Chargers vs Cowboys Prediction — AI Finds CAN'T MISS NFL Lines & Props (Dec 21)
Updated: 2025-12-14T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.
GAME INFO
Date: Dec 21, 2025
Start Time: 1:00 PM EST
Venue:
Cowboys Record:
Chargers Record:
OPENING ODDS
LAC Moneyline:
DAL Moneyline:
LAC Spread: 0
DAL Spread:
Over/Under:
LAC
Betting Trends
DAL
Betting Trends
MATCHUP TRENDS
LAC vs. DAL
Best Prop Bet
LIVE NFL ODDS
NFL ODDS COMPARISON
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Los Angeles vs Dallas Prediction & Odds:
Free NFL Betting Insights for 12/21/25
Los Angeles Chargers NFL Preview
Credit: USA TODAY/IMAGN
Dallas Cowboys NFL Preview
Los Angeles vs. Dallas Prop Picks (AI)
Los Angeles vs. Dallas Prediction (AI)
Remi, our AI sports algorithm, has been pouring over tons of data from every past game between the Chargers and Cowboys and using recursive machine learning and industry leading AI to analyze the data to a single cover probability.
Interestingly enough, the data has been most watching on the trending factor knucklehead sportsbettors regularly put on Los Angeles’s strength factors between a Chargers team going up against a possibly rested Cowboys team. We’ve found the true game analytics appear to reflect a slight lean against one Vegas line specifically.
Unlock this in-depth AI prediction and all of our NFL AI picks for FREE now.
Below is our current AI Los Angeles vs Dallas picks, computer picks Chargers vs Cowboys, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
|---|---|---|---|---|---|---|
| ACTIVE PICKS LOCKED - SEE NOW | ||||||
These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NFL Schedule.
Chargers Betting Trends
Cowboys Betting Trends
Chargers vs. Cowboys Matchup Trends
Los Angeles vs. Dallas Game Info
What time does Los Angeles vs Dallas start on December 21, 2025?
Los Angeles vs Dallas starts on December 21, 2025 at 1:00 PM EST.
What are the opening odds for Los Angeles vs Dallas?
Spread: Dallas
Moneyline: Los Angeles , Dallas
Over/Under:
What are the records for Los Angeles vs Dallas?
Los Angeles: | Dallas:
What is the AI best bet for Los Angeles vs Dallas?
. Prices move—always shop for the best number.
What are Los Angeles trending bets?
LAC trend:
What are Dallas trending bets?
DAL trend:
Where can I find AI Picks for Los Angeles vs Dallas?
See our latest NFL picks and odds pages for 2025 to compare prices before you bet.
Los Angeles vs. Dallas Odds
Remi is pouring through tons of data on each player. In fact, anytime the Los Angeles vs Dallas trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme travel distance seemingly never follow normal, predictable patterns.
Los Angeles vs Dallas Opening Odds
LAC Moneyline:
DAL Moneyline:
LAC Spread: 0
DAL Spread:
Over/Under:
Los Angeles vs Dallas Live Odds
| Games | PTS | ML | SPR | O/U | |
|---|---|---|---|---|---|
|
Oct 23, 2025 8:15PM EDT
Minnesota Vikings
Los Angeles Chargers
10/23/25 8:15PM
Vikings
Chargers
|
–
–
|
+159
-185
|
+3.5 (-115)
-3.5 (-105)
|
O 45 (-110)
U 45 (-110)
|
|
|
Oct 26, 2025 1:00PM EDT
Cleveland Browns
New England Patriots
10/26/25 1PM
Browns
Patriots
|
–
–
|
+290
-360
|
+7 (-110)
-7 (-110)
|
O 40.5 (-110)
U 40.5 (-110)
|
|
|
Oct 26, 2025 1:00PM EDT
Buffalo Bills
Carolina Panthers
10/26/25 1PM
Bills
Panthers
|
–
–
|
-400
+320
|
-7.5 (-105)
+7.5 (-115)
|
O 45.5 (-110)
U 45.5 (-110)
|
|
|
Oct 26, 2025 1:00PM EDT
New York Jets
Cincinnati Bengals
10/26/25 1PM
Jets
Bengals
|
–
–
|
+235
-280
|
+6.5 (-110)
-6.5 (-110)
|
O 44.5 (-105)
U 44.5 (-115)
|
|
|
Oct 26, 2025 1:00PM EDT
Chicago Bears
Baltimore Ravens
10/26/25 1PM
Bears
Ravens
|
–
–
|
+253
-305
|
+7 (-120)
-7 (+100)
|
O 50.5 (-110)
U 50.5 (-110)
|
|
|
Oct 26, 2025 1:00PM EDT
New York Giants
Philadelphia Eagles
10/26/25 1PM
Giants
Eagles
|
–
–
|
+317
-395
|
+7 (-105)
-7 (-115)
|
O 44 (-110)
U 44 (-110)
|
|
|
Oct 26, 2025 1:00PM EDT
San Francisco 49ers
Houston Texans
10/26/25 1PM
49ers
Texans
|
–
–
|
+105
-125
|
+1 (-105)
-1 (-115)
|
O 41.5 (-110)
U 41.5 (-110)
|
|
|
Oct 26, 2025 1:00PM EDT
Miami Dolphins
Atlanta Falcons
10/26/25 1PM
Dolphins
Falcons
|
–
–
|
+280
-350
|
+7 (-110)
-7 (-110)
|
O 44.5 (-110)
U 44.5 (-110)
|
|
|
Oct 26, 2025 4:05PM EDT
Tampa Bay Buccaneers
New Orleans Saints
10/26/25 4:05PM
Buccaneers
Saints
|
–
–
|
-215
+183
|
-4 (-110)
+4 (-110)
|
O 46.5 (-110)
U 46.5 (-110)
|
|
|
Oct 26, 2025 4:25PM EDT
Dallas Cowboys
Denver Broncos
10/26/25 4:25PM
Cowboys
Broncos
|
–
–
|
+146
-170
|
+3.5 (-120)
-3.5 (+100)
|
O 50.5 (-110)
U 50.5 (-110)
|
|
|
Oct 26, 2025 4:25PM EDT
Tennessee Titans
Indianapolis Colts
10/26/25 4:25PM
Titans
Colts
|
–
–
|
+750
-1200
|
+14 (-115)
-14 (-105)
|
O 47 (-110)
U 47 (-110)
|
|
|
Oct 26, 2025 8:20PM EDT
Green Bay Packers
Pittsburgh Steelers
10/26/25 8:20PM
Packers
Steelers
|
–
–
|
-175
+150
|
-3 (-120)
+3 (+100)
|
O 45 (-110)
U 45 (-110)
|
|
|
Oct 27, 2025 8:15PM EDT
Washington Commanders
Kansas City Chiefs
10/27/25 8:15PM
Commanders
Chiefs
|
–
–
|
+465
-630
|
+10.5 (-115)
-10.5 (-105)
|
O 48 (-105)
U 48 (-115)
|
|
|
Oct 30, 2025 8:15PM EDT
Baltimore Ravens
Miami Dolphins
10/30/25 8:15PM
Ravens
Dolphins
|
–
–
|
-430
+340
|
-8 (-110)
+8 (-110)
|
O 50.5 (-110)
U 50.5 (-110)
|
|
|
Nov 2, 2025 1:00PM EST
Chicago Bears
Cincinnati Bengals
11/2/25 1PM
Bears
Bengals
|
–
–
|
-120
+102
|
pk
pk
|
O 49.5 (-110)
U 49.5 (-110)
|
|
|
Nov 2, 2025 1:00PM EST
Indianapolis Colts
Pittsburgh Steelers
11/2/25 1PM
Colts
Steelers
|
–
–
|
-136
+116
|
-2.5 (-110)
+2.5 (-110)
|
O 48.5 (-110)
U 48.5 (-110)
|
NFL Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Los Angeles Chargers vs. Dallas Cowboys on December 21, 2025 at .
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our NFL odds pages, and compare prices before you place a bet.
| NFL |
LEAN | %WIN | UNITS | RESULT |
|---|---|---|---|---|
| TB@DET | RACHAAD WHITE UNDER 14.5 RUSH ATT | 54.4% | 4 | WIN |
| NE@TEN | NE -6.5 | 55.2% | 5 | WIN |
| CAR@NYJ | CAR -110 | 57.4 | 4 | WIN |
| PHI@MIN | PHI -130 | 58.0% | 6 | WIN |
| GB@ARI | ARI +7 | 54.8% | 5 | WIN |
| NO@CHI | NO +4.5 | 57.4% | 7 | LOSS |
| WAS@DAL | JAYDEN DANIELS 1H RUSH YDS OVER 22.5 | 56.1% | 5 | WIN |
| GB@ARI | JORDAN LOVE 1Q PASS YDS OVER 54.5 | 56.6% | 6 | WIN |
| PIT@CIN | JONNU SMITH RECEPTIONS OVER 3.5 | 55.3% | 5 | LOSS |
| BUF@ATL | BUF -3.5 | 54.7% | 4 | LOSS |
| CHI@WAS | JAYDEN DANIELS OVER 1.5 PASS TDS | 56.6% | 6 | WIN |
| TEN@LV | UNDER 42 | 54.8% | 3 | WIN |
| DET@KC | DET +2.5 | 55.7% | 7 | LOSS |
| SEA@JAC | SEA -112 | 55.7% | 5 | WIN |
| LAC@MIA | LAC -3.5 | 54.0% | 3 | LOSS |
| ARI@IND | IND -8.5 | 55.6% | 5 | LOSS |
| TEN@LV | TEN +4.5 | 56.7% | 6 | LOSS |
| LAR@BAL | LAR -7 | 56.2% | 6 | WIN |
| SF@TB | SF +3.5 | 57.2% | 7 | LOSS |
| CLE@PIT | JAYLEN WARREN UNDER 46.5 RUSH YDS | 54.4% | 4 | LOSS |
| DEN@NYJ | BREECE HALL OVER 26.5 RECV YDS | 55.0% | 4 | LOSS |
| KC@JAC | UNDER 45.5 | 54.9% | 3 | LOSS |
| KC@JAC | PATRICK MAHOMES UNDER 23.5 PASS COMP | 56.6% | 6 | LOSS |
| HOU@BAL | HOU -125 | 58.5% | 7 | WIN |
| DET@CIN | DET -10 | 55.6% | 5 | WIN |
| DAL@NYJ | NYJ +1.5 | 53.7% | 3 | LOSS |
| TB@SEA | TB +3.5 | 54.9% | 4 | WIN |
| TEN@ARI | ARI -7 (BUY 0.5) | 54.9% | 4 | LOSS |
| DEN@PHI | DEN +4.5 | 57.5% | 7 | WIN |
| MIA@CAR | TETAIROA MCMILLAN OVER 58.5 RECV YDS | 54.5% | 4 | WIN |
| LV@IND | ASHTON JEANTY UNDER 67.5 RUSH YDS | 54.4% | 4 | WIN |
| SF@LAR | DEMARCUS ROBINSON OVER 29.5 RECV YDS | 55.7% | 5 | WIN |
| NYJ@MIA | NYJ +3 | 53.8 | 3 | LOSS |
| CIN@DEN | DEN -7.5 | 54.8 | 4 | WIN |
| NYJ@MIA | OVER 44 | 52.9% | 2 | WIN |
| CIN@DEN | UNDER 44.5 | 53.7% | 3 | WIN |
| NYJ@MIA | GARRETT WILSON UNDER 9 TARGETS | 53.7% | 3 | WIN |
| CIN@DEN | TEE HIGGINS OVER 6.5 RECV TARGETS | 55.5% | 5 | LOSS |
| WAS@ATL | ATL -2.5 | 54.3 | 4 | WIN |
| BAL@KC | BAL -2.5 | 56.3% | 6 | LOSS |
| TEN@HOU | TEN +7.5 | 57.9% | 7 | LOSS |
| LAC@NYG | LAC -6 | 57.3% | 7 | LOSS |
| NO@BUF | UNDER 48.5 | 55.1% | 3 | LOSS |
| GB@DAL | JAVONTE WILLIAMS UNDER 72.5 RUSH + REC YDS | 55.5% | 5 | LOSS |
| CAR@NE | DRAKE MAYE TO THROW AN INT | 56.6% | 6 | LOSS |
| SEA@ARI | SEA -125 | 57.7% | 6 | WIN |
| SEA@ARI | KYLER MURRAY TO THROW AN INT | 56.6% | 6 | WIN |
| DET@BAL | JAHMYR GIBBS OVER 0.5 RUSH TDS | 55.8% | 5 | WIN |
| DAL@CHI | DAL -120 | 58.7% | 6 | LOSS |
| PIT@NE | PIT -116 | 60.1% | 6 | WIN |
| ATL@CAR | ATL -4.5 | 55.4% | 5 | LOSS |