Giants vs Commanders Prediction — AI Finds CAN'T MISS NFL Lines & Props (Sep 07)

Updated: 2025-08-31T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The New York Giants open the 2025 NFL season on Sunday, September 7 at 1:00 PM ET, taking on the Washington Commanders at Northwest Stadium in Landover, MD. The Commanders enter as 7-point home favorites with an over/under of 45.5 points.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Sep 07, 2025

Start Time: 1:00 PM EST​

Venue: Northwest Stadium​

Commanders Record: (0-0)

Giants Record: (0-0)

OPENING ODDS

NYG Moneyline: +240

WAS Moneyline: -299

NYG Spread: +6.5

WAS Spread: -6.5

Over/Under: 45.5

NYG
Betting Trends

  • The Giants went just 5‑12 against the spread (29.4 %) in 2024 and failed to cover in either head‑to‑head game against Washington last season.

WAS
Betting Trends

  • The Commanders covered an impressive 12‑7‑1 (63.2 %) ATS in 2024 as they surged to the NFC Championship game.

MATCHUP TRENDS

  • Despite Washington’s strong ATS history and dominance over New York last season, the 7‑point opening line reflects both confidence in their growth and skepticism about whether the Giants can stay competitive in divisional road openers.

NYG vs. WAS
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: R. Wilson under 225.5 Passing Yards.

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New York vs Washington Prediction & Odds:
Free NFL Betting Insights for 9/7/25

The 2025 NFL season kicks off with a classic NFC East rivalry as the Washington Commanders host the New York Giants on Sunday, September 7, in a matchup that clearly reflects the changing landscape of the division. Washington enters as a 7-point favorite, a fair reflection of the momentum they bring from a 12–5 campaign that saw them reach the NFC Championship Game behind the electrifying play of quarterback Jayden Daniels. The Commanders appear to be a team on the rise, with a retooled offense that now features big-name additions like Deebo Samuel and Laremy Tunsil, along with a defense anchored by veterans such as Bobby Wagner and Von Miller. Meanwhile, the Giants are coming off a disastrous 3–14 season that left more questions than answers, particularly at the quarterback position where veteran Russell Wilson is expected to start while top rookie Jaxson Dart waits in the wings. New York also struggled mightily against the spread last year, finishing with a 5–12 ATS record and failing to cover in either game against Washington. Offensively, the Giants hope rookie wideout Malik Nabers can be a game-changer, but the offensive line remains a major concern, especially against a pass rush as aggressive and disciplined as Washington’s.

The betting total sits around 45.5 points, which suggests a moderate pace and some scoring opportunities, but that may rely more on Washington’s ability to execute than any expectations from New York. Defensively, the Giants have added talent with players like Abdul Carter, but cohesion and experience are lacking, especially in the secondary. For the Commanders, this game presents an opportunity to assert their place at the top of the division and take care of business against a rebuilding rival. If Jayden Daniels can manage the game, extend drives with his legs, and avoid turnovers, Washington should be able to dictate the pace, especially at home. For the Giants to cover or pull off a shocking upset, they’ll need to win the turnover battle, control the clock with efficient short-yardage plays, and find ways to generate points from special teams or defensive stands. History, recent form, and roster composition all point toward a commanding Washington win, but Week 1 games have a tendency to surprise—especially when desperation meets opportunity. However, given how both teams trended last season, anything short of a dominant performance by Washington would be seen as a missed opportunity. The Commanders have the edge in quarterback play, pass protection, pass rush, and overall cohesion, while the Giants are leaning on hope, new faces, and a best-case-scenario performance just to stay competitive. The narrative entering this game is clear: Washington is ready to contend, while the Giants are hoping to prove they still belong.

New York Giants NFL Preview

The New York Giants enter the 2025 season with low expectations after a brutal 3–14 campaign that saw them finish with one of the worst records and worst against-the-spread marks in the league. Their 5–12 ATS record from last year reflects a team that consistently underperformed and struggled to stay competitive, particularly in divisional matchups where they failed to cover in either game against the Commanders. The offseason offered a chance to hit the reset button, and the organization attempted to do so by drafting quarterback Jaxson Dart and signing veterans Russell Wilson and Jameis Winston to bridge the gap under center. For now, Wilson is expected to start Week 1, though he will be operating behind an offensive line that remains one of the most unstable in the league. There is optimism surrounding wide receiver Malik Nabers, who showed elite explosiveness in preseason and has already emerged as the top target in the passing game, while tight end Darren Waller offers a reliable presence over the middle. Saquon Barkley’s departure has left the run game in the hands of a committee, which could present early inefficiencies against a defense like Washington’s that excels at clogging the box and collapsing lanes. On defense, rookie pass rusher Abdul Carter adds speed and power off the edge, but the secondary lacks depth and could struggle to keep pace with Washington’s wideouts.

The Giants must also overcome their recent history at FedEx Field, where they’ve struggled to generate consistent offense and frequently fell behind early, putting pressure on a passing attack that lacks rhythm. If New York hopes to stay competitive or cover the spread, it will require a near-perfect performance from Wilson, mistake-free football, and opportunistic defense that can turn takeaways into points. Head coach Brian Daboll enters a critical year, with questions about whether his 2022 playoff run was a fluke or a glimpse of unrealized potential. The offensive playcalling must be more aggressive but also calculated to keep pressure off the quarterback and shorten the game. Defensively, stopping Jayden Daniels from extending plays and controlling the clock will be paramount, as Washington’s offense thrives on tempo and spacing. The Giants will need to win situational downs—third downs, red zone, and two-minute drills—to have any chance of success. Special teams may be the hidden X-factor, with the Giants needing to flip the field and generate momentum from return opportunities or key punts. Still, based on recent history, personnel matchups, and form, the Giants face an uphill battle on the road in Week 1, and while it’s not impossible for them to keep things close, they must be near flawless in execution to do so. In what’s shaping up to be a tough year for New York, this opener against a surging division rival will be an early test of both resolve and direction.

The New York Giants open the 2025 NFL season on Sunday, September 7 at 1:00 PM ET, taking on the Washington Commanders at Northwest Stadium in Landover, MD. The Commanders enter as 7-point home favorites with an over/under of 45.5 points. New York vs Washington AI Prediction: Free NFL Betting Insights for Sep 07. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Washington Commanders NFL Preview

The Washington Commanders enter the 2025 NFL season with a wave of momentum and a rare sense of stability as they open Week 1 at home against the division rival New York Giants. After a breakout 12–5 campaign that culminated in an NFC Championship Game appearance, Washington has become one of the league’s most intriguing young contenders, led by the electric Jayden Daniels at quarterback. Daniels returns after a sensational rookie season in which he accounted for over 4,400 total yards and 32 touchdowns, displaying poise, explosiveness, and leadership well beyond his years. The offseason only added more firepower to this roster, as the Commanders acquired All-Pro wideout Deebo Samuel to pair with Terry McLaurin and also fortified the offensive line by signing Laremy Tunsil to protect Daniels’ blind side. On defense, head coach Dan Quinn has rebuilt the front seven into a fast, physical unit anchored by Bobby Wagner, Von Miller, and a disruptive defensive line that’s expected to give the Giants’ offense major problems. Washington’s defensive success last year—especially in forcing turnovers and shutting down third downs—translated into a stellar 12–7–1 record against the spread, and they covered easily in both games against the Giants, including a dominant win at home. Entering this matchup as 7-point favorites, the Commanders will look to assert themselves early, taking advantage of a New York team still trying to find its identity and break in new personnel, including at quarterback.

Daniels’ mobility will be especially dangerous against a Giants defense that struggled to contain dual-threat quarterbacks last year, and with McLaurin, Samuel, and tight end Logan Thomas creating mismatches downfield, Washington’s offense should find plenty of opportunities. The run game will also play a pivotal role, with the addition of Austin Ekeler giving the Commanders a dynamic backfield option who excels as both a rusher and receiver. Defensively, Washington will likely deploy a variety of looks to confuse Russell Wilson, challenge a shaky Giants offensive line, and pressure him into mistakes. The home crowd at FedEx Field will be fired up to kick off what is shaping up to be a promising season, and the Commanders have all the tools to deliver a statement performance in their opener. Special teams have also improved, with kicker Brandon McManus and punter Tress Way giving the team dependable veterans in key field position situations. The coaching staff, now in its second full year with Quinn at the helm, brings continuity and a clearer identity on both sides of the ball. If Washington sticks to its formula—ball control, pressure defense, and explosive vertical plays—they should not only win but also cover the spread convincingly. This game presents an ideal setting for the Commanders to reinforce their status as legitimate NFC contenders and set the tone for what they hope will be a deep playoff push. The expectations are real, the talent is in place, and now it’s time for Washington to deliver—starting with a commanding performance against a struggling divisional foe.

New York vs. Washington Prop Picks (AI)

Remi is pouring through loads of data on each player. In fact, anytime the Giants and Commanders play there’s always several intriguing angles to key in on. Not to mention games played at Northwest Stadium in Sep seemingly never follow normal, predictable patterns.
Remi's searched hard and found the best prop for this matchup: R. Wilson under 225.5 Passing Yards.

New York vs. Washington Prediction (AI)

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Remi, our AI sports genius, has been pouring over mountains of data from every angle between the Giants and Commanders and using recursive machine learning and cutting-edge AI to analyze the data to a single cover probability.

Oddly enough, we’ve seen the AI has been most keyed in on the linear correlation of emphasis knucklehead sportsbettors often put on player performance factors between a Giants team going up against a possibly rested Commanders team. Trends look to say the true game analytics might reflect a moderate lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our NFL AI picks for FREE now.

Below is our current AI New York vs Washington picks, computer picks Giants vs Commanders, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
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Giants Betting Trends

The Giants went just 5‑12 against the spread (29.4 %) in 2024 and failed to cover in either head‑to‑head game against Washington last season.

Commanders Betting Trends

The Commanders covered an impressive 12‑7‑1 (63.2 %) ATS in 2024 as they surged to the NFC Championship game.

Giants vs. Commanders Matchup Trends

Despite Washington’s strong ATS history and dominance over New York last season, the 7‑point opening line reflects both confidence in their growth and skepticism about whether the Giants can stay competitive in divisional road openers.

New York vs. Washington Game Info

New York vs Washington starts on September 07, 2025 at 1:00 PM EST.

Spread: Washington -6.5
Moneyline: New York +240, Washington -299
Over/Under: 45.5

New York: (0-0)  |  Washington: (0-0)

Remi's searched hard and found the best prop for this matchup: R. Wilson under 225.5 Passing Yards.. Prices move—always shop for the best number.

Despite Washington’s strong ATS history and dominance over New York last season, the 7‑point opening line reflects both confidence in their growth and skepticism about whether the Giants can stay competitive in divisional road openers.

NYG trend: The Giants went just 5‑12 against the spread (29.4 %) in 2024 and failed to cover in either head‑to‑head game against Washington last season.

WAS trend: The Commanders covered an impressive 12‑7‑1 (63.2 %) ATS in 2024 as they surged to the NFC Championship game.

See our latest NFL picks and odds pages for 2025 to compare prices before you bet.

New York vs. Washington Odds

Remi is pouring through loads of stats on each player. In fact, anytime the New York vs Washington trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme travel distance seemingly never follow normal, predictable patterns.

New York vs Washington Opening Odds

NYG Moneyline: +240
WAS Moneyline: -299
NYG Spread: +6.5
WAS Spread: -6.5
Over/Under: 45.5

New York vs Washington Live Odds

Games PTS ML SPR O/U
Oct 30, 2025 8:15PM EDT
Baltimore Ravens
Miami Dolphins
10/30/25 8:15PM
Ravens
Dolphins
-440
+344
-7.5 (-110)
+7.5 (-110)
O 51 (-105)
U 51 (-115)
Nov 2, 2025 1:00PM EST
Chicago Bears
Cincinnati Bengals
11/2/25 1PM
Bears
Bengals
-160
+140
-2.5 (-125)
+2.5 (+105)
O 51.5 (-104)
U 51.5 (-116)
Nov 2, 2025 1:00PM EST
Indianapolis Colts
Pittsburgh Steelers
11/2/25 1PM
Colts
Steelers
-171
+150
-3 (-117)
+3 (-103)
O 50.5 (-110)
U 50.5 (-110)
Nov 2, 2025 1:00PM EST
Carolina Panthers
Green Bay Packers
11/2/25 1PM
Panthers
Packers
+613
-900
+13 (-105)
-13 (-115)
O 44 (-110)
U 44 (-110)
Nov 2, 2025 1:00PM EST
Atlanta Falcons
New England Patriots
11/2/25 1PM
Falcons
Patriots
+207
-250
+5 (-105)
-5 (-115)
O 45 (-110)
U 45 (-110)
Nov 2, 2025 1:00PM EST
Denver Broncos
Houston Texans
11/2/25 1PM
Broncos
Texans
+105
-125
+1 (+100)
-1 (-120)
O 40 (-110)
U 40 (-110)
Nov 2, 2025 1:00PM EST
San Francisco 49ers
New York Giants
11/2/25 1PM
49ers
Giants
-147
+127
-2.5 (-115)
+2.5 (-105)
O 49 (-103)
U 49 (-117)
Nov 2, 2025 1:00PM EST
Los Angeles Chargers
Tennessee Titans
11/2/25 1PM
Chargers
Titans
-500
+383
-9.5 (-105)
+9.5 (-115)
O 43.5 (-108)
U 43.5 (-112)
Nov 2, 2025 1:00PM EST
Minnesota Vikings
Detroit Lions
11/2/25 1PM
Vikings
Lions
+374
-485
+9 (-110)
-9 (-110)
O 47.5 (-117)
U 47.5 (-103)
Nov 2, 2025 4:05PM EST
New Orleans Saints
Los Angeles Rams
11/2/25 4:05PM
Saints
Rams
+754
-1200
+13.5 (+100)
-13.5 (-120)
O 44 (-107)
U 44 (-113)
Nov 2, 2025 4:05PM EST
Jacksonville Jaguars
Las Vegas Raiders
11/2/25 4:05PM
Jaguars
Raiders
-150
+130
-3 (+100)
+3 (-120)
O 44.5 (-110)
U 44.5 (-110)
Nov 2, 2025 4:25PM EST
Kansas City Chiefs
Buffalo Bills
11/2/25 4:25PM
Chiefs
Bills
-130
+110
-2 (-110)
+2 (-110)
O 52.5 (-110)
U 52.5 (-110)
Nov 2, 2025 8:20PM EST
Seattle Seahawks
Washington Commanders
11/2/25 8:20PM
Seahawks
Commanders
-163
+143
-3 (-113)
+3 (-107)
O 48 (-110)
U 48 (-110)
Nov 3, 2025 8:15PM EST
Arizona Cardinals
Dallas Cowboys
11/3/25 8:15PM
Cardinals
Cowboys
+130
-150
+2.5 (-105)
-2.5 (-115)
O 53.5 (-105)
U 53.5 (-115)
Nov 6, 2025 8:15PM EST
Las Vegas Raiders
Denver Broncos
11/6/25 8:15PM
Raiders
Broncos
+370
-480
+9.5 (-106)
-9.5 (-114)
O 42.5 (-110)
U 42.5 (-110)
Nov 9, 2025 9:30AM EST
Atlanta Falcons
Indianapolis Colts
11/9/25 9:30AM
Falcons
Colts
+290
-360
+7 (-106)
-7 (-114)
O 48.5 (-110)
U 48.5 (-110)

NFL Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers New York Giants vs. Washington Commanders on September 07, 2025 at Northwest Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our NFL odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
TB@NO TB -3.5 52.3% 1 WIN
GB@PIT GB -2.5 52.3% 1 WIN
SF@HOU SF +2.5 56.0% 6 LOSS
NYG@PHI NYG +7.5 53.9% 3 LOSS
BUF@CAR CAR +7.5 54.2% 3 LOSS
DAL@DEN DAL +3.5 55.0% 4 LOSS
MIA@ATL MIA +7 54.3% 4 WIN
CLE@NE CLE +7 56.8% 6 LOSS
TB@NO BAKER MAYFIELD OVER 15.5 RUSH YDS 56.6% 6 LOSS
MIN@LAC JUSTIN HERBERT PASS ATT UNDER 35.5 55.5% 5 WIN
TB@DET TB +6.5 54.4% 4 LOSS
TB@DET RACHAAD WHITE UNDER 14.5 RUSH ATT 54.4% 4 WIN
NE@TEN NE -6.5 55.2% 5 WIN
CAR@NYJ CAR -110 57.4 4 WIN
PHI@MIN PHI -130 58.0% 6 WIN
GB@ARI ARI +7 54.8% 5 WIN
NO@CHI NO +4.5 57.4% 7 LOSS
WAS@DAL JAYDEN DANIELS 1H RUSH YDS OVER 22.5 56.1% 5 WIN
GB@ARI JORDAN LOVE 1Q PASS YDS OVER 54.5 56.6% 6 WIN
PIT@CIN JONNU SMITH RECEPTIONS OVER 3.5 55.3% 5 LOSS
BUF@ATL BUF -3.5 54.7% 4 LOSS
CHI@WAS JAYDEN DANIELS OVER 1.5 PASS TDS 56.6% 6 WIN
TEN@LV UNDER 42 54.8% 3 WIN
DET@KC DET +2.5 55.7% 7 LOSS
SEA@JAC SEA -112 55.7% 5 WIN
LAC@MIA LAC -3.5 54.0% 3 LOSS
ARI@IND IND -8.5 55.6% 5 LOSS
TEN@LV TEN +4.5 56.7% 6 LOSS
LAR@BAL LAR -7 56.2% 6 WIN
SF@TB SF +3.5 57.2% 7 LOSS
CLE@PIT JAYLEN WARREN UNDER 46.5 RUSH YDS 54.4% 4 LOSS
DEN@NYJ BREECE HALL OVER 26.5 RECV YDS 55.0% 4 LOSS
KC@JAC UNDER 45.5 54.9% 3 LOSS
KC@JAC PATRICK MAHOMES UNDER 23.5 PASS COMP 56.6% 6 LOSS
HOU@BAL HOU -125 58.5% 7 WIN
DET@CIN DET -10 55.6% 5 WIN
DAL@NYJ NYJ +1.5 53.7% 3 LOSS
TB@SEA TB +3.5 54.9% 4 WIN
TEN@ARI ARI -7 (BUY 0.5) 54.9% 4 LOSS
DEN@PHI DEN +4.5 57.5% 7 WIN
MIA@CAR TETAIROA MCMILLAN OVER 58.5 RECV YDS 54.5% 4 WIN
LV@IND ASHTON JEANTY UNDER 67.5 RUSH YDS 54.4% 4 WIN
SF@LAR DEMARCUS ROBINSON OVER 29.5 RECV YDS 55.7% 5 WIN
NYJ@MIA NYJ +3 53.8 3 LOSS
CIN@DEN DEN -7.5 54.8 4 WIN
NYJ@MIA OVER 44 52.9% 2 WIN
CIN@DEN UNDER 44.5 53.7% 3 WIN
NYJ@MIA GARRETT WILSON UNDER 9 TARGETS 53.7% 3 WIN
CIN@DEN TEE HIGGINS OVER 6.5 RECV TARGETS 55.5% 5 LOSS
WAS@ATL ATL -2.5 54.3 4 WIN
BAL@KC BAL -2.5 56.3% 6 LOSS