Giants vs. Commanders
Prediction, Odds & Props
Sep 07 | NFL AI Picks

Updated: 2025-08-31T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The New York Giants open the 2025 NFL season on Sunday, September 7 at 1:00 PM ET, taking on the Washington Commanders at Northwest Stadium in Landover, MD. The Commanders enter as 7-point home favorites with an over/under of 45.5 points.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Sep 07, 2025

Start Time: 1:00 PM EST​

Venue: Northwest Stadium​

Commanders Record: (0-0)

Giants Record: (0-0)

OPENING ODDS

NYG Moneyline: +240

WAS Moneyline: -299

NYG Spread: +6.5

WAS Spread: -6.5

Over/Under: 45.5

NYG
Betting Trends

  • The Giants went just 5‑12 against the spread (29.4 %) in 2024 and failed to cover in either head‑to‑head game against Washington last season.

WAS
Betting Trends

  • The Commanders covered an impressive 12‑7‑1 (63.2 %) ATS in 2024 as they surged to the NFC Championship game.

MATCHUP TRENDS

  • Despite Washington’s strong ATS history and dominance over New York last season, the 7‑point opening line reflects both confidence in their growth and skepticism about whether the Giants can stay competitive in divisional road openers.

NYG vs. WAS
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: R. Wilson under 225.5 Passing Yards.

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New York vs Washington Prediction & Odds:
Free NFL Betting Insights for 9/7/25

The 2025 NFL season kicks off with a classic NFC East rivalry as the Washington Commanders host the New York Giants on Sunday, September 7, in a matchup that clearly reflects the changing landscape of the division. Washington enters as a 7-point favorite, a fair reflection of the momentum they bring from a 12–5 campaign that saw them reach the NFC Championship Game behind the electrifying play of quarterback Jayden Daniels. The Commanders appear to be a team on the rise, with a retooled offense that now features big-name additions like Deebo Samuel and Laremy Tunsil, along with a defense anchored by veterans such as Bobby Wagner and Von Miller. Meanwhile, the Giants are coming off a disastrous 3–14 season that left more questions than answers, particularly at the quarterback position where veteran Russell Wilson is expected to start while top rookie Jaxson Dart waits in the wings. New York also struggled mightily against the spread last year, finishing with a 5–12 ATS record and failing to cover in either game against Washington. Offensively, the Giants hope rookie wideout Malik Nabers can be a game-changer, but the offensive line remains a major concern, especially against a pass rush as aggressive and disciplined as Washington’s.

The betting total sits around 45.5 points, which suggests a moderate pace and some scoring opportunities, but that may rely more on Washington’s ability to execute than any expectations from New York. Defensively, the Giants have added talent with players like Abdul Carter, but cohesion and experience are lacking, especially in the secondary. For the Commanders, this game presents an opportunity to assert their place at the top of the division and take care of business against a rebuilding rival. If Jayden Daniels can manage the game, extend drives with his legs, and avoid turnovers, Washington should be able to dictate the pace, especially at home. For the Giants to cover or pull off a shocking upset, they’ll need to win the turnover battle, control the clock with efficient short-yardage plays, and find ways to generate points from special teams or defensive stands. History, recent form, and roster composition all point toward a commanding Washington win, but Week 1 games have a tendency to surprise—especially when desperation meets opportunity. However, given how both teams trended last season, anything short of a dominant performance by Washington would be seen as a missed opportunity. The Commanders have the edge in quarterback play, pass protection, pass rush, and overall cohesion, while the Giants are leaning on hope, new faces, and a best-case-scenario performance just to stay competitive. The narrative entering this game is clear: Washington is ready to contend, while the Giants are hoping to prove they still belong.

New York Giants NFL Preview

The New York Giants enter the 2025 season with low expectations after a brutal 3–14 campaign that saw them finish with one of the worst records and worst against-the-spread marks in the league. Their 5–12 ATS record from last year reflects a team that consistently underperformed and struggled to stay competitive, particularly in divisional matchups where they failed to cover in either game against the Commanders. The offseason offered a chance to hit the reset button, and the organization attempted to do so by drafting quarterback Jaxson Dart and signing veterans Russell Wilson and Jameis Winston to bridge the gap under center. For now, Wilson is expected to start Week 1, though he will be operating behind an offensive line that remains one of the most unstable in the league. There is optimism surrounding wide receiver Malik Nabers, who showed elite explosiveness in preseason and has already emerged as the top target in the passing game, while tight end Darren Waller offers a reliable presence over the middle. Saquon Barkley’s departure has left the run game in the hands of a committee, which could present early inefficiencies against a defense like Washington’s that excels at clogging the box and collapsing lanes. On defense, rookie pass rusher Abdul Carter adds speed and power off the edge, but the secondary lacks depth and could struggle to keep pace with Washington’s wideouts.

The Giants must also overcome their recent history at FedEx Field, where they’ve struggled to generate consistent offense and frequently fell behind early, putting pressure on a passing attack that lacks rhythm. If New York hopes to stay competitive or cover the spread, it will require a near-perfect performance from Wilson, mistake-free football, and opportunistic defense that can turn takeaways into points. Head coach Brian Daboll enters a critical year, with questions about whether his 2022 playoff run was a fluke or a glimpse of unrealized potential. The offensive playcalling must be more aggressive but also calculated to keep pressure off the quarterback and shorten the game. Defensively, stopping Jayden Daniels from extending plays and controlling the clock will be paramount, as Washington’s offense thrives on tempo and spacing. The Giants will need to win situational downs—third downs, red zone, and two-minute drills—to have any chance of success. Special teams may be the hidden X-factor, with the Giants needing to flip the field and generate momentum from return opportunities or key punts. Still, based on recent history, personnel matchups, and form, the Giants face an uphill battle on the road in Week 1, and while it’s not impossible for them to keep things close, they must be near flawless in execution to do so. In what’s shaping up to be a tough year for New York, this opener against a surging division rival will be an early test of both resolve and direction.

The New York Giants open the 2025 NFL season on Sunday, September 7 at 1:00 PM ET, taking on the Washington Commanders at Northwest Stadium in Landover, MD. The Commanders enter as 7-point home favorites with an over/under of 45.5 points. New York vs Washington AI Prediction: Free NFL Betting Insights for Sep 07. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Washington Commanders NFL Preview

The Washington Commanders enter the 2025 NFL season with a wave of momentum and a rare sense of stability as they open Week 1 at home against the division rival New York Giants. After a breakout 12–5 campaign that culminated in an NFC Championship Game appearance, Washington has become one of the league’s most intriguing young contenders, led by the electric Jayden Daniels at quarterback. Daniels returns after a sensational rookie season in which he accounted for over 4,400 total yards and 32 touchdowns, displaying poise, explosiveness, and leadership well beyond his years. The offseason only added more firepower to this roster, as the Commanders acquired All-Pro wideout Deebo Samuel to pair with Terry McLaurin and also fortified the offensive line by signing Laremy Tunsil to protect Daniels’ blind side. On defense, head coach Dan Quinn has rebuilt the front seven into a fast, physical unit anchored by Bobby Wagner, Von Miller, and a disruptive defensive line that’s expected to give the Giants’ offense major problems. Washington’s defensive success last year—especially in forcing turnovers and shutting down third downs—translated into a stellar 12–7–1 record against the spread, and they covered easily in both games against the Giants, including a dominant win at home. Entering this matchup as 7-point favorites, the Commanders will look to assert themselves early, taking advantage of a New York team still trying to find its identity and break in new personnel, including at quarterback.

Daniels’ mobility will be especially dangerous against a Giants defense that struggled to contain dual-threat quarterbacks last year, and with McLaurin, Samuel, and tight end Logan Thomas creating mismatches downfield, Washington’s offense should find plenty of opportunities. The run game will also play a pivotal role, with the addition of Austin Ekeler giving the Commanders a dynamic backfield option who excels as both a rusher and receiver. Defensively, Washington will likely deploy a variety of looks to confuse Russell Wilson, challenge a shaky Giants offensive line, and pressure him into mistakes. The home crowd at FedEx Field will be fired up to kick off what is shaping up to be a promising season, and the Commanders have all the tools to deliver a statement performance in their opener. Special teams have also improved, with kicker Brandon McManus and punter Tress Way giving the team dependable veterans in key field position situations. The coaching staff, now in its second full year with Quinn at the helm, brings continuity and a clearer identity on both sides of the ball. If Washington sticks to its formula—ball control, pressure defense, and explosive vertical plays—they should not only win but also cover the spread convincingly. This game presents an ideal setting for the Commanders to reinforce their status as legitimate NFC contenders and set the tone for what they hope will be a deep playoff push. The expectations are real, the talent is in place, and now it’s time for Washington to deliver—starting with a commanding performance against a struggling divisional foe.

New York vs. Washington Prop Picks (AI)

Remi is pouring through loads of data on each player. In fact, anytime the Giants and Commanders play there’s always several intriguing angles to key in on. Not to mention games played at Northwest Stadium in Sep almost always follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: R. Wilson under 225.5 Passing Yards.

New York vs. Washington Prediction (AI)

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Remi, our AI sports algorithm, has been pouring over mountains of data from every facet between the Giants and Commanders and using recursive machine learning and industry leading AI to crunch the data to a single cover probability.

Oddly enough, we’ve seen the AI has been most fixated on the trending emphasis human bettors regularly put on New York’s strength factors between a Giants team going up against a possibly rested Commanders team. Trends look to say the true game analytics appear to reflect a strong lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our NFL AI picks for FREE now.

Below is our current AI New York vs Washington picks, computer picks Giants vs Commanders, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NFL Schedule.

Giants Betting Trends

The Giants went just 5‑12 against the spread (29.4 %) in 2024 and failed to cover in either head‑to‑head game against Washington last season.

Commanders Betting Trends

The Commanders covered an impressive 12‑7‑1 (63.2 %) ATS in 2024 as they surged to the NFC Championship game.

Giants vs. Commanders Matchup Trends

Despite Washington’s strong ATS history and dominance over New York last season, the 7‑point opening line reflects both confidence in their growth and skepticism about whether the Giants can stay competitive in divisional road openers.

New York vs. Washington Game Info

New York vs Washington starts on September 07, 2025 at 1:00 PM EST.

Spread: Washington -6.5
Moneyline: New York +240, Washington -299
Over/Under: 45.5

New York: (0-0)  |  Washington: (0-0)

Remi's searched hard and found the best prop for this matchup: R. Wilson under 225.5 Passing Yards.. Prices move—always shop for the best number.

Despite Washington’s strong ATS history and dominance over New York last season, the 7‑point opening line reflects both confidence in their growth and skepticism about whether the Giants can stay competitive in divisional road openers.

NYG trend: The Giants went just 5‑12 against the spread (29.4 %) in 2024 and failed to cover in either head‑to‑head game against Washington last season.

WAS trend: The Commanders covered an impressive 12‑7‑1 (63.2 %) ATS in 2024 as they surged to the NFC Championship game.

See our latest NFL picks and odds pages for 2025 to compare prices before you bet.

New York vs. Washington Odds

Remi is pouring through tons of data on each line. In fact, anytime the New York vs Washington trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme temps can often follow normal, predictable patterns.

New York vs Washington Opening Odds

NYG Moneyline: +240
WAS Moneyline: -299
NYG Spread: +6.5
WAS Spread: -6.5
Over/Under: 45.5

New York vs Washington Live Odds

Games PTS ML SPR O/U
Oct 9, 2025 8:15PM EDT
Philadelphia Eagles
New York Giants
10/9/25 8:15PM
Eagles
Giants
-410
+325
-7.5 (-105)
+7.5 (-115)
O 40.5 (-110)
U 40.5 (-110)
Oct 12, 2025 9:30AM EDT
Denver Broncos
New York Jets
10/12/25 9:30AM
Broncos
Jets
-405
+320
-7 (-118)
+7 (-104)
O 43.5 (-105)
U 43.5 (-115)
Oct 12, 2025 1:00PM EDT
Seattle Seahawks
Jacksonville Jaguars
10/12/25 1PM
Seahawks
Jaguars
-108
-112
+1.5 (-125)
-1.5 (+105)
O 47.5 (-110)
U 47.5 (-110)
Oct 12, 2025 1:00PM EDT
New England Patriots
New Orleans Saints
10/12/25 1PM
Patriots
Saints
-205
+170
-3.5 (-110)
+3.5 (-110)
O 45.5 (-118)
U 45.5 (-102)
Oct 12, 2025 1:01PM EDT
Cleveland Browns
Pittsburgh Steelers
10/12/25 1:01PM
Browns
Steelers
+215
-265
+5.5 (-110)
-5.5 (-110)
O 37.5 (-115)
U 37.5 (-105)
Oct 12, 2025 1:01PM EDT
Los Angeles Chargers
Miami Dolphins
10/12/25 1:01PM
Chargers
Dolphins
-225
+185
-4.5 (-108)
+4.5 (-112)
O 44.5 (-102)
U 44.5 (-118)
Oct 12, 2025 1:01PM EDT
Los Angeles Rams
Baltimore Ravens
10/12/25 1:01PM
Rams
Ravens
-380
+300
-7.5 (-105)
+7.5 (-115)
O 44.5 (-110)
U 44.5 (-110)
Oct 12, 2025 1:01PM EDT
Dallas Cowboys
Carolina Panthers
10/12/25 1:01PM
Cowboys
Panthers
-165
+142
-3 (-105)
+3 (-115)
O 49.5 (-110)
U 49.5 (-110)
Oct 12, 2025 1:01PM EDT
Arizona Cardinals
Indianapolis Colts
10/12/25 1:01PM
Cardinals
Colts
+275
-340
+7 (-105)
-7 (-115)
O 47 (-110)
U 47 (-110)
Oct 12, 2025 4:06PM EDT
Tennessee Titans
Las Vegas Raiders
10/12/25 4:06PM
Titans
Raiders
+185
-225
+4.5 (-110)
-4.5 (-110)
O 41.5 (-112)
U 41.5 (-108)
Oct 12, 2025 4:26PM EDT
Cincinnati Bengals
Green Bay Packers
10/12/25 4:26PM
Bengals
Packers
+675
-1050
+14 (-105)
-14 (-115)
O 44.5 (-110)
U 44.5 (-110)
Oct 12, 2025 4:26PM EDT
San Francisco 49ers
Tampa Bay Buccaneers
10/12/25 4:26PM
49ers
Buccaneers
+136
-162
+3 (-105)
-3 (-115)
O 47.5 (-110)
U 47.5 (-110)
Oct 12, 2025 8:20PM EDT
Detroit Lions
Kansas City Chiefs
10/12/25 8:20PM
Lions
Chiefs
+120
-142
+2.5 (-110)
-2.5 (-110)
O 52.5 (-115)
U 52.5 (-105)
Oct 13, 2025 7:15PM EDT
Buffalo Bills
Atlanta Falcons
10/13/25 7:15PM
Bills
Falcons
-225
+185
-4.5 (-115)
+4.5 (-105)
O 49.5 (-118)
U 49.5 (-102)
Oct 13, 2025 8:16PM EDT
Chicago Bears
Washington Commanders
10/13/25 8:16PM
Bears
Commanders
+185
-225
+4.5 (-105)
-4.5 (-115)
O 49.5 (-118)
U 49.5 (-102)
Oct 16, 2025 8:16PM EDT
Pittsburgh Steelers
Cincinnati Bengals
10/16/25 8:16PM
Steelers
Bengals
-225
+185
-4.5 (-110)
+4.5 (-110)
O 43.5 (-110)
U 43.5 (-110)

NFL Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers New York Giants vs. Washington Commanders on September 07, 2025 at Northwest Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our NFL odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
HOU@BAL HOU -125 58.5% 7 WIN
DET@CIN DET -10 55.6% 5 WIN
DAL@NYJ NYJ +1.5 53.7% 3 LOSS
TB@SEA TB +3.5 54.9% 4 WIN
TEN@ARI ARI -7 (BUY 0.5) 54.9% 4 LOSS
DEN@PHI DEN +4.5 57.5% 7 WIN
MIA@CAR TETAIROA MCMILLAN OVER 58.5 RECV YDS 54.5% 4 WIN
LV@IND ASHTON JEANTY UNDER 67.5 RUSH YDS 54.4% 4 WIN
SF@LAR DEMARCUS ROBINSON OVER 29.5 RECV YDS 55.7% 5 WIN
NYJ@MIA NYJ +3 53.8 3 LOSS
CIN@DEN DEN -7.5 54.8 4 WIN
NYJ@MIA OVER 44 52.9% 2 WIN
CIN@DEN UNDER 44.5 53.7% 3 WIN
NYJ@MIA GARRETT WILSON UNDER 9 TARGETS 53.7% 3 WIN
CIN@DEN TEE HIGGINS OVER 6.5 RECV TARGETS 55.5% 5 LOSS
WAS@ATL ATL -2.5 54.3 4 WIN
BAL@KC BAL -2.5 56.3% 6 LOSS
TEN@HOU TEN +7.5 57.9% 7 LOSS
LAC@NYG LAC -6 57.3% 7 LOSS
NO@BUF UNDER 48.5 55.1% 3 LOSS
GB@DAL JAVONTE WILLIAMS UNDER 72.5 RUSH + REC YDS 55.5% 5 LOSS
CAR@NE DRAKE MAYE TO THROW AN INT 56.6% 6 LOSS
SEA@ARI SEA -125 57.7% 6 WIN
SEA@ARI KYLER MURRAY TO THROW AN INT 56.6% 6 WIN
DET@BAL JAHMYR GIBBS OVER 0.5 RUSH TDS 55.8% 5 WIN
DAL@CHI DAL -120 58.7% 6 LOSS
PIT@NE PIT -116 60.1% 6 WIN
ATL@CAR ATL -4.5 55.4% 5 LOSS
LV@WAS LV +3 54.3% 4 LOSS
GB@CLE GB -7 54.3% 4 LOSS
ARI@SF ARI +3 57.7% 6 WIN
KC@NYG PATRICK MAHOMES OVER 230.5 PASS YDS 54.7% 4 WIN
GB@CLE JOE FLACCO OVER 37.5 PASS ATT 56.6% 6 LOSS
MIA@BUF TYREEK HILL OVER 5.5 TOTAL RECEPTIONS 56.8% 6 LOSS
LAC@LV LAC -3 54.9% 4 WIN
TB@HOU BAKER MAYFIELD OVER 1.5 PASS TDS 54.4% 4 WIN
CHI@DET DET -6.5 54.3% 4 WIN
DEN@IND DEN -118 60.1% 10 LOSS
PHI@KC PHI -115 56.7% 6 WIN
SF@NO SF -3 58.8% 8 WIN
SEA@PIT OVER 40 54.9% 4 WIN
CAR@ARI BRYCE YOUNG INTERCEPTIONS UNDER 0.5 56.4% 6 LOSS
DEN@IND JOSH DOWNS RECEPTIONS OVER 3.5 54.7% 4 WIN
ATL@MIN BIJAN ROBINSON RUSH + REC YDS OVER 94.5 53.4% 3 WIN
WAS@GB WAS +3.5 56.5% 6 LOSS
WAS@GB JORDAN LOVE OVER 5.5 RUSH YDS 54.7% 4 WIN
MIN@CHI CALEB WILLIAMS OVER 219.5 PASS YDS 53.4% 3 LOSS
TEN@DEN DEN -8.5 55.3% 5 LOSS
SF@SEA SF -115 54.6% 4 WIN
SF@SEA KENNETH WALKER III UNDER 79.5 RUSH+REC YDS 54.6% 4 WIN
CAR@JAC TANK BIGSBY OVER 10.5 RUSH ATT 56.1% 6 LOSS