Louisville vs Notre Dame Prediction — AI Finds CAN'T MISS CFB Lines & Props (Sep 28)
Updated: 2024-09-21T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The Louisville Cardinals (3-0) will face the Notre Dame Fighting Irish (3-1) on September 28, 2024, at Notre Dame Stadium. Notre Dame is a 6-point favorite, and both teams are eager to solidify their national rankings as they approach the midpoint of the season.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.
GAME INFO
Date: Sep 28, 2024
Start Time: 3:30 PM EST
Venue: Notre Dame Stadium
Fighting Irish Record: (3-1)
Cardinals Record: (3-0)
OPENING ODDS
LVILLE Moneyline: +183
ND Moneyline: -223
LVILLE Spread: +6
ND Spread: -6.0
Over/Under: 48.5
LVILLE
Betting Trends
- Louisville has a 2-1 record against the spread (ATS) this season. The Cardinals have won their last eight September games, showing strength early in the season. However, they have struggled in recent road games against ranked teams, going 1-4 ATS in their last five such matchups.
ND
Betting Trends
- Notre Dame holds a 2-2 ATS record this season and is particularly strong at home. They have covered the spread in 12 of their last 13 games when favored against AP-ranked teams. Additionally, Notre Dame has a long-standing undefeated record at home against ACC opponents.
MATCHUP TRENDS
- Notre Dame has won 18 consecutive home games against ACC teams. This historical dominance suggests they have a significant edge when playing at home against conference opponents.
LVILLE vs. ND
Best Prop Bet
- Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.
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Louisville vs Notre Dame Prediction & Odds:
Free CFB Betting Insights for 9/28/24
The Fighting Irish offense is complemented by their powerful rushing attack, spearheaded by Jeremiyah Love, who has racked up 339 rushing yards and four touchdowns this season. Louisville, undefeated at 3-0, enters this contest with plenty of confidence. Led by quarterback Tyler Shough, who has thrown for 850 yards and 8 touchdowns, the Cardinals have averaged an impressive 47.3 points per game. Louisville’s offense is dynamic, featuring a balanced attack with a solid rushing game led by Isaac Brown, who averages 10.8 yards per carry.
However, Louisville’s defensive unit will be tested against Notre Dame’s physical offensive line and balanced play calling. The key to this game will be whether Louisville’s explosive offense can penetrate Notre Dame’s stout defense, which is allowing just 14.5 points per game. The Cardinals will need to avoid costly turnovers and stay efficient in the red zone if they hope to keep this game close. On the other hand, Notre Dame will likely lean on their ground game and solid defense to control the tempo and grind out a victory.
Unreal catch 🤯🤯🤯#GoCards pic.twitter.com/NmPtzauLaM
— Louisville Football (@LouisvilleFB) September 24, 2024
Louisville Cardinals CFB Preview
Louisville enters this game undefeated, but this will be their toughest test so far. The Cardinals have relied on an efficient and explosive offense, with quarterback Tyler Shough leading the way. Shough has thrown for 850 yards and eight touchdowns with no interceptions, showcasing his ability to make smart decisions under pressure. The running game, led by Isaac Brown and Keyjuan Brown, has added balance to the offense, keeping defenses guessing. Louisville’s defense, while solid, has shown vulnerabilities against the pass. They’ll need a much-improved effort to slow down Notre Dame’s rushing attack and limit explosive plays. The Cardinals are allowing just 268.7 total yards per game, but they haven’t faced an offense as physical as Notre Dame’s. For Louisville to pull off the upset, they’ll need to win the turnover battle and capitalize on any mistakes Notre Dame makes. Containing Riley Leonard’s dual-threat ability and keeping Notre Dame’s rushing attack in check will be paramount. If Louisville’s offense can maintain its efficiency and keep the game close into the fourth quarter, they may be able to cover the spread or even steal a win on the road.
Credit: USA TODAY/IMAGN
Notre Dame Fighting Irish CFB Preview
The Notre Dame Fighting Irish come into this game with momentum following back-to-back wins. Quarterback Riley Leonard has been a dual threat, accounting for both passing and rushing touchdowns, though his passing game has struggled at times with only one passing touchdown and two interceptions. Notre Dame’s offense is highly reliant on their rushing attack, where Leonard and running back Jeremiyah Love have been the stars. The Irish average 7.5 yards per carry and will look to impose their will on Louisville’s defense, especially in short-yardage situations. Defensively, Notre Dame has been stellar, ranking among the top units in the nation in points allowed per game. They’ve been particularly effective against the pass, allowing only one passing touchdown all season. Notre Dame’s defensive line, led by Jack Kiser, has also been disruptive, with nine sacks through four games. The Irish will need to maintain their defensive intensity to stifle Louisville’s high-powered offense. Notre Dame’s keys to victory lie in dominating the line of scrimmage and forcing Louisville into third-and-long situations, where they can apply pressure on quarterback Tyler Shough. If the Irish control time of possession, they should cover the 6-point spread comfortably.
2️⃣4️⃣
— Notre Dame Football (@NDFootball) September 25, 2024
𝘛𝘩𝘦 𝘊𝘢𝘮𝘱𝘣𝘦𝘭𝘭 𝘛𝘳𝘰𝘱𝘩𝘺 𝘳𝘦𝘤𝘰𝘨𝘯𝘪𝘻𝘦𝘴 𝘢𝘯 𝘪𝘯𝘥𝘪𝘷𝘪𝘥𝘶𝘢𝘭 𝘢𝘴 𝘵𝘩𝘦 𝘢𝘣𝘴𝘰𝘭𝘶𝘵𝘦 𝘣𝘦𝘴𝘵 𝘧𝘰𝘰𝘵𝘣𝘢𝘭𝘭 𝘴𝘤𝘩𝘰𝘭𝘢𝘳-𝘢𝘵𝘩𝘭𝘦𝘵𝘦 𝘪𝘯 𝘵𝘩𝘦 𝘯𝘢𝘵𝘪𝘰𝘯 𝘧𝘰𝘳 𝘩𝘪𝘴 𝘤𝘰𝘮𝘣𝘪𝘯𝘦𝘥 𝘢𝘤𝘢𝘥𝘦𝘮𝘪𝘤 𝘴𝘶𝘤𝘤𝘦𝘴𝘴, 𝘧𝘰𝘰𝘵𝘣𝘢𝘭𝘭… pic.twitter.com/t1fITiOJUM
Louisville vs. Notre Dame Prop Picks (AI)
Louisville vs. Notre Dame Prediction (AI)
Remi, our AI sports algorithm, has been pouring over mountains of data from every angle between the Cardinals and Fighting Irish and using recursive machine learning and kick-ass AI to examine the data to a single cover probability.
The Algorithm has been most focused on the linear correlation of emphasis emotional bettors often put on coaching factors between a Cardinals team going up against a possibly strong Fighting Irish team. Trends look to say the true game analytics appear to reflect a strong lean against one Vegas line specifically.
Unlock this in-depth AI prediction and all of our CFB AI picks for FREE now.
Below is our current AI Louisville vs Notre Dame picks, computer picks Cardinals vs Fighting Irish, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
|---|---|---|---|---|---|---|
| ACTIVE PICKS LOCKED - SEE NOW | ||||||
These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full CFB schedule.
Cardinals Betting Trends
Louisville has a 2-1 record against the spread (ATS) this season. The Cardinals have won their last eight September games, showing strength early in the season. However, they have struggled in recent road games against ranked teams, going 1-4 ATS in their last five such matchups.
Fighting Irish Betting Trends
Notre Dame holds a 2-2 ATS record this season and is particularly strong at home. They have covered the spread in 12 of their last 13 games when favored against AP-ranked teams. Additionally, Notre Dame has a long-standing undefeated record at home against ACC opponents.
Cardinals vs. Fighting Irish Matchup Trends
Notre Dame has won 18 consecutive home games against ACC teams. This historical dominance suggests they have a significant edge when playing at home against conference opponents.
Louisville vs. Notre Dame Game Info
What time does Louisville vs Notre Dame start on September 28, 2024?
Louisville vs Notre Dame starts on September 28, 2024 at 3:30 PM EST.
Where is Louisville vs Notre Dame being played?
Venue: Notre Dame Stadium.
What are the opening odds for Louisville vs Notre Dame?
Spread: Notre Dame -6.0
Moneyline: Louisville +183, Notre Dame -223
Over/Under: 48.5
What are the records for Louisville vs Notre Dame?
Louisville: (3-0) | Notre Dame: (3-1)
What is the AI best bet for Louisville vs Notre Dame?
Remi's searched hard and is crunching tons of data, but hasn't found a good Prop Bet yet for this game.. Prices move—always shop for the best number.
What are Louisville vs Notre Dame trending bets?
Notre Dame has won 18 consecutive home games against ACC teams. This historical dominance suggests they have a significant edge when playing at home against conference opponents.
What are Louisville trending bets?
LVILLE trend: Louisville has a 2-1 record against the spread (ATS) this season. The Cardinals have won their last eight September games, showing strength early in the season. However, they have struggled in recent road games against ranked teams, going 1-4 ATS in their last five such matchups.
What are Notre Dame trending bets?
ND trend: Notre Dame holds a 2-2 ATS record this season and is particularly strong at home. They have covered the spread in 12 of their last 13 games when favored against AP-ranked teams. Additionally, Notre Dame has a long-standing undefeated record at home against ACC opponents.
Where can I find AI Picks for Louisville vs Notre Dame?
See our latest CFB picks and odds pages for 2024 to compare prices before you bet.
Louisville vs. Notre Dame Odds
AI algorithm Remi is pouring through loads of stats on each team. In fact, anytime the Louisville vs Notre Dame trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme altitude rarely follow normal, predictable betting trends.
Louisville vs Notre Dame Opening Odds
LVILLE Moneyline:
+183 ND Moneyline: -223
LVILLE Spread: +6
ND Spread: -6.0
Over/Under: 48.5
Louisville vs Notre Dame Live Odds
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O 47 (-110)
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Nov 11, 2025 8:00PM EST
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O 47 (-110)
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Nov 12, 2025 7:00PM EST
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O 43 (-110)
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Nov 12, 2025 7:00PM EST
Buffalo Bulls
Central Michigan Chippewas
11/12/25 7PM
BUFF
CMICH
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–
–
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-105
-115
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+1 (-110)
-1 (-110)
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O 43 (-110)
U 43 (-110)
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Nov 12, 2025 7:00PM EST
Toledo Rockets
Miami Ohio Redhawks
11/12/25 7PM
TOLEDO
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–
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-190
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-4 (-110)
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O 44.5 (-115)
U 44.5 (-105)
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Nov 13, 2025 7:30PM EST
Troy Trojans
Old Dominion Monarchs
11/13/25 7:30PM
TROY
OLDDOM
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–
–
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+325
-425
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+11.5 (-115)
-11.5 (-105)
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O 52.5 (-110)
U 52.5 (-110)
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Nov 14, 2025 7:30PM EST
Clemson Tigers
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11/14/25 7:30PM
CLEM
LVILLE
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–
–
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+130
-155
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+3 (-110)
-3 (-110)
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O 50.5 (-110)
U 50.5 (-110)
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Nov 14, 2025 9:00PM EST
Minnesota Golden Gophers
Oregon Ducks
11/14/25 9PM
MINN
OREG
|
–
–
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+1400
-2800
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+25.5 (-115)
-25.5 (-105)
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O 44.5 (-110)
U 44.5 (-110)
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Nov 15, 2025 12:00PM EST
Air Force Falcons
UConn Huskies
11/15/25 12PM
AF
UCONN
|
–
–
|
+230
-285
|
+7 (-105)
-7 (-115)
|
O 63.5 (-110)
U 63.5 (-110)
|
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Nov 15, 2025 12:00PM EST
Michigan Wolverines
Northwestern Wildcats
11/15/25 12PM
MICH
NWEST
|
–
–
|
-500
+370
|
-12.5 (-110)
+12.5 (-110)
|
O 41 (-110)
U 41 (-110)
|
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Nov 15, 2025 12:00PM EST
UTSA Roadrunners
Charlotte 49ers
11/15/25 12PM
UTSA
CHARLO
|
–
–
|
-1000
+660
|
-18.5 (-110)
+18.5 (-110)
|
O 60.5 (-110)
U 60.5 (-110)
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Nov 15, 2025 12:00PM EST
South Florida Bulls
Navy Midshipmen
11/15/25 12PM
SFLA
NAVY
|
–
–
|
-400
+305
|
-10.5 (-105)
+10.5 (-115)
|
O 65 (-110)
U 65 (-110)
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Nov 15, 2025 12:00PM EST
Arizona Wildcats
Cincinnati Bearcats
11/15/25 12PM
ARIZ
CINCY
|
–
–
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+185
-225
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+6.5 (-110)
-6.5 (-110)
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O 56 (-110)
U 56 (-110)
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Nov 15, 2025 12:00PM EST
Eastern Michigan Eagles
Ball State Cardinals
11/15/25 12PM
EMICH
BALLST
|
–
–
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-130
+110
|
-2.5 (-110)
+2.5 (-110)
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O 50.5 (-110)
U 50.5 (-110)
|
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Nov 15, 2025 12:00PM EST
Notre Dame Fighting Irish
Pittsburgh Panthers
11/15/25 12PM
ND
PITT
|
–
–
|
-425
+325
|
-11 (-110)
+11 (-110)
|
O 55 (-110)
U 55 (-110)
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Nov 15, 2025 12:00PM EST
South Carolina Gamecocks
Texas A&M Aggies
11/15/25 12PM
SC
TEXAM
|
–
–
|
+760
-1200
|
+19.5 (-110)
-19.5 (-110)
|
O 48 (-110)
U 48 (-110)
|
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Nov 15, 2025 12:00PM EST
Wisconsin Badgers
Indiana Hoosiers
11/15/25 12PM
WISC
IND
|
–
–
|
+3500
-20000
|
+29.5 (-110)
-29.5 (-110)
|
O 44.5 (-110)
U 44.5 (-110)
|
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Nov 15, 2025 12:00PM EST
Kansas State Wildcats
Oklahoma State Cowboys
11/15/25 12PM
KSTATE
OKLAST
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–
–
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-1200
+760
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-19.5 (-110)
+19.5 (-110)
|
O 52.5 (-110)
U 52.5 (-110)
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Nov 15, 2025 12:45PM EST
Arkansas Razorbacks
LSU Tigers
11/15/25 12:45PM
ARK
LSU
|
–
–
|
+170
-205
|
+5.5 (-115)
-5.5 (-105)
|
O 55.5 (-110)
U 55.5 (-110)
|
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Nov 15, 2025 1:00PM EST
Oregon State Beavers
Tulsa Golden Hurricane
11/15/25 1PM
OREGST
TULSA
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–
–
|
-130
+110
|
-2.5 (-110)
+2.5 (-110)
|
O 48 (-110)
U 48 (-110)
|
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Nov 15, 2025 1:00PM EST
West Virginia Mountaineers
Arizona State Sun Devils
11/15/25 1PM
WVU
ARIZST
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–
–
|
+355
-475
|
+11.5 (-110)
-11.5 (-110)
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O 48 (-110)
U 48 (-110)
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|
Nov 15, 2025 1:30PM EST
Tennessee Tech Golden Eagles
Kentucky Wildcats
11/15/25 1:30PM
TNTECH
UK
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–
–
|
+1200
-2800
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+22.5 (-110)
-22.5 (-110)
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O 52.5 (-110)
U 52.5 (-110)
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Nov 15, 2025 2:00PM EST
Marshall Thundering Herd
Georgia State Panthers
11/15/25 2PM
MARSH
GAST
|
–
–
|
-285
+230
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-7.5 (+100)
+7.5 (-120)
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O 63.5 (-110)
U 63.5 (-110)
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Nov 15, 2025 2:00PM EST
North Texas Mean Green
UAB Blazers
11/15/25 2PM
NOTEX
UAB
|
–
–
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-1000
+660
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-18.5 (-110)
+18.5 (-110)
|
O 69.5 (-110)
U 69.5 (-110)
|
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Nov 15, 2025 3:00PM EST
UTEP Miners
Missouri State Bears
11/15/25 3PM
UTEP
MIZZST
|
–
–
|
+160
-195
|
+4.5 (-115)
-4.5 (-105)
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O 50 (-110)
U 50 (-110)
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Nov 15, 2025 3:00PM EST
Colorado State Rams
New Mexico Lobos
11/15/25 3PM
COLOST
NMEX
|
–
–
|
+460
-650
|
+14.5 (-115)
-14.5 (-105)
|
O 53.5 (-110)
U 53.5 (-110)
|
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Nov 15, 2025 3:30PM EST
San Jose State Spartans
Nevada Wolf Pack
11/15/25 3:30PM
SJST
NEVADA
|
–
–
|
-340
+265
|
-9.5 (-110)
+9.5 (-110)
|
O 52.5 (-105)
U 52.5 (-115)
|
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Nov 15, 2025 3:30PM EST
South Alabama Jaguars
UL Monroe Warhawks
11/15/25 3:30PM
SBAMA
MONROE
|
–
–
|
-200
+165
|
-4.5 (-110)
+4.5 (-110)
|
O 51 (-110)
U 51 (-110)
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Nov 15, 2025 3:30PM EST
UCF Knights
Texas Tech Red Raiders
11/15/25 3:30PM
UCF
TXTECH
|
–
–
|
+1200
-2200
|
+24 (-110)
-24 (-110)
|
O 47.5 (-115)
U 47.5 (-105)
|
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|
Nov 15, 2025 3:30PM EST
NC State Wolfpack
Miami Hurricanes
11/15/25 3:30PM
NCST
MIAMI
|
–
–
|
+460
-650
|
+14.5 (-110)
-14.5 (-110)
|
O 55.5 (-110)
U 55.5 (-110)
|
|
|
Nov 15, 2025 3:30PM EST
Maryland Terrapins
Illinois Fighting Illini
11/15/25 3:30PM
MD
ILL
|
–
–
|
+490
-700
|
+15.5 (-110)
-15.5 (-110)
|
O 53.5 (-110)
U 53.5 (-110)
|
|
|
Nov 15, 2025 3:30PM EST
Georgia Tech Yellow Jackets
Boston College Eagles
11/15/25 3:30PM
GATECH
BC
|
–
–
|
-850
+580
|
-17 (-110)
+17 (-110)
|
O 58.5 (-110)
U 58.5 (-110)
|
|
|
Nov 15, 2025 3:30PM EST
Penn State Nittany Lions
Michigan State Spartans
11/15/25 3:30PM
PSU
MICHST
|
–
–
|
-280
+225
|
-7.5 (-105)
+7.5 (-115)
|
O 50.5 (-110)
U 50.5 (-110)
|
|
|
Nov 15, 2025 3:30PM EST
MTSU Blue Raiders
Western Kentucky Hilltoppers
11/15/25 3:30PM
MTSU
WKY
|
–
–
|
-550
|
-13.5 (-115)
|
O 56 (-110)
U 56 (-110)
|
|
|
Nov 15, 2025 3:30PM EST
Virginia Cavaliers
Duke Blue Devils
11/15/25 3:30PM
UVA
DUKE
|
–
–
|
+190
-235
|
+6.5 (-110)
-6.5 (-110)
|
O 57.5 (-110)
U 57.5 (-110)
|
|
|
Nov 15, 2025 3:30PM EST
Iowa Hawkeyes
USC Trojans
11/15/25 3:30PM
IOWA
USC
|
–
–
|
+200
-245
|
+6.5 (-105)
-6.5 (-115)
|
O 49.5 (-110)
U 49.5 (-110)
|
|
|
Nov 15, 2025 3:30PM EST
App State Mountaineers
James Madison Dukes
11/15/25 3:30PM
APPST
JMAD
|
–
–
|
-1500
|
-21 (-110)
|
O 54 (-110)
U 54 (-110)
|
|
|
Nov 15, 2025 3:30PM EST
Texas State Bobcats
USM Golden Eagles
11/15/25 3:30PM
TEXST
USM
|
–
–
|
+175
|
+5.5 (-110)
|
O 65.5 (-110)
U 65.5 (-110)
|
|
|
Nov 15, 2025 3:30PM EST
Oklahoma Sooners
Alabama Crimson Tide
11/15/25 3:30PM
OKLA
BAMA
|
–
–
|
+180
-220
|
+6 (-110)
-6 (-110)
|
O 45.5 (-110)
U 45.5 (-110)
|
|
|
Nov 15, 2025 4:00PM EST
Florida Atlantic Owls
Tulane Green Wave
11/15/25 4PM
FAU
TULANE
|
–
–
|
+600
-900
|
+17.5 (-110)
-17.5 (-110)
|
O 63 (-110)
U 63 (-110)
|
|
|
Nov 15, 2025 4:00PM EST
Memphis Tigers
East Carolina Pirates
11/15/25 4PM
MEMP
ECAR
|
–
–
|
+120
-145
|
+3 (-115)
-3 (-105)
|
O 59.5 (-110)
U 59.5 (-110)
|
|
|
Nov 15, 2025 4:15PM EST
New Mexico State Aggies
Tennessee Volunteers
11/15/25 4:15PM
NMEXST
TENN
|
–
–
|
+8000
-50000
|
+40 (-110)
-40 (-110)
|
O 61.5 (-110)
U 61.5 (-110)
|
|
|
Nov 15, 2025 4:30PM EST
North Carolina Tar Heels
Wake Forest Demon Deacons
11/15/25 4:30PM
UNC
WAKE
|
–
–
|
+190
-235
|
+6.5 (-110)
-6.5 (-110)
|
O 39.5 (-110)
U 39.5 (-110)
|
|
|
Nov 15, 2025 5:00PM EST
Liberty Flames
FIU Panthers
11/15/25 5PM
LIB
FIU
|
–
–
|
-145
|
-3 (-105)
|
O 53 (-110)
U 53 (-110)
|
|
|
Nov 15, 2025 6:00PM EST
Coastal Carolina Chanticleers
Georgia Southern Eagles
11/15/25 6PM
COAST
GASO
|
–
–
|
+115
-140
|
+2.5 (-105)
-2.5 (-115)
|
O 60.5 (-110)
U 60.5 (-110)
|
|
|
Nov 15, 2025 7:00PM EST
Utah State Aggies
UNLV Rebels
11/15/25 7PM
UTAHST
UNLV
|
–
–
|
+190
-235
|
+6 (-110)
-6 (-110)
|
O 71 (-110)
U 71 (-110)
|
|
|
Nov 15, 2025 7:00PM EST
Florida Gators
Ole Miss Rebels
11/15/25 7PM
FLA
OLEMISS
|
–
–
|
+520
-750
|
+16.5 (-110)
-16.5 (-110)
|
O 54 (-110)
U 54 (-110)
|
|
|
Nov 15, 2025 7:00PM EST
Delaware Blue Hens
Sam Houston State Bearkats
11/15/25 7PM
DEL
SAMST
|
–
–
|
-350
+275
|
-9.5 (-115)
+9.5 (-105)
|
O 56.5 (-110)
U 56.5 (-110)
|
|
|
Nov 15, 2025 7:00PM EST
Utah Utes
Baylor Bears
11/15/25 7PM
UTAH
BAYLOR
|
–
–
|
-310
+245
|
-8 (-110)
+8 (-110)
|
O 60 (-110)
U 60 (-110)
|
|
|
Nov 15, 2025 7:00PM EST
Purdue Boilermakers
Washington Huskies
11/15/25 7PM
PURDUE
WASH
|
–
–
|
+600
-900
|
+17 (-110)
-17 (-110)
|
O 53.5 (-110)
U 53.5 (-110)
|
|
|
Nov 15, 2025 7:30PM EST
Virginia Tech Hokies
Florida State Seminoles
11/15/25 7:30PM
VATECH
FSU
|
–
–
|
+400
-550
|
+13.5 (-105)
-13.5 (-115)
|
O 55.5 (-105)
U 55.5 (-115)
|
|
|
Nov 15, 2025 7:30PM EST
Texas Longhorns
Georgia Bulldogs
11/15/25 7:30PM
TEXAS
UGA
|
–
–
|
+180
-220
|
+6 (-110)
-6 (-110)
|
O 48 (-110)
U 48 (-110)
|
|
|
Nov 15, 2025 7:30PM EST
UCLA Bruins
Ohio State Buckeyes
11/15/25 7:30PM
UCLA
OHIOST
|
–
–
|
+3000
-10000
|
+32 (-110)
-32 (-110)
|
O 48.5 (-110)
U 48.5 (-110)
|
|
|
Nov 15, 2025 7:45PM EST
Mississippi State Bulldogs
Missouri Tigers
11/15/25 7:45PM
MISSST
MIZZOU
|
–
–
|
+220
-275
|
+7 (-110)
-7 (-110)
|
O 51.5 (-110)
U 51.5 (-110)
|
|
|
Nov 15, 2025 8:00PM EST
Kennesaw State Owls
Jacksonville State Gamecocks
11/15/25 8PM
KENSAW
JAXST
|
–
–
|
-165
+135
|
-3.5 (+105)
+3.5 (-125)
|
O 53.5 (-115)
U 53.5 (-105)
|
|
|
Nov 15, 2025 10:00PM EST
Louisiana Tech Bulldogs
Washington State Cougars
11/15/25 10PM
LATECH
WASHST
|
–
–
|
+245
-310
|
+8 (-110)
-8 (-110)
|
O 45.5 (-105)
U 45.5 (-115)
|
|
|
Nov 15, 2025 10:15PM EST
TCU Horned Frogs
BYU Cougars
11/15/25 10:15PM
TCU
BYU
|
–
–
|
+165
-200
|
+4.5 (-110)
-4.5 (-110)
|
O 52.5 (-110)
U 52.5 (-110)
|
|
|
Nov 15, 2025 10:30PM EST
Boise State Broncos
San Diego State Aztecs
11/15/25 10:30PM
BOISE
SDGST
|
–
–
|
+120
-145
|
+3 (-115)
-3 (-105)
|
O 41 (-110)
U 41 (-110)
|
|
|
Nov 15, 2025 10:30PM EST
Wyoming Cowboys
Fresno State Bulldogs
11/15/25 10:30PM
WYO
FRESNO
|
–
–
|
+145
-175
|
+3.5 (-110)
-3.5 (-110)
|
O 40 (-110)
U 40 (-110)
|
|
|
Dec 6, 2025 8:00PM EST
Ohio State Buckeyes
Indiana Hoosiers
12/6/25 8PM
OHIOST
IND
|
–
–
|
-225
+180
|
-5.5 (-122)
+5.5 (+100)
|
O 49.5 (-110)
U 49.5 (-110)
|
CFB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Louisville Cardinals vs. Notre Dame Fighting Irish on September 28, 2024 at Notre Dame Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our CFB odds pages, and compare prices before you place a bet.
| CFB |
LEAN | %WIN | UNITS | RESULT |
|---|---|---|---|---|
| JAXST@UTEP | JAXST -105 | 57.0% | 7 | WIN |
| FSU@CLEM | CLEM -118 | 57.1% | 5 | WIN |
| UNLV@COLOST | UNLV -4 | 55.2% | 5 | WIN |
| OREG@IOWA | IOWA +6.5 | 53.3% | 2 | WIN |
| NEB@UCLA | NEB +1.5 | 55.8% | 5 | WIN |
| AUBURN@VANDY | AUBURN +6.5 | 56.2% | 6 | LOSS |
| KENSAW@NMEXST | NMEXST +10 | 56.5% | 6 | WIN |
| STNFRD@UNC | STNFRD +7.5 | 53.8% | 3 | WIN |
| DUKE@UCONN | UCONN +8.5 | 57.9% | 7 | WIN |
| NEVADA@UTAHST | NEVADA +9.5 | 55.9% | 5 | LOSS |
| SAMST@OREGST | SAMST +21 | 57.7% | 7 | WIN |
| NEB@UCLA | NICO IAMALEAVA UNDER 180.5 PASS YDS | 56.6% | 6 | LOSS |
| HOU@UCF | HOU -112 | 58.0% | 6 | WIN |
| GASTHRN@APPST | GASTHRN +180 | 36.5% | 2 | WIN |
| KENTST@BALLST | BALLST -2.5 | 54.5% | 4 | WIN |
| WAKE@FSU | WAKE +10.5 | 56.4% | 6 | LOSS |
| WYO@SDGST | SDGST -10.5 | 56.7% | 7 | WIN |
| OKLA@TENN | TENN -130 | 58.3% | 5 | LOSS |
| GATECH@NCST | GATECH -5 | 56.4% | 6 | LOSS |
| MIAMI@SMU | MIAMI -10 | 54.3% | 4 | LOSS |
| DEL@LIB | DEL +3.5 | 57.6% | 7 | LOSS |
| NMEXST@WKY | NMEXST +8.5 | 57.9% | 7 | LOSS |
| IND@MD | MD +21.5 | 54.6% | 4 | LOSS |
| CINCY@UTAH | CINCY +11 | 57.6% | 7 | LOSS |
| OLDDOM@LAMON | LAMON +17 | 58.4% | 8 | LOSS |
| VANDY@TEXAS | OVER 46.5 | 53.7% | 2 | WIN |
| MICHST@MINN | MAKHI FRAZIER UNDER 52.5 RUSH YDS | 55.2% | 5 | WIN |
| UNC@CUSE | UNC +110 | 50.4% | 2 | WIN |
| MRSHL@COASTAL | COASTAL +7 | 53.3% | 3 | WIN |
| FIU@MIZZST | FIU +3.5 | 53.9% | 3 | LOSS |
| TEXAM@LSU | MARCEL REED OVER 0.5 INT | 55.5% | 5 | WIN |
| RUT@PURDUE | RUT +103 | 54.0% | 4 | WIN |
| TOLEDO@WASHST | TOLEDO -110 | 56.1% | 6 | LOSS |
| AUBURN@ARK | ARK -128 | 60.5% | 8 | LOSS |
| NCST@PITT | NCST +6.5 | 54.9% | 4 | LOSS |
| OHIO@EMICH | EMICH +12 | 54.1% | 4 | WIN |
| TCU@WVU | WVU +16.5 | 54.6% | 4 | WIN |
| COLO@UTAH | COLO +14.5 | 57.7% | 7 | LOSS |
| HOU@ARIZST | HOU +7.5 | 57.1% | 7 | WIN |
| UVA@UNC | UNC +11.5 | 56.2% | 6 | WIN |
| MINN@IOWA | MINN +9.5 | 57.3% | 7 | LOSS |
| UCONN@RICE | RICE +10.5 | 57.1% | 6 | WIN |
| FAU@NAVY | FAU +14.5 | 56.7% | 6 | WIN |
| LAMON@USM | LAMON +13.5 | 56.4% | 6 | LOSS |
| BOISE@NEVADA | NEVADA +21.5 | 56.8% | 6 | WIN |
| SALA@GAST | GAST +6.5 | 54.3% | 4 | LOSS |
| MIZZST@NMEXST | MIZZST -108 | 54.4% | 4 | WIN |
| KENSAW@FIU | FIU +3 | 53.7% | 3 | LOSS |
| KENTST@TOLEDO | KENTST +24.5 | 56.9% | 6 | LOSS |
| OLDDOM@JMAD | JMAD -125 | 57.9% | 7 | WIN |
| TXTECH@ARIZST | TXTECH -6.5 | 54.2% | 4 | LOSS |