Arkansas State vs Iowa State Prediction — AI Finds CAN'T MISS CFB Lines & Props (Sep 21)
Updated: 2024-09-14T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The Arkansas State Red Wolves will face the Iowa State Cyclones on September 21, 2024, at Jack Trice Stadium in Ames, IA. Arkansas State is looking to improve on their 1-2 record, while Iowa State, at 2-0, aims to maintain their unbeaten start.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Sep 21, 2024
Start Time: 2:00 PM EST
Venue: Jack Trice Stadium
Cyclones Record: (2-0)
Red Wolves Record: (2-1)
OPENING ODDS
ARKST Moneyline: +987
IOWAST Moneyline: -2000
ARKST Spread: +21.5
IOWAST Spread: -21.5
Over/Under: 51.5
ARKST
Betting Trends
- Arkansas State is 1-2 against the spread (ATS) this season. They covered in a narrow win but failed to cover in their other two matchups, showing inconsistency on both sides of the ball.
IOWAST
Betting Trends
- Iowa State is 1-1 ATS this season. They covered the spread in a blowout win but failed to cover in their other game. The Cyclones have shown strong defensive performances early in the season.
MATCHUP TRENDS
- The over/under for this game is set at 51.5 points. Iowa State has hit the under in one of their two games, while Arkansas State has done so in two of their three games. This trend could suggest a lower-scoring game if both defenses perform as expected.
ARKST vs. IOWAST
Best Prop Bet
- Remi's is still searching and crunching tons of data to find the perfect prop bet. Stay tuned .
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Arkansas State vs Iowa State Prediction & Odds:
Free CFB Betting Insights for 9/21/24
Head coach Matt Campbell has once again built a solid team around a stout defense and a balanced offensive attack. The Cyclones have been particularly effective at controlling the clock and limiting opponents’ scoring opportunities. Quarterback Rocco Becht has managed the offense well, spreading the ball effectively to his playmakers. The Iowa State defense, led by a strong front seven, has been the foundation of their success, applying pressure on opposing quarterbacks and forcing turnovers. To maintain their unbeaten streak, Iowa State will focus on executing their game plan, maintaining discipline on defense, and avoiding costly penalties.
Fought to the end. Final from the Big House.#WolvesUp 🐺🤘🏻 pic.twitter.com/g52gCHSphK
— Arkansas State Football (@AStateFB) September 14, 2024
Arkansas State Red Wolves CFB Preview
The Arkansas State Red Wolves, sitting at 1-2, head into their game against Iowa State looking to turn their season around. Under head coach Butch Jones, the Red Wolves have experienced both highs and lows early in the season. Their offense has struggled to maintain consistency, often being disrupted by turnovers and missed opportunities. Quarterback Jaxon Dailey needs to be more accurate and avoid forced throws against a formidable Iowa State defense. The running game, led by running back Michael Bishop, has shown potential but needs more support from the offensive line to sustain drives. Defensively, Arkansas State has allowed too many explosive plays, especially in the secondary, which could be a significant vulnerability against a balanced Iowa State attack. The key for the Red Wolves will be to avoid turnovers, improve third-down efficiency, and keep the game within reach to have a chance for an upset.

Credit: USA TODAY/IMAGN
Iowa State Cyclones CFB Preview
The Iowa State Cyclones are looking to continue their strong start to the 2024 season as they host Arkansas State. Head coach Matt Campbell has emphasized defense and ball control, which has paid dividends through their first two games. The Cyclones have allowed just 12 points per game, showcasing a defense that is adept at stifling both the run and the pass. Defensive linemen like Will McDonald IV have been critical in providing pressure up front, while the secondary, led by safety Jeremiah Cooper, has been effective in coverage. On offense, quarterback Rocco Becht has done a commendable job managing games, minimizing mistakes, and capitalizing on scoring opportunities. The run game, powered by a combination of a strong offensive line and dynamic backs, adds a balanced dimension to the Cyclones’ attack. Iowa State will aim to continue their disciplined approach, dominate in the trenches, and keep Arkansas State from finding any rhythm on either side of the ball.
Halled it in‼️@BreeceH went up and got it‼️
— Iowa State Football (@CycloneFB) September 15, 2024
📺: #NYJvsTEN on CBS/Paramount+pic.twitter.com/XHDWW5xnTM
Arkansas State vs. Iowa State Prop Picks (AI)
Arkansas State vs. Iowa State Prediction (AI)

Remi, our AI sports genius, has been pouring over exorbitant amounts of data from every facet between the Red Wolves and Cyclones and using recursive machine learning and cutting-edge AI to examine the data to a single cover probability.
Oddly enough, we’ve seen the AI has been most focused on the trending factor knucklehead sportsbettors often put on player performance factors between a Red Wolves team going up against a possibly strong Cyclones team. It appears the true game analytics appear to reflect a moderate lean against one Vegas line specifically.
Unlock this in-depth AI prediction and all of our CFB AI picks for FREE now.
Below is our current AI Arkansas State vs Iowa State picks, computer picks Red Wolves vs Cyclones, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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ACTIVE PICKS LOCKED - SEE NOW |
These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full CFB schedule.
Red Wolves Betting Trends
Arkansas State is 1-2 against the spread (ATS) this season. They covered in a narrow win but failed to cover in their other two matchups, showing inconsistency on both sides of the ball.
Cyclones Betting Trends
Iowa State is 1-1 ATS this season. They covered the spread in a blowout win but failed to cover in their other game. The Cyclones have shown strong defensive performances early in the season.
Red Wolves vs. Cyclones Matchup Trends
The over/under for this game is set at 51.5 points. Iowa State has hit the under in one of their two games, while Arkansas State has done so in two of their three games. This trend could suggest a lower-scoring game if both defenses perform as expected.
Arkansas State vs. Iowa State Game Info
What time does Arkansas State vs Iowa State start on September 21, 2024?
Arkansas State vs Iowa State starts on September 21, 2024 at 2:00 PM EST.
Where is Arkansas State vs Iowa State being played?
Venue: Jack Trice Stadium.
What are the opening odds for Arkansas State vs Iowa State?
Spread: Iowa State -21.5
Moneyline: Arkansas State +987, Iowa State -2000
Over/Under: 51.5
What are the records for Arkansas State vs Iowa State?
Arkansas State: (2-1) | Iowa State: (2-0)
What is the AI best bet for Arkansas State vs Iowa State?
Remi's is still searching and crunching tons of data to find the perfect prop bet. Stay tuned . . Prices move—always shop for the best number.
What are Arkansas State vs Iowa State trending bets?
The over/under for this game is set at 51.5 points. Iowa State has hit the under in one of their two games, while Arkansas State has done so in two of their three games. This trend could suggest a lower-scoring game if both defenses perform as expected.
What are Arkansas State trending bets?
ARKST trend: Arkansas State is 1-2 against the spread (ATS) this season. They covered in a narrow win but failed to cover in their other two matchups, showing inconsistency on both sides of the ball.
What are Iowa State trending bets?
IOWAST trend: Iowa State is 1-1 ATS this season. They covered the spread in a blowout win but failed to cover in their other game. The Cyclones have shown strong defensive performances early in the season.
Where can I find AI Picks for Arkansas State vs Iowa State?
See our latest CFB picks and odds pages for 2024 to compare prices before you bet.
Arkansas State vs. Iowa State Odds
AI algorithm Remi is pouring through tons of stats on each line. In fact, anytime the Arkansas State vs Iowa State trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme travel distance rarely follow normal, predictable betting trends.
Arkansas State vs Iowa State Opening Odds
ARKST Moneyline:
+987 IOWAST Moneyline: -2000
ARKST Spread: +21.5
IOWAST Spread: -21.5
Over/Under: 51.5
Arkansas State vs Iowa State Live Odds
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Ohio Bobcats
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Kansas State Wildcats
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O 57 (-108)
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O 62.5 (-108)
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Illinois Fighting Illini
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+165
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O 55 (-108)
U 55 (-108)
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Oct 25, 2025 3:30PM EDT
Umass Minutemen
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San Diego State Aztecs
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-165
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O 48 (-105)
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Missouri Tigers
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+123
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U 52.5 (-114)
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NC State Wolfpack
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Western Michigan Broncos
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+115
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O 41 (-114)
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UL Monroe Warhawks
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+370
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O 50 (-108)
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Oct 25, 2025 4:00PM EDT
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+3500
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O 56.5 (-103)
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Baylor Bears
Cincinnati Bearcats
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–
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+174
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+5 (-106)
-5 (-106)
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O 67.5 (-108)
U 67.5 (-108)
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Oct 25, 2025 4:15PM EDT
Texas Longhorns
Mississippi State Bulldogs
10/25/25 4:15PM
TEXAS
MISSST
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–
–
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-260
+215
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-7 (-103)
+7 (-109)
|
O 44.5 (-119)
U 44.5 (+102)
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TCU Horned Frogs
West Virginia Mountaineers
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–
–
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-625
+461
|
-15 (-106)
+15 (-106)
|
O 56.5 (-108)
U 56.5 (-108)
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Oct 25, 2025 7:00PM EDT
Wisconsin Badgers
Oregon Ducks
10/25/25 7PM
WISC
OREG
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–
–
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+33.5 (-106)
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|
O 44 (-124)
U 44 (+106)
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Oct 25, 2025 7:00PM EDT
Louisiana Ragin Cajuns
Troy Trojans
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UL
TROY
|
–
–
|
+270
-335
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+9.5 (-106)
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O 47.5 (-108)
U 47.5 (-108)
|
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Oct 25, 2025 7:00PM EDT
Stanford Cardinal
Miami Hurricanes
10/25/25 7PM
STNFRD
MIAMI
|
–
–
|
+3500
-10000
|
+30 (-101)
-30 (-111)
|
O 45 (-113)
U 45 (-104)
|
|
Oct 25, 2025 7:00PM EDT
Georgia Southern Eagles
Arkansas State Red Wolves
10/25/25 7PM
GASO
ARKST
|
–
–
|
+115
-135
|
+2 (-101)
-2 (-111)
|
O 63 (+104)
U 63 (-121)
|
|
Oct 25, 2025 7:30PM EDT
Michigan Wolverines
Michigan State Spartans
10/25/25 7:30PM
MICH
MICHST
|
–
–
|
-600
+446
|
-14 (-101)
+14 (-111)
|
O 48 (-108)
U 48 (-108)
|
|
Oct 25, 2025 7:30PM EDT
Texas A&M Aggies
LSU Tigers
10/25/25 7:30PM
TEXAM
LSU
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–
–
|
-145
+125
|
-2.5 (-116)
+2.5 (+104)
|
O 47.5 (-108)
U 47.5 (-108)
|
|
Oct 25, 2025 7:30PM EDT
Boston College Eagles
Louisville Cardinals
10/25/25 7:30PM
BC
LVILLE
|
–
–
|
+1300
-2500
|
+25.5 (-108)
-25.5 (-104)
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O 55 (-108)
U 55 (-108)
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|
Oct 25, 2025 7:30PM EDT
Colorado State Rams
Wyoming Cowboys
10/25/25 7:30PM
COLOST
WYO
|
–
–
|
+200
-240
|
+6 (+100)
-6 (-112)
|
O 46 (-116)
U 46 (-101)
|
|
Oct 25, 2025 7:45PM EDT
Tennessee Volunteers
Kentucky Wildcats
10/25/25 7:45PM
TENN
UK
|
–
–
|
-350
+280
|
-9.5 (-104)
+9.5 (-108)
|
O 55 (-108)
U 55 (-108)
|
|
Oct 25, 2025 8:00PM EDT
Houston Cougars
Arizona State Sun Devils
10/25/25 8PM
HOU
ARIZST
|
–
–
|
+245
-300
|
+7.5 (-106)
-7.5 (-106)
|
O 47 (-108)
U 47 (-108)
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Oct 25, 2025 10:15PM EDT
Colorado Buffaloes
Utah Utes
10/25/25 10:15PM
COLO
UTAH
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–
–
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+420
-575
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+13.5 (-105)
-13.5 (-115)
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O 50.5 (-110)
U 50.5 (-110)
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CFB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Arkansas State Red Wolves vs. Iowa State Cyclones on September 21, 2024 at Jack Trice Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our CFB odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
FSU@STNFRD | STNFRD +18 | 56.6% | 6 | WIN |
WASHST@UVA | WASHST +17.5 | 58.8% | 8 | WIN |
NEVADA@NMEX | NEVADA +13.5 | 57.8% | 7 | WIN |
TEXAS@UK | ARCH MANNING UNDER 1.5 PASS TD | 56.1% | 6 | WIN |
ARMY@TULANE | ARMY +10 | 55.3% | 5 | WIN |
SJST@UTAHST | SJST +4 | 54.4% | 4 | LOSS |
LVILLE@MIAMI | LVILLE +12.5 | 56.5% | 6 | WIN |
LVILLE@MIAMI | CJ DANIELS UNDER 4.5 RECEPTIONS | 54.4 | 4 | LOSS |
DEL@JAXST | DEL -2.5 | 57.6% | 6 | LOSS |
UTEP@SAMST | UTEP -2.5 | 53.9% | 3 | WIN |
FIU@WKY | FIU +10.5 | 54.6% | 4 | WIN |
ARKST@SALA | ARKST +7.5 | 54.5% | 4 | WIN |
ARKST@SALA | JAYLEN RAYNOR UNDER 40.5 LONGEST PASS COMP | 53.3% | 3 | WIN |
SJST@WYO | SJST -120 | 59.8% | 7 | LOSS |
UMASS@KENTST | KENTST -135 | 60.2% | 6 | WIN |
NOILL@EMICH | EMICH +2.5 | 53.9% | 3 | WIN |
BYU@ARIZ | ARIZ +2.5 | 54.2% | 3 | LOSS |
OKLA@TEXAS | OKLA +2.5 | 54.7% | 4 | LOSS |
NMEX@BOISE | NMEX +16.5 | 56.4% | 6 | WIN |
WAKE@OREGST | WAKE -2.5 | 56.7% | 6 | WIN |
ULMON@COASTAL | ULMON -2.5 | 56.8% | 6 | LOSS |
IOWA@WISC | WISC +4 | 54.8% | 4 | LOSS |
TOLEDO@BGREEN | TOLEDO -10 | 56.3% | 6 | LOSS |
SFLA@NOTEX | SFLA +2.5 | 54.3% | 4 | WIN |
FRESNO@COLOST | RICHIE ANDERSON III LONGEST RECEPTION UNDER 16.5 | 54.4% | 4 | LOSS |
JAXST@SAMST | SAMST +7.5 | 55.3% | 5 | WIN |
USM@GAS | GAS +3.5 | 57.4% | 7 | WIN |
LIB@UTEP | UTEP +2 | 54.5% | 4 | LOSS |
SALA@TROY | SALA -118 | 55.2% | 4 | LOSS |
TULSA@MEMP | MEMP -20.5 | 53.8% | 3 | WIN |
JMAD@GAST | GAST +20.5 | 54.6% | 4 | WIN |
WAKE@VATECH | VATECH -5.5 | 56.6% | 6 | LOSS |
UNLV@WYO | WYO +4.5 | 55.5% | 5 | LOSS |
PSU@UCLA | PSU -24.5 | 56.3% | 6 | LOSS |
TXSTSM@ARKST | TXSTSM -13 | 56.7% | 6 | LOSS |
UVA@LVILLE | ISAAC BROWN OVER 70.5 RUSH YDS | 56.6% | 6 | LOSS |
WVU@BYU | WVU +20.5 | 54.7% | 4 | WIN |
SAMST@NMEXST | SAMST -1.5 | 54.1% | 3 | LOSS |
EMICH@CMICH | CMICH -148 | 62.8% | 7 | WIN |
SDGST@NOILL | SDGST -118 | 55.7% | 3 | WIN |
BAMA@GEORGIA | GEORGIA -125 | 58.7% | 7 | LOSS |
TENN@MISSST | MISSST +7.5 | 54.3% | 4 | WIN |
UK@SC | SC -5.5 | 54.8% | 4 | WIN |
WKY@MIZZST | MIZZST +4.5 | 55.6% | 6 | LOSS |
JAXST@USM | USM -3.5 | 56.0% | 5 | WIN |
NMEXST@NMEX | NMEX -14.5 | 56.9% | 6 | WIN |
ARIZ@IOWAST | ROCCO BECHT UNDER 1.5 PASS TDS | 55.5% | 5 | WIN |
TCU@ARIZST | JOSH HOOVER PASS YDS UNDER 287.5 | 53.4% | 3 | WIN |
ARIZST@BAYLOR | BAYLOR -130 | 58.4% | 6 | LOSS |
WYO@COLO | WYO +13.5 | 54.1% | 3 | LOSS |
TULANE@OLEMISS | MISS -11.5 | 54.3% | 4 | WIN |