Giants vs Commanders Prediction — AI Finds CAN'T MISS NFL Lines & Props (Sep 07)

Updated: 2025-08-31T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The New York Giants open the 2025 NFL season on Sunday, September 7 at 1:00 PM ET, taking on the Washington Commanders at Northwest Stadium in Landover, MD. The Commanders enter as 7-point home favorites with an over/under of 45.5 points.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Sep 07, 2025

Start Time: 1:00 PM EST​

Venue: Northwest Stadium​

Commanders Record: (0-0)

Giants Record: (0-0)

OPENING ODDS

NYG Moneyline: +240

WAS Moneyline: -299

NYG Spread: +6.5

WAS Spread: -6.5

Over/Under: 45.5

NYG
Betting Trends

  • The Giants went just 5‑12 against the spread (29.4 %) in 2024 and failed to cover in either head‑to‑head game against Washington last season.

WAS
Betting Trends

  • The Commanders covered an impressive 12‑7‑1 (63.2 %) ATS in 2024 as they surged to the NFC Championship game.

MATCHUP TRENDS

  • Despite Washington’s strong ATS history and dominance over New York last season, the 7‑point opening line reflects both confidence in their growth and skepticism about whether the Giants can stay competitive in divisional road openers.

NYG vs. WAS
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: R. Wilson under 225.5 Passing Yards.

LIVE NFL ODDS

NFL ODDS COMPARISON

WANT MORE AI PICKS?

VAULT
VS. SPREAD
360-272
VAULT
NET UNITS
(INCL VIG & EXEC PKG)
+805.4
VAULT
NET PROFIT
(INCL VIG & EXEC PKG)
$100/UNIT
$80,543
EXECUTIVE
VS. SPREAD
1623-1378
EXECUTIVE
NET UNITS
(INCL VIG)
+408.9
EXECUTIVE
NET PROFIT
(INCL VIG)
$100/UNIT
$40,892

AI SPORTS PICK PRODUCTS

Create a Free Account

‘Create an Account’ to Get Remi’s Picks Today.

Remi Finds New Picks

Remi calculates the probability a team will cover the line.

Remi Works 24/7

Remi uses this probability to assign units to each pick.

Get Remi's AI Picks

Get Remi’s Top AI Sports Picks sent direct to your inbox.

New York vs Washington Prediction & Odds:
Free NFL Betting Insights for 9/7/25

The 2025 NFL season kicks off with a classic NFC East rivalry as the Washington Commanders host the New York Giants on Sunday, September 7, in a matchup that clearly reflects the changing landscape of the division. Washington enters as a 7-point favorite, a fair reflection of the momentum they bring from a 12–5 campaign that saw them reach the NFC Championship Game behind the electrifying play of quarterback Jayden Daniels. The Commanders appear to be a team on the rise, with a retooled offense that now features big-name additions like Deebo Samuel and Laremy Tunsil, along with a defense anchored by veterans such as Bobby Wagner and Von Miller. Meanwhile, the Giants are coming off a disastrous 3–14 season that left more questions than answers, particularly at the quarterback position where veteran Russell Wilson is expected to start while top rookie Jaxson Dart waits in the wings. New York also struggled mightily against the spread last year, finishing with a 5–12 ATS record and failing to cover in either game against Washington. Offensively, the Giants hope rookie wideout Malik Nabers can be a game-changer, but the offensive line remains a major concern, especially against a pass rush as aggressive and disciplined as Washington’s.

The betting total sits around 45.5 points, which suggests a moderate pace and some scoring opportunities, but that may rely more on Washington’s ability to execute than any expectations from New York. Defensively, the Giants have added talent with players like Abdul Carter, but cohesion and experience are lacking, especially in the secondary. For the Commanders, this game presents an opportunity to assert their place at the top of the division and take care of business against a rebuilding rival. If Jayden Daniels can manage the game, extend drives with his legs, and avoid turnovers, Washington should be able to dictate the pace, especially at home. For the Giants to cover or pull off a shocking upset, they’ll need to win the turnover battle, control the clock with efficient short-yardage plays, and find ways to generate points from special teams or defensive stands. History, recent form, and roster composition all point toward a commanding Washington win, but Week 1 games have a tendency to surprise—especially when desperation meets opportunity. However, given how both teams trended last season, anything short of a dominant performance by Washington would be seen as a missed opportunity. The Commanders have the edge in quarterback play, pass protection, pass rush, and overall cohesion, while the Giants are leaning on hope, new faces, and a best-case-scenario performance just to stay competitive. The narrative entering this game is clear: Washington is ready to contend, while the Giants are hoping to prove they still belong.

New York Giants NFL Preview

The New York Giants enter the 2025 season with low expectations after a brutal 3–14 campaign that saw them finish with one of the worst records and worst against-the-spread marks in the league. Their 5–12 ATS record from last year reflects a team that consistently underperformed and struggled to stay competitive, particularly in divisional matchups where they failed to cover in either game against the Commanders. The offseason offered a chance to hit the reset button, and the organization attempted to do so by drafting quarterback Jaxson Dart and signing veterans Russell Wilson and Jameis Winston to bridge the gap under center. For now, Wilson is expected to start Week 1, though he will be operating behind an offensive line that remains one of the most unstable in the league. There is optimism surrounding wide receiver Malik Nabers, who showed elite explosiveness in preseason and has already emerged as the top target in the passing game, while tight end Darren Waller offers a reliable presence over the middle. Saquon Barkley’s departure has left the run game in the hands of a committee, which could present early inefficiencies against a defense like Washington’s that excels at clogging the box and collapsing lanes. On defense, rookie pass rusher Abdul Carter adds speed and power off the edge, but the secondary lacks depth and could struggle to keep pace with Washington’s wideouts.

The Giants must also overcome their recent history at FedEx Field, where they’ve struggled to generate consistent offense and frequently fell behind early, putting pressure on a passing attack that lacks rhythm. If New York hopes to stay competitive or cover the spread, it will require a near-perfect performance from Wilson, mistake-free football, and opportunistic defense that can turn takeaways into points. Head coach Brian Daboll enters a critical year, with questions about whether his 2022 playoff run was a fluke or a glimpse of unrealized potential. The offensive playcalling must be more aggressive but also calculated to keep pressure off the quarterback and shorten the game. Defensively, stopping Jayden Daniels from extending plays and controlling the clock will be paramount, as Washington’s offense thrives on tempo and spacing. The Giants will need to win situational downs—third downs, red zone, and two-minute drills—to have any chance of success. Special teams may be the hidden X-factor, with the Giants needing to flip the field and generate momentum from return opportunities or key punts. Still, based on recent history, personnel matchups, and form, the Giants face an uphill battle on the road in Week 1, and while it’s not impossible for them to keep things close, they must be near flawless in execution to do so. In what’s shaping up to be a tough year for New York, this opener against a surging division rival will be an early test of both resolve and direction.

The New York Giants open the 2025 NFL season on Sunday, September 7 at 1:00 PM ET, taking on the Washington Commanders at Northwest Stadium in Landover, MD. The Commanders enter as 7-point home favorites with an over/under of 45.5 points. New York vs Washington AI Prediction: Free NFL Betting Insights for Sep 07. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Washington Commanders NFL Preview

The Washington Commanders enter the 2025 NFL season with a wave of momentum and a rare sense of stability as they open Week 1 at home against the division rival New York Giants. After a breakout 12–5 campaign that culminated in an NFC Championship Game appearance, Washington has become one of the league’s most intriguing young contenders, led by the electric Jayden Daniels at quarterback. Daniels returns after a sensational rookie season in which he accounted for over 4,400 total yards and 32 touchdowns, displaying poise, explosiveness, and leadership well beyond his years. The offseason only added more firepower to this roster, as the Commanders acquired All-Pro wideout Deebo Samuel to pair with Terry McLaurin and also fortified the offensive line by signing Laremy Tunsil to protect Daniels’ blind side. On defense, head coach Dan Quinn has rebuilt the front seven into a fast, physical unit anchored by Bobby Wagner, Von Miller, and a disruptive defensive line that’s expected to give the Giants’ offense major problems. Washington’s defensive success last year—especially in forcing turnovers and shutting down third downs—translated into a stellar 12–7–1 record against the spread, and they covered easily in both games against the Giants, including a dominant win at home. Entering this matchup as 7-point favorites, the Commanders will look to assert themselves early, taking advantage of a New York team still trying to find its identity and break in new personnel, including at quarterback.

Daniels’ mobility will be especially dangerous against a Giants defense that struggled to contain dual-threat quarterbacks last year, and with McLaurin, Samuel, and tight end Logan Thomas creating mismatches downfield, Washington’s offense should find plenty of opportunities. The run game will also play a pivotal role, with the addition of Austin Ekeler giving the Commanders a dynamic backfield option who excels as both a rusher and receiver. Defensively, Washington will likely deploy a variety of looks to confuse Russell Wilson, challenge a shaky Giants offensive line, and pressure him into mistakes. The home crowd at FedEx Field will be fired up to kick off what is shaping up to be a promising season, and the Commanders have all the tools to deliver a statement performance in their opener. Special teams have also improved, with kicker Brandon McManus and punter Tress Way giving the team dependable veterans in key field position situations. The coaching staff, now in its second full year with Quinn at the helm, brings continuity and a clearer identity on both sides of the ball. If Washington sticks to its formula—ball control, pressure defense, and explosive vertical plays—they should not only win but also cover the spread convincingly. This game presents an ideal setting for the Commanders to reinforce their status as legitimate NFC contenders and set the tone for what they hope will be a deep playoff push. The expectations are real, the talent is in place, and now it’s time for Washington to deliver—starting with a commanding performance against a struggling divisional foe.

New York vs. Washington Prop Picks (AI)

AI algorithm Remi is pouring through mountains of data on each team. In fact, anytime the Giants and Commanders play there’s always several intriguing trends to key in on. Not to mention games played at Northwest Stadium in Sep almost always follow normal, predictable patterns.
Remi's searched hard and found the best prop for this matchup: R. Wilson under 225.5 Passing Yards.

New York vs. Washington Prediction (AI)

Remi Robot Icon

Remi, our AI sports algorithm, has been pouring over millions of data from every past game between the Giants and Commanders and using recursive machine learning and industry leading AI to crunch the data to a single cover probability.

The Algorithm has been most keyed in on the unproportionally assigned factor human bettors tend to put on player performance factors between a Giants team going up against a possibly improved Commanders team. It appears the true game analytics might reflect a moderate lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our NFL AI picks for FREE now.

Below is our current AI New York vs Washington picks, computer picks Giants vs Commanders, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
NFL 11/20 BUF@HOU UNLOCK THIS PICK 6 VAULT v3 Locked VAULT v3
NFL 11/20 BUF@HOU UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
NFL 11/20 BUF@HOU UNLOCK THIS PICK 1 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NFL Schedule.

Giants Betting Trends

The Giants went just 5‑12 against the spread (29.4 %) in 2024 and failed to cover in either head‑to‑head game against Washington last season.

Commanders Betting Trends

The Commanders covered an impressive 12‑7‑1 (63.2 %) ATS in 2024 as they surged to the NFC Championship game.

Giants vs. Commanders Matchup Trends

Despite Washington’s strong ATS history and dominance over New York last season, the 7‑point opening line reflects both confidence in their growth and skepticism about whether the Giants can stay competitive in divisional road openers.

New York vs. Washington Game Info

New York vs Washington starts on September 07, 2025 at 1:00 PM EST.

Spread: Washington -6.5
Moneyline: New York +240, Washington -299
Over/Under: 45.5

New York: (0-0)  |  Washington: (0-0)

Remi's searched hard and found the best prop for this matchup: R. Wilson under 225.5 Passing Yards.. Prices move—always shop for the best number.

Despite Washington’s strong ATS history and dominance over New York last season, the 7‑point opening line reflects both confidence in their growth and skepticism about whether the Giants can stay competitive in divisional road openers.

NYG trend: The Giants went just 5‑12 against the spread (29.4 %) in 2024 and failed to cover in either head‑to‑head game against Washington last season.

WAS trend: The Commanders covered an impressive 12‑7‑1 (63.2 %) ATS in 2024 as they surged to the NFC Championship game.

See our latest NFL picks and odds pages for 2025 to compare prices before you bet.

New York vs. Washington Odds

Remi is pouring through loads of data points on each team. In fact, anytime the New York vs Washington trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme travel distance can often follow normal, predictable betting trends.

New York vs Washington Opening Odds

NYG Moneyline: +240
WAS Moneyline: -299
NYG Spread: +6.5
WAS Spread: -6.5
Over/Under: 45.5

New York vs Washington Live Odds

Games PTS ML SPR O/U
Nov 23, 2025 1:00PM EST
Seattle Seahawks
Tennessee Titans
11/23/25 1PM
Seahawks
Titans
-1100
+700
-13.5 (-104)
+13.5 (-118)
O 40.5 (-108)
U 40.5 (-112)
Nov 23, 2025 1:00PM EST
New England Patriots
Cincinnati Bengals
11/23/25 1PM
Patriots
Bengals
-280
+230
-5.5 (-114)
+5.5 (-106)
O 51.5 (-105)
U 51.5 (-115)
Nov 23, 2025 1:00PM EST
New York Giants
Detroit Lions
11/23/25 1PM
Giants
Lions
+480
-650
+10.5 (-120)
-10.5 (-102)
O 49.5 (-115)
U 49.5 (-105)
Nov 23, 2025 1:00PM EST
New York Jets
Baltimore Ravens
11/23/25 1PM
Jets
Ravens
+870
-1500
+13.5 (-106)
-13.5 (-114)
O 44.5 (-110)
U 44.5 (-110)
Nov 23, 2025 1:00PM EST
Indianapolis Colts
Kansas City Chiefs
11/23/25 1PM
Colts
Chiefs
+156
-186
+3.5 (-118)
-3.5 (-104)
O 49.5 (-115)
U 49.5 (-105)
Nov 23, 2025 1:00PM EST
Minnesota Vikings
Green Bay Packers
11/23/25 1PM
Vikings
Packers
+250
-310
+6.5 (-110)
-6.5 (-110)
O 41.5 (-105)
U 41.5 (-115)
Nov 23, 2025 1:00PM EST
Pittsburgh Steelers
Chicago Bears
11/23/25 1PM
Steelers
Bears
+120
-142
+2.5 (-105)
-2.5 (-115)
O 44.5 (-120)
U 44.5 (-102)
Nov 23, 2025 4:05PM EST
Cleveland Browns
Las Vegas Raiders
11/23/25 4:05PM
Browns
Raiders
+168
-200
+3.5 (-104)
-3.5 (-118)
O 36.5 (-104)
U 36.5 (-118)
Nov 23, 2025 4:05PM EST
Jacksonville Jaguars
Arizona Cardinals
11/23/25 4:05PM
Jaguars
Cardinals
-158
+134
-2.5 (-122)
+2.5 (+100)
O 47.5 (-105)
U 47.5 (-115)
Nov 23, 2025 4:25PM EST
Philadelphia Eagles
Dallas Cowboys
11/23/25 4:25PM
Eagles
Cowboys
-176
+148
-3.5 (+100)
+3.5 (-122)
O 47.5 (-115)
U 47.5 (-105)
Nov 23, 2025 4:25PM EST
Atlanta Falcons
New Orleans Saints
11/23/25 4:25PM
Falcons
Saints
+114
-134
+1.5 (-108)
-1.5 (-112)
O 39.5 (-115)
U 39.5 (-105)
Nov 23, 2025 8:20PM EST
Tampa Bay Buccaneers
Los Angeles Rams
11/23/25 8:20PM
Buccaneers
Rams
+260
-320
+6.5 (-104)
-6.5 (-118)
O 49.5 (-110)
U 49.5 (-110)
Nov 24, 2025 8:15PM EST
Carolina Panthers
San Francisco 49ers
11/24/25 8:15PM
Panthers
49ers
+295
-370
+7 (-110)
-7 (-110)
O 49.5 (-105)
U 49.5 (-115)
Nov 27, 2025 1:00PM EST
Green Bay Packers
Detroit Lions
11/27/25 1PM
Packers
Lions
+138
-164
+3 (-110)
-3 (-110)
O 48.5 (-120)
U 48.5 (-102)
Nov 27, 2025 4:30PM EST
Kansas City Chiefs
Dallas Cowboys
11/27/25 4:30PM
Chiefs
Cowboys
-186
+156
-3.5 (-110)
+3.5 (-110)
O 51.5 (-110)
U 51.5 (-110)
Nov 27, 2025 8:20PM EST
Cincinnati Bengals
Baltimore Ravens
11/27/25 8:20PM
Bengals
Ravens
+320
-410
+6.5 (-105)
-6.5 (-115)
O 53 (-110)
U 53 (-110)

NFL Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers New York Giants vs. Washington Commanders on September 07, 2025 at Northwest Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our NFL odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
DAL@LV UNDER 49.5 54.3% 3 WIN
DAL@LV BROCK BOWERS OVER 6.5 RECEPTIONS 57.6% 7 WIN
CAR@ATL BRYCE YOUNG UNDER 0.5 INT 56.1% 6 WIN
KC@DEN PATRICK MAHOMES UNDER 266.5 PASS YDS 55.3% 5 LOSS
SF@ARI SF -3 56.4% 6 WIN
GB@NYG GB -7 54.3% 4 PUSH
LAC@JAC LAC -3 53.2% 3 LOSS
SEA@LAR SEA +3.5 57.2% 7 WIN
CHI@MIN MIN -2.5 53.4% 2 LOSS
DET@PHI DET +3 55.8% 5 LOSS
KC@DEN DEN +4.5 53.0% 2 WIN
DET@PHI UNDER 47 53.4% 2 WIN
SEA@LAR OVER 48.5 54.6% 4 LOSS
NYJ@NE UNDER 43.5 53.4% 3 WIN
NYJ@NE JAMIEN SHERWOOD OVER 4.5 TACKLES 56.8% 6 LOSS
PHI@GB PHI +1.5 54.8% 4 WIN
PHI@GB UNDER 45.5 52.4% 2 WIN
PHI@GB SAQUON BARKLEY OVER 17.5 RUSH ATT 56.6% 6 WIN
PHI@GB JOSH JACOBS UNDER 42.5 1ST HALF RUSH + REC YDS 54.4% 4 LOSS
NO@CAR CAR -5 55.4% 5 LOSS
BAL@MIN BAL -3.5 57.6% 7 WIN
CLE@NYJ CLE -130 65.4% 7 LOSS
NYG@CHI CHI -4.5 55.2% 5 LOSS
NE@TB TB -2 56.1% 6 LOSS
LAR@SF LAR -5.5 53.3% 2 WIN
JAC@HOU UNDER 38 54.8% 5 LOSS
ARI@SEA TREY MCBRIDE OVER 9 RECV TARGETS 55.8% 5 WIN
DET@WAS TERRION ARNOLD OVER 4.5 TACKLES + ASSTS 56.8% 6 LOSS
JAC@HOU TRAVIS ETIENNE UNDER 74.5 RUSH + REC YDS 54.4 4 LOSS
LV@DEN DANIEL CARLSON OVER 1.5 FIELD GOALS 55.2% 5 LOSS
LV@DEN COURTLAND SUTTON OVER 53.5 RECV YDS 54.2% 4 LOSS
LV@DEN RILEY MOSS OVER 4.5 TACKLE + ASST 54.8% 4 WIN
LV@DEN UNDER 43 53.4% 2 WIN
ARI@DAL BUDDA BAKER OVER 7.5 TACKLES + ASSTS 54.4% 4 WIN
ARI@DAL GEORGE PICKENS OVER 4.5 RECEPTIONS 56.6% 6 WIN
DEN@HOU WIL LUTZ OVER 1.5 MADE FIELD GOALS 54.2% 3 LOSS
SEA@WAS SEA -3 56.7% 6 WIN
IND@PIT IND -3 56.8% 6 LOSS
LAC@TEN LAC -9.5 56.2% 6 LOSS
CHI@CIN CHI -2.5 52.6% 2 WIN
SEA@WAS OVER 48 52.9% 2 WIN
SEA@WAS JAYDEN DANIELS OVER 20.5 PASS COMP 56.7% 6 LOSS
JAC@LV JAC -140 64.2% 7 WIN
NO@LAR LAR -14 55.0% 4 WIN
DEN@HOU HOU -1.5 54.2% 3 LOSS
CAR@GB GB -12.5 55.4% 5 LOSS
SF@NYG NYG +2.5 56.1% 5 LOSS
BAL@MIA TUA TAGOVAILOA UNDER 0.5 INT 55.3% 5 LOSS
TB@NO TB -3.5 52.3% 1 WIN
GB@PIT GB -2.5 52.3% 1 WIN
SF@HOU SF +2.5 56.0% 6 LOSS