATECH VANDY +2.5 55.8% 5 WIN
JMAD@LVILLE LVILLE -14.5 54.0% 3 LOSS
TCU@UNC JOSEPH MANJACK OVER 37.5 RECV YDS 53.8% 3 LOSS
ND@MIAMI MIAMI +3 55.2% 6 WIN
MISSST@USM USM +14.5 56.0% 6 LOSS
UTAH@UCLA UCLA +5.5 56.2% 6 LOSS
CAL@OREGST OREGST +1.5 55.1% 5 LOSS
FAU@MD MD -13.5 55.2% 5 WIN
GAS@FRESNO FRESNO +2 55.2% 5 WIN
TOLEDO@UK UK -9.5 56.2% 6 LOSS
AUSTPEAY@MTSU PEAY +12.5 56.2% 6 WIN
LSU@CLEM GARRETT NUSSMEIER OVER 23.5 PASS COMP 54.1% 3 WIN
WMICH@MICHST WMICH +21.5 56.2% 6 WIN
ND@OHIOST WILL HOWARD INTERCEPTIONS OVER 0.5 54.80% 4 LOSS
OHIOST@TEXAS WILL HOWARD PASS + RUSH YDS UNDER 262.5 54.70% 4 LOSS
GEORGIA@TEXAS TEXAS -144 54.40% 4 LOSS
AUBURN@BAMA PAYTON THORNE PASS TDS - UNDER 1.5 53.20% 3 WIN
PURDUE@IND IND -28.5 53.90% 3 WIN
FRESNO@UCLA T.J. HARDEN LONGEST RUSH OVER 17.5 YDS 54.50% 4 LOSS
TENN@VANDY VANDY +10.5 54.90% 4 LOSS
WVU@TXTECH TXTECH -2.5 54.60% 4 WIN
SC@CLEM CLEM -130 58.70% 4 LOSS
TCU@CINCY TCU -3 54.20% 4 WIN