Appalachian State vs Clemson Prediction — AI Finds CAN'T MISS CFB Lines & Props (Sep 07)
Updated: 2024-08-31T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The Appalachian State Mountaineers will take on the Clemson Tigers on September 7, 2024, at Memorial Stadium in Clemson, South Carolina. Clemson is a heavy favorite with a -17.5 point spread, reflecting the challenge that Appalachian State faces in this game. Both teams are looking to solidify their early-season form, with Clemson aiming to bounce back after a loss and Appalachian State hoping to continue their winning ways.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Sep 07, 2024
Start Time: 8:00 PM EST
Venue: Memorial Stadium
Tigers Record: (0-1)
Mountaineers Record: (1-0)
OPENING ODDS
APLST Moneyline: +616
CLEM Moneyline: -952
APLST Spread: +17.5
CLEM Spread: -17.5
Over/Under: 52.5
APLST
Betting Trends
- Appalachian State is 0-1 against the spread (ATS) this season, failing to cover in their 38-10 win over East Tennessee State. The Mountaineers have struggled ATS recently, going 6-13-1 in their last 20 games, but have been competitive in non-conference games.
CLEM
Betting Trends
- Clemson is 0-1 ATS this season after losing 34-3 to Georgia. The Tigers are 4-2 ATS in their last six games, but 0-6 ATS in their last six games played in Week 2. Clemson has a strong track record at home, going 18-2 straight up in their last 20 home games.
MATCHUP TRENDS
- Clemson has a notable trend of struggling ATS in Week 2 games, with a 0-6 record in their last six such contests. This could suggest potential vulnerability for Clemson to cover the spread, especially if Appalachian State can execute their game plan effectively and keep the game close.
APLST vs. CLEM
Best Prop Bet
- Remi searched and crunched the numbers and found a prop for this week's App state vs Clemson matchup. QB Joey Aguilar Over 206.5 Passing Yards
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Appalachian State vs Clemson Prediction & Odds:
Free CFB Betting Insights for 9/7/24
On the defensive side, Clemson showed some resilience despite the lopsided score, limiting Georgia to 3.6 yards per play. However, missed tackles and coverage breakdowns allowed Georgia to sustain drives and put the game out of reach. The Tigers will look to re-establish their defensive dominance against an Appalachian State team that poses a different kind of challenge. Appalachian State comes into this matchup with a bit more confidence after a 38-10 win over East Tennessee State. The Mountaineers’ offense, guided by quarterback Ryan Burger, was efficient, particularly through the air, where they averaged 9.1 yards per attempt. The defense also impressed, allowing only 305 total yards and forcing multiple three-and-outs. However, the challenge against Clemson will be significantly tougher, especially at Memorial Stadium. The key for Appalachian State will be to maintain balance on offense and avoid turnovers that could shift momentum. Clemson, meanwhile, needs to get back to basics, establish their ground game, and limit mistakes to avoid giving the Mountaineers any hope of an upset.
APP WINS!
— App State Football (@AppState_FB) August 31, 2024
1-0 #GoApp pic.twitter.com/c7Taegfqqt
Appalachian State Mountaineers CFB Preview
The Appalachian State Mountaineers come into this game as heavy underdogs but with a measure of confidence after their 38-10 win over East Tennessee State. Head coach Shawn Clark will rely on quarterback Ryan Burger, who showed poise in their opener with over 300 passing yards. The ground game, led by Nate Noel, must also be effective to keep Clemson’s defense honest and open up play-action opportunities. Defensively, Appalachian State needs to be aggressive but disciplined. Their secondary, which allowed only 122 passing yards in the opener, will be tested by Clemson’s athletic receivers. Linebackers Trey Cobb and Brendan Harrington will be key in stopping the run and applying pressure on Clemson’s backfield. If Appalachian State can create a few turnovers and keep the game close into the fourth quarter, they could cover the spread or even threaten an upset. Appalachian State’s success will depend on playing mistake-free football and taking advantage of any Clemson miscues. While a victory at Clemson would be a tall task, the Mountaineers are no strangers to playing spoiler against Power Five teams.

Credit: USA TODAY/IMAGN
Clemson Tigers CFB Preview
The Clemson Tigers head into their Week 2 game against Appalachian State with a lot to prove following a disappointing 34-3 loss to Georgia. Head coach Dabo Swinney will need his team to regroup and show the kind of form that has made Clemson a perennial powerhouse. Quarterback Cade Klubnik needs to find his rhythm after a shaky performance where he struggled under pressure. The offensive line will be crucial, as they must provide better protection and create running lanes for backs like Will Shipley, who was largely contained by Georgia’s defense. Defensively, Clemson showed flashes of their potential but were inconsistent. The defensive line, featuring key players like Xavier Thomas and Tyler Davis, needs to dominate the line of scrimmage and disrupt Appalachian State’s backfield. If Clemson’s defense can force turnovers and set up short fields for the offense, it could be a long day for the Mountaineers. Playing at home, where Clemson has an 18-2 record in their last 20 games, the Tigers will aim to use the crowd to their advantage and impose their will on Appalachian State.
Night games in Death Valley >>>
— Clemson Football (@ClemsonFB) September 3, 2024
See you soon Clemson Family. pic.twitter.com/NxpCXoIKSP
Appalachian State vs. Clemson Prop Picks (AI)
Appalachian State vs. Clemson Prediction (AI)

Remi, our AI sports genius, has been pouring over tons of data from every facet between the Mountaineers and Tigers and using recursive machine learning and cutting-edge AI to crunch the data to a single cover probability.
Interestingly enough, the data has been most keyed in on the growing factor human bettors tend to put on coaching factors between a Mountaineers team going up against a possibly healthy Tigers team. Trends look to say the true game analytics appear to reflect a moderate lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our CFB AI picks for FREE now.
Below is our current AI Appalachian State vs Clemson picks, computer picks Mountaineers vs Tigers, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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ACTIVE PICKS LOCKED - SEE NOW |
These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full CFB schedule.
Mountaineers Betting Trends
Appalachian State is 0-1 against the spread (ATS) this season, failing to cover in their 38-10 win over East Tennessee State. The Mountaineers have struggled ATS recently, going 6-13-1 in their last 20 games, but have been competitive in non-conference games.
Tigers Betting Trends
Clemson is 0-1 ATS this season after losing 34-3 to Georgia. The Tigers are 4-2 ATS in their last six games, but 0-6 ATS in their last six games played in Week 2. Clemson has a strong track record at home, going 18-2 straight up in their last 20 home games.
Mountaineers vs. Tigers Matchup Trends
Clemson has a notable trend of struggling ATS in Week 2 games, with a 0-6 record in their last six such contests. This could suggest potential vulnerability for Clemson to cover the spread, especially if Appalachian State can execute their game plan effectively and keep the game close.
Appalachian State vs. Clemson Game Info
What time does Appalachian State vs Clemson start on September 07, 2024?
Appalachian State vs Clemson starts on September 07, 2024 at 8:00 PM EST.
Where is Appalachian State vs Clemson being played?
Venue: Memorial Stadium.
What are the opening odds for Appalachian State vs Clemson?
Spread: Clemson -17.5
Moneyline: Appalachian State +616, Clemson -952
Over/Under: 52.5
What are the records for Appalachian State vs Clemson?
Appalachian State: (1-0) | Clemson: (0-1)
What is the AI best bet for Appalachian State vs Clemson?
Remi searched and crunched the numbers and found a prop for this week's App state vs Clemson matchup. QB Joey Aguilar Over 206.5 Passing Yards. Prices move—always shop for the best number.
What are Appalachian State vs Clemson trending bets?
Clemson has a notable trend of struggling ATS in Week 2 games, with a 0-6 record in their last six such contests. This could suggest potential vulnerability for Clemson to cover the spread, especially if Appalachian State can execute their game plan effectively and keep the game close.
What are Appalachian State trending bets?
APLST trend: Appalachian State is 0-1 against the spread (ATS) this season, failing to cover in their 38-10 win over East Tennessee State. The Mountaineers have struggled ATS recently, going 6-13-1 in their last 20 games, but have been competitive in non-conference games.
What are Clemson trending bets?
CLEM trend: Clemson is 0-1 ATS this season after losing 34-3 to Georgia. The Tigers are 4-2 ATS in their last six games, but 0-6 ATS in their last six games played in Week 2. Clemson has a strong track record at home, going 18-2 straight up in their last 20 home games.
Where can I find AI Picks for Appalachian State vs Clemson?
See our latest CFB picks and odds pages for 2024 to compare prices before you bet.
Appalachian State vs. Clemson Odds
Remi is pouring through loads of data on each player. In fact, anytime the Appalachian State vs Clemson trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme travel distance seemingly never follow normal, predictable patterns.
Appalachian State vs Clemson Opening Odds
APLST Moneyline:
+616 CLEM Moneyline: -952
APLST Spread: +17.5
CLEM Spread: -17.5
Over/Under: 52.5
Appalachian State vs Clemson Live Odds
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O 52 (-110)
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-330
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O 48.5 (-110)
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-140
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U 43.5 (-110)
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Oct 25, 2025 12:00PM EDT
Ohio Bobcats
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-475
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O 59 (-110)
U 59 (-110)
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Oct 25, 2025 12:00PM EDT
SMU Mustangs
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-175
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Oct 25, 2025 12:00PM EDT
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Oct 25, 2025 12:00PM EDT
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O 56.5 (-110)
U 56.5 (-110)
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-105
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O 57 (-110)
U 57 (-110)
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+160
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O 57 (-110)
U 57 (-110)
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–
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+110
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O 41 (-110)
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+355
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+170
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–
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-260
+210
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-7 (-105)
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O 45 (-110)
U 45 (-110)
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–
–
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-650
+460
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-14.5 (-110)
+14.5 (-110)
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O 56.5 (-110)
U 56.5 (-110)
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Oct 25, 2025 7:00PM EDT
Wisconsin Badgers
Oregon Ducks
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OREG
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–
–
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+33.5 (-110)
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O 44.5 (-110)
U 44.5 (-110)
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Louisiana Ragin Cajuns
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UL
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–
–
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+265
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+8.5 (-110)
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O 47.5 (-110)
U 47.5 (-110)
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Oct 25, 2025 7:00PM EDT
Stanford Cardinal
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STNFRD
MIAMI
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–
–
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+2000
-10000
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+30 (-110)
-30 (-110)
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O 45.5 (-110)
U 45.5 (-110)
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Oct 25, 2025 7:00PM EDT
Georgia Southern Eagles
Arkansas State Red Wolves
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ARKST
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–
–
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+115
-140
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+2.5 (-110)
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O 62.5 (-110)
U 62.5 (-110)
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Michigan Wolverines
Michigan State Spartans
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–
–
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-600
+430
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-14 (-110)
+14 (-110)
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O 48 (-110)
U 48 (-110)
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Oct 25, 2025 7:30PM EDT
Texas A&M Aggies
LSU Tigers
10/25/25 7:30PM
TEXAM
LSU
|
–
–
|
-140
+115
|
-2.5 (-115)
+2.5 (-105)
|
O 47.5 (-110)
U 47.5 (-110)
|
|
Oct 25, 2025 7:30PM EDT
Boston College Eagles
Louisville Cardinals
10/25/25 7:30PM
BC
LVILLE
|
–
–
|
+1300
-2500
|
+25.5 (-115)
-25.5 (-105)
|
O 55.5 (-105)
U 55.5 (-115)
|
|
Oct 25, 2025 7:30PM EDT
Colorado State Rams
Wyoming Cowboys
10/25/25 7:30PM
COLOST
WYO
|
–
–
|
+190
-235
|
+6.5 (-115)
-6.5 (-105)
|
O 46.5 (-110)
U 46.5 (-110)
|
|
Oct 25, 2025 7:45PM EDT
Tennessee Volunteers
Kentucky Wildcats
10/25/25 7:45PM
TENN
UK
|
–
–
|
-350
+275
|
-9.5 (-110)
+9.5 (-110)
|
O 54.5 (-110)
U 54.5 (-110)
|
|
Oct 25, 2025 8:00PM EDT
Houston Cougars
Arizona State Sun Devils
10/25/25 8PM
HOU
ARIZST
|
–
–
|
+245
-310
|
+8 (-110)
-8 (-110)
|
O 47 (-110)
U 47 (-110)
|
|
Oct 25, 2025 10:15PM EDT
Colorado Buffaloes
Utah Utes
10/25/25 10:15PM
COLO
UTAH
|
–
–
|
+420
-575
|
+13.5 (-105)
-13.5 (-115)
|
O 50.5 (-110)
U 50.5 (-110)
|
CFB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Appalachian State Mountaineers vs. Clemson Tigers on September 07, 2024 at Memorial Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our CFB odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
FSU@STNFRD | STNFRD +18 | 56.6% | 6 | WIN |
WASHST@UVA | WASHST +17.5 | 58.8% | 8 | WIN |
NEVADA@NMEX | NEVADA +13.5 | 57.8% | 7 | WIN |
TEXAS@UK | ARCH MANNING UNDER 1.5 PASS TD | 56.1% | 6 | WIN |
ARMY@TULANE | ARMY +10 | 55.3% | 5 | WIN |
SJST@UTAHST | SJST +4 | 54.4% | 4 | LOSS |
LVILLE@MIAMI | LVILLE +12.5 | 56.5% | 6 | WIN |
LVILLE@MIAMI | CJ DANIELS UNDER 4.5 RECEPTIONS | 54.4 | 4 | LOSS |
DEL@JAXST | DEL -2.5 | 57.6% | 6 | LOSS |
UTEP@SAMST | UTEP -2.5 | 53.9% | 3 | WIN |
FIU@WKY | FIU +10.5 | 54.6% | 4 | WIN |
ARKST@SALA | ARKST +7.5 | 54.5% | 4 | WIN |
ARKST@SALA | JAYLEN RAYNOR UNDER 40.5 LONGEST PASS COMP | 53.3% | 3 | WIN |
SJST@WYO | SJST -120 | 59.8% | 7 | LOSS |
UMASS@KENTST | KENTST -135 | 60.2% | 6 | WIN |
NOILL@EMICH | EMICH +2.5 | 53.9% | 3 | WIN |
BYU@ARIZ | ARIZ +2.5 | 54.2% | 3 | LOSS |
OKLA@TEXAS | OKLA +2.5 | 54.7% | 4 | LOSS |
NMEX@BOISE | NMEX +16.5 | 56.4% | 6 | WIN |
WAKE@OREGST | WAKE -2.5 | 56.7% | 6 | WIN |
ULMON@COASTAL | ULMON -2.5 | 56.8% | 6 | LOSS |
IOWA@WISC | WISC +4 | 54.8% | 4 | LOSS |
TOLEDO@BGREEN | TOLEDO -10 | 56.3% | 6 | LOSS |
SFLA@NOTEX | SFLA +2.5 | 54.3% | 4 | WIN |
FRESNO@COLOST | RICHIE ANDERSON III LONGEST RECEPTION UNDER 16.5 | 54.4% | 4 | LOSS |
JAXST@SAMST | SAMST +7.5 | 55.3% | 5 | WIN |
USM@GAS | GAS +3.5 | 57.4% | 7 | WIN |
LIB@UTEP | UTEP +2 | 54.5% | 4 | LOSS |
SALA@TROY | SALA -118 | 55.2% | 4 | LOSS |
TULSA@MEMP | MEMP -20.5 | 53.8% | 3 | WIN |
JMAD@GAST | GAST +20.5 | 54.6% | 4 | WIN |
WAKE@VATECH | VATECH -5.5 | 56.6% | 6 | LOSS |
UNLV@WYO | WYO +4.5 | 55.5% | 5 | LOSS |
PSU@UCLA | PSU -24.5 | 56.3% | 6 | LOSS |
TXSTSM@ARKST | TXSTSM -13 | 56.7% | 6 | LOSS |
UVA@LVILLE | ISAAC BROWN OVER 70.5 RUSH YDS | 56.6% | 6 | LOSS |
WVU@BYU | WVU +20.5 | 54.7% | 4 | WIN |
SAMST@NMEXST | SAMST -1.5 | 54.1% | 3 | LOSS |
EMICH@CMICH | CMICH -148 | 62.8% | 7 | WIN |
SDGST@NOILL | SDGST -118 | 55.7% | 3 | WIN |
BAMA@GEORGIA | GEORGIA -125 | 58.7% | 7 | LOSS |
TENN@MISSST | MISSST +7.5 | 54.3% | 4 | WIN |
UK@SC | SC -5.5 | 54.8% | 4 | WIN |
WKY@MIZZST | MIZZST +4.5 | 55.6% | 6 | LOSS |
JAXST@USM | USM -3.5 | 56.0% | 5 | WIN |
NMEXST@NMEX | NMEX -14.5 | 56.9% | 6 | WIN |
ARIZ@IOWAST | ROCCO BECHT UNDER 1.5 PASS TDS | 55.5% | 5 | WIN |
TCU@ARIZST | JOSH HOOVER PASS YDS UNDER 287.5 | 53.4% | 3 | WIN |
ARIZST@BAYLOR | BAYLOR -130 | 58.4% | 6 | LOSS |
WYO@COLO | WYO +13.5 | 54.1% | 3 | LOSS |
TULANE@OLEMISS | MISS -11.5 | 54.3% | 4 | WIN |