Jacksonville State vs Louisville Prediction — AI Finds CAN'T MISS CFB Lines & Props (Sep 07)
Updated: 2024-08-31T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The Jacksonville State Gamecocks will take on the Louisville Cardinals on September 7, 2024, at L&N Federal Credit Union Stadium in Louisville, Kentucky. Louisville is heavily favored by 28 points, reflecting the expectation of a dominant performance from the Cardinals after a strong start to their season.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Sep 07, 2024
Start Time: 3:30 PM EST
Venue: L&N Federal Credit Union Stadium
Cardinals Record: (1-0)
Gamecocks Record: (0-1)
OPENING ODDS
JAXST Moneyline: +1640
LVILLE Moneyline: -5263
JAXST Spread: +28
LVILLE Spread: -28.0
Over/Under: 58
JAXST
Betting Trends
- Jacksonville State is 0-1 against the spread (ATS) this season after a 55-27 loss to Coastal Carolina.
LVILLE
Betting Trends
- Louisville is 1-0 ATS this season, having covered the spread in a commanding 62-0 victory over Austin Peay.
MATCHUP TRENDS
- Louisville must win by more than 28 points to cover the spread against Jacksonville State. Given their dominant showing in the previous game and Jacksonville State’s struggles, Louisville is expected to cover this large spread.
JAXST vs. LVILLE
Best Prop Bet
- Remi searched and crunched the numbers and found a prop for this week's Jacksonville State vs Louisville matchup. Louisville -20 1H ATS play
LIVE CFB ODDS
CFB ODDS COMPARISON
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Jacksonville State vs Louisville Prediction & Odds:
Free CFB Betting Insights for 9/7/24
On the other hand, Jacksonville State faces a tough challenge after a rough 55-27 loss to Coastal Carolina in their first game of the season. The Gamecocks struggled defensively, allowing double-digit points in every quarter and a total of 552 yards. Quarterback Tyler Huff managed 173 passing yards with one touchdown but threw two interceptions. Their rushing game had a brighter spot, with Tre Stewart rushing for 62 yards and a touchdown, but the offense overall struggled to find consistency and protect the ball. The game will likely hinge on whether Jacksonville State can adjust defensively to slow down Louisville’s high-octane offense. Louisville’s defense, which allowed only 106 total yards in their opener, will aim to replicate that performance and capitalize on Jacksonville State’s vulnerabilities. The key for Jacksonville State will be to avoid turnovers and find a way to generate pressure on Shough while finding success in their own offensive drives. However, given the disparity in performances so far, Louisville looks well-positioned to control the game from the outset.
Team Win 👊
— Louisville Football (@LouisvilleFB) September 2, 2024
𝗧𝗵𝗲 𝗖𝗮𝗿𝗱 𝗧𝗮𝗽𝗲: Austin Peay#GoCards pic.twitter.com/4BW3yiu2MV
Jacksonville State Gamecocks CFB Preview
The Jacksonville State Gamecocks are facing a tough road test against a highly ranked Louisville team. After a difficult 55-27 loss to Coastal Carolina, the Gamecocks need to make significant improvements, particularly on defense. Quarterback Tyler Huff will be looking to bounce back from a game where he threw two interceptions, and more focus will be needed to protect the ball and sustain offensive drives. Tre Stewart, who led the rushing effort with 62 yards and a touchdown, will be crucial in providing a balanced attack and keeping the Louisville defense honest. Defensively, Jacksonville State must address the gaps exposed by Coastal Carolina, as they allowed 552 total yards, including 258 through the air. Key defensive adjustments and better execution will be necessary to contain Louisville’s explosive offense and create any chance for an upset. Jacksonville State’s ability to limit big plays and capitalize on turnovers will determine if they can keep the game competitive.

Credit: USA TODAY/IMAGN
Louisville Cardinals CFB Preview
The Louisville Cardinals come into this game with a wave of momentum after a commanding 62-0 win over Austin Peay. Head coach Jeff Brohm has emphasized a balanced offensive approach, and quarterback Tyler Shough’s four-touchdown performance is evidence of that success. Shough’s accuracy and ability to spread the ball around were key in their opening win. The rushing game was equally potent, with Isaac Brown leading all rushers with 123 yards and a touchdown, and it will be a major part of Louisville’s game plan against Jacksonville State. Defensively, the Cardinals allowed only 106 yards and nine first downs, underscoring their strength on that side of the ball. The Cardinals’ strategy will focus on maintaining their offensive efficiency and defensive solidity to secure another dominant win. Playing at home, they will look to leverage their strong start to the season and cover the large spread against a struggling Jacksonville State team.
Team Win 👊
— Louisville Football (@LouisvilleFB) September 2, 2024
𝗧𝗵𝗲 𝗖𝗮𝗿𝗱 𝗧𝗮𝗽𝗲: Austin Peay#GoCards pic.twitter.com/4BW3yiu2MV
Jacksonville State vs. Louisville Prop Picks (AI)
Jacksonville State vs. Louisville Prediction (AI)

Remi, our AI sports genius, has been pouring over mountains of data from every past game between the Gamecocks and Cardinals and using recursive machine learning and industry leading AI to boil down the data to a single cover probability.
Remi has been most keyed in on the trending weight human bettors often put on Jacksonville State’s strength factors between a Gamecocks team going up against a possibly tired Cardinals team. It appears the true game analytics might reflect a moderate lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our CFB AI picks for FREE now.
Below is our current AI Jacksonville State vs Louisville picks, computer picks Gamecocks vs Cardinals, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
---|---|---|---|---|---|---|
ACTIVE PICKS LOCKED - SEE NOW |
These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full CFB schedule.
Gamecocks Betting Trends
Jacksonville State is 0-1 against the spread (ATS) this season after a 55-27 loss to Coastal Carolina.
Cardinals Betting Trends
Louisville is 1-0 ATS this season, having covered the spread in a commanding 62-0 victory over Austin Peay.
Gamecocks vs. Cardinals Matchup Trends
Louisville must win by more than 28 points to cover the spread against Jacksonville State. Given their dominant showing in the previous game and Jacksonville State’s struggles, Louisville is expected to cover this large spread.
Jacksonville State vs. Louisville Game Info
What time does Jacksonville State vs Louisville start on September 07, 2024?
Jacksonville State vs Louisville starts on September 07, 2024 at 3:30 PM EST.
Where is Jacksonville State vs Louisville being played?
Venue: L&N Federal Credit Union Stadium.
What are the opening odds for Jacksonville State vs Louisville?
Spread: Louisville -28.0
Moneyline: Jacksonville State +1640, Louisville -5263
Over/Under: 58
What are the records for Jacksonville State vs Louisville?
Jacksonville State: (0-1) | Louisville: (1-0)
What is the AI best bet for Jacksonville State vs Louisville?
Remi searched and crunched the numbers and found a prop for this week's Jacksonville State vs Louisville matchup. Louisville -20 1H ATS play. Prices move—always shop for the best number.
What are Jacksonville State vs Louisville trending bets?
Louisville must win by more than 28 points to cover the spread against Jacksonville State. Given their dominant showing in the previous game and Jacksonville State’s struggles, Louisville is expected to cover this large spread.
What are Jacksonville State trending bets?
JAXST trend: Jacksonville State is 0-1 against the spread (ATS) this season after a 55-27 loss to Coastal Carolina.
What are Louisville trending bets?
LVILLE trend: Louisville is 1-0 ATS this season, having covered the spread in a commanding 62-0 victory over Austin Peay.
Where can I find AI Picks for Jacksonville State vs Louisville?
See our latest CFB picks and odds pages for 2024 to compare prices before you bet.
Jacksonville State vs. Louisville Odds
Remi is pouring through tons of data points on each player. In fact, anytime the Jacksonville State vs Louisville trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme hostile environments seemingly never follow normal, predictable betting trends.
Jacksonville State vs Louisville Opening Odds
JAXST Moneyline:
+1640 LVILLE Moneyline: -5263
JAXST Spread: +28
LVILLE Spread: -28.0
Over/Under: 58
Jacksonville State vs Louisville Live Odds
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-375
+290
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O 52.5 (-105)
U 52.5 (-115)
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Oct 25, 2025 12:00PM EDT
Bowling Green Falcons
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10/25/25 12PM
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KENT
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-315
+250
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O 48.5 (-110)
U 48.5 (-110)
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Oct 25, 2025 12:00PM EDT
Rutgers Scarlet Knights
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O 59 (-110)
U 59 (-115)
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Oct 25, 2025 12:00PM EDT
South Florida Bulls
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-200
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O 64.5 (-106)
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UCLA Bruins
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O 53.5 (-110)
U 53.5 (-110)
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Northwestern Wildcats
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+225
-280
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O 43.5 (-105)
U 43.5 (-115)
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Oct 25, 2025 12:00PM EDT
Ohio Bobcats
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-450
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-12.5 (-110)
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O 59.5 (-110)
U 59.5 (-110)
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Oct 25, 2025 12:00PM EDT
SMU Mustangs
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O 54.5 (-110)
U 54.5 (-110)
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Oct 25, 2025 12:00PM EDT
Syracuse Orange
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+610
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O 54.5 (-115)
U 54.5 (-105)
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Oct 25, 2025 12:00PM EDT
App State Mountaineers
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Oct 25, 2025 12:00PM EDT
Ole Miss Rebels
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OLEMISS
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O 53.5 (-110)
U 53.5 (-110)
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Oct 25, 2025 12:00PM EDT
Kansas State Wildcats
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O 56.5 (-110)
U 56.5 (-110)
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Oct 25, 2025 12:45PM EDT
Auburn Tigers
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-106
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O 57.5 (-105)
U 57.5 (-115)
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Oct 25, 2025 1:00PM EDT
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UConn Huskies
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O 48.5 (-110)
U 48.5 (-110)
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Oct 25, 2025 3:00PM EDT
Utah State Aggies
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+115
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O 62.5 (-110)
U 62.5 (-110)
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Oct 25, 2025 3:30PM EDT
Minnesota Golden Gophers
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+265
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+8.5 (-110)
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O 38.5 (-112)
U 38.5 (-108)
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Oct 25, 2025 3:30PM EDT
Alabama Crimson Tide
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-465
+350
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O 47.5 (-105)
U 47.5 (-115)
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Oct 25, 2025 3:30PM EDT
BYU Cougars
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Oct 25, 2025 3:30PM EDT
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O 54.5 (-110)
U 54.5 (-110)
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Oct 25, 2025 3:30PM EDT
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+176
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O 41.5 (-110)
U 41.5 (-110)
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Oct 25, 2025 3:30PM EDT
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-105
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O 47.5 (-110)
U 47.5 (-110)
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Oct 25, 2025 3:30PM EDT
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+470
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+15.5 (-110)
-15.5 (-110)
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O 62.5 (-115)
U 62.5 (-105)
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Oct 25, 2025 3:30PM EDT
Illinois Fighting Illini
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ILL
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+146
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O 55.5 (-105)
U 55.5 (-115)
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Oct 25, 2025 3:30PM EDT
Umass Minutemen
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–
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-800
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O 46.5 (-110)
U 46.5 (-110)
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Oct 25, 2025 3:30PM EDT
San Diego State Aztecs
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-152
+126
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O 48.5 (-110)
U 48.5 (-110)
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Oct 25, 2025 3:30PM EDT
Missouri Tigers
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+115
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+2.5 (-106)
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O 51.5 (-114)
U 51.5 (-106)
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Oct 25, 2025 3:30PM EDT
NC State Wolfpack
Pittsburgh Panthers
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NCST
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–
–
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+190
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O 57.5 (-105)
U 57.5 (-115)
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Oct 25, 2025 3:30PM EDT
Western Michigan Broncos
Miami Ohio Redhawks
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+114
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O 41.5 (-110)
U 41.5 (-110)
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Oct 25, 2025 3:30PM EDT
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–
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+340
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+11.5 (-105)
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O 50.5 (-110)
U 50.5 (-110)
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Oct 25, 2025 4:00PM EDT
Oklahoma State Cowboys
Texas Tech Red Raiders
10/25/25 4PM
OKLAST
TXTECH
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–
–
|
+3500
-10000
|
+38.5 (-110)
-38.5 (-110)
|
O 56.5 (-115)
U 56.5 (-105)
|
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Oct 25, 2025 4:00PM EDT
Baylor Bears
Cincinnati Bearcats
10/25/25 4PM
BAYLOR
CINCY
|
–
–
|
+152
-184
|
+4.5 (-115)
-4.5 (-105)
|
O 67.5 (-110)
U 67.5 (-110)
|
|
Oct 25, 2025 4:15PM EDT
Texas Longhorns
Mississippi State Bulldogs
10/25/25 4:15PM
TEXAS
MISSST
|
–
–
|
-285
+230
|
-7.5 (-105)
+7.5 (-115)
|
O 44.5 (-115)
U 44.5 (-105)
|
|
Oct 25, 2025 6:00PM EDT
TCU Horned Frogs
West Virginia Mountaineers
10/25/25 6PM
TCU
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|
–
–
|
-600
+430
|
-14.5 (-110)
+14.5 (-110)
|
O 56.5 (-110)
U 56.5 (-110)
|
|
Oct 25, 2025 7:00PM EDT
Wisconsin Badgers
Oregon Ducks
10/25/25 7PM
WISC
OREG
|
–
–
|
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+34.5 (-115)
-34.5 (-105)
|
O 44.5 (-114)
U 44.5 (-106)
|
|
Oct 25, 2025 7:00PM EDT
Louisiana Ragin Cajuns
Troy Trojans
10/25/25 7PM
UL
TROY
|
–
–
|
+290
-375
|
+9.5 (-105)
-9.5 (-115)
|
O 48.5 (-108)
U 48.5 (-112)
|
|
Oct 25, 2025 7:00PM EDT
Stanford Cardinal
Miami Hurricanes
10/25/25 7PM
STNFRD
MIAMI
|
–
–
|
+3500
-20000
|
+30.5 (-115)
-30.5 (-105)
|
O 45.5 (-104)
U 45.5 (-118)
|
|
Oct 25, 2025 7:00PM EDT
Georgia Southern Eagles
Arkansas State Red Wolves
10/25/25 7PM
GASO
ARKST
|
–
–
|
+105
-126
|
+2.5 (-115)
-2.5 (-105)
|
O 62.5 (-110)
U 62.5 (-110)
|
|
Oct 25, 2025 7:30PM EDT
Michigan Wolverines
Michigan State Spartans
10/25/25 7:30PM
MICH
MICHST
|
–
–
|
-690
+480
|
-13.5 (-120)
+13.5 (-102)
|
O 48.5 (-105)
U 48.5 (-115)
|
|
Oct 25, 2025 7:30PM EDT
Texas A&M Aggies
LSU Tigers
10/25/25 7:30PM
TEXAM
LSU
|
–
–
|
-140
+116
|
-2.5 (-115)
+2.5 (-105)
|
O 48.5 (-104)
U 48.5 (-118)
|
|
Oct 25, 2025 7:30PM EDT
Boston College Eagles
Louisville Cardinals
10/25/25 7:30PM
BC
LVILLE
|
–
–
|
+1400
-4000
|
+25.5 (-110)
-25.5 (-110)
|
O 55.5 (-104)
U 55.5 (-118)
|
|
Oct 25, 2025 7:30PM EDT
Colorado State Rams
Wyoming Cowboys
10/25/25 7:30PM
COLOST
WYO
|
–
–
|
+180
-220
|
+5.5 (-105)
-5.5 (-115)
|
O 46.5 (-110)
U 46.5 (-110)
|
|
Oct 25, 2025 7:45PM EDT
Tennessee Volunteers
Kentucky Wildcats
10/25/25 7:45PM
TENN
UK
|
–
–
|
-345
+265
|
-9.5 (-110)
+9.5 (-110)
|
O 53.5 (-118)
U 53.5 (-104)
|
|
Oct 25, 2025 8:00PM EDT
Houston Cougars
Arizona State Sun Devils
10/25/25 8PM
HOU
ARIZST
|
–
–
|
+245
-310
|
+7.5 (-110)
-7.5 (-110)
|
O 46.5 (-110)
U 46.5 (-110)
|
|
Oct 25, 2025 10:15PM EDT
Colorado Buffaloes
Utah Utes
10/25/25 10:15PM
COLO
UTAH
|
–
–
|
+385
-520
|
+13.5 (-108)
-13.5 (-112)
|
O 49.5 (-115)
U 49.5 (-105)
|
CFB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Jacksonville State Gamecocks vs. Louisville Cardinals on September 07, 2024 at L&N Federal Credit Union Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our CFB odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
FSU@STNFRD | STNFRD +18 | 56.6% | 6 | WIN |
WASHST@UVA | WASHST +17.5 | 58.8% | 8 | WIN |
NEVADA@NMEX | NEVADA +13.5 | 57.8% | 7 | WIN |
TEXAS@UK | ARCH MANNING UNDER 1.5 PASS TD | 56.1% | 6 | WIN |
ARMY@TULANE | ARMY +10 | 55.3% | 5 | WIN |
SJST@UTAHST | SJST +4 | 54.4% | 4 | LOSS |
LVILLE@MIAMI | LVILLE +12.5 | 56.5% | 6 | WIN |
LVILLE@MIAMI | CJ DANIELS UNDER 4.5 RECEPTIONS | 54.4 | 4 | LOSS |
DEL@JAXST | DEL -2.5 | 57.6% | 6 | LOSS |
UTEP@SAMST | UTEP -2.5 | 53.9% | 3 | WIN |
FIU@WKY | FIU +10.5 | 54.6% | 4 | WIN |
ARKST@SALA | ARKST +7.5 | 54.5% | 4 | WIN |
ARKST@SALA | JAYLEN RAYNOR UNDER 40.5 LONGEST PASS COMP | 53.3% | 3 | WIN |
SJST@WYO | SJST -120 | 59.8% | 7 | LOSS |
UMASS@KENTST | KENTST -135 | 60.2% | 6 | WIN |
NOILL@EMICH | EMICH +2.5 | 53.9% | 3 | WIN |
BYU@ARIZ | ARIZ +2.5 | 54.2% | 3 | LOSS |
OKLA@TEXAS | OKLA +2.5 | 54.7% | 4 | LOSS |
NMEX@BOISE | NMEX +16.5 | 56.4% | 6 | WIN |
WAKE@OREGST | WAKE -2.5 | 56.7% | 6 | WIN |
ULMON@COASTAL | ULMON -2.5 | 56.8% | 6 | LOSS |
IOWA@WISC | WISC +4 | 54.8% | 4 | LOSS |
TOLEDO@BGREEN | TOLEDO -10 | 56.3% | 6 | LOSS |
SFLA@NOTEX | SFLA +2.5 | 54.3% | 4 | WIN |
FRESNO@COLOST | RICHIE ANDERSON III LONGEST RECEPTION UNDER 16.5 | 54.4% | 4 | LOSS |
JAXST@SAMST | SAMST +7.5 | 55.3% | 5 | WIN |
USM@GAS | GAS +3.5 | 57.4% | 7 | WIN |
LIB@UTEP | UTEP +2 | 54.5% | 4 | LOSS |
SALA@TROY | SALA -118 | 55.2% | 4 | LOSS |
TULSA@MEMP | MEMP -20.5 | 53.8% | 3 | WIN |
JMAD@GAST | GAST +20.5 | 54.6% | 4 | WIN |
WAKE@VATECH | VATECH -5.5 | 56.6% | 6 | LOSS |
UNLV@WYO | WYO +4.5 | 55.5% | 5 | LOSS |
PSU@UCLA | PSU -24.5 | 56.3% | 6 | LOSS |
TXSTSM@ARKST | TXSTSM -13 | 56.7% | 6 | LOSS |
UVA@LVILLE | ISAAC BROWN OVER 70.5 RUSH YDS | 56.6% | 6 | LOSS |
WVU@BYU | WVU +20.5 | 54.7% | 4 | WIN |
SAMST@NMEXST | SAMST -1.5 | 54.1% | 3 | LOSS |
EMICH@CMICH | CMICH -148 | 62.8% | 7 | WIN |
SDGST@NOILL | SDGST -118 | 55.7% | 3 | WIN |
BAMA@GEORGIA | GEORGIA -125 | 58.7% | 7 | LOSS |
TENN@MISSST | MISSST +7.5 | 54.3% | 4 | WIN |
UK@SC | SC -5.5 | 54.8% | 4 | WIN |
WKY@MIZZST | MIZZST +4.5 | 55.6% | 6 | LOSS |
JAXST@USM | USM -3.5 | 56.0% | 5 | WIN |
NMEXST@NMEX | NMEX -14.5 | 56.9% | 6 | WIN |
ARIZ@IOWAST | ROCCO BECHT UNDER 1.5 PASS TDS | 55.5% | 5 | WIN |
TCU@ARIZST | JOSH HOOVER PASS YDS UNDER 287.5 | 53.4% | 3 | WIN |
ARIZST@BAYLOR | BAYLOR -130 | 58.4% | 6 | LOSS |
WYO@COLO | WYO +13.5 | 54.1% | 3 | LOSS |
TULANE@OLEMISS | MISS -11.5 | 54.3% | 4 | WIN |