The Baltimore Ravens head into their 2025 season opener with a fierce sense of purpose and a roster constructed to win now, seeking immediate redemption in a rematch against the Buffalo Bills after falling just short in a 27–25 divisional playoff loss last season. Led by former MVP Lamar Jackson, the Ravens are returning the core of a 12–5 team that finished 11–7–1 against the spread in 2024, and they’ve bolstered their offense with even more firepower, most notably by pairing Jackson with bruising All-Pro running back Derrick Henry. This backfield combination gives Baltimore one of the most versatile ground games in the NFL, allowing them to control tempo and tire out defenses through physical drives and play-action opportunities. Jackson remains the ultimate dual-threat, and with young weapons like Zay Flowers and Rashod Bateman maturing into their roles, the passing game has shown signs of deeper vertical chemistry and route precision, particularly when using motion to isolate mismatches. Tight end Mark Andrews continues to be Jackson’s go-to safety valve, especially in high-leverage third-down and red zone scenarios. On the defensive side, the Ravens are still anchored by linebacker Roquan Smith and pass rush specialist Kyle Van Noy, with a veteran secondary featuring Marcus Williams, Brandon Stephens, and the leadership of Marlon Humphrey—if healthy—aiming to shut down Josh Allen’s dynamic passing attack.

Their offseason focus on improving situational defense included upgrading depth at safety and slot corner, positions that were occasionally exposed in their late-season losses. Baltimore thrives as an underdog, particularly on the road, and the early betting market reflects that sharp bettors are siding with them once again in Orchard Park, where the Ravens look to disrupt Buffalo’s home dominance with pressure defense and smart, controlled offensive play. Special teams remain a strength, with Justin Tucker giving the team elite range and consistency on field goals, and Devin Duvernay continuing as a dangerous return man who can flip field position. One of Baltimore’s primary strategic advantages in this matchup lies in their ability to keep games close and dictate physicality, forcing opponents into one-dimensional play in the second half. If Jackson can avoid early turnovers and keep the offense ahead of the chains, and if the defense can generate even modest pressure on Allen without overcommitting, the Ravens are well-positioned to challenge the Bills for a full 60 minutes. The coaching tandem of John Harbaugh and new offensive coordinator Todd Monken gives them schematic creativity and postseason experience that will be critical in managing tempo and making in-game adjustments. With playoff aspirations and championship goals in mind, Baltimore knows this game represents more than just Week 1—it’s a statement opportunity, a chance to flip last year’s result, and a measuring stick for how far this version of the Ravens can go in 2025.