Wolfpack vs. Tigers
Prediction, Odds & Props
Sep 21 | CFB AI Picks
Updated: 2024-09-14T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The NC State Wolfpack will take on the Clemson Tigers on September 21, 2024, at Memorial Stadium in Clemson, SC. Both teams are looking to gain an early edge in ACC play, with NC State coming off a 2-1 start and Clemson sitting at 1-1. This matchup is critical for both programs as they aim to establish themselves as ACC contenders.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Sep 21, 2024
Start Time: 12:00 PM EST
Venue: Memorial Stadium
Tigers Record: (1-1)
Wolfpack Record: (2-1)
OPENING ODDS
NCST Moneyline: +544
CLEM Moneyline: -794
NCST Spread: +17
CLEM Spread: -17.0
Over/Under: 48
NCST
Betting Trends
- NC State is 0-3 against the spread (ATS) this season. Despite having a winning record, the Wolfpack has struggled to cover the spread in their first three games. Their performances have been inconsistent, particularly on defense, which has allowed 30.7 points per game on average.
CLEM
Betting Trends
- Clemson is 1-1 ATS this season. The Tigers covered the spread in their dominant 66-20 win over Appalachian State but failed to cover in a loss to Georgia. The team’s performance has been up and down, and they’ll be looking for more consistency against NC State.
MATCHUP TRENDS
- Both teams have shown vulnerabilities on defense, with NC State allowing 386 yards per game and Clemson allowing 410.5 yards per game. With both defenses struggling to contain opponents, betting on the over could be an interesting option.
NCST vs. CLEM
Best Prop Bet
- Remi's is still searching and crunching tons of data to find the perfect prop bet. Stay tuned .
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NC State vs Clemson Prediction & Odds:
Free CFB Betting Insights for 9/21/24
NC State, under head coach Dave Doeren, has been relying on quarterback Grayson McCall, who has thrown for 476 yards this season. The Wolfpack’s offense has been somewhat inconsistent, averaging 347.3 yards per game. Their rushing game, led by Jordan Waters, has not been as effective, and this has put more pressure on the passing game to deliver. For NC State to compete against Clemson, they will need to improve their third-down conversion rate, which currently sits at 44.7%. Defensively, both teams have had their struggles. Clemson has allowed 410.5 yards per game, particularly struggling against the pass. Their secondary will need to step up to prevent big plays from NC State’s passing attack. Conversely, NC State’s defense has allowed 386 yards per game and will be tested by Clemson’s balanced offense. The Wolfpack will need to create turnovers and limit Clemson’s time of possession to keep the game close.
All roads lead to conference play.#1Pack1Goal pic.twitter.com/LNXVlM93Ud
— NC State Football (@PackFootball) September 16, 2024
NC State Wolfpack CFB Preview
The NC State Wolfpack enter this game with a 2-1 record and a lot to prove. After a blowout loss to Tennessee, they bounced back with a win over Louisiana Tech. Head coach Dave Doeren knows his team needs to be more disciplined and execute better on both sides of the ball to compete against a Clemson team eager to get back on track. Quarterback Grayson McCall has been the focal point of NC State’s offense, throwing for 476 yards, but the Wolfpack need more from their rushing attack to keep defenses honest. Offensively, NC State has struggled with consistency, averaging 347.3 yards per game. The Wolfpack’s ground game, led by Jordan Waters, has not been as effective as needed, putting additional pressure on McCall to deliver through the air. For NC State to have a chance against Clemson, they must improve their third-down efficiency and sustain longer drives to keep Clemson’s offense off the field. Defensively, the Wolfpack have allowed 30.7 points per game, and their secondary has been particularly susceptible, giving up 244.3 passing yards per game. The defense must tighten up and create turnovers to provide the offense with more opportunities. The key for NC State will be to maintain discipline, especially in the secondary, and avoid giving up big plays that could shift the momentum. Both teams have the talent to win this game, but it will come down to execution and who can control the tempo on both sides of the ball.

Credit: USA TODAY/IMAGN
Clemson Tigers CFB Preview
Clemson Tigers, coming off a 1-1 start, are looking to gain momentum in ACC play after a shaky start to the season. Head coach Dabo Swinney has emphasized the need for more consistency, particularly on defense. The Tigers were dominant in their win over Appalachian State, scoring 66 points, but were exposed by Georgia in a 34-3 loss. The key to Clemson’s success against NC State will be their ability to balance their offensive attack while shoring up a defense that has been vulnerable at times. Cade Klubnik has been solid at quarterback, providing a steady hand and accumulating 520 passing yards with two touchdowns. Clemson’s running game, powered by Phil Mafah, has also been productive, and they will need to continue this trend to control the game against NC State. The Tigers’ offensive line will need to give Klubnik time to make plays and open lanes for the running backs. Defensively, Clemson’s issues have primarily been with their secondary, which has allowed 246 passing yards per game. The Tigers must improve in pass coverage and tackling to avoid giving up big plays that could swing the momentum in NC State’s favor. The defensive line, led by Peter Woods, will also need to apply consistent pressure on NC State’s quarterback to disrupt their passing rhythm.
𝘼𝙣 𝙪𝙣𝙘𝙤𝙢𝙢𝙤𝙣 𝙥𝙧𝙤𝙜𝙧𝙖𝙢, 𝙛𝙧𝙤𝙢 𝙖𝙣 𝙪𝙣𝙘𝙤𝙢𝙢𝙤𝙣 𝙥𝙡𝙖𝙘𝙚.
— Clemson Football (@ClemsonFB) August 30, 2024
It's time to earn it. pic.twitter.com/R5ugDoQvnP
NC State vs. Clemson Prop Picks (AI)
NC State vs. Clemson Prediction (AI)

Remi, our AI sports algorithm, has been pouring over millions of data from every angle between the Wolfpack and Tigers and using recursive machine learning and industry leading AI to crunch the data to a single cover probability.
The Algorithm has been most watching on the trending weight emotional bettors often put on NC State’s strength factors between a Wolfpack team going up against a possibly strong Tigers team. Trends look to say the true game analytics might reflect a strong lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our CFB AI picks for FREE now.
Below is our current AI NC State vs Clemson picks, computer picks Wolfpack vs Tigers, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
---|---|---|---|---|---|---|
CFB | 9/26 | TCU@ARIZST | UNLOCK THIS PICK | 3 |
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|
CFB | 9/26 | FSU@UVA | UNLOCK THIS PICK | 0 |
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full CFB schedule.
Wolfpack Betting Trends
NC State is 0-3 against the spread (ATS) this season. Despite having a winning record, the Wolfpack has struggled to cover the spread in their first three games. Their performances have been inconsistent, particularly on defense, which has allowed 30.7 points per game on average.
Tigers Betting Trends
Clemson is 1-1 ATS this season. The Tigers covered the spread in their dominant 66-20 win over Appalachian State but failed to cover in a loss to Georgia. The team’s performance has been up and down, and they’ll be looking for more consistency against NC State.
Wolfpack vs. Tigers Matchup Trends
Both teams have shown vulnerabilities on defense, with NC State allowing 386 yards per game and Clemson allowing 410.5 yards per game. With both defenses struggling to contain opponents, betting on the over could be an interesting option.
NC State vs. Clemson Game Info
What time does NC State vs Clemson start on September 21, 2024?
NC State vs Clemson starts on September 21, 2024 at 12:00 PM EST.
Where is NC State vs Clemson being played?
Venue: Memorial Stadium.
What are the opening odds for NC State vs Clemson?
Spread: Clemson -17.0
Moneyline: NC State +544, Clemson -794
Over/Under: 48
What are the records for NC State vs Clemson?
NC State: (2-1) | Clemson: (1-1)
What is the AI best bet for NC State vs Clemson?
Remi's is still searching and crunching tons of data to find the perfect prop bet. Stay tuned . . Prices move—always shop for the best number.
What are NC State vs Clemson trending bets?
Both teams have shown vulnerabilities on defense, with NC State allowing 386 yards per game and Clemson allowing 410.5 yards per game. With both defenses struggling to contain opponents, betting on the over could be an interesting option.
What are NC State trending bets?
NCST trend: NC State is 0-3 against the spread (ATS) this season. Despite having a winning record, the Wolfpack has struggled to cover the spread in their first three games. Their performances have been inconsistent, particularly on defense, which has allowed 30.7 points per game on average.
What are Clemson trending bets?
CLEM trend: Clemson is 1-1 ATS this season. The Tigers covered the spread in their dominant 66-20 win over Appalachian State but failed to cover in a loss to Georgia. The team’s performance has been up and down, and they’ll be looking for more consistency against NC State.
Where can I find AI Picks for NC State vs Clemson?
See our latest CFB picks and odds pages for 2024 to compare prices before you bet.
NC State vs. Clemson Odds
Remi is pouring through loads of data on each team. In fact, anytime the NC State vs Clemson trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme altitude rarely follow normal, predictable betting trends.
NC State vs Clemson Opening Odds
NCST Moneyline:
+544 CLEM Moneyline: -794
NCST Spread: +17
CLEM Spread: -17.0
Over/Under: 48
NC State vs Clemson Live Odds
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Western Kentucky Hilltoppers
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+146
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O 56 (-110)
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–
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+146
-170
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+3.5 (-105)
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O 53 (-110)
U 53 (-110)
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BOISE
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–
–
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-750
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-16.5 (-110)
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O 59 (-110)
U 59 (-110)
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Alabama Crimson Tide
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–
–
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+115
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+2.5 (-110)
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O 53.5 (-110)
U 53.5 (-110)
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MIZZOU
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–
–
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-44.5 (-110)
|
O 56.5 (-110)
U 56.5 (-110)
|
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–
–
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+129
-150
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+3 (-110)
-3 (-110)
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O 49.5 (-110)
U 49.5 (-110)
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COLOST
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–
–
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+175
-205
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+5.5 (-110)
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O 49.5 (-110)
U 49.5 (-110)
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Kentucky Wildcats
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UK
SC
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–
–
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+180
-210
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+5.5 (-110)
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O 47.5 (-110)
U 47.5 (-110)
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Marshall Thundering Herd
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UL
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–
–
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-125
+105
|
-2 (-110)
+2 (-110)
|
O 48 (-115)
U 48 (-105)
|
|
Sep 27, 2025 9:00PM EDT
Louisiana Tech Bulldogs
UTEP Miners
9/27/25 9PM
LATECH
UTEP
|
–
–
|
-175
+150
|
-3.5 (-110)
+3.5 (-110)
|
O 48 (-110)
U 48 (-110)
|
|
Sep 27, 2025 10:15PM EDT
BYU Cougars
Colorado Buffaloes
9/27/25 10:15PM
BYU
COLO
|
–
–
|
-235
+200
|
-6.5 (-110)
+6.5 (-110)
|
O 49.5 (-110)
U 49.5 (-110)
|
|
Oct 4, 2025 12:00PM EDT
Minnesota Golden Gophers
Ohio State Buckeyes
10/4/25 12PM
MINN
OHIOST
|
–
–
|
|
+21 (-110)
-21 (-110)
|
|
|
Oct 4, 2025 12:00PM EDT
Kentucky Wildcats
Georgia Bulldogs
10/4/25 12PM
UK
UGA
|
–
–
|
|
+20.5 (-110)
-20.5 (-110)
|
|
|
Oct 4, 2025 12:00PM EDT
Clemson Tigers
North Carolina Tar Heels
10/4/25 12PM
CLEM
UNC
|
–
–
|
-550
+400
|
-13.5 (-110)
+13.5 (-110)
|
O 48.5 (-110)
U 48.5 (-110)
|
|
Oct 4, 2025 12:00PM EDT
Wisconsin Badgers
Michigan Wolverines
10/4/25 12PM
WISC
MICH
|
–
–
|
+580
-880
|
+16.5 (-110)
-16.5 (-110)
|
O 41.5 (-105)
U 41.5 (-115)
|
|
Oct 4, 2025 1:00PM EDT
UTSA Roadrunners
Temple Owls
10/4/25 1PM
UTSA
TEMPLE
|
–
–
|
-210
+172
|
-5.5 (-115)
+5.5 (-105)
|
O 56.5 (-110)
U 56.5 (-110)
|
|
Oct 4, 2025 3:30PM EDT
Vanderbilt Commodores
Alabama Crimson Tide
10/4/25 3:30PM
VANDY
BAMA
|
–
–
|
+360
-480
|
+11.5 (-102)
-11.5 (-120)
|
O 51.5 (-110)
U 51.5 (-110)
|
|
Oct 4, 2025 3:30PM EDT
Washington Huskies
Maryland Terrapins
10/4/25 3:30PM
WASH
MD
|
–
–
|
|
-7 (-110)
+7 (-110)
|
|
|
Oct 4, 2025 3:30PM EDT
Boise State Broncos
Notre Dame Fighting Irish
10/4/25 3:30PM
BOISE
ND
|
–
–
|
+365
-490
|
+15.5 (-110)
-15.5 (-110)
|
O 61.5 (-110)
U 61.5 (-110)
|
|
Oct 4, 2025 3:30PM EDT
Texas Longhorns
Florida Gators
10/4/25 3:30PM
TEXAS
FLA
|
–
–
|
-300
+240
|
-7.5 (-110)
+7.5 (-110)
|
O 46.5 (-110)
U 46.5 (-110)
|
|
Oct 4, 2025 4:00PM EDT
Kent State Golden Flashes
Oklahoma Sooners
10/4/25 4PM
KENT
OKLA
|
–
–
|
|
+45.5 (-110)
-45.5 (-110)
|
O 52.5 (-115)
U 52.5 (-105)
|
|
Oct 4, 2025 4:00PM EDT
Michigan State Spartans
Nebraska Cornhuskers
10/4/25 4PM
MICHST
NEB
|
–
–
|
+360
-480
|
+12.5 (-105)
-12.5 (-115)
|
O 53.5 (-110)
U 53.5 (-110)
|
CFB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers NC State Wolfpack vs. Clemson Tigers on September 21, 2024 at Memorial Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our CFB odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
TULANE@OLEMISS | MISS -11.5 | 54.3% | 4 | WIN |
UNC@UCF | UCF -6.5 | 54.4% | 4 | WIN |
ARKST@KENSAW | KENSAW +4.5 | 54.5% | 4 | WIN |
ILL@IND | IND -6 | 53.2% | 3 | WIN |
SELOU@LSU | LSU -47.5 | 55.3% | 5 | LOSS |
TNMART@MIZZST | MIZZST -14.5 | 56.2% | 6 | WIN |
FRESNO@HAWAII | HAWAII +3 | 56.6% | 6 | WIN |
MRSHL@MTSU | MTSU +2.5 | 56.8% | 6 | LOSS |
MICH@NEB | NEB +1.5 | 57.3% | 7 | LOSS |
WASH@WASHST | DENZEL BOSTON UNDER 69.5 RECV YDS | 56.2% | 6 | LOSS |
IOWA@RUT | ANTWAN RAYMOND OVER 0.5 TOUCHDOWNS | 54.4% | 4 | WIN |
GEORGIA@TENN | UNDER 50.5 | 55.5% | 6 | LOSS |
ARK@OLEMISS | MISS -225 | 72.0% | 9 | WIN |
DUKE@TULANE | TULANE -120 | 56.5% | 4 | WIN |
ARK@OLEMISS | MISS -6.5 | 53.9% | 3 | LOSS |
AKRON@UAB | UAB -11 | 54.7% | 4 | LOSS |
UCONN@DEL | DEL +9.5 | 55.0% | 5 | WIN |
APLST@USM | USM +4 | 55.3% | 6 | WIN |
MERIMK@KENSAW | KENSAW -13.5 | 56.2% | 7 | WIN |
UMASS@IOWA | IOWA -34.5 | 56.4% | 7 | WIN |
UMASS@IOWA | JAZIUN PATTERSON UNDER 0.5 RUSH TDS | 54.8% | 4 | WIN |
NMEX@UCLA | NICO IAMALEAVA UNDER 31.5 PASS ATT | 53.4% | 3 | LOSS |
KSTATE@ARIZ | ARIZ +1.5 | 56.1% | 6 | WIN |
BC@MICHST | NICK MARSH OVER 47.5 RCV YDS | 53.6% | 3 | WIN |
ARIZST@MISSST | MISSST +7 | 54.2% | 4 | WIN |
TULSA@NMEXST | NMEXST +3.5 | 56.9% | 6 | WIN |
UCLA@UNLV | OVER 54.5 | 56.2% | 6 | LOSS |
FRESNO@OREGST | FRESNO +1.5 | 54.7% | 4 | WIN |
VANDY@VATECH | VANDY +2.5 | 55.8% | 5 | WIN |
JMAD@LVILLE | LVILLE -14.5 | 54.0% | 3 | LOSS |
TCU@UNC | JOSEPH MANJACK OVER 37.5 RECV YDS | 53.8% | 3 | LOSS |
ND@MIAMI | MIAMI +3 | 55.2% | 6 | WIN |
MISSST@USM | USM +14.5 | 56.0% | 6 | LOSS |
UTAH@UCLA | UCLA +5.5 | 56.2% | 6 | LOSS |
CAL@OREGST | OREGST +1.5 | 55.1% | 5 | LOSS |
FAU@MD | MD -13.5 | 55.2% | 5 | WIN |
GAS@FRESNO | FRESNO +2 | 55.2% | 5 | WIN |
TOLEDO@UK | UK -9.5 | 56.2% | 6 | LOSS |
AUSTPEAY@MTSU | PEAY +12.5 | 56.2% | 6 | WIN |
LSU@CLEM | GARRETT NUSSMEIER OVER 23.5 PASS COMP | 54.1% | 3 | WIN |
WMICH@MICHST | WMICH +21.5 | 56.2% | 6 | WIN |
ND@OHIOST | WILL HOWARD INTERCEPTIONS OVER 0.5 | 54.80% | 4 | LOSS |
OHIOST@TEXAS | WILL HOWARD PASS + RUSH YDS UNDER 262.5 | 54.70% | 4 | LOSS |
GEORGIA@TEXAS | TEXAS -144 | 54.40% | 4 | LOSS |
AUBURN@BAMA | PAYTON THORNE PASS TDS - UNDER 1.5 | 53.20% | 3 | WIN |
PURDUE@IND | IND -28.5 | 53.90% | 3 | WIN |
FRESNO@UCLA | T.J. HARDEN LONGEST RUSH OVER 17.5 YDS | 54.50% | 4 | LOSS |
TENN@VANDY | VANDY +10.5 | 54.90% | 4 | LOSS |
WVU@TXTECH | TXTECH -2.5 | 54.60% | 4 | WIN |
SC@CLEM | CLEM -130 | 58.70% | 4 | LOSS |
TCU@CINCY | TCU -3 | 54.20% | 4 | WIN |